Log in

Relevant bibliographies by topics / Mucous Membrane, drug effects

Contents

Journal articles
Dissertations / Theses
Books
Book chapters
Conference papers
Reports

Academic literature on the topic 'Mucous Membrane, drug effects'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Mucous Membrane, drug effects.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Mucous Membrane, drug effects"

1

Kotsyumbas, I. Ya, I. P. Patereha, V. I. Kushnir, S. Yа Martynyk, M. I. Zhyla, and М. М. Chudyak. "SETTING OF PARAMETERS OF ACUTE AND SUBACUTE TOXICITY OF THE POWDER BASED ON IODOFORM." Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 22, no. 1 (2021): 103–9. http://dx.doi.org/10.36359/scivp.2021-22-1.11.

Full text

Abstract:

The article presents the results of establishing the parameters of acute and subacute toxicity of the powder based on iodoform. Determination of acute toxicity parameters of the drug "Iodomin" were performed on 30 white mice 2-3 months of age, weighing 20-23 g and 30 white rats, aged 2-3 months, weighing 170-190 g. The drug was administered intragastrically, once, pre-dissolved in water. As a result of studies to determine acute toxicity by oral administration, it was found that, after administration of the drug in doses of 1000, 3000 and 5000 mg/kg, all animals remained alive. No change

APA, Harvard, Vancouver, ISO, and other styles

2

Vorobyeva, Natalya M., Irina P. Malaya, Vadim D. Zakiev, and Olga N. Tkacheva. "The possibility of using gastroenteroprotector rebamipide to improve the antithrombotic therapy safety." Clinical review for general practice 4, no. 6 (2023): 51–56. http://dx.doi.org/10.47407/kr2023.4.5.00271.

Full text

Abstract:

Antithrombotic drugs (antiplatelet agents and anticoagulants) are widely used in cardiological practice for primary and secondary prevention of thrombotic/thromboembolic complications, however, the use of such drugs is associated with the increased risk of hemorrhagic complications, including gastrointestinal hemorrhage. Assessment by video capsule endoscopy has shown that the damaging effects of antithrombotic drugs are not confined to the upper gastrointestinal mucosa, but also expand to the lower gastrointestinal tract, affecting small and large intestine. That is why it is reasonable to us

APA, Harvard, Vancouver, ISO, and other styles

3

Podolyuk, M. V., L. R. Mateshuk-Vatseba, M. M. Mykhalevych, V. B. Fik, and I. P. Pasichnyuk. "SCANNING ELECTRONIC MICROSCOPY OF MUCOUS MEMBRANE OF THE UTERINE TUBE UNDER THE CONDITIONS OF PHYSIOLOGICAL NORM AND SIX-WEEK ADMINISTRATION OF OPIOID." Art of Medicine 23, no. 3 (2022): 94–98. http://dx.doi.org/10.21802/artm.2022.3.23.94.

Full text

Abstract:

The toxic effects of opioids on the female reproductive system are important for theoretical and practical medicine, because excessive use of narcotic drugs causes pathological changes in organs and tissues and can predict the negative effects of "nalbuphine" on the female genitals. The excessive use of narcotic drugs, the prevalence of drug addiction, the use of opioids by modern medicine for therapeutic purposes, creates the need to carefully study the effects of opioids on the body of women, primarily the organs of the reproductive system, because despite the successes achieved in diagnosis

APA, Harvard, Vancouver, ISO, and other styles

4

Carvalho, Flávia Chiva, Marcos Luciano Bruschi, Raul Cesar Evangelista, and Maria Palmira Daflon Gremião. "Mucoadhesive drug delivery systems." Brazilian Journal of Pharmaceutical Sciences 46, no. 1 (2010): 1–17. http://dx.doi.org/10.1590/s1984-82502010000100002.

