Academic literature on the topic 'MTF'

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Journal articles on the topic "MTF"

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Sunaryo, Sagara Mahardika, Lukas Chrisantyo, and Yuan Lukito. "ANALISIS ALGORITMA MTF, MTF-1 DAN MTF-2 PADA BURROWS WHEELER COMPRESSION ALGORITHM." Jurnal Terapan Teknologi Informasi 3, no. 1 (July 1, 2019): 21–30. http://dx.doi.org/10.21460/jutei.2019.31.148.

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Kebutuhan kompresi data teks di era komputasi awan saat ini masih cukup tinggi. Data teks perlu dikompresi sekecil mungkin agar mudah dikirimkan. Burrows Wheeler Compression Algorithm (BWCA) adalah salah satu algoritma kompresi teks jenis block sorting yang bersifat non-proprietary dan cukup populer digunakan. Dalam prosesnya, BWCA menggunakan metode pemrosesan awal yang disebut Global Structure Transformation (GST) untuk menyusun karakter agar lebih baik hasil kompresinya. Penelitian ini membandingkan tiga metode pemrosesan awal Move-to-Front, yaitu MTF, MTF-1 dan MTF-2. Bahan uji kompresi berupa data Alkitab Bahasa Inggris, Indonesia dan Jawa, dan beberapa data yang berasal dari Calgary Corpus. Oleh karena kompresi teks adalah kompresi yang bersifat lossless dan reversibel, maka selain melakukan pengujian untuk pengompresian data, juga dilakukan pengujian untuk pendekompresian data dengan Inverse Burrows Wheeler Transform. Pengujian kompresi dan dekompresi pada data Alkitab maupun Calgary Corpus berhasil dilakukan dan menunjukkan MTF-1 mampu memberikan rasio kompresi yang lebih baik dikarenakan jumlah total tiap bit pada proses Huffman lebih sedikit dibandingkan dua metode lainnya.
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Sekyere, Eric O., Louise L. Dunn, Yohan Suryo Rahmanto, and Des R. Richardson. "Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo." Blood 107, no. 7 (April 1, 2006): 2599–601. http://dx.doi.org/10.1182/blood-2005-10-4174.

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AbstractMelanotransferrin (MTf) or tumor antigen p97 is a transferrin homolog that binds one iron (Fe) atom and has been suggested to play roles in a variety of processes, including Fe metabolism, eosinophil differentiation, and plasminogen activation. Considering the vital role of Fe in many metabolic pathways, such as DNA and heme synthesis, it is important to understand the function of MTf. To define this, a MTf knockout (MTf–/–) mouse was generated through targeted disruption of the MTf gene. The MTf–/– mice were viable and fertile and developed normally, with no morphologic or histologic abnormalities. Assessment of Fe indices, tissue Fe levels, hematology, and serum chemistry parameters demonstrated no differences between MTf–/– and wild-type (MTf+/+) mice, suggesting MTf was not essential for Fe metabolism.
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Meligi, Noha M., Amro K. F. Dyab, and Vesselin N. Paunov. "Sustained In Vitro and In Vivo Delivery of Metformin from Plant Pollen-Derived Composite Microcapsules." Pharmaceutics 13, no. 7 (July 9, 2021): 1048. http://dx.doi.org/10.3390/pharmaceutics13071048.

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We developed a dual microencapsulation platform for the type 2 diabetes drug metformin (MTF), which is aimed to increase its bioavailability. We report the use of Lycopodium clavatum sporopollenin (LCS), derived from their natural spores, and raw Phoenix dactylifera L. (date palm) pollens (DPP) for MTF microencapsulation. MTF was loaded into LCS and DPP via a vacuum and a novel method of hydration-induced swelling. The loading capacity (LC) and encapsulation efficiency (EE) percentages for MTF-loaded LCS and MTF-loaded DPP microcapsules were 14.9% ± 0.7, 29.8 ± 0.8, and 15.2% ± 0.7, 30.3 ± 1.0, respectively. The release of MTF from MTF-loaded LCS microcapsules was additionally controlled by re-encapsulating the loaded microcapsules into calcium alginate (ALG) microbeads via ionotropic gelation, where the release of MTF was found to be significantly slower and pH-dependent. The pharmacokinetic parameters, obtained from the in vivo study, revealed that the relative bioavailability of the MTF-loaded LCS-ALG beads was 1.215 times higher compared to pure MTF, following oral administration of a single dose equivalent to 25 mg/kg body weight MTF to streptozotocin (STZ)-induced diabetic male Sprague-Dawley rats. Significant hypoglycemic effect was obtained for STZ-induced diabetic rats orally treated with MTF-loaded LCS-ALG beads compared to control diabetic rats. Over a period of 29 days, the STZ-induced diabetic rats treated with MTF-loaded LCS-ALG beads showed a decrease in the aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides, cholesterol, and low-density lipoprotein-cholesterol (LDL-C) levels, as well as an increase in glutathione peroxidase (GPx) and a recovery in the oxidative stress biomarker, lipid peroxidation (LPx). In addition, histopathological studies of liver, pancreas, kidney, and testes suggested that MTF-loaded LCS-ALG beads improved the degenerative changes in organs of diabetic rats. The LCS-ALG platform for dual encapsulation of MTF achieved sustained MTF delivery and enhancement of bioavailability, as well as the improved biochemical and histopathological characteristics in in vivo studies, opening many other intriguing applications in sustained drug delivery.
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LAROCHELLE, Olivier, Gale STEWART, Pierre MOFFATT, Véronique TREMBLAY, and Carl SÉGUIN. "Characterization of the mouse metal-regulatory-element-binding proteins, metal element protein-1 and metal regulatory transcription factor-1." Biochemical Journal 353, no. 3 (January 25, 2001): 591–601. http://dx.doi.org/10.1042/bj3530591.

