Academic literature on the topic 'MUA'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'MUA.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "MUA"
1
Rivas, Ramón D. "Museo Universitario de Antropología, MUA." Revista de Museología "Kóot", no. 3 (July 14, 2013): 117–20. http://dx.doi.org/10.5377/koot.v0i3.1168.
Full text
2
Shaka, Angeline. "Hula for the Future: Patrick Makuakāne and the Hula Mua “Salva Mea”." Theatre Journal 67, no. 3 (2015): 487–501. http://dx.doi.org/10.1353/tj.2015.0086.
Full text
3
Knapp, Paul, Luke Weishuhn, Natalie Pizzimenti, and David C. Markel. "Risk factors for manipulation under anaesthesia after total knee arthroplasty." Bone & Joint Journal 102-B, no. 6_Supple_A (June 2020): 66–72. http://dx.doi.org/10.1302/0301-620x.102b6.bjj-2019-1580.r1.
Full textAbstract:
Aims Postoperative range of movement (ROM) is an important measure of successful and satisfying total knee arthroplasty (TKA). Reduced postoperative ROM may be evident in up to 20% of all TKAs and negatively affects satisfaction. To improve ROM, manipulation under anaesthesia (MUA) may be performed. Historically, a limited ROM preoperatively was used as the key harbinger of the postoperative ROM. However, comorbidities may also be useful in predicting postoperative stiffness. The goal was to assess preoperative comorbidities in patients undergoing TKA relative to incidence of postoperative MUA. The hope is to forecast those who may be at increased risk and determine if MUA is an effective form of treatment. Methods Prospectively collected data of TKAs performed at our institution’s two hospitals from August 2014 to August 2018 were evaluated for incidence of MUA. Comorbid conditions, risk factors, implant component design and fixation method (cemented vs cementless), and discharge disposition were analyzed. Overall, 3,556 TKAs met the inclusion criteria. Of those, 164 underwent MUA. Results Patients with increased age and body mass index (BMI) had decreased likelihood of MUA. For every one-year increase in age, the likelihood of MUA decreased by 4%. Similarly, for every one-unit increase in BMI the likelihood of MUA decreased by 6%. There were no differences in incidence of MUA between component type/design or fixation method. Current or former smokers were more likely to have no MUA. Surprisingly, patients discharged to home health service or skilled nursing facility were approximately 40% and 70% less likely than those discharged home with outpatient therapy to be in the MUA group. MUA was effective, with a mean increased ROM of 32.81° (SD 19.85°; -15° to 90°). Conclusion Younger, thinner patients had highest incidence of MUA. Effect of discharge disposition on rate of MUA was an important finding and may influence surgeons’ decisions. Interestingly, use of cement and component design (constraint) did not impact incidence of MUA. Level of Evidence II: Prospective cohort study. Cite this article: Bone Joint J 2020;102-B(6 Supple A):66–72.
4
Pierce, Todd, Kimona Issa, Anthony Festa, Anthony Scillia, Vincent McInerney, and Michael Mont. "Does Manipulation under Anesthesia Increase the Risk of Revision Total Knee Arthroplasty? A Matched Case Control Study." Journal of Knee Surgery 30, no. 07 (February 14, 2017): 730–33. http://dx.doi.org/10.1055/s-0037-1598040.
Full textAbstract:
Manipulation under anesthesia (MUA) can help patients regain an adequate range of motion (ROM) following total knee arthroplasty (TKA). Although there are studies reporting that MUA can assist in improving ROM, there is a paucity of studies regarding whether requiring an MUA is associated with an increased risk of revision. The purpose of this study was to assess the: (1) incidence of revision TKA and (2) outcomes of those undergoing MUA and compare it with a matched cohort who did not require MUA. A prospectively collected database of two high-volume institutions was assessed for patients who required a single MUA following TKA between 2005 and 2011. We found a total of 138 knees with a mean 8.5-year follow-up post-MUA. We compared this with a matched cohort (1:1) who underwent TKA during this same time period but did not require an MUA. Incidence of revision surgery and clinical outcomes were compared between the two cohorts. Within the MUA cohort, nine knees underwent revision, which was similar to the matched cohort that had seven revisions (93 vs. 95%; p = 0.6). The mean KSS-functional (88 vs. 90 points; p = 0.15) and clinical scores (87 vs. 89 points; p = 0.1) were similar between the two cohorts. Undergoing an MUA was not associated with an increased risk of revision TKA. If patients require MUA, they may still achieve satisfactory outcomes. This information can be used in educating patients so they may be able to formulate their expectations following their MUA.
5
Chirea, Mariana, Carlos M. Pereira, and Fernando Silva. "Hydrogen Bonding: A Bottom-Up Approach for the Synthesis of Films Composed of Gold Nanoparticles." Journal of Nano Research 2 (August 2008): 115–28. http://dx.doi.org/10.4028/www.scientific.net/jnanor.2.115.
Full textAbstract:
Citrate gold nanoparticles of 13.5 nm average diameters have been synthesized by Turkevich method and further functionalized by place exchange reaction using mercaptosuccinic acid (MSA), 1,4-benezenedimethanethiol (1,4BDMT) or mercaptoundecanoic acid (MUA) as the incoming ligands. In the first case, the functionalization of the gold clusters with MSA yielded solution of blue color and large aggregates on carbon grids. Moreover, after filtration and drying, any film formed by hydrogen bonding, could not be removed from the filter, being embedded into the filter texture. The second ligand used for the place exchange reaction, the 1,4BDMT, determined the change of the solution color from red to dark purple, and generation of a purple powder but no film formation. In the third case, the purification and drying of the MUA functionalized gold clusters yielded films of purple color with homogenous composition, robustness, soft topographies and remarkable optical properties which were dependent on their thicknesses. The Au-MUA NP films obtained are new, being generated by hydrogen bonding and having features which makes them very attractive for the fabrication of optoelectronic devices. The long alkyl chained thiol proved to be the adequate ligand for film synthesis.
6
Minh, Nguyễn Thị Bình, Khúc Đình Nam, and Trần Thị Thanh Thuận. "Các nhân tố ảnh hưởng đến quyết định mua bảo hiểm nhân thọ của khách hàng cá nhân tại Tp. Hồ Chí Minh." TẠP CHÍ KHOA HỌC ĐẠI HỌC MỞ THÀNH PHỐ HỒ CHÍ MINH - KINH TẾ VÀ QUẢN TRỊ KINH DOANH 16, no. 2 (May 29, 2021): 156–69. http://dx.doi.org/10.46223/hcmcoujs.econ.vi.16.2.961.2021.
Full textAbstract:
Mục tiêu nghiên cứu này là xác định các nhân tố ảnh hưởng đến quyết định mua Bảo Hiểm Nhân Thọ (BHNT) của khách hàng cá nhân tại TP. Hồ Chí Minh. Nhóm tác giả đã thu thập dữ liệu thông qua phỏng vấn 251 khách hàng cá nhân đã mua BHNT tại địa bàn nghiên cứu. Mô hình nghiên cứu được xây dựng dựa trên sự kết hợp giữa lý thuyết về quá trình ra quyết định (Kotler & Keller, 2012) và lý thuyết về hành vi người tiêu dùng (Sheth, Mittal, & Newman, 1999). Kết quả nghiên cứu cho thấy có 05 nhân tố ảnh hưởng đến quyết định mua mua bảo hiểm nhân thọ được sắp xếp theo thứ tự mức độ giảm dần như sau: (i) Nhận thức về giá trị của BHNT, (ii) Thương hiệu công ty BHNT, (iii) Rào cản mua BHNT, (iv) Tư vấn viên BHNT và (v) Động cơ mua BHNT; trong đó chỉ có nhân tố Rào cản mua BHNT có tác động nghịch chiều với quyết định mua BHNT còn các nhân tố khác có tác động cùng chiều với quyết định mua. Sau cùng, nhóm tác giả đề xuất một số khuyến nghị nhằm gia tăng khách hàng cá nhân tham gia BHNT và hướng nghiên cứu trong tương lai.
