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Axelsson, Tobias. "Diagnosis System Conceptual Design Utilizing Structural Methods : Applied on a UAV’s Fuel System." Thesis, Linköping University, Department of Electrical Engineering, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2498.
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To simplify troubleshooting and reliability of a process, a diagnosis system can supervise the process and alarm if any faults are detected. A diagnosis system can also identify one, or several faults, i.e. isolate faults, that may have caused the alarm. If model-based diagnosis is used, tests based on observations from the process are compared to a model of the process to diagnose the process. It can be a hard task to find which tests to be used for maximal fault detection and fault isolation. Structural Methods require not very detailed knowledge of the process to be diagnosed and can be used to find such tests early in the design of new processes. Sensors are used to get observations of a process. Therefore, sensors placed on different positions in the process gives different possibilities for observations. A specific set of sensors are in this work called a sensor configuration.
This thesis contributes with a method to predict and examine the fault detection and fault isolation possibility. By using these two diagnosis properties, a suitable sensor configuration is computed and tests to be used in a future diagnosis system are suggested. For this task an algorithm which can be used in the design phase of diagnosis systems, and a Matlab implementation of this algorithm are described.
In one part of this work the Matlab implementation and the algorithm are used to study how a model-based diagnosis-system can be used to supervise the fuel system in an Unmanned Aerial Vehicle (UAV).
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Wang, Zailong. "Regression modes and level sets : excess mass approach and PRIM /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.
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Lam, Lee Kit. "Crystallization behavior of polyamide6/montmorillonite/SEBS nanocomposites." access abstract and table of contents access full-text, 2004. http://libweb.cityu.edu.hk/cgi-bin/ezdb/dissert.pl?msc-ap-b21174428a.pdf.
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Thesis (M.Sc.)--City University of Hong Kong, 2004.At head of title: City University of Hong Kong, Department of Physics and Materials Science, Master of Science in materials engineering & nanotechnology dissertation. Title from title screen (viewed on Sept. 1, 2006) Includes bibliographical references.
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Bäckström, Daniel. "Managing and Exploring Large Data Sets Generated by Liquid Separation - Mass Spectrometry." Doctoral thesis, Uppsala University, Analytical Chemistry, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8223.
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A trend in natural science and especially in analytical chemistry is the increasing need for analysis of a large number of complex samples with low analyte concentrations. Biological samples (urine, blood, plasma, cerebral spinal fluid, tissue etc.) are often suitable for analysis with liquid separation mass spectrometry (LS-MS), resulting in two-way data tables (time vs. m/z). Such biological 'fingerprints' taken for all samples in a study correspond to a large amount of data. Detailed characterization requires a high sampling rate in combination with high mass resolution and wide mass range, which presents a challenge in data handling and exploration. This thesis describes methods for managing and exploring large data sets made up of such detailed 'fingerprints' (represented as data matrices).
The methods were implemented as scripts and functions in Matlab, a wide-spread environment for matrix manipulations. A single-file structure to hold the imported data facilitated both easy access and fast manipulation. Routines for baseline removal and noise reduction were intended to reduce the amount of data without loosing relevant information. A tool for visualizing and exploring single runs was also included. When comparing two or more 'fingerprints' they usually have to be aligned due to unintended shifts in analyte positions in time and m/z. A PCA-like multivariate method proved to be less sensitive to such shifts, and an ANOVA implementation made it easier to find systematic differences within the data sets.
The above strategies and methods were applied to complex samples such as plasma, protein digests, and urine. The field of application included urine profiling (paracetamole intake; beverage effects), peptide mapping (different digestion protocols) and search for potential biomarkers (appendicitis diagnosis) . The influence of the experimental factors was visualized by PCA score plots as well as clustering diagrams (dendrograms).
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Wolski, Witold Eryk [Verfasser]. "Analysis of sets and collections of Peptide Mass Fingerprint data / Witold Eryk Wolski." Berlin : Freie Universität Berlin, 2007. http://d-nb.info/1022539523/34.
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Kwong, Chin Fai. "Thermal and structural properties of polyamide/montmorillonite nanocomposites toughened with SEBS." access abstract and table of contents access full-text, 2004. http://libweb.cityu.edu.hk/cgi-bin/ezdb/dissert.pl?msc-ap-b21174416a.pdf.
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Thesis (M.Sc.)--City University of Hong Kong, 2004.At head of title: City University of Hong Kong, Department of Physics and Materials Science, Master of Science in materials engineering & nanotechnology dissertation. Title from title screen (viewed on Sept. 1, 2006) Includes bibliographical references.
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Tressider, Mary E. "Interwar studies of mass communications : envisioning the conduct of social science and a national political life in the United States /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2006/190.pdf.
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Vo, Ba Tuong. "Random finite sets in Multi-object filtering." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2008. http://theses.library.uwa.edu.au/adt-WU2009.0045.
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[Truncated abstract] The multi-object filtering problem is a logical and fundamental generalization of the ubiquitous single-object vector filtering problem. Multi-object filtering essentially concerns the joint detection and estimation of the unknown and time-varying number of objects present, and the dynamic state of each of these objects, given a sequence of observation sets. This problem is intrinsically challenging because, given an observation set, there is no knowledge of which object generated which measurement, if any, and the detected measurements are indistinguishable from false alarms. Multi-object filtering poses significant technical challenges, and is indeed an established area of research, with many applications in both military and commercial realms. The new and emerging approach to multi-object filtering is based on the formal theory of random finite sets, and is a natural, elegant and rigorous framework for the theory of multiobject filtering, originally proposed by Mahler. In contrast to traditional approaches, the random finite set framework is completely free of explicit data associations. The random finite set framework is adopted in this dissertation as the basis for a principled and comprehensive study of multi-object filtering. The premise of this framework is that the collection of object states and measurements at any time are treated namely as random finite sets. A random finite set is simply a finite-set-valued random variable, i.e. a random variable which is random in both the number of elements and the values of the elements themselves. Consequently, formulating the multiobject filtering problem using random finite set models precisely encapsulates the essence of the multi-object filtering problem, and enables the development of principled solutions therein. '...' The performance of the proposed algorithm is demonstrated in simulated scenarios, and shown at least in simulation to dramatically outperform traditional single-object filtering in clutter approaches. The second key contribution is a mathematically principled derivation and practical implementation of a novel algorithm for multi-object Bayesian filtering, based on moment approximations to the posterior density of the random finite set state. The performance of the proposed algorithm is also demonstrated in practical scenarios, and shown to considerably outperform traditional multi-object filtering approaches. The third key contribution is a mathematically principled derivation and practical implementation of a novel algorithm for multi-object Bayesian filtering, based on functional approximations to the posterior density of the random finite set state. The performance of the proposed algorithm is compared with the previous, and shown to appreciably outperform the previous in certain classes of situations. The final key contribution is the definition of a consistent and efficiently computable metric for multi-object performance evaluation. It is shown that the finite set theoretic state space formulation permits a mathematically rigorous and physically intuitive construct for measuring the estimation error of a multi-object filter, in the form of a metric. This metric is used to evaluate and compare the multi-object filtering algorithms developed in this dissertation.
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Sinha, Ritwik. "EFFICIENT CONFIDENCE SETS FOR DISEASE GENE LOCATIONS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1173464878.
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Wong, Tsun Wah. "A study on mechanical properties of high density polyethylene/polystyrene/SBES [i.e. SEBS] polymer blends." access abstract and table of contents access full-text, 2001. http://libweb.cityu.edu.hk/cgi-bin/ezdb/dissert.pl?msc-ap-b21175202a.pdf.
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Thesis (M.Sc.)--City University of Hong Kong, 2001."A dissertation submitted in part-fulfilment of the requirements for the degree of Master of Science of City University of Hong Kong." Title from title screen (viewed on Sept. 4, 2006) Includes bibliographical references.
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Ryttberg, Mattias. "Significance of Fracture Patterns in a Rock Mass during Excavation by Blasting in Bandhagen, Sweden." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-260885.
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When excavating a rock wall by blasting, pre-existing structures in the rock has a strong impact on the stability of the wall. For excavation in Bandhagen in Stockholm, the nature and orientation of the pre-existing geological features, namely fractures, were not taken into consideration before excavation begun. Geological field studies were carried out in order to investigate the possibility of a more favorable outcome than in the Bandhagen case. Mapping conducted in March 2015 was focused on fracture distribution and the results showed two sets of open shear fractures with fresh surfaces. The first set of the fractures cross-cuts the wall with a strike of NNW-SSE and dips between 70°±30°. The second set of fractures strikes WSW-ENE and are almost parallel to the wall (which strikes roughly 65° E) with a dip towards it, ranging between 55°±35°. The two set of fractures intersect with an acute angle of around 80° and due to their orientation, and that one of the sets dip towards the free face of the wall, they create an unfavorable fracture pattern that makes the wall, at parts, very instable in regard to rockfall and rockslide. Fractures within the respective sets dip towards opposite cardinal points and making an acute angle of 50° for set 2 and 70° for set 1 fractures within the own set are interpreted to conjugate. In addition, there is a well-developed folded foliation that change in strike from parallel to perpendicular to the excavated wall. The foliation is aligned to the strike of both of the fracture sets. This has enabled fractures to open parallel to the mica-rich layers in the gneiss which further adds to the unfavorable pattern of fractures that creates rhombohedral unstable blocks in the rock mass. Due to the fracture pattern, sliding and rockfall have been frequent and safety measures such as rock bolts and a wire mesh have been installed to increase the security factor for the wall. During mapping, a general fracture pattern was possible to deduce from mapping of solely an unexcavated, vegetated part of the area. It became clearer though together with the excavated surface of the wall. Several pre-blast measures could have been preformed to limit rockfall and sliding of rock after excavation. Line-drilling could have been used when blasting near the contour of the wall to decrease the blast-induced fractures by the more effective venting of the excess explosion gas. This could have decreased the closely spaced blast-induced fractures that have been mapped on both the crest and the body of the wall. Another measure would have been to install pre-blast reinforcements on the crest of the wall, which could have prevented at least two large rockfalls that have occurred. If the fracture pattern were known before excavation begun and the aforementioned measures would have been considered, the stability of the wall and the first excavation would undoubtedly have been more successful. A proposal for future open face excavations is to thoroughly assess the geological features to, in a preliminary stage of the planning, eliminate the risk for this outcome to occur in the future.Vid uttag av berg genom sprängning för att skapa en bergvägg har strukturerna i berget en stor betydelse för stabiliteten av väggen. Exempel på strukturer i berggrunden som kan orsaka problem vid uttag av berg är sprickor och då speciellt sprickor som stupar mot väggens teoretiska kontur. Dessa sprickor kan orsaka att hela skivor av berg kan glida från väggen. Om dessa sprickor också korsas av andra sprickor kan de tillsammans bilda kilar som stupar ut mot den fria ytan där utschaktning av berg skett. Kilar som dessa som förekommer på krönet av bergväggen faller ofta ut från väggen och kan vara både farliga för de som utför arbetet samtidigt som de kan göra block runtomkring dem mer instabila. För en utschaktning av berg i Bandhagen, Stockholm togs inte sprickmönstret in i planeringen inför hur sprängning skulle utföras. Detta ledde till att sprängningen som utfördes orsakade mycket glidningar av block och utfall från krönet. Det har lett till att projektet blivit försenat och budgeten överskridits för att korrigera de misstag som gjorts. Korrigeringarna har varit nödvändiga för att väggen i slutändan ska nå en säkerhetsfaktor som inte kan orsaka några person- eller materialskador i framtiden. Kartering med fokus på sprickfördelning utfördes i Mars 2015 för att undersöka om sprängningen hade kunnat utföras på ett annorlunda och bättre sätt om sprickmönstret varit känt innan sprängning inleddes. Karteringen visade två korsande spricksystem där ett av spricksystemen stryker parallellt med väggen och även stupar mot den. De två systemen av sprickor bildar block med plan som lutar ut från väggen vilket resulterar i att många utfall av block skett. Med vetskapen om dessa spricksystem, samt övriga sprickor som förekommer i området, hade de utfall av berg som skett kunnat förutsägas och därigenom hade förslag av sprängmetodik kunnat ges för att minska utfall och för att generellt fått en säkrare vägg redan ifrån början. Både sprängning med tätsöm nära den teoretiska konturen av väggen och förförstärkning av krönet av den teoretiska väggen innan första sprängningen hade kunnat leda till en mycket stabilare vägg. Det hade kunnat leda till att projektet inte blivit försenat och att budgeten för projektet tagit hänsyn till de problem som skulle kunna uppstå. Ett förslag för uttag av berg för bergsslänter är att de geologiska förhållandena ska undersökas mer noggrant, för att i ett tidigt skede upptäcka liknande strukturer i berget och utifrån dessa eliminera risken för att liknande problem uppstår i framtiden.
