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Journal articles on the topic 'MSG'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Baskara, Angga, I. N. Arsana, and N. K. A. Juliasih. "GAMBARAN HISTOPATOLOGI HATI TIKUS WISTAR (Rattus norvegicus) PASCA PEMBERIAN MONOSODIUM GLUTAMAT." JURNAL WIDYA BIOLOGI 10, no. 01 (2019): 68–75. http://dx.doi.org/10.32795/widyabiologi.v10i01.238.

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Monosodium glutamate (MSG) has been used very widely in the community as a food flavoring, and is thought to have a detrimental effect. This study aims to determine the effect of MSG on liver histopathology. 28 Wistar rats were used in this study. Rats were grouped into four groups: control (K), MSG-1 (MSG dose 1.5 mg / g bodyweight), MSG-2 (MSG dose 3.5 mg / g bw), and MSG-3 (MSG dose 4, 5 mg / g bw). MSG is given every day for 30 days. At the end of the treatment, the rat were euthanized and dissected for taking the liver. Histology preparation were made using the paraffin method and stained

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Li, Jingzhen, Xiaojing Ma, Igbe Tobore, et al. "A Novel CGM Metric-Gradient and Combining Mean Sensor Glucose Enable to Improve the Prediction of Nocturnal Hypoglycemic Events in Patients with Diabetes." Journal of Diabetes Research 2020 (November 2, 2020): 1–8. http://dx.doi.org/10.1155/2020/8830774.

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Nocturnal hypoglycemia is a serious complication of insulin-treated diabetes, and it is often asymptomatic. A novel CGM metric-gradient was proposed in this paper, and a method of combining mean sensor glucose (MSG) and gradient was presented for the prediction of nocturnal hypoglycemia. For this purpose, the data from continuous glucose monitoring (CGM) encompassing 1,921 patients with diabetes were analyzed, and a total of 302 nocturnal hypoglycemic events were recorded. The MSG and gradient values were calculated, respectively, and then combined as a new metric (i.e., MSG+gradient). In addi

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Gaurav, Sheetabh, Sebastian Egli, Boris Thies, and Jörg Bendix. "Harmonization of Meteosat First and Second Generation Datasets for Fog and Low Stratus Studies." Remote Sensing 15, no. 7 (2023): 1774. http://dx.doi.org/10.3390/rs15071774.

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Operational weather satellites, dating back to 1970s, currently provide the best basis for climatological investigations, such as an analysis of changes in the cloud cover. Because clouds are highly dynamic in time, temporally high-resolution data from the geostationary orbit are preferred in order to take variations in the diurnal cycles into account. For such studies, a consistent dataset in space and time is mandatory, but not yet available. Ground-based point measurements of various cloud parameters, such as ceiling, visibility, and cloud type are often sparsely spread and inconsistent, ma

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Bates, Jane. "MSG mystery." Nursing Standard 29, no. 20 (2015): 28–29. http://dx.doi.org/10.7748/ns.29.20.28.s30.

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Das, Debasmita, Arnab Banerjee, Ankita Bhattacharjee, Sandip Mukherjee, and Bithin Kumar Maji. "Dietary food additive monosodium glutamate with or without high-lipid diet induces spleen anomaly: A mechanistic approach on rat model." Open Life Sciences 17, no. 1 (2022): 22–31. http://dx.doi.org/10.1515/biol-2022-0004.

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Abstract Globally, the trend of using food additives and eating ready-made fast food has led to a deleterious impact on immune organs. Monosodium glutamate (MSG), as a food additive in a high-lipid diet (HLD), acts as a silent killer of immune cells. Hence, the present study aimed to evaluate the role of MSG in HLD on spleen injury in rats. Results showed that a 2.52-fold and 1.91-fold increase in spleen index in MSG and MSG + HLD group indicates splenomegaly, whereas a 1.36-fold and 1.29-fold increase in pro-inflammatory cytokines in MSG and MSG + HLD-fed rats, respectively, promote the infla

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Egbuonu, A. C. C., P. O. Alaebo, C. N. Uchukwu, et al. "Therapeutic Artemether-Lumefantrine Modulated Monosodium Glutamate-Related Adversity on Rats’ Kidney Histology and Antioxidant Response Bio-Indicators." Journal of Applied Sciences and Environmental Management 25, no. 5 (2021): 807–14. http://dx.doi.org/10.4314/jasem.v25i5.18.

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Co-intake-related interactive-synergistic influence of artemether-lumefantrine, AL and monosodium glutamate, MSG that separately mediated oxidative stress could be significant on the kidney actively involved in xenobiotic detoxification and elimination. Thus, influence of AL on rats’ kidney histomorphology and antioxidant bio-indicators following MSG-challenge was assessed. For 7 days, thirty rats (n = 5) were respectively exposed to vehicle (distilled water), therapeutic AL (TAL), high AL (HAL), MSG, MSG plus TAL or MSG plus HAL. Significant (P<0.05) results comparison showed highest and l

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Toyomasu, Yoshitaka, Erito Mochiki, Mitsuhiro Yanai, et al. "Intragastric monosodium l-glutamate stimulates motility of upper gut via vagus nerve in conscious dogs." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 298, no. 4 (2010): R1125—R1135. http://dx.doi.org/10.1152/ajpregu.00691.2009.

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Monosodium l-glutamate (MSG) is a substance known to produce the umami taste. Recent studies indicate that MSG also stimulates a variety of activities in the gastrointestinal tract through its receptor in the gut, but no study has reported the activity in conscious large experimental animals. The aim of our study was to investigate whether direct intragastric MSG stimulates gut motility and to identify the mechanism in conscious dogs. Contractile response to intraluminal injection of MSG was studied in the fed and fasted states by means of chronically implanted force transducers. MSG (5, 15, 4

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Müller-Enoch, Dieter, Robert Fintelmann, Andrey Nicolaev, and Hans Gruler. "Enzyme Activity of the Cytochrome P-450 Monooxygenase System in the Presence of Single Chain Lipid Molecules." Zeitschrift für Naturforschung C 56, no. 11-12 (2001): 1082–90. http://dx.doi.org/10.1515/znc-2001-11-1227.

