Relevant bibliographies by topics / Mucosal immunity / Dissertations / Theses
To see the other types of publications on this topic, follow the link: Mucosal immunity.

Dissertations / Theses on the topic 'Mucosal immunity'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Mucosal immunity.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Tjärnlund, Anna. "Mucosal Immunity in Mycobacterial infections." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-6782.

Full text
Abstract:
<p>More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB, caused by the bacterium <i>Mycobacterium tuberculosis</i>, is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. The currently used vaccine, BCG, is administered parenterally and induces a systemic immune response. However, it fails to protect against pulmonary TB, thereby raising the question whether vaccination targeting the mucos
APA, Harvard, Vancouver, ISO, and other styles
2

Rahman, Muhammad Jubayer. "Mucosal immunity against mycobacterial infection." Doctoral thesis, Stockholms universitet, Wenner-Grens institut, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-39170.

Full text
Abstract:
This thesis aimed to the identification of immune biomarkers of mycobacterial infection for better diagnosis of tuberculosis (TB) and also focused on new vaccination strategies with a particular emphasis on the immune responses in the respiratory tract using murine models. Since the lung is the natural habitat for the M. tuberculosis, we reasoned that immune responses detected locally in the lungs would be good correlates of infection (Paper I). Likewise, immune responses induced in the respiratory tract following immunization would be more effective against mycobacterial infection. We showed
APA, Harvard, Vancouver, ISO, and other styles
3

Tjärnlund, Anna. "Mucosal Immunity in Mycobacterial infections /." Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm university, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-6782.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Bailey, Jennifer Ruth. "Development of mucosal immunity in pigs." Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500402.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Smerud, Hilde Kloster. "IgA Nephropathy – Mucosal Immunity and Treatment Options." Doctoral thesis, Uppsala universitet, Institutionen för medicinska vetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-168631.

Full text
Abstract:
In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. The gluten sensitivity seemed to be an innate immune reaction unrelated to the pathogenesis of celiac disease. Approximately half of the patients had a rectal mucosal sensitivity to soy or cow’s milk (CM). The levels
APA, Harvard, Vancouver, ISO, and other styles
6

Alkazmi, Luay Mahmood M. A. "Mucosal immunity to the hookworm Ancylostoma ceylanicum." Thesis, University of Nottingham, 2004. http://eprints.nottingham.ac.uk/11876/.

Full text
Abstract:
The host-parasite relationship of the hookworm Ancylostoma ceylanicum was explored in a hamster model system, focusing on intestinal mucosal responses to infection. Primary infection induced a rapid reduction in villous height culminating in excess of 75% reduction by day 35. Crypts of Lieberkuhn increased in depth achieving maximum depth by day 35. Mitotic figures in crypts and mast cells increased until day 28. Goblet cells increased continuously from background levels of 50 cell/mm² to exceed 300 cells/mm² by day 42. Paneth cell numbers declined in infected animals. Termination of infection
APA, Harvard, Vancouver, ISO, and other styles
7

Philipson, Casandra Washington. "Systems analysis and characterization of mucosal immunity." Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/74392.

Full text
Abstract:
During acute and chronic infectious diseases hosts develop complex immune responses to cope with bacterial persistence. Depending on a variety of host and microbe factors, outcomes range from peaceful co-existence to detrimental disease. Mechanisms underlying immunity to bacterial stimuli span several spatiotemporal magnitudes and the summation of these hierarchical interactions plays a decisive role in pathogenic versus tolerogenic fate for the host. This dissertation integrates diverse data from immunoinformatics analyses, experimental validation and mathematical modeling to investigate a se
APA, Harvard, Vancouver, ISO, and other styles
8

Ye, Lilin. "FcRn mediated mucosal immunity and subunit vaccine delivery." College Park, Md.: University of Maryland, 2009. http://hdl.handle.net/1903/9815.

Full text
Abstract:
Thesis (Ph. D.) -- University of Maryland, College Park, 2009.<br>Thesis research directed by: Virginia-Maryland Regional College of Veterinary Medicine. Maryland Campus. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
APA, Harvard, Vancouver, ISO, and other styles
9

Barton, John Roger. "Human gastrointestinal mucosal secretory immunity : investigation and regulation." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/19960.