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Hill, Carla. "Mass assignments for inductive logic programming." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325748.
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Shrestha, Binaya Kumar. "Passive mass transport for direct and quantitative SERS detection using purified silica encapsulated metal nanoparticles." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1904.
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This thesis focuses on understanding implications of nanomaterial quality control and mass transport through internally etched silica coated nanoparticles for direct and quantitative molecular detection using surface enhanced Raman scattering (SERS). Prior to use, bare nanoparticles (partially or uncoated with silica) are removal using column chromatography to improve the quality of these nanomaterials and their SERS reproducibility. Separation of silica coated nanoparticles with two different diameters is achieved using Surfactant-free size exclusion chromatography with modest fractionation. Next, selective molecular transport is modeled and monitored using SERS and evaluated as a function of solution ionic strength, pH, and polarity. Molecular detection is achieved when the analytes first partition through the silica membrane then interact with the metal surface at short distances (i.e., less than 2 nm). The SERS intensities of unique molecular vibrational modes for a given molecule increases as the number of molecules that bind to the metal surface increases and are enhanced via both chemical and electromagnetic enhancement mechanisms as long as the vibrational mode has a component of polarizability tensor along the surface normal. SERS signals increase linearly with molecular concentration until the three-dimensional SERS-active volume is saturated with molecules. Implications of molecular orientation as well as surface selection rules on SERS intensities of molecular vibrational modes are studied to improve quantitative and reproducible SERS detection using internally etched Ag@Au@SiO2 nanoparticles. Using the unique vibrational modes, SERS intensities for p-aminothiophenol as a function of metal core compositions and plasmonics are studied. By understanding molecular transport mechanisms through internally etched silica matrices coated on metal nanoparticles, important experimental and materials design parameters are learned, which can be subsequently applied to the direct and quantifiable detection of small molecules in real samples without the need for lengthy separations and assays.
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Ternes, David Richard. "Building large sets of haptic icons : rhythm as a design parameter, and between-subjects MDS for evaluation." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/32268.
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Haptic icons (brief, tactile stimuli with associated meanings) are a useful new way to
convey information through the modality of touch, but they are difficult to create because
of our lack of understanding into what makes good haptic stimuli and how people will
perceive them. This thesis aims to enlarge our capabilities to design and evaluate haptic
icons, despite these problems. We seek to do this via two overlapping threads of research.
In the first thread, we introduce the design parameter of rhythm as a means of extending
the expressive capabilities of the simple tactile stimuli used in haptic icons. This allows
us to create a set of expressive and perceptually distinguishable haptic stimuli larger by
almost an order of magnitude than any previously created. In the second thread of
research, we tackle the problem of how to evaluate the perceptual characteristics of such
a large set of stimuli with real people. We develop a means of evaluation that allows us to
collect perceived difference data by present each user with only a subset of the total
stimulus collection, and then stitch together an aggregate picture of how the stimuli are
perceived via data collected from overlapping subsets from different users.
To advance these two threads of research, two user studies are run in order to examine
how our haptic stimulus set is perceived and to validate our new method of gathering
perceptual difference data. One study uses an established but cumbersome technique to
study our stimulus set, and finds that haptic rhythms are perceived according to several
different aspects of rhythm, and that users can consistently differentiate between haptic
stimuli along these aspects. The second study uses our newly developed data collection
method to study the same stimulus set, and we find that the new technique produces
results that show no significant difference from the established technique, but using a
data collection task that is much quicker and less arduous for users to perform. We
conclude by recommending the use of our new haptic stimulus set and evaluation
technique as a powerful and viable means of extending the use of haptic icons to larger
sets.Science, Faculty of
Computer Science, Department of
Graduate
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Pais, Preema R. "Reducing background in the t neutrino mass limiting decay t [plus or minus] --> K [plus or minus] Ks̳p0̳̳vt̳ /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2006/174.pdf.
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Alves, Carlos Augusto Silveira. "O caminho das miss?es e seus peregrinos : nova modalidade de produto tur?stico na regi?o das miss?es." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/4751.
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Previous issue date: 2007-08-23A disserta??o tem como objeto de estudo o turismo na regi?o das miss?es, localizada a noroeste do Estado do Rio Grande do Sul, focando, especialmente, um novo produto tur?stico: o Caminho das Miss?es, uma rota de turismo a p? efetuada por peregrinos. O trabalho ? um estudo de caso, baseado numa pesquisa de campo, a partir da realiza??o de observa??o participante, entrevistas gravadas e aplica??o de question?rios com os s?cios da empresa mantenedora do Caminho das Miss?es, os prestadores de servi?os de hospedagem e alimenta??o, os agentes p?blicos do turismo regional e dirigentes cat?licos envolvidos com o produto tur?stico. O Caminho das Miss?es tem como caracter?stica o uso de toda a cadeia produtiva do turismo, envolvendo as ?reas de hospedagem, alimenta??o, artesanato local, entre outras atividades econ?micas da regi?o. Estruturado em tr?s cap?tulos, o trabalho analisa a formata??o, as estrat?gias de venda e a constru??o da identidade do produto tur?stico Caminho das Miss?es, num contexto local em que o turismo passa a ser tratado pelos agentes pol?ticos e privados como op??o para o desenvolvimento regional. Reconstitui a narrativa hist?rica das miss?es, seus s?mbolos, cren?as e pr?ticas religiosos e, em seguida, analisa sua reapropria??o e ressignifica??o pelos empreendedores do referido produto tur?stico. Analisa a apropria??o e recria??o da identidade missioneira a partir da configura??o do produto tur?stico Caminho das Miss?es em turismo cultural, m?stico e religioso. Nesse intento, investiga os conflitos e diverg?ncias entre os agentes p?blicos do turismo e os mentores e empres?rios do neg?cio. Discorre sobre o papel dos prestadores de servi?os, o perfil social dos clientes - os chamados peregrinos - e sua avalia??o dos diferentes aspectos do produto. Por fim, analisa o produto no quadro de uma proposta de desenvolvimento sustent?vel do turismo atrav?s de quatro eixos reflexivos: econ?mico, pol?tico, social e hist?rico-cultural
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Wu, Jiawei. "Physical Properties of Blends of Triblock Copolymer (SEBS) with Low Molar Mass Liquid Crystals." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1434368185.
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Flores, López Alí Eduardo, and López Alí Eduardo Flores. "Aplicación del método Lean-Seis Sigma en el control del almacén de materiales auxiliares de la empresa MSD salud animal." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2016. http://hdl.handle.net/20.500.11799/66482.
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En el presente trabajo se plantea reducir el nivel de inventario de materiales auxiliares, aplicando como herramienta de mejora Lean Seis Sigma. Se desarrollan las etapas de definición, medición, análisis, mejora y control, utilizando herramientas de Manufactura Esbelta y Seis Sigma.
En la fase de definición se puntualiza el problema principal del almacén de materiales auxiliares, dando como principal problema el alto nivel de inventario generado por el desconocimiento del consumo real de materiales en producción. Además, se elabora el Project Charter, los diagramas SIPOC, el plan de comunicación y actualizaciones y el análisis de los interesados.
En la fase de medición en descrito y documentado el estado actual del proceso a mejora, se colecto la información detallada de la voz del cliente que en este caso son los procesos de producción y se valida el sistema de medición (vales de requisición de material).
En la fase de análisis se examina la información colectada relacionada con la voz del cliente (producción) y la voz del proceso (almacén de material auxiliar) para poder identificar la causa raíz de los problemas en procesos, la capacidad de los procesos e identificar las oportunidades de mejora a través del uso de las herramientas de Manufactura Esbelta (5´s y Kanban).
En la fase de mejora se implementa 5´s, sistema FIFO y Kanban para obtener el control del almacén, se diseña el estado futuro, se implementan proyectos piloto (tarjetas Kanban verdes y rojas) y se realiza la capacitación al personal sobre los nuevos procedimientos.
En la fase de control se identifican resultados de los proyectos piloto, oportunidades de réplica y se desarrollan planes para la obtención de un almacén único con un flujo de materiales continuo (bajos niveles de inventario).
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Olsson, Elin. "Mass Conserving Simulations of Two Phase Flow." Licentiate thesis, Stockholm, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3851.
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David, Constança Youd. "Obesity and socioeconomic gradient." Master's thesis, NSBE, 2013. http://hdl.handle.net/10362/9765.
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A Work Project, presented as part of the requirements for the Award of a Masters Degree in Economics from the NOVA – School of Business and EconomicsThis work project studies the determinants of body weight for Portuguese population with special incidence in the socioeconomic dimension through a comparison between 2006 and 2012. More specifically how is body weight influenced by a set of socioeconomic variables that may vary throughout the years. In other words, we set out to understand if socioeconomic status (SES) is a real contributor regarding weight. This study entails a thorough analysis of these variables with the intention of understand which of them remain significant and have real impact on the weight of a human body. Literature points to a confirmation of this real impact of SES status in the body weight and, according to our results, income represents the strongest variable to explain changes in human body weight, coinciding with previous findings. In quantitative terms, an increase of 250€ in the household net income for 2012 is translated into an increase of 0.272 in the BMI. Data used was provided by National Health Institute (INSA) along with National Institute of Statistics (INE) and also collected through a survey.
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Mocniak, Andrew Louis. "Dynamic Level-2 Cache Memory Locking by Utilizing Multiple Miss Tables." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1463737917.
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FRANCISCONI, LUCILAINE S. "Determinação dos constituintes inorgânicos em plantas medicinais e seus extratos." reponame:Repositório Institucional do IPEN, 2014. http://repositorio.ipen.br:8080/xmlui/handle/123456789/23298.
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Dissertação (Mestrado em Tecnologia Nuclear)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Van, Nieuwenhove Nicolas [Verfasser]. "Last interglacial (MIS 5e) palaeoceanography of the nordic seas based on dinoflagellate cyst assemblages / Nicolas van Nieuwenhove." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019951516/34.
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Toma, Hugo Shisei [UNESP]. "Avaliação da passagem transplacentária e colostral de cobre e seus principais antagonistas em cordeiros e ovelhas da raça Bergamácia." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/89148.