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Abstract The influence of single chain lipids on the 7-ethoxycoumarin O-deethyase activity of the reconstituted binary protein complex of isolated cytochrome P450 and NADPH-cytochrome P450 reductase has been examined. The enzyme activity of this binary enzyme complex has been shown to be influenced by (i) altering the complexation process of both proteins, (ii) by altering the catalytic cycle time of the active binary protein complex and (iii) by altering the fraction of substrate molecules at the catalytic center of the enzyme. Competitive inhibition was measured for all single chain molecule

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Arapa, Zulyana, Sunarto Kadir, and Ekawaty Prasetya. "THE RELATIONSHIP BETWEEN THE CONSUMPTION OF FOODS CONTAINING MONOSODIUM GLUTAMATE (MSG) WITH THE INCIDENCE OF OBESITY IN STUDENTS OF SDN 4 SUWAWA TENGAH." Journal Health & Science : Gorontalo Journal Health and Science Community 7, no. 1 (2023): 122–27. http://dx.doi.org/10.35971/gojhes.v7i1.16112.

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Monosodium Glutamat (MSG) merupakan zat aditif pada makanan yang meningkatkan cita rasa makanan. Konsumsi MSG secara berlebihan dapat menyebabkan masalah kesehatan status gizi berlebih (overweight) hingga obesitas. Kebaruan penelitian ini karena meneliti tentang hubungan konsumsi makanan mengandung Monosodium Glutamat (MSG) dengan kejadian obesitas pada siswa. Tujuan penelitian ini untuk menganalisis hubungan konsumsi makanan mengandung Monosodium Glutamat (MSG) dengan kejadian obesitas pada Siswa SDN 4 Suwawa Tengah. Desain penelitian ini adalah Cross sectional dengan total sampel 99 responde

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Ajani, Olumide, Abraham Akinyemi, and Olumide Akinniyi. "Protective Effect of Tiger Nut (Cyperus Esculentus) Against Monosodium Glutamate-Induced Reproductive Dysfunction in Male Wistar Rats." Veterinary Sciences and Practices 20, no. 1 (2025): 16–23. https://doi.org/10.17094/vetsci.1554163.

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Monosodium glutamate (MSG) is a widespread flavour enhancer linked to health risks, including male reproductive dysfunction. This study investigated tiger nut (Cyperus esculentus) as a potential protective agent against MSG-induced reproductive issues in male Wistar rats. Forty adult rats were divided into four groups: control, MSG-only (2 mg/g), tiger nut-only (500 mg/kg), and MSG+tiger nut combination (2 mg/g MSG + 500 mg/kg tiger nut). Treatments were administered orally for 28 days, with analyses conducted at days 14 and 28. Results showed significant variations in sperm parameters. At 14

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Rachma, Firstca Aulia, and Tunik Saptawati. "Analysis Tolerance of Monosodium Glutamate (MSG) In instant noodles With Uv-Vis Spectrophotometry." Journal of Science and Technology Research for Pharmacy 1, no. 1 (2021): 20–24. http://dx.doi.org/10.15294/jstrp.v1i1.43568.

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Background: MSG has become one of the most widely used food flavorings in the world, the FDA (Food and Drug Administration) reported an average per capita intake of MSG in the United States of 550 mg / day in 1973. The use of MSG as a food additive has been regulated by its use. WHO. This rule stipulates that daily consumption of MSG per person should not exceed the safe threshold of 120 mg / kg / day. MSG is proven to be a risk factor for obesity. The increase in body weight in mice occurred after MSG was given as much as 15-30 mg / kg or the equivalent of 1-2 g / person. Based on the descrip

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Egbuonu, Anthony Cemaluk Chinedum, Prince Ogochukwu Alaebo, Udumma Nsofor Onuoha, et al. "Therapeutic Azithromycin Mitigated Monosodium Glutamate-Related Dysfunction in Rats’ Body Weight and Serum, Liver, Kidney and Heart Antioxidant Defense Bioindicators." Biology, Medicine, & Natural Product Chemistry 13, no. 1 (2024): 43–50. http://dx.doi.org/10.14421/biomedich.2024.131.43-50.

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Monosodium glutamate (MSG) mediates body weight gain (BWG) and oxidative stress. Azithromycin (AZT), may be abused and co-consumed with MSG to present unknown outcomes on BWG and oxidative stress. This study evaluated the effect of AZT and MSG in rats’ BWG and antioxidant bioindicators. Thirty rats assigned to five groups were orally exposed for seven consecutive days to groups A, control (distilled water, 1 ml/kg), B, MSG (MSG 8000 mg/kg), C, therapeutic AZT, TAZ (AZT 82.5 mg/kg), D, overdose AZT, OAZ (AZT 412.5 mg/kg) and E, TAZ + MSG (AZT 82.5 mg/kg + MSG 8000 mg/kg). MSG-treated rats exhib

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Jangga, Jangga, Saparuddin Latu, Nining Ade Ningsih, and Rosdiana Rosdiana. "PEMBERDAYAAN MASYARAKAT TENTANG CARA MENDETEKSI MONOSODIUM GLUTAMAT PADA MAKANAN DAN DAMPAKNYA TERHADAP KESEHATAN." SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan 6, no. 4 (2022): 1676. http://dx.doi.org/10.31764/jpmb.v6i4.10989.