Full text
Abstract:
Current ideas of human gut immunity are derived heavily from animal studies; the few human studies have mainly addressed cellular aspects, and those on immunoglobulins and antibodies have used serum (or rarely jejunal aspirate) to investigate immune events at the gut level, assuming that these fluids are representative of the gut. The aims of this thesis were to develop, evaluate, and apply protocols for the study of gut secretions in man. Saliva was examined as a secretion in its own right, to investigate the relationship between systemic (serum) and mucosal antibodies, and as a potential mir
APA, Harvard, Vancouver, ISO, and other styles
10

Ewing, Patricia A., and n/a. "Developmental profiles of mucosal immunity in pre-school children." University of Canberra. Human & Biomedical Sciences, 2000. http://erl.canberra.edu.au./public/adt-AUC20060707.154930.

Full text
Abstract:
Previous studies of the ontogeny of the mucosal immune system have shown a significant increase in salivary Immunoglobulin A levels occurring at about five years of age. This study has monitored a group of 3 and 4 year old children during one year of attendance at Pre-School to examine whether such an increase could be linked to increased antigenic exposure associated with moving into a school like environment. Saliva samples were collected at regular intervals and analysed for immunoglobulin and total protein levels. Daily health records were maintained for each child, and a detailed social a
APA, Harvard, Vancouver, ISO, and other styles
11

Fowler, Sanna Margrethe. "The role of CD4'+ T cells in mucosal immunity." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393226.

Full text
APA, Harvard, Vancouver, ISO, and other styles
12

Croft, Nicholas Michael. "Investigation of gastrointestinal mucosal immunity and inflammation in children." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/21172.

Full text
Abstract:
In this thesis I have introduced a new technique, whole gut lavage (WGL), for the study of gastrointestinal secretory immunity in children. Initially I arranged to collect specimens from control children, undergoing whole gut lavage prior to colonoscopy or surgery, at the Royal Hospital for Sick Children, Edinburgh. Whole gut lavage has been used to treat severe constipation and so I organised a study to look at the effectiveness of this, intending both these groups of children as immunologically normal controls. Analysis of specimens from the first five severely constipated children showed th
APA, Harvard, Vancouver, ISO, and other styles
13

Brierley, Jennifer L. "Thermoregulation and mucosal immunity : the effects of environmental extremes." Thesis, Bangor University, 2013. https://research.bangor.ac.uk/portal/en/theses/thermoregulation-and-mucosal-immunity--the-effects-of-environmental-extremes(d5e98b6d-b1cf-45f7-8b99-bdf16b844c53).html.

Full text
Abstract:
The main objectives of this thesis were to: 1. investigate the effects of acute and chronic hypoxia on human thermoregulation and mucosal inununity, specifically salivary immunoglobulin A (s-IgA) and salivary alpha-amylase during mild cold exposure at rest (Chapter 4 and 5), 2. identify the effectiveness of four practical field re-warming methods for the field treatment of cold casualties on thennoregulation and metabolism (Chapter 6), 3. examine the s-IgA response during and following mild hypothennia (Chapter 7) and 4. detelmine the efficacy of three field protection methods for the preventi
APA, Harvard, Vancouver, ISO, and other styles
14

Biswal, Jitendra Kumar. "Evaluation of mucosal immunity in FMDV vaccinated and infected cattle." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572448.

Full text
APA, Harvard, Vancouver, ISO, and other styles
15

Vento, Kevin Leon. "Assessment of protective immunity following mucosal vaccination with Pseudomonas aeruginosa." Thesis, St George's, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408031.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

Tubau, Juni Nuria. "Characterization of Regulatory Mechanisms in Mucosal Immunity by Systems Immunology." Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/104250.

