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1

Jones, Christian. MS: My story. Artshare South West (Cornwall) in conjunction with The Multiple Sclerosis Society of Great Britain and Northern Ireland (Mid-Cornwall Branch), 1989.

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2

Harrold, Kimberly. Sometimes MS is yucky. Science & Humanities Press, 2005.

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3

McLaughlin, Chris. Multiple sclerosis: A positive approach to living with MS. Bloomsbury, 1997.

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4

T, Fraser Robert, ed. The MS workbook: Living fully with multiple sclerosis. New Harbinger Publications, 2005.

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5

Devine, Monique. How to talk about ms with your children: A guide for parents. Multiple Sclerosis Society of Ireland, 2003.

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6

Eerdekens, Jeanine. Chronische ziekte en rolverandering: Een sociologisch onderzoek bij MS-patiënten. Acco, 1989.

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7

Sahraian, M. A. (Mohammad Ali) and SpringerLink (Online service), eds. MRI Atlas of MS Lesions. Springer-Verlag, 2008.

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8

Romberg, Anders. MS ja liikunta: Iloa, elämänlaatua, toimintakykyä. Edita, 2005.

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9

1962-, Russell Margot, ed. When the road turns: Inspirational stories about people with MS. Health Communications, 2001.

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10

Reed, Sue. Journey of a soul: In an MS body. Adams Press, 1990.

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11

Weiner, Howard L. Curing MS: How science is solving the mysteries of multiple sclerosis. Crown Publishers, 2004.

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12

Lake, John, and Rachel Evans. MS talent: A collection of short stories, poetry and memoirs. Jasmine Cottage, 2007.

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13

David, Carroll. Living well with MS: A guide for patient, caregiver, and family. HarperPerennial, 1993.

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14

Graham, Judy. Managing multiple sclerosis naturally: A self-help guide to living with MS. Healing Arts Press, 2010.

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15

Brennfleck, Shannon Joyce, ed. Multiple sclerosis sourcebook: Basic consumer health information about multiple sclerosis (MS) and its effects on mobility, vision, bladder function, speech, swallowing, and cognition, including facts about risk factors, causes, diagnostic procedures, pain management, drug treatments, and physical and occupational therapies ... Omnigraphics, Inc., 2007.

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16

Brennfleck, Shannon Joyce, ed. Multiple sclerosis sourcebook: Basic consumer health information about multiple sclerosis (MS) and its effects on mobility, vision, bladder function, speech, swallowing, and cognition, including facts about risk factors, causes, diagnostic procedures, pain management, drug treatments, and physical and occupational therapies ... Omnigraphics, Inc., 2007.

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17

Spence, Regina E. Mutley's great adventure: What I've learned living with MS. Branden Books, 2015.

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18

Shelley, Ross, ed. Multiple sclerosis: New hope and practical advice for people with MS and their families. Simon & Schuster, 1992.

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19

Hancock, Laura M., Jared M. Bruce, and Sharon G. Lynch. Multiple Sclerosis. Edited by C. Steven Richards and Michael W. O'Hara. Oxford University Press, 2013. http://dx.doi.org/10.1093/oxfordhb/9780199797004.013.020.

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Multiple sclerosis (MS) is a chronic disease that affects the central nervous system and can cause a wide variety of both physical and cognitive deficits. Mood disturbances are common, with as many as 50% of patients receiving a diagnosis of major depression during their lifetime. The risk of suicide is high and leaving depression untreated is associated with a host of additional MS symptoms. Depression in MS presents clinicians with unique challenges, as it is often difficult to distinguish from common neurological symptoms. The authors discuss recommended screening tools and therapeutic meth
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20

Miller, Aaron E., and Teresa M. DeAngelis. Multiple Sclerosis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199732920.003.0001.

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Multiple sclerosis (MS), the most common cause of disability due to a neurological disease in young adults, can pose a challenging diagnosis. In this chapter, we summarize the typical symptomatology and the radiographic and paraclinical findings in MS. In addition, we briefly review candidate differential diagnostic entities, the current diagnostic criteria, and therapeutic options.
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21

Iezzoni, Lisa I. Multiple Sclerosis. ABC-CLIO, LLC, 2010. http://dx.doi.org/10.5040/9798400688379.