Full text

Abstract:

Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase and both local and systemic effects. Mucoadhesion is currently explained by six theories: electronic, adsorption, wettability, diffusion, fracture and mechanical. Several in vitro and in vivo methodologies are proposed for studying its mechanisms. However, mucoadhesion is not yet well understood. The aim of this study was to review

APA, Harvard, Vancouver, ISO, and other styles

5

Golubeva, M. I., М. V. Bidevkina, I. A. Bobrineva, et al. "EXPERIMENTAL STUDY OF THE TOXICITY AND HAZARD OF QUETIAPINE FUMARATE." Toxicological Review, no. 6 (January 5, 2021): 54–58. http://dx.doi.org/10.36946/0869-7922-2020-6-54-58.

Full text

Abstract:

Quetiapine is a psychotropic drug, a dibenzothiazepine derivative and a representative of the class of neuroleptics (antipsychotic drugs) of a new subgroup – atypical antipsychotic drugs («second-generation antipsychotics»). Quetiapine fumarate belongs to the 3rd hazard class in terms of DL50 when administered in the stomach according to GOST 12.1.007-76 (DL50 1380-1680 mg/kg, mice and rats), has a local irritant effect: pronounced - on the mucous membrane of the eyes and moderately pronounced - on the skin. There are no signs of skin resorptive or cumulative effects of quetiapine fumarate. Wh

APA, Harvard, Vancouver, ISO, and other styles

6

Het, Patel*, Patel Jaini, Ghanshyam Patel Dr., Yadav Priyanka, and Divykant Patel Dr. "REVIEW-SUBLINGUAL ROUTE FOR SYSTEMIC DRUG DELIVERY." World Journal of Pharmaceutical Science and Research 2, no. 2 (2023): 45–57. https://doi.org/10.5281/zenodo.10894235.

Full text

Abstract:

Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual literally meaning is “under the tongue”, administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in ger

APA, Harvard, Vancouver, ISO, and other styles

7

Kiryanova, V. V., V. A. Alexandrova, and A. V. Gordeichuk. "NARROWBAND OPTICAL EMISSION WAVELENGTH OF 540 NMIN THE COMPLEX TREATMENT OF CHILDREN WITH CHRONIC GASTRODUODENITIS." HERALD of North-Western State Medical University named after I.I. Mechnikov 9, no. 1 (2017): 102–6. http://dx.doi.org/10.17816/mechnikov201791102-106.

Full text

Abstract:

Effects of low-intensity narrow-band optical irradiation wavelength of 540 nm on the clinical course of chronic gastroduodenitis in children, the mucous membrane of upper gastrointestinal tract morpho- logical status, the motor function of the gallbladder and esophagus. It was discovered that combina- tion therapy has a definite advantage over drug treatment on elimination of clinical manifestations and morphological and motor indicators of gastrointestinal tract dicfunction

APA, Harvard, Vancouver, ISO, and other styles

8

Mykhalevych Marta, Paltov Yevgen та Kryvko Yurii. "ПАТОМОРФОЛОГІЧНІ ЗМІНИ СТРУКТУР ПІДНИЖНЬОЩЕЛЕПНОЇ СЛИННОЇ ЗАЛОЗИ НАПРИКІНЦІ 6-го ТИЖНЯ ЕКСПЕРИМЕТАЛЬНОГО ОПІОЇДНОГО ВПЛИВУ". Science Review, № 3(30) (31 березня 2020): 3–6. http://dx.doi.org/10.31435/rsglobal_sr/31032020/6992.

Full text

Abstract:

    The significant using of drugs and the prevalence of drug addiction in the last decades necessitates the study of the effects of opioids on the structural organization of organs and systems. The people with drug addiction syndrome have functional disorders of the salivary glands earlier than morphological changes in the mucous membrane of oral cavity.Reducing the amount of saliva and changing its composition lead to negative changes in the oral barrier function, salivary pH which is the main natural regulator of oral cavity homeostasis. This publication demonstrates

APA, Harvard, Vancouver, ISO, and other styles

9

Pawar, Poonam P., Hemant S. Ghorpade, and Bhavana A. Kokane. "Sublingual route for systemic drug delivery." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 340–43. http://dx.doi.org/10.22270/jddt.v8i6-s.2097.

