Academic literature on the topic 'MSCA PF'

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Journal articles on the topic "MSCA PF"

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Le, Huërou Armelle. "Circulation des Pères grecs dans l'Occident médiéval: du nouveau sur les traductions d'Angelo Clareno." Etudes Franciscaines 17, no. 2 (2024): 307–29. https://doi.org/10.5281/zenodo.14775586.

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Premiers r&eacute;sultats de l'enqu&ecirc;te sur la circulation de plusieurs textes asc&eacute;tiques grecs traduits par le dissident franciscain Angelo Clareno (+1337) dans le cadre du projet TRANSMAR (Angelo Clareno (ca. 1260-1337) as a marginal Translator of the Greek Fathers : Circulation of Texts and People in Europe before Humanism) - HORIZON-MSCA-2022-PF-01 101105680. Examen de la tradition manuscrite des traductions de la <em>Scala Paradisi</em> de Jean Climaque, des <em>Asc&eacute;tiques </em>de Basile de C&eacute;sar&eacute;e, des&nbsp;<em>150 chapitres</em> du pseudo-Macaire. Liste
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Díaz-Payno, P. J., J. Llorca, A. D. Lantada, and J. Patterson. "DEVELOPMENT OF A DYNAMIC COIL-SHAPED SCAFFOLD FOR ARTICULAR CARTILAGE TISSUE ENGINEERING." Orthopaedic Proceedings 106-B, SUPP_2 (2024): 34. http://dx.doi.org/10.1302/1358-992x.2024.2.034.

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Even minor lesions in articular cartilage (AC) can cause underlying bone damage creating an osteochondral (OC) defect. OC defects can cause pain, impaired mobility and can develop to osteoarthritis (OA). OA is a disease that affects nearly 10% of the population worldwide[1], and represents a significant economic burden to patients and society[2]. While significant progress has been made in this field, realising an efficacious therapeutic option for unresolved OA remains elusive and is considered one of the greatest challenges in the field of orthopaedic regenerative medicine[3]. Therefore, the
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Ballestín, A., C. Pichol-Thievend, G. Bourmeau, et al. "P10.20.B POSTOPERATIVE ISCHEMIA CAUSED BY MICROSURGICAL RESECTION PROMOTES PRONEURAL-TO-MESENCHYMAL TRANSITION IN GLIOBLASTOMA." Neuro-Oncology 25, Supplement_2 (2023): ii66—ii67. http://dx.doi.org/10.1093/neuonc/noad137.218.

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Abstract BACKGROUND Four glioblastoma (GB) cellular states drive the intratumoral heterogeneity of this lethal primary brain tumor and are influenced by genetics, the tumor microenvironment (TME), and response to treatment. The impact of microsurgical resection on the TME and plasticity of GB cells is unknown. Postoperative cerebral ischemic events have been described after these surgical resections, altering the proper distribution of subsequent chemo-radiotherapy treatment. Despite the aggressive standard of care, 90% of patients experience recurrence a few months after treatment and it usua
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董, 怡含. "Research Progress in MSC Treatment of COVID19-Induced PF." Advances in Clinical Medicine 14, no. 04 (2024): 568–75. http://dx.doi.org/10.12677/acm.2024.1441061.

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Li, Xiaohong, Chen Li, Yiting Tang, et al. "NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis." American Journal of Physiology-Lung Cellular and Molecular Physiology 315, no. 3 (2018): L404—L421. http://dx.doi.org/10.1152/ajplung.00002.2018.