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Metal activation of metallothionein gene transcription depends mainly on the presence of regulatory DNA sequences termed metal-regulatory elements (MREs) and involves MRE-binding transcription factor-1 (MTF-1) interacting with the MREs in a Zn2+-dependent manner. We previously identified and characterized a nuclear protein, termed metal element protein-1 (MEP-1), specifically binding with high affinity to MRE elements. The precise relationship between MTF-1 and MEP-1 was unclear, and to determine whether MEP-1 and MTF-1 were distinct protein species, we performed DNA binding analyses to characterize the binding properties of both proteins. Electrophoretic mobility-shift assays showed that MTF-1, produced in COS cells, produces a slower-migrating band compared with that obtained with purified MEP-1. Using an anti-MTF-1 antibody, we showed that both the MTF-1–MRE and the MEP-1–MRE complexes are supershifted by an anti-MTF-1 antibody, thus demonstrating that MEP-1 is antigenically related to MTF-1. RNase protection analyses carried out with RNA prepared from different tissues and cell lines failed to reveal the presence of MTF-1 splicing variants. This indicates that MEP-1 may be a proteolytic fragment of MTF-1. MTF-1 DNA-binding activity was rapidly activated in vivo by Zn2+ ions but not by Cd2+, UV irradiation or PMA, and occurred on ice as well as at 21°C. In control and Zn2+-treated cell extracts, DNA-binding activity was not enhanced in vitro following the addition of exogenous Zn2+ or a preincubation at 37°C. However, recombinant MTF-1 produced in vitro required Zn2+ activation for DNA binding. Interestingly, treatment of nuclear extracts with calf intestine phosphatase completely abrogated MTF-1 DNA-binding activity, thus suggesting that phosphorylation is involved in the regulation of MTF-1 activity.
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Anam, Choirul, Ariij Naufal, Heri Sutanto, and Geoff Dougherty. "Computational phantoms for investigating impact of noise magnitude on modulation transfer function." Indonesian Journal of Electrical Engineering and Computer Science 27, no. 3 (September 1, 2022): 1428. http://dx.doi.org/10.11591/ijeecs.v27.i3.pp1428-1437.

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Accurate measurement of spatial resolution in terms of modulation transfer function (MTF) is essential in computed tomography (CT) images. The purpose of this study was to developed a computational phantom that can be used to evaluate the effect of noise on the MTF in CT images. Our computational phantoms for measuring MTF in CT were developed with MATLAB software. The phantom image was blurred by a point spread function of a certain standard deviation. Subsequently, different noise levels were added to the phantoms. Next, an automatic MTF calculation was implemented. The first step of the MTF calculation was to determine the region of interest (ROI). Profile was generated from the ROI, and a line spread function (LSF) curve was formed. The LSF curve was Fourier transformed to produce a MTF curve. Greater noise added to phantom image, it yields greater effect of standard deviation on the measured MTF. The greater noise makes the MTF curve increases differently than MTF with 0 HU noise. The 10% MTF values at the 25% noise reach more than 2.0 cycle/mm. By the developed computational phantoms, the spatial resolution and the amount of noise can be determined independently.
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Jiang, Jehn-Ruey, and Cheng-Tai Yen. "Product Quality Prediction for Wire Electrical Discharge Machining with Markov Transition Fields and Convolutional Long Short-Term Memory Neural Networks." Applied Sciences 11, no. 13 (June 25, 2021): 5922. http://dx.doi.org/10.3390/app11135922.

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This paper proposes a wire electrical discharge machining (WEDM) product quality prediction method, called MTF-CLSTM, to integrate the Markov transition field (MTF) and the convolutional long short-term memory (CLSTM) neural network. The proposed MTF-CLSTM method can accurately predict WEDM workpiece surface roughness right after manufacturing by collecting and analyzing static machining parameters and dynamic manufacturing conditions. The highly accurate prediction is due to the following two reasons. First, MTF can transform data into images to extract data temporal information and state transition probability information. Second, the CLSTM neural network can extract image spacial features and temporal relationship of data that are separated far apart. In short, MTF-CLSTM predicts WEDM workpiece surface roughness with the MTF model and the CLSTM neural network using static machining parameters and dynamic manufacturing conditions. MTF-CLSTM is compared with 10 related research studies in many aspects. There is only one existing method that is like MTF-CLSTM to predict WEDM workpiece surface roughness by using static machining parameters and dynamic manufacturing conditions. Experiments are conducted to evaluate MTF-CLSTM performance to show that MTF-CLSTM significantly outperforms the existing method in terms of the prediction mean absolute percentage error.
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Yang, G., F. D. Coffman, and E. F. Wheelock. "Characterization and purification of a macrophage-triggering factor produced in Mycoplasma arginini-infected L5178Y cell cultures." Journal of Immunology 153, no. 6 (September 15, 1994): 2579–91. http://dx.doi.org/10.4049/jimmunol.153.6.2579.

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Abstract The supernatant of Mycoplasma arginini-infected murine L5178Y T lymphoma cell cultures (SN-L51) synergizes with small concentrations of IFN-gamma to activate murine peritoneal, thioglycollate-elicited macrophages (M phi) to exhibit cytostatic activity against tumor cells. Treatment of M phi with IFN-gamma and SN-L51 sequentially, but not in the reverse order, activates M phi, which indicates that SN-L51 contains a M phi-triggering factor (MTF). MTF activity could be inhibited by small concentrations of prostaglandin E2, but not by polymyxin B. M phi activated by IFN-gamma plus MTF produce cytostatic effects on tumor cells through a nitric oxide-dependent pathway. MTF activity in SN-L51 is associated with infection of L5178Y cells by M. arginini. Mycoplasma-free L5178Y cells do not produce MTF activity, infection of these L5178Y cells with M. arginini generates the activity, and supernatants of pure M. arginini cultures contain MTF activity. MTF activity is thermostable and resistant to acid, dilute alkali, proteases, and nucleases. MTF was partially purified by ammonium sulfate precipitation, chromatography, electrophoresis, and electroelution. On 12.5% SDS-urea gels, MTF activity migrated with a molecular mass of 2.5 to 4 kDa. MTF activity and the silver staining of this band was resistant to proteinase K; however, Coomassie staining of this band was abolished by proteinase K. The combined data suggest that MTF is either a stable peptide or a peptide linked to lipid or carbohydrate.
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Keum, Woong-Jin, Moo-geon Kim, Ju-Wan Hong, and Yung-Kyoon Kim. "A Study on Spatial Resolution according to Composition Material of ACR phantom in MDCT." Korean Society of Computed Tomographic Technology 24, no. 2 (September 30, 2022): 35–42. http://dx.doi.org/10.31320/jksct.2022.24.2.35.

