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1

Pavlík, M., M. Váňová, V. Laudová, and J. Harmatha. "Fungitoxicity of natural heterocycle glucoside vicine obtained from Vicia faba L. against selectedmicroscopic filamentous fungi." Plant, Soil and Environment 48, No. 12 (2011): 543–47. http://dx.doi.org/10.17221/4410-pse.

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Vicine and convicine were isolated from mature seeds of Vicia faba L. These compounds were separated from the relevant fractions by HPLC and identified by IR, MS and NMR. Obtained vicine was used for all bioassays. Vicine in concentration of 25 µg in 1 ml of medium had significant toxic effect. The concentration of 5 µg of vicine in 1 ml of medium had significant fungistatic effect for fungi Fusarium culmorum and Alternaria alternata. The concentration of 500 ng of vicine in 1 ml of medium had significant fungistatic effect for fungi Cladosporium herbarum and Botrytis ciner
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2

Li, Jianbo, Yue Jin, Huiyan Fu, Yihui Huang, Xianqin Wang, and Yunfang Zhou. "Pharmacokinetics and bioavailability of gelsenicine in mice by UPLC–MS/MS." Biomedical Chromatography 33, no. 3 (2018): e4418. http://dx.doi.org/10.1002/bmc.4418.

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3

Niu, Kai, Huiyu Yan, Chunjie Guo, Sixi Zhang, Wei Zhu, and Shiyong Teng. "Pharmacokinetics and tissue distribution of oroxin B in rats using a validated LC–MS/MS assay." Biomedical Chromatography 33, no. 3 (2018): e4417. http://dx.doi.org/10.1002/bmc.4417.

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4

Herdis, Herdis, I. Wayan Angga Darmawan, and Muhammad Rizal. "PENAMBAHAN BEBERAPA JENIS GULA DAPAT MENINGKATKAN KUALITAS SPERMATOZOA BEKU ASAL EPIDIDIMIS TERNAK DOMBA (Addition of Various Sugars in Improving Quality of Frozen Thawed Epididymal Spermatozoa of Ram)." Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences 10, no. 2 (2016): 200–204. http://dx.doi.org/10.21157/j.ked.hewan.v10i2.5139.

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ABSTRACT The purpose of this research was to examine the effect of various sugars addition in Tris extender on quality of frozen thawed epididymal spermatozoa of ram. Collected spermatozoa was divided into five tubes and centrifuged at 3,000 rpm for 30 minutes. Supernatants were removed and pellets were diluted with Tris extender (control), Tris extender + 0.4% dextrose (dextrose), Tris extender + 0.4% maltose (maltose), Tris extender + 0.4% lactose (lactose), and Tris extender + 0.4% sucrose (sucrose), respectively. There were no significantly difference among treatment on mean percentages of
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5

Zhang, Xiaoran, Nan Guo, Wei Ji, and Qing Wen. "Rapid quantitative analysis of etoricoxib in human plasma by UPLC-MS/MS and application to a pharmacokinetic study in Chinese healthy volunteers." Biomedical Chromatography 33, no. 2 (2018): e4414. http://dx.doi.org/10.1002/bmc.4414.

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Lu, Pengfei, Yong Chen, Manliang Tan, and Yongjiang Wu. "Chemical profiling by LC-MS/MS and HPLC fingerprint combined with chemometrics and simultaneous determination of 16 characteristic ingredients for the quality consistency evaluation of Shaoyao-Gancao Decoction." Biomedical Chromatography 33, no. 2 (2018): e4401. http://dx.doi.org/10.1002/bmc.4401.

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7

Fujianto, Slamet, Sugiyanto Sugiyanto, and Mohamad Irwan Katili. "Analisis Variasi Nilai Time Repetition (TR) dan Time Inversion (TI) terhadap Informasi Anatomi Sekuens Turbo Inversion Recovery Magnitude (TIRM) MRI Wrist Joint Dengan Menggunakan MRI 0,3 Tesla." Jurnal Imejing Diagnostik (JImeD) 2, no. 1 (2016): 97–102. http://dx.doi.org/10.31983/jimed.v2i1.3164.

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Backgroud: The Turbo Inversion Recovery Magnitude (TIRM) pulse sequence is used to examine wrist joint, especially in the coronal plane. Main parameters of inversion recovery pulse sequence are time repetition (TR), time echo (TE) and time inversion (TI). This study aims to analyze the variation of time repetition (TR) and time inversion (TI) on anatomical information using TIRM pulse sequence on wrist joint MR imaging with 0,3 tesla.Methods: This study was a quantitave experimental study with a linear regression test. This study was conducted in Radiology Department of Banyumas hospital using
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8

Ferreiro-Vera, Carlos, José María Mata-Granados, Feliciano Priego-Capote, José Manuel Quesada-Gómez, and María Dolores Luque de Castro. "Automated targeting analysis of eicosanoid inflammation biomarkers in human serum and in the exometabolome of stem cells by SPE–LC–MS/MS." Analytical and Bioanalytical Chemistry 399, no. 3 (2010): 1093–103. http://dx.doi.org/10.1007/s00216-010-4400-6.

