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Dissertations / Theses on the topic 'Multi Imaging Modality'

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1

Kastis, Georgios. "Multi-modality imaging of small animals." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/289830.

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Over the last few years there has been a great demand for noninvasive, dedicated, small-animal imaging systems for biomedical research applications. In this dissertation we will discuss the development and performance of two gamma-ray systems and a dual modality CT/SPECT system. Initially we introduce FASTSPECT, a stationary, scintillator-based, single-photon emission computed tomography (SPECT) system that was originally built as a brain imager. We discuss its transformation into a small-animal imaging system and validate its performance by presenting high-resolution images of phantoms and an
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2

Gerbaud, Edouard. "Multi-modality imaging of atherosclerotic plaque using optical coherence tomography." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0132/document.

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Les technologies d'imagerie intravasculaire c’est à dire l’échographie endo-coronaire (IVUS)et la tomographie par cohérence optique (IV-OCT) sont des outils précieux pour aider audiagnostic de la plaque d’athérosclérose et guider les gestes thérapeutiques.Le chapitre 1 présente les inconvénients de la coronarographie dans la pratique clinique.Dans plusieurs circonstances, l’IVUS et l’OCT ont clairement une valeur supplémentaire quandils sont utilisés comme un outil diagnostique en cas d'ambiguïtés angiographiques. Nousavons récemment rapporté la première observation utilisant l’OCT pour décrir
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Wall, Richard Andrew. "Multi-Modality Endoscopic Imaging for the Detection of Colorectal Cancer." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/301761.

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Optical coherence tomography (OCT) is an imaging method that is considered the optical analog to ultrasound, using the technique of optical interferometry to construct two-dimensional depth-resolved images of tissue microstructure. With a resolution on the order of 10 μm and a penetration depth of 1-2 mm in highly scattering tissue, fiber optics-coupled OCT is an ideal modality for the inspection of the mouse colon with its miniaturization capabilities. In the present study, the complementary modalities laser-induced fluorescence (LIF), which offers information on the biochemical makeup of the
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4

Baiocco, Serena <1989&gt. "Analysis and measurement of tumour heterogeneity through multi-modality imaging." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/9045/1/PhD_Thesis_Serena_Baiocco_14_02_2019.pdf.

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Cancer is among the leading causes of mortality worldwide. The need for more effective functional biomarkers as well as the awareness of the complexity of tumour biology, which reflects the tissue heterogeneity, have prompted the use of imaging modalities able to detect its biological aspects. Dynamic Contrast Enhanced-Computed Tomography (DCE-CT), Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) have shown promising results. However, there is still need for proper reliability analyses and development of more quantitative approaches, involving the evaluation of tumour he
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5

Longo, M. "MULTI MODALITY IMAGING APPROACHES TO INJECTION-SITE SARCOMA IN CATS." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/487980.

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The aim of this study was to investigate different diagnostic imaging approaches for Injection-Site Sarcomas in cats (ISS) and their mutual relationships with the surrounding tissues between December 2014 and October 2016. In the literature there is a lack of anatomical references about the interscapular region of the cat, with very few publications displaying the musculoskeletal anatomy in transverse sections. Computed Tomography (CT) has been proven to be useful in the staging process of feline patients affected by ISS, not only for correct estimation of the volumetric balance of the tumour
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6

Kumar, Ashnil. "A graph-based approach for the retrieval of multi-modality medical images." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/9343.

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Medical imaging has revolutionised modern medicine and is now an integral aspect of diagnosis and patient monitoring. The development of new imaging devices for a wide variety of clinical cases has spurred an increase in the data volume acquired in hospitals. These large data collections offer opportunities for search-based applications in evidence-based diagnosis, education, and biomedical research. However, conventional search methods that operate upon manual annotations are not feasible for this data volume. Content-based image retrieval (CBIR) is an image search technique that uses automat
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7

Conway, Joy Helen. "The assessment of intra-pulmonary deposition of aerosols using multi-modality imaging." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242562.

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8

Youniss, Fatma. "MULTI – MODALITY MOLECULAR IMAGING OF ADOPTIVE IMMUNE CELL THERAPY IN BREAST CANCER." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3323.

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Cancer treatment by adoptive immune cell therapy (AIT) is a form of immunotherapy that relies on the in vitro activation and/or expansion of immune cells. In this approach, immune cells, particularly CD8+ T lymphocytes, can potentially be harvested from a tumor-bearing patient, then activated and/or expanded in vitro in the presence of cytokines and other growth factors, and then transferred back into the same patient to induce tumor regression. AIT allows the in vitro generation and activation of T-lymphocytes away from the immunosuppressive tumor microenvironment, thereby providing optimum c
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9

Thornton, Matthew. "Frequency Partition Techniques of FMCW Radar Imaging Systems for MIMO Multi-Static Array Modality." International Foundation for Telemetering, 2016. http://hdl.handle.net/10150/624193.

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The modalities of many imaging applications have been advancing toward the MIMO format for improved efficiency. This paper presents an approach to the implementation of the MIMO operating modality for FMCW radar imaging systems with multi-element data-acquisition arrays. The unique characteristics of the software-defined step-frequency FMCW imaging systems enable the simple and precise orthogonalization procedure through direct spectral partitioning. This paper includes the description of the data-acquisition hardware of an eighttransceiver radar imaging system, imaging formation algorit
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10

Jones, Michael Greystock. "An investigation of the potential of multi-modality imaging in three dimensional thick tissue microscopy." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387965.