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ABSTRAKMSG pada makanan yang dikonsumsi sering mengganggu kesehatan karena MSG akan terurai menjadi sodium dan glutamat. Garam dari MSG mampu memenuhi kebutuhan garam sebanyak 20-30%, sehingga konsumsi MSG yang berlebihan menyebabkan kenaikan kadar garam dalam darah. Tujuan kegiatan ini adalah meningkatkan pengetahuan masyarakat di wilayah kerja Puskesmas Minasa Upa Kecamatan Rappocini Kota Makassar tentang cara mendeteksi MSG pada makanan serta masyarakat dapat mengetahui dampak penggunaan MSG terhadap kesehatan. Metode yang digunakan pada kegiatan ini adalah dengan memberdayakan masyarakat p

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Sukmak, Manatsaphon, Thin Su Kyaw, Kanokwan Nahok, et al. "Urinary metabolic profile and its predictive indexes after MSG consumption in rat." PLOS ONE 19, no. 9 (2024): e0309728. http://dx.doi.org/10.1371/journal.pone.0309728.

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Monosodium glutamate (MSG) is a widely used food additive with conflicting evidence regarding its potential effects on human health, with proposed relevance for obesity and metabolic syndrome (MetS) or chronic kidney disease. As being able to accurately quantify the MSG dietary intake would help clarify the open issues, we constructed a predictive formula to estimate the daily intake of MSG in a rat model based on the urinary metabolic profile. Adult male Wistar rats were divided into groups receiving different daily amounts of MSG in drinking water (0.5, 1.5, and 3.0 g%), no MSG, and MSG with

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Maulina, Nora, Indra Zachreini, Gholib Gholib, Abdulhadi Suwandi, and Muslim Akmal. "Black garlic exhibited hepatoprotective effect against monosodium glutamate-induced hepatotoxicity in animal model." Narra J 4, no. 2 (2024): e799. http://dx.doi.org/10.52225/narra.v4i2.799.

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Monosodium glutamate (MSG) is commonly used as a flavor-enhancing agent in foods, and studies have demonstrated its toxic effects in animal models. Black garlic is known for its antioxidant and anti-inflammatory properties; however, there is a lack of studies on the potential hepatoprotective effect of black garlic ethanol extract (BGE) against MSG-induced hepatotoxicity in rats. The aim of this study was to investigate the hepatoprotective effects of ethanol extract of black garlic against MSG-induced liver damage in animal model. Twenty-five male Wistar rats were randomly assigned to five gr

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Suherlin, Ika, Wisnu Barlianto та Pande Made Dwijayasa. "THE EFFECT OF GREEN TEA EXTRACT ON THE NUMBER OF SECRETORIC EPITELEL CELLS AND EXPRESSION OF ESTROGEN- α RECEPTORS OF WISTAR FALLOPY TUBES EXPOSED TO MSG". Jambura Journal of Health Sciences and Research 4, № 3 (2022): 824–36. http://dx.doi.org/10.35971/jjhsr.v4i3.14873.

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Stres oksidatif dapat menyebabkan infertilitas melalui berbagai mekanisme, yaitu melalui ketidakseimbangan antioksidan dan radikal bebas, sehingga meningkatkan kerusakan seluler yang disebabkan oleh Reactive oxygen species (ROS). Monosodium glutamat (MSG) adalah garam natrium glutamat, yang digunakan sebagai bahan tambahan makanan sebagai penguat cita rasa. Pemberian MSG tikus secara oral dapat menyebabkan peningkatan Reactive Oxygen Species (ROS) sehingga terjadi stress oksidatif pada jaringan yang memiliki reseptor glutamat. MSG berpengaruh pada anatomi dan fungsi tuba yaitu jumlah sel epite

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Bakier, Marwa, Shaban Hemeda, Abeer Nahas, and Walaa Naby. "Ginger modulates gene expression of oxidative stress, single and double DNA strand breaks, and micronucleus induced by variant durations and doses of monosodium glutamate in mice." Alexandria Journal of Veterinary Sciences 75, no. 2 (2022): 78. http://dx.doi.org/10.5455/ajvs.17182.

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This study aims to compare the genotoxic effects of low and high MSG doses in short and long term (6-12 weeks) exposure, as well as to investigate the potential protective effect of ginger co-administration against MSG genotoxicity. The expression of antioxidant genes (GST, MT1, CAT) and single and double strand DNA repair genes (XRCC1, FEN1) were analyzed also to detect DNA damage using the micronucleus assay. 120 Swiss albino male mice were allocated into six groups for each time interval exposure. Group 1 (Control), Group 2 received daily 160 mg/kg b.wt ginger, Group 3 (100 mg/kg b.wt MSG),

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Muntaza, Yasmin, and Annis Catur Adi. "Hubungan Sumber Informasi dan Pengalaman dengan Tingkat Pengetahuan tentang Penggunaan Monosodium Glutamate (MSG) pada Ibu Rumah Tangga." Amerta Nutrition 4, no. 1 (2020): 72. http://dx.doi.org/10.20473/amnt.v4i1.2020.72-78.

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Background: Monosodium Glutamate (MSG) is a food additive that is often used by housewives as flavoring. However, the use of MSG is still controversial, especially in terms of health. This can cause a variety of information obtained by housewives so that it affects the use of MSG in daily life.Objectives: This study aimed to find out the relationship among information sources and experience with knowledge levels about the use of MSG in housewives.Methods: This study used cross sectional design. The sample sizes were 86 housewives who were recruited through simple random sampling. The data coll

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Syahputra, Tengku Muhammad Reza, Muhammad Ichwan, and Sufitni. "Efek Jus Semangka Terhadap Jumlah Dan Motilitas Spermatozoa Tikus Wistar Yang Dipapari MSG." HEALTH CARE : JURNAL KESEHATAN 8, no. 2 (2019): 43–50. http://dx.doi.org/10.36763/healthcare.v8i2.59.