Full text

Abstract:

Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual literally meaning is “under the tongue”, administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in geriatric, pedi

APA, Harvard, Vancouver, ISO, and other styles

10

Kishimoto, Hisanao, Caroline Ridley, Katsuhisa Inoue, and David J. Thornton. "Assessment of polymeric mucin–drug interactions." PLOS ONE 19, no. 6 (2024): e0306058. http://dx.doi.org/10.1371/journal.pone.0306058.

Full text

Abstract:

Mucosal-delivered drugs have to pass through the mucus layer before absorption through the epithelial cell membrane. Although there has been increasing interest in polymeric mucins, a major structural component of mucus, potentially acting as important physiological regulators of mucosal drug absorption, there are no reports that have systematically evaluated the interaction between mucins and drugs. In this study, we assessed the potential interaction between human polymeric mucins (MUC2, MUC5B, and MUC5AC) and various drugs with different chemical profiles by simple centrifugal method and fl

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Mucous Membrane, drug effects"

1

Sajadi, Tabassi Sayyed Abolghasem. "Some effects of mercaptans on membranes and mucus." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243647.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Yip, Aaron. "Effects of Angelica sinensis extract on mucus synthesis and cell proliferation of the stomach." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22227234.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Paulsson, Mattias. "Controlled Release Gel Formulations for Mucosal Drug Delivery." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5173-X/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

葉衍葳 and Aaron Yip. "Effects of Angelica sinensis extract on mucus synthesis and cell proliferation of the stomach." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31969884.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Julian, Thomas Nicholas. "The Effects of ultrasound on drug permeation through membrane barriers /." Ann Arbor, Mich. : Univ. Microfilms Intern, 1985. http://www.gbv.de/dms/bs/toc/016438418.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Mathers, Alicia R. "The effects of the route of viral infection on the balance of T helper immune responses." Morgantown, W. Va. : [West Virginia University Libraries], 2005. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=3825.

Full text

Abstract:

Thesis (Ph. D.)--West Virginia University, 2005<br>Title from document title page. Document formatted into pages; contains ix, 155 p. : ill. Vita. Includes abstract. Includes bibliographical references.

APA, Harvard, Vancouver, ISO, and other styles

7

Ziegler, Hanne Lindvig. "Antiplasmodial activity of natural products : effect of incorporation into erythrocyte membrane /." Cph. : Royal Danish School of Pharmacy, Department of Medicinal Chemistry, 2002. http://www.dfh.dk/phd/defences/hanneziegler.htm.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Dricu, Anica. "Role of dolichyl phosphate, N-linked glycosylation and cell membrane expression of insulin-like growth factor-1 receptor in maintenance of malignant cell growth /." Stockholm, 1997. http://diss.kib.ki.se/1997/91-628-2751-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Engvall, Caroline. "Drug Partitioning into Natural and Artificial Membranes : Data Applicable in Predictions of Drug Absorption." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5752.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

FRANCA, CYNTHIA M. "Avaliação in vivo dos efeitos preventivo e terapeutico do laser em baixa intensidade em mucosite bucal induzida por quimioterápico em hamsters." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11390.

Full text

Abstract:

Made available in DSpace on 2014-10-09T12:51:25Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T13:56:25Z (GMT). No. of bitstreams: 1 11303.pdf: 21897794 bytes, checksum: dd08773f11bb9dc32569446f5352b1cf (MD5)<br>Dissertacao (Mestrado Profissionalizante em Lasers em Odontologia)<br>IPEN/D-MPLO<br>Intituto de Pesquisas Energeticas e Nucleares, IPEN/CNEN-SP; Faculdade de Odontologia, Universidade de Sao Paulo

APA, Harvard, Vancouver, ISO, and other styles

More sources

Books on the topic "Mucous Membrane, drug effects"

1

Farage, Miranda A., Christian Surber, and Peter Elsner. Topical applications and the mucosa. Karger, 2011.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