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Objetivou-se avaliar a passagem transplacentária e colostral de cobre e seus principais antagonistas (Zn, S, Fe e Mo) por meio de dosagem sérica e no colostro, em cordeiros e ovelhas da raça Bergamácia. Foram utilizados 20 cordeiros provenientes de parto simples e suas respectivas mães da raça Bergamácia mantidas confinadas a partir de 15 dias antes do parto, alimentadas com silagem de sorgo, ração, feno, sal mineral e água ad libitum. Foram realizadas colheitas de sangue das mães, por venopunção jugular, para extração do soro no momento do parto e do colostro através de ordenha manual (30 mL) nos tempos 0, 24, 48 e 72 horas após o parto. Nos cordeiros foi colhido o sangue para obtenção do soro 0, 24, 48 e 72 horas após o nascimento. Também foram avaliados o peso, temperatura retal, volume globular (VG) e proteína plasmática total (PPT) dos cordeiros recém nascidos até 72 horas.Análises dos níveis de molibdênio, zinco, ferro, enxofre e cobre da silagem de sorgo, feno, sal mineral, ração, soro sanguíneo e colostro foram realizadas por espectofotômetro de absorção atômica. Concluiu-se que os cordeiros apresentaram ao nascimento concentrações séricas de Cu, Zn, S, Fe e Mo semelhante aos das ovelhas, evidenciando a existência de passagem transplacentária de minerais. Houve aumento nas concentrações séricas dos minerais (Cu, Zn, Fe, S e Mo) nos cordeiros após a ingestão do colostro. A concentração sérica de zinco e, sérica e colostral de cobre das mães apresentaram correlação positiva significativa com a concentração de cobre sérica dos cordeiros. O valor médio do índice de massa corporal (IMC) das mães 24 horas após o parto foi 118,55 ± 24,21 e dos cordeiros 24 horas após o nascimento foi 39,48 ± 7,67
The objective was to assess the transplacental and colostral copper and its main antagonists (Zn, S, Fe and Mo) by means of serum and colostrum, in lambs and ewes Bergamácia. We used 20 lambs from simple birth and their mothers Bergamasca kept confined from 15 days before calving, fed sorghum silage, feed, hay, mineral and water ad libitum. Blood samples were collected from mothers by venipuncture jugular extraction of serum at delivery and colostrum by milking (30 mL) at 0, 24, 48 and 72 hours after delivery. In lambs the blood was collected to obtain serum 0, 24, 48 and 72 hours after birth. Were also assessed weight, rectal temperature, packed cell volume (PCV) and total plasma protein (TPP) of newborn lambs within 72 hours. Analysis of levels of molybdenum, zinc, iron, sulfur and copper from sorghum silage, hay, mineral salt diet, blood serum and colostrum were performed by atomic absorption spectrophotometer. It was concluded that the lambs at birth had serum concentrations of Cu, Zn, S, Fe and Mo similar to those of sheep, showing the existence of placental transfer of minerals. There was an increase in serum concentrations of minerals (Cu, Zn, Fe, S and Mo) in the lambs after colostrum ingestion. Serum zinc and copper serum and colostrum of mothers had a significant positive correlation with the copper concentration in serum of lambs. The mean body mass index (BMI) of mothers 24 hours after delivery was 118.55 ± 24.21 and lambs 24 hours after birth was 39.48 ± 7.67
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Saggese, Antonio José. "Imaginando a mulher: Playboy: o pôster e seus desdobramentos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/8/8133/tde-17022014-110045/.
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Este trabalho foca, a passagem da pornografia leve (softcore) de mercadoria artesanal e clandestina a produto indústrial. Essa passagem é parte da implantação da sociedade de consumo e do moderno hedonismo O pôster central da Playboy americana é a imagem mercadoria gráfica mais bem sucedida de todos os tempos, e sua fotografia, codificada, norma social para a luxúria.This work focuses on the passage of the softcore pornography from a clçandestine commodity to a industrial product . This passage happen as a part of the establishment of the consumer society and of the modern hedonism. Playboys centerfold may be considered the more successfull image commodity of all times and its photography, highly codifyed, is a social norm to lust.
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Langlois, Nicolas. "Étude d'un système sensorimoteur à commande neuronale impulsionnelle." Rouen, 2001. http://www.theses.fr/2001ROUES039.
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En s'inspirant du modèle humain, nous avons développé un système de vision associant une structure sensorielle assimilable à une rétine artificielle et une action musculaire impliquant des motoneurones. Notre système utilise à la base le modèle de neurone impulsionnel formulé par Gerstner. Contrairement au modèle classique, les potentiels d'action émis peuvent être complètement asynchrones ouvrant ainsi la voie à de nouvelles possibilités dans le codage de l'information. Dans la perspective d'un processeur neuronal, nous proposons un modèle analogique de neurone dans lequel nous assimilons les potentiels d'action émis à des impulsions de tension calibrées. Nous avons associé à chaque synapse un premier circuit chargé de convertir ces impulsions en impulsions de courant dont l'amplitude est fonction du poids accordé à cette synapse. Un circuit dénommé " circuit somatique " intègre les différentes contributions en courant puis émet, à son tour, des potentiels d'action. Ce neurone électronique possède la propriété de pouvoir traiter des informations ayant à la fois une signification spatiale et temporelle. Nous présentons ensuite notre propre système sensorimoteur. Nous nous sommes inspirés des travaux de Hebb pour modifier en permanence les poids synaptiques de ce système : la règle d'apprentissage que nous proposons est du type punition / récompense et n'affecte que les synapses sollicitées. Parallèlement, nous introduisons un paramètre traduisant l'activité d'une certaine population de cellules sensorielles. Nous avons appliqué notre système sensorimoteur à la simulation de l'attraction du regard : par des mouvements de saccades, ce système s'oriente de lui-même vers un objet fixe et monodimensionnel présent dans son champ de vision, quelles que soient la taille et la position de ce stimulus. Certaines propriétés de notre système comme la tolérance à la défaillance sont étudiées.
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Toma, Hugo Shisei. "Avaliação da passagem transplacentária e colostral de cobre e seus principais antagonistas em cordeiros e ovelhas da raça Bergamácia /." Botucatu : [s.n.], 2011. http://hdl.handle.net/11449/89148.
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Resumo: Objetivou-se avaliar a passagem transplacentária e colostral de cobre e seus principais antagonistas (Zn, S, Fe e Mo) por meio de dosagem sérica e no colostro, em cordeiros e ovelhas da raça Bergamácia. Foram utilizados 20 cordeiros provenientes de parto simples e suas respectivas mães da raça Bergamácia mantidas confinadas a partir de 15 dias antes do parto, alimentadas com silagem de sorgo, ração, feno, sal mineral e água ad libitum. Foram realizadas colheitas de sangue das mães, por venopunção jugular, para extração do soro no momento do parto e do colostro através de ordenha manual (30 mL) nos tempos 0, 24, 48 e 72 horas após o parto. Nos cordeiros foi colhido o sangue para obtenção do soro 0, 24, 48 e 72 horas após o nascimento. Também foram avaliados o peso, temperatura retal, volume globular (VG) e proteína plasmática total (PPT) dos cordeiros recém nascidos até 72 horas.Análises dos níveis de molibdênio, zinco, ferro, enxofre e cobre da silagem de sorgo, feno, sal mineral, ração, soro sanguíneo e colostro foram realizadas por espectofotômetro de absorção atômica. Concluiu-se que os cordeiros apresentaram ao nascimento concentrações séricas de Cu, Zn, S, Fe e Mo semelhante aos das ovelhas, evidenciando a existência de passagem transplacentária de minerais. Houve aumento nas concentrações séricas dos minerais (Cu, Zn, Fe, S e Mo) nos cordeiros após a ingestão do colostro. A concentração sérica de zinco e, sérica e colostral de cobre das mães apresentaram correlação positiva significativa com a concentração de cobre sérica dos cordeiros. O valor médio do índice de massa corporal (IMC) das mães 24 horas após o parto foi 118,55 ± 24,21 e dos cordeiros 24 horas após o nascimento foi 39,48 ± 7,67Abstract: The objective was to assess the transplacental and colostral copper and its main antagonists (Zn, S, Fe and Mo) by means of serum and colostrum, in lambs and ewes Bergamácia. We used 20 lambs from simple birth and their mothers Bergamasca kept confined from 15 days before calving, fed sorghum silage, feed, hay, mineral and water ad libitum. Blood samples were collected from mothers by venipuncture jugular extraction of serum at delivery and colostrum by milking (30 mL) at 0, 24, 48 and 72 hours after delivery. In lambs the blood was collected to obtain serum 0, 24, 48 and 72 hours after birth. Were also assessed weight, rectal temperature, packed cell volume (PCV) and total plasma protein (TPP) of newborn lambs within 72 hours. Analysis of levels of molybdenum, zinc, iron, sulfur and copper from sorghum silage, hay, mineral salt diet, blood serum and colostrum were performed by atomic absorption spectrophotometer. It was concluded that the lambs at birth had serum concentrations of Cu, Zn, S, Fe and Mo similar to those of sheep, showing the existence of placental transfer of minerals. There was an increase in serum concentrations of minerals (Cu, Zn, Fe, S and Mo) in the lambs after colostrum ingestion. Serum zinc and copper serum and colostrum of mothers had a significant positive correlation with the copper concentration in serum of lambs. The mean body mass index (BMI) of mothers 24 hours after delivery was 118.55 ± 24.21 and lambs 24 hours after birth was 39.48 ± 7.67
Orientador: Simone Biagio Chiacchio
Coorientador: Raimundo Souza Lopes
Banca: Luis Souza Lima de Souza Reis
Banca: Simone Fernandes
Mestre
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Mauritzen, Cecilie. "A study of the large scale circulation and water mass formation in the Nordic seas and Arctic ocean." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/59864.
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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, and the Woods Hole Oceanographic Institution, 1994.Includes bibliographical references (leaves 205-212).
by Cecilie Mauritzen.
Ph.D.
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Laudernet, Yann. "Approches classiques et quantiques de la solvatation et de la spéciation des ions en solution et en sels fondus chlorés et fluorés." Paris 6, 2002. http://www.theses.fr/2002PA066491.
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Chaker, Juliano. "Corrélations structure/propriétés de conduction ionique dans des matériaux hybrides siloxane-poly(oxydepropylène) dopés par des sels de sodium et de potassium." Paris 11, 2004. http://www.theses.fr/2004PA112190.
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Les matériaux hybrides siloxane-poly(oxyéthylène) (PEO) ou siloxane-poly(oxypropylène) (PPO) obtenus par le procédé sol-gel présentent un grand intérêt scientifique et technologique du fait de l'interpénétration des réseaux inorganique et organique à l'échelle nanométrique. Lorsque ces matériaux hybrides sont dopés avec des sels alcalins, ils présentent une conductivité ionique élevée, similaire aux polymères conducteurs ioniques (10-4 S/cm), tout en présentant des propriétés mécaniques et optiques bien meilleures. Une des limitations de tous ces matériaux est le manque de connaissance sur la nature des espèces mobiles (ions libres ou solvatés, paires ou agrégats d'ions) responsables de la conduction. Afin d'améliorer encore les propriétés ioniques, la connaissance de la nature et de la structure locale autour des ions mobiles est donc fondamentale. En d'autres mots, l'objectif de ce travail est d'établir des corrélations entre la structure locale des porteurs de charge (coordinence, sphère de solvatation) et les aspects électriques macroscopiques (conduction ionique). Notre approche consiste donc à analyser l'ordre local autour des sels dissous par les spectroscopies d'absorption de rayons X (XANES, EXAFS), de Raman et de RMN afin de corréler ces mesures aux paramètres de conduction ionique. L'établissement de telles relations structure/propriétés aux différentes échelles spatiales est évidemment un des points clé pour optimiser de tels matériauxSiloxane-poly(oxi propylene) (PPO) or Siloxane-poly(oxi propylene) hybrid materials prepared by the sol-gel route show increasing scientific and technological interest due to its particular structure in which the polymer chains are grafted to the inorganic nanoparticules. When doped within alkaline salts these hybrids present ionic conductivity similar to that of ionic conductive polymers (10-4 S/cm), and both their mechanical and optical properties are improved. However, the nature of the mobile species, are responsible for there conductivity (free ions, ion-pairs, aggregates) is not well established. So that the knowledge of the nature and the local structure around the mobile ions is the challenger to improve the ionic properties. The but of this work was to establish the correlations between the local structure around the charge carriers (coordination shell, solvation sphere) and the macroscopic conductivity. To reach this objective the local structure was probed by X ray absorption (XANES and EXAFS), Raman and NMR spectroscopy and the results related to that obtained from conductivity measurements
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Schmidt, Eduardo Morgado 1984. "Espectrometria de massas por FT-ICR e Orbitrap : química forense, análise de petróleo e seus derivados." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/248712.