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Written for students interested in learning about multiple sclerosis, this book describes how this frequently disabling disease affects patients, exploring its effects on minds, bodies, and daily lives. Written by a professor of medicine who is also personally affected by the disease, Multiple Sclerosis offers an overview of every aspect of the condition. It begins by introducing the central nervous system and describing how multiple sclerosis affects the brain and spinal cord. The author then reviews early understanding of MS, how it was first recognized as a disease, and the discoveries that
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22

Tillema, Jan-Mendelt, J. Graves, L. A. Benson, et al. Pediatric Multiple Sclerosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0022.

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Increased interest in pediatric-onset multiple sclerosis (MS) has contributed to improved knowledge of the presentation and evolution of central nervous system demyelinating diseases in childhood. This chapter reviews the unique features and challenges related to pediatric MS. The close proximity of pediatric MS to the biological onset of the disease provides a unique window into disease pathogenesis at stages of life when innate and adaptive immune pathways are still maturing. It is expected that the interplay between genetics, epigenetics, environmental exposures, and the maturing central ne
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23

Nygren, Kirstin, and Gail Hartley. Multiple Sclerosis Nursing. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0024.

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At each point across the disease spectrum, the MS nurse plays a pivotal role in the symptom management and comprehensive care of patients with multiple sclerosis. Multiple sclerosis most often affects young adults in the prime of life, derailing and interrupting goals and plans for the future. Whereas a neurologist might look at the disease burden of the brain, the MS nurse looks at the burden on a patient’s life. This nursing approach enables the MS nurse to help patients adjust and adapt to changes and symptoms as disease progression occurs and to empower them to live with the highest qualit
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24

Kaplan, Tamara B., and Marcelo Matiello. Multiple Sclerosis. Edited by Angela O’Neal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190609917.003.0026.

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Multiple sclerosis (MS) often affects women of childbearing age. There are many issues to consider when counseling women about their disease and treatment during this time. The Pregnancy in Multiple Sclerosis (PRIMS) study, published in 1998, is the best large-scale prospective study published to date. Based on this trial, and those that followed, it is recognized that the rate of relapse in MS decreases during pregnancy, especially during the third trimester, but there is a significant increase in relapse rate in the first three months postpartum. If relapses do occur during pregnancy, women
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25

Fabela, Damien. Multiple Sclerosis : How to Overcome MS: Primary Progressive Multiple Sclerosis. Independently Published, 2021.

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26

Popescu, Bogdan Florin Gh, Yong Guo, and Claudia Francesca Lucchinetti. Multiple Sclerosis: Pathology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0081.

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The pathology of MS consists of areas of focal demyelination, known as plaques or lesions, characterized by inflammation, gliosis, and relative axonal preservation. Recent neuropathological studies have established that white matter lesions are heterogenous with respect to the targets of injury and mechanisms of demyelination, highlighting the need for the identification of surrogate clinical and/or paraclinical markers that would correlate with immunopatterns in the general MS population and for the design of novel therapeutic strategies specifically tailored to each immunopattern. Recent neu
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27

Esch, Megan, and Nancy L. Sicotte. Neuroimaging in Multiple Sclerosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0007.

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Magnetic resonance imaging (MRI) of the brain and spinal cord plays an integral role in establishing the diagnosis of multiple sclerosis (MS). The use of MRI leads to earlier recognition of MS, allowing for earlier treatment initiation and more efficient monitoring of disease treatment and progress. This chapter outlines conventional MRI imaging sequences that are used to evaluate MS white matter lesions in the central nervous system. It also addresses the incorporation of new imaging techniques that have increased understanding of clinically definite MS, its variants, and how various diseases
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28

Ironside, Linda, Julie Zuby, and Flora MacLeod. Sharing Ms: Multiple Sclerosis (Remarkable Women). White Knight Publications, 2003.

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29

Canton, Chamein. Ms. Doesn't Stand for Multiple Sclerosis. Writers Club Press, 2001.