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The modulation transfer function (MTF) is well known as a crucial parameter in quality assurance of computed tomography (CT) scanners that provides detailed information of both contrast and resolution of CT images. In this study, modulation transfer function (MTF) of multi-detector computed tomography (MDCT) was evaluated by changing the substance of phantom and the measurement parameters. The analysis of MTF gives following results: 1) Bone (the highest contrast material) and air (the lowest contrast material) exhibited variance by 0.030 lp/cm at MTF(50%). 2) In addition, slice thickness of 1.25-mm and 10.0-mm exhibited 0.110 lp/cm and 0.065 lp/cm at MTF(50%), respectively. 3) MTF (50%) showed 50.31% difference depending on the image reconstruction algorithm. Especially, bone algorithm showed higher MTF (50%) than standard algorithm by 26.69%. 4) In addition, the Full (360°) mode linear interpolation showed higher MTF (50%) than the Plus (540°) mode by 10.71%. For a accurate measurement of MTF while performing CT quality control, a phantom module which consists of diverse substance is required. Also, the optimal image which reflecting the size and shape of lesion can be obtained with a suitable scanning factor for diagnosis.
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Porta, Matteo G. Della, Vittorio Rosti, Anna Gallì, Erica Travaglino, Paolo Santambrogio, Carmela Marseglia, Valentina Matti, et al. "The Effects of Mitochondrial Ferritin Expression in Normal and Sideroblastic Erythropoiesis." Blood 114, no. 22 (November 20, 2009): 736. http://dx.doi.org/10.1182/blood.v114.22.736.736.

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Abstract Abstract 736 In erythroid cells from patients with refractory anemia with ringed sideroblasts (RARS), the expression of mitochondrial ferritin (MtF) - encoded by the nuclear FTMT gene located on chromosome 5q21.3 - occurs at a very early stage of differentiation and is closely related to the sideroblastic phenotype [Blood. 2003 Mar 1;101(5):1996-2000]. On the other hand, in extra-hematopoietic tissues MtF expression is associated with high cellular metabolic activity and oxygen consumption, suggesting a possible role of this protein in protecting mitochondria from iron-dependent oxidative damage. It is known that reactive oxygen species (ROS) act as second messengers in the JAK/STAT pathway, which is involved in the regulation of erythropoiesis, and that ROS scavengers inhibit STAT5 phosphorylation. It was the aim of this study to investigate the influence of experimentally induced MtF over-expression on erythroid differentiation in normal hematopoietic progenitors, and in addition to define the relationship between MtF expression and erythroid maturation, apoptosis, and JAK-STAT pathway activation in RARS. A liquid culture model was adopted to expand erythroid progenitors from CD34+ cells in the presence of IL-3, IL-6, stem cell factor and Epo [Blood. 2005 Jul 1;106(1):247-53]. To study the effect of MtF induction in normal hematopoiesis, CD34+ cells from 5 healthy donors were transduced using lentivirus carrying cDNA of FTMT downstream to the ubiquitous PGK promoter (transduction efficiency equal to 30-40%), and then cultured for 21 days. To assess the effect of MtF expression in myelodysplastic syndromes (MDS), CD34+ cells from 24 patients with RARS, as well as cells from 20 patients with refractory anemia (RA) and from 8 healthy donors (as control groups) were cultured. Cytospins were performed for MtF, H-ferritin (HF) and L-ferritin (LF) immunocytochemical analysis, and samples of cultured cells were removed at various days of culture for biological studies. Lentivirus-mediated FTMT transduction of normal CD34+ progenitors did not inhibit cell growth nor prevent the differentiation of erythroid progenitors. By flow cytometry analysis, MtF-positive erythroid progenitors showed significantly reduced levels of HF and increased expression of transferrin receptor (CD71) compared with MtF-negative progenitors (P = .004 and P = .01, respectively). In this model, induction of MtF resulted in increased cellular apoptosis (median number of apoptotic cells by TUNEL assay at day 21 equal to 83% in MtF-positive cells vs 18% in MtF-negative cells, P < .001). A significantly lower proliferation rate and higher apoptotic index were observed in cultures from patients with RARS and RA with respect to healthy controls. FTMT mRNA was detected by RT-PCR in CD34+ progenitor cells from patients with RARS, while protein expression was observed only from day 4 of culture, with a significant increase in the percentage of MtF-positive cells during culture (median value from 5% at day 4 to 24% at day 21, P = .002). No MtF expression was observed in RA patients. In MtF-positive cells from RARS patients, an inverse relationship between MtF and HF cellular content, and a direct relationship between MtF and CD71 expression were observed. In erythroid progenitors from RARS patients, the apoptotic rate was higher in MtF-positive than in MtF-negative cells (median number of apoptotic cells equal to 17% vs 6%, P < .001). Finally, we analyzed by flow cytometry the relationship between MtF expression and STAT5 phosphorylation in cultured cells following Epo stimulation. Preliminary data from three RARS patients showed that p-STAT5 expression was lower in MtF-positive than in MtF-negative cells (P = .02). In conclusion, experimental overexpression of MtF in normal erythroid progenitors may reduce mitochondrial iron availability thus inducing apoptosis. In erythroid progenitors from RARS patients, the pathological expression of MtF is associated with increased apoptosis of immature red cells (ineffective erythropoiesis), which may be at least in part determined by reduced activation of the JAK-STAT pathway in response to Epo. Disclosures: No relevant conflicts of interest to declare.
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Ilias, Ioannis, Manfredi Rizzo, and Lina Zabuliene. "Metformin: Sex/Gender Differences in Its Uses and Effects—Narrative Review." Medicina 58, no. 3 (March 16, 2022): 430. http://dx.doi.org/10.3390/medicina58030430.