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Orientadores: Marcos Nogueira Eberlin, Alexandra Christine Helena Frankland SawayaTese (doutorado) - Universidade Estadual de Campinas, Instituto de Química
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Resumo: A espectrometria de massas é uma técnica analítica que atualmente permite desde a análise de um único íon molecular até um perfil da distribuição de íons em amostras complexas. Isso vem sendo possível por meio da análise direta com diferentes fontes de ionização e também ao desenvolvimento de analisadores de massas de altíssima resolução tais como o FT-ICR e Orbitrap. Para amostras complexas como o petróleo a fonte de ionização mais adequada para análise dos compostos polares é o Eletrospray (ESI) devido a sua estabilidade e consequentemente reprodutibilidade. Uma alternativa foi testada com a fonte ionização V-EASI, no entanto, as respostas obtidas não foram satisfatórias. O analisador de massas FT-ICR foi utilizado para análise direta de petróleo bruto e permitiu monitorar e investigar o petróleo e seus derivados adicionando novas informações desde a exploração até o refino e, ainda, em um aspecto forense como em derrame de petróleo bruto e investigação de diferentes óleos de motor. Nesse trabalho avaliou-se pela primeira vez o analisador MegaOrbitrap (ainda em fase experimental) para análise de petróleo bruto, que se mostrou tão eficiente senão melhor que o já consagrado FT-ICR. Deixando a parte amostras complexas e retornando para a análise de um único íon, em uma abordagem forense, essa técnica permite a caracterização da composição de corantes utilizados na impressão de notas de Real genuínas e falsas, e ainda, de corantes utilizados para marcar notas de real furtadas de caixas eletrônicos quando estes são violados. Sendo assim, esta tese mostra resultados obtidos da análise de petróleo bruto por ambos os analisadores de massa citados, fato esse inédito na literatura, e também resultados de análises forenses de petróleo, notas de Real falsificadas e também com indicio de furto por meio de corantes e resíduos de explosivos
Abstract: Mass spectrometry is an analytical technique that currently allows from the analysis of a single molecular ion to a profile of the distribution of ions in complex samples. This has been possible through direct analysis with different sources of ionization and also the development of ultra-high resolution mass analyzers such as the FT-ICR and Orbitrap. For complex samples such as oil, the most appropriate source of ionization is the electrospray (ESI) due to its stability and consequently reproducibility. Even though an alternative has been tested with the EASI-V ionization source, the responses obtained were not satisfactory. The analyzer FT-ICR mass is already being used for direct analysis of crude oil and allows monitoring and investigating of the crude oil and its derivatives. This new data about polar compounds may be useful to add new information starting from the oil crude exploration until refining. Additionally, it may also be useful in forensic analysis such as in crude oil spills and in the investigation of the compliance of different motor oils (mineral, semi-synthetic and synthetic) with their labels. In this study we have evaluated for the first time the MegaOrbitrap analyzer (still experimental) for crude oil analysis, which has proved to be as effective, if not better than, the widely used FT-ICR. Dealing with the analysis of a single ion in a forensic aspect, this technique allows the characterization of the dye composition used in the actual printing of genuine and counterfeit banknotes, and further, the dyes used to mark Real banknotes stolen from ATMs after they have exploded. Thus, this thesis shows results obtained from crude oil analysis performed by both mass analyzers mentioned, a fact unprecedented in the literature, and also forensic analysis results of oil, derivatives, Brazilian fake banknotes and also banknotes with theft indicators applied by explosives
Doutorado
Quimica Inorganica
Doutor em Ciências
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Almeida, Lucas Macedo. "Morales e o MAS : a construção de uma nova Bolívia e o projeto de perpetuação no poder de seus dirigentes." reponame:Repositório Institucional da UnB, 2017. http://repositorio.unb.br/handle/10482/23760.
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Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Sociais, Departamento de Estudos Latino-Americanos, Programa de Pós-Graduação em Estudos Comparados Sobre as Américas, 2017.Submitted by Raquel Almeida (raquel.df13@gmail.com) on 2017-06-06T16:07:49Z No. of bitstreams: 1 2017_LucasMacedoAlmeida.pdf: 1520140 bytes, checksum: 79b734a53f8e4fcd06e45decb854f952 (MD5)
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A obra analisa a implementação do projeto de poder do MAS e de Evo Morales. A trajetória política recente da Bolívia assemelha-se com a realidade de outros países da região. Morales é um dos últimos representantes da ascensão de lideranças de esquerda na América Latina. O trabalho aponta que Morales não representa um caso clássico de populismo. A identificação é mais similar ao caso de uma liderança popular. A partir de uma análise comparativa das constituições de 1967 e 2009 e as leis eleitorais, não são encontrados elementos significativos que apontem para um enfraquecimento das instituições bolivianas em detrimento do Poder Executivo, conflitando também com a categoria de democracia delegativa. No entanto, somado a um projeto de inclusão de grupos e setores marginalizados da sociedade boliviana, é possível encontrar, também, a criação de dispositivos jurídicos que auxiliem na perpetuação de forças de Evo Morales, em especial o instituto da reeleição e as diversas interpretações dadas sobre o assunto.
The work analyzes the implementation of the power project of MAS and Evo Morales. Bolivia's recent political trajectory closely resembles the reality of other countries in the Latin America. Morales is one of the last representatives of the rise of leftist leaders in the region. The paper points out that Morales does not represent a classic case of populism. Identification is more similar to a popular leadership. From a comparative analysis of the constitutions of 1967 and 2009 and the electoral laws, no significant elements that I found points to a weakening of Bolivian institutions to the detriment of the Executive Power, also conflicting with the category of delegative democracy. However, in addition to a inclusive project of groups and marginalized sectors in Bolivian society, it is possible to find, also, the creation of legal devices that help in the perpetuation of forces of Evo Morales, especially the institute of reelection and the different interpretations given about the subject.
El trabajo analiza la ejecución del proyecto de poder del MAS y Evo Morales. La reciente historia política de Bolivia es muy parecido a la realidad de otros países de la región. Morales es uno de los últimos representantes de líderes de izquierda a sobrevivir en la región. El trabajo señala que Morales no representa un caso clásico de populismo. La identificación es más similar al caso de una dirección popular. A partir de un análisis comparativo de las constituciones de 1967 y 2009 y las leyes electorales no se encuentran elementos significativos que apuntan a un debilitamiento de las instituciones bolivianas a expensas de la rama ejecutiva, también en conflicto con la categoría de democracia delegativa. Sin embargo, añadido a un proyecto de inclusión de los grupos y sectores marginados de la sociedad boliviana, se puede encontrar también la creación de dispositivos legales que ayudan en la perpetuación de las fuerzas de Evo Morales, sobre todo el instituto de la reelección y las diversas interpretaciones dadas sobre el asunto.
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Randriamampandry, Solohery Mampionona. "Stellar masses of star forming galaxies in clusters." University of the Western Cape, 2010. http://hdl.handle.net/11394/3028.
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Magister Scientiae - MScWe determine the stellar mass of star forming galaxies in the X-ray luminous cluster MS 0451.6-0305 at z ∼ 0.54. The stellar masses are estimated from fitting model spectral energy distributions (SEDs) to deep, optical UBRIz observations obtained from WIYN 3.5m telescope and public NIR K-band image from Palomar Observatory telescope. The model SEDs are based on the stellar population synthesis (SPS) model of Bruzual & Charlot (2003) and Conroy et al. (2009) that span a wide range of age, star formation history, Initial Mass Function (IMF), metallicity and dust content. We measure stellar masses for galaxies down to M∗∼2×10⁸M(.) We find a tight correlation between stellar masses derived from the two SPSs. We compare the derived stellar masses to the dynamical masses for a set of 25 star forming galaxies. The dynamical masses are derived from high resolution, spectroscopic observations of emission lines from the DEIMOS spectrograph on the Keck telescope. A strong correlation is seen between the dynamical and stellar mass for the galaxies; and the star forming galaxies show fairly constant ratio between stellar and dynamical mass. When comparing to the field sample of Guzm ́an et al. (2003) of luminous compact blue galaxies, we see an excess of low mass galaxies in the cluster.
South Africa
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Juanes-Vallejo, Clara M. "Engineering design instrumentation for life detection planetary exploration missions." Thesis, Cranfield University, 2011. http://dspace.lib.cranfield.ac.uk/handle/1826/7319.
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The aim of the research documented in this thesis was to explore issues associated with the development of instrumentation for life detection and characterisation in a planetary exploration context. Within this aim, the following objectives had to be achieved: 1. To consider current and near-future single molecule detection (ultra-low lower limit of detection) analytical techniques that would be compatible with development into a Space qualifiable in situ analytical instrument for the detection of biomarkers in a planetary exploration context. 2. To practically consider the consequences of Planetary Protection and Contamination Control on the development of a sample return instrumentation in a planetary exploration context. 3. To consider the implications of flying an in situ instrument on-board a stratospheric balloon platform in order to apply them into a specific planetary exploration mission: In order to achieve the objectives described above, the following work was pursued: A desk-based European Space Agency (ESA) study was carried out which entailed producing a literature review on single molecule detection technologies that had to be validated by the expert community. This was done by organising an International Workshop on Single Molecule Detection Technologies for Space Applications in March 2009 at Cranfield University, UK. The approved technologies then had to be analysed with standard analytical techniques (i.e., tradeoffs) in order to propose a specific technology for development and present its breadboard implementation and test plans at the end of the study. A sample return experiment implementing PP&CC constraints and protocols was designed, built, tested and flown on-board the ESA, Swedish Space Corporation (SSC), Swedish National Space Board (SNSB) and German Space Agency (DLR) BEXUS stratospheric balloon platform. The biological and engineering results obtained from the sample return flight were then analysed and lessons learnt obtained for future flights. Another desk-based study was performed to research future stratospheric balloon platforms for the exploration of Venus’ cloud layer. The in situ instrument previously proposed for the detection of biomarkers for planetary exploration missions was then put forward as a possible payload for a Venusian stratospheric balloon platform and approved by experts during the Venus Exploration Analysis Group (VEXAG) conference held in August 2011 in Washington D.C, USA. The first part of the research involved studying ultra-low lower limit of detection technologies as these have the potential to impact significantly on the technological and scientific requirements of future Space missions. Two systems were proposed: one based on Tandem Mass Spectrometry (with Cylindrical Ion Trap analysers) followed by Surface Enhanced Raman Scattering spectroscopy to create an MS/MS-SERS instrument for the detection of astrobiology biomarkers in Martian regolith, Europan ice and samples from Titan’s hydrocarbon lakes; and a second one as a Stand-Alone SERS system for the detection of biomarkers in Enceladean plumes, Venusian clouds and cometary coma. The second part of the research practically explored the design of instrumentation for stratospheric balloon platforms. CASS•E, the Cranfield Astrobiological Stratospheric Sampling Experiment, was a life detection experiment that aimed to be capable of detecting stratospheric microorganisms. The experiment consisted of a pump which drew air from the Stratosphere through a 0.2 μm collection filter which retained any microorganisms and >0.2 μm particulates present in the pumped air. Due to the expected rarity of microbes in the Stratosphere compared to the known levels of contamination at ground level, Planetary Protection and Contamination Control (PP&CC)constraints were introduced. Therefore PP&CC protocols were followed to implement Space qualified cleaning and sterilisation techniques; biobarrier technology was implemented to prevent re-contamination of the instrument after sterilisation; and cleanliness and contamination was monitored throughout assembly, integration and testing. The third part of the research demonstrated how an instrument from the first part of the study could be proposed as a payload on-board a stratospheric balloon platform with a focused mission context, i.e., a life detection mission for Venus. Therefore, the research concluded with the proposal of a payload for a Venus mission based on SERS technology on-board a stratospheric balloon platform to search for life above or in the mid Venusian cloud cover.