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9

Goh, T. B., M. M. Mordi та S. M. Mansor. "Mass Spectrometry (LC-MS-MS) As a Tool in the Maillard Reaction Optimisation and Characterisation of New 6-methoxy-tetrahydro-β-carboline Derivatives". Sains Malaysiana 44, № 1 (2015): 127–37. http://dx.doi.org/10.17576/jsm-2015-4401-18.

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10

Šćepanović, Darija, Tina Klavs, Ivan Verdenik, and Čedomir Oblak. "The Prevalence of Musculoskeletal Pain of Dental Workers Employed in Slovenia." Workplace Health & Safety 67, no. 9 (2019): 461–69. http://dx.doi.org/10.1177/2165079919848137.

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Work-related musculoskeletal (MS) disorders are considered one of the most frequent occupational diseases among dental workers. Dental work consists of static, demanding tasks that involve repeated gripping of small-sized instruments. The purpose of this study was to investigate the prevalence of MS pain, the areas of pain, and the risk factors for MS pain in dental workers. A self-administrated questionnaire was used as a data collection instrument for dental workers who voluntarily responded to the invitation. To determine the prevalence and severity location of MS pain, the Cornell Musculos
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11

Nortvedt, M. W., T. Riise, K.-M. Myhr, A.-M. Landtblom, A. Bakke, and H. I. Nyland. "Reduced quality of life among multiple sclerosis patients with sexual disturbance and bladder dysfunction." Multiple Sclerosis Journal 7, no. 4 (2001): 231–35. http://dx.doi.org/10.1177/135245850100700404.

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Objective: Physical disability explains only part of the reduced quality of life found among multiple sclerosis (MS) patients. Bladder dysfunction and sexual disturbance are frequent and distressing problems for MS patients. We therefore estimated the relationship between the presence and degree of sexual disturbance/bladder dysfunction and the patients' quality of life as measured by the SF-36 Health Survey. Methods: We performed a cross-sectional study of all individuals with the onset of MS between 1976 and 1986 in Hordaland County, Norway. The disease duration at examination was 9-19 years
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12

Sun, Li-Ming, Bo Zhang, Yu-Chen Wang, Hao-Ke He, Xiao-Guang Chen, and Su-Juan Wang. "Metabolomic analysis of raw Pinelliae Rhizoma and its alum-processed products via UPLC-MS and their cytotoxicity." Biomedical Chromatography 33, no. 2 (2018): e4411. http://dx.doi.org/10.1002/bmc.4411.

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13

Dekkiche, Malika. "Crossing the line: Mamluk response to Qaramanid threat in the fifteenth century according to MS ar. 4440 (BnF, Paris)." Bulletin of the School of Oriental and African Studies 80, no. 2 (2017): 253–81. http://dx.doi.org/10.1017/s0041977x17000453.

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AbstractThe present article investigates the complex dynamics of the relationship between the Mamluk sultans and Qaramanid rulers in the second half of the fifteenth century. Based on the revealing of an unpublished corpus of letters (MS ar. 4440, BnF, Paris), which preserved copies of the correspondence exchanged between sultan Īnāl and Ibrāhīm II after the Qaramanids' Rebellion in 860–862/1456–58 and their capture of the Mamluk fortresses in Tarsus and Gülek. After briefly sketching the history of their contact and alliances, I then concentrate on the Qaramanid Rebellion itself, presenting t
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14

Vilariño, Maria, F. Rudeaux, Alicia León, and Michel Picard. "Teneur en énergie métabolisable et digestibilité des acides aminés chez le coq de deux sous-produits de l'extraction de l'huile : tourteau de palmiste pressé (Elaeis guineensis) et germe et son de maïs extrait (Zea mays)." Revue d’élevage et de médecine vétérinaire des pays tropicaux 49, no. 3 (1996): 229–34. http://dx.doi.org/10.19182/remvt.9519.

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La digestibilité d'un échantillon de tourteau de palmiste vénézuélien (TP) [contenant 92,2 % de matière sèche (MS) et en pourcentage de MS : 13,5 de protéine brute (PB), 14,6 de matières grasses (MG), 4,6 de matières minérales (MM), 60,7 de parois végétales (PAR) et moins de 1 % d'amidon et de sucres] est mesurée chez neuf coqs nourris ad libitum (30 p. 100 TP + 67 % maïs témoin + 3 % prémélange). La valeur d'énergie métabolisable apparente (EMA) de TP est 1 963 ± 52 kcal/kg MS. La digestibilité vraie moyenne des acides aminés de TP est 48 % (pour la lysine, 26 %). Les mêmes mesures sont faite
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15

Hategeka, Celestin, Anthony L. Traboulsee, Katrina McMullen, and Larry D. Lynd. "Association of Unemployment and Informal Care with Stigma in Multiple Sclerosis." International Journal of MS Care 21, no. 5 (2019): 214–25. http://dx.doi.org/10.7224/1537-2073.2017-108.

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Abstract Background: Multiple sclerosis (MS) typically affects young adults during their primary productive years. We assessed the magnitude of, and factors associated with, employment status and informal care in people with MS in Canada. Methods: Data were compiled from the nationally representative cross-sectional Survey on Living with Neurological Conditions in Canada (SLNCC), which included adolescents and adults (age ≥15 years). Employment status was categorized as currently working or not working. The frequency of informal care that people with MS received was categorized as none, less t
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16

Dekkiche, Malika. "The Letter and Its Response: The Exchanges between the Qara Qoyunlu and the Mamluk Sultan: ms Arabe 4440 (BnF, Paris)." Arabica 63, no. 6 (2016): 579–626. http://dx.doi.org/10.1163/15700585-12341413.