Full text
Abstract:
The mucosal immunity of the gastrointestinal (GI) tract is constituted by a complex, highly specialized and dynamic system of immune components that aim to protect the gut from external threats. The sustained exposure of the mucosal immune system of the GI tract to an enormous number of lumen antigens, requires the constant upkeep of a highly regulated balance between initiation of immune responses against harmful agents and the generation of immune tolerance towards innocuous antigens. Therefore, the regulatory component is key to preserve tissue homeostasis and a normal functioning of the sy
APA, Harvard, Vancouver, ISO, and other styles
17

McCluskie, Michael J. "Strategies for the induction of mucosal immunity against hepatitis B virus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0019/NQ45183.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Davidson, Giles Andrew. "Aspects of mucosal immunity in rainbow trout, Oncorhynchus mykiss (Walbaum. 1792)." Thesis, University of Aberdeen, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305007.

Full text
Abstract:
The immunological characteristics of the mucosae of rainbow trout, <i>Oncorhynchus mykiss</i>, were investigated. A technique for the isolation of viable cells from the intestinal and cutaneous mucosae was developed which enabled differential cell counts to be performed on suspensions of cells liberated from these sites. This was achieved using light and electron microscopical, enzyme histochemical and flow cytometric techniques. In cell suspensions derived from the intestinal mucosa, lymphocytes, macrophages and eosinophilic granulocytes (EGC) were present, lymphocytes being by far the most n
APA, Harvard, Vancouver, ISO, and other styles
19

Dahele, Anna V. M. "Systemic and gut mucosal immunity to tissue transglutaminase in coeliac disease." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/23318.

Full text
APA, Harvard, Vancouver, ISO, and other styles
20

Lundqvist, Carina. "Human intraepithelial lymphocytes a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa /." Umeå, Sweden : Dept. of Immunology, Umeå University, 1995. http://books.google.com/books?id=TKppAAAAMAAJ.

Full text
APA, Harvard, Vancouver, ISO, and other styles
21

West, Nicholas Peter. "Exercise, Immunity and Illness." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/367462.

Full text
Abstract:
Identifying immune biomarkers in healthy humans that indicate an increased susceptibility to upper respiratory tract illness (URTI) is necessary to develop improved diagnostic and treatment strategies. URTI is associated with substantial socio-economic and personal cost. Small to moderate reductions in the severity and duration of illness could lead to substantial reductions in these costs. This thesis investigated the relationship between the immune system and URTI in healthy individuals utilising exercise as a model of stress. Chapter 2 (Section 2.2) reviews the effects of exercise on the im
APA, Harvard, Vancouver, ISO, and other styles
22

Rouxel, Ophélie. "Rôles des cellules MAIT (Mucosal Associated Invariant T) dans la physiopathologie du diabète de type 1." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB114.

Full text
Abstract:
Le diabète de type 1 (DT1) est une maladie auto-immune caractérisée par la destruction sélective des cellules β pancréatiques entraînant une hyperglycémie et nécessitant un traitement par insulinothérapie à vie. La physiopathologie du DT1 est complexe et fait intervenir les cellules immunitaires innées et adaptatives dans la pathogenèse et la régulation du DT1. Alors que le développement du diabète peut être associé à des facteurs génétiques, des facteurs environnementaux sont également impliqués dans le déclenchement de cette maladie. Des études récentes ont mis en évidence le rôle du microbi
APA, Harvard, Vancouver, ISO, and other styles
23

Hu, Ke-Fei. "ISCOMs as delivery systems for mucosal immunization /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5417-4.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
24

Shirreff, Lisa M. "Characterization of an M. marinum Vaccine| Examination of Both Mucosal Immunity and Systemic Immunity in a Fish Model." Thesis, University of Louisiana at Lafayette, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10163372.

Full text
Abstract:
<p> <i>Mycobacterium marinum</i> (Mm) shares at least 80% amino acid sequence identity with over 3,000 orthologous genes of Mycobacterium tuberculosis (Mtb) and is thus used as a surrogate pathogen for Mtb research. Our laboratory investigates mycobacteriosis using Japanese medaka (<i> Oryzias latipes</i>) as an aquatic animal model. Mm disease presentation in medaka is similar to Mtb disease presentation in humans, including growth in macrophages, granulomatous lesions, and lifelong chronic disease. We have previously shown that a major route of infection in fish is through an oral route and
APA, Harvard, Vancouver, ISO, and other styles
25

Kay, R. A. "The mucosal regulation of the systemic immune response to cholera toxin." Thesis, University of Edinburgh, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380413.

