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1

Lancina, Michael G. III. "Nanomedicine Drug Delivery across Mucous Membranes." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4979.

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NANOMEDECINE DRUG DELIVERY ACROSS MUCOUS MEMBRANES By Michael G. Lancina III A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth Univeristy, 2017. Major Director: Dr. Hu Yang, Associate Professor, Chemical and Life Science Engineering Control over the distribution of therapeutic compounds is a complex and somewhat overlooked field of pharmaceutical research. When swallowing a pill or receiving an injection, it is commonly assumed that drug will spread throughout the body in a more
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2

Van, Der Ven Peter F. "Signal propagation in a cell-free system : purinergic signaling among mucous secretory granules from the slug Ariolmax Columbianus /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/6393.

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MEZZARANE, LILIAN A. "Proposta de protocolo clínico para utilização do laser de baixa potência em estomatite protética associada a candidose atrópica." reponame:Repositório Institucional do IPEN, 2007. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11649.

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FREIRE, MARIA do R. S. "Estudo clinico dos efeitos do laser diodo em baixa intensidade de emissao infravermelha para casos de mucosite bucal." reponame:Repositório Institucional do IPEN, 2004. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11198.

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GALLETTA, VIVIAN C. "Desenvolvimento de modelo de indução de mucosite oral por radiação em hamsters. Prevenção e tratamento por laser de baixa potência." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11646.

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BICUDO, LETICIA L. "Utilizacao de LEDS na prevencao de mucosite oral em paciente com linfoma de Hodgkin classico - estudo de caso." reponame:Repositório Institucional do IPEN, 2004. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11199.

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LEITE, PAULA S. A. "Avaliação de dois métodos de análise da microcirculação gengival via fluxometria Laser Doppler." reponame:Repositório Institucional do IPEN, 2007. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11635.

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FRANCA, CYNTHIA M. "Avaliação in vivo dos efeitos preventivo e terapeutico do laser em baixa intensidade em mucosite bucal induzida por quimioterápico em hamsters." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11390.

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ORSI, MARIANE C. E. "Laserterapia e transplante de medula ossea alogenico: efeitos sobre a manutencao da integridade da mucosa oral." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9593.

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EDUARDO, FERNANDA de P. "Efeitos da radiacao laser em baixa intensidade de 650nm e 780nm na prevencao de mucosite oral em pacientes submetidos a transplante de medula ossea." reponame:Repositório Institucional do IPEN, 2003. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11011.

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CUNHA, CATHARINE B. "Avaliacao da eficacia do tratamento para mucosite oral induzida por cinco-fluoracil, com uso de laser de baixa potencia em diferentes comprimentos de onda." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9595.

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KLINGBEIL, MARIA F. G. "Comparação de dois métodos de obtenção celular para cultura primária de queratinócitos bucais humanos." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11481.

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Tyrer, Peter Charles, and n/a. "Targeting M-cells for oral vaccine delivery." University of Canberra. Health Sciences, 2004. http://erl.canberra.edu.au./public/adt-AUC20060427.122012.

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An in vitro model of the follicle-associated epithelia that overlie the Peyer's patches of the small intestine was developed and validated to examine the mechanisms of mucosal antigen sampling. This model displays many phenotypic and physiological characteristics of M cells including apical expression of [alpha]5[beta]l integrin and enhanced energy dependent participate transport. CD4+ T-cells were shown to be an important influence on the development of Mlike cells. The model was used to examine the M cell mediated uptake of several putative whole-cell killed bacterial vaccines. Greater numbe
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14

ALENCAR, ANELISE R. P. "Tratamento da mucosite oral radio e quimioinduzida: comparacao entre protocolo medicamentoso convencional e tratamentos com lasers em baixa intensidade." reponame:Repositório Institucional do IPEN, 2011. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9632.

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ANDRADE, MAIRA F. de. "Comparação dos efeitos da terapia laser de baixa intensidade (lambda=660 nm ou lambda=780 nm) no tratamento de mucosite oral induzida por radiação ionizante em ratos." reponame:Repositório Institucional do IPEN, 2014. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11800.

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GALISTEO, JUNIOR ANDRES J. "Toxoplasma gondii vs radiacao ionizante: imunidade humoral e celular em baço e intestino de camundongos isogênicos imunizados com taquizoítos irradiados por cobalto 60." reponame:Repositório Institucional do IPEN, 2008. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11722.

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Sanahuja, Piera Ignasi. "Caracterización funcional del mucus epidérmico en peces de interés productivo: Metodología no invasiva de identificación de moléculas biomarcadoras y relación con el estado fisiológico." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/666610.

