Relevant bibliographies by topics / Multi-component one-pot reaction

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Academic literature on the topic 'Multi-component one-pot reaction'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Multi-component one-pot reaction"

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Dömling, Alexander. "Isocyanide Based Multi Component Reactions in Combinatorial Chemistry." Combinatorial Chemistry & High Throughput Screening 1, no. 1 (1998): 1–22. http://dx.doi.org/10.2174/138620730101220118143111.

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: Although usually regarded as a recent development, the combinatorial approach to the synthesis of libraries of new drug candidates was first described as early as 1961 using the isocyanide-based one-pot multicomponent Ugi reaction. Isocyanide-based multi component reactions (MCR's) markedly differ from their usual two component counterparts. In the context of combinatorial chemistry, they offer more structural variations, more accessible compounds and more diversity than any other previously known reaction. This review examines the history of isocyanide based MCR's and their applicability in
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Wang, Qi-Fang, and Chao-Guo Yan. "Efficient synthesis of diarylidene octahydroacridines by one-pot multi-component tandem reactions." Open Chemistry 6, no. 3 (2008): 404–9. http://dx.doi.org/10.2478/s11532-008-0027-2.

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AbstractA one-pot multi-component reaction is developed for the efficient synthesis of 4,5-dibenzylidene octahydroacridines in high yields. The reaction is performed by the tandem reaction of three molar equivalent aromatic aldehydes with two molar equivalent 4-alkylcyclohexanone in the system of NH4OAc/HOAc under microwave irradiation.
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Borpatra, Paran J., Bhaskar Deka, Basanta K. Rajbongshi, Mohit L. Deb, and Pranjal K. Baruah. "One-pot sequential multi-component reaction: Synthesis of 3-substituted indoles." Synthetic Communications 48, no. 16 (2018): 2074–82. http://dx.doi.org/10.1080/00397911.2018.1482352.

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Li, Jun, Constantin G. Daniliuc, Gerald Kehr, and Gerhard Erker. "An olefin-based multi-component reaction to yield 1,2-azaborolidine derivatives." Dalton Transactions 51, no. 5 (2022): 1775–78. http://dx.doi.org/10.1039/d1dt04337d.

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Basirat, Narjes, Seyed Sajad Sajadikhah, and Abdolkarim Zare. "Multi-component synthesis of piperidines and dihydropyrrol-2-one derivatives catalyzed by a dual-functional ionic liquid." Journal of Chemical Research 44, no. 1-2 (2019): 20–24. http://dx.doi.org/10.1177/1747519819883881.

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N,N,N’, N’-tetramethyl- N,N’-bis(sulfo)ethane-1,2-diaminium mesylate ([TMBSED][OMs]2) was employed for the synthesis of piperidines and dihydropyrrol-2-ones via one-pot multi-component reactions in simple and green processes. This pseudo five-component reaction of aromatic aldehydes, anilines and alkyl acetoacetates was carried out under reflux conditions in ethanol to afford substituted piperidines. Also, dihydropyrrol-2-one derivatives were synthesized by means of four-component reactions of various amines, dialkyl acetylenedicarboxylates and formaldehyde in ethanol at room temperature. The
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Goyal, Sandeep, Jatinkumar K. Patel, Mukesh Gangar, Kapil Kumar, and Vipin A. Nair. "Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly." RSC Advances 5, no. 5 (2015): 3187–95. http://dx.doi.org/10.1039/c4ra09873k.

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Chang, Wong-Jin, Manohar V. Kulkarni, and Chung-Ming Sun. "Regioselective one-pot three component synthesis of chiral 2-iminoselenazolines under sonication." RSC Advances 5, no. 118 (2015): 97113–20. http://dx.doi.org/10.1039/c5ra18763j.

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Yan, Chao-Guo, Qi-Fang Wang, Xi-Mei Cai, and Jing Sun. "One-pot multicomponent synthesis of substituted 5,7-dihydro-1,6-naphthyridines and 5,6,7,8-tetrahydroquinolines." Open Chemistry 6, no. 2 (2008): 188–98. http://dx.doi.org/10.2478/s11532-008-0003-x.

