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Journal articles on the topic 'MRCoNS'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Abeygoonawardena, Harshi, Ishan De Zoysa, Radmy Amaya, Aindralal Balasuriya, and Nilanthi Senanayke. "Epidemiology and vancomycin susceptibility pattern of methicillin resistant coagulase negative Staphylococcal (CoNS) isolates from skin swabs of the surgical patients in the National Hospital of Sri Lanka." Ceylon Medical Journal 68, no. 3 (2024): 121–25. http://dx.doi.org/10.4038/cmj.v68i3.9870.

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Background: Coagulase-negative staphylococci (CoNS) are commonly found in human skin as normal flora but are increasingly prevalent in hospital-acquired infec-tions, often exhibiting resistance to methicillin (MRCoNS). Vancomycin is the primary treatment for MRCoNS infections. This study aimed to assess MRCoNS pre-valence in a hospital community and evaluate Vancomycin effectiveness against MRCoNS.Methods: Swabs from 102 hospitalized surgical patients were tested before the surgery for CoNS presence. Methicillin resistance was confirmed using cefoxitin discs. Vancomycin Minimum Inhibitory Conc

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Li, Ying, Jialing Lin, Linghua Li, et al. "Methicillin-Resistant Coagulase-Negative Staphylococci Carriage is a Protective Factor of Methicillin-Resistant Staphylococcus Aureus Nasal Colonization in HIV-Infected Patients: A Cross-Sectional Study." Canadian Journal of Infectious Diseases and Medical Microbiology 2021 (January 12, 2021): 1–8. http://dx.doi.org/10.1155/2021/5717413.

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Background. Methicillin-resistant coagulase-negative Staphylococci (MRCoNS) is regarded as the repository of mecA gene for methicillin-resistant Staphylococcus aureus (MRSA) and may develop methicillin-susceptible Staphylococcus aureus (MSSA) to MRSA. Therefore, we aimed to explore whether MRCoNS carriage is a risk factor of MRSA colonization. Phenotypic characteristics were performed to further assess the associations between MRSA and MRCoNS. Methods. This cross-sectional study was conducted in Guangzhou, China. Participants completed a questionnaire and provided a nasal swab for further anal

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Bonvegna, Miryam, Elena Grego, Bruno Sona, et al. "Occurrence of Methicillin-Resistant Coagulase-Negative Staphylococci (MRCoNS) and Methicillin-Resistant Staphylococcus aureus (MRSA) from Pigs and Farm Environment in Northwestern Italy." Antibiotics 10, no. 6 (2021): 676. http://dx.doi.org/10.3390/antibiotics10060676.

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Swine farming as a source of methicillin-resistant Staphylococcus aureus (MRSA) has been well documented. Methicillin-resistant coagulase-negative staphylococci (MRCoNS) have been less studied, but their importance as pathogens is increasing. MRCoNS are indeed considered relevant nosocomial pathogens; identifying putative sources of MRCoNS is thus gaining importance to prevent human health hazards. In the present study, we investigated MRSA and MRCoNS in animals and environment in five pigsties in a high farm-density area of northwestern Italy. Farms were three intensive, one intensive with an

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Khanal, Muna, Prabhu Raj Joshi, Saroj Paudel, et al. "Methicillin-Resistant Coagulase Negative Staphylococci and Their Antibiotic Susceptibility Pattern from Healthy Dogs and Their Owners from Kathmandu Valley." Tropical Medicine and Infectious Disease 6, no. 4 (2021): 194. http://dx.doi.org/10.3390/tropicalmed6040194.

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This cross-sectional study was designed to identify information on the frequency, antimicrobial resistance and species diversity of methicillin-resistant coagulase negative staphylococci (MRCoNS) among pet dogs and humans within households. Fifty five nasal swabs each from dogs and their owners were collected. MRCoNS were identified based on gram staining, culture on mannitol salt agar, biochemical tests, and mecA gene amplification. The antibiotic susceptibility of the isolates was assessed by a disc diffusion test. Uniplex and multiplex polymerase chain reaction (PCR) were employed for the s

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5

Katkowska, Marta, Maja Kosecka-Strojek, Mariola Wolska-Gębarzewska, et al. "Emerging Challenges in Methicillin Resistance of Coagulase-Negative Staphylococci." Antibiotics 14, no. 1 (2025): 37. https://doi.org/10.3390/antibiotics14010037.

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Objective: In the present study, we used phenotypic and molecular methods to determine susceptibility to oxacillin in coagulase-negative staphylococci (CoNS) and estimate the prevalence of strains with low-level resistance to oxacillin, mecA-positive oxacillin-susceptible methicillin-resistant (OS-MRCoNS), and borderline oxacillin-resistant (BORCoNS). Methods: One hundred one CoNS strains were screened for oxacillin and cefoxitin susceptibility using phenotypic (disk diffusion, agar dilution, latex agglutination, and chromagar) and molecular (detection of mecA, mecB, and mecC) methods. Staphyl

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Ogefere, H. O., G. Umaru, E. E. Ibadin, and R. Omoregie. "Prevalence Of Methicillin-Resistant Staphylococci Among Apparently Healthy Students Attending A Tertiary Institution In Benin City, Nigeria." Nigerian Journal of Basic and Applied Sciences 27, no. 1 (2020): 114–21. http://dx.doi.org/10.4314/njbas.v27i1.15.