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La acuicultura se ha convertido en una alternativa real y rentable a la pesca extractiva para proporcionar un alimento de un elevado valor nutritivo. Entre las especies de mayor relevancia en la producción acuícola marina del área Mediterránea, se encuentran la dorada (Sparus aurata), la lubina (Dicentrarchus labrax) y más recientemente la corvina (Argyrosomus regius). Si bien se han conseguido grandes adelantos en la mejora de la alimentación y el crecimiento, las metodologías más utilizadas de análisis para determinar su estado fisiológico son de carácter invasivo, ya sea por análisis sobre
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Santos, Carolina Rocio Oliveira. "Uso da anfotericina B lipossomal e de outras drogas no tratamento de pacientes com leishmaniose mucosa: análise da experiência em um serviço de referência para o diagnóstico e tratamento das leishmanioses, 2000-2015." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-26102018-143556/.

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Introdução: As leishmanioses são antropozoonoses que constituem um grave problema de saúde pública por apresentarem um complexo espectro clínico de manifestações e relevante diversidade epidemiológica. Aproximadamente 5% dos pacientes com leishmaniose cutânea não tratada adequadamente irão desenvolver a leishmaniose mucosa (LM). As principais opções terapêuticas disponíveis para esta apresentação da doença são os antimoniais pentavalentes, a pentamidina e as anfotericinas B. As formulações lipídicas da anfotericina B tem sido desenvolvidas na tentativa de melhorar a eficácia e a tolerabilidade
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Sakae, Flavio Akira. "Distribuição das fibras colágenas e do sistema de fibras elásticas na camada superficial da lâmina própria da prega vocal com edema de Reinke." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5143/tde-31102008-173147/.

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A fisiopatologia do edema de Reinke ainda permanece desconhecida e poucos estudos abordam sobre as alterações das proteínas fibrosas, colágeno e elastina, na matriz extracelular da prega vocal com edema de Reinke. Por isso, este estudo foi idealizado para descrever a distribuição das fibras colágenas e do sistema de fibras elásticas do espaço de Reinke com edema de Reinke comparando com a prega vocal normal e com a severidade do edema. Foram obtidas 20 amostras de pregas vocais de indivíduos com edema de Reinke, sendo nove casos com edema de Reinke grau II e 11 casos grau III. Dezessete indiví
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Yip, Aaron. "Effects of Angelica sinensis extract on mucus synthesis and cell proliferation of the stomach." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22227234.

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Sajadi, Tabassi Sayyed Abolghasem. "Some effects of mercaptans on membranes and mucus." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243647.

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22

See, Sarah Bihui. "Outer membrane protein immunity to Pasteurella pneumotropica and the interaction of allergy." University of Western Australia. School of Paediatrics and Child Health, 2010. http://theses.library.uwa.edu.au/adt-WU2010.0103.

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[Truncated abstract] Infectious and allergic diseases of the respiratory tract are major contributors to global mortality, morbidity and economic burden. Bacterial infections such as pneumonia and otitis media are important diseases, especially in children, while allergic diseases such as asthma and allergic rhinitis afflict up to 30% of the world's population. A confounding aspect of respiratory disease is the evidence of a complex relationship between respiratory allergy and respiratory infection, with infection suggested to both promote and prevent the pathogenesis of allergic disease. Addi
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El-Hariri, Linda Mary. "Some effects of biliary constituents on membranes and mucus." Thesis, University of Brighton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277703.

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Law, Yuet Ching. "Specific compartmentalization of Immunoglobulin A antibody secreting cells in mouse salivary glands via the differential expression of chemokines and chemokine receptors /." Diss., CLICK HERE for online access, 2008. http://contentdm.lib.byu.edu/ETD/image/etd2678.pdf.

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Hirbod, Taha. "Mucosal immune responses in HIV-1 exposed uninfected individuals /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-928-9/.

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葉衍葳 and Aaron Yip. "Effects of Angelica sinensis extract on mucus synthesis and cell proliferation of the stomach." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31969884.

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Abdelhamid, Ibrahim Younouss, and О. Г. Аврунін. "CT-signs of nasal cavity of different race for dynamic model of the air flow." Thesis, Харків: ХНУРЕ, 2017. http://openarchive.nure.ua/handle/document/10598.

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Saw, V. P. J. "The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/18576/.

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Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis. Standard systemic immunosuppression controls inflammation, but is limited by toxicity. How well immunosuppressive therapy prevents fibrosis is unknown. The cellular and molecular mechanisms that lead to excessive conjunctival fibrosis in ocular MMP are incompletely understood. Chronic inflammation and repair play an important role, but the conjunctival fibroblasts may also be autonomously activate
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Viljoen, Ianda. "The role of surfactant in, and a comparison of, the permeability of porcine and human epithelia to various chemical compounds." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/1287.

