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Journal articles on the topic 'Multi-drug resistance isolates'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Flayyih, May Talib, and Ayat Ahmed Najm. "Expression of Pili Genes (ebpA and ebpC) Associated with Multi Drug Resistant Enterococcus faecalis Isolates." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 33, no. 3 (2024): 72–79. http://dx.doi.org/10.31351/vol33iss3pp72-79.

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The antibiotic susceptibility was determined for 118 clinical E. faecalis isolates , the isolates showed various levels of susceptibilities to different antibiotics and 70.5% of these isolates were multidrug resistant. The relative expression of ebpA gene in six multidrug resistance E. faecalis isolates was determined in comparison with antibiotic-sensitive isolates selected as a control sample. The isolate 21 from root canal (multi drug resistance) showed increasing in expression in comparison with antibiotic sensitive isolates of E. faecalis. The relative expression of ebpC gene in multidrug

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2

Onemu, S. O., Faith Ademulegun, M. O. Onemu-Metitiri, Emmanuel Ifeanyi Obeagu, and Abdulwasiu Oladele Hassan. "The Contribution of Curable Plasmid-Mediated Resistance in Isolates of Staphylococcus aureus at the University of Benin Teaching Hospital, Benin City, Nigeria." Asian Journal of Dental and Health Sciences 3, no. 3 (2023): 30–32. http://dx.doi.org/10.22270/ajdhs.v3i3.50.

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aureus, is an important human pathogen and commensal that is responsible for infections ranging from minor to deep-seated life-threatening conditions. Multi-drug resistant S. aureus or MRSA is a major cause of hospital acquired infection (HAIs) or nosocomial infections with consequential reduction in treatment options and overtly increased cost of healthcare, morbidity and mortality. The study was conceived to determine the contribution of curable transmissible plasmids to the ever-increasing proportion of multi-drug resistant S. aureus at the University of Benin Teaching Hospital, Benin City.

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Jain, Ruchi, Nita Pal та Saroj Hooja. "Prevalence of β-lactamase production and multi-drug resistance among uropathogenic Escherichia coli isolates at a tertiary care hospital of North-western India". Asian Journal of Medical Sciences 12, № 7 (2021): 27–32. http://dx.doi.org/10.3126/ajms.v12i7.35046.

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Background: E.coli is the most common organism causing UTI. Inappropriate and widespread use of broad-spectrum antibiotics has resulted in development of multi-drug resistance and β-lactamases producing strains. Aims and Objective: To assess β-lactamase production and multi-drug resistance among uropathogenic E.coli isolates. Materials and Methods: A total of 145 E.coli urinary isolates were included in this study. The isolated organisms were identified by conventional microbiological procedures. Antimicrobial susceptibility was performed by Kirby Bauer disk diffusion method. Isola

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Shah, Manali Hitenbhai, and Geeta Mukesh Vaghela. "Clinical Impact and Emerging Multi Drug Resistance of Acinetobacter Baumannii and Pseudomonas Aeruginosa Isolates." Annals of Pathology and Laboratory Medicine 5, no. 5 (2018): A389–392. http://dx.doi.org/10.21276/apalm.1774.

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5

Bitew, Adane. "High Prevalence of Multi-Drug Resistance and Extended Spectrum Beta Lactamase Production in Non-Fermenting Gram-Negative Bacilli in Ethiopia." Infectious Diseases: Research and Treatment 12 (January 2019): 117863371988495. http://dx.doi.org/10.1177/1178633719884951.

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Background: Emergence of resistance to multiple antimicrobial agents in Non-Fermenting Gram-Negative Bacilli is a major problem to public health, as it limits drug treatment options against infections. The aim of this study was to determine the prevalence of multi-drug resistance and extended spectrum beta lactamase production in Non-Fermenting Gram-Negative Bacilli. Materials and methods: Different clinical samples were collected and processed following standard procedures. Each sample was then inoculated onto culture media. Identification, drug susceptibility testing, and extended spectrum b

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6

Jibril, Abubakar, Mairo Usman Kadaura, Suleiman Farida Gachi, et al. "Multi Drug Resistance, Extensive Drug Resistance, and Pan Drug Resistance Enterobacterales from Clinical Samples in Usmanu Danfodiyo University Teaching Hospital Sokoto." EAS Journal of Parasitology and Infectious Diseases 7, no. 01 (2025): 1–6. https://doi.org/10.36349/easjpid.2025.v07i01.001.

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Antimicrobial resistance (AMR) is now recognized as one of the most serious global threats to human health in the 21st century. This study is set out to investigate the resistance pattern of Enterobacterales from clinical isolates in Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. Three hundred and twenty isolates of Enterobacterales were isolated from different clinical samples and identified using the Analytical Profile Index 20E. Antimicrobial susceptibility testing was performed using the modified Kirby-Bauer disk diffusion method, and the antibiotics tested include Augment

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7

Shelke, Rahul Rajendra, and Meera Chavan. "Screening plants for medicines against & species infections." Indian Journal of Microbiology Research 8, no. 2 (2021): 157–62. http://dx.doi.org/10.18231/j.ijmr.2021.032.