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Latar Belakang: MSG merupakan asam glutamat digunakan sebagai penyedap makanan terutama produk makanan olahan. MSG dalam makanan olahan dapat melebihi kadar yang diperkirakan karena beberapa makanan olahan tidak mencantumkan pada label kemasan. Beberapa penelitian melaporkan efek MSG pada berbagai organ terutama testis. Konsumsi MSG jangka panjang dan berlebihan menyebabkan kerusakan testis akibat stres oksidatif sehingga terjadinya peroksidasi lipid. Antioksidan pada buah semangka berperan mencegah kerusakan oksidatif. Tujuan: untuk mengetahui efek jus semangka terhadap jumlah dan motil

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Al-Qtaitat, Aiman, Sinan S. Farhan, Aiman Al-Maathidy, Ghadeer Almuhaisen, and Jihad Alzyoud. "Potential Protective Effect of Pomegranate (Punica Granatum) Juice on Monosodium Glutamate Induced Seminiferous Tubules Changes in Adult Male Albino Rats: Histological Study." Biosciences Biotechnology Research Asia 16, no. 3 (2019): 625–36. http://dx.doi.org/10.13005/bbra/2778.

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Monosodium glutamate (MSG) has been recognized as flavor enhancer that adversely affects male reproductive systems. The present study was designed to investigate the potential protective effects of pomegranate juice on MSG induced histopathological changes in the seminiferous tubules of rats. Fifty adult male albino rats were divided into five groups of ten rats each; Group I (Control group), received daily standard diet only for one month. Group II (Pomegranate group), received daily pomegranate juice only for one month. Group III (MSG group), received daily a single dose of 60 mg/kg body wei

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Sagita, Ninit Putry, Endang Setyaningsih, Ulya Ananda Putri Febrianti, et al. "Kadar Protein Plasma Darah Tikus Putih (Rattus norvegicus) Bunting yang Mengkonsumsi MSG Organik dan MSG Sintetis." Bioscientist : Jurnal Ilmiah Biologi 13, no. 1 (2025): 665. https://doi.org/10.33394/bioscientist.v13i1.13457.

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This study aims to determine the levels of blood plasma protein in pregnant white rats (Rattus nervagicus) that consume Organic MSG and Synthetic MSG. This research method is experimental using a Completely Randomized Design (CRD) by random sampling 21 pregnant white rats with 3 replications and 7 treatments consisting of positive control treatments, P1 = 0.5 ml Organic MSG, P2 = 1 ml Organic MSG, P3 = 2 ml Organic MSG, P4 = 0.5 ml Synthetic MSG, P5 = 1 ml Synthetic MSG, P6 = 2 ml Synthetic MSG for 19 days. The variables measured were blood plasma protein levels measured using a refractometer

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Farombi, E. O., and O. O. Onyema. "Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin." Human & Experimental Toxicology 25, no. 5 (2006): 251–59. http://dx.doi.org/10.1191/0960327106ht621oa.

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Monosodium glutamate (MSG) continues to function as a flavor enhancer in West African and Asian diets. The present study examines the modulatory effects of dietary antioxidant vitamin C (VIT C), vitamin E (VIT E) and quercetin on MSG-induced oxidative damage in the liver, kidney and brain of rats. In addition, the effect of these antioxidants on the possible genotoxicity of MSG was investigated in a rat bone marrow micronuclei model. MSG administered intraperitoneally at a dose of 4 mg/g body wt markedly increase malondialdehyde (MDA) formation in the liver, the kidney and brain of rats. Simul

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Egbuonu, Anthony Cemaluk Chinedum, Emmanuel Obi, Chinedu P. Nwuke, et al. "Monosodium Glutamate Plus Artemether-lumefantrine Overdose Altered Malondialdehyde, Total Protein and Albumin Concentration in Rats." Advanced Journal of Graduate Research 7, no. 1 (2019): 70–79. http://dx.doi.org/10.21467/ajgr.7.1.70-79.

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This study aimed at assessing alterations in malondialdehyde, MDA, total protein and albumin concentration in the serum and liver homogenate of monosodium glutamate (MSG)-challenged rats co-treated with artemether-lumefantrine, AL. Methods involving colourimetric estimation were employed in thirty rats randomly grouped into six (n = 5) and for seven consecutive days, fed feed and water (Group A), AL therapeutic dose (Group B), AL overdose (therapeutic dose × 5) (Group C), MSG (8000 mg/kg body weight) (Group D), AL therapeutic dose plus MSG (Group E) or AL overdose plus MSG (Group F). Total pro

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Sari, Leli Mustika, Rahmadina Rahmadina, and M. Idris. "Effectiveness of Using A Combination of Rice Husk Ash and Monosodium Glutamate (MSG) on Growth of Lettude Plant (Lactuca sativa L.)." Jurnal Biologi Tropis 24, no. 3 (2024): 892–99. http://dx.doi.org/10.29303/jbt.v24i3.7514.

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Lettuce is a plant that is quite popular with the public. Not only does it have economic value but it also has quite high nutritional content. So one method used to maintain the stability of lettuce production on the market is by providing rice husk ash and monosodium glutamate (MSG). This research uses a non-factorial randomized block design (RAK) which consists of 5 levels, namely giving fertilizer without combination and giving combined fertilizer, namely P1 (Rice husk ash 100 grams/polybag), P2 (MSG 15 grams/polybag), P3 (Combination of rice husk ash and MSG with a dose ratio of 100 grams

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Savitri, Lisa, Elfred Rinaldo Kasimo, and Rochmad Krissanjaya. "Pemberian Monosodium Glutamat Selama Masa Organogenesis Meningkatkan Perkembangan Embrio Cacat pada Mencit." Jurnal Veteriner 24, no. 3 (2023): 328–34. http://dx.doi.org/10.19087/jveteriner.2023.24.3.328.