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In their manuals, chancery scribes often discussed the differences between initial letters (ibtidāʾ) and their responses (ǧawāb), yet one question persists: which one was of higher status? Basing their reflections on literary criteria, secretaries were divided. Most of them granted the response more value, since it required greater skill and literary dexterity from its author. While the mubtadiʾ had the entire choice of terms, structure, and prolixity, the muǧīb was challenged by the letter’s wording. Others, however, considered both tasks equal in difficulty, since all secretaries were requir
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17

Gurčinienė, Ona, and Alvydas Šoliūnas. "SIMETRIJOS ĮTAKA SKIRTINGO SUDĖTINGUMO FIGŪRŲ ATPAŽINIMUI." Psichologija 23 (January 1, 2001): 102–10. http://dx.doi.org/10.15388/psichol.2001..4416.

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Psichofizikiniame eksperimente su žmogumi tirta simetrijos įtaka skirtingo elementų skaičiaus figūroms atpažinti maskavimo, t. y. analizės laiko trūkumo, sąlygomis. Sunkiai verbalizuojamos testo figūros skyrėsi vertikalių ir horizontalių linijų skaičiumi ir simetrijos rodikliu. Testo figūrų rinkinius sudarė po lygiai simetrinių ir nesimetrinių figūrų, turinčių 4, 6 arba 8 linijos atkarpas. Stimulai buvo pateikiami šitokia tvarka: garsinis signalas, testo figūra (10 ms), tarpstimulinis intervalas, maskuojantis vaizdas, kurio pagrindu sudarytos testo figūros (500 ms). Tarpstimulinis intervalas p
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18

Lipp, Ottmar V., David L. Neumann, David A. T. Siddle, and Patricia J. Dall. "Assessing the Effects of Attention and Emotion on Startle Eyeblink Modulation." Journal of Psychophysiology 15, no. 3 (2001): 173–82. http://dx.doi.org/10.1027//0269-8803.15.3.173.

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Abstract Two experiments were conducted to assess simultaneously the effects of attentional and emotional processes on startle eyeblink modulation. In each experiment, participants were presented with a pleasant and an unpleasant picture. Half the participants were asked to attend to the pleasant picture and to ignore the unpleasant picture, whereas the reverse was the case for the other participants. Startle probes were presented at 3500 and 4500 ms after stimulus onset in Experiment 1 and at 250, 750, and 4450 ms after stimulus onset and 950 ms after stimulus offset in Experiment 2. Attentio
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19

Silva, G. N. S., T. B. Spader, S. H. Alves, C. A. Mallmann, and B. M. Heinzmann. "Composition and evaluation of the antimicrobial activity of the essential oil of Senecio selloi Spreng DC." Revista Brasileira de Plantas Medicinais 15, no. 4 (2013): 503–7. http://dx.doi.org/10.1590/s1516-05722013000400005.

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The essential oil of the aerial parts of Senecio selloi Spreng. DC. was extracted by hydrodistillation and analyzed by GC/MS. Nineteen compounds were identified, representing 99.9% of the total. The main compounds were found to be sesquiterpene hydrocarbons (71.3%), most of them with a bisabolane skeleton (59.4%). The major constituent was α-zingiberene (54%), followed by monoterpene α-isolimonene (16%). The essential oil was also tested against two Gram-positive and two Gram-negative bacterial species, three yeasts, and an algae. From the strains assayed, only Bacillus subtilis ATCC 6633 show
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20

Нишанбаев (Nishanbaev), Сабир (Sabir) Зарипбаевич (Zaripbaevich), Хайрулла (Khairulla) Мамадиевич (Mamadievich) Бобакулов (Bobakulov), Баходир (Bakhodir) Сотволдиевич (Sotvoldievich) Охундедаев (Okhundedaev), Собирджан (Sobirjan) Анарматович (Anarmatovich) Сасмаков (Sasmakov), Насрулла (Nasrullah) Джалилович (Dzhalilovich) Абдуллаев (Abdullayev), and Салимахон (Salimahon) Фазиловна (Fazilovna) Арипова (Aripova). "COMPONENT COMPOSITION OF THE EXTRACTS AND ESSENTIAL OILS FROM THE ALHAGI PERSARUM, GROWING IN UZBEKISTAN AND THEIR ANTIMICROBIAL ACTIVITY." chemistry of plant raw material, no. 4 (May 23, 2018): 125–32. http://dx.doi.org/10.14258/jcprm.2018043804.

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The volatile compounds of hexane and benzene extracts were studied by GC-MS analysis, as well as were investigated the composition of essential oils obtained by steam and hydrodistillation from the aerial part of Alhagi persarum Boiss. & Buhse, collected during the flowering period in the Fergana region of the Republic of Uzbekistan.
 As a result of the studies, 44 components were found in the hexane and benzene extracts, among them the neophytadiene (44.0%), hexahydrofarnesyl acetone (20.5%), phytol (17.1%), dihydroactinidiolide (2.0%), a-thujone (32.1%) and b-thujone (9.8%), camphor
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Nunes, Ricardo Vianna, Horacio Santiago Rostagno, Luiz Fernando Teixeira Albino, Paulo Cezar Gomes, and Rodrigo Santana Toledo. "Composição bromatológica, energia metabolizável e equações de predição da energia do grão e de subprodutos do trigo para pintos de corte." Revista Brasileira de Zootecnia 30, no. 3 (2001): 785–93. http://dx.doi.org/10.1590/s1516-35982001000300025.