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species are multi drug resistant bacteria. These bacteria are resistant to number of antimicrobial agents. The research work was aimed at killing and inhibiting the growth of these multi drug resistant pathogens, by using phytochemicals. The phytochemicals are secondary metabolites produced by plants. According to WHO medicinal plants are best products for maintaining human health. Plants like (Behada)and (Chndan) found to be the most effective against all isolated multi drug resistant species and species. 20 pathogens were isolated on MacConkeys agar plate. Out of these isolates, all isolates

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SERGELIDIS (Δ. ΣΕΡΓKΕΛΙΔΗΣ), D., A. ABRAHIM (Α. ΑΜΠΡΑΧΙΜ), T. PAPADOPOULOS (Θ. ΠΑΠΑΔΟΠΟΥΛΟΣ), et al. "Antimicrobial susceptibility of Enterococcus spp. isolated from freshwater fish and personnel and equipment of fish markets in northern Greece." Journal of the Hellenic Veterinary Medical Society 64, no. 4 (2017): 239. http://dx.doi.org/10.12681/jhvms.15503.

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In total, 270 samples from freshwater fish and personnel and equipment from retail fish markets in three cities in northern Greece, were examined for presence of antimicrobial resistance and biogenic amine production of Enterococcus spp. strains. Enterococci were isolated from 9.6% of the samples; from 7.4% and 2.2%, respectively, Enterococcus faecium and Enterococcus casseliflavus were recovered. Isolates were tested for antibacterial susceptibility to 20 antibiotics used regularly in Greek hospitals. All isolates except one were multi drug resistant, to 7-15 antibiotics. Increased rates of r

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9

Akinnibosun, FI, and JA Adetitun. "Drug resistance and plasmid profile of bacterial isolates from automated teller machine keypads in Benin city." Bangladesh Journal of Scientific and Industrial Research 54, no. 3 (2019): 231–40. http://dx.doi.org/10.3329/bjsir.v54i3.42675.

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The purpose of this study was to investigate the drug resistance and plasmid profile of bacterial isolates from automated teller machine (ATM) keypads in Benin City, Nigeria. Samples were collected from the keypads of ATMs situated in banking premises and open access areas using stratified random sampling method at 5 different locations. Isolated bacteria were characterized by extensive phenotypic and biochemical identification procedures. Antibiotic susceptibility pattern and plasmid profile of the isolates were carried out using standard methods. The bacteria isolated were: Klebsiella sp., P

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Suhaimi, Mohd, Kam Yern, Mohd Kamaroddin, et al. "Multi-Drug Resistance Bacteria: A Case Study in Western Peninsular Malaysia Freshwaters." Journal of Tropical Life Science 11, no. 3 (2021): 285–97. http://dx.doi.org/10.11594/jtls.11.03.05.

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The emergence of antibiotic resistant bacteria in aquatic environment has led to an increase in waterborne health risks to an alarming extent. This study attempts to investigate the population of certain antibiotic resistant strains in Peninsular Malaysia.Â From the samples of 14 rivers from 7 different states in Peninsular Malaysia, a total of 203 isolates were successfully isolated. These are from rivers in Negeri Sembilan, Melaka, Selangor, Kuala Lumpur, Kedah, Kelantan and Terengganu with 35, 15, 37, 39, 24, 26 and 27 isolates, respectively. The isolates were tested for their susceptibilit

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Shrestha, Basudha, Rajesh Lal Gurubacharya, Basanta Maharjan, and Sanjit Shrestha. "Multi Drug Resistant Pathogens Causing Urinary Tract Infections in Children at Kathmandu Model Hospital." Journal of Nepal Paediatric Society 32, no. 3 (2013): 233–38. http://dx.doi.org/10.3126/jnps.v32i3.6771.

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Introduction: Antibiotic resistance of urinary tract pathogens has increased globally. Updated knowledge of the antibiotic resistance patterns of uropathogens in the health institutes is important for the selection of an appropriate empirical antimicrobial therapy. The aim of this study was to evaluate the multi drug resistant urinary isolates in the children from 1 to15 years and evaluate the options for empiric antibiotic therapy. Materials and Methods: The study was conducted from December 2011 to May 2012 in the Bacteriology laboratory, Kathmandu Model Hospital. Urine samples received in t

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Yadav, K., S. Prakash, NP Yadav, and RS Sah. "Multi-Drug Resistance of Bacterial Isolates among Dental Caries Patients." Janaki Medical College Journal of Medical Science 3, no. 1 (2016): 37–44. http://dx.doi.org/10.3126/jmcjms.v3i1.15374.

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Background and Objectives: Dental caries is a well known major oral health problem in most developing countries which has multifactorial etiology caused by many facultatively anaerobes. S. mutans is the main pathogen associated with this disease. Recently Multi-Drug Resistant (MDR) species of S. mutans were identified from the dental caries patients against many commercial antibiotics. MDR is a natural phenomenon, posing a serious worldwide threat to public health. Several therapeutic agents are available to treat or prevent tooth decay, but still global burden of the disease with MDR are emer

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Saeed, Muhammad Azeem, Abdul Haque, Aamir Ali, et al. "Relationship of drug resistance to phylogenetic groups of E. coli isolates from wound infections." Journal of Infection in Developing Countries 3, no. 09 (2009): 667–70. http://dx.doi.org/10.3855/jidc.66.

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Background: Drug resistance is a major problem in Escherichia coli isolated from surgical wound infections. In this study, we evaluated relationship between phylogenicity and drug resistance. Methodology: A total of 29 multi-drug resistant (MDR) E. coli isolates of known drug resistance genes and integron profile were selected for the present study. Triplex PCR was conducted for phylogenetic classification of these isolates into four established phylogenetic groups: A, B1, B2 and D. Statistical analysis was done to determine the association of different drug resistance genes and integrons with

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14

Geda, Daniel D., and Marigold O. Uba. "Screening of Enterobacteriaceae with antimicrobial resistance from cold, home-made beverages sold in selected food stalls of Dasmariñas City, Cavite." SDCA Journal of Biological Research 2 (June 30, 2021): 14–24. https://doi.org/10.5281/zenodo.8213338.

