Academic literature on the topic 'Mucous membrane – Cancer'

Jaundice, also known as icterus, is the yellowish discolouration seen in skin, mucous membranes, and sclerae when the plasma bilirubin concentration is >40 μ‎mol/l. Jaundice may arise from increased production of bilirubin, for instance, in haemolysis; from reduced conjugation in the liver, as in Gilbert’s syndrome; or from reduced excretion via bile, as in intra-hepatic cholestasis. Jaundice also occurs when the flow of bile is obstructed, for instance, by gallstones or pancreatic cancer (extra-hepatic cholestasis). The clinical approach to the jaundiced patient is described in this topic.

Melanoma is a cancer of melanocytes, cells that produce the brown-black skin pigment melanin. Melanocytes originate in cells of the neural crest and migrate during embryogenesis, principally to the epidermis, eyes, and some mucous membranes (mouth, nose, esophagus, anus, genitourinary organs, and conjunctiva). Cutaneous melanoma afflicts mainly fair-skinned people of European origin, among whom sun exposure is the major cause. Five-year relative survival can exceed 90%. Invasive cutaneous melanoma in US whites occurs mostly on the trunk (34%), and upper limbs and shoulders (26%). Melanoma inci

Dermatology is the study of the skin, hair, nails, and oral and genital mucus membranes and the diseases affecting them. It is predominantly an outpatient specialty. This chapter explains the common terminology used to describe skin lesions and dermatoses. The commonest conditions encountered in the dermatology clinic are described: eczema, psoriasis, pyoderma gangrenosum, skin cancers (basal cell skin cancer, squamous cell skin cancer, malignant melanoma), acne vulgaris and bullous disorders, in addition to dermatological manifestations of systemic disease such as vasculitis. Emergency presentations such as Stevens–Johnson syndrome/toxic epidermal necrolysis, anaphylaxis, and necrotizing fasciitis are outlined. A practical guide to common dermatological procedures such as punch biopsy, and a clinical approach to the dermatological patient are included.

Endemic arsenocosis (chronic arsenic poisoning) in China comes from two sources of arsenic (As). One source is drinking water, with As concentrations 2-40 times that of the state standard of 0.05 mg/l As. The second is smoke pollution from combustion of coal with high concentrations of As; this can be inhaled or ingested from smoke-contaminated food. Over 2,000,000 people live in areas of high geological As concentrations (Cao 1996), and more than 17,000 arsenocosis patients in 21 counties of five provinces or Autonomous Regions have been identified. Long-term exposure to As in air, diet, or drinking water can result in permanent and severe damage to health, including lesions of the skin, mucous membranes of the digestive, respiratory, circulatory, and nervous systems, and rhagades (skin cleft on palm and feet). Elevated As intake is also associated with skin, liver, and lung cancers (Centeno 2000, Liang 1999, Wang Lianfang 54-61 1997). At present, there are few studies of efficient measurement of treatment of endemic arsenocosis patients. Our study demonstrates that treatment of these patients with dietary selenium (Se) can cause both excretion (elimination) of As accumulated in the human body and remediation of some health damages. We report the results of this experiment. Data were collected on 3 test groups of people: 186 patients, from BaYinMaoDao Farm in Inner Mongolia suffering from endemic arsenocosis, were divided into a treatment group (100 patients) and a control group (86 patients). A third group, consisting of 70 families, received no treatment but drank ambient well water, >0.10 mg/l As. All participants had been exposed to high-As drinking water (>0.10 mg/l) since 1983. Throughout the experiment, water containing 0.05 mg/1 As was supplied for both treatment and control groups. Of the 186 patients, 100 were treated with Se-enriched yeast tablets, containing 100 μg Se/tablet. The treatment lasted 14 months. Treated patients received 100-200 μg Se/day. All patients were examined for clinical criteria of arsenocosis: characteristic pigmentation, depigmentation, hyperkeratosis, rhagades (skin cleft), and incidence of secondary symptoms of headaches, dizziness, thoracalgia (chest pain), numbness of hands or feet, convulsions, or lumbago.

HPV - short for human papillomavirus - is a virus capable of infecting the mucous membranes and skin, being the most prevalent involved on Sexually Transmitted Diseases and the main cause of Cervical Cancer. However, reaching out to and inviting all eligible people for cervical cancer screening and vaccination against HPV is a difficult task. A possible solution is the use of social inducement and gamification through modern means of communication, which may encourage the attendance of unscreened or unvaccinated people on related programs. Therefore, this paper presents the development of a se