2

Mucke, Hermann A. M. Transdermal & transmucosal therapeutics: New developments in drug delivery. D & MD Publications, 2004.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

3

Khutoryanskiy, Vitaliy V. Mucoadhesive materials and drug delivery systems. John Wiley & Sons, Inc., 2014.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

4

Filaretova, L. P. (Li︠u︡dmila Pavlovna) and Takeuchi K. (Koji), eds. Cell/tissue injury and cytoprotection/organoprotection in the gastrointestinal tract: Mechanisms, prevention, and treatment. Karger, 2012.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

5

C, Aloia Roland, Curtain Cyril C, and Gordon Larry M, eds. Drug and anesthetic effects on membrane structure and function. Wiley-Liss, 1991.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

6

-P, Kraehenbuhl J., and Neutra M. R, eds. Defense of mucosal surfaces: Pathogenesis, immunity and vaccines. Springer, 1999.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

7

Robert, Lu D., and Øie Svein, eds. Cellular drug delivery: Principles and practice. Humana Press, 2004.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

8

K, Majumder Hemanta, ed. Drug targets in kinetoplastid parasites. Springer Science+Business Media, 2008.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

9

C, Srivastava R. Surface activity in drug action. Elsevier, 2005.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

10

Yuan, Jason X.-J., 1963- and Ward Jeremy P. T, eds. Membrane receptors, channels, and transporters in pulmonary circulation. Springer, 2010.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Book chapters on the topic "Mucous Membrane, drug effects"

1

Vincenzi, F. F., and T. R. Hinds. "Drug Effects on Plasma Membrane Calcium Transport." In Calcium in Drug Actions. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-71806-9_8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Mason, R. Preston. "Molecular mechanisms underlying the effects of cholesterol on neuronal cell membrane function and drug-membrane interactions." In Lipids, health, and behavior. American Psychological Association, 1997. http://dx.doi.org/10.1037/10259-007.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Lúcio, Marlene, José L. F. C. Lima, and Salette Reis. "Drug-Membrane Interactions: Molecular Mechanisms Underlying Therapeutic and Toxic Effects of Drugs." In Ideas in Chemistry and Molecular Sciences. Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527630516.ch8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Rana, Prof (Dr ). Yesh Partap Singh, and Mr Syed Basharat Bukhari. "TOPICAL PREPARATIONS: OINTMENTS, CREAMS, PASTES, GELS, LINIMENTS AND LOTIONS, SUPPOSITORIES AND PESSARIES." In PRELIMINARY PHARMACEUTICS. KAAV PUBLICATIONS, 2023. http://dx.doi.org/10.52458/9788196830045.2023.eb.ch-15.

Full text

Abstract:

Topical preparations, crucial for localized or systemic effects, encompass diverse formulations applied to skin, mucous membranes, or body cavities. This chapter delves into ointments, creams, pastes, gels, liniments and lotions, and suppositories and pessaries. Ointments, semisolid with water-free bases, offer localized treatment, though may be greasy. Creams, versatile emulsions, provide ease of spread ability but offer shorter occlusivity. Pastes, with concentrated powdered solids, serve protective purposes. Gels, semi-solid and transparent, ensure rapid drug release and soothing effects. L

APA, Harvard, Vancouver, ISO, and other styles

5

Dhondibhau, Ghangale Gauri. "Topical Preparations." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/t4gjs095.

Full text

Abstract:

Topical preparations are dosage forms designed for application to the skin or mucous membranes, offering localized drug delivery and systemic effects in some cases. This section covers various types of topical formulations, including creams, ointments, gels, and transdermal patches. The structure and barrier properties of the skin are discussed in relation to drug penetration and absorption. Formulation considerations for topical preparations, such as drug solubility, partition coefficient, and vehicle selection, are explored to optimize drug delivery. The role of penetration enhancers and the

APA, Harvard, Vancouver, ISO, and other styles

6

Adeola, Henry A., Rashmi Bhardwaj, Aderonke F. Ajayi-Smith, et al. "Bioactive Compounds as Therapeutic Intervention in Mucocutaneous Cancers." In Therapeutic Use of Plant Secondary Metabolites. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815050622122010008.