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岑海音 and Hoi-yum Irma Shum. "Interactions of pseudomonas aeruginosa toxins with respiratory mucosa in vitro." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31244725.

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Pinto, Giuliane Jesus Lajos. "Colonização endocervical em gestantes com trabalho de parto prematuro e/ou ruptura prematura de membranas." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313483.

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Orientador: Renato Passini Junior<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-11-27T10:57:27Z (GMT). No. of bitstreams: 1 Pinto_GiulianeJesusLajos_M.pdf: 245675 bytes, checksum: 71fd93a1854439989a54c4faa89da2dc (MD5) Previous issue date: 2005<br>Resumo: Objetivo: estudar a colonização bacteriana endocervical em gestantes com trabalho de parto prematuro e/ou ruptura prematura de membranas (termo e pré-termo). Método: 212 gestantes com trabalho de parto prematuro (TPP) e/ou ruptura prematura de membranas (RPM)
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Salgado, Daniel Cauduro. "Distribuição de colágeno na concha nasal inferior de pacientes com rinite alérgica ou idiopática." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5143/tde-12012015-104722/.

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INTRODUÇÃO: Embora seja reconhecida a existência do espessamento da membrana basal e da fibrose da concha nasal na rinite alérgica, não há estudos descritivos do comportamento da mucosa nasal nos pacientes com rinite idiopática. O propósito desse estudo é descrever possíveis alterações na membrana basal e na lâmina própria da concha nasal inferior em pacientes com rinite alérgica ou idiopática, além do estudo quantitativo das fibras colágenas nesta localização. MÉTODOS: Analisou-se na concha nasal inferior obtida através de turbinectomia bilateral em 28 pacientes - 14 com rinite alérgica e 14
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Fernández, Campos Francisco. "Nanoemulsiones de nistatina para el tratamiento de candidiasis muco-cutáneas." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/83638.

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Se han desarrollado y optimizado dos nanoemulsiones que contienen Nistatina (N1 y N2) para su aplicación en piel y mucosa oral, respectivamente. Estas formulaciones tuvieron un tamaño de gota nanométrico y resultaron ser estables a lo largo del tiempo. Adicionalmente se determinó el comportamiento reológico de ambos sistemas resultando ser fluidos newtonianos. Se evaluó la actividad antifúngica in vitro, observado que la potencia de la nistatina aumentó al ser introducida en las nanoemulsiones, cuando se comparaba con la nistatina libre. El mecanismo de liberación de la nistatina de las nano
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Matos, Ricardo Tedeschi. ""Avaliação do espaço intercelular dilatado da mucosa esofágica antes e após infunsão de ácido clorídrico: marcador da doença do refluxo gastroesofágico (DRGE)"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5147/tde-14092006-153912/.

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O objetivo foi evidenciar a presença do espaço intercelular dilatado do epitélio esofágico após a infusão de ácido clorídrico (HCl) à 0,1N comparando com a infusão de soro fisiológico (SF) em pacientes sem sintomas típicos da DRGE com mucosa esofágica normal e compará-los com os de sintomas típicos e esofagite erosiva. Foram entrevistados e realizaram o exame de endoscopia digestiva alta 60 pacientes destes, 29 foram incluídos no estudo sendo 18 com esôfago normal (9 foram infundidos SF e 9 HCl) e 11 com esofagite erosiva (6 foram infundidos SF e 5 HCl) e foram realizados 4 biópsias da mucosa
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Divekar, Rohit Dilip Zaghouani Habib. "Two aspects of peripheral immune tolerance systemic and mucosal tolerance mechanisms /." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/6868.

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The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on April 1, 2010). Vita. Thesis advisor: Habib Zaghouani. "May 2008" Includes bibliographical references.
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Roos, Stefan. "Adhesion and autoaggregation of Lactobacillus reuteri and description of a new lactobacillus species with mucus binding properties /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5457-3.pdf.

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Hu, Ke-Fei. "ISCOMs as delivery systems for mucosal immunization /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5417-4.pdf.

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Johannesson, Ulrika. "Combined oral contraceptives - impact on the vulvar vestibular mucosa and pain mechanisms /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-279-8/.

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Santos, Amilton Cesar dos. "Expressão das enzimas: citocromo P450 aromatase, NADPH-citocromo P450 redutase e citocromo P450c17 (17-α-hidroxilase/17, 20-liase) na vagina de fêmeas de preás (Galea spixii, Wagler, 1831)." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-24092013-161549/.