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Foram determinados os valores de energia metabolizável aparente (EMA) e energia metabolizável aparente corrigida pelo balanço de nitrogênio (EMAn) e elaboradas equações de predição dos valores energéticos, utilizando a composição química de 11 alimentos. Os alimentos avaliados foram: farinha morena, farinha de trigo, trigo-grão, triguilho, gérmen de trigo, resíduo de biscoito, resíduo de macarrão e quatro farelos de trigo. Foi utilizado o método tradicional de coleta total de excretas, com 480 pintos de corte, de 16 a 24 dias de idade. O delineamento experimental foi o inteiramente casualizado
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22

Fjeldstad, Cecilie, Gabriel Pardo, and Michael Bemben. "Quality of Life According to Duration of Disease in Women With Low Disability in Multiple Sclerosis." International Journal of MS Care 10, no. 3 (2008): 77–80. http://dx.doi.org/10.7224/1537-2073-10.3.77.

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The primary aim of this study was to investigate the relationship between Expanded Disability Status Scale (EDSS) scores and quality of life (QOL) in women with multiple sclerosis (MS) and low disability and whether duration of disease influenced the established relationship. Sixty-six women diagnosed with MS (44.0 ± 1.2 [standard error] years) had EDSS scores of <5.0 as determined by their neurologist. Duration of disease from time of diagnosis ranged from 2 months to 28 years, and subjects were arbitrarily divided into three groups (group 1: 0.1–10.0 years; group 2: 10.1–20.0 years; g
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23

Bouschen, Werner, Oliver Schulz, Daniel Eikel, and Bernhard Spengler. "Matrix vapor deposition/recrystallization and dedicated spray preparation for high-resolution scanning microprobe matrix-assisted laser desorption/ionization imaging mass spectrometry (SMALDI-MS) of tissue and single cells." Rapid Communications in Mass Spectrometry 24, no. 3 (2010): 355–64. http://dx.doi.org/10.1002/rcm.4401.

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24

Molla, M. M. H., K. M. Nasiruddin, M. Al-Amin, M. S. Haque, and D. Khanam. "IN VITRO REGENERATION OF POTATO (Solanum tuberosum L.)." Bangladesh Journal of Plant Breeding and Genetics 24, no. 1 (2011): 07–14. http://dx.doi.org/10.3329/bjpbg.v24i1.16308.

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The experiment was conducted during the period from January to December, 2008 at the Laboratory of Biotechnology, Bangladesh Agricultural Research Institute, Gazipur, Bangladesh. A two step procedure was followed for direct plant regeneration of potato. Murashige and Skoog (MS) basal medium supplemented with 0.5 mg l-1 IBA and 30 g sugar was used for in vitro potato plants development via nodal cuttings. Leaves and internodes of in vitro grown potato variety Asterix was cultured in instant MS basal medium supplemented with 0.01 mg l-1 IAA, 0.20 mg l-1 GA3, 44.0 g l-1 CaCl2, 20 g sucrose. Eight
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Kamada, Takashi, Chin-Soon Phan, Tatsufumi Okino, and Charles Santhanaraju Vairappan. "Cytotoxicity and Antibacterial Potential of Halogenated Chamigrenes from Malaysian Red Alga, Laurencia majuscula." Planta Medica International Open 6, no. 02 (2019): e36-e40. http://dx.doi.org/10.1055/a-0977-4418.

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AbstractRed algae of the genus Laurencia have been known to produce a wide array of bioactive secondary metabolites. Here, we report the isolation of two new halogenated chamigrenes, lauremantanones A (1) and B (2), along with seven known compounds, dendroidiol (3), (+)-elatol (4), cartilagineol (5), obtusol (6), (+)-laurencenone B (7), 2-chloro-3-hydroxy-α-chamigren-9-one (8), and puertitol A (9), from a population of Laurencia majuscula (Harvey) Lucas from Mantanani Island (North Borneo). The structures of the two new metabolites were determined based on spectroscopic data (IR, 1D and 2D NMR
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26

Ricaurte, Basma M., and Harris C. Taylor. "Abstract #247: Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) and Hypothermia in Multiple Sclerosis (MS)." Endocrine Practice 12 (March 2006): 91–92. http://dx.doi.org/10.1016/s1530-891x(20)44010-8.

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27

Manihuruk, Dian Sri Bintang Hasiholan, Darwin Darwin, and Agus Arip Munawar. "Penentuan Kualitas Buah Jeruk (Citrus Sinensis L) Menggunakan Teknologi Laser Photo-Acoustics (LPAS) Dengan Metode Support Vector Machine (SVM)." Jurnal Ilmiah Mahasiswa Pertanian 4, no. 2 (2019): 377–86. http://dx.doi.org/10.17969/jimfp.v4i2.10945.