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Cold street beverages are popular choice of drinks in the Philippines due to its convenience and low cost. However, bacteria present in the beverages can cause public health issues. Antibiotic resistance is a growing global concern which makes infections more dangerous and harder to cure. This paper intended to isolate and identify the Enterobacteriaceae found in the cold street beverages sold on Dasmariñas Bagong Bayan, Dasmariñas, Cavite as well as determine if the isolated organisms are resistant to different kinds of antibiotics. A total of 15 isolates were collected in six (

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15

Jasim, Hayder, and Ahmad Abdul-Ameer. "PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII." Iraqi Journal of Medical Sciences 16, no. 4 (2018): 357–71. http://dx.doi.org/10.22578/ijms.16.4.2.

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Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A. baumannii), a significant nosocomial pathogen, has evolved resistance to almost all conventional antimicrobial drugs in poor hygiene and conflicts areas like Iraq. Objective:Isolate and apply bacteriophages as alternative therapeutic agents against extensively drug-resistant (XDR) and pan-drug-resistant A. baumannii and evaluation extracted native endolysin activity. Methods:Twenty-three bacterial samples were collected in Al-Imamein Al-kadhimein Med

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16

Subramanian, Nivetha, Mangaiyarkarasi Thiyagarajan, Udhayasankar Ranganathan, Sunil S. Shivekar, and R. Gopal. "Colistin Susceptibility and Plasmid Mediated mcr-1 Gene Prevalance among Multi Drug Resistant Clinical Isolates of Escherichia coli, Kebsiella pneumoniae and Pseudomonas aeruginosa - A Hospital Based Cross Sectional Study." Journal of Medical Sciences and Health 10, no. 3 (2025): 294–300. https://doi.org/10.46347/jmsh.v10.i3.24.248.

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Introduction: The treatment options for multi drug resistant (MDR) and extensively drug resistant (XDR) Gram negative bacterial infections are limited. Colistin based combination therapy remains the last option for such infections. The emerging resistance to colistin, especially the transferrable mcr-1 gene mediated resistance poses a global threat. Objectives: This study aims to determine the colistin susceptibility among the multi drug resistant (MDR) clinical isolates of Escherichia coli, Kebsiella pneumoniae and Pseudomonas aeruginosa and also to determine the prevalence of mcr-1 gene in t

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17

Khan, Asad U., Ayesha Sultan, Anju Tyagi, et al. "Amplification of mecA gene in multi-drug resistant Staphylococcus aureus strains from hospital personnel." Journal of Infection in Developing Countries 1, no. 03 (2007): 289–95. http://dx.doi.org/10.3855/jidc.366.

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Background: Antibiotic resistance is common among bacterial pathogens associated with both community acquired and nosocomial infections. In view of the present problem of drug resistance we investigated the prevalence of methicillin resistant Staphylococcus aureus (MRSA) and amplified the mecA gene in the isolates from the hand swabs of the hospital personnel. Methodology: The nuc gene was amplified to characterize these isolates at species level. The S. aureus isolates were analyzed for their susceptibility to different classes of antibiotics using the disk diffusion method. The spot inoculat

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18

Aljanaby, Ahmed Abduljabbar Jaloob, and Israa Abduljabbar Jaloob Aljanaby. "Prevalence of aerobic pathogenic bacteria isolated from patients with burn infection and their antimicrobial susceptibility patterns in Al-Najaf City, Iraq- a three-year cross-sectional study." F1000Research 7 (July 30, 2018): 1157. http://dx.doi.org/10.12688/f1000research.15088.1.

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Background: Burn infections are one of the most common serious illnesses caused by pathogens, mainly by both gram-negative and gram-positive bacteria. The aim of this study was to detect of the prevalence of multi-drug resistant and extended-spectrum β-lactamase-producing (ESBL) bacteria isolated from inpatients with burn infection and the antimicrobials sensitivity patterns of all bacterial isolates during three years. Methods: This cross-sectional study was performed in Al-Najaf Central Hospital in Al-Najaf City, Iraq from January 2015 to December 2017. A total of 295 burns swabs were collec

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Haji Saeed Akreyi, Waleed, Samira Younis Yousif, and Mahde Assafi. "Antibiotic Resistant and Plasmid Conjugative Study of Salmonella typhi." Jurnal Teknologi Laboratorium 7, no. 2 (2018): 1–7. http://dx.doi.org/10.29238/teknolabjournal.v7i2.134.

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The emergence of multi-drug resistant (MDR) bacteria has endangered the efficacy of antibiotics treatment of pathogenic bacteria worldwide. The aim of this research was to investigate the incidence of Salmonella enterica serovar Typhi in Duhok city, Iraq. Specimens of blood and stool were recruited from 267 patients. S. Typhi isolates were diagnosed depending on morphology, biochemical and serological tests. S. Typhi isolates were tested for their antibiotic resistance. Multi-drug resistant S. Typhi isolates were conjugated with E. coli HB101. The plasmid profile of transconjugants was investi

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M., Salahaldin Fathalla, N. A. Mahyudin, F. Mohamad Ghazali, and Y. Rukayadi. "Detection of enterotoxin gene (sea) and biofilm formation ability among multidrug resistant Staphylococcus aureus isolated from shawarma sandwich sold at selected kiosks in Klang Valley, Malaysia." Food Research 4, no. 4 (2020): 1234–44. http://dx.doi.org/10.26656/fr.2017.4(4).039.