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This study was aimed at determining the prevalence of methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistant coagulase negative staphylococci (MRCoNS) among apparently healthy students of a tertiary institution in Benin City, Nigeria. A total of 350 students were recruited for the study and nasal swabs were collected alongside demographic data. These swabs were processed microbiologically using standard techniques to recover staphylococci. Antimicrobial susceptibility and methicillin-resistance was determined using a phenotypic method (cefoxitin resistance). A total of 14

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Røken, Mari, Stanislav Iakhno, Anita Haug Haaland, Ane Mohn Bjelland, and Yngvild Wasteson. "The Home Environment Is a Reservoir for Methicillin-Resistant Coagulase-Negative Staphylococci and Mammaliicocci." Antibiotics 13, no. 3 (2024): 279. http://dx.doi.org/10.3390/antibiotics13030279.

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Coagulase-negative staphylococci (CoNS) and mammaliicocci are opportunistic human and animal pathogens, often resistant to multiple antimicrobials, including methicillin. Methicillin-resistant CoNS (MRCoNS) have traditionally been linked to hospitals and healthcare facilities, where they are significant contributors to nosocomial infections. However, screenings of non-hospital environments have linked MRCoNS and methicillin-resistant mammaliicocci (MRM) to other ecological niches. The aim of this study was to explore the home environment as a reservoir for MRCoNS and MRM. A total of 33 househo

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Prajapati, Bhavesh Ishwarbhai, K. M. SOLANKI, R. D. SINGH, A. C. PATEL, R. M. PATEL, and B. P. KATIRA. "Detection of mecA gene-associated methicillin-resistance coagulase-negative staphylococci (MRCoNS) from bovine mastitis in Gujarat." Indian Journal of Animal Sciences 92, no. 8 (2022): 935–39. http://dx.doi.org/10.56093/ijans.v92i8.105824.

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Exploration of pathogenic potential of Coagulase-Negative Staphylococci (CoNS), in human as well as animals,gained the importance during the past two decades. Emergence of Methicillin-Resistant Coagulase-NegativeStaphylococci (MRCoNS) in bovine milk poses to be a major public health concern. Presence of the mecA gene isone of the most common reasons reported for the methicillin resistant bacteria. Since the scientific data concerningthe presence of mecA gene and MRCoNS in bovine milk is very limited in India, particularly from Gujarat state,the present study was planned to detect mecA gene in

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9

Ishore, Kaushik, Ghosh Prabir, Abhijit Mukherjee, and Santanu Hazra. "Prevalence of Staphylococcal Nasal Carriage Among Health Care Worker Working in Intensive and Critical Care Units of a Tertiary Care Hospital." Journal of Medical Sciences and Health 8, no. 1 (2022): 1–7. http://dx.doi.org/10.46347/jmsh.2022.v8i1.8.

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Background: Incidence of hospital-acquired infection by Methicillin-resistant Staphylococcus aureus (MRSA) and Coagulase-negative Staphylococci (MRCoNS) continues to increase worldwide. Nasal carriage of Staphylococci plays an important role in the epidemiology and pathogenesis of hospital-acquired infection. They are usually introduced into the health care set up by a colonized or infected patient or health care workers (HCWs). Patients admitted to a critical care unit or intensive care unit have an increased chance of infection by these pathogens. Health care providers colonizing MRSA and MR

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Abreu, Rossana, Cristobalina Rodríguez-Álvarez, María Lecuona, et al. "Prevalence and characteristics of methicillin-resistant staphylococci in goats on the island of Tenerife, Spain." Acta Veterinaria Hungarica 67, no. 3 (2019): 317–26. http://dx.doi.org/10.1556/004.2019.033.

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The aim of this study was to determine the prevalence of methicillin-resistant Staphylococcus (MRS) in healthy goats on the Island of Tenerife, Spain, as well as to identify the phenotypic and genotypic characteristics of the strains found. A cross-sectional prevalence study was conducted. A total of 158 goats from 15 different farms were sampled between September 2017 and January 2018. The percentage of positive samples of methicillin-resistant Staphylococcus aureus (MRSA) was 15.8% (25/158) and that of methicillin-resistant coagulase-negative staphylococci (MRCoNS) was 6.9% (11/158). All MRS

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Silva, Vanessa, Manuela Caniça, Eugénia Ferreira, et al. "Multidrug-Resistant Methicillin-Resistant Coagulase-Negative Staphylococci in Healthy Poultry Slaughtered for Human Consumption." Antibiotics 11, no. 3 (2022): 365. http://dx.doi.org/10.3390/antibiotics11030365.

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Coagulase-negative staphylococci are commensals that are known to be prevalent in most environments, and they are also an important reservoir of antimicrobial-resistant genes. Staphylococcal infections in animal husbandry are a high economic burden. Thus, we aimed to determine the prevalence and species diversity of methicillin-resistant coagulase-negative staphylococci (MRCoNS) in poultry slaughtered for human consumption and to study the antimicrobial resistance of the isolates. Swab samples were recovered from 220 commercial chickens, homebred chickens and quails. Species identification was

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12

Soza-Ossandón, Paula, Dácil Rivera, Kasim Allel, et al. "Mec-Positive Staphylococcus Healthcare-Associated Infections Presenting High Transmission Risks for Antimicrobial-Resistant Strains in an Equine Hospital." Antibiotics 11, no. 5 (2022): 621. http://dx.doi.org/10.3390/antibiotics11050621.