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Abstrak. Penelitian ini bertujuan untuk mengetahui kandungan vitamin C dan kadar gula pada buah jeruk dengan menggunakan teknologi Laser Photo Acoustics. Penelitian ini menggunakan sampel buah jeruk manis sebanyak 20 buah dengan empat indeks yaitu indeks pertama tidak matang (TM), setengah matang (SM), matang (M) dan matang sekali (MS). Hasil penelitian menunjukan bahwa panjang gelombang yang diperoleh dalam menduga kadar vitamin C dan kadar gula dikisaran 4418 cm-1 - 4595 cm-1. Selanjutnya prediksi kadar gula terbaik mendapatkan (R2) sebesar 0.769, (r) sebesar 0.877, RMSEC 0.803 sedangkan RPD
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28

Pollington, Anthony D., William S. Kinman, Susan K. Hanson, and Robert E. Steiner. "Polyatomic interferences on high precision uranium isotope ratio measurements by MC-ICP-MS: applications to environmental sampling for nuclear safeguards." Journal of Radioanalytical and Nuclear Chemistry 307, no. 3 (2015): 2109–15. http://dx.doi.org/10.1007/s10967-015-4419-4.

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Cabreira, Verónica, Pedro Abreu, Ricardo Soares-dos-Reis, Joana Guimarães, and Maria José Sá. "Multiple Sclerosis, Disease-Modifying Therapies and COVID-19: A Systematic Review on Immune Response and Vaccination Recommendations." Vaccines 9, no. 7 (2021): 773. http://dx.doi.org/10.3390/vaccines9070773.

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Understanding the risks of COVID-19 in patients with Multiple Sclerosis (MS) receiving disease-modifying therapies (DMTs) and their immune reactions is vital to analyze vaccine response dynamics. A systematic review on COVID-19 course and outcomes in patients receiving different DMTs was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Emerging data on SARS-CoV-2 vaccines was used to elaborate recommendations. Data from 4417 patients suggest that MS per se do not portend a higher risk of severe COVID-19. As for the general population, adv
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30

Zurawski, Jonathan, Shahamat Tauhid, Renxin Chu, et al. "7T MRI cerebral leptomeningeal enhancement is common in relapsing-remitting multiple sclerosis and is associated with cortical and thalamic lesions." Multiple Sclerosis Journal 26, no. 2 (2019): 177–87. http://dx.doi.org/10.1177/1352458519885106.

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Background: Meningeal inflammation may contribute to gray matter (GM) involvement in multiple sclerosis (MS) and is proposed to manifest as magnetic resonance imaging (MRI) leptomeningeal enhancement (LME). Objective: To investigate how LME relates to GM lesions in relapsing-remitting multiple sclerosis (RRMS) at 7T. Methods: A total of 30 RRMS subjects (age (mean ± standard deviation (SD)): 44.0 ± 11.3 years, 93% on disease-modifying treatment) and 15 controls underwent gadolinium-enhanced three-dimensional (3D) MP2RAGE (magnetization-prepared 2 rapid gradient-echo) and fluid-attenuated inver
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KLAOCHEED, Sutha, Suphat RITTIRAT, Kanchit THAMMASIRI, and Somporn PRASERTSONGSKUN. "Alginate-encapsulation, Short-term Storage and Plantlet Regeneration from Encapsulated Protocorm-like Bodies (PLBs) of Cymbidium finlaysonianum Lindl.: An Endangered Orchid of Thailand." Walailak Journal of Science and Technology (WJST) 15, no. 10 (2017): 725–37. http://dx.doi.org/10.48048/wjst.2018.3325.

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Synthetic seed technology is becoming popular due to its wide application in germplasm conservation and for exchanges among countries in the floriculture trade. This method was used to study the bead formations and the conversion capabilities of Cymbidium finlaysonianum Lindl. For artificial seeds, new protocorm-like bodies (PLBs) (about 4 - 5 mm in diameter) of Cymbidium finlaysonianum Lindl. were isolated individually from 2-month-old proliferating PLB-clusters cultured in Vacin and Went (VW) liquid medium supplemented with 8.84 µM 6-benzyl-aminopurine (BAP). Different concentrations of sodi
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Lecona-Guzmán, Carlos Alberto, Sheila Reyes-Zambrano, Felipe Alonso Barredo-Pool, et al. "In Vitro Propagation of Agave americana by Indirect Organogenesis." HortScience 52, no. 7 (2017): 996–99. http://dx.doi.org/10.21273/hortsci10498-16.

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Factors such as slow growth, low rates of sexual and asexual reproduction, and viability of seeds among others limit the massive propagation of Agave americana L. by conventional methods. In this study, callus induction and shoot proliferation was determined in A. americana using Murashige and Skoog (MS) medium supplemented with dicholorophenoxyacetic acid (2,4-D) and 6-benzyl adenine (BA). Meristematic tissue was used as the explants, and were placed on MS medium supplemented with 30.0 g·L−1 sucrose with 0.11, 0.18, or 0.45 μm 2,4-D and 11.0, 22.0, 38.2, 44.0, 58.7, or 73.3 μm BA. Treatments
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Croteau, David, Scott Letendre, Brookie M. Best, et al. "Therapeutic Amprenavir Concentrations in Cerebrospinal Fluid." Antimicrobial Agents and Chemotherapy 56, no. 4 (2012): 1985–89. http://dx.doi.org/10.1128/aac.05098-11.