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Monosodium glutamate (MSG) biasanya berbentuk kristal halus dan berwarna putih. Senyawa MSG dibuat melalui proses fermentasi dari bahan dasar pati (gandum) dan gula molasses (tetes tebu) yang diberi nama sebagai garam natrium dan asam glutamat. Pemberian MSG selama induk mencit bunting bersifat embriotoksik. Penelitian ini bertujuan untuk mengetahui efek toksik MSG pada perkembangan embrio selama masa organogenesis. Penelitian pemberian MSG terhadap mencit dimulai pada kebuntingan hari ketujuh yaitu pada tahap organogenesis. Perlakuan dosis MSG yang diberikan adalah dosis 528 mg/kg BB, 696 mg/

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Itez, Paul, Godwin S. Aloh, Kelechi U. Osuocha, Adaku V. Iwueke, and Ezinne C. Chukwu. "Ameliorative potentials of methanol leaf extract of Newbouldia laevis on monosodium glutamate induced toxicity in female albino rats." African Journal of Biological Sciences 2, no. 3 (2020): 37–50. https://doi.org/10.33472/AFJBS.2.3.2020.37-50.

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<em>Newbouldia laevis</em> is a valuable tropical plant belonging to the family of <em>Bigoniaceae</em>. The plant is believed by most herbal practitioners to be the tree of fertility and of immense medicinal benefits to humans. This study examined ameliorative potencies of <em>Newbouldia laevis</em> on monosodium glutamate induced toxicity in female albino rats for 14 days. Group A received 800 mg/kg body weight of Monosodium Glutamate (MSG), while Group B received 8,000 mg of MSG + 400 mg of extract. Group C received 8,000 mg of MSG and 600 mg of N. laevis. Group D received feed and water. G

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Takai, Atsuko, Kentaro Kikuchi, Yusuke Kajiyama, et al. "Serological and Histological Examination of a Nonalcoholic Steatohepatitis Mouse Model Created via the Administration of Monosodium Glutamate." International Scholarly Research Notices 2014 (October 30, 2014): 1–7. http://dx.doi.org/10.1155/2014/725351.

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The administration of monosodium glutamate (MSG) to mice induces hepatic steatosis and inflammation. In this study, we investigated the metabolic features of MSG-treated mice and the histological changes that occur in their livers and adipose tissue. MSG mice were prepared by subcutaneously injecting MSG into newborn C57BL/6J male mice. The control mice were subcutaneously injected with saline. Another group of mice was fed a methionine- and choline-deficient diet (MCD). Compared with the control mice, the MSG mice had higher serum levels of insulin and cholesterol than the control mice, where

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Sispitasari, Yeti Eka. "Gambaran Histologi Ginjal Tikus Wistar Yang Terpapar MSG Setelah Perlakuan Diberikan Jus Tomat Dan Diberhentikan Perlakuan Saja." JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST 1, no. 2 (2018): 62. http://dx.doi.org/10.30651/jmlt.v1i2.1499.

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MSG causes many side effects on the body, but MSG has long been used as a food flavor that can bring tastes (umami) and play a role in strengthening the taste. The chemical structure of MSG is no different from Glutamic Acid (glutamate), it is one of the 20 amino acids that make up proteins in the body. So the use of MSG needs to be discontinued to prevent kidney damage due to continued consumption of MSG, two research were conducted to determine the effect of discharging of MSG consumption by being given tomato juice (1) and discharged without treatment (2), the second study was seen from the

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Ogunlabi, Olugbenga O., Bukunola O. Adegbesan, Adedayo A. Adebisi, and Emmanuel O. Ajani. "PRE-TREATMENT WITH PHYLLANTHUS AMARUS STALLS DYSLIPIDEMIA AND UTERINE TOXICITY IN MONOSODIUM GLUTAMATE ADMINISTERED RATS." African Journal of Science and Nature 9 (November 10, 2020): 1. http://dx.doi.org/10.46881/ajsn.v9i0.165.

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Studies have implicated intake of monosodium glutamate (MSG) in fibroid development, but reports on the correlation between dyslipidemia and fibroid induction with an intake of MSG are inconsistent. This study investigates the risk of dyslipidemia in MSG intake and the therapeutic effect of administration of Phyllanthus amarus. Forty adult female Wistar rats randomize to 5 groups of 8 rats each were used. MSG was administered continuously to groups 2-5 at 200 mg/Kg body weight for 28 days. After 28 days, blood was withdrawn from rats in groups1, 2 and 3after anaesthetizing with diethyl ether.

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Gedik-Soyuyuce, Ozlem, Pinar Yalinay-Dikmen, and Nazim Korkut. "The effect of migraine and motion sickness on symptoms evoked by the caloric vestibular test." Journal of Vestibular Research 32, no. 2 (2022): 135–44. http://dx.doi.org/10.3233/ves-210046.

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BACKGROUND: The caloric vestibular test (CVT) may evoke headache and vestibular symptoms in susceptible people. Patients with migraines have higher susceptibility to motion sickness. In migraines, impaired habituation to repetitive stimuli is a well-known interictal abnormality. OBJECTIVE: This study is aimed at evaluating CVT-evoked headache, nausea, vomiting, and imbalance in patients with and without migraine and/or motion sickness. METHODS: A retrospective data analysis was performed on 554 patients with a complaint of dizziness who underwent bithermal CVT at a tertiary referral center. Th

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Nolasco, Glen, Graciela Ann Escoto, Lourdes Fatima David, Aaron Carl Te, and Frienchie Ann Yamauchi. "Amelioration of Behavioral and Cognitive Impairment of Ethanolic Leaf Extract of Ziziphus Talanai Against MSG in Mice." Journal of Healthcare and Biomedical Science 2, no. 1 (2023): 24–34. http://dx.doi.org/10.31098/jhbs.v2i1.1835.

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Ziziphus talanai is an endemic plant species in the Philippines. Recently, this plant's phytochemical analysis revealed pivotal compounds with different pharmaceutical properties, including the neuroprotective activity in the mice cerebellum. Nonetheless, the scarcity of information on the neuroprotective potential of this plant has been a focal point. Thus, this study aimed to evaluate the neuroprotective potential of Z. talanai extract against MSG-induced aberrations in mice. A total of 24 mice were distributed and administered 9000mg/kg of MSG (T-), MSG and 1000mg/kg of L-taurine (T+), 100%

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Hassama, Paweena, Nang Myint Phyu Sin Htwe, Thawat Rattanaphan, Eaknarin Ruangrak, and Athakorn Promwee. "Effect of Monosodium Glutamate on the Growth and Quality of Sunflower Microgreens." ASEAN Journal of Scientific and Technological Reports 28, no. 2 (2025): e255735. https://doi.org/10.55164/ajstr.v28i2.255735.