Full text
APA, Harvard, Vancouver, ISO, and other styles
26

McDonald, John Leslie. "The Effects of Acupuncture on Mucosal Immunity in the Upper Respiratory Tract." Thesis, Griffith University, 2015. http://hdl.handle.net/10072/367594.

Full text
Abstract:
Allergic rhinitis is a common disease in Australia, with an estimated 3.17 million Australians affected. Allergic rhinitis represents a significant burden to the community in quality of life and wellbeing, impaired performance, loss of productivity and health care costs. A review was undertaken firstly of the research literature on the efficacy and effectiveness of acupuncture for allergic rhinitis, then secondly of the research into the mechanisms of acupuncture in allergic rhinitis. A total of 4 systematic reviews, 15 randomised controlled trials (RCTs) and other non- randomised studies on a
APA, Harvard, Vancouver, ISO, and other styles
27

SIDOTI, MIGLIORE GIACOMO. "Bacterial lysate enhances protective mucosal immunity via increased expression of antimicrobial peptides." Doctoral thesis, Università degli studi di Genova, 2021. http://hdl.handle.net/11567/1047077.

Full text
Abstract:
Polyvalent mechanical bacterial lysate (PMBL) has been reported to be effective in the prevention of common respiratory tract infections. PMBL are produced through a process that preserves the structure of the bacterial antigens and because of their immunogenic capabilities, increasing importance is given to its mechanism of action, not yet fully understood. Respiratory tract epithelial cells constitute a front-line physical barrier between the organism and the environment. They are able to sense pathogen associated molecular patterns and secrete a wide spectrum of protective factors. By using
APA, Harvard, Vancouver, ISO, and other styles
28

Darwish, Ammar. "Systemic and mucosal immunity in patients with periampullary cancer, obstructive jaundice and chronic pancreatitis." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/systemic-and-mucosal-immunity-in-patients-with-periampullary-cancer-obstructive-jaundice-and-chronic-pancreatitis(b6e3ee83-3e4e-4b34-8c36-8eb75c3961cc).html.

Full text
Abstract:
Introduction: Derangement of systemic and mucosal immunity, which are the integral components of the immune system, increases the risk of septic complications in patients postoperatively. The aims of this study were to investigate the integrity of systemic immunity as well as the mucosal immune system in patients with pancreatic cancer (PC), chronic pancreatitis (CP) and obstructive jaundice (OJ).Method: Healthy controls, as well as four groups of patients were studied. These included; jaundiced patients with PC, jaundiced patients secondary to benign disease (choledocholithiasis), non-jaundic
APA, Harvard, Vancouver, ISO, and other styles
29

Jackson, Courtney M. "Chorioamnionitis induces systemic and mucosal immune responses in the developing fetus." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592818915104982.

Full text
APA, Harvard, Vancouver, ISO, and other styles
30

Hou, Lin. "The distribution and characterization of protease-activated receptors in oral mucosa and skin." Thesis, Queen Mary, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286544.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

SPOSITO, BENEDETTA. "Type III Interferons: Running Interference with Mucosal Repair." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2023. https://hdl.handle.net/10281/402377.

Full text
Abstract:
Gli interferoni (IFN) sono mediatori e regolatori fondamentali della risposta immunitaria dell'ospite a virus e ad altri agenti microbici. Gli IFN di tipo I e di tipo III (o IFN-λ) sono tra le prime citochine ad essere indotte in seguito a infezioni virali. Il legame tra gli IFN e i rispettivi recettori attiva vie di trasduzione del segnale simili tra loro che inducono l'espressione di geni stimolati dagli IFN (ISG) con funzioni antivirali. La caratteristica principale che rende ciascuna di queste famiglie di IFN unica e non ridondante è l'esistenza di recettori distinti che fanno sì che gli I
APA, Harvard, Vancouver, ISO, and other styles
32

Da, Silva Clément. "Fonction des phagocytes de la plaque de Peyer dans la réponse immunitaire mucosale." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0251.