Full text

Abstract:

There are several beneficial effects of plant bioactive compounds in theevidence-based prevention and treatment of mucocutaneous cancers. For instance,several bioactive compounds via various antioxidant and immunomodulatorymechanisms have been shown to positively improve different diseases, includingcancer. Considering the complex, multifactorial processes that regulate genetic andcellular function in cancer development, the use of small phytochemical moleculescapable of targeting multiple carcinogenetic genes and pathways is plausible. Furthermore, the identification of molecular targets and

APA, Harvard, Vancouver, ISO, and other styles

7

Goel, Ms Neha. "Dosage Forms." In Edited Book of Pharmaceutics – I [According to Latest Syllabus of B. Pharm-I Semester of Pharmacy Council of India]. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurepch3.

Full text

Abstract:

Dosage forms are the means by which drug molecules are delivered to sites of action within the body. They are essential for ensuring the safe, effective, and controlled delivery of medication to achieve the desired therapeutic effect. The introduction to dosage forms encompasses a wide range of formulations designed to meet various medical needs and patient preferences. Dosage forms are broadly classified based on their physical state and route of administration. The primary classifications include solid, liquid, and semi-solid forms. Solid dosage forms include tablets, capsules, powders, and

APA, Harvard, Vancouver, ISO, and other styles

8

Fuchs, Ju¨rgen. "Environmental Effects on Skin Lipids and Impairment of Barrier Function." In Membrane Structure in Disease and Drug Therapy. CRC Press, 2000. http://dx.doi.org/10.1201/9780203910054.ch5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Kadenbach, Bernhard, and Susanne Arnold. "3,5-Diiodothyronine Binds to Subunit Va of Cytochrome c Oxidase Possible Mechanism of Short-Term Effects of Thyro." In Membrane Structure in Disease and Drug Therapy. CRC Press, 2000. http://dx.doi.org/10.1201/9780203910054.ch15.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Gavhane, Snehal A., and Sachin B. Somwanshi. "PRODRUG: APPROACH TO BETTER DRUG DELIVERY." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 8. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn8p1ch8.

Full text

Abstract:

Albert was the first to introduce the idea of a prodrug in medicinal chemistry. "A prodrug is a molecule that lacks intrinsic biological activity but can produce a biologically active drug through the various stages of its metabolism," according to the definition provided. This definition and the one adopted by IUPAC both state that a prodrug is any substance that goes through biotransformation prior to manifesting its pharmacological effects. Prodrugs can be thought of as medications that temporarily alter or remove undesired qualities in the parent molecule by adding specialised non-toxic pr

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Mucous Membrane, drug effects"

1

"Analogue of glucagon-like peptide-1 - properties, mechanisms of action, prospects for use." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-8-39-44.

Full text

Abstract:

Glucagon-like peptide-1 is an isulin-like peptide hormone from the incretin family. It is secreted by L-cells of the mucous membrane of the ileum and colon, enhances insulin secretion and is a physiological regulator of appetite. The most popular pharmaceutical analogue of GLP-1 at the moment is liraglutide. Liraglutide also activates GLP-1 receptors, but is more stable and allows you to get a more powerful effect due to the prolongation of the drug. It is known that the action of liraglutide extends to all tissues with GLP-1 receptors, but now the drug is used only for correction of body weig

APA, Harvard, Vancouver, ISO, and other styles

2

Veshchemova, T. E., and G. V. Masaltsev. "EVALUATION OF TOXICITY AND ANTICHOLINESTERASE EFFECT OF A METHOMYL-CONTAINING DRUG WHEN ADMINISTERED TO LABORATORY ANIMALS VIA VARIOUS ROUTES." In The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-44-48.