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Metformin (MTF) occupies a major and fundamental position in the therapeutic management of type 2 diabetes mellitus (T2DM). Gender differences in some effects and actions of MTF have been reported. Women are usually prescribed lower MTF doses compared to men and report more gastrointestinal side effects. The incidence of cardiovascular events in women on MTF has been found to be lower to that of men on MTF. Despite some promising results with MTF regarding pregnancy rates in women with PCOS, the management of gestational diabetes, cancer prevention or adjunctive cancer treatment and COVID-19, most robust meta-analyses have yet to confirm such beneficial effects.
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Dissertations / Theses on the topic "MTF"

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Sayin, Huseyin. "Tactical Messaging And Usage Of Extensible Markup Language Message Text Formats In The Tactical Command Control And Information Systems." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1224682/index.pdf.

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This thesis investigates the usage area of Extensible Markup Language Message Text Format (XML-MTF) in Tactical Command and Control Information System (TC2IS). It examines the used tactical message types and their application area in Turkish Army and what the XML and XML-MTFs are explained. Finally
MTF traffic of a brigade is simulated to verify that XML technology can be used effectively in Turkish Land Forces Tactical Command Control and Information System Projects (TLF TC2IS).
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Falco, Tony. "MTF, NPS and DQE analysis of portal metal-platefilm detectors." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23885.

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Previous studies of modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE) of metal-plate/film portal detectors have been performed on limited combinations of front and back metal-plates. We report on these parameters for an extensive set of forty-nine front-back metal-plate combinations. The portal detector consists of a double emulsion RP (Kodak localization therapy) film placed between metal-plates: Al, Cu, brass and Pb of thicknesses varying from 0.30 to 4.80 mm. Radiation sources included a Theratron Co-60 unit, and a Varian Clinac-18 linear accelerator delivering a polyenergetic 10 MV X-ray spectrum. In terms of the absolute efficiency of the detectors, the best DQE is obtained with the detector consisting of a 1.75 mm Cu front plate and a 1.62 mm Al back plate for the Clinac-18, and with the detector consisting of a 0.95 mm Cu front plate and a 0.80 mm Cu or a 1.62 mm Al back plate for the Co-60 gamma ray source.
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Macalanda, Eduardo C. "Radio frequency identification (RFID) for Naval Medical Treatment Facilities (MTF)." Thesis, Monterey, California. Naval Postgraduate School, 2006. http://hdl.handle.net/10945/2578.

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The application of Radio Frequency Identification (RFID) technology in hospitals is modest primarily due to cost and policy issues. Similar to the evolution of other electronic technologies, unit costs for components have been dramatically reduced in the past few years. Despite the reduction in costs, RFID technology has not yet achieved the tipping point of economic rationality for adoption at most healthcare organizations. Although the technology has been primarily applied to asset management and supply chain applications, Navy Medicine stands to gain tremendous benefit if this technology could be successfully implemented for staff and patient tracking in addition to inventory management. The purpose of this thesis was to conduct a review of RFID technology and components that could fit into the Navy Medicine's structure. The study explored the implementation requirements associated with the deployment in other industries that could be used as benchmarks for Navy Medicine implementation. Different technological architectures were described to illustrate the various techniques that could be used for creating the opportunity to automate administration, reduce errors and improve security for both patients and staff.
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Silva, Fernanda Amorim Gomes da. "Avaliação temporal e espacial da expressão das metaloproteinases de matriz tipo de membrana (MT2, MT3, MT4, MT5 e MT6-MMP) durante a ossificação endocondral em camundongos." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/23/23141/tde-09112010-105227/.