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The occurrence of multi-drug resistant Staphylococcus aureus in food product of animal origin has increased the concern about their spread into the food supply chain. Presence of multidrug-resistant S. aureus in food products, including ready-to-eat foods imposes potential hazard for consumers. The objective of this research was to investigate the presence of multi-drug resistance of S. aureus in sixty ready-to-eat shawarma sandwiches. Agar-disc diffusion assay determined their resistance to 11 antibiotics. The sea and sed enterotoxin genes were detected by polymerase chain reaction method. Bi

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Nowakiewicz, Aneta, Przemysław Zięba, Sebastian Gnat, et al. "Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?" Research in Veterinary Science 128 (June 12, 2020): 49–58. https://doi.org/10.5281/zenodo.13440557.

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(Uploaded by Plazi for the Bat Literature Project) Bats are a poorly understood reservoir of pathogenic and multi-drug resistant microorganisms; therefore, the aim of the study was to analyze the presence of drug resistance among E. coli isolated from the species of bats occurring naturally in Poland. The strategy of isolation and identification of resistant strains from pooled and single-animal samples was based on selective media with cefotaxime, chloramphenicol, kanamycin and tetracycline, the use of the ADSRRS-fingerprinting method for genomic differentiation of isolates, and the classical

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Nowakiewicz, Aneta, Przemysław Zięba, Sebastian Gnat, et al. "Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?" Research in Veterinary Science 128 (June 7, 2020): 49–58. https://doi.org/10.5281/zenodo.13440557.

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(Uploaded by Plazi for the Bat Literature Project) Bats are a poorly understood reservoir of pathogenic and multi-drug resistant microorganisms; therefore, the aim of the study was to analyze the presence of drug resistance among E. coli isolated from the species of bats occurring naturally in Poland. The strategy of isolation and identification of resistant strains from pooled and single-animal samples was based on selective media with cefotaxime, chloramphenicol, kanamycin and tetracycline, the use of the ADSRRS-fingerprinting method for genomic differentiation of isolates, and the classical

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Nowakiewicz, Aneta, Przemysław Zięba, Sebastian Gnat, et al. "Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?" Research in Veterinary Science 128 (July 3, 2020): 49–58. https://doi.org/10.5281/zenodo.13440557.

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(Uploaded by Plazi for the Bat Literature Project) Bats are a poorly understood reservoir of pathogenic and multi-drug resistant microorganisms; therefore, the aim of the study was to analyze the presence of drug resistance among E. coli isolated from the species of bats occurring naturally in Poland. The strategy of isolation and identification of resistant strains from pooled and single-animal samples was based on selective media with cefotaxime, chloramphenicol, kanamycin and tetracycline, the use of the ADSRRS-fingerprinting method for genomic differentiation of isolates, and the classical

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24

Nowakiewicz, Aneta, Przemysław Zięba, Sebastian Gnat, et al. "Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?" Research in Veterinary Science 128 (July 10, 2020): 49–58. https://doi.org/10.5281/zenodo.13440557.

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(Uploaded by Plazi for the Bat Literature Project) Bats are a poorly understood reservoir of pathogenic and multi-drug resistant microorganisms; therefore, the aim of the study was to analyze the presence of drug resistance among E. coli isolated from the species of bats occurring naturally in Poland. The strategy of isolation and identification of resistant strains from pooled and single-animal samples was based on selective media with cefotaxime, chloramphenicol, kanamycin and tetracycline, the use of the ADSRRS-fingerprinting method for genomic differentiation of isolates, and the classical

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Nowakiewicz, Aneta, Przemysław Zięba, Sebastian Gnat, et al. "Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?" Research in Veterinary Science 128 (July 17, 2020): 49–58. https://doi.org/10.5281/zenodo.13440557.

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(Uploaded by Plazi for the Bat Literature Project) Bats are a poorly understood reservoir of pathogenic and multi-drug resistant microorganisms; therefore, the aim of the study was to analyze the presence of drug resistance among E. coli isolated from the species of bats occurring naturally in Poland. The strategy of isolation and identification of resistant strains from pooled and single-animal samples was based on selective media with cefotaxime, chloramphenicol, kanamycin and tetracycline, the use of the ADSRRS-fingerprinting method for genomic differentiation of isolates, and the classical

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Ali, Munim R., and Husam Ahmed AL-Nuaeyme. "Typing and Integron Distribution among Multi-Drug Resistance Escherichia coli." Journal for Research in Applied Sciences and Biotechnology 3, no. 1 (2024): 232–37. http://dx.doi.org/10.55544/jrasb.3.1.35.

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The study aimed, through the use of taxonomic associations, to find the genetic relationship between strains of Escherichia coli bacteria in 152 samples of infection symptoms. The results of the susceptibility test for 42 isolates showed that 8 isolates were sensitive to most antibiotics, while 12 isolates had moderate resistance, ranging from 5-8 antagonists, while 22 isolates were resistant to 9-12 antibiotics. Through the use of phylo-group profiling system it was found that the vast majority of Escherichia coli isolates under study have high virulence factors and possess large genomes by b

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De Silva, Benthotage Chamara Jayasankha, Sabrina Hossain, Pasan Sepala Dahanayake, Dae-Won Lee, Masimbule Vidanalage Kasun Sameera Wickramanayake, and Gang-Joon Heo. "Multi-drug resistant mesophilic aeromonads isolated from marketed scallops (Patinopecten yessoensis) harboring resistance genes." Fisheries & Aquatic Life 28, no. 1 (2020): 1–10. http://dx.doi.org/10.2478/aopf-2020-0001.