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Para a metabolização de hormônios esteroides sexuais é essencial a participação de enzimas esteroidogênicas. A enzima citocromo P450c17 é responsável pela produção de andrógenos e a enzima citocromo P450 aromatase é responsável pela produção de estrógenos, sendo que, ambas as enzimas necessitam formar um complexo com uma enzima parceira, denominada NADPH citocromo P450 redutase, para realizar a metabolização destes hormônios essenciais para a diferenciação sexual. Objetivou-se imunolocalisar as três enzimas acima citadas no tecido vaginal de fêmeas de roedores Galea spixii. Para tanto, o exper
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40

Palmai-Pallag, Timea. "Proteolytic cleavage sites in MUC1,MUC3,MUC4 and MUC12 membrane-tethered mucins." Thesis, Open University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489903.

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The membrane-tethered mucins, which are expressed by various cell types, have different forms: membrane-bound, soluble or secreted. They have been implicated in the pathology of numerous chronic diseases including ovarian and colorectal carcinoma, inflammatory bowel disease, and in cystic fibrosis related epithelial abnormalities.
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41

Quigley, Máire. "Characterisation of CD8 T cells in mucosa associated lymphoid tissue: implications for immune control of HIV-1 infection /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-646-8/.

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42

Mathers, Alicia R. "The effects of the route of viral infection on the balance of T helper immune responses." Morgantown, W. Va. : [West Virginia University Libraries], 2005. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=3825.

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Thesis (Ph. D.)--West Virginia University, 2005<br>Title from document title page. Document formatted into pages; contains ix, 155 p. : ill. Vita. Includes abstract. Includes bibliographical references.
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43

Hemsley, S. "Investigations of mucosal immunology and diseases of mucosal surfaces in marsupials." Thesis, The University of Sydney, 1996. http://hdl.handle.net/2123/19216.

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44

Almeida, Bernice Martha. "A study of basement membranes in normal and neoplastic mucosa of the head and neck." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268060.

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45

Paiva, Nauana Hay. "O papel da bifurcação das projeções da mucosa durante a morfogênese das vilosidades intestinais em embriões de galinhas." Universidade Estadual de Ponta Grossa, 2017. http://tede2.uepg.br/jspui/handle/prefix/2437.

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Submitted by Eunice Novais (enovais@uepg.br) on 2018-02-22T13:31:43Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Nauana Hay Paiva.pdf: 2299112 bytes, checksum: d9eac670828127f267396863b468ab2f (MD5)<br>Made available in DSpace on 2018-02-22T13:31:43Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Nauana Hay Paiva.pdf: 2299112 bytes, checksum: d9eac670828127f267396863b468ab2f (MD5) Previous issue date: 2017-07-07<br>As vilosidades intestinais são estruturas digitiformes da camada mucosa do
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Petris, Carisa Kay. "Identification and characterization of M cells in the mammalian conjunctiva." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4888.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2007.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on December 12, 2007) Vita. Includes bibliographical references.
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Paulsson, Mattias. "Controlled Release Gel Formulations for Mucosal Drug Delivery." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5173-X/.

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48

Wilson, John Edward. "A comparison of alternate mucosal routes of prophylactic immunisation using a mouse model of Helicobacter infection /." View thesis, 2001. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030704.133959/index.html.

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Thesis (M.Sc.) (Honours) -- University of Western Sydney, Hawkesbury, 2001.<br>A thesis submitted for the degree of Master of Science (Honours), Centre for Farming Systems Research, University of Western Sydney, Hawkesbury, 2001. Bibliography : leaves 142-162.
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Ng, William Man Fai. "The effect of volatile thiol compounds on permeability of oral mucosa." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/26508.

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Cumulative clinical and experimental evidence indicates that volatile sulphur compounds (VSC) the principal components of oral malodour, may play an important role in the pathogenesis of periodontal disease. As their (H₂S and CH₃SH) concentrations in gingival sulci increase with the severity of periodontal involvement, the objective of this investigation is to ascertain if they exert an effect on the permeability of oral mucosa. Permeability determinations were performed on excised porcine sublingual mucosal specimens which consisted of non-keratinized epithelium, basal membrane and connectiv
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Torres, Karoll Andrea Alfonso [UNESP]. "Avaliação do desempenho zootécnico, da função da mucosa intestinal e da microbiota ileal quando da substituição do milho pelo sorgo na ração de frangos de corte." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/104936.

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Made available in DSpace on 2014-06-11T19:33:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-24Bitstream added on 2014-06-13T19:04:37Z : No. of bitstreams: 1 torres_kaa_dr_jabo.pdf: 619941 bytes, checksum: e0160fe883801063a539b7087e557875 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Experimento 1: Foram avaliados os efeitos da substituição do milho pelo sorgo na ração para frangos de corte sobre o desempenho, o rendimento de carcaça e partes, a morfometria (densidade de vilos, altura dos vilos, profundidade das criptas, número de células calici
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