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Alfimov, Vasily. "Accelerator Mass Spectrometry of 36Cl and 129I : Analytical Aspects and Applications." Doctoral thesis, Uppsala universitet, Jonfysik, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4725.
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Two long-lived halogen radionuclides (36Cl, T1/2 = 301 kyr, and 129I, T1/2 = 15.7 Myr) have been studied by means of Accelerator Mass Spectrometry (AMS) at the Uppsala Tandem Laboratory. The 36Cl measurements in natural samples using a medium-sized tandem accelerator (~1 MeV/amu) have been considered. A gas-filled magnetic spectrometer (GFM) was proposed for the separation of 36Cl from its isobar, 36S. Semi-empirical Monte-Carlo ion optical calculations were conducted to define optimal conditions for separating 36Cl and 36S. A 180° GFM was constructed and installed at the dedicated AMS beam line. 129I has been measured in waters from the Arctic and North Atlantic Oceans. Most of the 129I currently present in the Earth's surface environment can be traced back to liquid and gaseous releases from the nuclear reprocessing facilities at Sellafield (UK) and La Hague (France). The anthropogenic 129I inventory in the central Arctic Ocean was found to increase proportionally to the integrated 129I releases from these reprocessing facilities. The interaction and origin of water masses in the region have been clearly distinguished with the help of 129I labeling. Predictions based on a compartment model calculation showed that the Atlantic Ocean and deep Arctic Ocean are the major sinks for the reprocessed 129I. The variability in 129I concentration measured in seawater along a transect from the Baltic Sea to the North Atlantic suggests strong enrichment in the Skagerrak–Kattegat basin. The 129I inventory in the Baltic and Bothnian Seas is equal to ~0.3% of the total liquid releases from the reprocessing facilities. A lake sediment core sampled in northeastern Ireland was analyzed for 129I to study the history of the Sellafield releases, in particular the nuclear accident of 1957. High 129I concentration was observed corresponding to 1990 and later, while no indication of the accident was found. The results of this thesis research clearly demonstrate the uniqueness and future potential of 129I as a tracer of processes in both marine and continental archives.
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Teschner, Claudia [Verfasser]. "Reconstructing the Plio – Pleistocene evolution of the water mass exchange and climate variability in the Nordic Seas and North Atlantic Ocean / Claudia Teschner." Kiel : Universitätsbibliothek Kiel, 2014. http://d-nb.info/1046832271/34.
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Parenti, Ana Flávia da Costa. "A contribuição das universidades de massa para a promoção da mobilidade socioeconômica e cultural de seus concluintes." Pontifícia Universidade Católica de São Paulo, 2017. https://tede2.pucsp.br/handle/handle/20030.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
This work looks to investigate and analyse how much private Universities, hereafter designated as mass and profit-oriented Universities, can contribute for rising social, economic and cultural useful capital for its students. To do that, it´s been discussed the importance of those Universities for the National Education efforts, the evolution of the Brazilian Policies in this branch, the impact of the privatization process in the sector, and the influence of international financial groups migrating to this economic activity, by making acquisitions of Faculties and Universities, turning them into great organizations, precarianess Education by assuming a profit-oriented logic. The empirical data were based on surveys taked with students attending to the Course of Business Administration of an important private University in the East of São Paulo city. This course was chosen because it has the biggest number of students enrolled. It´s been picked up students at the beggining and at the end of the course. Teachers were also surveyed in search for informations about work conditions and the relationship with students in classroom
Este trabalho teve por objetivo investigar e analisar a contribuição das universidades particulares, aqui denominadas de universidades de massa, para a promoção da mobilidade social, econômica e cultural de seus alunos. Para isso, discutiu-se, não só a importância da Universidade na educação nacional e a evolução da educação brasileira nos últimos anos, como também o processo de privatização das universidades e o fenômeno dos grupos financeiros internacionais que “adquirem” faculdades e universidades, transformando-as em grandes conglomerados educacionais, contribuindo, assim, para a precarização da educação superior no país. O levantamento das informações que contribuíram para esse estudo foi realizado a partir da aplicação de questionários aos alunos do curso de Administração em uma Instituição de Ensino Superior privada, localizada na cidade de São Paulo. Também realizamos entrevistas semiestruturadas com os alunos ingressantes no curso (1º e 2º semestre do curso) e com os concluintes (7º e 8º semestres). Professores do curso também responderam um questionário direcionado a levantar informações complementares com relação às condições de trabalho e a forma como as IES particulares de massa tratam seus alunos e professores
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Iakab, Stefania-Alexandra. "Gold-Coated Black Silicon Nanostructured Surfaces for SERS and SALDI-MS Multimodal Imaging of Biological Applications." Doctoral thesis, Universitat Rovira i Virgili, 2021. http://hdl.handle.net/10803/672198.
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La caracterització in situ de la composició molecular dels teixits biològics és indispensable en la investigació clínica, farmacèutica i forense. Les tècniques d’imatge molecular, com l’espectrometria de masses d’imatge i les imatges per espectroscòpia Raman, empren materials nanoestructurats per abordar reptes com la baixa sensibilitat, l’especificitat i la resolució lateral. L’objectiu d’aquesta tesi és dissenyar, fabricar, avaluar i aplicar un substrat nanoestructurat basat en or i silici (que denominem “AuBSi”) compatible amb aplicacions d’espectrometria de masses d’imatges per desorció/ionització per làser assistides per superfície (SALDI-MS) i espectroscòpia Raman intensificada per superfície (SERS). Els resultats demostren que el substrat AuBSi és reproduïble, fàcil de fer servir, rendible i altament fiable. Assegura una fàcil preparació de la mostra i és totalment compatible amb les dues modalitats d’imatge, cosa que permet un enfocament veritablement multimodal. Mostrem que hi ha una unificació entre els formats de dades SALDI i SERS que permet la integració completa del flux de treball de processament d’imatges i el co-registre d’imatges.. S’han provat les capacitats d’obtenció d’imatges del substrat AuBSi en diverses solucions d’estàndards, seccions histològiques de teixit animal (fetge, ronyó i cervell de ratolí) i empremtes dactilars. L’anàlisi multimodal d’empremtes dactilars va destacar les excel·lents capacitats del substrat per acoblar imatges SALDI i SERS, alhora que s’aconsegueix pal·liar les limitacions de cada tècnica. Així doncs, el substrat AuBSi desenvolupat en aquesta tesi facilita els estudis de metabolòmica in situ dirigits i/o no dirigits per a diversos camp com la investigació clínica, medioambiental, forense i farmacèutica.La caracterización in situ de la composición molecular de los tejidos biológicos es indispensable en la investigación clínica, farmacéutica y forense. Las técnicas de imagen molecular, como la espectrometría de masas de imagen y las imágenes por espectroscopia Raman, emplean materiales nanoestructurados para abordar desafíos como la baja sensibilidad, la especificidad y la resolución lateral. El objetivo de esta tesis es diseñar, fabricar, evaluar y aplicar un sustrato nanoestructurado basado en oro y silicio (que denominamos “AuBSi”) compatible con aplicaciones de espectrometría de masas de imágenes por desorción / ionización por láser asistidas por superficie (SALDI-MS) y espectroscopía Raman intensificada por superficie (SERS). Los resultados demuestran que el sustrato AuBSi es reproducible, fácil de usar, rentable y altamente confiable. Garantiza una fácil preparación de la muestra y es totalmente compatible con ambas modalidades de imagen, lo que permite un enfoque verdaderamente multimodal. Mostramos que existe una unificación entre los formatos de datos SALDI y SERS, que permite la integración completa del flujo de trabajo de procesamiento de imágenes y el coregistro de imágenes.Se han probado las capacidades de obtención de imágenes del sustrato AuBSi en varias soluciones de estándares, secciones histológicas de tejido animal (hígado, riñón y cerebro de ratón) y huellas dactilares. El análisis multimodal de huellas dactilares destacó las excelentes capacidades del sustrato para acoplar imágenes SALDI y SERS, al tiempo que se consiguen paliar las limitaciones de cada técnica. Así, el sustrato AuBSi desarrollado en esta tesis facilita los estudios de metabolómica in situ dirigidos y / o no dirigidos para diversos campos como la investigación clínica, medioambiental, forense y farmacéutica.
Characterising in situ the molecular composition of biological tissues is an indispensable tool in clinical, pharmaceutical and forensic research. Imaging modalities such as mass spectrometry imaging and Raman spectroscopy imaging employ nanostructured materials for addressing challenges such as low sensitivity, specificity and lateral resolution. The aim of this thesis is to design, fabricate, evaluate and apply a gold- and silicon-based nanostructured substrate (named AuBSi) compatible with surface-assisted laser desorption/ionization (SALDI) and surface-enhanced Raman spectroscopy (SERS) imaging applications. Results demonstrate that the AuBSi substrate is reproducible, user-friendly, cost effective and highly reliable. It ensures easy sample preparation and is fully compatible with both imaging modalities, enabling a genuine multimodal approach. We show that there is a unification between SALDI and SERS data formats that allows the full integration of the image processing workflow and the straightforward coregistration of images. We tested the imaging capabilities of the AuBSi on several standard solutions, animal tissue sections (mouse liver, kidney and brain) and fingerprints. The multimodal analysis of fingerprints highlighted the excellent capabilities of the substrate to couple SALDI and SERS imaging, while dealing with the challenges of each technique. Thus, the AuBSi substrate developed in this thesis facilitates targeted and/or untargeted in situ metabolomics studies for various fields such as clinical, environmental, forensics, and pharmaceutical research.
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Correa, Jayme Nicolato. "Aspectos de implementação da interface dos programas de aplicação para o protocolo MMS e seus padrões associados : gerenciamento de conexão e exemplo de aplicação." [s.n.], 1990. http://repositorio.unicamp.br/jspui/handle/REPOSIP/260787.
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Orientador:Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica
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Resumo: Este trabalho apresenta os aspectos relacionados à implementação dos servicos de Gerenciamento de Conexão da API ("Application Program Interface") do prot.ocolo MMS ("Manufacturing Message Specificationt"). É parte integrante de um projeto para implementação do Sistema Didático da Aplicação, SISDI-MAP. São apresentados os conceitos relacionados diretamente à API ou ao MMS e seus Padrões Associados. Finalmente, descreve-se um exemplo de utilizacão deste ambiente, através de um Programa de Aplicacão
Abstract: This work presents the implementation of the connection management procedure performed by the MMS Application Interface. It is part of a project called SISDI-MAP (Application Didactic System). The concepts related to the API or the MMS with its Companions Standards are presented. Finally, it is shown an example of use of the environment by means of an Application Program
Mestrado
Automação
Mestre em Engenharia Elétrica
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Santos, Marcelo Filonzi dos. "Redistribuição postmortem de antidepressivos e seus produtos de biotransformação em tecidos biológicos humanos." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-09022015-092617/.