7
Mohammed, Riazuddin, Shakir Syed, and Naveed Ahmed. "Manipulation Under Anaesthesia for Stiffness Following Knee Arthroplasty." Annals of The Royal College of Surgeons of England 91, no. 3 (April 2009): 220–23. http://dx.doi.org/10.1308/003588409x359321.
Full textAbstract:
INTRODUCTION Stiffness following knee arthroplasty is a frustrating complication and a significantly disabling problem. We present our experience of knee stiffness requiring manipulation under anaesthesia (MUA) as the first line of treatment following partial or total knee arthroplasty. PATIENTS AND METHODS All stiff knees requiring MUA over a 6-month period from March to August 2007 were retrospectively analysed from theatre records and case notes. Data were collected regarding demographics, range of knee motion before and after manipulation and at subsequent follow-up. Complications of the procedure and outcomes were also analysed. RESULTS Twenty-one patients (11 female, 10 male) underwent MUA. The average age was 62 years (range, 56–80 years). Sixteen primary and 3 revision total knee replacements underwent manipulation, as did one medial unicompartmental replacement and one patellofemoral arthroplasty. General anaesthesia with good muscle relaxation was used in all but one patient. The mean duration between arthroplasty and MUA was 13.2 weeks (range, 6-32 weeks). The range of knee movement improved from a mean range of 10.4–71.2° in the pre-MUA period to 2.1–94.0° post-MUA and at follow-up was 2.3–91.9°. The mean arc of motion improved from 60.2° (range, 40–80°) pre-MUA to 91.9° (range, 45–120°) post-MUA. The mean improvement in the arc of motion was 31.6° (P < 0.001). At an average follow-up of 3 months (range, 6 weeks to 8 months), the mean arc of motion was 90.4° (range, 40–120°). The mean improvement in knee movement from the pre-MUA at the follow-up was 30.2° (P < 0.001). One patient failed to gain any improvement from MUA. There were no complications noted from the procedure. CONCLUSIONS MUA has a role in the treatment of early stiffness with excellent immediate outcomes. We advocate that MUA should be the first line of management for stiff knee arthroplasties after failed physiotherapy.
8
Nguyên, Ðình-Hoà, and Nguyên Thi Ngọc-Dung. "Sài gòn Năng Nhó Mua Thuong." World Literature Today 71, no. 4 (1997): 879. http://dx.doi.org/10.2307/40153511.
Full text
9
Somfongbouthtakhan, Chinda. "THE IMPACTS OF DIGITAL MARKETING ON ONLINE SHOPPING BEHAVIOR THROUGH ONLINE SHOPPING APPLICATION IN THAI NGUYEN CITY." TNU Journal of Science and Technology 226, no. 09 (June 4, 2021): 65–72. http://dx.doi.org/10.34238/tnu-jst.4379.
Full textAbstract:
Bài nghiên cứu này chỉ ra tác động của tiếp thị số lên hành vi mua sắm online thông qua các ứng dụng mua hàng online, tập trung vào ngành công nghiệp bán lẻ ở Thái Nguyên. Đặc biệt, bài viết cũng sẽ đưa ra vai trò trung gian của các ứng dụng mua sắm online trong mối quan hệ giữa tiếp thị số và hành vi mua hàng online. Thêm vào đó, nghiên cứu cũng đưa ra một số gợi ý cho các công ty bán lẻ sử dụng Internet để phát triển doanh nghiệp. Bài viết dựa trên một khảo sát online trên biểu mẫu Google, bảng hỏi thu thập dữ liệu từ 416 người tiêu dùng. Số liệu được xử lý bằng phần mềm IMB SPSS. Kết quả chỉ ra rằng có 1 mối quan hệ giữa tiếp thị số và hành vi mua sắm trực tuyến qua trung gian là các ứng dụng mua sắm, đồng thời, các ứng dụng mua sắm cũng có ảnh hưởng đáng kể lên hành vi mua hàng trực tuyến. Cuối cùng, nghiên cứu gợi ý cách làm nội dung tiếp thị hiệu quả hơn cho các trang mua sắm trực tuyến giúp quá trình mua hàng của người tiêu dùng đơn giản, thuận tiện hơn. Đồng thời, nghiên cứu này cũng cung cấp thông tin cho các doanh nghiệp bán hàng trực tuyến để ứng dụng thành công tiếp thị số như một chiến lược trong kế hoạch kinh doanh của họ, và nhận ra tầm quan trọng của tiếp thị số trong thị trường cạnh tranh ngày nay.
10
Ohkura, Satoshi, Toru Ichimaru, Fumiaki Itoh, Shuichi Matsuyama, and Hiroaki Okamura. "Further Evidence for the Role of Glucose as a Metabolic Regulator of Hypothalamic Gonadotropin-Releasing Hormone Pulse Generator Activity in Goats." Endocrinology 145, no. 7 (July 1, 2004): 3239–46. http://dx.doi.org/10.1210/en.2003-1516.
Full textAbstract:
Abstract The present study examined the relative importance of blood glucose vs. free fatty acids as a metabolic signal regulating GnRH release as measured electrophysiologically by multiple-unit activity (MUA) in the arcuate nucleus/median eminence region in ovariectomized, estradiol-treated goats. MUA was recorded before, during, and after: 1) cellular glucoprivation by peripheral infusion of 2-deoxy-d-glucose (2DG; 25, 50, and 75 mg/kg·h, iv); 2) peripheral hypoglycemia in response to various doses (15–195 mU/kg·h, iv) of insulin infusion; and 3) cellular lipoprivation induced by peripheral infusion of sodium mercaptoacetate (MA; 2.4 mg/kg·h alone or combined with 25 mg/kg·h of 2DG, iv), and effects on the interval of characteristic increases in MUA (MUA volleys) were examined. Infusion of the highest dose of 2DG increased the mean interval between MUA volleys, whereas the lower doses of 2DG had no effect on volley interval. The MUA volley intervals lengthened as insulin-induced hypoglycemia became profound. There was a negative correlation between MUA volley intervals and blood glucose concentrations during insulin infusion, and coinfusion of glucose with insulin returned the MUA volley interval to a normal frequency. Infusion of MA alone or MA with 2DG did not increase MUA volley intervals. These findings demonstrate that glucose availability, but not fatty acids, regulates the GnRH pulse generator activity in the ruminant. Glucose is considered a key metabolic regulator that fine-tunes pulsatile GnRH release.
Dissertations / Theses on the topic "MUA"
1
Tegan, Ty Preston Kawika. "Hale Mua: (En)gendering Hawaiian men." Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/1224.