Full text
Abstract:
Nous avons mis en évidence la présence des phagocytes exprimant le lysozyme dans les Plaque de Peyer chez l’Homme et montré que, comme chez la souris, elles sont principalement localisées dans le SED et sont distinctes des cDC. Dans un deuxième temps, nous avons étudié dans les PP de souris la fonction des différentes populations de phagocytes nouvellement caractérisées. Nous avons en particulier étudié l’impact de la détection d’un acide nucléique d’origine virale par les phagocytes en utilisant un agoniste synthétique du TLR7 : le R848. Bien que TLR7 soit exprimé par les cellules dérivées de
APA, Harvard, Vancouver, ISO, and other styles
33

Gold, Matthew Joshua. "Role of group 2 innate lymphoid cells and SHIP-1 in mucosal immunity." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/51891.

Full text
Abstract:
Mucosal surfaces present an important barrier between the host and environment. Maintenance of barrier function requires intricate cross-talk between a diverse array of immune cells and the epithelia, acting synergistically to respond to harmful antigens and maintain tolerance to innocuous antigens. In this thesis I utilized an array of transgenic animals to explore the cellular and molecular mechanisms that initiate adaptive immune responses in the lung and gut mucosa. Recently, innate lymphoid cells have been characterized for their role in maintaining barrier immunity. Group 2 innate lym
APA, Harvard, Vancouver, ISO, and other styles
34

Mills, Jamie-Lee S. "Modelling natural immunity to streptococcal mucosal infections and novel approaches to vaccine delivery." Thesis, Griffith University, 2022. http://hdl.handle.net/10072/414917.

Full text
Abstract:
Streptococcus pyogenes causes significant global morbidity and mortally through a range of pathologies. The most common sites of infection are the upper respiratory tract and the skin, resulting in pharyngitis and impetigo respectively. Non-invasive infections are usually self-limiting; however, they have the potential to progress to life threatening invasive diseases such as toxic-shock syndrome and necrotizing fasciitis with a high rate of mortality. Furthermore, S. pyogenes infections can give rise to auto-immune sequelae of ARF/RHD and ASPGN that result in approximately 500 000 deaths each
APA, Harvard, Vancouver, ISO, and other styles
35

Ruberti, Maristela 1975. "Caracterização fenotípica e funcional das células imunocompetentes da mucosa intestinal envolvidas na tolerância oral a ovalbumina." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317404.

Full text
Abstract:
Orientador: Wirla Maria da Silva Cunha Tamashiro<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-20T10:43:40Z (GMT). No. of bitstreams: 1 Ruberti_Maristela_D.pdf: 10774061 bytes, checksum: 7afe7ee8aa8c7f97c1f80e66f0cd8bfa (MD5) Previous issue date: 2012<br>Resumo: Trabalhos anteriores de nosso laboratório mostraram que camundongos transgênicos DO11.10, cuja maioria dos linfócitos T expressam TCR específico para ovalbumina (OVA) no contexto de...Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da
APA, Harvard, Vancouver, ISO, and other styles
36

Permpoonpattana, Patima. "Clostridium difficile : infection and immunity." Thesis, Royal Holloway, University of London, 2013. http://repository.royalholloway.ac.uk/items/33009ec4-7815-0803-d39b-f968c8d9cdbb/7/.

Full text
Abstract:
Clostridium difficile is a Gram positive pathogen of significant importance in the UK, Europe and the USA. No vaccine has been developed and current treatments are focused on hospital management and the use of antibiotics. The disease is spread in hospitals in the spore form and the role of spores in C. difficile infecton is poorly understood. In this project spores of C. difficile have been characterised. The proteins from the outermost layers of the spore were identified and the genes cloned. Three of these surface proteins have unique enzymatic properties that maybe important for symptoms o
APA, Harvard, Vancouver, ISO, and other styles
37

Martin, Tara L. "The STING Ligand 3’3’-cGAMP Effectively Elicits Mucosal and Systemic Immunity Following Sublingual Immunization." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461331044.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Rodríguez, Ariane. "Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-388.