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Os antidepressivos pertencem a uma importante classe de medicamentos investigados na toxicologia forense. Em casos de amostras provenientes de cadáveres, o intervalo entre o óbito e a obtenção da espécie biológica pode proporcionar a redistribuição postmortem destes fármacos. Com o objetivo de elucidar esse fenômeno, métodos analíticos foram desenvolvidos e aplicados utilizando sangue total (ST), humor vítreo (HV) e fígado. Para as amostras de ST e HV, o método de extração escolhido e validado foi a microextração em fase líquida (LPME) trifásica. Fibras ocas constituídas de polipropileno, com a extensão de 8 cm cada, foram tratadas com o solvente orgânico dodecano (fase orgânica), resultando em um membrana com permeabilidade seletiva. No lúmen destas fibras, adicionou-se ácido fórmico 0,1 mol/L (fase aceptora). Em frasco de fundo chato com 5 mL de capacidade, pipetou-se 3,5 mL de NaOH 0,1 mol/L (fase doadora) e 0,5 mL de ST ou HV. Ao término da extração, as amostras foram introduzidas no GC-MS, sem a necessidade de reações de derivatização. O estudo com ST contemplou os antidepressivos amitriptilina (AMI), nortriptilina (NTR), imipramina (IMI), desipramine (DES), clomipramina (CLO), desmetilclomipramina (DMC), fluoxetina (FLU) e norfluoxetina (NFL). Os limites de quantificação para estas substâncias ficaram inferiores aos níveis terapêuticos (20 ng/mL). As médias dos coeficientes de variação intradia e interdia foram, respectivamente, de 9,7 e 9,8%. As curvas de calibração apresentaram linearidade entre as concentrações de 20 até 1200 ng/mL. A validação do parâmetro integridade da diluição assegurou a mensuração de quantidades superiores ao limite apresentado na curva de calibração. O método foi aplicado em sete amostras reais postmortem e em apenas um caso foi observada uma diferença significativa (300%) entre os valores quantificados no ST periférico e central. Os antidepressivos tricíclicos AMI, NTR, IMI e DES foram avaliados no HV e o efeito matriz foi detectado para os dois últimos analitos. O método foi otimizado e validado utilizando solução salina adicionada de AMI e NTR. O limite de detecção igual a 5 ng/mL, foi obtido com a redução da voltagem da fonte de íons do espectrômetro de massa para 50 eV. Coeficientes de variação foram inferiores a 15%. Os procedimentos validados foram aplicados em seis amostras reais de HV. A relação encontrada entre os valores obtidos no ST periférico e HV foi de aproximadamente 0,1. A extração acelerada por solvente (ASE) e, posteriormente, a extração em fase sólida (SPE) foram as técnicas de separação dos analitos da matriz fígado. Ao término das citadas extrações, os antidepressivos foram analisados no GC-MS. Para esta matriz sólida, são necessários mais estudos, pois os valores encontrados nos ensaios analíticos estão em desacordo com as diretrizes utilizadas na validação dos métodos.Antidepressants belong to an important class of drugs investigated in forensic toxicology. In cases of samples from corpses, the interval between death and obtaining the biological specimens can provide the postmortem redistribution of these drugs. Aiming to elucidate this phenomenon, analytical methods were developed and applied using whole blood (WB), vitreous humor (VH) and liver. For samples of WB and HV, the extraction method chosen and validated was the three-phase liquid phase microextraction (LPME). Hollow fibers consist of polypropylene, with a length of 8 cm each were treated with dodecane organic solvent (organic phase) resulting in a membrane with selective permeability. Into the lumen of these fibers was added formic acid 0.1 mol/ L (acceptor phase). In the vial containing 3.5 mL of NaOH 0.1 mol / L (donor phase) was spiked 0.5 ml of biological fluids (WB or VH). Subsequently, the samples were injected in GC-MS without derivatization reactions. The study of the ST included antidepressants amitriptyline (AMI), nortriptyline (NTR), imipramine (IMI), desipramine (DES), clomipramine (CLO), desmethylclomipramine (DMC), fluoxetine (FLU) and norfluoxetine (NFL). The quantification limits for these substances were below the therapeutic levels (20 ng / ml). The mean coefficients of variation and separate intradays were respectively 9.7 and 9.8%. The calibration curves showed linearity between concentrations of 20 to 1200 ng / mL. The validation of the integrity of the dilution parameter assured measurement higher than the limit shown in the calibration curve quantities. The method was applied to seven real postmortem samples and in one case a significant difference (300%) between the measured values in the peripheral and central ST was observed. The tricyclic antidepressants AMI, NTR, IMI and DES were evaluated in VH and the matrix effect was detected in the last two analytes. The method was optimized and validated using saline spiked AMI and NTR. The limit of detection (5 ng/ml) was obtained by reducing the voltage of the ion source of the mass spectrometer 50 eV. Coefficients of variation were below 15%. The procedures were validated in six real samples of HV. The relationship found between the values obtained in the peripheral ST and HV was approximately 0.1. Accelerated solvent extraction (ASE) and subsequently the solid phase extraction (SPE) were the techniques of separation of analytes liver matrix. At the end of the cited extractions, antidepressants were analyzed in GC-MS. To this solid tissue, further studies are needed, because the values found in the analytical tests were not in accordance with the guidelines used in the validation of the methods.
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Riechel, Andrew T. "Force-Feasible Workspace Analysis and Motor Mount Disturbance Compensation for Point-Mass Cable Robots." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5243.
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Cable-actuated manipulators (or 'cable robots') constitute a relatively new classification of robots which use motors, located at fixed remote locations, to manipulate an end-effector by extending or retracting cables. These manipulators possess a number of unique properties which make them proficient with tasks involving high payloads, large workspaces, and dangerous or contaminated environments. However, a number of challenges exist which have limited the mainstream emergence of cable robots. This thesis addresses two of the most important of these issues-- workspace analysis and disturbance compensation.
Workspace issues are particularly important, as many large-scale applications require the end-effector to operate in regions of a particular shape, and to exert certain minimum forces throughout those regions. The 'Force-Feasible Workspace' represents the set of end-effector positions, for a given robot design, for which the robot can exert a set of required forces on its environment. This can be considered as the robot's 'usable' workspace, and an analysis of this workspace shape for point-mass cable robots is therefore presented to facilitate optimal cable robot design. Numerical simulation results are also presented to validate the analytical results, and to aid visualization of certain complex workspace shapes.
Some cable robot applications may require mounting motors to moving bases (i.e. mobile robots) or other surfaces which are subject to disturbances (i.e. helicopters or crane arms). Such disturbances can propagate to the end-effector and cause undesired motion, so the rejection of motor mount disturbances is also of interest. This thesis presents a strategy for measuring these disturbances and compensating for them. General approaches and implementation issues are explored qualitatively with a simple one-degree-of-freedom prototype (including a strategy for mitigating accelerometer drift), and quantitative simulation results are presented as a proof of concept.
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Bowden, Mathew Glen. "An Analysis of the Subjective Socioeconomic Scale among Hispanic Immigrants and Caucasians." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/1302.
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Subjective socioeconomic status (SES) has previously been shown to be correlated with a large number of health measures. In this study, the subjective SES measure is modified and translated to measure childhood SES. The subjective SES scale is examined in a participant's hometown, community, and nation. Both an immigrant Hispanic and a Caucasian sample were studied (31 Hispanic males; 42 Hispanic females; 38 Caucasian males, 40 Caucasians females). Childhood SES was the most significant predictor of self-reported health in both sample groups.
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Lu, Li Rong. "Topology optimization of acoustic metamaterials." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/189362.
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Prado, Maíra do 1983. "Avaliação da interação entre as diferentes substâncias químicas auxiliares utilizadas em endodontia e seus efeitos nas etapas do tratamento endodôntico." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290437.
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Orientador: Brenda Paula Figueiredo de Almeida GomesTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Introdução: O objetivo do presente trabalho foi avaliar a interação entre as diferentes substâncias químicas auxiliares, utilizadas em endodontia, e seus efeitos nas etapas do tratamento endodôntico. Métodos: Soluções de hipoclorito de sódio (NaOCl) a 0,16%, 1%, 2,5% e 5,25%, clorexidina 2% solução e gel, EDTA 17%, ácido cítrico 10% e ácido fosfórico 37% foram utilizadas isoladamente ou associadas entre si na proporção 1:1. As mesmas foram analisadas quimicamente por espectrometria de massa; e microbiologicamente pelo método de difusão em ágar, contra diferentes patógenos. Adicionalmente, foram avaliados onze protocolos de irrigação em relação à formação de smear layer química por microscopia eletrônica de varredura. Por fim, foram avaliados 9 protocolos de irrigação associados a dois diferentes sistemas de obturação, guta-percha/ AH Plus e Resilon/ Real Seal SE, em relação à microinfiltração coronária e à resistência de união da dentina aos materiais obturadores. Resultados: O NaOCl, em todas as concentrações, associado à clorexidina em ambas as formulações, levou à formação de precipitado, assim como a associação entre a clorexidina e o EDTA e entre clorexidina e solução salina. Todas as associações avaliadas apresentaram algum grau de inibição contra os patógenos testados. Irrigação intermediária, com 10 mL de água destilada, entre as soluções de NaOCl e clorexidina, não foram capazes de inibir a formação de smear layer química, assim como irrigações com EDTA e ácido cítrico. Dos diferentes protocolos de irrigação avaliados, aqueles que apresentaram uma irrigação final com solução de clorexidina 2% tiveram níveis reduzidos de microinfiltração coronária. Em relação à resistência de união à dentina, no sistema obturador guta-percha/AH Plus, os grupos em que se utilizou as associações NaOCl/ácido fosfórico e clorexidina/EDTA apresentaram maiores valores de resistência de união, ao passo que no sistema Resilon/Real Seal SE, os maiores valores foram encontrados nos grupos clorexidina/ácido fosfórico. A utilização da clorexidina como irrigante final não afetou negativamente os sistemas obturadores avaliados. Conclusões: A interação entre as substâncias químicas auxiliares pode levar à formação de precipitados. As diferentes substâncias químicas auxiliares, quando associadas, possuem atividade antimicrobiana. Irrigações intermediárias entre as diferentes substâncias químicas auxiliares são necessárias para reduzir ou até mesmo impedir a formação de precipitados, visualizados na superfície dentinária como uma smear layer química. Durante o preparo químicomecânico, as diferentes substâncias químicas auxiliares geram modificações na superfície dentinária que influenciam na microinfiltração coronária e na resistência de união dos sistemas obturadores guta-percha/AH Plus e Resilon/Real Seal SE
Abstract: Introduction: The aim of the present study was to evaluate the interaction among different chemical auxiliary substances used in endodontics and their effects on different steps of endodontic treatment. Methods: 0.16%, 1%, 2.5% and 5.25% sodium hypochlorite solutions (NaOCl), 2% chlorhexidine solution and gel, 17% EDTA, 10% citric acid, 37% phosphoric acid, distilled water, and saline solution were used both associated with each other (1:1 ratio) and not associated. The solutions were chemically examined with mass spectrometry. They were microbiologically examined using the Agar Diffusion Method, against different pathogens. In addition, eleven protocols were analyzed in regards to chemical smear layer with scanning electron microscopy. Finally, nine irrigation protocols (associated with two filling systems, i.e. gutta-percha/AH Plus and Resilon / Real Seal SE) were examinated regarding coronal microleakage and were examined as well regarding their bond strength with dentin. Results: NaOCl, at all concentrations, associated with both chlorhexidine formulations, led to precipitate formation, similar to the association between chlorhexidine/EDTA, and the chlorhexidine/saline solution association. All associations had some degree of inhibition against the evaluated pathogens. Intermediate flush, with 10 mL of distilled water, between NaOCl and chlorhexidine did not inhibit chemical smear layer formation, similar to intermediate flushes with EDTA and citric acid. Among the different irrigation protocols that were evaluated, when final flush with 2% chlorhexidine was present, the lowest levels of coronal microleakage were found. Regarding the bond strength to dentin, in the gutta-percha/AH Plus system, the groups with NaOCl/phosphoric acid and chlorhexidine/EDTA associations showed higher bond strength values. In the Resilon/Real Seal SE system, the highest values were found in the chlorhexidine/phosphoric acid groups. The use of chlorhexidine as a final flush did not negatively affect the filling systems evaluated. Conclusions: The interaction among the auxiliary chemical substances may lead to precipitate formation. The association between the different substances has antimicrobial activity. Intermediate flushes are necessary to reduce or even avoid the formation of chemical smear layer on the dentin surface. During the chemo-mechanical preparation, the various auxiliary chemical substances used do modify the dentine surface. These modifications have influence in the coronal microleakage and in the bond strength of the filling systems gutta-percha/AH Plus and Resilon / Real Seal SE
Doutorado
Endodontia
Doutora em Clínica Odontológica
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Wiedmer, Petra. "Geschlechtsspezifische Körpergewichtsregulation bei Mäusen :Untersuchungen zur Set-point-Theorie der Körpermasse." Phd thesis, Universität Potsdam, 2004. http://opus.kobv.de/ubp/volltexte/2005/182/.