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Healthcare-associated infections caused by Staphylococcus, particularly Staphylococcus aureus, represent a high risk for human and animal health. Staphylococcus can be easily transmitted through direct contact with individual carriers or fomites, such as medical and non-medical equipment. The risk increases if S. aureus strains carry antibiotic resistance genes and show a phenotypic multidrug resistance behavior. The aim of the study was to identify and characterize methicillin resistant coagulase-positive staphylococci (MRSA) and coagulase-negative staphylococci (MRCoNS) in equine patients an

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Tiewsoh, Jutang Babat Ain, and Meena Dias. "Screening of methicillin-resistant Staphylococcus aureus in healthcare workers and students and its susceptibility to mupirocin in a tertiary care teaching hospital in South India." Journal of Laboratory Physicians 9, no. 04 (2017): 239–42. http://dx.doi.org/10.4103/0974-2727.214262.

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Abstract BACKGROUND: Staphylococcus is the most common pathogen causing infection in hospitals. They also colonize the healthcare workers who serve as reservoir of infection. Emergence of methicillin-resistant Staphylococcus aureus (MRSA) is a burning issue throughout the world contributing to significant morbidity and mortality. Use of mupirocin to eradicate the carrier state is the need of the hour. OBJECTIVES: To screen healthcare workers (HCWs) and medical students for MRSA and to know the susceptibility of mupirocin in this group. MATERIALS AND METHODS: A total of 432 students, nursing st

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UGWU, Ifeoma Chinyere, Madubuike Umunna ANYANWU, Chidozie Clifford UGWU, and Jude Chukwuemeka OKORO. "Isolation and Detection of Methicillin-Resistant Staphylococci in Healthy Broilers in Nsukka Southeast, Nigeria." Notulae Scientia Biologicae 7, no. 1 (2015): 20–25. http://dx.doi.org/10.15835/nsb719479.

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This study was conducted to isolate and detect methicillin-resistant staphylococci (MRS) in healthy broilers in Nsukka Southeast, Nigeria and determine the antibiogram of the isolates. Cloacal and skin swabs were collected from each of 101 randomly sampled broilers meant for slaughter. The samples were processed for isolation and identification of methicillin-resistant Staphylococcus species, following standard methods. Confirmation of methicillin-resistance by the isolates was done using penicillin binding protein 2a (PBP2a) kit. Phenotypic resistance of the isolates to antimicrobial agents w

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Venugopal, Nimita, Susweta Mitra, Rituparna Tewari, et al. "Molecular detection and typing of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci isolated from cattle, animal handlers, and their environment from Karnataka, Southern Province of India." November-2019 12, no. 11 (2019): 1760–68. http://dx.doi.org/10.14202/vetworld.2019.1760-1768.

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Background and Aim: Methicillin-resistant staphylococci are among the emerging pathogens which have become a threat to both human and animal health. The present investigation intended to examine the occurrence and the molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS) recovered from cattle, its handlers, and their environment. Materials and Methods: A total of 666 specimens were subjected to culture method and genus-specific polymerase chain reaction (PCR) for the identification of Staphylococcus.

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Adiguzel, Mehmet Cemal, Kayla Schaefer, Trevor Rodriguez, Jessica Ortiz, and Orhan Sahin. "Prevalence, Mechanism, Genetic Diversity, and Cross-Resistance Patterns of Methicillin-Resistant Staphylococcus Isolated from Companion Animal Clinical Samples Submitted to a Veterinary Diagnostic Laboratory in the Midwestern United States." Antibiotics 11, no. 5 (2022): 609. http://dx.doi.org/10.3390/antibiotics11050609.

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Methicillin-resistant Staphylococcus (MRS) is a leading cause of skin and soft tissue infections in companion animals, with limited treatment options available due to the frequent cross-resistance of MRS to other antibiotics. In this study, we report the prevalence, species distribution, genetic diversity, resistance mechanism and cross-resistance patterns of MRS isolated from companion animal (mostly dog and cat) clinical cases submitted to Iowa State University Veterinary Diagnostic Laboratory (ISU VDL) between 2012 and 2019. The majority of isolates were identified as Staphylococcus pseudin

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17

Sandhya, Narayanan, S. Deepa, and P.L. Soundarya. "Comparative Evaluation of Vancomycin Disc Diffusion Method & Vancomycin Screen Agar with Vancomycin E-Test in the Detection of Clinically Significant MRCoNS." International Journal of Pharmaceutical and Clinical Research 14, no. 5 (2022): 578–85. https://doi.org/10.5281/zenodo.13829007.

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<strong>Background and Objectives:</strong> <em>Coagulase negative Staphylococci </em>(CoNS) are colonizers of the skin, anterior nares, and ear canals of human beings. They have long been considered as non-pathogenic but as a result of the combination of increased use of intravascular devices and increase in the number of hospitalized immunocompromised patients, they have become one of the important nosocomial pathogens.  One of the characteristics of CoNS is their resistance to multiple antimicrobial agents. Some recent reports have pointed out high level of methicillin resist

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Yazgi, H., MH Uyanik, and A. Ayyildiz. "Comparison of Slime-producing Coagulase-negative Staphylococcus Colonization Rates on Vinyl and Ceramic Tile Flooring Materials." Journal of International Medical Research 37, no. 3 (2009): 668–73. http://dx.doi.org/10.1177/147323000903700309.