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ABSTRACTAntiretrovirals that reach higher concentrations in cerebrospinal fluid (CSF) are associated with better control of HIV in CSF and possibly better neurocognitive performance. The objective of this study was to determine whether amprenavir (APV) concentrations in CSF are in the therapeutic range. Individuals were selected based on the use of regimens that included fosamprenavir (FPV), a prodrug of APV, and the availability of stored CSF and matched plasma. Total APV was measured in 119 matched CSF-plasma pairs from 75 subjects by high-performance liquid chromatography (HPLC) (plasma) or
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Holkeri, Arttu, Antti Eranti, M. Anette E. Haukilahti, et al. "Predicting sudden cardiac death in a general population using an electrocardiographic risk score." Heart 106, no. 6 (2019): 427–33. http://dx.doi.org/10.1136/heartjnl-2019-315437.

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ObjectiveWe investigated whether combining several ECG abnormalities would identify general population subjects with a high sudden cardiac death (SCD) risk.MethodsIn a sample of 6830 participants (mean age 51.2±13.9 years; 45.5% male) in the Mini-Finland Health Survey, a general population cohort representative of the Finnish adults aged ≥30 years conducted in 1978–1980, we examined their ECGs, following subjects for 24.3±10.4 years. We analysed the association between individual ECG abnormalities and 10-year SCD risk and developed a risk score using five ECG abnormalities independently associ
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Tovee, M. J., E. T. Rolls, A. Treves, and R. P. Bellis. "Information encoding and the responses of single neurons in the primate temporal visual cortex." Journal of Neurophysiology 70, no. 2 (1993): 640–54. http://dx.doi.org/10.1152/jn.1993.70.2.640.

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1. The possibility of temporal encoding in the spike trains of single neurons recorded in the temporal lobe visual cortical areas of rhesus macaques was analyzed with the use of principal component and information theory analyses of smoothed spike trains. The neurons analyzed had responses selective for faces. 2. Provided that a correction was applied to earlier methods of principal component analysis used for neuronal spike trains, it was shown that the first principal component provides by a great extent the most information, with the second and third adding only small proportions (on averag
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36

Park, Dong-Uk, Jihoon Park, Kee Won Yang, Ju-Hyun Park, Jung-Hwan Kwon, and Han Bin Oh. "Properties of Polyhexamethylene Guanidine (PHMG) Associated with Fatal Lung Injury in Korea." Molecules 25, no. 14 (2020): 3301. http://dx.doi.org/10.3390/molecules25143301.

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The use of humidifier disinfectant (HD) has been determined to be associated with lung injuries (HDLI) in Korea. Although HD brands containing polyhexamethylene guanidine (PHMG) oligomers have been found to cause more HDLI compared to brands containing other disinfectants, the physicochemical properties of PHMG have been poorly defined. We aimed to quantify the PHMG dissolved in HD brands, characterize the number-average (Mn) and weight-average (Mw) molecular masses, and identify the polymerization degree of PHMG. Analysis of the PHMG oligomers was performed using a matrix-assisted laser desor
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37

Mirjalili, Mohammad, Peyman Salehi, Ali Sonboli, Javad Hadian, Samad Ebrahimi, and Morteza Yousefzadi. "The composition and antibacterial activity of the essential oil of Levisticum officinale Koch. flowers and fruits at different developmental stages." Journal of the Serbian Chemical Society 75, no. 12 (2010): 1661–69. http://dx.doi.org/10.2298/jsc100524126m.

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The composition and antibacterial activity of the essential oil of Levisticum officinale Koch. at different developmental stages (flower, immature fruit, green mature fruit and ripened fruit) is reported. The essential oils were obtained by hydrodistillation of air-dried samples and their antibacterial activities were tested against seven bacteria. The yield of oil (w/w %) in different stages was in the order: immature fruit (1.5 %) > green mature fruit (1.0 %) > ripened fruit (0.6 %) > flower (0.1 %). The essential oils were analyzed by GC and GC-MS. In total, 27, 31, 28 and 26 const
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38

Wood, John C., Barinder P. Kang, Alexis Thompson, et al. "The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores." Blood 116, no. 4 (2010): 537–43. http://dx.doi.org/10.1182/blood-2009-11-250308.

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AbstractWe present results from a prospective, multicenter, open-label, single-arm study evaluating response of cardiac and liver iron to deferasirox therapy for 18 months. Twenty-eight patients with abnormal T2* and normal left ventricular ejection fraction were enrolled from 4 US centers. All patients initially received deferasirox doses of 30 to 40 mg/kg per day. Patients were severely iron overloaded: mean liver iron concentration (LIC) 20.3 mg Fe/g dry weight, serum ferritin 4417 ng/mL, and cardiac T2* 8.6 ms. In the intent-to-treat population, 48% reached the primary endpoint (cardiac T2
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39

Yaroslavskaya, E. I., D. V. Krinochkin, I. R. Krinochkina, et al. "Comparison of cardiovascular and psychological profile of young military men after COVID-19 with and without pneumonia." Russian Journal of Cardiology 26, no. 2 (2021): 4321. http://dx.doi.org/10.15829/1560-4071-2021-4321.