Full textAbstract:
This dissertation examines the intersection of gender and culture in the process of identity formation among Kanaka 'Oiwi Maoli (Indigenous Hawaiian) men in the Hale Mua 0 Maui. Throughout the neocolonial Pacific, indigenous Oceanic men have engaged in gender practices that historically have had widely different consequences for their positions of power or marginality; the cases of Hawai'i and Aotearoa/New Zealand offer important insights into the gendered dynamics of colonialism, decolonization, and reclamation. Focusing in on a deeper history of colonization and revitalization at Pu'ukohola heiau (Kawaihae, Hawai'i), I highlight the ways in which the birth of a newly gendered tradition of bravery and warriorhood in Na Koa (The Courageous Ones) led to a reconsideration of men's roles in different sectors of the Hawaiian community. One outcome was the formation of the Hale Mua, or the "Men's House," on the island of Maui. Against the legacy of American colonialism and its concomitant discourses of death, disappearance, feminization, and domestication, the Hale Mua has endeavored to build strong, culturally grounded men that will take up their kuleana (rights and responsibilities) as members of their 'ohana (families) and the larger lahui (nation). In particular, I examine the role of discursive and embodied practices of ritual, performance, and narrative in the transformation, (re)definition, and enactment of their subjectivities as Hawaiian men. The processes through which the members of the group come to define, know, and perform these kuleana articulate with the larger projects of cultural revitalization, moral regeneration, spiritual/bodily healing, national reclamation, and the uncertain and ambiguous project of mental and political decolonization. Likewise, the very writing of this dissertation has fore-grounded both the possibilities and problematics of conducting indigenous anthropology and research at home.
2
Ching, Lena Lei. "Ka wa ma mua, ka wa ma hope." Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/6916.
Full textAbstract:
Hawaiian navigators oriented themselves without instruments by using a system based upon knowing where they came from and by having faith in the words of their ancestors. As a Hawaiian artist, I am embarking on a journey in which I orient myself in much the same way. When translated from our language, "ka wa ma mua" literally means "the time in front." However, in Hawaiian thinking, it describes the time that came before this time in which we live. In the same vein, "ka wa ma hope" literally means "the time in back" or from a Hawaiian perspective, the time which follows this time in which we live. "It is as if the Hawaiian stands firmly in the present, with his back to the future, and his eyes fixed upon the past, seeking historical answers for present-day dilemmas." (Kameʻeleihiwa, 1992) We Hawaiians view the world looking to that time that came before us because it is rich in knowledge. Looking to my ancestors and knowing the history of our people strongly influences how I view the world and contributes greatly to the forming of my relationship with it. I look to the past also to learn more about my Hawaiian identity. As a Hawaiian in today's world, I realize that part of the process requires that I engage in the task of decolonizing my mind. My thesis exhibition is an attempt to express through imagery one aspect of this decolonization. It is only one part of the process and one avenue of many through which an artist can express resistance to further erosion of our life ways. Looking to the past, recognizing that I was raised as a colonized person is one step towards better understanding the importance of my Hawaiian identity. Awareness of this part of my past is another step in the process of decolonization.iii, 35 leaves
3
Russell, Khyla J., and n/a. "Landscape : perceptions of Kai Tahu I Mua, Aianei, A Muri Ake." University of Otago. Department of Anthropology, 2001. http://adt.otago.ac.nz./public/adt-NZDU20070508.151703.
Full textAbstract:
This research is concerned with Kai Tahu experiences and understandings of the concept and use of the term, landscape. The term itself is one used variously to represent for us as Iwi, the land and the sea including flora and fauna. The Kai Tahu landscape is Papatuanuku, our cosmological mother. Particular areas used for the case studies include the following marae: Otakou, Karitane, Kaikoura, Tuahiwi, Ka marae e toru o Horomaka, Taumutu, Te Tai Poutini, Hukanui, Waihopai, Arowhenua, Oraka, Awarua and the many places of te rohe potae o Kai Tahu i Te Waipounamu. Material was drawn from literature, the participants formally interviewed and many from within and outside Kai Tahu rohe potae. All responses are used to illustrate the ways in which Kai Tahu and some of their non-Kai Tahu spouses express particular definitions of what for each, constitutes and is constituted in the landscape.
Kai Tahu participants� landscape definition includes whakapapa, placenames, identity (personal and cultural), spirituality and sustenance. Elements of these are present to a similar degree for some of the spouses, but not all. This seems largely dependent upon the degree to which they have participated in matters pertaining to Kai Tahu. Degrees of participation and connection may be applied to Tahu people alienated from their kaik, whether urbanised near or distantly domiciled.
Theoretical bases in literature from a number of disciplines are used to discuss perceptions of what anthropologists more usually term �place� and how Kai Tahu fit this or choose to fit the understanding of cultural others into our world view. The research also looks briefly at the environmental landscape and who presently has power and therefore mana over its use and or misuse, especially in relation to management of Papatuanuku.
Due to the [sic] of the type [sic] project this thesis is, it cannot finally conclude there is a single Kai Tahu or gender specific perception of landscape. This would never be provable in any circumstance, since it is not scientifically based. It does however, suggest there is an indigenous perspective of landscape that differs from certain Western thinking and within the indigenous perspective, a Kai Tahu epistemological understanding of the landscape based on our theory and knowledge of ourselves.
4
Wyeth, Emma Hana, and n/a. "Hauhaketia to wahia i mua i te takurua : Maori and genetic health research : a case study." University of Otago. Department of Biochemistry, 2008. http://adt.otago.ac.nz./public/adt-NZDU20080319.114119.
Full textAbstract:
This project was carried out under a broad theme of Maori health and investigates the genetics of rheumatoid arthritis (RA) and gout within two Maori case-control cohorts. In addition, it reports on the developmental stages of a whanau project focussing on the compilation of our whakapapa and collation of information relating to type 2 diabetes within the Parata whanau, which I whakapapa to. My conducting this research in light of me being Maori is also considered: much of the prevailing literature on Maori and science describes science as the handmaid of colonisation, and singles out genetic research as being "neo-colonial". I reject those that would label me a "sell-out" and show how my research is shaped by, and consistent with, the history of my immediate tipuna, and my iwi more generally, since European contact.
RA is an autoimmune disease of the joints and affects approximately 1% of the general population. There is currently very little data available on its prevalence in New Zealand although it is thought that it is similar to those of the rest of the world. Gout is the most common form of inflammatory arthritis in Caucasian males and recent data suggests a worldwide increase in prevalence in many populations. Gout is characterised by the deposition of monosodium urate or uric acid crystals in the joints, which produces an inflammatory response. In New Zealand, the prevalence of gout is estimated to be 3% in Caucasians and twice this in Maori. Both RA and gout are complex arthritic diseases and are influenced by a combination of genetic and environmental factors. It is likely that numerous genetic susceptibility loci are responsible for the genetic components of these diseases.
This project tests various genetic regions for susceptibility to or protection against both RA and gout in two separate Maori case cohorts and a common control cohort. To do this, the confounding factor of population stratification, resulting from population admixture, was overcome via developing a method specific for these Maori cohorts. This tool utilised genotype data from a set of unlinked genome-wide markers and the structure and STRAT software packages, allowing valid case-control studies to be carried out in the presence of population stratification. These data showed that four sub-populations exist in the Maori RA case-control cohort and three in the Maori gout case-control cohort.
A number of studies have confirmed the HLA region as the major genetic determinant of autoimmunity and recently, PTPN22 and CTLA-4 variants have been shown to be common to the onset of a number of autoimmune phenotypes. The IDDM6 region on chromosome 18 has also been implicated in type 1 diabetes, RA and autoimmune thyroiditis and contains a number of candidate genes for a role in RA, many of which were investigated in this thesis. Polymorphisms within the PTPN22, CTLA-4, BCL2, SMAD4, DCC, TNFRSF11A, PADI4, CCR5 and CCL3L1 genes were tested for association with RA in the Maori cohort (98 cases and 109 controls) with some significant association results obtained. The HLA-DRB1*02 and HLA-DRB1*08 loci were associated with the protection against and susceptibility for RA, respectively (P = 0.004 and 0.017). The deviation of CCL3L1 copy-number from the cohort mean (two copies) was also associated with the RA development. Copy-number <2 indicated association with protection against RA (P = 0.012) and copy-number >2 indicated association with susceptibility to RA (P = 0.002). However, it must be stressed that these results were obtained without accounting for the presence of population stratification.
The organic anion transporter (OAT) and the urate transporter 1 (URAT1) genes, involved in the regulation of blood urate levels, are members of the solute carrier transporter (SLC) family and provide good candidates for a role in gout. A number of polymorphisms within the OAT, URAT1 and the SLC5A8 genes were tested for association with gout in the Maori cohort (72 cases and 109 controls) with some success. The SLC5A8 rs1709189 SNP was significantly associated with gout in this cohort (P = 0.004). Polymorphisms within two alcohol dehydrogenase (ADH) genes were also tested for association due to their role in alcohol metabolism and the association between alcohol consumption and gout. The ADH2 rs1229984 SNP was also significantly associated with gout in this cohort (P = 0.012). These significant results were obtained after population stratification was taken into account.
The data presented in this thesis confirm the presence of population stratification in the two Maori case-control cohorts and demonstrate some association of the HLA-DRB1 region and CCL3L1 with RA and the SLC5A8 and ADH2 genes with gout. An extensive whakapapa of our whanau has also been compiled and associated type 2 diabetes information collected. However, this is by no means a completed task and work will continue on this project under the guidance of the Parata whanau.
5
Ling, Lorraine Ph D. Massachusetts Institute of Technology. "Design framework of the MuA remodeling signal that confers preferential complex disassembly by the AAA+ unfoldase ClpX." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/92593.
Full textAbstract:
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2014.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 77-87).
The cell employs many classes of molecular chaperones to facilitate proteins in adopting the proper structure and preventing non-functional and potentially toxic non-native states. The Clp/Hsp100 family of ATPases are unfolding chaperones that remodel macromolecular complexes and facilitate ATP-dependent protein degradation. They are members of the superfamily of AAA+ enzymes (ATPases Associated with various cellular Activities), which is conserved across all kingdoms of life. Efficient selection of multimeric protein complexes over constituent subunits is key to successful remodeling and disassembly reactions. Using E.coli ClpX as a model for AAA+ ATPases, I characterized the mechanism by which ClpX discriminates between two oligomeric states of one of its natural multimeric substrates, phage MuA tranposase. I elucidated many strategies for ClpX's preference for the assembled Mu transpososome (MuA complex) over unassembled subunits. First, the target substrate makes multiple weak interactions with the AAA+ ATPase via the pore in the conserved ATPase domain and a class-specific auxiliary domain. Second, recognition tags should be at the weaker end of the affinity spectrum to allow effective synergy of multiple tags in the assembled complex. Third, multimeric complexes can "divide the labor" of making these interactions among their subunits. Thus the holistic complex-specific targeting signal is accessible only in the assembled complex. The work of this thesis has provided a framework to understand the design of recognition signals that specify and target macromolecular complexes to unfolding chaperones and remodelers of the AAA+ superfamily.
by Lorraine Ling.
Ph. D.
6
Lämsä, J. (Jani), and L. (Liisi) Pasanen. "”Et sää voi mua määrätä, kun sää et oo mun äiti”:opettajien näkemyksiä koulujen työrauhasta ja opettajan sukupuolen merkityksestä." Master's thesis, University of Oulu, 2017. http://jultika.oulu.fi/Record/nbnfioulu-201706022414.
Full textAbstract:
Tiivistelmä. Ongelmat työrauhassa aiheuttavat opettajalle suurta päänvaivaa. Vaikka aiheena työrauha on paljon tutkittu, vähemmän aihetta on tarkasteltu vastikään työelämään siirtyneiden opettajien kannalta tai sukupuolen näkökulmasta. Tämän tutkimuksen tarkoituksena on kartoittaa nuorten mies- ja naisopettajien näkemyksiä työrauhasta ja sen häiriöistä. Lisäksi tutkimuksessa tarkastellaan opettajien näkemyksiä siitä, millainen merkitys opettajan sukupuolella on hänen kykyynsä ylläpitää työrauhaa. Tutkimuksen teoreettisessa viitekehyksessä työrauhaa ja sen häiriöitä tarkastellaan erityisesti aloittelevien luokanopettajien näkökulmasta. Lisäksi auktoriteetin käsitettä lähestytään tarkemmin työrauhan ylläpitämisen kannalta. Koulussa nais- ja miesopettajat ymmärretään erilaisiksi paitsi käsityksiltään työrauhasta, myös toimintatavoiltaan työrauhatilanteissa.
Tämä tutkimus on luonteeltaan laadullinen ja se on toteutettu laadulliselle tutkimukselle ominaisten käytänteiden mukaisesti. Aineiston olemme keränneet puolistrukturoidun teemahaastattelun avulla kahdeksalta alle viisi vuotta työelämässä olleelta luokanopettajalta. Opettajista neljä oli naisia ja neljä miehiä, ja he työskentelivät pääosin Pohjois-Pohjanmaan alueella. Aineisto analysoitiin sisällönanalyysin avulla.
Tutkimustuloksissa nuoret nais- ja miesopettajat käsittivät työrauhan subjektiiviseksi ja tilannesidonnaiseksi ilmiöksi. Työrauhahäiriö määriteltiin työrauhaa päinvastaiseksi asiaksi, jonka syitä haettiin koulun ulkopuolisista ja sisäisistä tekijöistä. Häiriöiden vaikutukset nähtiin erityisesti oppilaiden oppimisessa ja opettajan työhyvinvoinnissa. Siinä missä miesopettajilla häiriöt näkyivät työssä jaksamisen ongelmina, naisilla ne vaikuttivat alentavasti minäkuvaan. Työrauhan ylläpitämisessä nais- ja miesopettajat nähtiin toimintatavoiltaan erilaisina. Häiriöihin puuttumisessa miesopettajien nähtiin käyttävän usein suoraa puhetta ja naisopettajien nojautuvan pehmeämpiin keinoihin. Tehtävänä työrauhan ylläpito koettiin lähtökohtaisesti helpompana miehille ja naisille työläämpänä saavuttaa. Tätä opettajat perustelivat miehen luontaisella auktoriteetilla ja maskuliinisiksi mielletyillä ominaisuuksilla.
Tutkimuksen johtopäätöksenä opettajien käsitykset työrauhasta olivat pitkälti nykykoulutuksen ihanteiden mukaisia. Työrauhan merkitystä ja vaikutuksia tarkasteltiin ensisijaisesti oppilaan näkökulmasta, sitten opettajan. Opettajan persoona ja työkokemus nähtiin tärkeimpinä työrauhan edistäjinä, mutta sukupuolen merkityksessä näkyi vahva sukupuoliroolien periytyvyys vuosikymmenten takaa.
7
Cekic, Can Eyup. "Savoir Vivre Cosmopolite: Ahmed Midhat'." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/12610918/index.pdf.
Full textAbstract:
This study aims to reevaluate Ahmed Midhat&rsquos treatises on Ottoman society by revealing his exceptional objectives, which recently have been used in contemporary interdisciplinary studies concerning the 19th century Ottoman social transformation. In view of that, the thesis is formed as a re-reading of Ahmed Midhat&rsquo
s etiquette book, titled Avrupa Adab-i MuaSereti yahud Alafranga, according to some recent debates like that of occidentalism, geographic mapping of culture and civilization, the question of cosmopolitanism and elitism, everyday life practices. The most important aim of this thesis study is to expose the ability and the tool-kit of an Ottoman intellectual, who claims himself belong to the Ottoman Nation, making use of the knowledge of the west for domestic politics and arguments in order to propose and create a genuine, self-governing and permanent Ottoman culture. Besides the knowledge of the west, Ahmed Midhat&rsquo
s Alafranga represents a very significant literary form that demonstrates the modern change in the intellectual production in Europe. In that perspective, exposing his motivations behind writing an etiquette manual, a literary form which is related to the modern idea of creating a mechanism of self-control for the individuals, and at large for the society itself, is significant the ways in which these motivations represent the ideas of a Tanzimat intellectual on the modernization of the Ottoman society, considering his sympathy for the Hamidian worldview and modernization projects.
8
Pires, Ana Luísa de Oliveira Gonçalves. "Present, imagination and memory in Zakes Mda and Mia Couto." Doctoral thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/3946.
Full textAbstract:
Doutoramento em LiteraturaApesar de marcadas por contextos históricos e culturais distintos, é possível observar nas obras de dois dos autores mais significativos da África do Sul e de Moçambique, Zakes Mda e Mia Couto respectivamente, perspectivas semelhantes no que diz respeito à recuperação das memórias históricoculturais e à sua contribuição para a construção e compreensão das identidades pós-coloniais. Através da ficção, Zakes Mda e Mia Couto combinam a ligação da História a factos concretos com a necessidade de revelação associada à memória, criando assim espaços importantes para a discussão de algumas das mais complexas questões colocadas às identidades pós-coloniais. Para além dos contextos políticos, culturais e históricos que caracterizam e distinguem as literaturas sul-africana e moçambicana, tanto Zakes Mda como Mia Couto assumem nas suas obras a necessidade de analisar as identidades pós-coloniais contemporâneas dos dois países através da recuperação das suas memórias históricas.
In spite of the specificities pertaining to South African and Mozambican history and culture, in the novels of two of the most significant literary representatives of those Southern African nations, Zakes Mda and Mia Couto respectively, it is possible to observe similar perspectives regarding the recovery of cultural memories and histories and their contribution toward the construction, development and understanding of postcolonial identities. Through fiction, Zakes Mda and Mia Couto combine history’s concern with concrete facts and memory’s attachment to disclosure, opening important spaces to debate some of the most complex questions posed to African postcolonial identities. Beyond the distinctive political, cultural and historical contexts that have shaped South African and Mozambican literatures, both Zakes Mda and Mia Couto assume in their novels the need to examine contemporary South African and Mozambican postcolonial identities by resorting to the reclamation of their historical memories.
9
Rådén, Cecilia. "”Smutsiga män och goda kvinnor” : En genusstudie om Moa Martinsons män i Mia-serien." Thesis, Stockholms universitet, Institutionen för litteraturvetenskap och idéhistoria, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-92557.
Full textAbstract:
Uppsatsen syftar till en undersökning av Moa Martinsons framställning av männen i serien om Mia Stenman som kan öppna upp en ny tolkning. Genom ett genusperspektiv har jag tittat på strukturen i hur männens utseende och personlighet porträtteras och hur detta påverkar Mia. Sedan har jag skildrat Martinsons politiska liv och behandlat delar av hennes relationer för att uppnå en bättre tolkning. Analysen av ett urval av män i hela serien, mestadels hennes styvfader, då han är den som figurerar mest hela serien igenom, visar på hur olika de framställs. Gemensamt har de allra flesta att de porträtteras mycket negativt, genom att utmåla framträdande drag i ansiktet och en personlighet som inte är så smickrande. De få som inte beskrivs som ovan nämnt, äger i stället en faderlig ton, alternativt är så underlägsna att Mia inte förmår sig att vara elak mot dem. Allt eftersom Mia blir äldre, får hon en mer neutral ton mot männen, trots att hon behåller sin självständighet och står fast vid att hon inte vill gifta sig. Mia lider av en stark svartsjuka som kan ha lett till att hon på äldre dagar får en starkt maskulin sida som är mer aggressiv, ironiskt nog, just mot det maskulina. Männens fysiska existens sammanfaller med det sociala och politiska som sker runt omkring dem i världen. Med anledning av detta skapade Martinson en polemik mot männen, vars identitet hon trampade på när hon som självständig kvinna gav ut en roman, som tillhörde den genre som bara män tidigare blivit publicerade inom. Detta återskapas sedan i serien, genom att Mia varken blir, eller låter sig bli omhändertagen av några män, utom de hon själv väljer, och knappt ens då. Martinsons personliga agenda tränger oupphörligt fram när hon vill stärka kvinnorna och påvisa sanningen ur en kvinnas perspektiv.
10
Afonso, Carla Winter. "Master in Bussiness Administration (MBA) versus Mestrado Profissionalizante em Administração (MPA): diferenças e similaridades." reponame:Repositório Institucional do FGV, 2005. http://hdl.handle.net/10438/3341.
Full textAbstract:
Made available in DSpace on 2009-11-18T18:56:19Z (GMT). No. of bitstreams: 1
Dissertacao versao final.pdf: 440712 bytes, checksum: abdc8fffa15d45d503091f4f9e54f600 (MD5)
Previous issue date: 2005This study had for objective to identify the similarities and differences between Executives Programs (Mestrado Modalidade Profissional) and Master in Business Administration (MBAs), specializations lato sensu. In order to achieve these objectives bibliographical and field researches were developed. The bibliographical research allowed to identify the uprising contradiction between Executive Education and Academic Education. The field research allowed to verify the differences and concrete similarities perceived by pupils and coordinators. In the field, interviews in depth and applied half-structuralized questionnaires had been carried through. The interviews had been taken the effect with the coordinators of the MBA courses and Mestrado Profissional/Executivo of five institutions. The half-structuralized questionnaires had been applied in two institutions, in the pupils of the groups of Mestrado Profissional/Executivo and MBA. The results of the interviews and of the questionnaires had been enclosed in one of the six categories previously defined in the study. The research corroborated the initial assumption, that detaches the differences between the cited courses.
Esta pesquisa teve por objetivo identificar as similaridades e diferenças entre os cursos de Mestrado Profissional e MBA, especializações lato sensu. Para possibilitar a identificação e análise foram utilizadas como meio, pesquisa de campo e bibliográfica. O levantamento bibliográfico permitiu identificar o surgimento da contradição entre Educação Executiva, de cunho prático/ profissional e Educação Acadêmica. A pesquisa de campo permitiu verificar as diferenças e similaridades concretas percebidas por alunos e coordenadores. No campo foram realizadas entrevistas em profundidade e aplicado questionários semi-estruturados. As entrevistas foram levadas a efeito com os coordenadores dos cursos de MBA e Mestrado Profissional/Executivo de cinco instituições. Os questionários semi-estruturados foram aplicados em duas instituições, nos alunos das turmas do Mestrado Profissional/Executivo e MBA. Os resultados das entrevistas e os dos questionários foram incluídos em uma das seis categorias previamente definidas no estudo. A pesquisa corroborou a suposição inicial, que destaca as diferenças entre os cursos citados.
Books on the topic "MUA"
9
Mua ŭi pit: Mua Pang Yu-ryong Andŭrea Sinbu ŭi haesŏkchŏk saengaesa. Sŏul-si: BG Puk Kaellŏri, 2011.
Find full textBook chapters on the topic "MUA"
1
Stettner, Johanna, Paul Frank, Thomas Griesser, Gregor Trimmel, Robert Schennach, Roland Resel, and Adolf Winkler. "Characterization of 11-MUA SAM formation on gold surfaces." In Springer Proceedings in Physics, 101–5. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-95930-4_17.
Full text
2
Chikuni, A. C. "Conservation status of mopane woodlands in Malawi: a case study of Mua-Tsanya Forest Reserve." In The Biodiversity of African Plants, 250–58. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0285-5_33.
Full text
3
Frank, P., F. Nussbacher, J. Stettner, and A. Winkler. "SAMs of 11-MUA grown on polycrystalline Au-foils by physical vapor deposition in UHV." In Springer Proceedings in Physics, 107–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-95930-4_18.
Full text
4
Hesse, Nils. "MAU-MAU." In Spielend gewinnen, 185–86. Wiesbaden: Springer Fachmedien Wiesbaden, 2014. http://dx.doi.org/10.1007/978-3-658-04441-1_38.
Full text
5
Horne, Gerald. "“Mau Mau”." In Mau Mau in Harlem?, 115–28. New York: Palgrave Macmillan US, 2009. http://dx.doi.org/10.1057/9780230101043_10.
Full text
6
Horne, Gerald. "Mau Mau Looms." In Mau Mau in Harlem?, 89–100. New York: Palgrave Macmillan US, 2009. http://dx.doi.org/10.1057/9780230101043_8.
Full text
7
Godfrey, Menna. "Mud, glorious mud! Mud kitchensand more." In Young Children’s Play and Creativity, 189–98. Abingdon, Oxon ; New York, NY : Routledge, 2018.: Routledge, 2017. http://dx.doi.org/10.4324/9781315446844-16.
Full text
8
Horne, Gerald. "Introduction." In Mau Mau in Harlem?, 1–17. New York: Palgrave Macmillan US, 2009. http://dx.doi.org/10.1057/9780230101043_1.
Full text
9
Horne, Gerald. "The United States Arms the Settlers?" In Mau Mau in Harlem?, 129–41. New York: Palgrave Macmillan US, 2009. http://dx.doi.org/10.1057/9780230101043_11.
Full text
10
Horne, Gerald. "“Mau Mau”—to Little Rock." In Mau Mau in Harlem?, 143–56. New York: Palgrave Macmillan US, 2009. http://dx.doi.org/10.1057/9780230101043_12.
Full textConference papers on the topic "MUA"
1
Wu, Chia-Che, Ping-Kuo Tseng, and Ching-Hsiu Tsai. "Improving Adhesion Density and Coverage Uniformity of Antibody-Antigen Binding on a Sensor Surface Using U-Type, T-Type and W-Type Microfluidic Devices." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-47528.
Full textAbstract:
Usually microorganisms, molecules, or viruses in the fluidic environment are at very low Reynolds numbers because of tiny diameters. At very low Reynolds numbers, viscous forces of molecules and viruses will dominate. Those micro- or nanoparticles will stop moving immediately when flows cease and drag forces disappear, those phenomena were discovered by the fluorescent particle experiment. Of course, molecules and viruses are still subject to Brownian motion and move randomly. In order to increase the adhesion density of micro- and nanoparticles on sensor’s surface, designs of the flow movements in microfluidic channel is proposed. Adhesion density of linker 11-mercaptoundecanoic acid (MUA) and Turnip yellow mosaic virus (TYMV) with specific quantum dots were measured by confocal microscope. Fluorescent intensity and coverage of quantum dots are used to identify the adhesion density quantitatively. Results show that TYMV and MUA layers disperse randomly by dipping method. Fluorescent intensity of quantum dots; i.e. relative to the amount of MUA and TYMV; were 2.67A.U. and 19.13A.U., respectively, in W-type microfluidic devices to contrast just 1.00A.U. and 1.00A.U., respectively, by dipping method. Coverage of MUA and TYMV were 80∼90% and 70∼90%, respectively, in W-type microfluidic channel to contrast just 20∼50% and 0∼10%, respectively, by dipping method.
2
Yang, Chih-Hui, Keng-Shiang Huang, Sheng-Ji Lee, Kuo-Chin Lin, and Yu-Cheng Lin. "Water-soluble (MUA-coated) quantum dots: physicochemical characterization and application." In MOEMS-MEMS 2007 Micro and Nanofabrication. SPIE, 2007. http://dx.doi.org/10.1117/12.708787.
Full text
3
Wu, Chia-Che, Ping-Kuo Tseng, Meng-Jhu Hou, and Ching-Hsiu Tsai. "Adhesive Density of 11-Mercaptoundecanoic Acid (MUA) and Turnip Yellow Mosaic Virus (TYMV) in Microfluidic Channels." In ASME 2009 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/detc2009-86222.
Full textAbstract:
Recently, there has been an increasing interest to develop rapid, reliable and low-concentration detection methods of micro-organisms involved in bioterrorism, food poisoning, and clinical problems. How to detect virus at concentration below the threshold will be challenging with respect to specificity, selectivity, and sensitivity. Among all parameters, sensitivity is probably the most critical consideration. If the sensitivity is not satisfied for real-time detection, researchers need to duplicate numerous numbers of viruses. However, it will substantially increase processing times and experimental hazard. To increase the sensitivity of virus sensors, this paper discusses how to increase the density of linkers and viruses on sensor’s surface in the microfluidic channels. In the future, researcher could use emerging technology, such as PT-PCR, QCM, C-V and I-V measurements, etc, to detect viruses on sensor’s surface. Usually microorganisms, molecules, or viruses in the fluidic environment are at very low Reynolds numbers because of tiny diameters. At very low Reynolds numbers, viscous forces of molecules and viruses will dominate. Those micro- or nanoparticles will stop moving immediately when flows cease and drag forces disappear. Of course, molecules and viruses are still subject to Brownian motion and move randomly. In order to increase the adhesion density of micro- and nanoparticles on sensor’s surface, designs of the flow movements in microfluidic channel is proposed. Adhesion density of linker 11-mercaptoundecanoic acid (MUA) and turnip yellow mosaic virus (TYMV) with specific quantum dots were measured by confocal microscope. Results show that TYMV and MUA layers disperse randomly by dipping method. Infusion rate, flow rate, and transverse flow could affect the adhesion densities of recognition layers on sensors’ surface. Adhesion densities of MUA and TYMV can be reached 70∼80% by microfluidic method to contrast just 10% by dipping method.
4
Waipara, Zak. "Ka mua, ka muri: Navigating the future of design education by drawing upon indigenous frameworks." In Link Symposium 2020 Practice-oriented research in Design. AUT Faculty of Design and Creative Technologies, 2020. http://dx.doi.org/10.24135/lsa.4.