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This study investigated the colonization of slime-producing coagulase-negative Staphylococcus (CoNS) in 80 patient wards in Turkey (40 vinyl and 40 ceramic tile floors). A total of 480 samples that included 557 CoNS isolates were obtained. Slime production was investigated with the Christensen method and methicillin-susceptibility was tested by the diskdiffusion method. There was a significant difference in the percentage of slime-producing CoNS isolates on vinyl (12.4%) versus ceramic tile flooring (4.4%). From vinyl flooring, the percentage of slime producing methicillin-resistant CoNS (MRCo

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Vulcanescu, Dan Dumitru, Iulia Cristina Bagiu, Tiberiu Liviu Dragomir, et al. "The Impact of the COVID-19 Pandemic on Pediatric Microbial Resistance Patterns and Abandonment Rates in Western Romania—An Interdisciplinary Study." Antibiotics 14, no. 4 (2025): 411. https://doi.org/10.3390/antibiotics14040411.

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Background: The COVID-19 pandemic in Romania exacerbated pediatric antimicrobial resistance (AMR). Overuse of broad-spectrum antibiotics may be related to increased multidrug-resistant bacteria. The main aim of this study was to assess pediatric AMR trends and phenotypes, while a secondary objective was to investigate the potential links with hospital abandonment. Methods: This retrospective study from the Children’s Emergency Hospital “Louis Țurcanu”, Timișoara, focused on AMR patterns in 2019 pre-pandemic, 2021 pandemic, and 2023 post-pandemic. The following phenotypes were assessed: MRSA, M

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Gonzalbo Falomir, Daniel, Hortensia Rico Vidal, and María Pilar Falomir Llorens. "Commensal Staphylococcus isolates from the nasal cavity of community older adults in Valencia (Spain) and their resistance to methicillin and other antibiotics." European Journal of Health Research 5, no. 2 (2019): 145. http://dx.doi.org/10.30552/ejhr.v5i2.185.

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Methicillin-resistant Staphylococcus aureus strains (MRSA) have been gradually disseminated worldwide, causing nosocomial and community-acquired infections, and healthy carriers of commensal MRSA constitute a reservoir of the pathogen. Other Staphylococcus species (coagulase-negative, CoNS) colonize animals and humans and include also methicillin-resistant strains (MRCoNS). Here we have determined the prevalence of S. aureus and CoNS species in the nasal cavity of community healthy older adults (n= 27, average age: 63.7 years) and their resistance to methicillin and other antibiotics. A total

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Rey, Joaquín, María Gil, Javier Hermoso de Mendoza, et al. "Clonality and Persistence of Multiresistant Methicillin-Resistant Coagulase-Negative Staphylococci Isolated from the Staff of a University Veterinary Hospital." Antibiotics 11, no. 6 (2022): 811. http://dx.doi.org/10.3390/antibiotics11060811.

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The aim of this study was to characterize methicillin-resistant coagulase-negative staphylococci (MRCoNS) isolates from the healthy staff of a university veterinary hospital in order to assess their importance as a reservoir of antimicrobial resistance and to determine their population structure and evolution. The study duration was over two years (2020–2021), 94 individuals were analyzed in duplicate, and 78 strains were obtained. The overall prevalence of methicillin-resistant strains detected throughout the study was 61.7%, with point prevalence values of 53.2% in 2020 and 31.5% in 2021. A

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Nagano, Rie, Kaneyoshi Shibata, Yuka Adachi, Hideaki Imamura, Terutaka Hashizume та Hajime Morishima. "In Vitro Activities of Noveltrans-3,5-Disubstituted Pyrrolidinylthio-1β-Methylcarbapenems with Potent Activities against Methicillin-Resistant Staphylococcus aureus andPseudomonas aeruginosa". Antimicrobial Agents and Chemotherapy 44, № 3 (2000): 489–95. http://dx.doi.org/10.1128/aac.44.3.489-495.2000.

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ABSTRACT The in vitro activities of the novel 1β-methylcarbapenems J-111,225, J-114,870, and J-114,871, which have a structurally unique side chain that consists of a trans-3,5-disubstituted 5-arylpyrrolidin-3-ylthio moiety at the C-2 position, were compared with those of reference antibiotics. Among isolates of both methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MRCoNS), 90% were inhibited by J-111,347 (prototype), J-111,225, J-114,870, and J-114,871 at concentrations of 2, 4, 4, and 4 μg/ml (MICs at which 90% of isolates are inh

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Gostev, V. V., O. S. Sulian, O. S. Kalinogorskaya, et al. "Comparative Activity of Lipoglycopeptide Antibiotics Against Gram-Positive Bacteria." Antibiotics and Chemotherapy 67, no. 9-10 (2022): 18–24. http://dx.doi.org/10.37489/0235-2990-2022-67-9-10-18-24.

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Lipoglycopeptide antibiotics are semi-synthetic derivatives of glycopeptides and are characterized by a pronounced bactericidal activity against gram-positive pathogens. The aim of the study was comparative assessment of the sensitivity of gram-positive clinical isolates to lipoglycopeptide antibiotics (telavancin, dalbavancin, oritavancin). The following isolates were included in the work: methicillin-resistant Staphylococcus aureus (MRSA, n=780), methicillin-resistant coagulase-negative Staphylococcus spp. (MRCoNS, n=163), and vancomycin-resistant Enterococcus faecium (VREf, n=93). Serial di

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Bhargava, Kanika, and Yifan Zhang. "Characterization of methicillin-resistant coagulase-negative staphylococci (MRCoNS) in retail meat." Food Microbiology 42 (September 2014): 56–60. http://dx.doi.org/10.1016/j.fm.2014.02.019.