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Endogenous glutamate (Glu) release and N-methyl-d-aspartate (NMDA) receptor (NMDAR) activation are associated with lung injury in different animal models. However, the underlying mechanism is unclear. Bone marrow-derived mesenchymal stem cells (BM-MSCs), which show potential use for immunomodulation and tissue protection, play a protective role in pulmonary fibrosis (PF) process. Here, we found the increased Glu release from the BM cells of bleomycin (BLM)-induced PF mice in vivo. BLM stimulation also increased the extracellular Glu in BM-MSCs via the antiporter system xc− in vitro. The gene e
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Neher, Budrun, Md Abdul Gafur, Muhammad Abdullah Al-Mansur, Md Mahbubur Rahman Bhuiyan, Md Rakibul Qadir, and Farid Ahmed. "Investigation of the Surface Morphology and Structural Characterization of Palm Fiber Reinforced Acrylonitrile Butadiene Styrene (PF-ABS) Composites." Materials Sciences and Applications 05, no. 06 (2014): 378–86. http://dx.doi.org/10.4236/msa.2014.56043.

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Luo, Yukai, Shuang Zhou, Xiaojing Zhang, et al. "The role of the microbiota and metabolites in the treatment of pulmonary fibrosis with UC-MSCs: Integrating fecal metabolomics and 16S rDNA analysis." PLOS ONE 20, no. 1 (2025): e0313989. https://doi.org/10.1371/journal.pone.0313989.

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Introduction Pulmonary fibrosis (PF) is a chronic and irreversible interstitial lung disease characterized by a lack of effective therapies. Mesenchymal stem cells (MSCs) have garnered significant interest in the realm of lung regeneration due to their abundant availability, ease of isolation, and capacity for expansion. The objective of our study was to investigate the potential therapeutic role of umbilical cord-derived MSCs (UC-MSCs) in the management of PF, with a focus on the alterations in the gut microbiota and its metabolites during the use of UC-MSCs for the treatment of pulmonary fib
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Bar-Zeev, Yoram. "The guide to MSCA PF funding scheme." July 13, 2021. https://doi.org/10.5281/zenodo.5094280.

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The Marie&nbsp;Skłodowska-Curie Actions Postdoctoral Fellowships (MSCA PF) funding scheme seeks to support researchers&rsquo; career paths through mobility, while also attracting talented researchers to the EU and increasing knowledge and skills&rsquo; transfer. The program supports excellent researchers (holding a PhD) who wish to conduct research activities abroad to acquire new skills, gain diverse research experience and further develop their career and capabilities. Continue reading to learn more about the MSCA PF and its unique characteristics.&nbsp;
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Laudański, Piotr, Gabriela Rogalska, Damian Warzecha, et al. "Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis." Human Reproduction, February 7, 2023. http://dx.doi.org/10.1093/humrep/dead011.

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Abstract STUDY QUESTION Are there specific autoantibody profiles in patients with endometriosis that are different from those in controls? SUMMARY ANSWER This study did not reveal a significantly higher prevalence of autoantibodies in the studied groups of patients. WHAT IS KNOWN ALREADY Various inflammatory factors are postulated to be involved in the pathomechanisms of endometriosis, and a potential link exists with autoimmune diseases, which may also play an important role. As the diagnosis of endometriosis remains invasive, it can only be confirmed using laparoscopy with histopathological
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Fang, Yue‐Fei, Chen Zhang, Meng‐Meng Han, et al. "Engineered MSCs Break Endothelial‐Myofibroblast Crosstalk in Pulmonary Fibrosis: Reconstructing the Vascular Niche." Advanced Materials, February 28, 2025. https://doi.org/10.1002/adma.202414601.

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AbstractIn the progress of pulmonary fibrosis (PF), the normal vascular niche plays a crucial role in alveolar regeneration by secreting angiocrine factors. However, the malignant interaction between myofibroblasts and vascular endothelial cells results in significant loss of pulmonary capillaries in fibroblast foci, which promotes continuous deterioration of fibrosis. Herein, an engineered mesenchymal stem cell (MSC) therapeutic named MSC‐MM@LPHN is developed for reconstructing the vascular niche, which is formed by modifying the surface of MSC with ROS‐responsive lipid polymeric hybrid nanop
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Book chapters on the topic "MSCA PF"

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Cristina Russu, Manuela. "A New Era for a New Concept: Endometrial/Menstrual Mesenchymal Stem Cells and Their Secretome for Prevention and Treatment of pelvic Floor Disorders." In Obstetrics and Gynecology. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.114088.