Full text

Abstract:

Despite a wide range of insecticidal activity and high efficiency, carbamate insecticides require a highly professional approach to its use due to inherent high toxicity to bees, warm-blooded animals and humans, and undesirable feature of its exhibiting toxic properties not immediately, but after prolonged systematic contact. The goal of this work was to evaluate the toxicity of the methomyl-based drug (25% of the active substance) and its anticholinesterase effect in animal experiments when administered via various routes (rats and rabbits). Materials and methods: Experimental toxicological s

APA, Harvard, Vancouver, ISO, and other styles

3

Djelić, Gorica, Duško Brković, Milica Pavlović, and Vesna Veličković. "BIOCHEMICAL RESEARCH OF THE SPECIES ORCHIS MORIO L. FROM ZLATAR." In 2nd International Symposium on Biotechnology. University of Kragujevac, Faculty of Agronomy, 2024. http://dx.doi.org/10.46793/sbt29.31gdj.

Full text

Abstract:

Salep tuber is sourced from young tubers of plants belonging to genera such as Orchis (Orchis morio L, Orchis militaris L, Orchis mascula L, Orchis latifolia L), Ophrys (Ophrys fuciflora (Cr) Haller), Platanthera (Platanthera bifolia (L) Rich,), Anacamptis (Anacamptis pyramidalis (L) Rich), and Gymnadenia (Gymnadenia conopsea (L) RBr) from the Orchidaceae family. Ph.Yug.II categorizes Orchis morio L as salep, aligning with CITES convention and IUCN categories for vulnerable species. As a mucilaginous drug, salep is used as an enema for intestinal catarrh and added to drugs with local irritatin

APA, Harvard, Vancouver, ISO, and other styles

4

Jayasuriya, A. Champa, Anthony Darr, and Nabil A. Ebraheim. "Chemotherapy Drug Encapsulated Poly(Lactic-Co-Glycolic Acid) Nanoparticles." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-14694.

Full text

Abstract:

In order to exhibit pharmacological activity at the bone cancer site, high-dose chemotherapy drugs need to be used. This often causes toxicity and unfavorable systemic adverse effects leading to significant problems to the patient. Since nanoparticles are in subcellular size, they can effectively entered to the cell membrane that could result in higher cellular uptake. In this study, we report preparation and characterization of poly(lactic-co-glycolic acid) - PLGA nanoparticles, which encapsulated with chemotherapy drug cisplatin.

APA, Harvard, Vancouver, ISO, and other styles

5

Sayar, Ersin, and Bakhtier Farouk. "Three Dimensional Dynamic Analysis of a Piezoelectric Valveless Micropump: Effects of Working Fluid." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-88978.

Full text

Abstract:

Coupled structural and fluid flow analysis of a piezoelectric valveless micropump is carried out for liquid transport applications. The valveless micropump consists of trapezoidal prism inlet/outlet elements; the pump chamber, a thin structural layer (Pyrex glass) and a piezoelectric element (PZT-5A), as the actuator. Two-way coupling of forces and displacements between the solid and the liquid domains in the systems are considered where actuator deflection and motion causes fluid flow and vice-versa. Flow contraction and expansion (through the trapezoidal prism inlet and outlet respectively)

APA, Harvard, Vancouver, ISO, and other styles

6

Divetia, Asheesh, Nolan Yoshimura, Guann-Pynn Li, Baruch D. Kuppermann, and Mark Bachman. "Controlled and Programmable Drug Delivery Using a Self-Powered MEMS Device." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38054.

Full text

Abstract:

Controlled and targeted drug delivery systems have gained a lot of interest as they offer numerous benefits such as precise dosing, reduced side-effects and increased patient compliance. We have designed a microelectromechanical systems (MEMS) drug delivery device that is capable of releasing drugs in a controlled and programmable manner. This self-powered device does not require any external stimulation or control to achieve pulsatile release of drugs. The device consists of multiple reservoirs containing the drug embedded together with a water-swellable polymer. The swelling of the polymer u

APA, Harvard, Vancouver, ISO, and other styles

7

Ecker, Tobias, and Christopher G. Rylander. "Modelling of Magnetic Targeting of Therapeutic Nanoparticles in a Two Phase Microvessel Flow." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53834.