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Abreu, Rossana, Cristobalina Rodríguez-Álvarez, Beatriz Castro-Hernandez, et al. "Prevalence and Characterisation of Multiresistant Bacterial Strains Isolated in Pigs from the Island of Tenerife." Veterinary Sciences 9, no. 6 (2022): 269. http://dx.doi.org/10.3390/vetsci9060269.

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Background: Antibiotic-resistant bacteria can circulate among human and animal populations through direct contact with animals, as well as via food and the environment. The purpose of this study was to examine the prevalence and characterisation of multiresistant bacteria in pig samples. Methods: 224 samples of pig livestock were taken at the slaughterhouse on the island of Tenerife. A nasal and a rectal sample were collected from each pig. The presence of methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus coagulase-negative (MRCoNS), vancomycin-resistant

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P., Rashmi, and Praveen B. K. "Clinico-bacteriological profile of neonatal sepsis." International Journal of Contemporary Pediatrics 6, no. 2 (2019): 796. http://dx.doi.org/10.18203/2349-3291.ijcp20190732.

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Background: Neonatal sepsis is the commonest cause of neonatal mortality responsible for about 30-50% of total neonatal deaths in developing countries. Surveillance of causative organisms and their antibiotic sensitivity pattern promotes rational use of antibiotics and antibiotic stewardship.Methods: A retrospective study, relevant data regarding the neonates diagnosed with culture positive sepsis was obtained from the case records during the period from July 2014 to June 2017. Culture positive sepsis was defined as isolation of bacterial pathogen from blood in neonates with clinical suspicion

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Martins, Marlene Andrade, Silvana de Lima Vieira dos Santos, Lara Stefânia Netto de Oliveira Leão, Nayara Portilho Araújo, and Maria Márcia Bachion. "Prevalence of resistance phenotypes in Staphylococcus aureus and coagulase-negative isolates of venous ulcers of primary healthcare patients." Revista da Sociedade Brasileira de Medicina Tropical 45, no. 6 (2012): 717–22. http://dx.doi.org/10.1590/s0037-86822012000600012.

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INTRODUCTION: In venous ulcers, the presence of Staphylococcus aureus and coagulase-negative staphylococcus resistance phenotypes can aggravate and limit the choices for treatment. METHODS: Staphylococcus isolated from 69 patients (98 ulcers) between October of 2009 and October of 2010 were tested. The macrolide, lincosamide, streptogramin B (MLS B) group resistance phenotype detection was performed using the D-test. Isolates resistant to cefoxitin and/or oxacillin (disk-diffusion) were subjected to the confirmatory test to detect minimum inhibitory concentration (MIC), using oxacillin strips

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Liu, Yuting, Liqin Chen, Yuping Duan, and Zhen Xu. "Molecular Characterization of Staphylococci Recovered from Hospital Personnel and Frequently Touched Surfaces in Tianjin, China." Canadian Journal of Infectious Diseases and Medical Microbiology 2022 (August 10, 2022): 1–7. http://dx.doi.org/10.1155/2022/1061387.

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Staphylococci are major hospital-associated pathogens, and the dissemination of methicillin-resistant staphylococci in hospitals poses a great challenge for managing hospital-acquired infections. Little is known about the dissemination of staphylococci recovered from the hospital environment and personnel in China. In this study, antimicrobial susceptibility tests, mecA gene detection, SCCmec typing, and multilocus sequence typing (MLST) were performed to clarify the molecular epidemiology of staphylococci in a large hospital in Tianjin, China. One hundred and ninety-five staphylococci were re

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NAZWAR, Tommy Alfandy, Bagus Ramanto SAPUTRA, Dewi RETNONINGSIH, Farhad BALAFIF, and Donny Wisnu WARDHANA. "Prevalence and Antibiotic Resistance of Bacteria Isolated from Cerebrospinal Fluid of Neurosurgical Patients in Malang, Indonesia." Medicina Moderna - Modern Medicine 30, no. 4 (2023): 341–46. http://dx.doi.org/10.31689/rmm.2023.30.4.341.

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Background: Central nervous system infections are a critical concern in neurosurgical practice, often leading to severe complications and prolonged hospital stays. Understanding the prevalence and antibiotic resistance patterns of the bacteria causing these infections is essential for effective patient management. This study aims to investigate the prevalence and antibiotic resistance profiles of bacteria isolated from cerebrospinal fluid in neurosurgical patients in Malang, Indonesia. Materials and Methods: A retrospective analysis was conducted to investigate the positive cerebrospinal fluid

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Mavlyanova, Sh Z., M. M. Eshniyazov, and A. I. Ismogilov. "Clinical, genetic and microbiological aspects in patients with atopic dermatitis and ichthyosis." Terapevt (General Physician), no. 2 (February 18, 2024): 62–68. http://dx.doi.org/10.33920/med-12-2402-06.

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The article presents a comparative assessment of microbiological, clinical, and genetic aspects in patients with atopic dermatitis and ichthyosis. The results of a study in 62 patients with atopic dermatitis and 19 patients with ichthyosis showed that there was a phenomenon of persistence of opportunistic microorganisms Staphylococcus spp. in skin lesion foci. Thus, in the group of the patients with ichthyosis, the development of persistent forms of bacterial infection caused by MRCoNS is noted in 69.2 % of cases, and in the patients with atopic dermatitis, an invasive form of MRSA-associated

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Sukur, H., and OM Esendal. "Presence and antimicrobial resistance of coagulase-negative staphylococci isolated from animals in a Veterinary Teaching Hospital in Cyprus." Veterinární Medicína 65, No. 5 (2020): 191–98. http://dx.doi.org/10.17221/166/2019-vetmed.