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Entsprechend der sogenannten Set-point-Theorie besitzt jeder Mensch eine individuell festgelegte Körpermasse, die über große Zeiträume konstant gehalten und gegen Abweichungen verteidigt wird. Es wird angenommen, dass der Körper auf noch unbekannte Weise Änderungen in der Körpermasse per se wahrnimmt und daraufhin Mechanismen aktiviert, die zur Regenerierung der ursprünglichen Masse führen.
In dieser Arbeit wurde die Hypothese getestet, dass eine künstliche Erhöhung der Körpermasse zu einer kompensatorischen Reduktion in der Körpermasse führt, um das Ausgangsgewicht wieder zu regenerieren. Die Körpermasse von männlichen und weiblichen Mäusen wurde akut durch die Implantation von Gewichten mit einer Masse von 10% der aktuellen Körpermasse in die Bauchhöhle erhöht. Bei Gültigkeit der Set-point-Theorie sollte die Körpermassereduktion der Masse des zusätzlichen Gewichtsimplantats entsprechen.
Die Mäuse reagierten auf die künstlich erhöhte Körpermasse geschlechtsspezifisch. Männchen zeigten eine partielle Reduktion in der Körpermasse. Weibchen zeigten langfristig jedoch keine Änderungen in der Körpermasse. Die Reduktion der Körpermasse erfolgte bei den Männchen durch eine Abnahme in der Fettmasse. Die fettfreie Masse war in beiden Geschlechtern nicht verändert. Änderungen in der Körpermasse wurden vor allem durch Änderungen in der Energieaufnahme hervorgerufen. Ein Einfluss des Energieumsatzes auf Änderungen in der Körpermasse konnte nicht nachgewiesen werden.
Die Regulation der Körpermasse entsprechend eines massespezifischen Set-points konnte partiell für die Männchen gezeigt werden. Bei den Männchen könnte daher die Wahrnehmung der Körpermasse in die Regulation der Körpermasse teilweise integriert sein. Weibchen verminderten ihre Körpermasse dagegen trotz der künstlichen Körpermasseerhöhung nicht. Das führte zur Bewahrung der Energiereserven und spricht eher für die Regulation der Körpermasse entsprechend des notwendigen Energiebedarfs im Vergleich zu Änderungen in der Körpermasse per se.
Diese Ergebnisse zeigen, dass die Regulation der Körpermasse geschlechtsspezifischen Mechanismen unterliegt. Dementsprechend sind auch geschlechtsspezifische Ansätze zur Therapie von Übergewicht und Adipositas notwendig.The set-point theory of body mass assumes that humans possess an individually determined body mass which is maintained over long periods and which is defended against deviations. It is supposed that the body can perceive changes in body mass per se, this process leading to activation of mechanisms aiming at regeneration of initial body mass. Here the following hypothesis was tested: An artificial increase in body weight leads to a compensatory reduction in body mass in order to regenerate initial body weight. Body mass of male and female mice was acutely increased by implanting weight loads into the abdominal cavity. Additional weights corresponded to 10% of initial body mass. According to the set-point theory we expected the mice to decrease body mass to the extend of the additional weight. A gender-specific response was observed. Males showed a partially reduced body mass. In contrast, females did not show body mass changes in the long-term. Males reduced their body mass at the expense of fat mass. Fat free mass was unchanged in both genders. Changes in body mass were mainly caused by changes in energy intake. An impact of energy expenditure on body mass changes could not be demonstrated. Body mass regulation according to a mass-specific set-point could be partially shown for males. Therefore, in males perception of body mass could be partially integrated in the regulation of body weight. Females did not decrease their body mass despite artificially increased body mass pointing to preservation of their energy depots. This argues for regulation of body mass according to needed energy requirements rather than according to changes in body mass per se. These results show that body mass regulation underlies gender-specific mechanisms. Accordingly, gender-specific approaches are needed for treating overweight and obesity.
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Lopes, Margareth Corrêa Lima. "Crescimento de recém-nascidos pré-termos tardios nos primeiros seis meses de idade corrigida em Cuiabá-MT." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-24102014-125210/.
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Introdução: O nascimento de recém-nascidos pré-termo tardios (RNPT-T), geralmente tratados como \"quase termo\", vem aumentando nas últimas décadas. Vários fatores são atríbuídos à sua etiologia e contribuem para aumentar as taxas de morbimortalidade perinatal e infantil. Atualmente se dispõe de poucos estudos sobre esses recém-nascidos, especialmente sobre o seu crescimento. Objetivos: Analisar o crescimento de RNPT-T nos seis primeiros meses de idade corrigida. Métodos: Estudo observacional, analítico de uma coorte de 64 RNPT-T, coletados nos quatro maiores hospitais de Cuiabá, entre janeiro e setembro de 2013 e acompanhados até 6 meses de idade corrigida. Os dados foram coletados ao nascer, às 40 semanas, 3 e 6 meses de idade corrigida. Foram realizadas análises de correlação entre os parâmetros antropométricos perímetro braquial (PB) e prega cutânea tricipital (PCT) em função dos índices antropométricos PB/PC (perímetro cefálico), peso/comprimento (P/C) e Índice de Massa Corpórea (IMC) e realizada regressão linear múltipla. Resultados: Ao nascimento, 81,3% foram classificados como adequados para a idade gestacional, com a média de peso de 2343,80g ± 430,50. Todos os recém-nascidos apresentaram crescimento contínuo nos seis meses de idade corrigida para os valores de peso, comprimento e perímetro cefálico (PC). Já os valores médios de PCT, de PB/PC e de IMC não mostraram diferença aos 6 meses de idade corrigida. Todos os coeficientes de correlação (r) dos parâmetros PCT e PB em relação aos índices antropométricos apresentaram significância estatística, sendo os valores mais altos para PB versus PB/PC e P/C e menores para PB versus IMC. No modelo final da regressão linear múltipla da PCT, o PB/PC contribuiu significantemente para predizer o depósito de gordura ao nascimento, às 40 semanas e aos 3 meses de idade corrigida (33,8%%, 46,07% e 18,08% respectivamente); aos 6 meses o melhor preditor foi a razão P/C (10,45%). O melhor preditor para o PB foi o PB/PC, que permaneceu no modelo com valores de 73,71%% em todos os tempos avaliados. Conclusão: Os parâmetros peso, comprimento, perímetro cefálico e perímetro braquial e a relação P/C aumentaram nos quatro tempos de aferição, enquanto o PCT e as relações PB/PC e IMC não se modificaram do primeiro para o segundo trimestre e o PB/PC foi o melhor preditor do depósito de gordura subcutânea tricipital (PCT) e de massa gorda e muscular (PB)Introduction: The birth of newborns late preterm (RNPT -T), usually treated as \"near term\", has been increasing in recent decades. Several factors are attributed to its etiology and contribute to increased rates of perinatal and infant morbidity and mortality. Currently there are few studies of these newborns, especially about their growth. Objectives: To analyze the growth pattern of late preterm infants from birth to six months of corrected age. Methods: This cohort study included 64 RNPT-T, in four major hospitals in Cuiabá, between January and September 2013 and followed until 6 months corrected age. Data were collected at birth, at 40 weeks, 3 and 6 months corrected age. Correlation analyzes between anthropometric parameters mid- arm circumference (MAC) and triceps skinfold (TS) on the basis of anthropometric indices MAC / HC (head circumference), weight / length (W / L) and body mass index (BMI) were performed multiple linear regression. Results: At birth, 81.3 % were classified as appropriate for gestational age, with the average weight of 2343.80 ± 430.50 g. All newborns had a continuous growth in the six months corrected age for the values of weight, length and head circumference (HC). The average value of TS values of MAC / HC and BMI showed no difference at 6 months of corrected age. All correlation coefficients (r) of the TS and MAC parameters in relation to anthropometric indices showed statistically significant, with the highest values for MAC versus MAC / HC and W / L and lower for MAC versus BMI. At the end of the TS model of multiple linear regression, the MAC / HC contributed significantly to predict the deposition of fat at birth, at 40 weeks and at 3 months\' corrected age (33.8 %, 46.07 % and 18.08 % respectively); at 6 months was the best predictor of the ratio W/ L (10.45%). The best predictor for the MAC was the MAC / HC, which remained in the model with values of 73.71 % at all evaluated times. Conclusion: The parameters weight, length, head circumference and arm - circumference and the ratio W / L increased in the four times of measurement, while the TS and MUAC / HC relations and BMI did not change from the first to the second quarter and MAC / HC was the best predictor of subcutaneous fat deposit triceps (TS) and fat and muscle (MAC) mass
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Silva, Helber Wagner da. "Um arcabou?o cross-layer para controle de sess?es multiusu?rio com alta demanda de recursos em redes IoT softwarizadas." PROGRAMA DE P?S-GRADUA??O EM SISTEMAS E COMPUTA??O, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24932.
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As aplica??es de miss?o cr?tica (AMC) representam um dos casos de uso mais promissores da Internet das Coisas (do ingl?s, Internet of Things ? IoT) ao prometer impactos em ?reas vitais, como videovigil?ncia inteligente em ambientes com alta densidade humana, tr?fego de ve?culos aut?nomos com seguran?a, cirurgia remota com precis?o, dentre muitas outras. As AMC devem explorar o conte?do disponibilizado por plataformas IoT em cen?rios de rede IoT softwarizada (IoTS), que nesta tese representa um sistema IoT executando sobre uma infraestrutura de rede cuja arquitetura inclui substrato de rede definida por software para permitir a flexibilidade nas opera??es de controle. Entretanto, as AMC possuem fortes requisitos de Qualidade de Servi?o (do ingl?s, Quality of Service - QoS), tais como lat?ncia, jitter e perdas, al?m da alta demanda por recursos de rede (e.g., processamento em n?s, caminhos e largura de banda nos enlaces) que precisam ser assegurados pela IoTS para garantir efici?ncia e precis?o. A variabilidade e a dinamicidade de requisitos dos servi?os nesse cen?rio s?o muito elevadas, que podem ir desde a coleta de dados escalares (e.g., sensores ambientais, etc.) at? o processamento digital de multim?dia (e.g., v?deo e ?udio) em tempo real. Nesse cen?rio de IoTS com AMC sens?vel a QoS, torna-se necess?rio um plano de controle que tenha capacidade de prover um servi?o de transporte mais refinado com qualidade garantida, de forma otimizada e aut?noma. Esta tese vai al?m do estado da arte ao definir um arcabou?o hol?stico para o controle de sess?es multiusu?rios (agregando m?ltiplas AMC compartilhando conte?do de uma plataforma IoT) altamente sens?veis a qualidade em uma IoTS, com m?todos refinados para orquestra??o auto-organizada, controle e gest?o de recursos orientados a QoS. O arcabou?o, chamado CLASSICO (Cross-LAyer SDN SessIon COntrol), permite acoplar a variabilidade e a dinamicidade da IoTS, alocando dinamicamente recursos para satisfazer requisitos das AMC em termos de largura de banda elevada e lat?ncias muito baixas durante todo o tempo de dura??o da sess?o, alavancando substrato das Redes Definidas por Software (do ingl?s, Software Defined Networks - SDN) para flexibilidade e modularidade. Para alcan?ar esses objetivos, CLASSICO define um plano de controle cross-layer integrado ? IoTS que considera os par?metros do conte?do (ao n?vel de aplica??o) requerido pelas AMC para construir e manter sess?es multiusu?rios orientadas a QoS, e induz uma IoTS multiusu?rio otimizada atrav?s do transporte baseado em grupos (ao n?vel de rede), buscando ao mesmo tempo aumentar a escalabilidade do sistema IoT. Para valida??o, CLASSICO foi prototipado e avaliado em um testbed real em um caso de uso de v?deo. Os resultados da avalia??o revelam os ganhos de CLASSICO em termos de QoS e Qualidade de Experi?ncia (do ingl?s, Quality of Experience - QoE), em compara??o a uma solu??o baseada em SDN Multicast.