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As MMPs são endopeptidases zinco dependentes que, em conjunto, podem degradar todos os componentes da MEC e gerar moléculas bioativas. São as principais responsáveis pelo remodelamento tecidual durante eventos fisiológicos normais como a embriogênese e organogênese e também em eventos patológicos como a invasão tumoral nos tecidos. As pesquisas na área de mineralização biológica têm buscado identificar os genes envolvidos nos mecanismos moleculares que regula o processo de ossificação endocondral. As MMPs e seus inibidores são responsáveis pelo controle da degradação desta matriz, como os inibidores teciduais das MMPs (TIMPs) e a proteína RECK, que, muito provavelmente, determinam o grau de remodelação da matriz extracelular. Desta forma, nosso objetivo foi delinear o perfil temporal e espacial da expressão das MMP-15/MT2-MMP, MMP-16/MT3- MMP, MMP-17/MT4-MMP, MMP-24/MT5-MMP e MMP-25/MT6-MMP durante a ossificação endocondral em embriões de camundongos e em animais recémnascidos através das técnicas de PCR em tempo real e imunohistoquímica. Por imunohistoquímica, nós não encontramos imunomarcação para a MMP-15/MT2- MMP em nenhum dos períodos analisados, apesar da padronização do anticorpo primário. Tanto a MMP-16/MT3-MMP quanto a MMP-24/MT5-MMP foram imunolocalizadas, principalmente, nos osteoblastos do fronte de ossificação da placa de crescimento. Para a MMP-17/MT4-MMP, durante a diferenciação condrocítica (E13) os condrócitos proliferativos foram imunocorados, bem como os condrócitos hipertróficos no centro da cartilagem do molde cartilaginoso (E14). Durante a invasão celular e vascular (E15), as células mesenquimais oriundas do colar ósseo, provavelmente pré-osteoblastos, foram imunocorados na cavidade medular primitiva e osteoblastos fronte de ossificação foram imunocorados, de E16 a PN1. Observamos para a MMP-25/MT6-MMP o mesmo padrão de imunomarcação das demais MT-MMPs, exceto no molde cartilaginoso, onde apenas as células do periósteo e pericôndrio foram imunocoradas, diferentemente da demais que foram localizadas apenas no centro do molde cartilaginoso. A análise da expressão dos transcritos para todas as MT-MMPs revelou o mesmo perfil de expressão, sendo alta durante a fase de diferenciação condrocítica (E13), tendo queda de expressão de E14 a E16. Em E16 há um aumento de expressão até E18 e, novamente, queda até E20 e pouca ou nenhuma expressão em PN7. Apesar deste perfil semelhante, houve uma expressão diferencial entre elas, sendo a MMP-15/MT2-MMP > MMP- 17/MT4-MMP > MMP-16/MT3-MMP > MMP-24/MT5-MMP > MMP-25/MT6/MMP. Os resultados obtidos mostram, pela primeira vez, que as MT-MMPs estão diferencialmente expressas durante a ossificação endocondral normal em camundongos, sugerindo que a atividade biológica destas enzimas esteja atuando na degradação da matriz extracelular pericelular tanto durante a fase de desenvolvimento quanto de formação óssea.
MMPs are zinc-dependent endopeptidases that, collectivelly, degrade all components of the ECM and generate bioactive molecules. They are able to remodelate the ECM during normal developmental processes such as embryogenesis and organogenesis, as well as in pathological processes such as tumoral invasion. The biological mineralization research looking for discovering the genes involved in the molecular mechanisms that control the endochondral ossification process. MMPs and their inhibitors (TIMPs and RECK) are responsable for bone matrix remodeling and, probably, determinate the level of its turnover. Thus, our goal was to evaluate the temporal-spatial expression of MMP-15/MT2-MMP, MMP-16/MT3-MMP, MMP-17/MT4-MMP, MMP-24/MT5-MMP, and MMP-25/MT6- MMP in mice embryos and newborns during endochondral ossification by Real Time PCR and immunohistochemistry. By immunohistochemistry, MMP-15/MT2-MMP signal was not detected. Both MMP-16/MT3-MMP and MMP-24/MT5-MMP were immunostained, mainly in osteoblasts at ossification front of growth plate. For MMP- 17/MT4-MMP, proliferative chondrocytes were immunopositive during chondrocyte differentiation (E13) as well as in hipertrophyc chondrocytes at the middle of cartilaginous template (E14). During cellular e vascular invasion (E15), mesenchymal cells from bone collar, probable pre-osteoblasts, were immunostained at primary bone marrow and osteoblasts at ossification front from E16 e PN1. For MMP- 25/MT6-MMP, perichondrial and periostal cellls were immunostained at cartilaginous template. All MT-MMPs evaluated showed the same transcript levels profile, being high in chondrocyte differentiation (E13), decreasing from E14 to E16. mRNA levels increased from E16 to E18 and, once more, decreasing from E18 to E20. Despite this profile, we observed difference levels: MMP-15/MT2-MMP > MMP-17/MT4-MMP > MMP-16/MT3-MMP > MMP-24/MT5-MMP > MMP-25/MT6/MMP. Our findings show, for the first time, that MT-MMPs are differentially expressed during normal endochondral ossification in mice, suggesting their biological activity act in pericellular extracellular matrix degradation in both development and bone formation.
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Scaduto, Lucimara Cristina Nakata. "Desenvolvimento e avaliação do desempenho de sistema óptico aplicado a sensoriamento remoto orbital." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-02032009-135211/.

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Este trabalho tem como objetivo apresentar o sistema óptico desenvolvido para a câmera WFI (Wide Field Imaging Camera) que integrará os satélites CBERS 3 e 4 (China Brazil Earth Resources Satellite). O Brasil é responsável por duas das câmeras dos satélites CBERS 3 e 4, a WFI e a MUX (Multispectral Camera). Estas câmeras são destinadas a sensoriamento remoto orbital da Terra. É a primeira vez que câmeras destinadas a este tipo de aplicação são inteiramente desenvolvidas e construídas no país. Devido ao alto nível de vibração durante o vôo, à exposição a vácuo e a radiação espacial durante o período de vida útil em órbita, o desenvolvimento desta câmera exige um cuidadoso processo de análise e avaliação do desempenho óptico em terra de modo a garantir seu funcionamento a bordo. Em especial, serão apresentados as análises ópticas realizadas durante a fase de projeto preliminar e os testes ópticos realizados em terra dos requisitos: distância focal, campo de visada - FOV, função de transferência de modulação - MTF, distorção, sensibilidade à polarização, transmitância, sensibilidade à luz espalhada e degradação da transmitância com a radiação espacial. Os resultados obtidos comprovaram que o desempenho do sistema óptico atende os requisitos de projeto.
The purpose of this work is to present the optical system developed for the WFI camera (Wide Field Imaging Camera), which will be integrated to the CBERS 3 and 4 satellites (China Brazil Earth Resources Satellite). Brazil is responsible for two cameras of CBERS 3 and 4 satellites, WFI and MUX (Multispectral Camera). These cameras are used for orbital remote sensing of the Earth. It is the first time that cameras for this type of application are being entirely developed and built in our country. Due to the high vibration level during flight, the vacuum and space radiation exposure during the lifetime in orbit, the development of this camera requires a meticulous analysis process and evaluation of optical performance on the ground in order to ensure the effective operation on board. In particular, the optical analyses performed during the preliminary design and optical test requirements performed on ground will be presented, such as: focal length, field of view - FOV, modulation transfer function - MTF, distortion, polarization sensitivity, transmittance, stray light sensitivity and transmittance degradation with space radiation. The results obtained exhibit that the optical system performance satisfies all project requirements.
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Bradley, Karen Nicola. "The in vitro effects of muscarinic toxins MT2, MT3, MT4 and MT7 isolated from the venom of Dendroaspis angusticeps." Thesis, University of Strathclyde, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366919.

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Waxin, Viktor, and Oliver Forslund. "Succé eller fiasko? : - Hur påverkas bolagsavkastning av byte mellan Sveriges MTF-marknadsplatser." Thesis, Mittuniversitetet, Avdelningen för ekonomivetenskap och juridik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-30966.