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AbstractAntimicrobial resistance properties of 32 Aeromonas strains isolated from fresh scallops (Patinopecten yessoensis (Jay)) marketed in Korea were assessed. All the Aeromonas spp., including A. salmonicida, were mesophilic and grew very well at 37°C. The isolates were tested for susceptibility to 19 antimicrobials belonging to eight antimicrobial classes. All isolates were multi-drug resistant, which means they were resistant to five or more antimicrobials. Higher resistance rates (≥ 50%) were observed for ampicillin, piperacillin, cephalothin, imipenem, meropenem, trimethoprim-sulfametho

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Sharma, Asmita, Purnakala Gurung, Sirjana Devkota, Sunita Ghimire, and Bipin Chapagain. "Fecal Carriage of Multi-drug Resistant Escherichia coli in Healthy Children: a Community-based Study." Journal of Health and Allied Sciences 12, no. 2 (2023): 17–22. http://dx.doi.org/10.37107/jhas.430.

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Introduction: Escherichia coli is enteric Gram-negative bacilli, earlier recognized as non-invasive commensal. Invasive strains of E. coli have been identified and are associated with a variety of human infections. Increasing drug resistance among E. coli has been reported. Multidrug resistance is the ability of an organism to resist at least one agent in three or more antimicrobial categories. The aim of this study was to detect fecal carriage of MDR E. coli isolates among healthy school children. Methods: A total of 139 stool samples were collected from Rastriya Secondary School, Puran

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Carruthers, Nicholas J., Sharon A. McClellan, Mallika Somayajulu, et al. "Effects of Glycyrrhizin on Multi-Drug Resistant Pseudomonas aeruginosa." Pathogens 9, no. 9 (2020): 766. http://dx.doi.org/10.3390/pathogens9090766.

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The effects of glycyrrhizin (GLY) on multi-drug resistant (MDR) systemic (MDR9) vs. ocular (B1045) Pseudomonas aeruginosa clinical isolates were determined. Proteomes of each isolate with/without GLY treatment were profiled using liquid chromatography mass spectrometry (LC-MS/MS). The effect of GLY on adherence of MDR isolates to immortalized human (HCET) and mouse (MCEC) corneal epithelial cells, and biofilm and dispersal was tested. Both isolates were treated with GLY (0.25 minimum inhibitory concentration (MIC), 10 mg/mL for MDR9 and 3.75 mg/mL for B1045) and subjected to proteomic analysis

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Khan, Salman, Priti Singh, Ms Rashmi, and Ashish Asthana. "Recent trend of multi-drug resistance in Pseudomonas aeruginosa." Bangladesh Journal of Medical Science 13, no. 4 (2014): 438–42. http://dx.doi.org/10.3329/bjms.v13i4.20591.

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Objective: Continuous emergence of resistance among Pseudomonas aeruginosa strains to common antimicrobial drugs have been documented world-wide. This study investigated the recent trend of antimicrobial resistance patterns of P. aeruginosa among the patients in mid & far western region of Nepal. Materials and Methods: The study was conducted on 917 patients with suspected P. aeruginosa infections, attending outpatient and inpatient departments of Nepalgunj Medical College and teaching Hospital, Banke, Nepal from September 2011 to January 2014. Specimens were collected from pus/wound, sput

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Marwa H. A. and A. Abdulrazzaq. "MOLECULAR CHARACTERIZATION OF MULTI-DRUG RESISTANCE ENTEROCOCCUS FAECALIS ISOLATED FROM MASTITIC COWS MILK." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 56, no. 3 (2025): 1021–28. https://doi.org/10.36103/p6j22287.

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The study objects were to assess Enterococcus faecalis prevalence in milk from mastitis infected cows, and access their antibiotic resistance as well as investigate their resistance genes. A total of 300 samples were tested during the period from February to May in 2022. The results of initial examination showed that only 81 isolates as E. species according to phenotypic criteria. Confirmatory test was conducted, the results showed that only 25 isolates by 8.3% E.faecalis isolates. Antimicrobial susceptibility test indicated high levels of contamination with multi-drug resistant E.faecalis of

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Oche, Dominic Agbo, Paul Ifeleke Oyegoke, Maryloveth Oluchukwu Akpudo, and Busayo Olalekan Olayinka. "Antibiotics Resistance Pattern of Staphylococcus aureus Isolated From In-patients of an Orthopaedic Hospital in North-Western Nigeria." International Journal of Epidemiologic Research 8, no. 4 (2021): 160–66. http://dx.doi.org/10.34172/ijer.2021.29.

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Background and aims: Staphylococcus aureus, an important pathogen in bone diseases, is a highly multi-drug resistant (MDR) bacterium. This study aimed to investigate the antibiotic resistance among S. aureus isolated from patients on admission in an orthopaedic hospital. Methods: In this cross-sectional research, 140 samples comprising urine samples, wound swabs, and nasal swabs were collected from 49 patients on admission. Samples were cultured and screened for S. aureus following standard procedures. Using the agar-disk diffusion method, the isolates were subjected to antibiotics susceptibil

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Bhatt, Chandra Prakash, Rina Baidya, Prakash Karki, et al. "Multi Drug Resistance Bacterial Isolates of Surgical Site Infection." Open Journal of Medical Microbiology 04, no. 04 (2014): 203–9. http://dx.doi.org/10.4236/ojmm.2014.44022.