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Coagulase-negative staphylococci (CoNS) are a group of commensal microorganisms residing on the skin and mucous membranes of both humans and animals. Until recently, they have been regarded as non-pathogenic to livestock and companion animals, but since then, their clinical importance in veterinary medicine has increased with the discovery of their potential pathogenic roles in animals causing skin and soft tissue infections together with spontaneous abortions and mastitis. Scientific data concerning the presence of CoNS in North Cyprus are very limited. Therefore, the purpose of the study rep

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Johnson, Alan P., Marina Warner, Michael Carter, and David M. Livermore. "In Vitro Activity of Cephalosporin RWJ-54428 (MC-02479) against Multidrug-Resistant Gram-Positive Cocci." Antimicrobial Agents and Chemotherapy 46, no. 2 (2002): 321–26. http://dx.doi.org/10.1128/aac.46.2.321-326.2002.

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ABSTRACT RWJ-54428 (MC-02479) is a novel cephalosporin that binds to penicillin-binding protein (PBP) PBP 2′ (PBP 2a) of methicillin-resistant staphylococci. Its in vitro activity was assessed against 472 gram-positive cocci, largely selected as epidemiologically unrelated isolates with multidrug resistance. The MIC at which 50% of isolates are inhibited (MIC50) and MIC90 of RWJ-54428 for methicillin-resistant Staphylococcus aureus (MRSA) were 1 and 2 μg/ml, respectively, whereas they were 0.5 and 0.5 μg/ml, respectively, for methicillin-susceptible S. aureus. The MIC50 and MIC90 were 1 and 4

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Pratulya, Nandan, and Sharan Swati. "Prospective Observational Research to Determine Antimicrobial Susceptibility and Biofilm Production among Coagulase Negative Staphylococci." International Journal of Pharmaceutical and Clinical Research 14, no. 1 (2022): 666–71. https://doi.org/10.5281/zenodo.13868165.

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<strong>Aim:</strong> To determine antimicrobial susceptibility and biofilm production among coagulase negative staphylococci at a tertiary care hospital. <strong>Materials and Methods:</strong> This prospective observational study was carried out in the Department of Microbiology, Patna Medical College, Patna, Bihar, India for 10 months.  Purely isolated CoNS from various clinical samples from both outpatients and inpatients included in this study. All the test strains were subjected to antimicrobial susceptibility testing. The ability to produce biofilm was detected by tu

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Bathala, Naga Sri Latha, M. Sasidhar, and S. Kusuma Bai. "To determine antimicrobial susceptibility and biofilm production among coagulase negative staphylococci at a tertiary care hospital." Indian Journal of Microbiology Research 8, no. 3 (2021): 230–34. http://dx.doi.org/10.18231/j.ijmr.2021.047.

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CoNS are gaining importance due to increase in resistance rates to betalactam antibiotics and multi drug resistance. Although specific virulence factors are not as clearly established, it seems clear that factors such as bacterial polysaccharide components, and ability to form biofilm are involved in attachment and/or persistence of bacteria on foreign materials. Biofilms usually result in persistent infections that cannot be easily resolved with standard antibiotic treatments; therefore, the biofilm formation ability and the resistance to antimicrobial therapy can be intimately related. A pro

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Ruiz-Ripa, Laura, Paula Gómez, Carla Andrea Alonso, et al. "Frequency and Characterization of Antimicrobial Resistance and Virulence Genes of Coagulase-Negative Staphylococci from Wild Birds in Spain. Detection of tst-Carrying S. sciuri Isolates." Microorganisms 8, no. 9 (2020): 1317. http://dx.doi.org/10.3390/microorganisms8091317.

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The objective of this study was to determine the prevalence and diversity of coagulase-negative staphylococci (CoNS) species from wild birds in Spain, as well as to analyze the antimicrobial resistance phenotype/genotype and the virulence gene content. During 2015–2016, tracheal samples of 242 wild birds were collected in different regions of Spain for staphylococci recovery. The species identification was performed using MALDI-TOF. The antimicrobial resistance phenotype and genotype was investigated by the disk diffusion method and by PCR, respectively. The presence of the virulence genes luk

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Godoy dos Santos, Alexandre Leme, Guilherme Honda, Priscila Rosalba, Rafael Barban Sposeto, Tulio Diniz Fernandes, and Ana Lucia Lei Munhoz Lima. "PO 18105 - Diabetic foot ulcer PEDIS III." Scientific Journal of the Foot & Ankle 13, Supl 1 (2019): 13S. http://dx.doi.org/10.30795/scijfootankle.2019.v13.1014.

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Introduction: Infectious agents are associated with amputation of the infected diabetic foot if not promptly treated. It is estimated that 25% of patients with diabetes will present with a foot ulcer at some point of their lives. Our hypothesis is that the microbiological profile isolated from chronic osteomyelitis (CO) secondary to neuropathic foot ulcers is different from the standard profile relayed in the literature. Objective: To determine the microbiological profile and antimicrobial susceptibility patterns of organisms isolated from chronic osteomyelitis (CO) secondary to neuropathic fo

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Snehasara, Jaiboi K., and A. Sathiavathy K. "Detection and Prevalence of Inducible Clindamycin Resistance in Staphylococcus Species: Insights from a Tertiary Care Centre in Kerala." International Journal of Pharmaceutical and Clinical Research 16, no. 11 (2024): 1322–29. https://doi.org/10.5281/zenodo.14476331.