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Det finns ett flertal tidigare studier som undersöker listbyten och dess effekt på ett bolags aktieavkastning. Merparten av dessa studier är dock baserade på den amerikanska aktiemarknaden. De svenska studierna som har genomförts undersöker effekten av listbyte från alternativa marknadsplatser (MTF) till huvudmarknaden (reglerad marknad). Det har framkommit att det finns ett kunskapsgap vad gäller hur aktieavkastning reagerar på marknadsplatsbyten på Sveriges MTF-er. Genom att endast fokusera på MTFmarknadsplatserna,AktieTorget, First North och Nordic MTF i Sverige och effekten av bytenmellan dessa marknadsplatser blir denna studie ett komplement till den tidigare forskningen inom området. I studien undersöks 39 svenska bolag som mellan åren 2007-2016 valt att byta marknadsplats. OMXPI är det jämförelseindex som använts för att jämföra bolagens avkastning med marknaden. Syftet med denna studie är att undersöka om det finns ett värdeför såväl bolagen som dess aktieägare att byta marknadsplats mellan AktieTorget, Nordic MTF och First North, istället för att stanna kvar på den ursprungliga listan. Detta syfte uppnås genom att studien undersöker bolagens aktieavkastning i samband med flytt till likvärdig, alternativ, marknadsplats för att ta reda på om bytet av marknadsplats skapar en negativ avkastning hos bolagen. Denna studie utförs i form av en kvantitativ eventstudie där marknadsplatsbytet utgör eventet. Studiens avsikt är inte att analysera de enskilda bolagen utan att istället ge en samlad bild av effekten på den aktiekursutveckling listbytet medför. Resultatet av studien visar att en negativ ackumulerad onormal avkastning (CAR) förekommer efter att marknadsplatsbytet genomförts. Vid beräkning av parametrarna imarknadsmodellen finner studien att den genomsnittliga ackumulerade onormala avkastningen (CAAR) för samtliga bolag är hela -47,88 %, 12 månader efter att marknadsplatsbytet genomförts.
There are several previous studies that examine switches between marketplaces and how these changes impact companies share performance. The most foregoing research made on the subject share performance is based on the US stock market. Swedish studies made to the subject examine the share performance when companies move from one of the SwedishMultilateral Trading Facilities (MTF) to main market. The authors of this paper have noted that there is a gap of knowledge regarding share performance when companies move between the Multilateral Trading Facilities. By only examining the Swedish Multilateral Trading Facilities, AktieTorget, First North and Nordic MTF, and how moving between the lists affects the share performance, this study is an addition to the previous research in the field.This study examines 39 Swedish companies, which have changed list between 2007-2016. OMXSPI is the benchmark used in this study to compare the companies return with the market return. The purpose of this study is to examine if there is a value for both the companies and its shareholders to exchange marketplaces between the Swedish Multilateral Trading Facilities, AktieTorget, First North and Nordic MTF. This purpose is achieved byexamine the company’s stock price development before and after the change of market place and identify if the change creates a negative share performance. This study is conducted in the form of a quantitative event study where the marketplace change represents the event. The purpose is not to analyze the individual companies but to provide a comprehensive picture ofthe effect the marketplace changes have on the stock price development. The result of the study indicates that a negative accumulated abnormal return (CAR) occurs after the marketplace change. When calculating the parameters in the market model the study finds that the average accumulated abnormal return (CAAR) for all companies is a total of -47,88 % twelve months after the marketplace change.
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Dubé, Annie. "Étude des mécanismes impliqués dans l'activation de MTF-1 en réponse à l'hypoxie." Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26379/26379.pdf.

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Millstone, Daniel Brucker, and Daniel Brucker Millstone. "Edge Response Characterization of Interferometers and the Effect of Aberrations." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/625697.

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An edge response characterization technique to predict the ITF of an interferometer using non- interferometric measurements has been shown to be effective. This technique eliminates the need for phase objects to be used in the characterization process. Using coherent imaging with an irradiance sensitive detector and an irradiance step as a characterization artifact to determine an interferometer's ITF was proven viable for diffraction limited, defocused, astigmatic, and spherically aberrated systems. Simulations and collected data demonstrated agreement between the interferometric edge response characterization technique results and coherent imaging edge response characterization technique results. The effect that aberrations have on ITF curves has been investigated in this thesis and an understanding of the system behavior under aberrated conditions was investigated.
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Santos, Caio Augusto Marques dos [UNESP]. "Cronogeomorfologia do relevo da cidade de Marília através do método de traços de fissão - MTF." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/108680.

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Made available in DSpace on 2014-08-13T14:50:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-04-23Bitstream added on 2014-08-13T18:00:15Z : No. of bitstreams: 1 000763321.pdf: 2204841 bytes, checksum: 7b83ab82bb6ed5922a3afb883d4c0d2a (MD5)
O Planalto Residual de Marília é uma morfoescultura localizada no Planalto Ocidental Paulista e na morfoestrutura da Bacia Sedimentar do Paraná. Ele possui como substrato rochoso os arenitos da Formação Marília (Grupo Bauru – Cretáceo Superior). Com o objetivo de verificar o papel e a importância da tectônica para sua gênese e evolução, realizou-se a datação de 110 grãos de zircão e 59 de apatita via Método Traços de Fissão-MTF. Ele se baseia em análises termocronológicas, fundamentado no estudo quantitativo de perturbações no retículo cristalino desses minerais provocados pela fissão espontânea do núcleo do isótopo 238U, que ocorre durante o tempo geológico. Os resultados obtidos em zircão tiveram intervalo de idade que variou de 640 até 70 Ma. Nas apatitas a variação foi de 489 a 71 Ma. Esses intervalos grandes de idades foram atribuídos a várias procedências de rochas-fontes de sedimentos para o substrato rochoso do planalto. Ao analisar os espectros de idades dos dois minerais, agrupou-os em três conjuntos, aos quais se associaram eventos termotectônicos: idades superiores a 470 Ma - colisões brasilianas...
The Marília Residual Plateau is a morfosculpture located in Paulista Western Plateau and in morfostructure of the Paraná Sedimentary Basin. It has as rock substratum the sandstones of Marília Formation (Bauru Group - Late Cretaceous). In order to check the role and importance of tectonics to its genesis and evolution, it was done the dating of 110 grains of zircon and 59 of apatite by Fission Track Method - MTF. This method is based on thermal-chronological analyzes, grounded on the quantitative study of disturbances at the crystal lattice of these minerals caused by the spontaneous fission of the nucleus of 238U isotope, which occurs along geological time. The results obtained for zircon had ages break between 640 to 70 Ma. In apatite the variation was from 489 to 71 Ma. These large ranges of age were attributed to several origins of source rocks that provide the sediments to rock substratum of plateau. By analyzing the age spectrum of these two minerals, they were grouped into three sets, associated with thermo-tectonic events: ages over 470 Ma - brasiliano...
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Books on the topic "MTF"

1

Benjamin, Walton, ed. SBA and MTF MCQs for the primary FRCA. Cambridge: Cambridge University Press, 2012.