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AbstractAn one-pot approach was developed for the synthesis of substituted 5,7-dihydro-1,6-naphthyridines and 5,6,7,8-tetrahydroquinolines with moderate to good yields. This pathway is a modified two-step synthesis of Kröhnke pyridine and involves a four-component tandem reaction of N-phenacylpyridinium bromide, aromatic aldehydes, substituted or nitrogen-containing cyclic ketones and a nitrogen source. This multi-component reaction is performed using microwave irradiation heating of the reaction substrates under an environment of NH4OAc/HOAc.
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Guo, Jiaomei, Hongjie Miao, Yang Zhao, et al. "An unexpected multi-component one-pot cascade reaction to access furanobenzodihydropyran-fused polycyclic heterocycles." Chemical Communications 55, no. 36 (2019): 5207–10. http://dx.doi.org/10.1039/c9cc02170a.

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An unexpected multi-component one-pot cascade reaction of hydroxyketones with ortho-hydroxychalcones has been developed to afford an array of new furanobenzopyran-fused polycyclic compounds with complex molecular architectures.
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Patel, Dhaval B., Jagruti A. Parmar, Siddharth S. Patel, Unnati J. Naik, and Hitesh D. Patel. "Recent Advances in Ester Synthesis by Multi-Component Reactions (MCRs): A Review." Current Organic Chemistry 25, no. 5 (2021): 539–53. http://dx.doi.org/10.2174/1385272825666210111111805.

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The synthesis of ester-containing heterocyclic compounds via multicomponent reaction is one of the preferable processes in synthetic organic chemistry and medicinal chemistry. Compounds containing ester linkage have a wide range of biological applications in the pharmaceutical field. Therefore, many methods have been developed for the synthesis of these types of derivatives. However, some of them are carried out in the presence of toxic solvents and catalysts, with lower yields, longer reaction times, low selectivities, and byproducts. Thus, the development of new synthetic methods for ester s
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Dissertations / Theses on the topic "Multi-component one-pot reaction"

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Pelletier, Sophie Marie-Clémentine. "One-pot nitro-Mannich cascade reactions : new methodologies and synthetic applications." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:283641bf-bb4e-48a8-8a28-2e048b8c4ea6.

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Pyrrolidine and pyrrolidinone rings are common motifs found in many biologically active natural products and drugs. Accordingly, our work focuses on the development of new methodologies for their one-pot synthesis. An efficient diastereoselective nitro-Mannich / lactamisation reaction cascade of methyl 3-nitropropanoate with cyclic and acyclic imines for the direct preparation of trans-monocyclic and fused tricyclic pyrrolidinone derivatives was developed. The reaction is easy to perform, broad in scope and tolerates a wide variety of functional groups. For the monocyclic methodology, 28 examp
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Book chapters on the topic "Multi-component one-pot reaction"

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Ohta, Yusuke. "Facile Synthesis of 1,2,3,4-Tetrahydro-β-Carbolines by One-Pot Domino Three-Component Indole Formation and Nucleophilic Cyclization." In Copper-Catalyzed Multi-Component Reactions. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-15473-7_3.

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Espeel, Pieter, and Filip E. Du Prez. "One-Pot Double Modification of Polymers Based on Thiolactone Chemistry." In Multi-Component and Sequential Reactions in Polymer Synthesis. Springer International Publishing, 2014. http://dx.doi.org/10.1007/12_2014_304.

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Ugi, Ivar, and Alexander Dömlingꝉ. "Multi-component reactions (MCRs) of isocyanides and their chemical libraries." In Combinatorial Chemistry. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199637546.003.0009.

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Abstract In principle, all chemical reactions correspond to equilibria between one or two reactants and products. In practice, however, preparative chemical reactions proceed irreversibly and, in the absence of competing reactions, extremely high yields of pure products can be obtained (1-3). If more than two (n > 2) reactants are required for the synthesis of a product, usually several (at least n - 1) preparative steps must be carried out. The more preparative steps there are, the more isolation and characterization work must be achieved, and the lower the yields are after each step o
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