Journal articles: 'Mucuna pruriens (L.)'

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Chattopadhyay, Sharmila, S. K. Datta, and S. B. Mahato. "Rapid micropropagation for Mucuna pruriens f. pruriens L." Plant Cell Reports 15, no. 3-4 (December 1995): 271–73. http://dx.doi.org/10.1007/bf00193734.

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Umiyati, Uum. "Allelopathic Inhibition of Nitrifying Bacteria by Legumes." Journal of Tropical Soils 22, no. 2 (May 1, 2017): 125–30. http://dx.doi.org/10.5400/jts.2017.v22i2.125-130.

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The study aimed at understanding the competitive ability of legumes Vigna radiata L. and Mucuna pruriens with weeds and their effects on the activity of nitrifying bacteria in soils and the contents of organic-N in legumes and weeds. The experiment was arranged in a randomized block design with three factors and four replications. The first factor was soil order, i.e. Inceptisol and Vertisol; the second factor was types of legumes, i.e. Vigna radiata L. cultivar Sriti and Mucuna pruriens; and the third factor was weed management, i.e. with weed management and without weed management. The results showed that Vigna radiata L. and Mucuna pruriens indirectly influence the supply of available nitrogen in soils that can be taken up by the coexisted plants or weeds via the inhibition of the growth of Nitrosomonas and Nitrobacter in soils. As a results, the organic-N content in weeds decreases, which is in contrast to the increasing amount of organic-N in Vigna radiata L. and Mucuna pruriens. The results indicated that Vigna radiata L. and Mucuna pruriens are considered as allelophatic legumes, resulting in low organic-N content in weeds. Keywords: Allelopathic, Mucuna pruriens, Nitrosomonas, Nitrobacter, Vigna radiata

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Singh, Shobhit, Pushpraj Gupta, and Rishikesh Gupta. "Evaluation of anti-anxiety activity of Mucuna pruriens." Journal of Drug Delivery and Therapeutics 9, no. 4-A (August 30, 2019): 104–7. http://dx.doi.org/10.22270/jddt.v9i4-a.3420.

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Mucuna pruriens, also known as Velvet Bean, Mucuna pruriens has been used for centuries by Ayurvedic herbalists for overall wellness. Mucuna pruriens provides support for brain function, muscle health and libido. Mucuna pruriens has also been shown to have diuretic effects. It increases tissue resiliency and improves coordination. Mucuna can also increase testosterone levels, which in turn can lead to increased muscle mass and strength. It also supports the nervous and reproductive systems in the body. anti-oxidant activity of M. pruriens has been also demonstrated in vitro by its ability to scavenge DPPH radicals and reactive oxygen species. This is an excellent natural source of L-dopa and 5-hydroxy tryptophan (5-HT) Present study was designed to evaluate the anti-anxiety activity of Mucuna pruriens extract in Swiss albino mice. Three doses of Mucuna pruriens (100, 200,400 mg/kg, p.o.) and standard dose of Buspirone (5 mg/kg, i.p.) were used for evaluation of the anti-anxiety activity. The elevated plus maze (EPM) was used to take as a measure of antianxiety effect. Mucuna pruriens at the doses of 200 mg/kg and 400 mg/kg significantly reduced the time spent and no. of entries in closed arm, increased the time spent and entries into open arm in elevated plus maze (p<0.05) as compared to control group. These results indicate that MP may be possesses antianxiety property. Keywords: Anxiety, Elevated plus maze, Mucuna pruriens, Buspirone, Swiss Albino Mice.

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Prías, Leila, Vicente Painii, Alfonso Ramos, Oswaldo Pesantes, Ana Zambrano, Andrea Vargas, Fabricio Tamayo, and Leonardo Vargas. "Mucuna pruriens, alternativa contra la desnutrición." Investigación, Tecnología e Innovación 1, no. 1 (November 30, 2009): 129–50. http://dx.doi.org/10.53591/iti.v1i1.32.

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El presente artículo investiga la factibilidad de utilización de la leguminosa silvestre Mucuna pruriens (L.) DC. (fabáceae) como una alternativa viable para paliar el déficit nutricional que presenta un amplio porcentaje de niños y niñas que se educan en las escuelas de Guayaquil. Se considera que el bajo rendimiento escolar que se observa en la educación fiscal, está relacionado con la deficiente alimentación de los educandos. Para el efecto, se analizó el valor biológico del frejol Mucuna Pruriens8• Se prepararon y presentaron varios productos hechos a partir de esta leguminosa9, se recolectaron semillas en Vinces para culturizarlas, y con ellas se realizaron los estudios de este trabajo en las Facultades de Ciencias Químicas, Ingeniería Química e ITAV de la Universidad de Guayaquil. Se determinó que el fréjol M. Pruriens no presenta toxicidad aguda oral, tiene un alto valor nutricional al poseer proteínas de buena calidad, aminoácidos esenciales, vitaminas, entre otros. Su nivel de digestibilidad se determinó en el 91,81 %, manteniendo las proteínas después de la cocción. Se evaluó su impacto positivo en la salud de los educandos de una escuela de Guayaquil, comprobándose un aume nto significativo de las proteínas séricas y nivel de madurez en la percepción viso-motriz y desarrollo mental. Con respecto a su factibilidad económica, se determinó una eficiente relación costo/beneficio.

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Sardjono, Ratnaningsih Eko, Iqbal Musthapa, Sholihin ., Atun Qowiyah, and Rahmi Rachmawati. "ACUTE TOXICITY EVALUATION OF ETHANOL EXTRACT OF INDONESIAN VELVET BEANS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 5 (May 1, 2017): 161. http://dx.doi.org/10.22159/ijpps.2017v9i5.16284.

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Objective: This research was conducted to determine the acute toxicity of ethanol extract of velvet beans (Mucuna pruriens) from Indonesia. Extract of Indonesian Mucuna pruriens seeds showed antiparkinson activity due to the presence of L-DOPA inadequate levels. However, research on the toxicity level of Mucuna pruriens seeds from Indonesia is still limited. Acute toxicity data are needed to make Mucuna pruriens as standardized herbal medicine for Parkinson disease.Methods: The dried seed of Mucuna pruriens was extracted by ethanol and suspended with tragacanth to make several dosas of ethanol extract of Mucuna pruriens seeds. Determination of acute toxicity was performed on six groups, each consisting of five Wistar rats. One group was used as a control group; other groups were given ethanol extract of Mucuna pruriens seeds orally at a dose of 5 mg/kg, 50 mg/kg, 300 mg/kg, 2000 mg/kg, and 5000 mg/kg body weight. Symptoms of toxicity, including death, were observed daily for 14 d. At the end of the observation, the surviving Wistar rats were autopsied and the brain, heart, liver, lungs, stomach, spleen, kidneys, and ovaries were weighed to give relative organ weight.Results: There was no mortality observed in all groups. The Wistar rats gained weight within the normal range. The relative organ weights in all groups generally did not show a significant difference. However, the significant differences (P<0.05) were seen in the liver for all treatment groups compared to the control group.Conclusion: The ethanol extract of Mucuna pruriens seeds from Indonesia administered orally has LD50>5000 mg/kg, thus it could be regarded as safe or non-toxic. However, this extract may be potentially toxic to the liver

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Panova, A. S., D. S. Dergachev, M. A. Subotyalov, and V. D. Dergachev. "Review of Mucuna pruriens L. therapeutic potential for Parkinson’s disease." Meditsinskiy sovet = Medical Council, no. 8 (July 16, 2020): 82–87. http://dx.doi.org/10.21518/2079-701x-2020-8-82-87.

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Parkinson’s disease is a multifactorial disorder of the nervous system, the main features of which are progressive degeneration of dopaminergic neurons in the nigra pars compacta nigrostriatal tract and subsequent deficiency of the neurotransmitter dopamine in the areas of the brain, leading to the loss of motor function, the emergence of non-motor symptoms, rigidity, akinesia or bradykinesia, motor block, and decline in cognitive functions. Parkinson’s disease has high prevalence throughout the world, and has no curative treatment in modern medicine. The available drugs such as anticholinergics, levodopa and a DOPA-decarboxylase inhibitor provide symptomatic relief only. Although dopaminergic therapy is the standard treatment of motor disabilities associated with Parkinson’s disease, it does not managed all the aspects of the disease. For this reason, the increasing numbers of patients are looking for more holistic approach to the treatment of this disease. Mucuna pruriens L. – an annual self-pollinating legume plant, can be considered as a potential complementary therapy for patients with Parkinson’s disease, as it is an extremely rich source of levodopa. Numerous studies have shown that Mucuna pruriens extracts restore biochemical and behavioral abnormalities in animals with the experimental model of Parkinson’s disease. The plant also demonstrates some antioxidant activity. The clinical effects of high-dose Mucuna pruriens are similar to levodopa, but have a more favorable tolerance profile. If long-term use of Mucuna pruriens proves safe and effective in controlled clinical trials, it could become a sustainable complementary therapy for the treatment of Parkinson’s disease, especially in low-income countries.

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Liadi, Vivian Citra, Ni Wayan Wisaniyasa, and Ni Nyoman Puspawati. "STUDI SIFAT FUNGSIONAL DAN KIMIA TEPUNG KECAMBAH KACANG KORO BENGUK (Mucuna pruriens L.)." Jurnal Ilmu dan Teknologi Pangan (ITEPA) 8, no. 2 (June 21, 2019): 131. http://dx.doi.org/10.24843/itepa.2019.v08.i02.p03.

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The purpose of this study was to determine the functional and chemical properties of mucuna bean sprout flour. This study was conducted using 48 hour germination and without germination of mucuna bean, and each treatment was repeated three times. Mucuna bean flour and mucuna bean sprouts flour were tested for rendemen, functional properties (water absorption, oil absorption, swelling volume, and solubility), and chemical properties (moisture content, ash content, protein content, fat content, carbohydrate content, and HCN content). The results showed that germination of mucuna bean had a very significant effect on rendemen, water absorption, oil absorption, ash content, moisture content, a significant effect on fat content, carbohydrate content, and had no significant effect on swelling volume, solubility, protein content, and HCN content. The results showed that rendemen of mucuna bean sprout flour was 63.93% (db), the functional properties of mucuna bean sprout flour were water absorption 1.67 ml H2O/g solid, oil absorption 2.17 ml oil/g solid, swelling volume 8.68 ml/g, and solubility 25.76%, while the chemical properties of mucuna bean sprout flour were water content 8.10%, ash content 2.87%, protein content 36.33%, fat content 10.77%, carbohydrate content 41.92%, and HCN content 5.39 mg/kg.

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Vora, Ragni, Ambika N. Joshi*, and Nitesh C. Joshi. "Comparison of extraction efficiency of various methods to extract L-DOPA from Mucuna pruriens (L.) DC." International Journal of Bioassays 6, no. 04 (April 2, 2017): 5343. http://dx.doi.org/10.21746/ijbio.2017.04.003.

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Mucuna pruriens seeds are noted to be a natural source of L-DOPA and are also used as a substitute for the synthetic L-DOPA. In the present study; attempts are made to develop suitable method(s) for extraction of L-DOPA from the powdered seeds of Mucuna pruriens using different solvents and conditions. The Seed powder was subjected to 7 different extraction methods and Method 1 was subjected to various solvent concentrations. Some methods used de-fatting procedure, either the method was cold maceration or in high temperature. Soxhlet extraction was also used in one of the extraction methods. All the extracts were analyzed using RP-HPLC. Mobile Phase used was Water: Methanol: AcetoNitrile (100:60:40) (v/v) containing 0.2% Triethylamine, pH = 3.3 and monitored at 280 nm with variable wavelength UV detector. The extraction was best with Methanol Water mixture in a cold maceration technique and overall gives good extraction efficiency of 13.36 % L-DOPA and id the best method giving highest extraction efficiency. The De-fatting method was the 2nd best methods giving approximately 8.8% L-DOPA and Method 5 viz, heat reflux method gives 8.7% L-DOPA making it the 3rd best method. There are not many studies done for optimization of extraction technique for L-DOPA despite an extensive work is reported for isolation, identification and pharmacological activities of L-DOPA from various plant sources. Keeping this in view, present investigation was done to study the extraction efficiency of various extraction methods of L-DOPA content in seed extracts of Mucuna pruriens and compare it.

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Azmi, Nuriza Ulul, Astari Rachma Nityasa, and Fadlina Chany Saputri. "Antithrombotic Effect of Mucuna pruriens L. and Coriandrum sativum." Pharmacognosy Journal 11, no. 2 (February 18, 2019): 413–17. http://dx.doi.org/10.5530/pj.2019.11.64.

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Longhi, Joy Ganem, Elisa Perez, Jair José de Lima, and Lys Mary Bileski Cândido. "In vitro evaluation of Mucuna pruriens (L.) DC. antioxidant activity." Brazilian Journal of Pharmaceutical Sciences 47, no. 3 (September 2011): 535–44. http://dx.doi.org/10.1590/s1984-82502011000300011.

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Mucuna pruriens (L). Dc is a plant of the Fabaceae family, commonly known as velvet bean, itchy bean, chiporro bean, mucuna, among others. This plant has several medicinal properties, including its potential to treat Parkinson's disease (PD). International studies have shown that this plant surpasses the benefits of the substance levodopa in the treatment of PD. Taking into account that nerve cells are highly sensitive to oxidative substances, this study evaluated the antioxidant activity of mucuna and compared it to that of levodopa. The plant seeds' phenolic concentration was quantified by using the Folin-Denis reagent and the antioxidant activity assays were performed by using three different methods: the reduction of the phosphomolybdenium complex, the reduction of radical 1,1-diphenyl-2-picrylhydrazyl (DPPH•) and the formation of radical monocation ABTS•+, from the acid [2-2'-azinobis (3-ethylbenzothiazoline-6-sulfonate)]. Results showed that M. pruriens presents high antioxidant capacity, although not superior to isolated levodopa antioxidant capacity. Therefore, further studies should be performed to elucidate the activity of this plant in humans.

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Chittasupho, Chuda, Sarin Tadtong, Suwanna Vorarat, and Narisa Kamkaen. "Physical, Chemical, and Microbiological Stability of Mucuna pruriens Effervescent Powders and Suspension." Key Engineering Materials 859 (August 2020): 145–50. http://dx.doi.org/10.4028/www.scientific.net/kem.859.145.

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Mucuna pruriens is a tropical leguminous plant containing L-dopa which is the main active ingredient for Parkinson’s disease therapy. The objective of this study was to investigate the physical, chemical, and microbiological stability of M. pruriens seed extract effervescent powders and suspension. The effervescent powders and suspension were prepared using freeze dried M. pruriens seed extract and were stored at 4 °C, 30 °C, and 45 °C. Physical stability was evaluated by observing appearance and determining rheological behavior. Chemical stability was evaluated by HPLC assay of L-dopa content in the formulation. Bacterial, fungal and mold contaminations were assessed by 3MTM PetrifilmTM count plates. Both formulations showed good physical stability. The degradations of L-dopa in effervescent powders and suspension were fitted to pseudo-zero order and second order kinetic models, respectively. M. pruriens seed extract effervescent powders was found to have the longest half-life, about 112 days, when it was stored at 4 °C. The results suggested that M. pruriens seed extract should be formulated in effervescent powders and stored at 4°C to prevent physical and chemical degradation.

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Lima, Andréa Aparecida de, Paulo Ivan Fernandes Júnior, Samuel Ribeiro Passos, Fernanda Santana de Paulo, Sumaya Mário Nosoline, Sérgio Miana de Faria, José Guilherme Marinho Guerra, Norma Gouvêa Rumjanek, and Gustavo Ribeiro Xavier. "Diversidade e capacidade simbiótica de rizóbios isolados de nódulos de Mucuna-Cinza e Mucuna-Anã." Revista Brasileira de Ciência do Solo 36, no. 2 (April 2012): 337–48. http://dx.doi.org/10.1590/s0100-06832012000200003.

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As espécies de mucuna são muito utilizadas como adubos verdes, e poucas informações estão disponíveis a respeito dos rizóbios nativos capazes de nodulá-las. O objetivo deste trabalho foi avaliar a diversidade e a capacidade simbiótica de isolados bacterianos de nódulos de mucuna-cinza (Mucuna pruriens (L.) DC.) e mucuna-anã (Mucuna deeringiana (Bort.) Merr.). As bactérias foram isoladas de nódulos de mucunas cinza e anã cultivadas em vasos com solos de um sistema de produção agroecológica. Foram isoladas 160 bactérias, sendo 80 de mucuna-anã e 80 de mucuna-cinza, que foram autenticadas e selecionadas para avaliação da capacidade simbiótica. A diversidade dos isolados foi avaliada por meio das características culturais em meio de cultura YMA e da técnica de análise de restrição do produto de PCR do gene 16S rDNA. A inoculação de cinco isolados em mucuna-cinza e dois em mucuna-anã apresentou elevada biomassa da parte aérea. A maioria dos isolados apresentou crescimento rápido e acidificou o meio de cultura. A análise de restrição demonstrou que as bactérias isoladas apresentam baixa similaridade com estirpes de referência, sugerindo a existência de isolados pertencentes a novos grupos, capazes de nodular as mucunas anã e cinza.

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Sandoval Fernández, Liseth, Andrés Zúñiga Orozco, Alexander Mendoza Luna, Karla Montero Jara, and Wagner Peña Cordero. "Efecto de la incorporación de Zeolita natural y Mucuna pruriens en el cultivo de arroz (Oryza sativa L.) bajo condiciones controladas en Upala, Alajuela, Costa Rica." Repertorio Científico 23, no. 1 (June 30, 2020): 19–28. http://dx.doi.org/10.22458/rc.v23i1.2941.

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Se utilizó una fuente de abono verde, Mucuna pruriens a una dosis de 120 g/m2 y otra fuente de mineral Zeolita con dosis de 152 g/m2, en 7 tratamientos. Se logró determinar que el tratamiento de Mucuna pruriens y fertilización como el mejor en rendimiento, incluso mejor que el testigo comercial y otros tratamientos, además con una calidad de grano aceptable, también contribuyendo en una utilización eficiente del nitrógeno en la planta y una buena incorporación de materia orgánica al suelo. Otros efectos y factores involucrados bajo las condiciones de este ensayo son discutidos.

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Ladino Manjarrés, Diego Alexander, and Harold Bastidas López. "Componentes naturales para el control de antracnosis (Colletotrichum gloeosporoides) en guanabana (Annona muricata L.)." Revista Sistemas de Producción Agroecológicos 8, no. 1 (June 30, 2017): 12–26. http://dx.doi.org/10.22579/22484817.693.

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El cultivo de guanábana (Annona muricata L.) es uno de los más populares en Colombia, puesto que su fruto es muy consumido y requiere de buenos cuidados para su comercialización, en los últimos años se ha ido incrementando el área sembrada. La aplicación de productos químicos a estos árboles para la disminución de la enfermedad que los afecta, antracnosis (Colletotrichum gloeosporoides) es una constante; por lo tanto este proyecto investigó sobre otras alternativas probando productos orgánicos elaborados a base de extractos vegetales o biofertilizantes que puedan disminuir y controlar la incidencia y severidad de esta enfermedad, con el fin de reemplazar los agroquímicos que dejan residualidad y pueden ser perjudiciales para la salud humana. Para estas pruebas se establecieron los siguientes tratamientos: Mucuna pruriens (mucuna) (T1), Datura stramonium (borrachero) (T2) y un biofertilizante (T3) para comparar la severidad de la enfermedad contra un testigo (T0); se aplicó un diseño completamente al azar, cuatro tratamientos, tres replicaciones con tres unidades experimentales, se realizaron evaluaciones a los siete, doce y dieciocho días después de la aplicación de estos productos. El porcentaje de disminución con respecto a la severidad inicial que se tomó como cero (0), arroja que los productos que dieron un resultado positivo (P<0.05) en las aplicaciones de manera progresiva contra la enfermedad antracnosis fueron: el extracto con la planta Mucuna pruriens y el biofertilizante siendo de 78.35 Vs 18.36 y 50.81 Vs 20%, respectivamente comparando la severidad inicial con la presentada a los 18 días después de la aplicación de productos. Se concluye que los mejores tratamientos fueron el de Mucuna pruriens seguido del biofertilizante.

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Lahiri, Kotisree, Madhumita J. Mukhopadhyay, and Sandip Mukhopadhyay. "Enhancement of L-DOPA Production in Micropropagated Plants of two Different Varieties of Mucuna pruriens L., Available in India." Plant Tissue Culture and Biotechnology 21, no. 2 (December 31, 2011): 115–25. http://dx.doi.org/10.3329/ptcb.v21i2.10224.

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Reports on increment in L-DOPA content in micropropagated plants, regenerated through a simple technique following shoot bud multiplication in four strains of two different varieties of Mucuna pruriens are made. Nodal segments from in vitro grown seedlings were cultured on modified MS with various concentrations and combinations of BAP, 2iP, Kn either alone or with NAA. Highest shoot regeneration from the callus was achieved in modified MS fortified with BAP at 1.33 µM level. The regenerated shoots were rooted in vitro in half-strength of liquid MS supplemented with various levels of NAA (0.54 - 10.7 mM) or IBA (0.49 - 9.85 mM). However, roots of superior quality were obtained at 5.4 mM NAA level after two weeks in culture. The regenerants were acclimatized for 2 - 3 weeks and about 85% survival rate was observed after transferring to the field. Both chromosome number stability as well as stability in nuclear DNA contents of the regenerants of all these strains was recorded with complete absence of aneuploidy. The different strains have revealed two to three-folds increase in L-DOPA contents in the cultured plants. The L-DOPA concentration in leaves of the regenerated plants varied from11.85 - 15.42 mg/g dry weight in all these accessions. However, the highest amount was observed in the wild strain of M. pruriens. This is the first report on enhancement of L-DOPA content in differentiated tissue of cultured plants of both the varieties of M. pruriens. Key words: L-DOPA, Micropropagation, Mucuna pruriens, Nuclear DNA D. O. I. 10.3329/ptcb.v21i2.10224 Plant Tissue Cult. & Biotech. 21(2): 115-125, 2011 (December)

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Paudyal, Som Prasad, and Vimal NP Gupta. "Bio-chemical characterization of rhizobia isolated from root nodules of Velvet bean (Mucuna pruriens L.)." Our Nature 15, no. 1-2 (December 25, 2017): 7–12. http://dx.doi.org/10.3126/on.v15i1-2.18788.

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Rhizobia are the symbiotic bacteria found in the soil which have potential ability to convert atmospheric di-nitrogen into usable form. A total of ten rhizobial strains were isolated from the root nodules of a medicinal legume Mucuna pruriens (L.) that commonly grow in the foothills of the Himalaya. All the ten strains isolated from different locations of same area were morphologically, biochemically and physiologically characterized based on the Bergey’s Manual of systematic Bacteriology. They were tested for the antibiotics sensitivity. The isolates showed high sensitivity to amoxicillin and least to erythromycin. Authentication test was done in eleven legumes but shown nodulations only in Trigonella foenum-graecum, Mucuna pruriens and Medicago sativa. The morphology, physiology, biochemical and infection test studies carried out justifies that the bacteria isolated belonged to the species of Rhizobium meliloti.

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Vora, Ragni, Ambika N. Joshi, and Nitesh Chandulal Joshi. "Comparison Of L-Dopa Content In Three Species Of Genus Mucuna By Different Extraction Techniques." Annals of Plant Sciences 7, no. 1 (January 1, 2018): 1973. http://dx.doi.org/10.21746/aps.2018.7.1.10.

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In the present study, attempts are made to develop suitable method(s) for extraction of L-DOPA from the powdered seeds of 3 species of Mucuna using different solvents and conditions. The seed powder of both plants was subjected to 6 different extraction methods, with different solvent ratios. All the extracts were analyzed using RP-HPLC and was validated according to The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use guidelines. The L-DOPA extraction was best with Methanol Water mixture in a cold maceration technique and overall gives good extraction efficiency in all the three plants giving concentrations of 5.03%, 13.36 % and 16.78% of L-DOPA in Mucuna gigantea, Mucuna pruriens and Mucuna monosperma, respectively. The present investigation was done to study the extraction efficiency of various extraction methods of L-DOPA content in seed extracts of Mucuna and compare it.

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Milla, Meidona Nurul, Yani Istadi, Vania Shaula, Deastri Anjeas Wari, Chntyia Dwi Cahyani Puspitasari, and Umar Usman Bin Sef. "The Potential Effect of Mucuna pruriens Seed Extract on Sperm Quality experimental study on mice exposed to cigarette smoke." Bangladesh Journal of Medical Science 20, no. 4 (June 18, 2021): 768–73. http://dx.doi.org/10.3329/bjms.v20i4.54132.

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Background: Infertility has been more common problems among couple of reproductive age. One of the factors causing this disorder is unhealthy environmental factors including exposure to cigarette smoke. Polynuclear aromatic hydrocarbons (PAHs) in cigarette smoke can cause testicular atrophy, while the free radicals can inhibit the stages of spermatogenesis, and nicotine in cigarettes affects the brain dopamine levels affecting the levels of GnRH, and subsequently affect the levels of FSH and LH needed in spermatogenesis. The use of Mucuna pruriens seed extract containing antioxidants and L-dopa is expected to improve the quality of sperm after exposure to cigarette smoke. Objective: This study aimed to determine the effect of Mucuna pruriens seed extract on the sperm quality in mice exposed to cigarette smoke. Methods: This study was an experimental study with a post test only control group design. A total of 20 mice were divided into 4 groups of five mice each. All groups were exposed to cigarette smoke. Group 1 was the negative control exposed to cigarette smoke. Groups 2, 3, 4 were exposed to cigarettes smoke and given Mucuna pruriens seed extracts at the dose of 250; 300; and 350 mg/Kg BW/day. Parameters of sperm quality included concentration, morphology, motility and viability. Results: Post hoc tests showed there were significant differences among treatment groups. Conclusion: the administration of Mucuna pruriens seed extract affects the sperm quality of BALB/c mice exposed to cigarettes smoke. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.768-773

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Correia, Marcos Vidal, Leandro C. R. Pereira, Luis De Almeida, Robert L. Williams, Joseph Freach, Harry Nesbitt, and William Erskine. "Maize-mucuna (Mucuna pruriens (L.) DC) relay intercropping in the lowland tropics of Timor-Leste." Field Crops Research 156 (February 2014): 272–80. http://dx.doi.org/10.1016/j.fcr.2013.10.011.

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Raina, Archana P., J. B. Tomar, and M. Dutta. "Variability in Mucuna pruriens L. germplasm for L-Dopa, an anti parkinsonian agent." Genetic Resources and Crop Evolution 59, no. 6 (May 9, 2012): 1207–12. http://dx.doi.org/10.1007/s10722-012-9836-4.

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Modi, Ketan Pravinbhai, Natvarlal Manilal Patel, and Ramesh Kishorilal Goyal. "Estimation of L-Dopa from Mucuna pruriens LINN and Formulations Containing M. pruriens by HPTLC Method." CHEMICAL & PHARMACEUTICAL BULLETIN 56, no. 3 (2008): 357–59. http://dx.doi.org/10.1248/cpb.56.357.

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Saragih, Siti Hartati Yusida, Khairul Rizal, and Kamsia Dorliana Sitanggang. "Induksi Mutasi Kara Benguk (Mucuna pruriens L.) Menggunakan Iradiasi Sinar Gamma." Agrosains : Jurnal Penelitian Agronomi 22, no. 2 (October 1, 2020): 105. http://dx.doi.org/10.20961/agsjpa.v22i2.44151.

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Breeding kara benguk with mutation induction techniques using gamma ray radiation is expected to produce genetic diversity. The purpose of the study is to determine the value of Lethal Dose 50 (LD50) and obtain the genetic diversity of the kara benguk plant. The research was conducted at PAIR BATAN and Agrotechnology experiment, Universitas Labuhanbatu from May-July 2020. The planting material used was kara benguk seeds. The method used was Randomized Complete Group Design (RCGD) with one factor which was dose of irradiation with six levels (0, 200, 250, 300, 350 and 400 Gy) and three replications. Each replication consisted of 20 plants, so there are a total of 360 experimental plants. The results showed that the value of LD50 kara benguk in 3 weeks after planting was 281,472 Gy. Gamma ray irradiation increases the high genetic diversity of plants and the number of leaves at a dose of 350 Gy.

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Huizing, H. J., R. Wijnsma, S. Batterman, Th M. Malingré, and H. J. Wichers. "Production of L-DOPA by cell suspension cultures of Mucuna pruriens." Plant Cell, Tissue and Organ Culture 4, no. 1 (March 1985): 61–73. http://dx.doi.org/10.1007/bf00041657.

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Wichers, H. J., R. Wijnsma, J. F. Visser, TH M. Malingré, and H. J. Huizing. "Production of L-DOPA by cell suspension cultures of Mucuna pruriens." Plant Cell, Tissue and Organ Culture 4, no. 1 (March 1985): 75–82. http://dx.doi.org/10.1007/bf00041658.

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Wichers, H. J., T. M. Malingr�, and H. J. Huizing. "Induction of phenoloxidase in cell suspension cultures of Mucuna pruriens L." Planta 165, no. 2 (1985): 264–68. http://dx.doi.org/10.1007/bf00395049.

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Widhiyastuti, Endang, and Mastuti Widi Lestari. "Pengaruh Pemberian Koro Benguk (Mucuna pruriens L) terhadap Kadar Gula Darah Tikus Diabetes Melitus yang Diinduksi Streptozotocin." Borneo Journal of Medical Laboratory Technology 2, no. 2 (April 30, 2020): 136–40. http://dx.doi.org/10.33084/bjmlt.v2i2.1386.

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Diabetes which is well-known in the community as diabetes in Indonesia is a chronic disease, which occurs when the pancreas does not produce enough insulin or when the body cannot utilize the insulin produced by its own products. The Provision of antioxidants in DM mice can reduce blood sugar levels. One of the herbs that can be used for control and management of blood sugar in diabetes is swollen koro. Koro Benguk (Mucuna pruriens L) is a plant that can be used as an alternative treatment because it contains antioxidants that can maintain health without causing toxic effects. The purpose of this study was to determine whether there is an effect of giving koro benguk coffee (Mucuna pruriens L) on blood sugar levels of Streptozotocin-induced Diabetes Mellitus Rats. This study is an experimental study of Sprague Dawley mice. A total of 35 male wistar rats were divided into 5 groups each: normal control (K1); diabetes control (K2); diabetic rats were given a large coffee extract 0.63 mg / g BW rat (P1); diabetic rats were given a large infusion of coffee koro 1.26 mg / g BW rats (P2). Diabetic rats were given an infusion of coffee koro benguk20,52 mg / g BW rats. Fasting blood glucose (GDP) levels were analyzed weekly for 3 weeks using the GOD-PAP method. The results of the study showed a decrease in blood sugar for 4 times the observation time in almost all treatment groups except the positive control group. The conclusions in this study were the provision of related coffee (Mucuna pruriens L) can reduce fasting blood glucose levels in Sprague Dawley rats with diabetes models significantly compared to controls.

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Motta, E. V. S., N. C. C. Pinto, A. P. N. Duque, R. F. Mendes, P. M. Q. Bellozi, and E. Scio. "Atividades antioxidante, antinociceptiva e anti-inflamatória das folhas de Mucuna pruriens (L.) DC." Revista Brasileira de Plantas Medicinais 15, no. 2 (2013): 264–72. http://dx.doi.org/10.1590/s1516-05722013000200015.

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A espécie Mucuna pruriens (L.) DC. (Fabaceae) é popularmente conhecida no Brasil como "café berão" e "pó de mico". Suas sementes são bastante estudadas sendo empregadas na medicina popular para o tratamento de desordens nervosas e do aparelho reprodutor, porém poucas informações sobre a composição química e atividade farmacológica das folhas dessa espécie são descritas na literatura. Assim, os objetivos desse estudo foram: a determinação do perfil fitoquímico, a avaliação da atividade antioxidante in vitro, e a avaliação das atividades anti-inflamatória e antinociceptiva in vivo do extrato metanólico das folhas de M. pruriens nas concentrações de 100 e 300 mg/kg. O estudo fitoquímico foi realizado por meio da pesquisa qualitativa dos constituintes químicos e determinação quantitativa do teor de fenóis totais e flavonoides. O potencial antioxidante foi avaliado pelos métodos do DPPH e poder de redução. As atividades anti-inflamatória e antinociceptiva foram a ante foi promissor, com CI50 de 13,2∝g/mL pelo método do DPPH, e CE50 de 47,9∝g/mL pelo método que avalia o poder de redução. Em relação à atividade anti-inflamatória, o extrato foi capaz de inibir o edema de orelha em 63% (100mg/kg) e 28% (300mg/kg). Quanto à atividade antinociceptiva, houve redução do número de contorções abdominais de 64% (100 mg/kg) e 69% (300 mg/kg). Estes resultados indicam que M. pruriens apresenta um potencial farmacológico promissor e reforçam o conceito de que a pesquisa de plantas com usos etnofarmacológicos pode revelar um número substancial de respostas em ensaios in vitro e in vivo.

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Nascente, Adriano Stephan, José Dambiro, and Clérico Constantino. "Effects of grain-producing cover crops on rice grain yield in Cabo Delgado, Mozambique." Revista Ceres 64, no. 6 (December 2017): 607–15. http://dx.doi.org/10.1590/0034-737x201764060007.

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ABSTRACT Besides providing benefits to the environment such as soil protection, release of nutrients, soil moisture maintenance, and weed control, cover crops can increase food production for grain production. The aim of this study was to evaluate the production of biomass and grain cover crops (and its respective effects on soil chemical and physical attributes), yield components, and grain yield of rice in Mozambique. The study was conducted in two sites located in the province of Cabo Delgado, in Mozambique. The experimental design was a randomized block in a 2 × 6 factorial, with four repetitions. Treatments were carried out in two locations (Cuaia and Nambaua) with six cover crops: Millet (Pennisetum glaucum L.); namarra bean (Lablab purpureus (L.) Sweet), velvet beans (Mucuna pruriens L.), oloco beans (Vigna radiata (L.) R. Wilczek), cowpea (Vigna unguiculata L.), and fallow. Cover crops provided similar changes in chemical and physical properties of the soil. Lablab purpureus, Vigna unguiculata, and Mucuna pruriens produced the highest dry matter biomass. Vigna unguiculada produced the highest amount of grains. Rice grain yields were similar under all cover crops and higher in Cuaia than Nambaua.

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FUJII, Yoshiharu, Tomoko SHIBUYA, and Tamaki YASUDA. "L-3,4-dihydroxyphenylalanine as an allelochemical candidate from Mucuna pruriens (L). DC. var. utilis." Agricultural and Biological Chemistry 55, no. 2 (1991): 617–18. http://dx.doi.org/10.1271/bbb1961.55.617.

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Lal, R. K. "Genotype selection for agronomical trait – seed yield in kewachh { Mucuna pruriens (L.)}." Industrial Crops and Products 65 (March 2015): 62–70. http://dx.doi.org/10.1016/j.indcrop.2014.11.033.

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Bellani, Lorenza, Stefania Giglioni, and Simonetta Muccifora. "Protein Characterization of Protein Bodies from Cotyledons of Mucuna pruriens (L.) DC." Plant Foods for Human Nutrition 68, no. 1 (January 19, 2013): 47–51. http://dx.doi.org/10.1007/s11130-012-0331-z.

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Haro, Hadou, Kadidia Semde, Kadidiata Bahadio, and Kadidia B. Sanon. "Effet de l’inoculation mycorhizienne avec des souches des champignons mycorhiziens arbusculaires sur la croissance de Mucuna pruriens (L.) DC en condition contrôlée." International Journal of Biological and Chemical Sciences 14, no. 3 (June 19, 2020): 1065–73. http://dx.doi.org/10.4314/ijbcs.v14i3.32.

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Au Burkina Faso, l’élevage occupe plus de 80% des ménages ruraux et constitue le troisième produit d’exportation après l’or et le coton. De type extensif, cet élevage est basé essentiellement sur l’exploitation des ressources naturelles. Ainsi, il doit s’adapter aux grandes variations saisonnières et interannuelles des ressources en biomasse végétale et en eau. Or les aléas climatiques, l’étendue et la qualité des pâturages, de même que les contraintes rendent l’activité pastorale souvent précaire. C’est ainsi que cette étude a été initiée dans le but de contribuer à améliorer la production fourragère. Dans cette étude, Mucuna pruriens a été cultivé en serre et inoculé avec deux inocula de champignons mycorhiziens arbusculaires. Les paramètres de croissance ont été mesurés à 30 et 60 jours après semis. La biomasse aérienne, racinaire et totale a été évaluée à 60 jours après semis. Les résultats montrent une amélioration de la croissance en hauteur du mucuna de 225,76%, de la biomasse aérienne de 56,79%, la biomasse racinaire de 70% et la biomasse totale de 61,16% par rapport au témoin non inoculé. Cette étude a montré des résultats intéressants et mérite d’être approfondie par des essais in situ tout en étendant l’étude sur les inoculations rhizobiennes.Mots clés : Mucuna, inoculation mycorhizienne, champignons mycorhiziens arbusculaires. English Title: Effect of mycorrhizal inoculation with arbuscular mycorrhizal fungi strains on Mucuna pruriens (L.) DC growth under controlled conditionIn Burkina Faso, breeding occupies more than 80% of rural households and is the third export product after gold and cotton. Extensive type, this breeding is based essentially on the exploitation of natural resources. Thus, it must adapt to large seasonal and interannual variations in plant biomass and water resources. Climatic hazards, the extent and quality of pastures, as well as constraints make pastoral activity often precarious. Therefore, this study was initiated with the aim of helping to improve forage production. In this study, Mucuna pruriens was grown in a greenhouse and inoculated with two inocula of arbuscular mycorrhizal fungi. The growth parameters were measured at 30 and 60 days after sowing. Shoot, root and total biomass was evaluated at 60 days after sowing. The results show an improvement in the height growth of mucuna by 225.76%, shoot biomass by 56.79%, root biomass by 70% and total biomass by 61.16% compared to the control. This study showed interesting results and deserves to be deepened by in situ tests while extending the study of rhizobial inoculations. Keywords: Mucuna, mycorrhizal inoculation, arbuscular mycorrhizal fungi

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Concessao, Preethi, Laxminarayana Kurady Bairy, and Archana Parampalli Raghavendra. "Protective effect of Mucuna pruriens against arsenic-induced liver and kidney dysfunction and neurobehavioral alterations in rats." August-2020 13, no. 8 (2020): 1555–66. http://dx.doi.org/10.14202/vetworld.2020.1555-1566.

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Background and Aim: Intoxication of arsenic in rats is known to result in neurological effects as well as liver and kidney dysfunction. Mucuna pruriens has been identified for its medicinal properties. The aim of the study was to investigate the protective effect of aqueous seed extract of M. pruriens on sodium arsenite-induced memory impairment, liver, and kidney functions in rats. Materials and Methods: The experiment was divided into short-term treatment (45 days) and long-term treatment (90 days), with each group divided into nine sub-groups consisting of six animals each. Sub-groups 1 and 2 served as normal, and N-acetylcysteine (NAC) controls, respectively. Sub-groups 3-9 received sodium arsenite in drinking water (50 mg/L). In addition, sub-group 4 received NAC (210 mg/kg b.wt) orally once daily, sub-groups 5-7 received aqueous seed extract of M. pruriens (350 mg/kg b.wt, 530 mg/kg b.wt, and 700 mg/kg b.wt) orally once daily and sub-groups 8 and 9 received a combination of NAC and aqueous seed extract of M. pruriens (350 mg/kg b.wt and 530 mg/kg b.wt) orally once daily. Following the treatment, the blood was drawn retro-orbitally to assess the liver (serum alanine transaminase [ALT], serum aspartate transaminase, and serum alkaline phosphatase) and kidney (serum urea and serum creatinine) functions. Learning and memory were assessed by passive avoidance test. Animals were sacrificed by an overdose of ketamine, and their Nissl stained hippocampal sections were analyzed for alterations in neural cell numbers in CA1 and CA3 regions. Results: In the short-term treatment, groups administered with M. pruriens 530 mg/kg b.wt alone and combination of NAC + M. pruriens 350 mg/kg b.wt exhibited a significant improvement in memory retention, less severe neurodegeneration, and decrease in serum ALT levels. In long-term treatment, groups administered with M. pruriens 700 mg/kg b.wt alone and combination of NAC+M. pruriens 350 mg/kg b.wt, respectively, showed better memory retention, decreased neural deficits, and reduced levels of kidney and liver enzymes. Conclusion: The seed extract of M. pruriens showed significant enhancement in memory and learning. The number of surviving neurons in the CA1 and CA3 regions also increased on treatment with M. pruriens. Serum ALT, serum urea, and serum creatinine levels showed significant improvement on long-term treatment with M. pruriens.

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Inara Da Silva Araujo, Tancredo Augusto Feitosa de Souza, Karla Selene Forstall-Sosa, Edjane de Oliveira Lucena, Samuel Inocêncio Alves da Silva, and Djail Santos. "Pennisetum glaucum (L.) R. Br. vs. Mucuna pruriens (L.) DC.: efeito do cultivo de espécies de plantas não leguminosas e leguminosas sobre a comunidade de fungos micorrízicos nativos de solos arenosos." Acta Biológica Catarinense 7, no. 2 (June 30, 2020): 48–57. http://dx.doi.org/10.21726/abc.v7i2.148.

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Plantas pertencentes a distintas famílias botânicas apresentam efeitos diferentes na composição da comunidade de fungos micorrízicos arbusculares (FMAs) nativos. Realizou-se um estudo para determinar a influência de duas espécies de plantas de cobertura – Pennisetum glaucum (L.) R. Br. e Mucuna pruriens (L.) DC. – sobre a composição da comunidade de FMAs nativos de solos arenosos da zona do brejo paraibano. Para tanto, os tratamentos foram dispostos em delineamento em blocos inteiramente casualizados, com dois tratamentos, três blocos e dez repetições. Observaram-se diferenças significativas entre as plantas de cobertura para o número de glomerosporos (t = 5,79, p < 0,05) e o índice de diversidade de Shannon (t = 5,31, p < 0,05). De forma geral, verificou-se que a comunidade micorrízica presente na rizosfera de P. glaucum apresentou índice de diversidade superior em 4,06% quando comparada com a comunidade micorrízica presente em M. pruriens. Por outro lado, encontrou-se maior número de glomerosporos (> 38,28%) no solo rizosférico de M. pruriens quando comparado com P. glaucum. Conclui-se que M. pruriens, pertencente à família Fabaceae, apresentou efeitos positivos nos processos de esporulação, enquanto P. glaucum, Poaceae, promoveu um ambiente mais propício para o desenvolvimento de uma comunidade de FMA mais diversificada.

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Johnson, Shelby, Hyun Park, Nicholas DaSilva, Dhiraj Vattem, Hang Ma, and Navindra Seeram. "Levodopa-Reduced Mucuna pruriens Seed Extract Shows Neuroprotective Effects against Parkinson’s Disease in Murine Microglia and Human Neuroblastoma Cells, Caenorhabditis elegans, and Drosophila melanogaster." Nutrients 10, no. 9 (August 22, 2018): 1139. http://dx.doi.org/10.3390/nu10091139.

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Mucuna pruriens (Mucuna) has been prescribed in Ayurveda for various brain ailments including ‘kampavata’ (tremors) or Parkinson’s disease (PD). While Mucuna is a well-known natural source of levodopa (L-dopa), published studies suggest that other bioactive compounds may also be responsible for its anti-PD effects. To investigate this hypothesis, an L-dopa reduced (<0.1%) M. pruriens seeds extract (MPE) was prepared and evaluated for its anti-PD effects in cellular (murine BV-2 microglia and human SH-SY5Y neuroblastoma cells), Caenorhabditis elegans, and Drosophila melanogaster models. In BV-2 cells, MPE (12.5–50 μg/mL) reduced hydrogen peroxide-induced cytotoxicity (15.7−18.6%), decreased reactive oxygen species production (29.1−61.6%), and lowered lipopolysaccharide (LPS)-induced nitric oxide species release by 8.9–60%. MPE (12.5−50 μg/mL) mitigated SH-SY5Y cell apoptosis by 6.9−40.0% in a non-contact co-culture assay with cell-free supernatants from LPS-treated BV-2 cells. MPE (12.5−50 μg/mL) reduced 6-hydroxydopamine (6-OHDA)-induced cell death of SH-SY5Y cells by 11.85–38.5%. Furthermore, MPE (12.5−50 μg/mL) increased median (25%) and maximum survival (47.8%) of C. elegans exposed to the dopaminergic neurotoxin, methyl-4-phenylpyridinium. MPE (40 μg/mL) ameliorated dopaminergic neurotoxin (6-OHDA and rotenone) induced precipitation of innate negative geotaxis behavior of D. melanogaster by 35.3 and 32.8%, respectively. Therefore, MPE contains bioactive compounds, beyond L-dopa, which may impart neuroprotective effects against PD.

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Phophi, Mutondwa M., Paramu L. Mafongoya, Alfred O. Odindo, and Lembe S. Magwaza. "Screening Cover Crops for Weed Suppression in Conservation Agriculture." Sustainable Agriculture Research 6, no. 4 (October 10, 2017): 124. http://dx.doi.org/10.5539/sar.v6n4p124.

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The use of herbicides amongst smallholder farmers is minimal because herbicides are expensive and they require specialized application equipments. Weeds are problematic in conservation agriculture where herbicides are expensive for smallholder farmers. The use of cover crops can help to suppress weed growth and development by creating an environment which is not suitable for weeds survival. Cowpea (Vigna unguiculata (L.) Walp) dolichos lablab (Lablab purpureus L.) and velvet bean (Mucuna pruriens (L.) DC) were evaluated for biomass accumulation and weed suppression under conservation agriculture system in two contrasting experimental sites: Ukulinga and Bergville in KwaZulu-Natal. Bare plot and herbicide treatments served as controls. Treatments were laid in a randomized complete block design, replicated three times. Mucuna pruriens (L.) DC had the highest biomass accumulation in both sites Bergville (0.72 t/ha) and Ukulinga (1.59 t/ha). Cowpea had the lowest biomass accumulation in Bergville (0.59 t/ha) and lablab was the lowest in Ukulinga (0.88 t/ha). Lablab was effective in suppressing weed biomass in Bergville (P < 0.05). Cowpea performed best in suppressing weed biomass in Ukulinga (P < 0.05). The results suggest that cowpea and lablab can be effective for weed suppression and therefore can be recommended for use in conservation agricultural systems.

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Winarni, Sri, and Yudhy Dharmawan. "The Processing Model in Making Tempeh Benguk [Mucuna pruriens (L.) DC] Containing High L-Dopa." KnE Life Sciences 3, no. 4 (March 27, 2017): 241. http://dx.doi.org/10.18502/kls.v3i4.711.

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“Koro benguk” [Mucuna pruriens (<a title="Carolus Linnaeus" href="https://id.wikipedia.org/wiki/Carolus_Linnaeus">L.</a>) <a title="A. P. de Candolle (halaman belum tersedia)" href="https://id.wikipedia.org/w/index.php?title=A._P._de_Candolle&action=edit&redlink=1">DC</a>] seed contains L-dopa which is able to repair spermatozoa quality. The aim of this experiment is to analyze L-Dopa using HPLC in engineering manufacture of tempeh benguk. There are four engineering model’s variants of making tempeh benguk. The engineering process begins with selection of koro benguk seed, tools required, immersion, boiling, humidity, temperature and pH. The result shows that the process in making tempeh benguk which contains the highest concentration of L-Dopa (11 346.85 mg · kg–1) is white-colored and intact koro benguk seed; one time immersion with replacing the water for 4 to 5 times/day (two days and two nights); one time boiling (< 1 h until koro benguk seed can be opened); mixed with 10 mL lime juice/1.5 kg, with concentration of 0.83 % until pH 5, added with mashed teak leaves, and ended with the process of making tempeh benguk at room temperature (30 ºC), relative humidity room (65 %). Tempeh benguk which is produced is cleaner, whiter, nonperishable, and more tender.<div>Keywords: HPLC; L-dopa; modified process of making; seeds benguk [Mucuna pruriens (<a title="Carolus Linnaeus" href="https://id.wikipedia.org/wiki/Carolus_Linnaeus">L.</a>) <a title="A. P. de Candolle (halaman belum tersedia)" href="https://id.wikipedia.org/w/index.php?title=A._P._de_Candolle&action=edit&redlink=1">DC</a>]; tempeh.</div>

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Nishihara, Eiji, Mohammad Masud Parvez, Hiroshi Araya, Shigeto Kawashima, and Yoshiharu Fujii. "L-3-(3,4-Dihydroxyphenyl)alanine (L-DOPA), an allelochemical exuded from velvetbean (Mucuna pruriens) roots." Plant Growth Regulation 45, no. 2 (February 2005): 113–20. http://dx.doi.org/10.1007/s10725-005-0610-x.

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Sanclemente Reyes, Óscar Eduardo, Carlos Omar Patiño Torres, and Liliana Rocío Beltrán Acevedo. "Análisis del balance energético de diferentes sistemas de manejo agroecológico del suelo, en el cultivo del maíz (Zea mays L.)." Revista de Investigación Agraria y Ambiental 3, no. 1 (May 15, 2012): 41. http://dx.doi.org/10.22490/21456453.929.

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En un suelo Typic Haplustalfs (USDA) del municipio de Palmira, Valle del Cauca (Colombia), se estableció el sistema de rotación fríjol terciopelo Mucuna pruriens Var. Utilis-maíz Zea mays L., en diseño de bloques completos al azar, con siete tratamientos y tres repeticiones. Los tratamientos en la rotación fueron: T1 (sin M. pruriens y sin fertilizar); T2 (abono verde de M. pruriens sin fertilizar); T3 (acolchado orgánico de M. pruriens sin fertilizar); T4 (abono verde de M. pruriens más abono orgánico compostado); T5 (abono verde de M. pruriens más fertilizante de síntesis química); T6 (abono verde de M. pruriens más abono orgánico compostado, complementado con fertilizante de síntesis química); T7 (acolchado orgánico de M. pruriens más abono orgánico compostado, complementado con fertilizante de síntesis química). Se caracterizaron el balance energético y el aporte nutricional usando software Energía 3.01, a partir de las entradas energéticas en cada tratamiento. Se obtuvo la mayor eficiencia energética en el T2 con 114,1, la cual fue significativamente mayor (p<0,05) que los demás tratamientos. El T5 donde se usó fertilización de síntesis química obtuvo un valor de 19,1, lo cual refleja altas entradas energéticas y baja productividad. Los mayores aportes nutricionales se obtuvieron en T3, T4, T6 y T7. Sin embargo, se destacan los tratamientos T3 y T4, en los que se usaron acolchado orgánico y abono verde de M. pruriens más compost, respectivamente, pues son tratamientos donde se hace un uso más eficiente de los recursos energéticos, por la utilización de insumos de fácil acceso para el productor; ello, a su vez, puede generar beneficios como alimentación para casi 50 personas.ha-1. año-1. Tales resultados sugieren esta asociación como alternativa valiosa para uso en la agricultura familiar campesina.

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Patoary, Raufun, Omar Ali Mondal, Ataur Rahman Khan, and Wahedul Islam. "Antibacterial activities of the seed extracts of some indigenous plants." Journal of Bangladesh Academy of Sciences 38, no. 2 (December 28, 2014): 119–25. http://dx.doi.org/10.3329/jbas.v38i2.21335.

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The chloroform and methanol extracts of seed and seed coat of Caesalpinia bonduc L., Mucuna pruriens L., Adenanthera pavonina L., Terminalia bellirica Geatn., Syzygium cumini L. and Myristica fragrans Houtt. were tested against 14 pathogenic bacteria. According to the intensity of activity against the selected bacteria the extracts could be arranged in a descending order of M. fragrans > A. pavonina > S. cumini > C. bonduc > M. pruriens > T. dbelerica. The minimum inhibitory concentrations (MIC) of the chloroform extract of seed of Syzygium cumini were 128 ?g/ml against Bacillus cereus and 64 ?g/ml against S. aureus. For the methanol extract the MIC values were 128 ?g/ml against B. cereus, Shigella dysenteriae and 64 ?g/ml against B. megaterium, S. aureus and S. sonnei. DOI: http://dx.doi.org/10.3329/jbas.v38i2.21335 Journal of Bangladesh Academy of Sciences, Vol. 38, No. 2, 119-125, 2014

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Mohapatra, Satyabrata, Partha Ganguly, Rahul Singh, and Chandra Kant Katiyar. "Estimation of Levodopa in the Unani Drug Mucuna pruriens Bak. and Its Marketed Formulation by High-Performance Thin-Layer Chromatographic Technique." Journal of AOAC INTERNATIONAL 103, no. 3 (May 2020): 678–83. http://dx.doi.org/10.5740/jaoacint.19-0288.

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Abstract Background: Mucuna pruriens Bak. Syn. Mucuna prurita Hook. seed is the rich source of levodopa (L-dopa) and has been used in traditional medicines to treat diseases resembling Parkinson’s disease. Objective: In the present study, a new HPTLC method was developed and validated for estimation of L-dopa from M. pruriens (black- and white-colored seeds) collected from two different locations in India. Method: TLC aluminum plates precoated with silica gel were used as the stationary phase. The plates were developed to a distance of 60 mm at a temperature of 22 ± 4°C in a twin glass chamber saturated with ethyl acetate–methanol–formic acid–water (15+3+3+4.5, v/v/v/v), as the mobile phase. Results: The Rf value of L-dopa was found to be 0.45. L-dopa was quantified at 282 nm, the wavelength of maximum absorbance by a densitometric scanner. The TLC plate was derivatized by ninhydrin reagent and photodocumented. L-dopa showed a good linearity in the concentration range 400–1000 ng/spot. The linear regression analysis of calibration plot showed good linear relationship between peak area and peak height (r2 = 0.997). Conclusions: The method was validated for precision, repeatability, and accuracy. Recovery was determined by spiking L-dopa with samples and was found to be 96.10%. Highlights: L-dopa was found to be present at concentration 3.02–4.72% in samples and its formulation.

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Chel-Guerrero, Luis, Saulo Galicia-Martínez, Juan José Acevedo-Fernández, Jesus Santaolalla-Tapia, and David Betancur-Ancona. "Evaluation of Hypotensive and Antihypertensive Effects of Velvet Bean (Mucuna pruriens L.) Hydrolysates." Journal of Medicinal Food 20, no. 1 (January 2017): 37–45. http://dx.doi.org/10.1089/jmf.2016.0080.

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WIDOWATI, WAHYU, HANA RATNAWATI, UDJU DJUNAEDI RUSDI, WAHYU WINARNO, and VICTOR IMMANUEL. "Phytochemicalassay and Antiplatelet Activity of Fractions of Velvet Bean Seeds (Mucuna pruriens L.)." HAYATI Journal of Biosciences 17, no. 2 (June 2010): 85–90. http://dx.doi.org/10.4308/hjb.17.2.85.

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Mahesh, S., and N. Sathyanarayana. "Intra-specific variability for salinity tolerance in Indian Mucuna pruriens L. (DC.) germplasm." Journal of Crop Science and Biotechnology 18, no. 3 (September 2015): 181–94. http://dx.doi.org/10.1007/s12892-015-0019-7.

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Kakwi, D. G., S. Awolumate, B. S. Audu, D. O. Oshinbajo, F. A. Oyedapo, M. Y. Mohammed, and K. M. Ositimehin. "Some aspects of histology of liver and intestine of Cyprinus carpio fingerlings fed raw and processed Mucuna pruriens diets." Nigerian Journal of Animal Production 48, no. 3 (March 6, 2021): 50–62. http://dx.doi.org/10.51791/njap.v48i3.2968.

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Mucuna contains anti-nutritional factors, anticoagulants, anti-inflammatory factors and L- dopa, a potentially neurotoxic agent. These anti-nutrients are endogenous toxic substances that are part of the normal feedstuff and affect its nutritional quality. The concentrations of these anti-nutritional factors can be reduced or completely eliminated if the seeds are properly processed. The impact of anti-nutritional factors and other toxic compounds in mucuna on fish have not been documented. Investigations on the dietary effects of raw and processed Mucuna pruriens seed diets on the histopatology of the liver and intestine of C. carpio fingerlings were carried out. The raw and the processed mucuna seed meals in two replacement levels of 20% and 50% as substitution of soybean meal in treatment diets were labelled Raw, MCD1 (20%) and MCD2 (50%), respectively, while a reference diet with no mucuna served as the control diet (CD). The diets were fed to C. carpio fingerlings (average weight, 15.40g) for 56 days. Water quality in the culture of C. carpio was was measured using standard procedure. Histopathological changes in the liver and intestine sections of fish were observed consistently and variable in the treatment groups. Water quality parameters were measured for the period of evaluation. Significant difference was not observed for all the water quality parameters measured. The water temperature varied between 22.90°C to 22.96oC similar to the room temperature. The pH ranged between 7.02 and 7.07 while dissolved oxygen ranged from 6.24 to 6.34 ppm. The liver of the fish fed raw mucuna diets showed vacoulation and severe necrosis of hepatocytes in the liver parenchyma and periportal areas. The histological analysis of the intestine of C. carpio fingerlings fed raw Mucuna diet also showed severe atrophy in the musculature of the intestinal villi of the fish which was mild in the fish fed MCD1 and control diets. The MCD1 was considered the most appropriate for dietary inclusion of Mucuna pruriens seeds in the feeding of C. carpio fingerlings. Mucuna contient des facteurs antinutrit nutritionnels, des anticoagulants, des facteurs anti- inflammatoires et de la L-dopa, un agent potentiellement neurotoxique. Ces antinutriments sont des substances toxiques endogènes qui font partie de l'aliment normal et affectent sa qualité nutritionnelle. Les concentrations de ces facteurs anti-nutritionnels peuvent être réduites ou complètement éliminées si les graines sont correctement traitées. L'impact des facteurs anti-nutritionnels et d'autres composés toxiques dans la mucuna sur les poissons n'a pas été documenté. Des études sur les effets diététiques des régimes crus et transformés de graine de Pruriens de Mucuna sur l'histopatologie du foie et de l'intestin des a ongles de C. carpio ont été effectuées. Les repas crus et transformés de graine de mucuna dans deux niveaux de remplacement de 20% et 50% comme remplacement de la farine de soja dans les régimes de traitement ont été étiquetés crus, MCD1 (20%) et MCD2 (50%), respectivement, tandis qu'un régime de référence sans mucuna a servi de régime de contrôle (CD). Les régimes ont été donnés aux acolings C. carpio (poids moyen, 15.40 g) pendant 56 jours. La qualité de l'eau dans la culture de C. carpiowas a été mesurée à l'aide d'une procédure standard. Des changements histopathologiques dans les sections hépatiques et intestinales des poissons ont été observés uniformément et variables dans les groupes de traitement. Des paramètres de qualité de l'eau ont été mesurés pour la période d'évaluation. Aucune différence significative n'a été observée pour tous les paramètres de qualité de l'eau mesurés. La température de l'eau variait entre 22.90 °C et 22.96 °C, semblable à la température ambiante. Le pH se situe entre 7.02 et 7.07 tandis que l'oxygène dissous varie de 6.24 à 6.34 ppm. Le foie des poissons alimentés régimes crus de mucuna a montré la vacoulation et la nécrose grave des hépatocytes dans le parenchyme de foie et les secteurs periportal. L'analyse histologique de l'intestin des ails de C. carpio alimentés au régime cru de Mucuna a également montré l'atrophie grave dans la musculature des villosités intestinales du poisson qui était douce dans les poissons alimentés MCD1 et les régimes de contrôle. Le MCD1 a été considéré comme le plus approprié pour l'inclusion diététique des graines pruriens de Mucuna dans l'alimentation des acolings de C. carpio.

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Leelambika, M., S. Mahesh, M. Jaheer, P. K. Tripathi, P. Ranjith Kumar, and N. Sathyanarayana. "Targeted Metabolic and Genomic Profiling Reveals Parents for L-Dopa Breeding in Mucuna pruriens (L.) DC." Tropical Plant Biology 9, no. 4 (June 8, 2016): 239–51. http://dx.doi.org/10.1007/s12042-016-9174-3.

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Chinapolaiah, A., Hima Bindu K., Manjesh G.N., V. Thondaiman, V. Keshava Rao, Hariprasad Rao N., and Sudheer Kumar S. "Variability in L-Dopa and other biochemical composition of Mucuna pruriens (L.) an underutilized tropical legume." Industrial Crops and Products 138 (October 2019): 111447. http://dx.doi.org/10.1016/j.indcrop.2019.06.010.

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Parmezan, Sheila Negrini, Lílian Klein, Brás Heleno Oliveira, Fernanda Bovo, and Elisa Perez. "Otimização do método extração de compostos fenólicos totais em sementes de Mucuna pruriens (L.) D.C." Revista de Ciências Médicas e Biológicas 16, no. 1 (July 14, 2017): 34. http://dx.doi.org/10.9771/cmbio.v16i1.13501.

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Plantas do gênero Mucuna são usadas para o tratamento do Mal de Parkinson em muitos países. Estas ações farmacológicas são associadas à presença de levodopa e de compostos fenólicos, que auxiliam no potencial antioxidante da droga. O objetivo desse trabalho foi otimizar um método eficiente para o preparo de amostra a fim de quantificar a concentração de fenólicos totais (TP) em três variedades de sementes de M. pruriens pelo método de Folin-Denis. Sementes de três variedades de M. pruriens L. foram usadas. Foi utilizado planejamento fatorial 24 com ponto central (n=3) e as variáveis foram: tipo do líquido extrator; presença de HCl ou ausência; tipo de extração e tempo de extração. O preparo de amostra otimizado resultou em extração com água acidificada com HCl 1,14 M em vórtex por 5 min. O teor de TP foi 2,971 ± 0,143 mg de ácido 3-hidroxicinâmico (3-HC) % (var. cinza), 2,916 ± 0,093mg 3-HC % (var. preta) e 2,588 ± 0,120 mg 3-HC % (var. verde) em relação ao pó da semente.

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Santos Ricalde, Ronald Herve, Luis Sarmiento Franco, Francisco Lopez Santiz, and Carlos Sandoval Castro. "Mucuna pruriens seeds given in broiler diets on growth performance and carcass yield." Ecosistemas y Recursos Agropecuarios 6, no. 16 (January 1, 2019): 121. http://dx.doi.org/10.19136/era.a6n16.1815.

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The aim of this study was to evaluated the effect of soaked Mucuna pruriens (MP) seeds in tap water, acid or alkaline solution + cooking on its L-Dopa content and on the productive performance of broiler chickens. Ninety-six sexed chicks aged 21-days old with an initial live weight of 720 ± 80 g were used. Four diets were used, a control without MP (C) and three diets including 25 % MP: a) soaked MP in tap water + cooking (WMP); b) soaked MP in acetic acid solution + cooking (AAMP); c) soaked MP in calcium hydroxide solution + cooking (CHMP). The alkaline treatment reduced 71 % of L-Dopa in comparison to acid or water treatment (53 % and 41 % respectively). In the starter phase, the acid group had the lowest live weight gain (p<0.05) and highest feed conversion ratio when compared to control (p<0.05). Productive performance of birds fed with CHMP and C group was similar (p>0.05). In the finisher phase, there was not statistical difference in feed intake, live weight gain and feed conversion ratio among treatments (p>0.05). No differences were observed in carcass yield (p>0.05), but, the birds fed MP or AAMP had a heavier liver than birds on C group (p<0.05). Results shown that 25 % of CHMP can be used as feedstuff for broiler chickens without negative effects in their productive performance. Keywords: Velvet bean, L-Dopa, Poultry, weight gain.

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Singh, Susheel Kumar, and Sunita Singh Dhawan. "Analyzing trichomes and spatio-temporal expression of a cysteine protease gene Mucunain in Mucuna pruriens L. (DC)." Protoplasma 255, no. 2 (October 3, 2017): 575–84. http://dx.doi.org/10.1007/s00709-017-1164-2.

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Journal articles on the topic 'Mucuna pruriens (L.)'

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