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High-rate complications and recurrences in reconstructive surgery using in situ synthetic/polypropylene meshes have driven to a new era of mesenchymal stem cells (MSCs) and/or their exosomes/microvesicles for tissue homeostasis restoration, in pelvic floor disorders (PFD) prevention and/or therapy: pelvic organ prolapse, stress urinary incontinence, and posterior compartment pathology. Molecular pathophysiology knowledge along a woman’s life and results from endometrial/menstrual MSCs (eMSCs/MenSCs) in small/large animal models facilitate the new concept of translation in human clinical practice. New strategies are cell-based – vaginal, urethral, anal injections or systemic introduced – tissue engineering with new generation meshes/scaffolds seeded with eMSCs/MenSCs or their exosomes which are proposed in PFD prevention/therapy. Being easily collected, isolated with specific markers, and cultured for number harvesting, without ethics, immune compatibility, genetic, and oncogenic issues, and with unique biologic properties, eMSCs/MenSCs differentiate in many cellular types, preserving shape and phenotype in collagen and elastin fibers. eMSCs/MenSCs influence the microenvironment by paracrine/bioactive molecules to facilitate tissue repair. The advantages of surgery/augmentation by new generation meshes/scaffolds include quick restoring effects, mediated by angiogenesis, cell proliferation/differentiation in native/original PF cells, apoptosis inhibition, no chronic inflammation, reduced foreign body reactions, less thick collagen fibers and fibrosis, improving connective/neuromuscular tissues, less PF stiffness, and more elasticity. eMSCs/MenSCs are appropriate for PFD management, respecting good protocols for women safety.
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Cristina Russu, Manuela. "Studies on Endometrial Mesenchymal Stem Cells in Female Regenerative Pelvic Floor Medicine." In Studies on Female Pelvic Medicine [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1010815.

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Unexpected and unwanted results of synthetic/polypropylene meshes in pelvic reconstructive surgery have driven to animal and human regenerative medicine studies on adult mesenchymal/stromal stem cells for tissues’ normal microstructure and function restoration. Contemporary knowledge on tissues’ molecular/cellular structure and physiology is the basis for the new concept of mesenchymal/stromal stem cells’ capacities along women’s life in pelvic organ prolapse, stress urinary incontinence, and posterior pelvic floor (PF) compartment pathology. Mesenchymal endometrial/menstrual stem cells (eMSCs/MenSCs) and/or their exosomes/microparticles/secretome are recently most studied stem cells in regenerating pelvic floor tissue, being proven without ethic, immune compatibility, genetic and oncogenic risks, from their unique biologic properties—differentiation in many cellular types, fibres, and influences on surrounding microenvironment by paracrine/bioactive molecules to pelvic tissue repair. The preclinical studies showed eMSCs/MenSCs’ benefits: quick appeared restoring effects and improved connective/neuromuscular tissues without chronic inflammation and foreign body reactions. One discusses good protocols for women’s maximum safety and minimum risks, accomplished by direct vaginal, urethral, and anal injections or by systemic. Intravenous administration or by new generation eMSCs/MenMSCs seeded meshes/scaffolds for surgery augmentation in order to show the advantages over other MSCs types in female pelvic floor medicine.
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Conference papers on the topic "MSCA PF"

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Chiang, Chen-En, Yu-Chun Lin, Megha Jhunjhunwala, Hui-Ling Lin, and Chi-Shuo Chen. "Late Breaking Abstract - Evaluating the clinical potential of inhalation of umbilical cord mesenchymal stem cell (UC-MSC) exosomes in pulmonary fibrosis (PF) treatment." In ERS Congress 2024 abstracts. European Respiratory Society, 2024. http://dx.doi.org/10.1183/13993003.congress-2024.pa5169.

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