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Verma, R. Design and commissioning of 1.2 MJ capacitor bank "rudra" for MTF & plasma focus experiments. Mumbai: Bhabha Atomic Research Centre, 2010.

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Sanderink, Gerard Clement Herman. Imaging characteristics in rotational panoramic radiography: Practical testing and mathematical models using MTF and ROC analysis. Utrecht: University of Utrecht, Department of Oral Roentgenology, 1987.

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Murray, Mark W. Automatically generating a distributed 3D virtual Battlespace using USMTF and XML-MTF air tasking orders, Extensible Markup Language (XML) and Virtual Reality Modeling Language (VRML). Monterey, Calif: Naval Postgraduate School, 2000.

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Minskiĭ, mezhdunarodnyĭ forum po teplomassoobmenu (2nd 1992 Minsk Belarus). Teplomassoobmen--MMF-92: II Minskiĭ mezhdunarodnyĭ forum, 18-22 mai͡a︡ 1992 = Heat/mass transfer--MIF-92. Minsk: Akademii͡a︡ nauk Belarusi, ANK "In-t teplo- i massobmena im. A.V. Lykova", 1992.

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Minskiĭ mezhdunarodnyĭ forum po teplomassoobmenu (3rd 1996 Minsk, Belarus). Teplomassoobmen--MMF-96: III Minskiĭ mezhdunarodnyĭ forum, 20-24 mai͡a︡ 1996 g. = Heat/mass transfer--MIF-96. Minsk: Akademii͡a︡ nauk Belarusi, ANK "In-t teplo- i massoobmena im. A.V. Lykova", 1996.

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Mif Versache. Sankt-Peterburg: Azbuka-klassika, 2008.

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Mykolajovyč), Dovhopolyj Jaroslav (Jaroslav, ed. Mif Odesy. Kyïv: Dukh i litera, 2011.

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Institut filosofii (Rossiĭskai︠a︡ akademii︠a︡ nauk), ed. Mif tekhniki. Moskva: Nauka, 2004.

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Rzhekhina, Olʹga Ivanovna. M.F. Olenev. Gorki: Prosperus, 1996.

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Book chapters on the topic "MTF"

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Patel, Nisha R., Michael L. Wong, Anthony E. Dragun, Stephan Mose, Bernadine R. Donahue, Jay S. Cooper, Filip T. Troicki, et al. "Modulation Transfer Function (MTF)." In Encyclopedia of Radiation Oncology, 503. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-540-85516-3_426.

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Glass, Allison S., and Marci L. Bowers. "Complications of MTF Vaginoplasty." In Management of Gender Dysphoria, 153–60. Milano: Springer Milan, 2015. http://dx.doi.org/10.1007/978-88-470-5696-1_17.

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Nameda, Naoyoshi, Masato Masuya, Yuji Shimizu, and Eiichi Hatae. "Easy Human Visual MTF Measurements." In Optics and Lasers in Biomedicine and Culture, 260–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-56965-4_49.

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Trombetta, Carlo. "MtF Sex Reassignment Surgery: Trombetta Technique." In Practical Clinical Andrology, 291–305. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-11701-5_23.

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AbstractGender affirming surgery should provide satisfying results in terms of aesthetic and functional outcomes, therefore, no standard procedure could fit for every subject. Penoscrotal flap technique with neoclitoral-neourethral complex confreres acceptable outcomes, is reproducible in different anatomical scenarios and not involves major abdominal surgery.
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Stump, David. "MTF, Resolution, Contrast, and Nyquist Theory." In Digital Cinematography, 103–19. 2nd ed. New York: Routledge, 2021. http://dx.doi.org/10.4324/9780429468858-5.

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Voigt, Herbert, and Ratko Magjarević. "Svensk förening för medicinsk teknik och fysik (MTF)." In Launching IFMBE into the 21st Century: 50 Years and Counting, 242–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-30160-5_111.

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Michoud, Bruno, and Manfred Hafner. "Annex." In Financing Clean Energy Access in Sub-Saharan Africa, 153–97. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75829-5_12.

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AbstractThis annex includes the following tables discussed in previous chapters of the book: (i) definition of the Tiers of the Multi-Tier Framework (MTF) initiative; (ii) population with access to electricity and clean cooking in African countries; (iii) risks associated with investment opportunities and stakeholders; (iv) the de-risking matrix; (v) carbon tax and emission trading systems; (vi) MSCI market classification framework and requirements.
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Andrews, Glen K. "Cellular zinc sensors: MTF-1 regulation of gene expression." In Zinc Biochemistry, Physiology, and Homeostasis, 37–51. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-017-3728-9_3.

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Andersen, Michael I., and Anton Norup Sørensen. "An Interferometric Method for Measurement of the Detector MTF." In Optical Detectors for Astronomy, 187–90. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5262-4_28.

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Liu, Peng, Dingsheng Liu, and Fang Huang. "MTF Measurement Based on Interactive Live-Wire Edge Extraction." In Computational Science – ICCS 2007, 523–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-72586-2_77.

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Conference papers on the topic "MTF"

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Dror, Itai, and Norman S. Kopeika. "Comparison of turbulence MTF and aerosol MTF." In Aerospace Sensing, edited by Anton Kohnle and Walter B. Miller. SPIE, 1992. http://dx.doi.org/10.1117/12.137938.