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Dunya Jawad Ridha, Munim Radwan Ali, and Kifah Ahmed jassim. "Molecular analysis of multi –drug resistant acintobacter baumannii isolated in baghdad hospital." International Journal of Research in Pharmaceutical Sciences 10, no. 3 (2019): 1970–87. http://dx.doi.org/10.26452/ijrps.v10i3.1406.

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Qurum sense is regulatory systems that enable bacteria to expretion for a specific set of genes by making collective decisions and regulation of virulence factors of pathogenic Acintobacter baumannii, the prevalence of carbapenem resistance among (8) different antibiotic groups pattern. In the MDR index, all isolates showed high MDR, ranged from (6-21) antibiotics. MDR index is between (0.29-1.0).Quantitative biofilm production assay showed that 118/124(95.1%)of isolates were biofilm-formers. Detection of QS genes showed that (97.6%)121/124,(98.3%)122\124 and (4.8%)of isolates carried luxR, rh

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Allen, Joanne L., Nicholas P. Doidge, Rhys N. Bushell, Glenn F. Browning, and Marc S. Marenda. "Healthcare-associated infections caused by chlorhexidine-tolerant Serratia marcescens carrying a promiscuous IncHI2 multi-drug resistance plasmid in a veterinary hospital." PLOS ONE 17, no. 3 (2022): e0264848. http://dx.doi.org/10.1371/journal.pone.0264848.

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The bacterium Serratia marcescens can cause opportunistic infections in humans and in animals. In veterinary settings, the diversity, reservoirs and modes of transmission of this pathogen are poorly understood. The phenotypes and genotypes of Serratia spp. isolated from dogs, cats, horses, a bird and a rabbit examined at an Australian veterinary hospital between 2008 and 2019 were characterised. The isolates were identified as S. marcescens (n = 15) or S. ureilytica (n = 3) and were placed into four distinct phylogenetic groups. Nine quasi-clonal isolates associated with post-surgical complica

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V., Praveen Kumar, Sowjanya G., Archana A.R.K., and Swetha G. "Detection of Colistin Resistance Among Multi-Drug Resistant Gram-Negative Bacterial Isolates Isolated from Clinical Specimens of ICU Patients." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 619–25. https://doi.org/10.5281/zenodo.12573993.

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<strong>Introduction: </strong>Hospital‑associated infections caused by multidrug‑resistant (MDR) Gram negative bacteria (GNB), especially <em>Klebsiella</em> <em>pneumoniae, Acinetobacter baumannii, </em>and <em>Pseudomonas</em> <em>aeruginosa</em>, represent a growing problem worldwide Colistin is considered to be one of the last resort antibiotic of multi-drug resistant (MDR) gram-negative bacilli (GNB). The increase in colistin usage has resulted in the emergence of colistin resistance in GNB.<strong>Materials and Methods: </strong>The study included clin

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Akinyemi, Kabir’ O., Akintoye O. Coker, Daniel K. Olukoya, Akeeb O. Oyefolu, Eriwu P. Amorighoye, and Emmanuel O. Omonigbehin. "Prevalence of Multi-Drug Resistant Salmonella typhi among Clinically Diagnosed Typhoid Fever Patients in Lagos, Nigeria." Zeitschrift für Naturforschung C 55, no. 5-6 (2000): 489–93. http://dx.doi.org/10.1515/znc-2000-5-630.

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A total of 635 clinically diagnosed typhoid fever patients were bled from three different health institutions in the metropolis of Lagos, Nigeria over a period of 15 months, May 1997 to July 1998. Out of the total blood cultured, 101 (15.9% ) isolates of Salmonella species were isolated of which 68 (67.3% ) were S. typhi, 17 (16.8% ) and 16 (15.8% ) were S. paratyphi A and S. arizonae respectively. The overall isolation rate of S. typhi among patients is 10.7% , with most isolates 45.9% found among the severely-ill young adults, age group 1 6 -30 years. All isolates were subjected to anti-micr

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Kolaventi, Swarna Swetha, Lalatendu Moharana, Kothakonda Sairam, Lovish Dhingra, Takveer Singh, and Dipak Sethi. "Exploring Multi-Drug Resistance Mechanisms in MBL-Producing Gram-Negative Bacteria Isolated from Hospitalized Patients: A Phenotypic Analysis." Seminars in Medical Writing and Education 3 (December 31, 2024): 523. https://doi.org/10.56294/mw2024523.

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Multi-drug resistance (MDR) is a serious threat to the efficacy of therapeutic therapies for antimicrobial resistance (AMR), which is a worldwide health problem. Gram-negative bacteria that produce metallo-beta-lactamase (MBL) have become important sources of MDR, making it more difficult to treat infections in hospitalized patients. Objective: The Gram-negative bacteria (GNB) that produces MBL was isolated from hospitalized patients. Method: Fifty-five Acinetobacter baumannii isolates were analyzed in this Phenotypic Analysis. These isolates were taken from specimens of sputum that came from

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Nzube Favour, Ekpunobi, and Adeleye Adeyemi Isaac. "Phenotypic characterization of biofilm formation and efflux pump activity in multi-drug resistant staphylococcus species isolated from asymptomatic students." Journal of Microbiology & Experimentation 8, no. 6 (2020): 223–29. http://dx.doi.org/10.15406/jmen.2020.08.00313.