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Microgreens are increasingly recognized as functional foods due to their low-calorie content and rich profile of micronutrients and antioxidants. Sunflower microgreens, in particular, are known for their high levels of protein, vitamin C, phenols, fiber, and antioxidant activity. This study aimed to investigate the effect of monosodium glutamate (MSG) as an alternative nitrogen fertilizer on the growth and quality of sunflower microgreens. Five treatments were tested: MSG 1 (639.2 mg/L), MSG 2 (319.6 mg/L), MSG 3 (159.8 mg/L), deionized water, and Hoagland and Arnon solution, using a Randomize

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Weliyani, Trima, Iwan Sahrial Hamid, Sri Hidanah, Ragil Angga Prastiya, and Prima Ayu Wibawati. "Effect of Robusta Coffee Extract on Histopathological in Mice Testes Induced with Monosodium Glutamat." Jurnal Medik Veteriner 4, no. 2 (2021): 243. http://dx.doi.org/10.20473/jmv.vol4.iss2.2021.243-248.

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Monosodium glutamate (MSG) is a sodium salt from glutamic acid which is currently very popular to be used as a food flavoring ingredient to stimulate appetite. Exessive consumption of MSG can disrupt the balance of antioxidants and ROS, and cause the negative effects of oxidative stress on testes. Coffee has high chlorogenic acid, function for antioxidants and reduce the negative effect on cell damage in the testes. This study aims to analyze the effect of robusta coffee extract on histological of mice testes induced with MSG. This study was completely randomized design (CRD), using 20 male mi

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Reza Anindita. "UJI SEDUHAN DAUN TEH HIJAU (Camelia sinensis L.) PADA GINJAL MENCIT YANG DIBERI MONOSODIUM GLUTAMAT (MSG)." Borneo Journal of Pharmascientech 3, no. 2 (2019): 189–99. https://doi.org/10.51817/bjp.v3i2.257.

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ABSTRAKPenelitian ini bertujuan untuk menguji potensi teh hijau pada ginjal mencit yangdiberi MSG. Lama penelitian adalah 30 hari menggunakan hewan uji mencitjantan strain Balb/c. Penelitian ini menggunakan rancangan acak lengkap (RAL)faktorial. Tiap perlakuan terdiri dari P0 sebagai kontrol yang diberi akuades 0,5ml/bb/hr, P1 yang diberi teh hijau 0,015 gr/bb /hari, P2 yang diberi MSG 0,84gr/bb/hr, P3 yang diberi MSG 0,84 gr/bb/hr dan teh hijau 0,015 gr/bb/hr. Hasilpenelitian menunjukkan bahwa pemberian MSG dosis 0,084 gr/bb/hr mampumenurunkan bobot ginjal dan meningkatkan diameter glomerulus

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Tan, Suriyani, Machrumnizar Machrumnizar, and Muhamad Andanu Yunus Slamet. "Monosodium Glutamat (MSG) dan Gambaran Histologis Otak: Implikasi terhadap Pembentukan Otak Mencit." Sanus Medical Journal 5, no. 1 (2023): 1–9. http://dx.doi.org/10.22236/sanus.v5i1.11335.

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Abstract BACKGROUND The sodium salt of glutamic acid, monosodium glutamate (MSG), is a white crystalline compound (glutamic acid). MSG was first produced in large quantities in early 1963 by Korea and Japan which then spread to other countries, including Indonesia. The medical profession is concerned about the detrimental consequences of MSG because of its widespread and uncontrolled consumption. The histological differences between the cerebellum of MSG-treated and MSG-free rats are of interest to researchers. METHOD The Post Test-Only Control Group design was used in this study and used data

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Elefteriou, Florent, Shu Takeda, Xiuyun Liu, Dawna Armstrong, and Gerard Karsenty. "Monosodium Glutamate-Sensitive Hypothalamic Neurons Contribute to the Control of Bone Mass." Endocrinology 144, no. 9 (2003): 3842–47. http://dx.doi.org/10.1210/en.2003-0369.

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Abstract Using chemical lesioning we previously identified hypothalamic neurons that are required for leptin antiosteogenic function. In the course of these studies we observed that destruction of neurons sensitive to monosodium glutamate (MSG) in arcuate nuclei did not affect bone mass. However MSG treatment leads to hypogonadism, a condition inducing bone loss. Therefore the normal bone mass of MSG-treated mice suggested that MSG-sensitive neurons may be implicated in the control of bone mass. To test this hypothesis we assessed bone resorption and bone formation parameters in MSG-treated mi

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Mohammad Kutub Ali and Derron Ricardo Taite. "Monosodium glutamate disrupts zebrafish sleep-like state likely through activation of peripheral nervous system glutamate receptors." World Journal of Advanced Pharmaceutical and Life Sciences 7, no. 1 (2024): 034–43. http://dx.doi.org/10.53346/wjapls.2024.7.1.0034.

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Monosodium glutamate (MSG), a widely used flavor enhancer, has raised concerns about its effects on behavior and sleep. This study investigates how MSG influences zebrafish sleep-like state (SLS) and interacts with other substances affecting neurobehavioral responses. Adult zebrafish were exposed to MSG at concentrations of 50, 100, and 150 mg/L, and their swimming speeds and SLS durations were recorded over a 14-hour night period. The results indicated that higher MSG concentrations increased swimming speeds and decreased SLS duration, suggesting heightened excitability and reduced sleep reco

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Gbore, Francis A., Olubu R. Olumomi, Irewole M. Aworetan, and Ruth A.O. Gabriel-Ajobiewe. "Oral administration of monosodium glutamate alters growth and blood parameters in female rabbits." European Journal of Biological Research 6, no. 3 (2016): 218–25. https://doi.org/10.5281/zenodo.150297.