Full text

Abstract:

Magnetic particle targeting is a new approach in cancer drug administration which aims to reduce side effects, increase healing rate and reduce treatment time. For this purpose a therapeutic agent is equipped with a magnetizable membrane and administered intravenously. A rare earth magnet can then be used to target cancerous tissue in proximity of the blood vessel.

APA, Harvard, Vancouver, ISO, and other styles

8

Arita, H., та T. Nakano. "INFLUENCE OF β-LACTAM ANTIBIOTICS ON THE PLATELETS IN VITRO EFFECTS OF SOME β-LACTAM ANTIBIOTICS ON THE BIOCHEMICAL RESPONSES OF RAT PLATELETS". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644814.

Full text

Abstract:

The inhibitory mechanism of 3-lactam antibiotics on rat platelets were studied using carbenicil1 in (CBPC) as a representative of the antibiotics. CBPC suppressed all the thrombin-induced cellular responses including shape change, secretion, and aggregation, however, it only suppressed aggregation of ADP-induced responses. This suggests that ADP binding to its own receptor was not affected by the drug while that of thrombin was inhibited. Inhibition of thrombinbinding was confirmed using 125CQSe 0f ADP-stimulated platelets, fibrinogen binding, which has an essential role for ADP-induced primar

APA, Harvard, Vancouver, ISO, and other styles

9

SIMON, M. F., H. CHAP, and L. DOUSTE-BLAZY. "EFFECTS OF SIN 1 ON PLATELET ACTIVATION INDUCED BY THROMBIN IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643423.

Full text

Abstract:

The mechanism of platelet activation is well known. The interaction of agonist such as thrombin, on specific membrane receptor induces phosphatidylinositol-specific phospholipase C activation, with a concomitant formation of two second messengers (from PIP2): inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). IP3 is able to induce a rapid discharge of Ca2+ from internal stores and Ca2+ influx through plasma membrane by unidentified Ca2+ channels linked to receptor activation. The increase of cytoplasmic free calcium concentration leads to the activation of the calcium calmodulin depe

APA, Harvard, Vancouver, ISO, and other styles

10

McGee, James K., Koby Kubrin, Adeel Ahmed, and Michael G. Schrlau. "3D Printed Carbon Nanotube Array Interface for In Vivo Drug Delivery." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-71815.

Full text

Abstract:

The development of gene therapies, small molecules and nanoparticle-based therapeutics in pharmacology have prompted the need for parenteral administration as they possess limited bioactivity, low stability, high specificity and potency. The ability to directly deliver drugs to a specific area offers the capability of minimized required drug quantity, localization of exposure, and limited systemic side effects. Currently, there is no standard for the creation of implantable devices to monitor health status and provide therapeutic treatment. We explored the applications and uses for carbon nano

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Mucous Membrane, drug effects"

1

Tengamnuay, Parkpoom, Achariya Sailasuta, and Garnpimol C. Ritthidej. Efficacy and mechanistic studies of chitosan as nasal absorption enhancer of peptide drugs. Chulalongkorn University, 1998. https://doi.org/10.58837/chula.res.1998.21.

Full text

Abstract:

Objective: To evaluate the safety and efficacy of chitosan (CS) as nasal absorption enhances of peptides. Methods: Two types of chitosans, i.e. CS J (free amine chitosan) and CD G (water-soluble glutamate salt), were evaluate for their masal absorption enhancing effectd on L-Tyr-D-Arg([D-Arg[square]]-Kyotorphic), an enzymatically stable dipeptide, using an in situ rat nasal perfusion technique. The two chitosans were subsequently studies for their possible membrane damaging effects based on measurements of releases mucosal components and histological evaluation. Results: At 0.5% w/v, both CS J

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!