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Aim. To compare the cardiovascular and psychological profile of young military population after coronavirus disease 2019 (COVID-19) with/without pneumonia.Material and methods. We examined 26 military men under 30 years of age (22,3±3,7 years/21,0 [19,8; 24,3] years) with documented COVID 19 (3 months±2 weeks after two virus-negative polymerase chain reaction tests). The participants were divided into 2 groups: experimental group (n=16) — those with COVID-19 pneumonia; comparison group (n=10) — those without pneumonia. All subjects underwent a complex of clinical and diagnostic tests.Results.
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40

Hill, Craig, Vincent S. Neary, Michele Guala, and Fotis Sotiropoulos. "Performance and Wake Characterization of a Model Hydrokinetic Turbine: The Reference Model 1 (RM1) Dual Rotor Tidal Energy Converter." Energies 13, no. 19 (2020): 5145. http://dx.doi.org/10.3390/en13195145.

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The mechanical power and wake flow field of a 1:40 scale model of the US Department of Energy’s Reference Model 1 (RM1) dual rotor tidal energy converter are characterized in an open-channel flume to evaluate power performance and wake flow recovery. The NACA-63(4)-24 hydrofoil profile in the original RM1 design is replaced with a NACA-4415 profile to minimize the Reynolds dependency of lift and drag characteristics at the test chord Reynolds number. Precise blade angular position and torque measurements were synchronized with three acoustic Doppler velocimeters (ADV) aligned with each rotor c
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Cancado, Rodolfo, Maria Cristina Olivato, Paula Bruniera, Murilo Rezende Melo, and Carlos Chiattone. "Deferasirox for the Treatment of Transfusional Iron Overload In Sickle Cell Anemia: a 2-Yr Prospective Study." Blood 116, no. 21 (2010): 5148. http://dx.doi.org/10.1182/blood.v116.21.5148.5148.

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Abstract Abstract 5148 Background: Majority of patients with sickle cell disease receive repeated blood transfusions by adulthood. Because the body has no physiological mechanism to actively excrete excess iron, chelation therapy is important for the management of iron overload and its complications, including iron deposition into the liver, heart and endocrine organs, eventual death. Deferasirox (DFX) is a once-daily, oral iron chelator that is approved as first-line treatment of chronic transfusional iron overload. Its safety, tolerability and efficacy in reducing body iron burden have been
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42

Hai, Doan Ngoc, Lo Van Tung, Duong Khanh Van, et al. "Lead Environmental Pollution and Childhood Lead Poisoning at Ban Thi Commune, Bac Kan Province, Vietnam." BioMed Research International 2018 (November 18, 2018): 1–7. http://dx.doi.org/10.1155/2018/5156812.

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Lead poisoning is a public health problem in many areas of the world. Children are at particularly high risk for adverse effects of lead exposure; even at low concentrations, lead can affect physical, mental, and behavioral development. Children living near lead-zinc mines are at high risk for environmental lead poisoning, especially the contaminated soil. We conducted a cross-sectional descriptive study in Ban Thi Commune, northern Vietnam. 195 children (92,9% participation) aged 3-14 years old (average: 7.69 ± 2.90) were randomly selected from a list of all children prepared by the village h
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43

Ariyanto, Ariyanto, and Alamsyah Noor Ahmad. "Studi Analisis Perencanaan Peningkatan Ruas Jalan Mantingan-Ngabul / Jalan Sultan Hadlirin." Jurnal Disprotek 11, no. 2 (2020): 109–17. http://dx.doi.org/10.34001/jdpt.v11i2.1353.

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The development of roads in the City of Jepara continues to increase and the width of the road is insufficient to accommodate the traffic capacity causing flow obstruction and the road has an existing structural decline, causing the sections to be bumpy and potholes. It is necessary to do an analysis study on the improvement of the Mantingan-Ngabul road / Sultan Hadlirin road, Jepara Regency in order to solve this problem. From the analysis results obtained as follows: The ideal road widening for this road is at least 6 m. The analysis for calculating the pavement thickness index (ITP) for a 2
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44

Garzoli, Stefania, Valentina Laghezza Masci, Valentina Caradonna, Antonio Tiezzi, Pierluigi Giacomello, and Elisa Ovidi. "Liquid and Vapor Phase of Four Conifer-Derived Essential Oils: Comparison of Chemical Compositions and Antimicrobial and Antioxidant Properties." Pharmaceuticals 14, no. 2 (2021): 134. http://dx.doi.org/10.3390/ph14020134.

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In this study, the chemical composition of the vapor and liquid phase of Pinus cembra L., Pinus mugo Turra, Picea abies L., and Abies Alba M. needles essential oils (EOs) was investigated by Headspace-Gas Chromatography/Mass Spectrometry (HS-GC/MS). In the examined EOs, a total of twenty-eight components were identified, most of which belong to the monoterpenes family. α-Pinene (16.6–44.0%), β-pinene (7.5–44.7%), limonene (9.5–32.5%), and γ-terpinene (0.3–19.7%) were the most abundant components of the liquid phase. Such major compounds were also detected in the vapor phase of all EOs, and α-p
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45

Sözeri, B., F. Demir, S. Kalin, and C. Hasbal Akkuş. "POS0049 SARS-COV-2 INFECTION IN CHILDREN WITH RHEUMATIC DISEASE: EXPERIENCE OF A TERTIARY REFERRAL CENTER." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 229.1–230. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1164.