Full text
Abstract:
<p>The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases.</p><p>One of the pathogens infecting the host via the respiratory tract is <i>Mycobacterium Tuberculosis</i>. The reported efficacy of the currently used Bacillus Calmette-Guérin (BCG) vaccine against tuberculosis is highly variable, ranging from 50% against pulmonary tuberculosis to 80% against disseminated tuberculosis. Recently, the curren
APA, Harvard, Vancouver, ISO, and other styles
39

Rodrʹiguez, Muñoz Ariane. "Mucosal immunity in the respiratory tract : the role of IgA in protection against intracellular pathogens /." Stockholm : Dept. of Immunology, The Wenner-Gren Institute, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-388.

Full text
APA, Harvard, Vancouver, ISO, and other styles
40

Morris, Bruce C. "Intestinal Mucosal Mast Cell Immune Response and Pathogenesis of Two Eimeria Acervulina Isolates in Broiler Chickens." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/36228.

Full text
Abstract:
Five experiments were conducted comparing differential intestinal immune responses to two isolates of Eimeria acervulina (EA), EA1 and EA2. In three experiments, broiler chicks were divided into control (non-challenged), EA1, or EA2 challenged (14 days of age) groups. On day 6 post-challenge (PC), changes in body weight were determined, intestinal lesions were scored, and duodenal tissue was evaluated for morphometric alterations and mucosal mast cell responses. EA1 produced duodenal lesions and reduced villus height to crypt depth ratios when compared to controls; however, no differences we
APA, Harvard, Vancouver, ISO, and other styles
41

Srinivasan, N. "The role of inflammasomes in intestinal inflammation." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:04ad577c-a8dd-46eb-811a-79a3980ff806.

Full text
Abstract:
Single Nucleotide Polymorphisms (SNPs) in the intracellular pattern recognition receptor gene NLRP3 are associated with susceptibility to Crohn’s disease, a form of inflammatory bowel disease (IBD). Following cell damage or infection, NLRP3 triggers the formation of inflammasomes, a multimolecular protein complex containing NLRP3, ASC and caspase-1, which mediate secretion of IL-1β and IL-18. NLRP3 inflammasome activation in macrophages has been implicated in protection against several pathogens, but whether NLRP3 activation in tissue cells contributes to protective immunity against bacterial
APA, Harvard, Vancouver, ISO, and other styles
42

Ambrose, Zandrea. "Immune control of SHIV in macaques upon mucosal infection of immunization /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9290.

Full text
APA, Harvard, Vancouver, ISO, and other styles
43

Junior, Andrés Jimenez Galisteo. "Toxoplasma gondii vs radiação ionizante: imunidade humoral e celular em baço e intestino de camundongos isogênicos imunizados com taquizoítos irradiados por Cobalto 60." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-17082009-173434/.

Full text
Abstract:
Toxoplasma gondii vs radiação ionizante: Imunidade humoral e celular em baço e intestino de camundongos isogênicos imunizados com taquizoítos irradiados por Cobalto 60 Andrés Jimenez Galisteo Jr. Estudamos o desenvolvimento de uma vacina para toxoplasmose utilizando a radiação ionizante como ferramenta. Aqui avaliamos o desenvolvimento da imunidade sistêmica e intestinal e a resistência à infecção, em diferentes camundongos imunizados, por via oral e parenteral, com taquizoítos irradiados a 255 Gy e desafiados com cistos da cepa ME49. Camundongos C57Bl/6j, BALB/c e C57Bl/6j IFN--/- foram imuni
APA, Harvard, Vancouver, ISO, and other styles
44

Clever, David C. Clever. "T Cell-Intrinsic PHD Proteins Regulate Pulmonary Immunity." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1471868519.

Full text
APA, Harvard, Vancouver, ISO, and other styles
45

Liang, Bin. "Characterisation of the mucosal immunity in the nasal-associated lymphoid tissue following influenza A virus infection." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271049.