Full textAbstract:
We have not yet emerged into a post-COVID world. The future is fluid and unknown. As the Academy morphs under pressure, as design practitioners and educators attempt to respond to the shifting world – in the M?ori language, Te Ao Hurihuri – how might we manage such changes? There is an indigenous precedent of drawing upon the past to assist with present and future states – as the proverb ka mua ka muri indicates, ‘travelling backwards into the future,’ viewing the past spread out behind us, as we move into the unknown. Indigenous academics often draw inspiration from extant traditional viewpoints, reframing them as methodologies, and drawing on metaphor to shape solutions. Some of these frameworks, such as Te Whare Tapa Wh?, developed as a health-based model, have been adapted for educational purposes. Many examples of metaphor drawn from indigenous ways of thinking have also been adapted as design or designrelated methodologies. What is it about the power of metaphor, particularly indigenous ways of seeing, that might offer solutions for both student and teacher? One developing propositional model uses the Pacific voyager as exemplar for the student. Hohl cites Polynesian navigation an inspirational metaphor, where “navigating the vast Pacific Ocean without instruments, only using the sun, moon, stars, swells, clouds and birds as orienting cues to travel vast distances between Polynesian islands.”1 However, in these uncertain times, it becomes just as relevant for the academic staff member. As Reilly notes, using this analogy to situate two cultures working as one: “like two canoes, lashed together to achieve greater stability in the open seas … we must work together to ensure our ship keeps pointing towards calmer waters and to a future that benefits subsequent generations.”2 The goal in formulating this framework has been to extract guiding principles and construct a useful, applicable structure by drawing from research on two existing models based in Samoan and Hawaiian worldviews, synthesised via related M?ori concepts. Just as we expect our students to stretch their imaginations and challenge themselves, we the educators might also find courage in the face of the unknown, drawing strength from indigenous storytelling. Hohl describes the advantages of examining this approach: “People living on islands are highly aware of the limitedness of their resources, the precarious balance of their natural environment and the long wearing negative effects of unsustainable actions … from experience and observing the consequences of actions in a limited and confined environment necessarily lead to a sustainable culture in order for such a society to survive.”3 Calculated risks must be undertaken to navigate this space, as shown in this waka-navigator framework, adapted for potential use in a collaborative, studio-style classroom model. 1 Michael Hohl, “Living in Cybernetics: Polynesian Voyaging and Ecological Literacy as Models for design education, Kybernetes 44, 8/9 (October 2015). https://doi.org/ 10.1108/K-11-2014-0236. 2 Michael P.J Reilly, “A Stranger to the Islands: Voice, Place and the Self in Indigenous Studies” (Inaugural Professorial Lecture, University of Otago, Dunedin, New Zealand, 2009). http://hdl.handle.net/10523/5183 3 Hohl, “Living in Cybernetics”.
5
Nhuần, Nguyễn Thị, and Đỗ Thị Xuyến. "PHÂN LOẠI HỌ MUA (Melastomataceae JUSS.) Ở VƯỜN QUỐC GIA TAM ĐẢO, TỈNH VĨNH PHÚC." In HỘI NGHỊ KHOA HỌC QUỐC GIA VỀ NGHIÊN CỨU VÀ GIẢNG DẠY SINH HỌC Ở VIỆT NAM. Nhà xuất bản Khoa học tự nhiên và Công nghệ, 2020. http://dx.doi.org/10.15625/vap.2020.00049.
Full text
6
Cai, Changsi, Ying Zhao, Liming Li, Kaijie Wu, Xinyu Chai, and Qiushi Ren. "Multi-channel Microelectrode Recording of MUA in Cat Visual Cortex by Electrical Stimulation in Optic Nerve." In 2007 IEEE/ICME International Conference on Complex Medical Engineering. IEEE, 2007. http://dx.doi.org/10.1109/iccme.2007.4381954.
Full text
7
Salverson, Lynsey A. M., Nader Saniei, Mel Mendelson, and Michelle Lum. "An Engineering Approach Investigating the Uptake and Phytotoxicity of One Type of Engineered Nanoparticle (CdSe/ZnS Quantum Dots) by Solanum Lycopersicum." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14032.
Full textAbstract:
The novel and extraordinary physiochemical properties of engineered nanoparticles (ENPs) is certain, yet, at the same time, their unique characteristics raise growing concerns regarding potentially adverse effects on biological and ecological systems. It is becoming increasingly evident, that before the full potential of nanotechnology can be realized, standardized characterization of ENPs behavior, fate, and their effects in the ecosystem are essential, to ensure the safe manufacturing and use of ENP products. Otherwise, the promise of such extraordinary advancements may find itself limited to applications such as electronics, and sporting equipments, industries in which it currently resides. The current toxicity profile of engineered nanomaterials is not only preliminary, but highly variable amongst researchers. Emphasizing the great need to develop a highly organized, efficient, and precise approach to assess the hazardous potential ENPs may pose, and address the safety concerns surrounding and limiting nanotechnology. In response to such concerns, the present study took an engineering approach, in an otherwise traditionally viewed discipline, to assess the potential impact of engineered nanoparticles on tomato (Solanum lycopersicum) seedlings, by implementing a full factorial design of experiment (FDOE) in an effort to identify what factors, and their interactions, have a significant (p ≤ 0.05) effect on root and shoot elongation, and if any observed effects are a result of particle uptake, evaluated via fluorescence microscopy imaging. Therefore, the goal of our study was to design and implement an efficient, effective, and precise method to assess the effect of one type of ENP, water-soluble CdSe/ZnS quantum dots, using Solanum lycopersicum as our model organism, one of 10 species recommended by the Unites States Environmental Protection Agency (US EPA) for use in phytotoxicity studies, via a methodology we believe novel to nanotechnology. By implementing factorial experimental design methodologies, not only are we efficiently identifying the factors that affect phytotoxicity, we are providing, for the first time to our knowledge, the first scientific data to report the significant interaction effects between the factors responsible for ENP toxicity. Water soluble (MUA) CdSe/ZnS quantum dots used in our study had a negative influence on root and shoot lengths of tomato seeds exposed for 3 and 6 days. The observed influence depended on (MUA) CdSe/ZnS concentration and QD exposure time. The importance of the factor effects were examined via analysis of variance (ANOVA), t-tests, confidence intervals, and normal plot statistical analyses. The findings concluded that factors B, C, and the BC-interaction (CdSe/ZnS: Exposure time, concentration, and exposure time–concentration interaction) significantly (p ≤ 0.05) affected root and shoot lengths of tomato seedlings. Thus, factors A, AB, AC, and ABC (CdSe/ZnS QD: Size, size–concentration, size-exposure time, and size-concentration-exposure time interactions) were not found to have a significant effect on root and shoot lengths of tomato seedlings, and ultimately eliminated from our model. After analyzing the interaction plots, it became evident that low percentages of root reduction are obtained at low concentration levels for short lengths of time; thus, to obtain the least amount of phytotoxic effects one would set factors B (concentration) and C (exposure time) to their low levels, 125 mg/L for 3 days, respectively. Alternatively, high percentages of root reduction are obtained at high concentration levels for long lengths of time; thus, to obtain the greatest phytotoxic effect one would set factors B and C to their high levels, 1000 mg/L for 6 days, respectively. This indicates that as exposure time increases, root reduction increases; thus, phytotoxicity increases. Since our study attempted to realize which factors minimize phytotoxicity effects of one type of ENP, these findings suggest that to minimize phytotoxicity effects (i.e. maximize root length or minimize percent of root reduction) of (MUA) CdSe/ZnS QDs on tomato seeds, set factors B and C (QD concentration and exposure time) to their low levels; that is, expose tomato seeds to 125 mg/L of QD solution for a maximum of 3 days. These settings will yield the least amount of root reduction (5.15%) and; thus, phytotoxicity effects will be minimized. With regard to tomato roots ability to uptake MUA QDs, our results contribute to the literature by reporting uptake possible. Although we did see particles inside the root, it was sporadic and difficult to quantify. As to whether it was intracellular (within the cell) or intercellular (in the spaces between the cells, i.e., outside the cells) we could not conclude with certainty, although we suspect the QDs were intercellular. Thus, we highly recommend future experiments involving cross sections and more in-depth microscopy imaging. Additionally, although the results of our experiment failed to support that particle size (t = 2.13; d.f. = 1; p = 0.065) or the particle size-exposure time interaction (t = 2.17; d.f. = 1; p = 0.062) had a significant effect on root and shoot lengths of tomato seedlings, due to the small p-value associated with both test statistics, it is our belief that particle size and the particle size-exposure time interaction may, in fact, be a real effect; thus, further investigation is recommended.