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Dror, Itai, and Norman S. Kopeika. "Overall atmospheric MTF and aerosol MTF cutoff." In Orlando '91, Orlando, FL, edited by Luc R. Bissonnette and Walter B. Miller. SPIE, 1991. http://dx.doi.org/10.1117/12.46573.

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Katz, Milton, Karl Citek, and Aries Arditi. "Modulation transfer function system for testing telescopic and telemicroscopic low-vision aids." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1985. http://dx.doi.org/10.1364/oam.1985.fi1.

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As part of a study of the relationship between the optical quality of low-vision aids and the quality of vision provided by these devices we wanted to measure their modulation transfer functions (MTF). We present our apparatus for measuring the MTF of low-power telescopes and telemicroscopes (instruments that are nominally afocal in image space). We can test at spatial frequencies up to 100 cycles/deg in object space. MTF tests may be made across the field of vision, through focus, at 0°, 45°, 90°, and 135° scan azimuths, with white light or passband filters, and with artificial pupils. A computerized data acquisition and analysis system corrects digital data for noise, and computes and plots the MTF curves. MTFs of some commonly prescribed telescopic aids are shown and compared.
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Bardoux, Alain, Thierry Gimenez, Nicolas Jamin, and Frederic Seve. "Dynamic MTF measurement." In International Conference on Space Optics 2010, edited by Naoto Kadowaki. SPIE, 2017. http://dx.doi.org/10.1117/12.2309157.

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Kopeika, Norman S., Arkadi Zilberman, and Yitzhak Yitzhaky. "Aerosol MTF revisited." In SPIE Defense + Security, edited by Gerald C. Holst, Keith A. Krapels, Gary H. Ballard, James A. Buford, and R. Lee Murrer. SPIE, 2014. http://dx.doi.org/10.1117/12.2052912.

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White, Benjamin S., and Michael J. Marquis. "Vertical MTF measurements." In Optical Engineering and Photonics in Aerospace Sensing, edited by Gerald C. Holst. SPIE, 1993. http://dx.doi.org/10.1117/12.154712.

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Carellas, Peter, and Stephen Wilk. "How to measure MTF." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1993. http://dx.doi.org/10.1364/oam.1993.tucc.1.

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Modulation transfer function (MTF) is quickly becoming a popular method of determining the quality of optical systems. We discuss various methods currently used to measure MTF, from traditional target projections to new video-based real-time systems. A sampling of actual and theoretical MTF test results are discussed for general and specific applications.
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Freedman, Ellis, and Robert Fleming. "The Constant MTF Interpolator a resampling technique with minimal MTF losses." In 2016 IEEE Signal Processing in Medicine and Biology Symposium (SPMB). IEEE, 2016. http://dx.doi.org/10.1109/spmb.2016.7846878.

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Rimmer, Matthew P., Thomas J. Bruegge, and Thomas G. Kuper. "MTF Optimization in Lens Design." In International Lens Design. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/ild.1990.lmc4.

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Optimization programs generally use a merit function which is related to mean square spot size or wave aberration. Direct MTF optimization has been tried, but with limited success. One problem, which makes it almost unusable in the early stages of the design, is the fact that MTF values are bounded between 0.0 and 1.0 and oscillate significantly as a function of the constructional parameters. Another is the long calculation time needed for MTF. Approximations to the MTF have generally been used. Wavefront variance and wavefront difference variance are two of the more common ones that avoid both problems but don't directly optimize MTF. The variance is closely related to MTF for systems near the diffraction limit but poorly related for RMS wavefront errors greater than about 0.2 waves. The wavefront difference variance is, likewise, applicable only over a restricted region.1
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Shea, James J. "On-orbit MTF measurements." In SPIE's 1996 International Symposium on Optical Science, Engineering, and Instrumentation, edited by Edward R. Washwell. SPIE, 1996. http://dx.doi.org/10.1117/12.254070.

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Reports on the topic "MTF"

1

Kallman, Jeffrey S. Method to Compute CT System MTF. Office of Scientific and Technical Information (OSTI), May 2016. http://dx.doi.org/10.2172/1256443.

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Whitlock, Warren L. MTF Computerized Decision Support for Chemical Hazard Emergencies. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada421090.

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Estep, Lee, and R. Arnone. Impact on the Medium MTF by Model Estimation of b. Fort Belvoir, VA: Defense Technical Information Center, January 1991. http://dx.doi.org/10.21236/ada247985.

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Smith, Roger J. Internal field, density & temperature measurements in MTF plasmas using Pulsed Polarimetry. Office of Scientific and Technical Information (OSTI), August 2014. http://dx.doi.org/10.2172/1149491.

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McBride, Walton. MTF-Derived Image Metric for the Performance of Laser-Based Imaging Systems. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada533635.

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McBride, Walton. MTF-Derived Image Metric for the Performance of Laser-Based Imaging Systems. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada627963.

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McBride, III, and Walton E. MTF-Derived Image Metric for the Performance of Laser-Based Imaging Systems. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada633764.

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Kiuttu, Gerald F., Sean Coffey, Frank Camacho, Al Lerma, Mark Kostora, and Wayne Sommars. High Energy Research and Applications (HERA) Pulsed Power and Pulsed Power Systems R&D for Magnetized Target Fusion Using Field Reversed Configurations (MTF-FRC). Fort Belvoir, VA: Defense Technical Information Center, March 2013. http://dx.doi.org/10.21236/ada589215.

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Georgiev, Georgi N., Milena Mourdjeva, Tsvetelina Oreshkova, Roumen Pankov, and Rossitza Konakchieva. MT1 and MT2 Melatonin Receptor Expression and In Vitro Melatonin Effect on the PHA‑dependent Activation of Human PBMC. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, December 2019. http://dx.doi.org/10.7546/crabs.2019.11.07.

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Margolis, D., M. Risher, B. Ramakrishnan, A. Brotman, and J. Jones. SMTP MTA Strict Transport Security (MTA-STS). RFC Editor, September 2018. http://dx.doi.org/10.17487/rfc8461.

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