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Staphylococcus spp. are one of the major groups of bacterial commensals isolated from skin and mucous membranes. While a variety of Staphylococcal species are present on or in clinically normal individuals, some are also opportunistic pathogens and leading causes of community associated diseases in humans and animals worldwide. The objective of the study was to determine the antimicrobial susceptibility pattern, biofilm formation capability and efflux pump activity in Staphylococcus spp. isolated from nares and armpits of students. A total of 91 swab samples were collected from consenting micr

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Omar F. H. and A. H. Ibrahim. "THE PREVALENCE OF INTEGRON CLASS I AND II AMONG MULTI-DRUG RESISTANCE PRODUCING KLEBSIELLA pneumonia." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 51, no. 5 (2023): 619–29. http://dx.doi.org/10.36103/ijas.v51i5.1739.

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This study aimed to determine antibiotic resistance profiles and the distribution of Integron I, Integron II, and genes among uropathogenic Klebsiella pneumoniae isolated from patients suffering from urinary tract infection. The results revealed that one hundred and thirty-seven (91%) out of 150 clinical specimens were Klebsiella pneumoniae. The isolates (137 isolates) were given a higher percentage of resistance against Piperacillin (94.89%)and Rifampicin (93.43%) and the lowest resistance was with Meropenem (40.87%). According to PCR amplification for 15 isolates showed the proportion of cla

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Omar F. H. and A. H. Ibrahim. "THE PREVALENCE OF INTEGRON CLASS I AND II AMONG MULTI-DRUG RESISTANCE PRODUCING KLEBSIELLA pneumonia." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 54, no. 3 (2023): 619–29. http://dx.doi.org/10.36103/ijas.v54i3.1775.

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This study aimed to determine antibiotic resistance profiles and the distribution of Integron I, Integron II, and genes among uropathogenic Klebsiella pneumoniae isolated from patients suffering from urinary tract infection. The results revealed that one hundred and thirty-seven (91%) out of 150 clinical specimens were Klebsiella pneumoniae. The isolates (137 isolates) were given a higher percentage of resistance against Piperacillin (94.89%)and Rifampicin (93.43%) and the lowest resistance was with Meropenem (40.87%). According to PCR amplification for 15 isolates showed the proportion of cla

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Bassam, R. Almutairi* Mohd. Imran Emad Obaid Monadil H. M. Ali Abdulkhaliq J. Alsalman. "ASSESSMENT OF THE PREVALENCE OF MULTI-DRUG RESISTANCE ISOLATES OF KLEBSIELLA PNEUMONIAE AMONG THE PATIENTS AT NORTHERN AREA ARMED FORCES HOSPITAL (NAAFH) OF THE EASTERN REGION OF SAUDI ARABIA." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1511–19. https://doi.org/10.5281/zenodo.815368.

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The objective of this study was to assess the prevalence of multi-drug resistance isolates of Klebsiella pneumoniae among the patients at Northern Area Armed Forces Hospital (NAAFH) of the Eastern region of Saudi Arabia. This retrospective, chart review observational study was conducted from February 1, 2016 to February 29, 2016 at Northern Area Armed Forces Hospital (NAAFH), a 330-bed community general hospital located in the Eastern region of Saudi Arabia. A total of 870 isolates were identified in 298 patients (3 isolates per patient involving multiple sites). It was observed that the risk

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JAPONI, SARA, AZIZ JAPONI, SHOREH FARSHAD, AHYA ABDI ALI, and MARZIEH JAMALIDOUST. "Association between Existence of Integrons and Multi-Drug Resistance in Acinetobacter Isolated from Patients in Southern Iran." Polish Journal of Microbiology 60, no. 2 (2011): 163–68. http://dx.doi.org/10.33073/pjm-2011-023.

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Nosocomial infections caused by multi-drug resistant Acinetobacter pose a serious problem in many countries. This study aimed at determining the antibiotic susceptibility patterns and prevalence of different classes of integrons in isolated Acinetobacter. In addition, the association between production of specific bands in PCR assay and magnitude of multi-drug resistance was investigated. In total, 88 Acinetobacter strains were isolated from patients from October 2008 through September 2009. The Minimal inhibitory concentration (MIC) of 12 antibiotics conventionally used in clinics against the

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Meroni, Gabriele, Joel F. Soares Filipe, Lorenzo Drago, and Piera A. Martino. "Investigation on Antibiotic-Resistance, Biofilm Formation and Virulence Factors in Multi Drug Resistant and Non Multi Drug Resistant Staphylococcus pseudintermedius." Microorganisms 7, no. 12 (2019): 702. http://dx.doi.org/10.3390/microorganisms7120702.

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Staphylococcus pseudintermedius is a commensal bacterium frequently isolated from canine skin and recognized as a zoonotic agent especially for dog-owners. This study focused on (a) the antibiotic-resistance phenotypes; (b) the ability to produce biofilm (slime); and (c) the dissemination of virulence factors in S. pseudintermedius strains. Seventy-three S. pseudintermedius strains were screened for antibiotic-resistance against 22 different molecules by means of Kirby-Bauer assay. The ability to produce biofilm was investigated using the microtiter plate assay (MtP) and the amplification of i

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Rahman, M. A., A. K. M. A. Rahman, M. A. Islam, and M. M. Alam. "ANTIMICROBIAL RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM MILK, BEEF AND CHICKEN MEAT IN BANGLADESH." Bangladesh Journal of Veterinary Medicine 15, no. 2 (2018): 141–46. http://dx.doi.org/10.3329/bjvm.v15i2.35525.