8
Kawasaki, Yoshiki, Masahiko Karube, Aizoh Kubo, B. S. Khargonkar, N. K. Rao, and Vikas Manjrekar. "Development of Transmission and Transfer Gear With Locomotive Noise (Whine Noise)." In ASME 2000 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/detc2000/ptg-14447.
Full textAbstract:
Abstract Between 1990 and 1995, ISUZU (ISZ) automobiles RV lines, specifically Trooper with MUA Type Transfer (Fig.1), had problems with loud locomotive noise, also known as whine noise. In July 1992, HINDUSTAN MOTORS (HM) found the same problem with its 4X2 MSG Type Transmission (Fig.2).† At first, we looked to the gear precision and tooth contact pattern on both good and defective transfer units for the cause of the whine noise; unfortunately, after investigation, nothing was found. In total, we checked the involute helicoid, outer shape of shaft and all faces of gear and root of gear. Consequently, we found the whine noise was caused by the root running out of gear resulting in an imbalance in the face and the shape of shaft, causing each to run out. At the same time, we found that minimized the unbalance value will solve the whine noise issue. We used two test units (good and defective) to conduct the research and to resolve the whine noise problem.
9
Wang, Wei-Jhen, Chia-Hwa Lee, Chin-Wen Li, Stephen Liao, Fuh-Jyh Jan, and Gou-Jen Wang. "Direct Label Free Detection of Orchid Virus Using a Micro/Nano Hybrid Structured Biosensor." In ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-97198.
Full textAbstract:
Abstract In this study, a label-free detection approach for effective detection of the odontoglossum ringspot virus (ORSV) infected orchids has been developed. We used semiconductor fabrication process to fabricate 1,810 micro/nano hybrid structured sensing electrodes on a 8 inch reclaimed wafer. The self-assembled monolayer (SAM) process was then employed to sequentially modify the electrode surface with 11-mercaptoundecanoic acid (11-MUA), 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC)/ N-hydroxysuccinimide (NHS), anti-ORSV, and ORSV. EIS was conducted for the ORSV concentration detection. Experimental results demonstrated that the ORSV concentration in a virus infected orchid leaf could be effectively detected. When compared with the ELISA kit, our device possesses a wider linear detection range (0.5–50,000 ng/mL) and a higher sensitivity. The specificity of our device on ORSV detection was also confirmed. Our sensing device retains advantages, such as label-free, lower amounts of the antibody and target sample required, low detection time, and a wider linear detection range. Those results imply the feasibility of our sensing device in field applications.
10
Jiang, Zhen, Wei Li, Daniel W. Apley, and Wei Chen. "A System Uncertainty Propagation Approach With Model Uncertainty Quantification in Multidisciplinary Design." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34708.
Full textAbstract:
The performance of a multidisciplinary system is inevitably affected by various sources of uncertainties, usually categorized as aleatory (e.g. input variability) or epistemic (e.g. model uncertainty) uncertainty. In the framework of design under uncertainty, all sources of uncertainties should be aggregated to assess the uncertainty of system quantities of interest (QOIs). In a multidisciplinary design system, uncertainty propagation refers to the analysis that quantifies the overall uncertainty of system QOIs resulting from all sources of aleatory and epistemic uncertainty originating in the individual disciplines. However, due to the complexity of multidisciplinary simulation, especially the coupling relationships between individual disciplines, many uncertainty propagation approaches in the existing literature only consider aleatory uncertainty and ignore the impact of epistemic uncertainty. In this paper, we address the issue of efficient uncertainty quantification of system QOIs considering both aleatory and epistemic uncertainties. We propose a spatial-random-process (SRP) based multidisciplinary uncertainty analysis (MUA) method that, subsequent to SRP-based disciplinary model uncertainty quantification, fully utilizes the structure of SRP emulators and leads to compact analytical formulas for assessing statistical moments of uncertain QOIs. The proposed method is applied to a benchmark electronics packaging problem. To demonstrate the effectiveness of the method, the estimated low-order statistical moments of the QOIs are compared to the results from Monte Carlo simulations.
Reports on the topic "MUA"
1
Margolis, D., M. Risher, B. Ramakrishnan, A. Brotman, and J. Jones. SMTP MTA Strict Transport Security (MTA-STS). RFC Editor, September 2018. http://dx.doi.org/10.17487/rfc8461.
Full text
2
Wroblewski, Angela, and Victoria Englmaier. Absolventinnenbefragung muv. IHS - Institute for Advanced Studies, February 2017. http://dx.doi.org/10.22163/fteval.2017.499.
Full textAbstract:
Despite some successes, however, there are still barriers for women at universities, which are reflected in the so-called "leaky pipeline", i.e. a decreasing proportion of women the higher their position in the science system. The University of Vienna is also characterised by a pronounced leaky pipeline. The mentoring programme of the University of Vienna - muv - was launched to counteract this development and to support women in entering an academic career. The programme has been continuously evaluated and further developed. This report continues this tradition and provides input for a discussion on the further development of the programme.
3
Fries, David, R. T. Short, and L. Langebrake. ASCI muP: Fieldable Microsystems. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada627599.
Full text
4
Walsh, Mark. Mud, Twigs, and Clover. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.7057.
Full text
5
Nelson, J. V. Irradiation data for the MFA-1 and MFA-2 tests in the FFTF. Office of Scientific and Technical Information (OSTI), April 1997. http://dx.doi.org/10.2172/16897.
Full text
6
Kippen, Karen Elizabeth. MPA Materials Matter October 2018. Office of Scientific and Technical Information (OSTI), October 2018. http://dx.doi.org/10.2172/1475330.
Full text
7
Kippen, Karen Elizabeth. MPA Materials Matter January 2019. Office of Scientific and Technical Information (OSTI), January 2019. http://dx.doi.org/10.2172/1492562.
Full text
8
Kippen, Karen E. MPA Materials Matter March 2014. Office of Scientific and Technical Information (OSTI), March 2014. http://dx.doi.org/10.2172/1126676.
Full text
9
Kippen, Karen E. MPA Materials Matter May 2014. Office of Scientific and Technical Information (OSTI), May 2014. http://dx.doi.org/10.2172/1133764.
Full text
10
Kippen, Karen. MPA, Materials Physics and Applications. Office of Scientific and Technical Information (OSTI), August 2014. http://dx.doi.org/10.2172/1148946.
Full text