Mission Critical Applications (AMC) represent one of the most promising use cases in the Internet of Things (IoT) as they promise to impact vital areas, such as smart surveillance in environments with high human density, autonomous vehicle traffic with security, remote surgery with precision, among many others. AMC are expected to exploit the content made available by IoT platforms in softwarized IoT networks (IoTS) scenarios, which represents an IoT system running over a network infrastructure which includes software-defined network substrate to allow flexibility in control operations. However, AMCs have strong Quality of Service (QoS) requirements, such as latency, jitter and losses, as well as the high demand for network resources (e.g., node processing, paths and link bandwidth) that need to be guaranteed by IoTS to ensure efficiency and accuracy. The variability and dynamicity of service requirements in this scenario are very high, ranging from scalar data collection (e.g., environmental sensors, etc.) to digital multimedia (e.g., video and audio) processing in real time. In this IoTS scenario with QoS-sensitive AMC, it is necessary to have a control plan with the capacity to provide a fine-grained transport service with guaranteed quality, in an optimized and autonomous way. This thesis goes beyond the state of the art by defining a holistic framework for controlling multiuser sessions (aggregating multiple AMCs sharing content from an IoT platform) highly quality-sensitive in an IoTS, with fine-grained methods for quality-oriented self-organized orchestration, resource control and management. The framework, called CLASSICO (Cross-LAyer SDN SessIon COntrol), allows to couple IoTS variability and dynamicity, dynamically allocating resources to meet AMC requirements regarding high bandwidth and very low latencies throughout the session duration, leveraging the substrate of the Software Defined Networks (SDN) for flexibility and modularity. To achieve these objectives, CLASSICO defines a cross-layer control plan integrated with IoTS that considers the content parameters (at the application level) required by the AMC to build and maintain QoS-oriented multiuser sessions, and induces an optimized multiuser IoTS through group-based transport (at the network level), while increasing the scalability of the IoT system. For validation purposes, CLASSICO has been prototyped and evaluated on a real testbed in a video use case. The results of the evaluation reveal the gains of CLASSICO regarding QoS and Quality of Experience (QoE), in comparison to an SDN Multicast-based solution.
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Henriet, Charlotte. "Effet d'une carence en soufre combinée à un stress hydrique chez le pois protéagineux : Etude des mécanismes moléculaires mis en jeu dans les organes puits et source au cours de la phase reproductive." Thesis, Bourgogne Franche-Comté, 2019. http://www.theses.fr/2019UBFCK067.
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Le pois (Pisum sativum L.) est une légumineuse qui produit des graines riches en protéines pour l’alimentation humaine et animale et qui, de par sa symbiose avec des bactéries fixatrices d’azote de l’air, enrichit les sols en azote. Le développement plus large de la culture du pois est donc un enjeu agroécologique majeur. Le déficit hydrique combiné à l’appauvrissement des sols en soufre, un macroélément nécessaire aux réactions de défense des plantes, sont deux stress abiotiques qui interagissent dans le contexte actuel de changement climatique. Pourtant, les mécanismes moléculaires sous-jacents à l’adaptation du pois au stress hydrique et leur modulation par la nutrition soufrée restent à élucider. Les objectifs de cette thèse étaient de décrire l’impact d’une interaction entre ces deux stress abiotiques que sont le stress hydrique et la carence en soufre au cours de la phase reproductive sur le rendement et la qualité des graines de pois, puis de caractériser au moyen d’approches omiques les mécanismes moléculaires sous-jacents en se focalisant sur les graines en cours de développement et les feuilles, sources de nutriments pour les graines.Ainsi, des plantes de pois (cv. ‘Caméor’) privées de sulfate deux semaines avant floraison ont été soumises à une période de stress hydrique modéré de neuf jours à partir du début de la floraison. Chaque stress a aussi été appliqué individuellement en parallèle d’une condition standard. L’analyse des plantes à maturité montrent un effet synergique des deux stress simples sur le rendement et les composantes du rendement. En revanche, la composition protéique de la graine, caractérisée par le ratio de globulines 7S/11S, est moins affectée en réponse au double stress qu’en condition de carence en soufre seule, et ne varie pas en réponse au stress hydrique. Ces résultats montrent que le stress hydrique atténue l'effet négatif de la carence en soufre sur la composition protéique des graines. Des résultats identiques ont été obtenus pour le ratio azote/soufre des graines (corrélé au ratio 7S/11S), suggérant qu’il soit un bon indicateur de la composition protéique des graines de pois.Afin de déterminer les mécanismes par lesquels les graines et les feuilles adaptent leur métabolisme dans ces conditions de stress multiples, des graines en développement et les feuilles des deux premiers nœuds reproducteurs ont été prélevées avant l’application du stress hydrique, pendant la période de double stress, et lors du ré-arrosage. Ces tissus ont été soumis à des analyses omiques (protéomique, transcriptomique, ionomique, métabolomique) offrant une vision globale de la réponse des graines et des feuilles aux simples et double stress. Les analyses des graines ont mis en évidence un effet atténué de la carence en soufre combinée au stress hydrique sur le transcriptome et le protéome comparé à une carence en soufre seule. La réponse des graines aux stress simples ou combinés met en jeu un faible nombre de protéines impliquées dans l’élimination des espèces réactives de l’oxygène ou dans le maintien de l’équilibre redox. Dans les feuilles, une reprogrammation transcriptionnelle en réponse au double stress a lieu aux premiers et derniers stades étudiés. Cette reprogrammation fait intervenir des gènes impliqués dans les processus de modifications post-traductionnelles et de transport des protéines. Des changements dans le protéome des feuilles ont lieu à la fin du double stress et lors du ré-arrosage, mettant en lumière des protéines qui jouent un rôle clé dans les processus de détoxification, notamment liés à l’accumulation des métaux.Ces nouvelles connaissances ont permis l’identification de protéines candidates susceptibles de contrôler les mécanismes de développement des graines ou la détoxification des cellules lors de stress abiotiques. Ils offrent des perspectives d’amélioration et de stabilisation des rendements et de la qualité nutritionnelle des graines chez le poisPea (Pisum sativum L.) is a grain legume crop that produces seeds rich in proteins for food and feed and, thanks to its symbiosis with nitrogen-fixing bacteria, enriches the soil with nitrogen. The wider development of pea cultivation is therefore a major agroecological challenge. Water stress combined with sulfur deficiencies in soils (S is a macroelement necessary for plant defense reactions) are two abiotic stresses that interact in the current context of climate change. However, the molecular mechanisms underlying pea adaptation to water stress and their modulation by sulfur nutrition remain to be elucidated. The objectives of this thesis were, first, to describe the impact of an interaction between these two abiotic stresses, water stress and sulfur deficiency, during the reproductive phase on the yield and quality of pea seeds and, second, to characterize using -omics approaches the underlying molecular mechanisms by focusing on developing seeds and leaves, sources of nutrients for developing seeds.Thus, pea plants (cv. ‘Caméor’) deprived of sulfate two weeks before flowering were subjected to a period of nine days of moderate water stress from the beginning of flowering. Each stress was also applied individually in parallel with a non-stressed condition. The analysis of mature plants showed a synergistic effect of the two single stresses on yield and yield components. On the other hand, the protein composition of the seed, characterized by the 7S/11S globulin ratio, was less affected in response to the double stress than in response to sulfur deficiency alone, and did not vary in response to water stress. These results show that water stress mitigated the negative effect of sulfur deficiency on seed protein composition. Similar results were obtained for the seed nitrogen/sulfur ratio (correlated to the 7S/11S ratio), suggesting that it is a good indicator of seed protein composition in pea.In order to determine the mechanisms by which seeds and leaves adapt their metabolism under these multiple stress conditions, developing seeds and leaves of the first two reproductive nodes were collected prior to the application of water stress, during the combined stress period, and during re-watering. These tissues were subjected to omics analyses (proteomics, transcriptomics, ionomics, metabolomics) offering a global view of the response of seeds and leaves to the single and double stresses. The analysis of seeds revealed a mitigated effect of sulfur deficiency combined with water stress on the seed transcriptome and proteome compared to sulfur deficiency alone. The responses of seeds to the single or combined stresses involved a few proteins but these were involved in the removal of reactive oxygen species or in the maintenance of the redox balance. In leaves, transcriptional reprogramming in response to the double stress occurred at the first and last developmental stages studied. This reprogramming involves genes with roles in post-translational modification and protein transport processes. Changes in the leaf proteome occurred at the end of the double stress and during re-watering, highlighting proteins that play a key role in detoxification processes, including metal accumulation.This new knowledge has allowed the identification of candidate proteins for controlling the mechanisms of seed development or detoxification of cells during abiotic stress. They offer prospects for improving and stabilizing pea yields and seed nutritional quality
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Bassler, Christopher Colby. "Analysis and Modeling of Hydrodynamic Components for Ship Roll Motion in Heavy Weather." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/23258.
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Ship roll motion has been the subject of many studies, because of the complexities associated with this mode of ship motion, and its impact on operability, safety, and survivability. Estimation and prediction of the energy transfer and dissipation of the hydrodynamic components, added inertia and damping, is essential to accurately describe the roll motions of a ship. This is especially true for ship operations in moderate to extreme sea conditions. In these conditions, a complex process of energy transfer occurs, which alters the physical behavior of the hydrodynamic components, and ultimately affects the amplitude of ship roll motion. Bilge keels have been used on ships for nearly two centuries, to increase damping and reduce the severity of roll motions experienced by a ship in waves. Because ship motions are more severe in extreme sea conditions, large roll angles may occur. With the possibility of crew injury, cargo damage, or even capsize, it is important to understand the behavior of the roll added inertia and damping for these conditions. Dead ship conditions, where ships may experience excitation from beam, or near beam, seas present a worst case scenario in heavy weather. The behavior of a ship in this condition should be considered in both the design and assessment of seakeeping performance.
In this study, hydrodynamic component models of roll added inertia and roll damping were examined and assessed to be unsuitable for accurate prediction of ship motions in heavy weather. A series of model experiments and numerical studies were carried out and analyzed to provide improved understanding of the essential physical phenomena which affect the hydrodynamic components and occur during large amplitude roll motion. These observations served to confirm the hypothesis that the existing models for roll added inertia and damping in large amplitude motions are not sufficient. The change in added inertia and damping behavior for large roll motion is largely due to the effects of hull form geometry, including the bilge keels and topside geometry, and their interactions with the free surface. Therefore, the changes in added inertia and damping must be considered in models to describe and predict roll motions in severe wave environments.
Based on the observations and analysis from both experimental and numerical methods, several time-domain model formulations were proposed and examined to model hydrodynamic components of large amplitude roll motions. These time-domain formulations included an analytical model with memory effects, a piecewise formulation, and several possibilities for a bilge keel force model. Although a piecewise model for roll damping was proposed, which can improve the applicability of traditional formulations for roll damping to heavy weather conditions, a further attempt was undertaken to develop a more detailed model specifically for the bilge keel force. This model was based on the consideration of large amplitude effects on the hydrodynamic components of the bilge keel force. Both the piecewise and bilge keel force models have the possibility to enable improved accuracy of potential flow-based numerical prediction of ship roll motion in heavy weather. However, additional development remains to address issues for further practical implementation.
Ph. D.
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Truyen, David. "Etude par simulation composant 3D des effets singuliers SEU et SET induits par ions lourds sur le noeud technologique CMOS bulk 180 nm." Montpellier 2, 2007. http://www.theses.fr/2007MON20139.
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