Full text
APA, Harvard, Vancouver, ISO, and other styles
46

Ohue, Ryuji. "Studies on the regulatory responses of mucosal immunity to the environmental changes in the gastrointestinal tract." Kyoto University, 2012. http://hdl.handle.net/2433/157716.

Full text
Abstract:
Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第16925号<br>農博第1941号<br>新制||農||1001(附属図書館)<br>学位論文||H24||N4686(農学部図書室)<br>29600<br>京都大学大学院農学研究科食品生物科学専攻<br>(主査)教授 谷 史人, 教授 伏木 亨, 教授 井上 國世<br>学位規則第4条第1項該当
APA, Harvard, Vancouver, ISO, and other styles
47

Stoicov, Calin. "Pathogenesis of the Helicobacter Induced Mucosal Disease: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/477.

Full text
Abstract:
Helicobacter pylori causes chronic gastritis, peptic ulceration and gastric cancer. This bacterium is one of the most prevalent in the world, but affects mostly the populations with a lower socioeconomical status. While it causes gastric and duodenal ulcers in only 20% of infected patients, less then 1% will develop gastric adenocarcinoma. In fact, H. pylori is the most important risk factor in developing gastric cancer. Epidemiological studies have shown that 80% of gastric cancer patients are H. pylori positive. The outcome of the infection with this bacterium depends on bacterial factors, d
APA, Harvard, Vancouver, ISO, and other styles
48

Nosralla, Liara Nogueira Petrechen. "Níveis e complexidade de IgA contra estreptococos orais em amostra de colostro humano." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17144/tde-29032017-165520/.

Full text
Abstract:
Após o nascimento, os recém-nascidos são expostos a vários tipos de micro-organismos, que podem determinar um processo infeccioso devido a sua imaturidade imunológica. Dentro deste processo, a amamentação tem um papel importante pela transferência passiva de imunoglobulina A (IgA). A cavidade oral é a principal porta de entrada destes agentes, especialmente os estreptococos, sendo que alguns colonizam inicialmente como Streptococcus gordonii (SGO), S. sanguinis (SSA) e S. mitis (SMI) e outros podem causar doenças, como S. mutans (SM), por ser o principal agente etiológico da cárie dentária. Po
APA, Harvard, Vancouver, ISO, and other styles
49

O’Meara, Connor Patrick. "The development of an effective vaccine against Chlamydia : utilisation of a non-toxic mucosal adjuvant to generate a protective mucosal response." Thesis, Queensland University of Technology, 2012. https://eprints.qut.edu.au/61614/1/Connor_O%27Meara_Thesis.pdf.

Full text
Abstract:
Chlamydia is responsible for a wide range of diseases with enormous global economic and health burden. As the majority of chlamydial infections are asymptomatic, a vaccine has greatest potential to reduce infection and disease prevalence. Protective immunity against Chlamydia requires the induction of a mucosal immune response, ideally, at the multiple sites in the body where an infection can be established. Mucosal immunity is most effectively stimulated by targeting vaccination to the epithelium, which is best accomplished by direct vaccine application to mucosal surfaces rather than by inje
APA, Harvard, Vancouver, ISO, and other styles
50

Bonnardel, Johnny. "Caractérisation phénotypique, ontogénique et fonctionnelle du système phagocytaire mononucléé des plaques de Peyer." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4048.

Full text
Abstract:
Les plaques de Peyer (PP) sont les principaux sites inducteurs de la réponse immunitaire mucosale.L’épithélium associé aux follicules comprend des cellules épithéliales spécifiques, appelées cellules M et spécialisées dans le transport du matériel présent dans la lumière intestinale vers le dôme sous épithélial (SED) où il sera pris en charge par les cellules du système phagocytaire mononuclée (MPS) qui orchestreront ensuite les réponses immunitaires mucosales.Nous avons effectué une analyse complète du phénotype, de la distribution, de l’ontogénie, de la fonction et des profils transcriptomiq
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'Mucosal immunity' for other source types:
Journal articles Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography