Journal articles: 'Mucuna pruriens'

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Susilowati, Indah Tri, and Purwati Purwati. "The Measurement of Antioxidant Activity of Velvet Beans (Mucuna pruriens) and Velvet Beans (Mucuna pruriens) in Coffee Preparations." Biomedika 13, no. 2 (February 28, 2021): 117–22. http://dx.doi.org/10.31001/biomedika.v13i2.900.

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Antioxidant activity tests of methanol extracts of velvet beans (Mucuna pruriens) and velvet beans (Mucuna pruriens) in coffee preparations have been previously carried out by several researchers. This present study aims to examine the phytochemical and antioxidant activities of methanol extracts of Mucuna pruriens and Mucuna pruriens in coffee preparations. The methanol extract was tested for the phytochemical and antioxidant activities by applying DPPH (1,1-Dhiphenyl-2-picrylhydrazil) method. The results of the phytochemical test showed that the methanol extracts of the Mucuna pruriens and Mucuna pruriens in coffee preparations contained secondary metabolites of flavonoids, alkaloids, saponins, terpenoids, and tannins. The outcomes of the antioxidant activity test revealed that the methanol extracts of the Mucuna pruriens and Mucuna pruriens in coffee preparations had antioxidant activities, as indicated by the IC50 values of 42.09 ppm and 37.23 ppm. It was also revealed that the antioxidant content of Mucuna pruriens in coffee preparations was stronger than the content in the velvet beans alone.

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GopiKrishna Rakam and Raja Sundararajan. "In vitro antioxidant activity of Bougainvillea glabra and Mucuna pruriens." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (January 25, 2020): 806–12. http://dx.doi.org/10.26452/ijrps.v11i1.1898.

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The purpose of the contemporary in vitro work implemented was to examine the antioxidant effect of Bougainvillea glabra and Mucuna pruriens methanol extracts. Methanol extracts of Bougainvillea glabra and Mucuna pruriens were screened individually for different in vitro antioxidant activity. Commercial antioxidants such as vitamin E, Ascorbic acid were used as reference standard. For ABTS+ assay IC50 value of Bougainvillea glabra & Mucuna pruriens methanol extract were found to be 17.1μg/ml and 23.2μg/ml correspondingly. Likewise, the IC50 values for xanthine oxidase inhibitory activity for Bougainvillea glabra and Mucuna pruriens was found to be 46.7μg/ml and 95.1μg/ml, respectively. For scavenging of various assay models like nitric oxide, hydroxyl and superoxide anion scavenging activity, the IC50 values for Bougainvillea glabra were found to be 45.3μg/ml, 70.1μg/ml and 38.1μg/ml respectively. The IC50 values for Mucuna pruriens for nitric oxide, hydroxyl and superoxide anion scavenging activity, were found to be 92.1μg/ml, 43.4μg/ml and 50.3μg/ml respectively. Bougainvillea glabra and Mucuna pruriens methanol extracts showed 50 % inhibition effect at concentrations 118 μg/ml and 121 μg/ml respectively for lipid peroxidation assay. The IC50 values for DPPH scavenging assay for Bougainvillea glabra and Mucuna pruriens was found to be 13.24μg/ml and 14.4μg/ml correspondingly. For DMPD assay Bougainvillea glabra and Mucuna pruriens possess the IC50 value 16.34 μg/ml and 17.4 μg/ml correspondingly. Methanol extracts of Bougainvillea glabra and Mucuna pruriens exhibited potent in vitro antioxidant activity.

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Singh, Shobhit, Pushpraj Gupta, and Rishikesh Gupta. "Evaluation of anti-anxiety activity of Mucuna pruriens." Journal of Drug Delivery and Therapeutics 9, no. 4-A (August 30, 2019): 104–7. http://dx.doi.org/10.22270/jddt.v9i4-a.3420.

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Mucuna pruriens, also known as Velvet Bean, Mucuna pruriens has been used for centuries by Ayurvedic herbalists for overall wellness. Mucuna pruriens provides support for brain function, muscle health and libido. Mucuna pruriens has also been shown to have diuretic effects. It increases tissue resiliency and improves coordination. Mucuna can also increase testosterone levels, which in turn can lead to increased muscle mass and strength. It also supports the nervous and reproductive systems in the body. anti-oxidant activity of M. pruriens has been also demonstrated in vitro by its ability to scavenge DPPH radicals and reactive oxygen species. This is an excellent natural source of L-dopa and 5-hydroxy tryptophan (5-HT) Present study was designed to evaluate the anti-anxiety activity of Mucuna pruriens extract in Swiss albino mice. Three doses of Mucuna pruriens (100, 200,400 mg/kg, p.o.) and standard dose of Buspirone (5 mg/kg, i.p.) were used for evaluation of the anti-anxiety activity. The elevated plus maze (EPM) was used to take as a measure of antianxiety effect. Mucuna pruriens at the doses of 200 mg/kg and 400 mg/kg significantly reduced the time spent and no. of entries in closed arm, increased the time spent and entries into open arm in elevated plus maze (p<0.05) as compared to control group. These results indicate that MP may be possesses antianxiety property. Keywords: Anxiety, Elevated plus maze, Mucuna pruriens, Buspirone, Swiss Albino Mice.

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Appiah, Kwame, Christiana Amoatey, and Yoshiharu Fujii. "Allelopathic activities of selected Mucuna pruriens on the germination and initial growth of lettuce." International Journal of Basic and Applied Sciences 4, no. 4 (November 27, 2015): 475. http://dx.doi.org/10.14419/ijbas.v4i4.5148.

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The study was conducted to test allelopathic effects of some Mucuna pruriens on the germination and growth of lettuce. The effects of root exudates and leaf leachates of eight mucuna genotypes; Mucuna pruriens var. utilis cv. cinza, Mucuna pruriens var. utilis cv. preta, Mucuna pruriens var. utilis cv. hassjo, Mucuna pruriens var. utilis cv. fvb, Mucuna pruriens 82/507, Mucuna pruriens 82/508, Mucuna pruriens 82/116, and Mucuna pruriens GA/94/002 were tested on the germination, radicle, and hypocotyl elongations of lettuce (Lactuca sativa var. Great Lakes 366). The effects of leaf leachates and root exudates of mucuna were tested using sandwich and plant-box methods respectively with lettuce as the receptor plant. Roots exudates inhibition varied significantly among genotypes (94.3%-98.5%). Root exudates of Mucuna pruriens var. utilis cv. fvb had the maximum inhibition (98.5%). Lettuce radicle inhibition gradually decreased with distance from the mucuna plant in a plant-box and with high correlation (r=0.910-0.952; p<0.05) between lettuce radicle inhibition and distance from mucuna roots. The effect of 50 mg oven-dried mucuna leaves had significant inhibition on lettuce radicle elongation (12.0%-15.8% of untreated control). Leaf leachates had less effect on the hypocotyl elongation of lettuce (50.5%-72.0% of untreated control) at the same application of oven-dried leaves (50 mg/10 ml agar).

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KRISHNARAJ, MOOTHEDATHU VENUGOPALAN NAIR, and NARAYANAN NAIR MOHANAN. "Notes on the identity and status of two Legumes (Fabaceae: Papilionoideae) from India." Phytotaxa 66, no. 1 (September 11, 2012): 13. http://dx.doi.org/10.11646/phytotaxa.66.1.3.

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Umiyati, Uum. "Allelopathic Inhibition of Nitrifying Bacteria by Legumes." Journal of Tropical Soils 22, no. 2 (May 1, 2017): 125–30. http://dx.doi.org/10.5400/jts.2017.v22i2.125-130.

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The study aimed at understanding the competitive ability of legumes Vigna radiata L. and Mucuna pruriens with weeds and their effects on the activity of nitrifying bacteria in soils and the contents of organic-N in legumes and weeds. The experiment was arranged in a randomized block design with three factors and four replications. The first factor was soil order, i.e. Inceptisol and Vertisol; the second factor was types of legumes, i.e. Vigna radiata L. cultivar Sriti and Mucuna pruriens; and the third factor was weed management, i.e. with weed management and without weed management. The results showed that Vigna radiata L. and Mucuna pruriens indirectly influence the supply of available nitrogen in soils that can be taken up by the coexisted plants or weeds via the inhibition of the growth of Nitrosomonas and Nitrobacter in soils. As a results, the organic-N content in weeds decreases, which is in contrast to the increasing amount of organic-N in Vigna radiata L. and Mucuna pruriens. The results indicated that Vigna radiata L. and Mucuna pruriens are considered as allelophatic legumes, resulting in low organic-N content in weeds. Keywords: Allelopathic, Mucuna pruriens, Nitrosomonas, Nitrobacter, Vigna radiata

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Chattopadhyay, Sharmila, S. K. Datta, and S. B. Mahato. "Rapid micropropagation for Mucuna pruriens f. pruriens L." Plant Cell Reports 15, no. 3-4 (December 1995): 271–73. http://dx.doi.org/10.1007/bf00193734.

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Prías, Leila, Vicente Painii, Alfonso Ramos, Oswaldo Pesantes, Ana Zambrano, Andrea Vargas, Fabricio Tamayo, and Leonardo Vargas. "Mucuna pruriens, alternativa contra la desnutrición." Investigación, Tecnología e Innovación 1, no. 1 (November 30, 2009): 129–50. http://dx.doi.org/10.53591/iti.v1i1.32.

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El presente artículo investiga la factibilidad de utilización de la leguminosa silvestre Mucuna pruriens (L.) DC. (fabáceae) como una alternativa viable para paliar el déficit nutricional que presenta un amplio porcentaje de niños y niñas que se educan en las escuelas de Guayaquil. Se considera que el bajo rendimiento escolar que se observa en la educación fiscal, está relacionado con la deficiente alimentación de los educandos. Para el efecto, se analizó el valor biológico del frejol Mucuna Pruriens8• Se prepararon y presentaron varios productos hechos a partir de esta leguminosa9, se recolectaron semillas en Vinces para culturizarlas, y con ellas se realizaron los estudios de este trabajo en las Facultades de Ciencias Químicas, Ingeniería Química e ITAV de la Universidad de Guayaquil. Se determinó que el fréjol M. Pruriens no presenta toxicidad aguda oral, tiene un alto valor nutricional al poseer proteínas de buena calidad, aminoácidos esenciales, vitaminas, entre otros. Su nivel de digestibilidad se determinó en el 91,81 %, manteniendo las proteínas después de la cocción. Se evaluó su impacto positivo en la salud de los educandos de una escuela de Guayaquil, comprobándose un aume nto significativo de las proteínas séricas y nivel de madurez en la percepción viso-motriz y desarrollo mental. Con respecto a su factibilidad económica, se determinó una eficiente relación costo/beneficio.

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Sardjono, Ratnaningsih Eko, Iqbal Musthapa, Sholihin ., Atun Qowiyah, and Rahmi Rachmawati. "ACUTE TOXICITY EVALUATION OF ETHANOL EXTRACT OF INDONESIAN VELVET BEANS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 5 (May 1, 2017): 161. http://dx.doi.org/10.22159/ijpps.2017v9i5.16284.

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Objective: This research was conducted to determine the acute toxicity of ethanol extract of velvet beans (Mucuna pruriens) from Indonesia. Extract of Indonesian Mucuna pruriens seeds showed antiparkinson activity due to the presence of L-DOPA inadequate levels. However, research on the toxicity level of Mucuna pruriens seeds from Indonesia is still limited. Acute toxicity data are needed to make Mucuna pruriens as standardized herbal medicine for Parkinson disease.Methods: The dried seed of Mucuna pruriens was extracted by ethanol and suspended with tragacanth to make several dosas of ethanol extract of Mucuna pruriens seeds. Determination of acute toxicity was performed on six groups, each consisting of five Wistar rats. One group was used as a control group; other groups were given ethanol extract of Mucuna pruriens seeds orally at a dose of 5 mg/kg, 50 mg/kg, 300 mg/kg, 2000 mg/kg, and 5000 mg/kg body weight. Symptoms of toxicity, including death, were observed daily for 14 d. At the end of the observation, the surviving Wistar rats were autopsied and the brain, heart, liver, lungs, stomach, spleen, kidneys, and ovaries were weighed to give relative organ weight.Results: There was no mortality observed in all groups. The Wistar rats gained weight within the normal range. The relative organ weights in all groups generally did not show a significant difference. However, the significant differences (P<0.05) were seen in the liver for all treatment groups compared to the control group.Conclusion: The ethanol extract of Mucuna pruriens seeds from Indonesia administered orally has LD50>5000 mg/kg, thus it could be regarded as safe or non-toxic. However, this extract may be potentially toxic to the liver

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Harini, S. S., and Sathyanarayana N. "Somatic embryogenesis in Mucuna pruriens." African Journal of Biotechnology 8, no. 22 (November 16, 2009): 6175–80. http://dx.doi.org/10.5897/ajb09.815.

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Contin, Manuela, Giovanna Lopane, Andrea Passini, Ferruccio Poli, Carmelina Iannello, and Maria Guarino. "Mucuna pruriens in Parkinson Disease." Clinical Neuropharmacology 38, no. 5 (2015): 201–3. http://dx.doi.org/10.1097/wnf.0000000000000098.

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Hairiah, Kurniatun, Meine van Noordwijk, Ineke Stulen, and Pieter J. C. Kuiper. "Aluminium avoidance by Mucuna pruriens." Physiologia Plantarum 86, no. 1 (September 1992): 17–24. http://dx.doi.org/10.1034/j.1399-3054.1992.860103.x.

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Cilia, Roberto, Janeth Laguna, Erica Cassani, Emanuele Cereda, Nicolò G. Pozzi, Ioannis U. Isaias, Manuela Contin, Michela Barichella, and Gianni Pezzoli. "Mucuna pruriens in Parkinson disease." Neurology 89, no. 5 (July 5, 2017): 432–38. http://dx.doi.org/10.1212/wnl.0000000000004175.

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Objective:To investigate whether Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in all tropical areas worldwide, may be used as alternative source of levodopa for indigent individuals with Parkinson disease (PD) who cannot afford long-term therapy with marketed levodopa preparations.Methods:We investigated efficacy and safety of single-dose intake of MP powder from roasted seeds obtained without any pharmacologic processing. Eighteen patients with advanced PD received the following treatments, whose sequence was randomized: (1) dispersible levodopa at 3.5 mg/kg combined with the dopa-decarboxylase inhibitor benserazide (LD+DDCI; the reference treatment); (2) high-dose MP (MP-Hd; 17.5 mg/kg); (3) low-dose MP (MP-Ld; 12.5 mg/kg); (4) pharmaceutical preparation of LD without DDCI (LD−DDCI; 17.5 mg/kg); (5) MP plus benserazide (MP+DDCI; 3.5 mg/kg); (6) placebo. Efficacy outcomes were the change in motor response at 90 and 180 minutes and the duration of on state. Safety measures included any adverse event (AE), changes in blood pressure and heart rate, and the severity of dyskinesias.Results:When compared to LD+DDCI, MP-Ld showed similar motor response with fewer dyskinesias and AEs, while MP-Hd induced greater motor improvement at 90 and 180 minutes, longer ON duration, and fewer dyskinesias. MP-Hd induced less AEs than LD+DDCI and LD−DDCI. No differences in cardiovascular response were recorded.Conclusion:Single-dose MP intake met all noninferiority efficacy and safety outcome measures in comparison to dispersible levodopa/benserazide. Clinical effects of high-dose MP were similar to levodopa alone at the same dose, with a more favorable tolerability profile.ClinicalTrials.gov identifier:NCT02680977.

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Hairiah, Kurniatun, Meine Noordwijk, Ineke Stulen, and Pieter J. C. Kuiper. "Aluminium avoidance by Mucuna pruriens." Physiologia Plantarum 86, no. 1 (September 1992): 17–24. http://dx.doi.org/10.1111/j.1399-3054.1992.tb01306.x.

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Chikagwa-Malunga, S. K., A. T. Adesogan, L. E. Sollenberger, S. C. Phatak, N. J. Szabo, S. C. Kim, C. M. Huisden, and R. C. Littell. "Nutritional characterization of Mucuna pruriens." Animal Feed Science and Technology 148, no. 2-4 (January 2009): 124–37. http://dx.doi.org/10.1016/j.anifeedsci.2008.03.003.

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Chikagwa-Malunga, S. K., A. T. Adesogan, L. E. Sollenberger, L. K. Badinga, N. J. Szabo, and R. C. Littell. "Nutritional characterization of Mucuna pruriens." Animal Feed Science and Technology 148, no. 1 (January 2009): 34–50. http://dx.doi.org/10.1016/j.anifeedsci.2008.03.004.

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Chikagwa-Malunga, S. K., A. T. Adesogan, N. J. Szabo, R. C. Littell, S. C. Phatak, S. C. Kim, K. G. Arriola, C. M. Huisden, D. B. Dean, and N. A. Krueger. "Nutritional characterization of Mucuna pruriens." Animal Feed Science and Technology 148, no. 2-4 (January 2009): 107–23. http://dx.doi.org/10.1016/j.anifeedsci.2008.03.006.

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Naman, Kasang, Habibat Oseni, and Emmanuel Enoh. "ANTI-ANAEMIC POTENTIAL OF METHANOLIC LEAF EXTRACT OF MUCUNA PRURIENS ON PHENYLHYDRAZINE (PHZ) INDUCED ANAEMIC ALBINO WISTAR RATS." FUDMA JOURNAL OF SCIENCES 4, no. 3 (September 24, 2020): 370–74. http://dx.doi.org/10.33003/fjs-2020-0403-399.

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The antianaemic potential of methanolic leaf extracts of Mucuna pruriens was investigated using phenylhydrazine (PHZ) induced anaemic albino Wistar rats. Fifteen rats used for the study were randomized into five experimental groups. To induced anaemia, the rats (except the normal control, Group E), received 60 mg/kg of the haemolytic agent Phenylhydrazine intraperitoneally (i.p) for two consecutive days. Anaemic Wistar rats in groups A and B received a daily oral dose of 500 and 250 mg/kg of the methanolic leaf extract of Mucuna pruriens. Nweze et al. (2016) had reported a median lethal dose greater than 5000 mg/kg for the methanol leaf extract of Mucuna pruriens. Groups C and D received Vitamin B12 (10 mg/kg) and normal saline (1 ml/kg), respectively. Normal control rats also received normal saline (1 ml/kg). Extract or normal saline was administered per os (p.o) while vitamin B12 was administered i.p. for a duration of 21 days. Packed cell volume (PCV) and haemoglobin concentration were determined weekly for three weeks. The result of the study indicated that both the methanolic leaf extract of Mucuna pruriens and Vitamin B12 significantly (p < 0.05) increased the packed cell volume and haemoglobin concentrations in treated rats compared to the negative control group of rats. This indicated that the methanolic leaf extract of Mucuna pruriens has anti-anaemic properties and could be utilized in the management of anaemia

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Misra, Laxminarain, and Hildebert Wagner. "Alkaloidal constituents of Mucuna pruriens seeds." Phytochemistry 65, no. 18 (September 2004): 2565–67. http://dx.doi.org/10.1016/j.phytochem.2004.08.045.

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Bature, M. S., A. H. Hassan, H. J. Jantar, and A. S. Shu’aibu. "Effect of fertilizer levels and plant spacing on the performance of Mucuna prureins (velvet bean) in the Northern Guinea Savanna of Nigeria." Bayero Journal of Pure and Applied Sciences 11, no. 1 (October 11, 2018): 57–60. http://dx.doi.org/10.4314/bajopas.v11i1.11.

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Fertilizer recommendation for crop and plant spacing is dynamic process in view of the generation of new knowledge with management practices. Information such as (phosphorus levels and plant spacing) on maintaining adequate soil fertility is very much important for producing better forages for livestock. Leguminous crop such as Velvet bean (Mucuna pruriens) can alleviate some of these problems. Field experiment was conducted to access the effect of phosphorus fertilizer application level at 0, 80 and 120kg/ha and plant spacing interval of 30, 60 and 90cm of Velvet bean. Application of 80kg/ha of phosphorus fertilizer significantly influenced the performance of Mucuna plant such as plant height, number of branches and forage yield. Plant spacing interval of 30cm resulted in better stand count, taller plant, higher number of branches and forage yield per plant. Famers in Northern Guinea Savanna of Nigeria can adopt the application of phosphorus fertilizer at 80kg/ha and using narrower spacing (25cm by 30cm) for better yield of Mucana, thereby increasing farm output and animal performance.Keywords: phosphorus level, plant spacing, Mucuna pruriens, Velvet bean

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Lima, Andréa Aparecida de, Paulo Ivan Fernandes Júnior, Samuel Ribeiro Passos, Fernanda Santana de Paulo, Sumaya Mário Nosoline, Sérgio Miana de Faria, José Guilherme Marinho Guerra, Norma Gouvêa Rumjanek, and Gustavo Ribeiro Xavier. "Diversidade e capacidade simbiótica de rizóbios isolados de nódulos de Mucuna-Cinza e Mucuna-Anã." Revista Brasileira de Ciência do Solo 36, no. 2 (April 2012): 337–48. http://dx.doi.org/10.1590/s0100-06832012000200003.

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As espécies de mucuna são muito utilizadas como adubos verdes, e poucas informações estão disponíveis a respeito dos rizóbios nativos capazes de nodulá-las. O objetivo deste trabalho foi avaliar a diversidade e a capacidade simbiótica de isolados bacterianos de nódulos de mucuna-cinza (Mucuna pruriens (L.) DC.) e mucuna-anã (Mucuna deeringiana (Bort.) Merr.). As bactérias foram isoladas de nódulos de mucunas cinza e anã cultivadas em vasos com solos de um sistema de produção agroecológica. Foram isoladas 160 bactérias, sendo 80 de mucuna-anã e 80 de mucuna-cinza, que foram autenticadas e selecionadas para avaliação da capacidade simbiótica. A diversidade dos isolados foi avaliada por meio das características culturais em meio de cultura YMA e da técnica de análise de restrição do produto de PCR do gene 16S rDNA. A inoculação de cinco isolados em mucuna-cinza e dois em mucuna-anã apresentou elevada biomassa da parte aérea. A maioria dos isolados apresentou crescimento rápido e acidificou o meio de cultura. A análise de restrição demonstrou que as bactérias isoladas apresentam baixa similaridade com estirpes de referência, sugerindo a existência de isolados pertencentes a novos grupos, capazes de nodular as mucunas anã e cinza.

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Kavitha, C., and C. Thangamani. "Amazing bean Mucuna pruriens: A comprehensive review." Journal of Medicinal Plants Research 8, no. 2 (January 10, 2014): 138–43. http://dx.doi.org/10.5897/jmpr2013.5036.

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Iauk, L., E. M. Galati, S. Kirjavainen, A. M. Forestieri, and A. Trovato. "Analgesic and Antipyretic Effects of Mucuna Pruriens." International Journal of Pharmacognosy 31, no. 3 (January 1993): 213–16. http://dx.doi.org/10.3109/13880209309082944.

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Vaish, Supriya, S. Choudhary, Nafroz Khosla, Sachin Sharma, JaiMeher Singh, and S. Sudarsanan. "Mucuna pruriens (Konch Beej) precipitates manic symptoms." Journal of Mental Health and Human Behaviour 19, no. 2 (2014): 85. http://dx.doi.org/10.4103/0971-8990.153717.

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Lampariello, Lucia Raffaella, Alessio Cortelazzo, Roberto Guerranti, Claudia Sticozzi, and Giuseppe Valacchi. "The Magic Velvet Bean of Mucuna pruriens." Journal of Traditional and Complementary Medicine 2, no. 4 (October 2012): 331–39. http://dx.doi.org/10.1016/s2225-4110(16)30119-5.

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Leite Tavares, Renata, Maria da Conceição Rodrigues Gonçalves, Jailane de Souza Aquino, Raquel Suelen Brito da Silva, and Alexandre Sérgio Silva. "Androgenic and Anabolic Possibilities of Mucuna Pruriens." Journal of Food and Nutrition Research 5, no. 12 (December 1, 2017): 925–27. http://dx.doi.org/10.12691/jfnr-5-12-7.

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Anand, Sanjay. "Evaluation of nutrient uptake of selected cover crops and biochar on the yield advantage of two taro (Colocasia esculenta) cultivars in Samoa." South Pacific Journal of Natural and Applied Sciences 36, no. 1 (2018): 9. http://dx.doi.org/10.1071/sp18002.

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A study was conducted in three agro ecological zones of Samoa to compare the dry matter yields and nutrient uptake of selected tropical cover crops and biochar application on different Samoan inceptisols. Subsequent improvements in corm yield of the two taro cultivars, (Samoa 1 and Samoa 2), under these fallow systems were also determined. The split-plot arrangement with main plots as cover crops and subplots as the cultivars was used, with four replications. The evaluated cover crops included: a reference – grass fallow treatment (farmers practice), Mucuna pruriens, Erythrina subumbrans, Mucuna pruriens + 200 kg of NPK fertiliser (12-5-20), farmer’s reference practice + 400 kg of NPK fertiliser (12-5-20), and biochar produced from coconut shells. The biomass samples were collected after the six month of fallow duration. Plant tissue analyses revealed that the nitrogen and the phosphorus contents of erythrina was higher than corresponding mucuna cover across all three sites. However, as a result of higher biomass production, Mucuna pruriens showed the highest nutrient accrual over the six month fallow duration. The general yield trend under different fallow practices across all the sites indicates that mucuna with modest supplementation of complete fertilisers can help maintain optimum taro yields. However, it appears that the yield responses of the taro crop to fallow treatments are site-specific.

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Panova, A. S., D. S. Dergachev, M. A. Subotyalov, and V. D. Dergachev. "Review of Mucuna pruriens L. therapeutic potential for Parkinson’s disease." Meditsinskiy sovet = Medical Council, no. 8 (July 16, 2020): 82–87. http://dx.doi.org/10.21518/2079-701x-2020-8-82-87.

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Parkinson’s disease is a multifactorial disorder of the nervous system, the main features of which are progressive degeneration of dopaminergic neurons in the nigra pars compacta nigrostriatal tract and subsequent deficiency of the neurotransmitter dopamine in the areas of the brain, leading to the loss of motor function, the emergence of non-motor symptoms, rigidity, akinesia or bradykinesia, motor block, and decline in cognitive functions. Parkinson’s disease has high prevalence throughout the world, and has no curative treatment in modern medicine. The available drugs such as anticholinergics, levodopa and a DOPA-decarboxylase inhibitor provide symptomatic relief only. Although dopaminergic therapy is the standard treatment of motor disabilities associated with Parkinson’s disease, it does not managed all the aspects of the disease. For this reason, the increasing numbers of patients are looking for more holistic approach to the treatment of this disease. Mucuna pruriens L. – an annual self-pollinating legume plant, can be considered as a potential complementary therapy for patients with Parkinson’s disease, as it is an extremely rich source of levodopa. Numerous studies have shown that Mucuna pruriens extracts restore biochemical and behavioral abnormalities in animals with the experimental model of Parkinson’s disease. The plant also demonstrates some antioxidant activity. The clinical effects of high-dose Mucuna pruriens are similar to levodopa, but have a more favorable tolerance profile. If long-term use of Mucuna pruriens proves safe and effective in controlled clinical trials, it could become a sustainable complementary therapy for the treatment of Parkinson’s disease, especially in low-income countries.

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Milla, Meidona Nurul, Yani Istadi, Vania Shaula, Deastri Anjeas Wari, Chntyia Dwi Cahyani Puspitasari, and Umar Usman Bin Sef. "The Potential Effect of Mucuna pruriens Seed Extract on Sperm Quality experimental study on mice exposed to cigarette smoke." Bangladesh Journal of Medical Science 20, no. 4 (June 18, 2021): 768–73. http://dx.doi.org/10.3329/bjms.v20i4.54132.

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Background: Infertility has been more common problems among couple of reproductive age. One of the factors causing this disorder is unhealthy environmental factors including exposure to cigarette smoke. Polynuclear aromatic hydrocarbons (PAHs) in cigarette smoke can cause testicular atrophy, while the free radicals can inhibit the stages of spermatogenesis, and nicotine in cigarettes affects the brain dopamine levels affecting the levels of GnRH, and subsequently affect the levels of FSH and LH needed in spermatogenesis. The use of Mucuna pruriens seed extract containing antioxidants and L-dopa is expected to improve the quality of sperm after exposure to cigarette smoke. Objective: This study aimed to determine the effect of Mucuna pruriens seed extract on the sperm quality in mice exposed to cigarette smoke. Methods: This study was an experimental study with a post test only control group design. A total of 20 mice were divided into 4 groups of five mice each. All groups were exposed to cigarette smoke. Group 1 was the negative control exposed to cigarette smoke. Groups 2, 3, 4 were exposed to cigarettes smoke and given Mucuna pruriens seed extracts at the dose of 250; 300; and 350 mg/Kg BW/day. Parameters of sperm quality included concentration, morphology, motility and viability. Results: Post hoc tests showed there were significant differences among treatment groups. Conclusion: the administration of Mucuna pruriens seed extract affects the sperm quality of BALB/c mice exposed to cigarettes smoke. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.768-773

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Traore, Sidi Oumar, Alassane Ba, Doubangolo Coulibaly, Abdoul Kader Kone, Bouréma Kone, and Nangboro Ferdinand Dembele. "Production du fourrage de Mucuna pruriens pour l’alimentation des animaux et sa marge brute en zone cotonnière du Mali." International Journal of Biological and Chemical Sciences 15, no. 1 (April 21, 2021): 117–28. http://dx.doi.org/10.4314/ijbcs.v15i1.11.

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En zone cotonnière du Mali, la situation d’affouragement des animaux est largement déficitaire. Pour améliorer la disponibilité des ressources fourragères, la recherche en partenariat avec les producteurs a introduit en milieu paysan la culture de Mucuna pruriens. Cette étude vise à évaluer les performances de M. pruriens dans la production du fourrage pour les animaux. Les essais ont été conduits par 25 producteurs répartis dans 5 sites durant les campagnes agricoles 2015-2016, 2016-2017 et 2017-2018. Les essais étaient divisés en deux parcelles tests : culture pure de M. pruriens et association M. pruriens/maïs. La production moyenne en biomasse de M. pruriens pur sur les 3 campagnes agricoles a été de 4 363±1 491kg MS/ha. Cette production couvre les besoins en matière sèche de 7,76±2,65 UBT durant 90 jours. Pour l’association, la production de biomasse a été de 5 449±1 766 kg MS/ha, elle couvre les besoins en matière sèche de 9,69±3,14 UBT pendant 90 jours. La marge brute de la culture pure de M. pruriens est de 786 060±298 140 FCFA/ha. Pour l’association, elle est de 850 917±36 1887 FCFA/ha. La culture de M. pruriens favorise l’intégration agriculture-élevage tout en améliorant l’alimentation des animaux et les revenus des producteurs. Mots clés: Exploitation agricole, date de semis, Cultures fourragères, M. pruriens, zone cotonnière. English Title: Production of Mucuna pruriens fodder for animal feed and its gross margin in the cotton-growing zone of Mali In Mali's cotton-growing zone, there is a large deficit in animal feed. To improve the availability of fodder resources, research in partnership with producers has introduced the cultivation of Mucuna pruriens into the farming environment. This study aims ed at evaluat’hg the performance of M. pruriens in the production of fodder for animals. The trials were conducted by 25 producers in 5 sites during the 2015-2016, 2016-2017 and 2017-2018 crop years. The trials were divided into two test plots: pure culture of M. pruriens and M. pruriens/corn combination. The average biomass production of pure M. pruriens over the 3 cropping seasons was 4363±1,491kg MS/ha. This production covers the dry matter requirement of 7.76±2.65 Btu for 90 days. For the association, the biomass production was 5449±1,766 kg DM/ha, covering the dry matter requirement of 9.69±3.14 Btu for 90 days. The gross margin of the pure culture of M. pruriens is 786 060±298 140 FCFA/ha. For the association, it is 850 917±36 1887 FCFA/ha. The cultivation of M. pruriens promotes the integration of agriculture and livestock while improving animal nutrition and the income of producers. Keywords: Farm, sowing date, fodder crops, M. pruriens, cotton are

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Sandoval Fernández, Liseth, Andrés Zúñiga Orozco, Alexander Mendoza Luna, Karla Montero Jara, and Wagner Peña Cordero. "Efecto de la incorporación de Zeolita natural y Mucuna pruriens en el cultivo de arroz (Oryza sativa L.) bajo condiciones controladas en Upala, Alajuela, Costa Rica." Repertorio Científico 23, no. 1 (June 30, 2020): 19–28. http://dx.doi.org/10.22458/rc.v23i1.2941.

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Se utilizó una fuente de abono verde, Mucuna pruriens a una dosis de 120 g/m2 y otra fuente de mineral Zeolita con dosis de 152 g/m2, en 7 tratamientos. Se logró determinar que el tratamiento de Mucuna pruriens y fertilización como el mejor en rendimiento, incluso mejor que el testigo comercial y otros tratamientos, además con una calidad de grano aceptable, también contribuyendo en una utilización eficiente del nitrógeno en la planta y una buena incorporación de materia orgánica al suelo. Otros efectos y factores involucrados bajo las condiciones de este ensayo son discutidos.

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Ojokoh, A. O., O. E. Fayemi, and O. A. Akinseye. "Enhancement of nutritional quality of rice flour with mucuna beans (Mucuna pruriens)." African Journal of Food Science 13, no. 9 (September 30, 2019): 196–202. http://dx.doi.org/10.5897/ajfs2018.1733.

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Adebowale, K. O., and O. S. Lawal. "Foaming, gelation and electrophoretic characteristics of mucuna bean (Mucuna pruriens) protein concentrates." Food Chemistry 83, no. 2 (November 2003): 237–46. http://dx.doi.org/10.1016/s0308-8146(03)00086-4.

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I, Eze G., Oriakhi K, Owolabi O. J, and Innih S. O. "Effects of Aqueous Leaf Extract of Mucuna pruriens in rats intoxicated with lead acetate." International Journal of Forensic Medical Investigation 3, no. 2 (April 25, 2018): 25. http://dx.doi.org/10.21816/ijfmi.v3i2.60.

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Mucuna pruriens (velvet beans) is an unconventional legume commonly found in the tropical regions of Africa with several ethnomedicinal uses. The present study was designed to investigate the effect of aqueous extract of Mucuna pruriens leaves in rats intoxicated with lead acetate. Thirty rats were divided into six groups (five rats per group). Group I (control group) was given distilled water only, group II was intoxicated with lead acetate (100 mg/kg) only, group III was administered M. pruriens extract (600 mg/kg) only daily for a period of 28 days, while groups IV, V and VI animals were co-administered M. pruriens extractat at different concentrations of 300, 600 and 1200 mg/kg body weight daily for 28 days. After 28 days of experiment, the animals where sacrificed. Blood samples were collected for some biochemical parameters and organs harvested for histology. The results showed that there were no significant differences in direct bilirubin, total protein, albumin and globulin, but significant increase (P˂0.05) in ALT after 28 days of intoxication with lead acetate when compared with the control. However there was no significant difference in ALP activities. Administration of aqueous extract of M. pruriens leaves at a dose of 600 mg/kg body weight for 28 days showed a significant increase (P˂0.05) in direct bilirubin, total protein, albumin, globulin, AST andALT, but significantly reduced ALP activities. Co-administration of the crude aqueous extract (300, 600 and 1200 mg/kg), did not show any ameliorating effect after 28 days when compared to rats intoxicated with lead acetate, but showed mild reduction in ALP activities with no significant changes in ALT and AST activities. Mucuna pruriens extract did not posses ameliorative effect in rats intoxicated with lead acetate, but showed potentials of resolving anaemia from the histopathological result.

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Liadi, Vivian Citra, Ni Wayan Wisaniyasa, and Ni Nyoman Puspawati. "STUDI SIFAT FUNGSIONAL DAN KIMIA TEPUNG KECAMBAH KACANG KORO BENGUK (Mucuna pruriens L.)." Jurnal Ilmu dan Teknologi Pangan (ITEPA) 8, no. 2 (June 21, 2019): 131. http://dx.doi.org/10.24843/itepa.2019.v08.i02.p03.

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The purpose of this study was to determine the functional and chemical properties of mucuna bean sprout flour. This study was conducted using 48 hour germination and without germination of mucuna bean, and each treatment was repeated three times. Mucuna bean flour and mucuna bean sprouts flour were tested for rendemen, functional properties (water absorption, oil absorption, swelling volume, and solubility), and chemical properties (moisture content, ash content, protein content, fat content, carbohydrate content, and HCN content). The results showed that germination of mucuna bean had a very significant effect on rendemen, water absorption, oil absorption, ash content, moisture content, a significant effect on fat content, carbohydrate content, and had no significant effect on swelling volume, solubility, protein content, and HCN content. The results showed that rendemen of mucuna bean sprout flour was 63.93% (db), the functional properties of mucuna bean sprout flour were water absorption 1.67 ml H2O/g solid, oil absorption 2.17 ml oil/g solid, swelling volume 8.68 ml/g, and solubility 25.76%, while the chemical properties of mucuna bean sprout flour were water content 8.10%, ash content 2.87%, protein content 36.33%, fat content 10.77%, carbohydrate content 41.92%, and HCN content 5.39 mg/kg.

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Francis, B., and C. N. Uchendu. "Extracellular Calcium and Induction of Uterine Muscle Contraction by Aqueous Ethanolic Leaf Extract of Mucuna pruriens." Journal of Applied Sciences and Environmental Management 24, no. 2 (April 16, 2020): 231–35. http://dx.doi.org/10.4314/jasem.v24i2.6.

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Calcium (Ca2+) serves as an essential signaling molecule in biological systems, regulating a wide range of cellular processes of which uterine smooth muscle contraction is among. The present study was designed to evaluate the involvement of Ca2+ on isolated uterine muscle contraction induced by aqueous ethanolic leaf extract of Mucuna pruriens (M. pruriens). Uterine muscle contraction induced by the extract was concentration-dependent and was completely abolished (100%; P<0.05) in nominally Ca2+ -free physiological salt solution and in solutions containing (EGTA 1.5 mmol), lanthanium chloride (1.5 and 3 mmol), caffeine (3and 4.4 mmol) and verapamil (0.007-0.14 μmol). It is concluded that the inability of the extract to produce contractions in Ca2+ -free media, indicates that it lacks the ability to mobilize calcium from intracellular storage sites. Hence, its uterine stimulatory property is therefore solely dependent on extracellular Ca2+. Keywords: Calcium, Mucuna pruriens, Uterus, Contraction.

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Chittasupho, Chuda, Sarin Tadtong, Suwanna Vorarat, and Narisa Kamkaen. "Physical, Chemical, and Microbiological Stability of Mucuna pruriens Effervescent Powders and Suspension." Key Engineering Materials 859 (August 2020): 145–50. http://dx.doi.org/10.4028/www.scientific.net/kem.859.145.

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Mucuna pruriens is a tropical leguminous plant containing L-dopa which is the main active ingredient for Parkinson’s disease therapy. The objective of this study was to investigate the physical, chemical, and microbiological stability of M. pruriens seed extract effervescent powders and suspension. The effervescent powders and suspension were prepared using freeze dried M. pruriens seed extract and were stored at 4 °C, 30 °C, and 45 °C. Physical stability was evaluated by observing appearance and determining rheological behavior. Chemical stability was evaluated by HPLC assay of L-dopa content in the formulation. Bacterial, fungal and mold contaminations were assessed by 3MTM PetrifilmTM count plates. Both formulations showed good physical stability. The degradations of L-dopa in effervescent powders and suspension were fitted to pseudo-zero order and second order kinetic models, respectively. M. pruriens seed extract effervescent powders was found to have the longest half-life, about 112 days, when it was stored at 4 °C. The results suggested that M. pruriens seed extract should be formulated in effervescent powders and stored at 4°C to prevent physical and chemical degradation.

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Nwankwoala, Reginald NP, and OA Georgewill. "The extract of Mucuna pruriens possesses histamine activity." Asian Pacific Journal of Tropical Medicine 3, no. 1 (January 2010): 29–31. http://dx.doi.org/10.1016/s1995-7645(10)60026-0.

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Salau, O. A, Odeleye, and M. O. "Antimicrobial activity of Mucuna pruriens on selected bacteria." African Journal of Biotechnology 6, no. 18 (September 19, 2007): 2091–92. http://dx.doi.org/10.5897/ajb2007.000-2324.

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Rai, Sachchida Nand, Hareram Birla, Walia Zahra, Saumitra Sen Singh, and Surya Pratap Singh. "Immunomodulation of Parkinson’s disease using Mucuna pruriens (Mp)." Journal of Chemical Neuroanatomy 85 (November 2017): 27–35. http://dx.doi.org/10.1016/j.jchemneu.2017.06.005.

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Jimoh, Mahboob Adekilekun, Oladayo Amed Idris, and Muhali Olaide Jimoh. "Cytotoxicity, Phytochemical, Antiparasitic Screening, and Antioxidant Activities of Mucuna pruriens (Fabaceae)." Plants 9, no. 9 (September 22, 2020): 1249. http://dx.doi.org/10.3390/plants9091249.

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This study aimed at assessing the biological activities of Mucuna pruriens seeds using cytotoxicity, phytochemical, antiparasitic screening, and antioxidant assays. Mature fruits of M. pruriens were harvested from Fort Hare University’s Research Farm located in Alice, South Africa. The collected seeds were pulverized in a standard process and taken to the laboratory for crude extraction and further treatments. Cytotoxic, antimalarial, and trypanocidal effects of crude extracts obtained from ethanol and water were tested, while the total phenolic, proanthocyanidin, and flavonoid contents of the aqueous extracts as well as their pharmacological activities were determined in vitro using 2,2-diphenyl-1-picrylhydrazyl ethanol (DPPH), ferric reducing antioxidant power (FRAP), and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays. Although the extracts showed mild antiparasitic (antiplasmodial and trypanocidal) effects, results from the cytotoxic experiment revealed that M. pruriens is not toxic to human cervix adenocarcinoma (HeLa) cells when tested using 50 µg/mL of extracts. It was observed that the seeds were remarkably rich in phenol (3730.1 ± 15.52 mg gallic acid equivalent (GAE)/g) compared to flavonoids (63.03 ± 1.95 mg quercetin equivalent (QE)/g) and proanthocyanidin (18.92 ± 1.09 mg catechin equivalent (CE)/g). Also, the antioxidant activities of the extracts were comparable to those of the standard antioxidant drugs (rutin and gallic acid) used, in a concentration-dependent manner. There was a direct relationship between phenolic acid content and antioxidant effects. It is therefore suggested that M. pruriens seeds be incorporated into human diets as a supplement to promote healthy living. Pharmaceutical industries with a particular interest in natural phenolic acids should consider using seeds of M. pruriens as pharmaceutical precursors.

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Pamo Tendonkeng, E., D. Ko Awono, F. Tendonkeng, Anne Clarisse Ngo Tama, and B. Boukila. "Performances de croissance des caprins supplémentés avec du Mucuna pruriens au Nord Cameroun." Revue d’élevage et de médecine vétérinaire des pays tropicaux 63, no. 1-2 (January 1, 2010): 47. http://dx.doi.org/10.19182/remvt.10109.

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L’influence du niveau de supplémentation avec Mucuna pruriens sur les performances de croissance des boucs et la digestibilité des rations pendant la saison sèche au Nord Cameroun a été étudiée à la station polyvalente de l’Institut de recherche agricole pour le développement de Garoua entre novembre 2004 et juillet 2005. Au total, 24 boucs Nains de Guinée ont été divisés en trois groupes de huit boucs chacun, nourris à base d’Andropogon gayanus, de Ficus sycomorus, et supplémentés avec 0, 100 et 150 g de Mucuna pruriens. L’évaluation du poids vif, du gain moyen quotidien et de la note d’état corporel a été effectuée tous les 14 jours pendant 90 jours. Au terme de cette phase, l’évaluation du poids carcasse et le rendement carcasse ont été effectués sur deux boucs abattus par lot. Ensuite, neuf boucs ont été répartis en trois groupes de trois animaux chacun et chaque groupe a été soumis à l’un des trois traitements précédents, afin d’étudier l’influence du niveau de supplémentation de M. pruriens sur la digestibilité de la ration de base. Les résultats ont indiqué qu’en l’absence de M. pruriens dans la ration, le poids vif, le gain moyen quotidien et la note d’état corporel ont été respectivement de 10,44 kg, - 10 g et 1,87. En présence de 100 g de M. pruriens dans la ration, le poids vif, le gain moyen quotidien et la note d’état corporel ont été respectivement de 12,16 kg, 9 g et 2,94, contre 12,98 kg, 18 g et 3,56 avec une ration contenant 150 g de M. pruriens. Le poids carcasse, le rendement carcasse et le poids avant abattage ont augmenté significativement (P < 0,05) avec l’accroissement du niveau de M. pruriens dans la ration. La digestibilité apparente de la matière organique a été de 45,25, 62,34 et 70,97 p. 100 respectivement avec les rations contenant 0, 100 et 150 g de M. pruriens. La digestibilité de l’azote a été de 38,46, 55,29 et 60,95 p. 100 respectivement avec les mêmes rations. Il apparaît ainsi que la supplémentation des rations avec M. pruriens pendant la saison sèche permet d’améliorer la digestibilité de la ration et les performances de croissance des boucs.

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Kusuma*, Srilakshmi, Aniel Kumar O., Lakshmi Narayana K., Sudhakar Pola, and Venkata Reddy K. "In vitro Physicochemical, Phytochemical, Antimicrobial and Antidiabetic studies on Mucuna pruriens (Linn.) DC seeds." International Journal of Bioassays 5, no. 06 (May 31, 2016): 4650. http://dx.doi.org/10.21746/ijbio.2016.06.0012.

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Diabetes is one of the most common endocrine diseases characterized by hyperglycemia due to absolute or relative deficiency of insulin which is currently affecting the citizens of both developed and developing countries. According to Williams textbook of endocrinology in 2013 it was estimated that over 382 million people throughout the world had diabetes. Plants have long been used for the treatment of diabetes, particularly in developing countries where most people have limited resources and do not have access to modern treatment. The presented study is aimed to evaluate the Mucuna pruriens seed extracts for its in vitro physiochemical, phytochemical, antioxidant and anti-diabetic studies. From the studies different solvent extracts of hexane and chloroform showed little or no activity on all assays performed whereas methanol extract of Mucuna pruriens showed significant bio properties. The preliminary studies of this plant crude methanol extract exhibited maximum compounds, hence the methanol extracts have under taken for its alpha amylase and alpha glucosidase inhibition activity. On the basis of the results obtained in the present investigation, it can be concluded that methanol extract of Mucuna pruriens had significant bioactive properties and may provide a support to use of the plant in traditional medicine for the management of diabetes.

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Concessao, Preethi, Laxminarayana Kurady Bairy, and Archana Parampalli Raghavendra. "Protective effect of Mucuna pruriens against arsenic-induced liver and kidney dysfunction and neurobehavioral alterations in rats." August-2020 13, no. 8 (2020): 1555–66. http://dx.doi.org/10.14202/vetworld.2020.1555-1566.

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Background and Aim: Intoxication of arsenic in rats is known to result in neurological effects as well as liver and kidney dysfunction. Mucuna pruriens has been identified for its medicinal properties. The aim of the study was to investigate the protective effect of aqueous seed extract of M. pruriens on sodium arsenite-induced memory impairment, liver, and kidney functions in rats. Materials and Methods: The experiment was divided into short-term treatment (45 days) and long-term treatment (90 days), with each group divided into nine sub-groups consisting of six animals each. Sub-groups 1 and 2 served as normal, and N-acetylcysteine (NAC) controls, respectively. Sub-groups 3-9 received sodium arsenite in drinking water (50 mg/L). In addition, sub-group 4 received NAC (210 mg/kg b.wt) orally once daily, sub-groups 5-7 received aqueous seed extract of M. pruriens (350 mg/kg b.wt, 530 mg/kg b.wt, and 700 mg/kg b.wt) orally once daily and sub-groups 8 and 9 received a combination of NAC and aqueous seed extract of M. pruriens (350 mg/kg b.wt and 530 mg/kg b.wt) orally once daily. Following the treatment, the blood was drawn retro-orbitally to assess the liver (serum alanine transaminase [ALT], serum aspartate transaminase, and serum alkaline phosphatase) and kidney (serum urea and serum creatinine) functions. Learning and memory were assessed by passive avoidance test. Animals were sacrificed by an overdose of ketamine, and their Nissl stained hippocampal sections were analyzed for alterations in neural cell numbers in CA1 and CA3 regions. Results: In the short-term treatment, groups administered with M. pruriens 530 mg/kg b.wt alone and combination of NAC + M. pruriens 350 mg/kg b.wt exhibited a significant improvement in memory retention, less severe neurodegeneration, and decrease in serum ALT levels. In long-term treatment, groups administered with M. pruriens 700 mg/kg b.wt alone and combination of NAC+M. pruriens 350 mg/kg b.wt, respectively, showed better memory retention, decreased neural deficits, and reduced levels of kidney and liver enzymes. Conclusion: The seed extract of M. pruriens showed significant enhancement in memory and learning. The number of surviving neurons in the CA1 and CA3 regions also increased on treatment with M. pruriens. Serum ALT, serum urea, and serum creatinine levels showed significant improvement on long-term treatment with M. pruriens.

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Ameh, Matthew P., Mamman Mohammed, Yusuf P. Ofemile, Magaji G. Mohammed, Ada Gabriel, and Akefe O. Isaac. "Detoxifying Action of Aqueous Extracts of Mucuna pruriens Seed and Mimosa pudica Root Against Venoms of Naja nigricollis and Bitis arietans." Recent Patents on Biotechnology 14, no. 2 (May 11, 2020): 134–44. http://dx.doi.org/10.2174/1872208313666191025110019.

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Background: The World Health Organization included snakebite envenomation among Neglected Tropical Diseases in 2017. The importance of natural products from plants is enormous, given that most prescribed drugs originate from plants. Among this is Mucuna pruriens and Mimosa pudica, with many registered patents asserting their health benefits. Objective: This study investigated the in vitro neutralizing effects of Mucuna pruriens seed and Mimosa pudica root extracts on venoms of Naja nigricollis and Bitis arietans. Methods: In mice, the LD50 and phytochemical analysis of M. pruriens and M. pudica plant extracts were carried out prior to the evaluation of their haemolytic and fibrinolytic effect. Their effects on the activities of phospholipase A2 (PLA2) were also assessed. Results: At a concentration of 50 mg/ml, both plant extracts were found to neutralize the fibrinolytic activity of N. nigricollis, but 400 mg/ml was required to neutralize the fibrinolytic activity of B. arietans. In haemolytic studies, 50 mg/ml concentration of M. pruriens extract suppressed haemolysis caused by N. nigricollis venom by 70% but at the same concentration, M. pudica extract reduced haemolysis by 49.4%. M. pruriens, at 50 mg/ml concentration, only inhibited phospholipase A2 activity by 7.7% but higher concentrations up to 400mg/ml had no effect against the venom of N. nigricollis; at 200 mg/ml. M. pudica extract inhibited PLA2 activity by 23%. Conclusion: The results suggest that M. pruriens and M. pudica may be considered as promising antivenom agents for people living in a snake-bite prone environment.

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ESONU, B. O. "COMPARATIVE EVALUATION OF RAW AND UREA/TOASTED VELVET BEAN (Mucuna pruriens) FOR BROILER CHICKS." Nigerian Journal of Animal Production 28, no. 1 (January 7, 2021): 40–44. http://dx.doi.org/10.51791/njap.v28i1.1855.

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Feeding trials lasting 28 days were conducted to investigate the nutritive value of raw and urea treated/toasted mucuna bean for broiler chicks. Raw mucuna bean contains 30.33& crude protein, 7.20% crude fibre, 6.9% ether extract and 5.0% ash. Mucuna bean seeds were divided into two batches. One batch was ground raw and the other batch was ground raw, treated with 3% of its weight of urea and toasted. Mucuna bean meals so produced were then used to formulate broiler chick diets incorporfating these meals at 5% and 10% respectively. One hundred and fifty (150), 7-day-old Anak broiler chicks were randomly assigned to the five dietary treatments in a completely randomized design (CRD) and each treatment group was further sub-divided into three replicates. Feed intake of the birds was inconsistent with the treatments, increasing at 5% inclusion level and decreasing at 10% inclusion level (P<0.05). Body weight gain of the birds followed the same pattern as feed intake, decreasing at a higher dietary level of mucuna bean meal at all levels reduced cost of feed and meat production. The results of this trial suggest that broiler chicks could not tolerate raw mucuna bean meal beyond 5% dietary level. Urea treatment at this level (3% of the weight of mucuna bean) and toasting did not improve the nutritive value of mucuna been beyond 5% dietary level.

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Ferdous, Shifat E., Mamunur Rahman, Firoj Ahmed, and Md Abdul Muhit. "Phytochemical Analysis, Antioxidant and Cytotoxic Activities of Mucuna pruriens Leaves." Dhaka University Journal of Pharmaceutical Sciences 20, no. 1 (June 14, 2021): 103–9. http://dx.doi.org/10.3329/dujps.v20i1.54038.

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Mucuna pruriens is a tropical legume native to Africa, India and Bangladesh and is widely cultivated in tropical countries. In this study, a crude methanolic extract of the leaves of M. pruriens was investigated for its chemical constituents and to explore the phenolic and flavonoid content, antioxidant, cytotoxic and antimicrobial activities using established protocols. From the ethyl acetate soluble fraction of the crude methanol extract, three known compounds namely ferulic acid (1), 2-(5-methoxy-1-benzofuran-3-yl)-N-ethylethanamine (2) and stizolamine (3) were isolated and their structures were elucidated by the analysis of NMR spectral data. The crude extract was found to possess phenolic content of 216.16 μg/g whereas the concentration of flavonoid was found to 214.8 μg/g expressed in quercetin standard. Free radicals generated through DPPH were neutralized by crude methanolic extract and the IC50 value was obtained as 19.63 μg/ml. Regression analysis during brine shrimp lethality test enumerated LC50 value of crude methanolic extract at 10.72 μg/ml and was significant compared to the positive standard. The crude methanolic extract of leaf of M. pruriens did not show any significant antimicrobial activity against the organisms used in our test. Dhaka Univ. J. Pharm. Sci. 20(1): 103-109, 2021 (June)

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Longhi, Joy Ganem, Elisa Perez, Jair José de Lima, and Lys Mary Bileski Cândido. "In vitro evaluation of Mucuna pruriens (L.) DC. antioxidant activity." Brazilian Journal of Pharmaceutical Sciences 47, no. 3 (September 2011): 535–44. http://dx.doi.org/10.1590/s1984-82502011000300011.

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Mucuna pruriens (L). Dc is a plant of the Fabaceae family, commonly known as velvet bean, itchy bean, chiporro bean, mucuna, among others. This plant has several medicinal properties, including its potential to treat Parkinson's disease (PD). International studies have shown that this plant surpasses the benefits of the substance levodopa in the treatment of PD. Taking into account that nerve cells are highly sensitive to oxidative substances, this study evaluated the antioxidant activity of mucuna and compared it to that of levodopa. The plant seeds' phenolic concentration was quantified by using the Folin-Denis reagent and the antioxidant activity assays were performed by using three different methods: the reduction of the phosphomolybdenium complex, the reduction of radical 1,1-diphenyl-2-picrylhydrazyl (DPPH•) and the formation of radical monocation ABTS•+, from the acid [2-2'-azinobis (3-ethylbenzothiazoline-6-sulfonate)]. Results showed that M. pruriens presents high antioxidant capacity, although not superior to isolated levodopa antioxidant capacity. Therefore, further studies should be performed to elucidate the activity of this plant in humans.

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Paudyal, Som Prasad, and Vimal NP Gupta. "Bio-chemical characterization of rhizobia isolated from root nodules of Velvet bean (Mucuna pruriens L.)." Our Nature 15, no. 1-2 (December 25, 2017): 7–12. http://dx.doi.org/10.3126/on.v15i1-2.18788.

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Rhizobia are the symbiotic bacteria found in the soil which have potential ability to convert atmospheric di-nitrogen into usable form. A total of ten rhizobial strains were isolated from the root nodules of a medicinal legume Mucuna pruriens (L.) that commonly grow in the foothills of the Himalaya. All the ten strains isolated from different locations of same area were morphologically, biochemically and physiologically characterized based on the Bergey’s Manual of systematic Bacteriology. They were tested for the antibiotics sensitivity. The isolates showed high sensitivity to amoxicillin and least to erythromycin. Authentication test was done in eleven legumes but shown nodulations only in Trigonella foenum-graecum, Mucuna pruriens and Medicago sativa. The morphology, physiology, biochemical and infection test studies carried out justifies that the bacteria isolated belonged to the species of Rhizobium meliloti.

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Ladino Manjarrés, Diego Alexander, and Harold Bastidas López. "Componentes naturales para el control de antracnosis (Colletotrichum gloeosporoides) en guanabana (Annona muricata L.)." Revista Sistemas de Producción Agroecológicos 8, no. 1 (June 30, 2017): 12–26. http://dx.doi.org/10.22579/22484817.693.

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El cultivo de guanábana (Annona muricata L.) es uno de los más populares en Colombia, puesto que su fruto es muy consumido y requiere de buenos cuidados para su comercialización, en los últimos años se ha ido incrementando el área sembrada. La aplicación de productos químicos a estos árboles para la disminución de la enfermedad que los afecta, antracnosis (Colletotrichum gloeosporoides) es una constante; por lo tanto este proyecto investigó sobre otras alternativas probando productos orgánicos elaborados a base de extractos vegetales o biofertilizantes que puedan disminuir y controlar la incidencia y severidad de esta enfermedad, con el fin de reemplazar los agroquímicos que dejan residualidad y pueden ser perjudiciales para la salud humana. Para estas pruebas se establecieron los siguientes tratamientos: Mucuna pruriens (mucuna) (T1), Datura stramonium (borrachero) (T2) y un biofertilizante (T3) para comparar la severidad de la enfermedad contra un testigo (T0); se aplicó un diseño completamente al azar, cuatro tratamientos, tres replicaciones con tres unidades experimentales, se realizaron evaluaciones a los siete, doce y dieciocho días después de la aplicación de estos productos. El porcentaje de disminución con respecto a la severidad inicial que se tomó como cero (0), arroja que los productos que dieron un resultado positivo (P<0.05) en las aplicaciones de manera progresiva contra la enfermedad antracnosis fueron: el extracto con la planta Mucuna pruriens y el biofertilizante siendo de 78.35 Vs 18.36 y 50.81 Vs 20%, respectivamente comparando la severidad inicial con la presentada a los 18 días después de la aplicación de productos. Se concluye que los mejores tratamientos fueron el de Mucuna pruriens seguido del biofertilizante.

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Journal articles on the topic 'Mucuna pruriens'

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