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<strong>Introduction:</strong> With the emergence of many multidrug resistant organisms like methicillin resistant Staphylococci, therapeutic options for treating skin and soft tissue infections have become severely limited. Clindamycin is an attractive option for the treatment of such cases especially Community-acquired MRSA (CA-MRSA) because of its excellent tissue penetration and it can be used in penicillin-allergic patients also. But clinical failure can occur due to multiple mechanisms that confer resistance to Macrolide, Lincosamide and Streptogramin B antibiotics. This study was c

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Harsh H. Patel, Harsha D. Makwana, and Supriya D. Malhotra. "Linezolid Induced Thrombocytopenia: A Case Report." Innovative Journal of Medical and Health Science 11, no. 05 (2021): 1702–4. http://dx.doi.org/10.15520/ijmhs.v11i05.3307.

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Linezolid (LZD) is an antimicrobial agent with a broad spectrum of activity against virtually all clinically important Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCoNS) and vancomycin-resistant enterococci (VRE). Thrombocytopenia (TP) is a common adverse effect of Linezolid (LZD). Prolonged treatment duration, renal insufficiency, chronic liver disease, malignancy, previous vancomycin use, baseline platelet count, and lower body weight have been reported as possible risk factors for LZD-associat

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Ibrahim, I., H. Hasan, and Z. Abdul Rahman. "PP-035 Environmental surveillance for methicillin resistance coagulase negative staphylococci (MRCoNS) in Hospital Universiti Sains Malaysia (HUSM)." International Journal of Infectious Diseases 14 (July 2010): S35. http://dx.doi.org/10.1016/s1201-9712(10)60103-8.

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Asbell, Penny A., and Christine M. Sanfilippo. "Antibiotic Resistance Trends Among Ocular Pathogens in the US—Cumulative Results from the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) Surveillance Study." US Ophthalmic Review 10, no. 01 (2017): 35. http://dx.doi.org/10.17925/usor.2017.10.01.35.

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Antibiotic resistance among ocular pathogens is a public health concern. The multicenter, prospective Antibiotic Resistance Monitoring in Ocular micRoorganisms (ARMOR) study is an ongoing surveillance study designed to report on antibiotic resistance rates and trends among Staphylococcus aureus, coagulase-negative staphylococci (CoNS; includes Staphylococcus epidermidis), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates from ocular infections. Results for more than 4,000 isolates collected from 2009 –2015, representing 7 years of ARMOR, were recently presen

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Madhuri, Sweta Jangra, and Manisha Khandait. "Clinical Spectrum and Resistance Profile of Staphylococcus Infections in a Peri Urban Tertiary Care Hospital." Journal of Pure and Applied Microbiology 15, no. 4 (2021): 2163–69. http://dx.doi.org/10.22207/jpam.15.4.39.

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Staphylococcus may be evaluated to be a serious microorganism to colonizes and contaminate both the healthy and immuno-competent people in the community along with the hospitalized patients with decreased immunity. This bacterium has been commonly present on the skin and in the nasal cavity of the human body. In the particular sites the organisms may give rise to local diseases of the nose, urethra, vagina and gastrointestinal tract, skin however most of them are minor and not associated with any mortality. S. aureus as well as coagulase-negative staphylococcus which are gram-positive bacteria

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Chung, Yousun, Taek Soo Kim, Young Gi Min, et al. "Usefulness of Multiplex Real-Time PCR for Simultaneous Pathogen Detection and Resistance Profiling of Staphylococcal Bacteremia." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/6913860.

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Staphylococci are the leading cause of nosocomial blood stream infections. Fast and accurate identification of staphylococci and confirmation of their methicillin resistance are crucial for immediate treatment with effective antibiotics. A multiplex real-time PCR assay that targetsmecA,femAspecific forS. aureus,femAspecific forS. epidermidis,16S rRNAfor universal bacteria, and16S rRNAspecific for staphylococci was developed and evaluated with 290 clinical blood culture samples containing Gram-positive cocci in clusters (GPCC). For the 262 blood cultures identified to the species level with the

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Zani, Kathleen, Joseph Hobeika, Yilun Sun, et al. "Nasal microbiota predictors for methicillin resistant Staphylococcus colonization in critically ill children." PLOS ONE 20, no. 1 (2025): e0316460. https://doi.org/10.1371/journal.pone.0316460.

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Background Surveillance cultures to identify patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) is recommended at pediatric intensive care unit (PICU) admission but doesn’t capture other methicillin-resistant Staphylococcus and is resource intensive. We determined the prevalence and identified nasal microbiome predictors for methicillin-resistant Staphylococcus colonization at the time of PICU admission. Study design A prospective cohort study was performed in a 20-bed pediatric intensive care unit (PICU) between 2020–2021. Anterior nares nasal swabs processed for MRSA

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Berikten, Derya, and Sukran Gunaydın. "Exploring natural antimicrobial properties: cell-free culture filtrates of Aspergillus niger and Rhizomucor pusillus." Biotech Studies 34, no. 2 (2025): 29–38. https://doi.org/10.38042/biotechstudies.1739583.