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30

Mansell, Morgan. Don't Ms with Me: Multiple Sclerosis. Independently Published, 2021.

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31

Hebert, Jeffrey R. Exercise and Multiple Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0086.

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The Centers for Disease Control and Prevention has stated that significant health benefits are obtainable for persons with disability who engage in physical activity, recommending 30 to 40 minutes of daily, moderately intense activity. However, persons with MS are frequently physically inactive, with findings of a 6-month activity reduction rate of 6%. This progressive lessoning of physical activity over time is a major contributor to worsening of symptoms and ancillary medical complications such as cardiovascular disease, obesity, and impaired bone health, underpinning the importance of exerc
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32

Namerow, Norman S. Multiple Sclerosis and Pain. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0019.

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Pain is one of the most prevalent symptoms in persons with MS, and may also complicate other symptoms due to MS such as fatigue, impaired mobility and sleep disturbances. Thus, diagnosis and treatment of pain has become an increasingly important aspect in MS management. The epidemiology of pain in patients with multiple sclerosis is reviewed in this chapter, and a pain classification is presented. Pain syndromes are also reviewed, and appropriate treatments are described. Neuropathic pain in particular is discussed, including current views on the pathophysiology of pain production. An algorith
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33

Ferini-Strambi, Luigi, and Sara Marelli. Sleep disorders in multiple sclerosis. Edited by Sudhansu Chokroverty, Luigi Ferini-Strambi, and Christopher Kennard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682003.003.0033.

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Though often unrecognized, sleep disorders in MS are seen at higher frequency than the general population, and they may contribute to pain, fatigue and depression—symptoms commonly observed in MS patients. Since several immunological factors in serum have been implicated in the development of sleep disorders, and MS is proven to be characterized by immune abnormalities, the notion that MS and sleep disorders share a similar background seems reasonable. Investigation of sleep disorders in MS is important, especially considering that the treatment of sleep disturbance may contribute to a reducti
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34

Talley, Colin L. A History of Multiple Sclerosis. Praeger, 2008. http://dx.doi.org/10.5040/9798400665097.

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While we now recognize that MS is a common neurological disease, as late as the early twentieth century it was considered a relatively rare condition in Europe and the United States. It was only in the late 1860s that MS came to be generally recognized as a distinct disease apart from other paraplegic maladies. One of the important historical questions about MS is whether it was a new disease of the nineteenth century or one that had simply gone unrecognized for a long time. Answering this question is complicated by the different frames or ways physicians understood and explained disease in pr
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35

Costello, Kathleen, Rosalind Kalb, and Barbara S. Giesser. Navigating Life with Multiple Sclerosis. 2nd ed. Oxford University PressNew York, 2025. https://doi.org/10.1093/oso/9780197748695.001.0001.

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Abstract This book is a practical guide for meeting the challenges of multiple sclerosis (MS), a lifelong, unpredictable disease. MS causes a myriad of physical, cognitive, and emotional symptoms that impact function and quality of life for those with the disease and those who provide care and support for them. The book demystifies MS and offers detailed descriptions of the essential components of comprehensive MS care, including disease and symptom management; rehabilitation to enhance function, safety, and independence; social and emotional support; and attention to overall health and wellne
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36

Polevoy, Cary J., and Chris Bogard-Reynolds. MS Toolkit. Lulu.com, 2006.

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37

Costello, Kathleen, and Scott D. Newsome. Symptoms of Multiple Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0085.

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Symptoms of MS can be categorized as primary, secondary, or tertiary. Primary symptoms are those that are a direct result of CNS damage, such as fatigue, bladder dysfunction, visual disturbances, incoordination or imbalance, etc. Secondary symptoms are complications arising from these symptoms such as falls due to imbalance, spasticity or weakness, or UTI due to bladder retention. Tertiary symptoms are the social and vocational consequences of primary and secondary symptoms and can include divorce, job loss, financial hardship, and social isolation. Careful evaluation of these symptoms along w
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38

Piccio, Laura, and Anne H. Cross. Immunology of Multiple Sclerosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0004.