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Background:Patients with rheumatic diseases are considered at risk for serious infections due to their immune-compromised-status set in their primary systemic disease and the usage of immune-modulating therapies. Although various results have been reported on the subject, it is still unknown whether patients with rheumatic disease, many of whom are on immune-suppression, are at higher risk of severe COVID-19.Objectives:We aim to share our clinical SARS-CoV-2 experience in patient with the childhood rheumatic disease during pandemic.Methods:We evaluated 4470 patients at our pediatric-rheumatolo
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46

Lob, Sibylle, Krystyna Kazmierczak, Wei-Ting Chen, et al. "1588. Activity of Imipenem/Relebactam Against Clinical Isolates of P. aeruginosa and K. pneumoniae Collected in Asia/Pacific Countries – SMART 2016-2018." Open Forum Infectious Diseases 7, Supplement_1 (2020): S791. http://dx.doi.org/10.1093/ofid/ofaa439.1768.

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Abstract Background Relebactam (REL) inhibits class A and C β-lactamases and was approved in the USA in combination with imipenem (IMI) and cilastatin for the treatment of complicated intraabdominal and urinary tract infections. We evaluated the activity of IMI/REL against clinical isolates collected in Asia/Pacific as part of the global SMART surveillance program. Methods In 2016-2018, 56 clinical laboratories each collected up to 250 consecutive, aerobic and facultative gram-negative pathogens from various infection sources per year. Susceptibility was determined using CLSI broth microdiluti
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47

Simara, Pavel, Stanislav Stejskal, Irena Koutna, et al. "Apoptosis in Chronic Myeloid Leukemia Cells Transiently Treated with Imatinib or Dasatinib Is Caused by Residual BCR-ABL Kinase Inhibition." Blood 120, no. 21 (2012): 1668. http://dx.doi.org/10.1182/blood.v120.21.1668.1668.

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Abstract Abstract 1668 Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hemopoietic stem cells. The constitutively active tyrosine kinase BCR-ABL causes defects in the proliferation and differentiation of blood cells. CML is currently treated with tyrosine kinase specific inhibitors (TKIs), such as imatinib, nilotinib, and dasatinib. Transient, potent BCR-ABL inhibition with TKIs was demonstrated to commit CML cells to apoptosis irreversibly (Shah et al., Cancer Cell, 2008; Snead et al., Blood., 2009; Hiwase et al., Leukemia, 2009). This mechanism would explain the cli
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48

Amari, John V., Qi Lu, Mark Slein, and Robert Peters. "Pre-Clinical Characterization and Analysis of Long Lasting Recombinant Factor IXFc." Blood 116, no. 21 (2010): 4415. http://dx.doi.org/10.1182/blood.v116.21.4415.4415.

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Abstract Abstract 4415 A recombinant Factor IXFc fusion molecule has been demonstrated to prolong half-life in several species (normal mice, rats, monkeys and FIX-deficient mice and dogs). The recombinant fusion molecule consists of a single rFIX moiety fused to the Fc region of Immunoglobulin G. A number of post-translational modifications exist on the rFIX portion of the fusion protein. These PTMs consist of γ-carboxylation, in the Gla domain, of the first 12 glutamic acids; the majority of which occupy glutamic acids 1–10 and partial occupation of glutamic acids 11–12. Other possible modifi
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49

Tubío Santamaría, Nuria, Jonas Tönsing, Tina M. Schnoeder, et al. "Selective Dependency of MLL-Rearranged Leukemia on Immunoproteasome Function." Blood 134, Supplement_1 (2019): 529. http://dx.doi.org/10.1182/blood-2019-122100.

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Several cellular pathways control the fine balance between self-renewal and differentiation to maintain leukemia-initiating cell (LIC) function. To identify cellular dependencies with relevance for oncogenic fusion proteins, we performed global proteome profiling. Acute myeloid leukemia (AML) was induced by retroviral expression of either MLL-AF9 (MA9) or AML1-ETO9a (AE) in murine hematopoietic stem and progenitor cells (HSPCs) (Lineage-Sca1+Kit+, LSK) which were subsequently transplanted into irradiated syngeneic recipients. After onset of leukemia, LIC-enriched (GFP+ Kithigh) cells isolated
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Arking, Dan E., Amit Khera, Chao Xing, Wen H. Kao, and Aravinda Chakravarti. "Abstract 4401: Two Independent Genetic Variants in NOS1AP are Associated with QT interval in a Multi-Ethnic Population: the Dallas Heart Study." Circulation 118, suppl_18 (2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_882.

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Extremes of QT interval are associated with increased risk for sudden cardiac death (SCD), and thus identification and characterization of genetic variants that modulate QT interval may elucidate the underlying etiology of SCD. Previous work revealed an association between a common genetic variant in NOS1AP and QT interval in populations of European ancestry, but this finding has not been extended to other ethnic populations. We thus sought to characterize the effects of NOS1AP genetic variants in the multi-ethnic population-based Dallas Heart Study (DHS). Among 3,557 participants in DHS with
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