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Fungi are rich sources of medicinal bioactive metabolites. The fungi used in this study were identified as Rhizomucor pusillus and Aspergillus niger through multilocus gene sequencing. HPLC was used to analyze the cell-free culture filtrate (CFCF) of the fungi. The most prevalent organic acid in A. niger was tartaric acid, whereas the most predominant acid in R. pusillus was succinic acid. Furthermore, chlorogenic acid was the most abundant phenolic compound in both CFCFs. The impacts of the CFCFs as antibacterial agents against Gram (+) bacteria Staphylococcus aureus, Enterococcus faecalis, m

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Lokhande, Amita A., Manas K. Behera, and Sachin V. Wankhede. "White coat - is it safe?" International Journal of Contemporary Pediatrics 10, no. 1 (2022): 23. http://dx.doi.org/10.18203/2349-3291.ijcp20223415.

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Background: The transient contamination of medical professional’s attires including white coats is one of the major vehicles for the horizontal transmission of microorganisms in the hospital. In particular, white-coat cuffs had a higher bacterial load than the mouths of the pockets. The bacterial isolates were resistant to nearly all of the antibiotics tested. This study was conducted to determine the level and type of microbial contamination present on the white coats of medical students in order to assess the risk of transmission of pathogenic micro-organisms by this route in a hospital sett

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Ntambi, Saidi, Dwi Sutiningsih, Maiga Ayub Hussein, and Budi Laksono. "Distribution and Prevalence of Multidrug-Resistant Organisms (MDROs) Among MDRO-Positive Individuals at Dr. Kariadi Hospital." Jurnal Epidemiologi Kesehatan Komunitas 8, no. 2 (2023): 103–9. http://dx.doi.org/10.14710/jekk.v8i2.18530.

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Background: Multidrug-resistant organisms (MDRO) pose a significant challenge to healthcare facilities globally, impacting patient outcomes and healthcare costs. Understanding the distribution and prevalence of MDRO is crucial for effective infection control and prevention strategies. This study aimed to investigate the distribution and prevalence of MDROs, among MDRO-positive individuals at Dr. Kariadi Hospital.Methods: A retrospective analysis of secondary data was conducted, encompassing a diverse range of MDROs, including ESBL, carbapenem-resistant Enterobacteriaceae (CRE), methicillin-res

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Janardhan, KVB, P. Venkata Ramana, and Ch Suryamani. "PHENOTYPIC DETECTION OF INDUCIBLE CLINDAMYCIN RESISTANCE IN STAPHYLOCOCCUS SPECIES ISOLATED FROM CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL." International Journal of Advanced Research 11, no. 03 (2023): 178–83. http://dx.doi.org/10.21474/ijar01/16404.

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Introduction: Clindamycin is an effective drug used as an alternative to Vancomycin to treat skin and soft tissue infections caused by Staphylococcus spp. Reporting Staphylococcus as susceptible to Clindamycin without checking for inducible Clindamycin resistance may lead to therapeutic failure. Aim: To detect inducible Clindamycin resistance (MLSBi) among clinical isolates of Staphylococci by using a simple double-disc diffusion test (D-test). Methods: It was a prospective study conducted for 6 months from June 2022 to November 2022. All the Staphylococcal isolates from various samples were t

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Chaudhry, Priya, Anita Pandey, Priyanka Chaturvedi, and Km Sangita. "Molecular characterization of linezolid resistance in clinically significant isolates of coagulase negative Staphylococcus species, a hospital based study from Western Uttar Pradesh." Biomedicine 43, no. 3 (2023): 958–62. http://dx.doi.org/10.51248/.v43i3.2721.

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Introduction and aim: The emergence of Multidrug-resistant Coagulase-negative Staphylococcus species is a therapeutic problem. Linezolid-resistant CoNS (LRCoNS) are on a significant rise, with a global prevalence of around 2%. The acquisition of cfr (chloramphenicol-florfenicol resistance) gene is the commonest mechanism leading to resistance. This study aimed to determine the molecular characterization of linezolid resistance in clinically significant isolates of Coagulase Negative Staphylococci (CoNS). Material and Methods: The 1061 clinical isolates of CoNS were identified by standard bacte

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Chand, Ramesh, Yuvraj Sharma, and Ritu Rakholia. "Burden of central nervous system infection in cases of fever with seizure and its association with outcome: an experience in a tertiary care center of Uttarakhand, India." International Journal of Contemporary Pediatrics 6, no. 2 (2019): 683. http://dx.doi.org/10.18203/2349-3291.ijcp20190711.

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Background: CNS infections have been linked to adverse neurological sequelae notably seizures and mortality. Although, various etiologies of AFE have been studied, but the mystery still remains untangled for the substantial risk factors for the diagnosis and outcome.Methods: This prospective study was carried out on 67 children between 2 months to 15 years, from (May 2016 to April 2017) tertiary care centre of Uttarakhand. Patients were analysed for demographic variables, haematological parameters, CSF analysis, neuroimaging and their outcome was assessed at one month of follow up.Results: Thi

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Galler, Herbert, Josefa Luxner, Christian Petternel, et al. "Multiresistant Bacteria Isolated from Intestinal Faeces of Farm Animals in Austria." Antibiotics 10, no. 4 (2021): 466. http://dx.doi.org/10.3390/antibiotics10040466.

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In recent years, antibiotic-resistant bacteria with an impact on human health, such as extended spectrum β-lactamase (ESBL)-containing Enterobacteriaceae, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE), have become more common in food. This is due to the use of antibiotics in animal husbandry, which leads to the promotion of antibiotic resistance and thus also makes food a source of such resistant bacteria. Most studies dealing with this issue usually focus on the animals or processed food products to examine the antibiotic resistant bacteria. Thi

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