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Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous system that targets myelin but affects both white matter and gray matter. Multiple sclerosis is thought to be mediated by cells of the adaptive and innate immune systems. CD4+ T lymphocytes of the Th1 and Th17 subtypes are believed to be critical for the initiation of multiple sclerosis. Treatment with monoclonal antibodies that deplete B lymphocytes has proven that B cells are critical to relapse development in multiple sclerosis. While immunopathophysiology is clearly important in MS, whether multiple sc
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39

People With MS With the Courage to Give. Red Wheel/Weiser, 2003.

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40

Williams, Mitzi. MS Made Simple: Multiple Sclerosis Management Journal. Purposely Created Publishing Group, 2019.

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41

Living with Multiple Sclerosis: Life Beyond MS. Independently Published, 2021.

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42

Steinbert, Kate. Meet MS: Explaining Multiple Sclerosis to Children. BookBaby, 2020.

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43

Ellison, Bonnie Lynne. Ms Entertainer: Rodeo, Music, and Multiple Sclerosis. iUniverse.com, 2010.

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44

Slimp, Jefferson C. Neurophysiology of Multiple Sclerosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199341016.003.0003.

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Any discussion of the pathomechanisms and treatments of MS benefits from an understanding of the physiology of the neuronal membrane and the action potential. Neurons and glia, are important for signal propagation, synaptic function, and neural development. The neuronal cell membrane, maintains different ionic environments inside and outside the cell, separating charge across the membrane and facilitating electrical excitability. Ion channels allow flow of sodium, potassium, and calcium ions across the membrane at selected times. At rest, potassium ion efflux across the membrane establishes th
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45

Waldman, Jackie. People with MS with the Courage to Give. Mango Media, 2003.

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46

Miller, Aaron E., and Teresa M. DeAngelis. Pregnancy and Multiple Sclerosis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199732920.003.0006.

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The risk of MS relapse is lower during pregnancy but significantly higher in the postpartum period. There are several key management issues to address in women of childbearing age with multiple sclerosis who are pregnant or in family planning. In this chapter, we review important therapeutic issues regarding peripartum and postpartum disease management, data regarding the prospect of breastfeeding, and the psychosocial support and counseling to help patients and their families navigate these decisions.
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47

Monagle, Simon. Multiple Sclerosis Treatment : Ways to Live with MS Positively: How to Fight Multiple Sclerosis. Independently Published, 2021.

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48

Orsetti Furney, Kym. When the Diagnosis Is Multiple Sclerosis. Praeger, 2007. http://dx.doi.org/10.5040/9798216035039.

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Kym Orsetti Furney was a 34-year-old physician, specializing in Internal Medicine, busy with her exciting job and enjoying life with her husband and young daughter in 2000, when she suddenly began to experience dizziness repeatedly, which rapidly led to a diagnosis of Multiple Sclerosis. Her world was rocked for a time, but Furney has recovered from the shock and - empowered by information, acceptance and support - continues working as a doctor, teaching and taking care of her family, despite the challenges of MS. For all people dealing with a personal or family diagnosis now, she offers help,
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49

Kaplan, Tamara, and Tracey Milligan. Demyelinating Diseases 1: Multiple Sclerosis (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190650261.003.0013.

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The video in this chapter explores demyelinating diseases, and focuses on multiple sclerosis (MS). It discusses the causes of MS, its etiology, symptoms (optic neuritis, sensory changes, weakness, spasticity, and bowel and bladder dysfunction), and subtypes (relapsing remitting (RRMS), secondary progressive (SPMS), and primary progressive (PPMS)).
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50

Absinta, Martina, and Daniel S. Reich. Multiple Sclerosis: MRI and Other Imaging Approaches in MS. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0082.

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Aside from its paramount diagnostic role, imaging techniques, particularly magnetic resonance imaging (MRI), provide unparalleled insights into multiple sclerosis (MS) by assessing the spatiotemporal dynamics of the associated inflammation and neurodegeneration. This dynamical view, predicated on interrogation of individuals with MS at multiple time points, is impossible with pathology. The chapter approaches MRI in MS from this perspective, describing features related to lesion development and location, as well as assessment of global and regional damage. It summarizes current knowledge, addr
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