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Food-borne pathogens causing infections and intoxications can affect everyone. Escherichia (E) coli is one of the major food borne bacterial pathogens. This study was conducted to investigate the prevalence of E. coli in milk, chicken meat and beef and to determine the multi-drug resistance profile of E. coli in Mymensingh district, Bangladesh. A total of 169 samples including milk (n=108), chicken meat (n=51) and beef (n=10) were collected from Bangladesh Agricultural University (BAU) dairy farm, American dairy farm, Gazipur and retail markets of municipal area during July 2016 to June 2017.

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Shrestha, Rajeev, Navin Adhikari, Sailesh Pradhan, et al. "Antimicrobial Resistance in Typhoidal Salmonella in Nepal: Surveillance for Enteric Fever, 2016-2019." Journal of Nepal Health Research Council 19, no. 1 (2021): 162–69. http://dx.doi.org/10.33314/jnhrc.v19i1.3497.

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Background: Enteric fever (caused by Salmonella enterica) has been associated with poor hygiene and is endemic in the South-Asian countries. The increase in resistance to first line antimicrobials has been observed, while the emergence of multi/extremely drug resistance cases have been identified in several countries. The objective of this study is to analyze the current trend of antimicrobial resistance in Salmonella isolates in Nepal, and to identify the status of multi- and extremely- drug resistant isolates.Methods: We recruited individuals at study hospitals with suspected enteric fever b

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Nguyen, Hieu Duc, Son Thai Nguyen, Van Thi Thu Ha, Minh Ngoc Nghiem, and Thuy Thi Bich Vo. "Expression of some resistant genes on six Elizabethkingia spp. strains isolated in Vietnam." Journal of Public Health and Diseases 3, no. 2 (2020): 35–42. http://dx.doi.org/10.31248/jphd2020.063.

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This study focused on the assessment of the multiantibiotic-resistance and gene expression associated with multi-drug resistance in Elizabethkingia. Six Elizabethkingia spp. strains were isolated from patient samples, and the antibiotic-resistance of the six isolates with all 14 tested antibiotics was confirmed. MacConkey subculture and 16S rRNA sequencing were used to identify the six isolates as; one Elizabethkingia meningoseptica (E. meningoseptica) isolate, and five E. anophelis isolates. Seven genes including four-resistant genes (blaB, blaCME, ant6, lolD and catB and two antibiotics targ

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Mann, Avantika, J. S. Rana, Kiran Nehra, Gaurav Sharma, and Twinkle . "Prevalence of Multi-Drug-Resistant bacterial strains in agricultural soils of Haryana, India." Research Journal of Biotechnology 16, no. 8 (2021): 61–71. http://dx.doi.org/10.25303/168rjbt6121.

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Due to continuous misuse or overuse of antibiotics for various purposes in farm animals, the present century has witnessed a rapid increase in the prevalence of multi-drug-resistant bacterial strains specifically in the soil ecosystems throughout the world. In view of this significant fact, the present study was designed to assess the prevalence and spread of antibiotic-resistant-bacteria in agricultural soils of Haryana State in India. For this, a total of 135 bacteria were isolated from the soils of organic and conventional farms spread throughout the State. All the isolates were tested for

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Elhameed, Alaa, Samy Khaliel, and Helmy Torky. "Characterization of Klebsiella pneumoniae isolated from Contaminated Sheep and Goat Meat at Matrouh Governorate and Its Antibiotic Resistance." Alexandria Journal of Veterinary Sciences 79, no. 1 (2023): 37. http://dx.doi.org/10.5455/ajvs.166298.

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The study of Klebsiella pneumoniae as a food born pathogen that isolated from sheep and goat meat at Matrouh Governorate, and tracking the extent of its resistance to various antibiotics, is considered the first study at Matrouh Governorate. Out of 48 meat samples, 6 (12.5%) were positive for Klebsiella pneumoniae subspecies pneumoniae by PCR. All Klebsiella pneumoniae isolates (100%) showed presence of fim H and aerobactin genes. All isolates showed resistance to at least 3 different classes of antibiotics, so, considered as multi drug resistant (MDR) or pan-drug resistant. The 2 pan-drug res

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Ghaderi, Hossein, Abdolmajid Mohammadzadeh, Mohamadreza Pajohi-alamoti, Ali Sadeghi-nasab, Pezhman Mahmoodi, and Ali Goudarztalejerdi. "Molecular Characterization and Antibiotic Resistance Profile of Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated From Milk Samples of Apparently Healthy Cattle in Hamedan, Iran." Avicenna Journal of Clinical Microbiology and Infection 9, no. 4 (2022): 165–70. http://dx.doi.org/10.34172/ajcmi.2022.3395.

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Background: Staphylococcus aureus, as a major food-borne pathogen, is the most commonly isolated bacterium from bovine mastitis. However, some S. aureus strains exhibit a high rate of antibiotic resistance, among which, methicillin-resistant S. aureus (MRSA) is very important. The present study was conducted to isolate, characterize, and determine the antibiotic resistance profile of MRSA strains in milk. Methods: Staphylococcus aureus strains were isolated and identified from 415 milk samples collected from apparently healthy cattle in Hamedan province, Iran. Molecular characteristics of the

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