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Thirty-two female rabbits were used to evaluate the impact of varied doses of aqueous solution of monosodium glutamate (MSG) - a food additive, on growth performance and blood parameters in cross-bred rabbits. The rabbits were randomly assigned into four groups of eight rabbits each. Group 1 received no MSG, group 2 received 1 mg, group 3 received 2 mg, and group 4 received 4 mg per kg body weight of 40% aqueous solution of MSG every 48 hrs for nine weeks, constituting the control, low, medium and high dose groups, respectively. At the end of nine weeks of MSG administration, blood samples wer

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Fortuna, Aliza Dewi. "Effect Of Exposure Of Monosadium Glutamate (MSG) on Viability Of Monocyte Cells." Journal of Stem Cell Research and Tissue Engineering 5, no. 2 (2022): 52. http://dx.doi.org/10.20473/jscrte.v5i2.33144.

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The consumption rate of Monosodium Glutamate (MSG) in Indonesia has increased every year. Uncontrolled use of MSG in Indonesia for a long period of time can cause toxic effects on the body. The free glutamate content produced by MSG can affect the work of the immune system, especially in the innate immune system and cause oxidative stress. To determine the effect of exposure to Monosodium Glutamate (MSG) on the viability of monocyte cells. This study is a laboratory experimental in vitro with a post test only control group design. A total of 10cc of peripheral venous blood was isolated using t

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Mayani, Olvita, Indah Nur Fauziah, Anggi Rehulina Sitepu, et al. "EMBRYOTOXIC AND TERATOGENIC EFFECTS OF MONOSODIUM GLUTAMATE AND SACCHARIN ON WADER (Rasbora lateristriata) FISH." Suranaree Journal of Science and Technology 31, no. 6 (2025): 030243(1–9). https://doi.org/10.55766/sujst-2024-06-e04047.

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The widespread utilization of food additives has garnered increasing attention owing to the safety implications. The continuous reassessment of potential toxicogenic and teratogenic risks associated with food additives is imperative. Monosodium glutamate (MSG) and saccharin, which are prevalently used in the food industry, were the focus of this study. This research aimed to evaluate the effects of MSG, saccharin, and the MSG-saccharin combination on the embryos of wader (Rasbora lateristriata) fish. Observations were conducted at 24, 48, and 72 h postfertilization (hpf) following substance ad

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Pribadhi, Adhitya Naufal, Endang Kusdiyantini, and Rejeki Siti Ferniah. "ISOLASI DAN KARAKTERISASI BAKTERI ASAM LAKTAT DARI PANGAN FERMENTASI CINCALOK SEBAGAI PENGHASIL GAMMA-AMINOBUTYRIC ACID." Jurnal Bioteknologi & Biosains Indonesia (JBBI) 8, no. 1 (2021): 25–32. http://dx.doi.org/10.29122/jbbi.v8i1.3906.

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Isolation and Characterization of Lactic Acid Bacteria from Fermented Food Cincalok as Producer of Gamma-Aminobutyric Acid Cincalok is a fermented food originating from West Kalimantan. This study aimed to obtain lactic acid bacterial isolates (LAB) capable of producing gamma-aminobutyric acid (GABA), to characterize the LAB isolates obtained, and to obtain GABA by the Thin Layer Chromatography (TLC) method. Bacterial growth and GABA production was carried out by adding 5% MSG and without MSG, and measured spectrophotometrically. In this study, 4 LAB bacterial isolates were obtained which were

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Hamza, Reham Z., Fawziah A. Al-Salmi, and Nahla S. El-Shenawy. "Evaluation of the effects of the green nanoparticles zinc oxide on monosodium glutamate-induced toxicity in the brain of rats." PeerJ 7 (September 23, 2019): e7460. http://dx.doi.org/10.7717/peerj.7460.

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Background Monosodium glutamate (MSG) is used extensively as a food additive in the diets of many countries around the world. Aim of the study Our aim was to determine the effects of green zinc oxide nanoparticles on MSG-induced oxidative damage, neurotransmitter changes, and histopathological alternation in the cerebral cortexes of rats. Methods MSG was administered orally at two doses of 6 and 17.5 mg/kg body weight. The higher dose was associated with a significant decline in the activities of superoxide dismutase, catalase, and glutathione peroxidase, as well as the levels of brain-derived

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Acikel-Elmas, Merve, Salva Asma Algilani, Begum Sahin, et al. "Apocynin Ameliorates Monosodium Glutamate Induced Testis Damage by Impaired Blood-Testis Barrier and Oxidative Stress Parameters." Life 13, no. 3 (2023): 822. http://dx.doi.org/10.3390/life13030822.

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Background: the aim of this study was to investigate the effects of apocynin (APO) on hormone levels, the blood-testis barrier, and oxidative biomarkers in monosodium glutamate (MSG) induced testicular degeneration. Methods: Sprague Dawley male rats (150–200 g; n = 32) were randomly distributed into four groups: control, APO, MSG, and MSG + APO. MSG and MSG + APO groups were administered MSG (120 mg/kg) for 28 days. Moreover, the APO and MSG + APO groups received APO (25 mg/kg) during the last five days of the experiment. All administrations were via oral gavage. Finally, biochemical analyses

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Rahmadani, Nurul, Husnarika Febriani, and Melfa Aisyah Hutasuhut. "Effect etanol extract of senduduk leaves (melastoma malabathricum L.) On SGPT and SGOT levels in white rats induced with Monosodium Glutamate." International Journal of Ecophysiology 7, no. 1 (2025): 66–78. https://doi.org/10.32734/ijoep.v7i1.20217.

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The use of Monosodium Glutamate (MSG) has caused a lot of controversy because people think that overuse of MSG may have adverse effects on health. Prolonged consumption of MSG and excessive amounts can cause an imbalance between antioxidants that will disrupt liver function characterised byeinicreased lievelseoif !iSer.um Gliutamic Oxialoacetic Train.saminasee (Si.G.OT) and Seirum Gilutamic PyiruvateeTra.nsiaminasee (SiG.PT) in the bloodstream. The negative effects of MSG can be prevented by reducing MSG consumption and utilising herbal plants such as senduduk leaves. This experiment wants to

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Saraswati, Made Mita Dwi, and Hardinsyah Hardinsyah. "PENGETAHUAN DAN PERILAKU KONSUMSI MAHASISWA PUTRA TINGKAT PERSIAPAN BERSAMA IPB TENTANG MONOSODIUM GLUTAMAT DAN KEAMANANNYA." Jurnal Gizi dan Pangan 7, no. 2 (2016): 111. http://dx.doi.org/10.25182/jgp.2012.7.2.111-118.

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<p>ABSTRACT</p><p>The aim of this study was to analyze the knowledge and consumption behaviour of the first year boy students of IPB on Monosodium Glutamate (MSG) and its safety. Data were collected using self administered questionnaire. Questionnaires were given to the students through cooperation with one of internal club in IPB’s Dormitory. There were 1 324 questionnaires that were given, but only 808 questionnaires were collected back and 24 of them not filled out completely. Thus there were 784 questionnaires that qualified to be research data. Knowledge on MSG and its s

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Brant, B. J., Y. Yu, A. E. Lomax, S. Vanner, and C. J. Tuck. "A102 MONOSODIUM GLUTAMATE INCREASES VISCERAL SENSITIVITY IN A MURINE MODEL OF IRRITABLE BOWEL SYNDROME." Journal of the Canadian Association of Gastroenterology 3, Supplement_1 (2020): 118–19. http://dx.doi.org/10.1093/jcag/gwz047.101.

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Abstract Background Over 70% of patients suffering from symptoms of the irritable bowel syndrome (IBS) report that food is the most common trigger. Patients have identified that monosodium glutamate (MSG) is one food component that they suspect can trigger symptoms, but this remains unproven. As a first step towards establishing a potential role, we sought to examine whether there was a plausible mechanism of how MSG ingestion could underlie exaggerated pain signaling in IBS. Aims To examine the effects of MSG on visceral sensitivity in a murine model of IBS. Methods Balb/c mice were subjected

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Nwanneka, Ofodile Lauretta, Abraham Abigail, Ayoade Yemisi, et al. "Effect of the Aqueous Extract of Ganoderma lucidum on the Haematology, Oestradiol, Cholesterol and Protein Levels of Wistar Rats Fed with Monosodium Glutamate." Malaysian Journal of Pharmaceutical Sciences 18, no. 2 (2020): 47–62. http://dx.doi.org/10.21315/mjps2020.18.2.4.

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Monosodium glutamate (MSG) at high concentration has been reported to alter the physiological and biochemical states of animals and humans. Ganoderma lucidum (G. lucidum) is a polypore mushroom reported to possess many medicinal attributes such as anticholesterolemia and the control of hormonal disorders. The present study investigated the effect of water extract of G. lucidum in the changes of haematology, oestradiol, cholesterol and protein levels of Wistar rats induced by MSG. Haematological analysis was determined from plasma, while oestrogen, serum total protein and cholesterol levels wer

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Dewi Fortuna, Aliza. "PENGARUH PAPARAN Monosodium Glutamat (MSG) TERHADAP VIABILITAS SEL MONOSIT." Analis Kesehatan Sains 11, no. 1 (2022): 8–13. http://dx.doi.org/10.36568/anakes.v11i1.78.

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Angka konsumsi Monosodium Glutamat (MSG) di Indonesia terus mengalami kenaikan tiap tahunnya. Penggunaan MSG yang tidak terkontrol di Indonesia dalam jangka waktu panjang dapat menyebabkan efek toksik bagi tubuh. Kandungan glutamat bebas yang dihasilkan MSG dapat mempengaruhi kerja sistem imun terutama pada sistem imun bawaan serta menyebabkan stress oksidatif. Sehingga tujuan penelitian ini menganalisis pengaruh paparan Monosodium Glutamat (MSG) terhadap vibilitas sel monosit. Penelitian ini merupakan eksperimental laboratoris in vitro dengan rancangan Post test only control group design. Seb

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Baciu, Dora Domnica, Andreea Matei, and Teodor Visan. "Extraction Procedure and Cyclic Voltammetry Assay for Detection of Monosodium Glutamate from Different Processed Food Sources." Revista de Chimie 71, no. 8 (2020): 63–71. http://dx.doi.org/10.37358/rc.20.8.8279.

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In this paper, the possibility of direct electrochemical detection of monosodium glutamate (MSG) from food products by the means of cyclic voltammetry is studied. There are four types of processed food included in this study: bologna sausage, frankfurter hot dogs, hot dogs with cheese, and vegetable soup concentrate cubes. The article describes the procedure of MSG extraction from these products. The MSG (as L-glutamic acid) content was precisely determined using an enzymatic spectrophotometry kit provided by Megazyme. Cyclic voltammetry (CV) experiments were performed using three types of scr

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Rofiqoh, Siti, Dwi Indarti, and Bambang Piluharto. "Effect of Addition of Monosodium Glutamate (MSG) on Coagulation Basin to Characteristics of Cellulose Acetate Membranes." Jurnal ILMU DASAR 17, no. 2 (2017): 83. http://dx.doi.org/10.19184/jid.v17i2.2687.

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The aim of recearch is study the effect of MSG in coagulation basin on cellulose acetat membranes properties. It was preparated by phase inversion technique. As the result showed that the higher the concentration of MSG in coagulation basin, which is character of membrane permeability coefficients and lower water flux. Dextran rejection of 11, 40, 100-200, and 500 kDa increased. The morphology analysis has shown that sub layer membranes structure with 2% MSG addition more uniform than 0,5% MSG addition.Keywords: cellulose acetat, phase inversion, MSG, coagulation basin

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