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11

Kalemis, Antonios. "Signal detection in multi-modality medical imaging : comparison of different conditions using voxelwise statistical techniques." Thesis, Institute of Cancer Research (University Of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415087.

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12

Schafer, Rachel Lynn. "Mammary Window Chamber Model: A Platform For Multi-Modality Cancer Imaging And Dynamic Oxygenation Assessment." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/556436.

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Window chamber models have served as a tool for optically visualizing a tissue environment over time. Their use throughout the years has furthered the study of cancer. However, optical imaging techniques utilized with the model are limited in the depth from which light can penetrate and signal can be received. Further, ectopic placement of a xenograft in a model animal may modify the relevancy of findings by altering the normal environmental conditions. In the first section of the dissertation, improvements on the traditional window chamber model are described in the context of enabling multip
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13

Gurjarpadhye, Abhijit Achyut. "Dynamic Non-Destructive Monitoring of Bioengineered Blood Vessel Development within a Bioreactor using Multi-Modality Imaging." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/51359.

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Regenerative medicine involves formation of tissue or organ for replacement of a wounded or dysfunctional tissue. Healthy cells extracted from the patient are expanded and are seeded on a three-dimensional biodegradable scaffold. The structure is then placed in a bioreactor and is provided with nutrients for the cells, which proliferate and migrate throughout the scaffold to eventually form a desired to tissue that can be transplanted into the patient\'s body.  Inability to monitor this complex process of regeneration in real-time makes control and optimization of this process extremely diffic
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14

Halaweish, Ahmed Fathi. "Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/2711.

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Hyperpolarized 3Helium (HP 3He) magnetic resonance imaging (MRI) has provided considerable insights into the anatomical structures and localized physiological phenomenon involved in pulmonary ventilation. The increasing mortality rates of pulmonary diseases such as COPD, gives rise to the need for sensitive and regional assessments of early disease conditions in attempts to decrease mortality and improve lifestyles. Evaluation of the HP 3He MRI diffusion weighted measurements of lung microstructure, demonstrated a statistically significant relationship between microstructure expansion and degr
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15

Wang, Chengjia. "Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22918.

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Different medical imaging modalities provide complementary anatomical and functional information. One increasingly important use of such information is in the clinical management of cardiovascular disease. Multi-modality data is helping improve diagnosis accuracy, and individualize treatment. The Clinical Research Imaging Centre at the University of Edinburgh, has been involved in a number of cardiovascular clinical trials using longitudinal computed tomography (CT) and multi-parametric magnetic resonance (MR) imaging. The critical image processing technique that combines the information from
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AKBAR, MUHAMMAD USMAN. "Deep Learning Approaches Targeting Radiological Images." Doctoral thesis, Università degli studi di Genova, 2022. http://hdl.handle.net/11567/1069387.

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Artificial Intelligence (AI) algorithms have remarkably improved their performance in the recent years in various domains, thanks to the introduction of deep learning approaches. Indeed they have shown a tremendous potential when solving tasks involving image analysisThe problem of deep learning is its requirement for huge datasets, nonetheless, DL approaches have proved to be helpful in the domain of medical imaging as well. Automated segmentation and classification in different biomedical tasks have proven to be faster and more cost effective. In this thesis we study deep learning approa
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17

Le, Pogam Adrien. "Correction des effets de volume partiel en tomographie d'émission." Thesis, Tours, 2010. http://www.theses.fr/2010TOUR3304/document.

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Ce mémoire est consacré à la compensation des effets de flous dans une image, communément appelés effets de volume partiel (EVP), avec comme objectif d’application l’amélioration qualitative et quantitative des images en médecine nucléaire. Ces effets sont la conséquence de la faible résolutions spatiale qui caractérise l’imagerie fonctionnelle par tomographie à émission mono-photonique (TEMP) ou tomographie à émission de positons (TEP) et peuvent être caractérisés par une perte de signal dans les tissus présentant une taille comparable à celle de la résolution spatiale du système d’imagerie,
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18

Hett, Kilian. "Multi-scale and multimodal imaging biomarkers for the early detection of Alzheimer’s disease." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0011/document.

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La maladie d’Alzheimer est la première cause de démence chez les personnes âgées. Cette maladie est caractérisée par un déclin irréversible des fonctions cognitives. Les patients atteints par la maladie d’Alzheimer ont de sévères pertes de mémoire et ont de grandes difficultés à apprendre de nouvelles informations ce qui pose de gros problèmes dans leur vie quotidienne. À ce jour, cette maladie est diagnostiquée après que d’importantes altérations des structures du cerveaux apparaissent. De plus, aucune thérapie existe permettant de faire reculer ou de stopper la maladie. Le développement de n
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19

Orczyk, Clément. "Modélisation du cancer de la prostate par l'imagerie : détection, stratification, planning thérapeutique et suivi en 3D d'une thérapie focale basés sur le recalage-fusion d'image en multi modalité." Thesis, Normandie, 2017. http://www.theses.fr/2017NORMC405/document.

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Dénommée multiparamétrique par adjonction de séquences fonctionnelle aux conventionnelles, L’IRM de prostate a montré ses performances pour la détection du cancer de prostate par un score radiologique visuel, subjectif. D’autres applications sont en cours d’investigations comme la stratification, le planning thérapeutique ou encore le suivi oncologique.La première partie s’attache à décrire, élaborer et appliquer une méthodologie de recalage non rigide en 3D entre l’histologie du spécimen de prostatectomie totale et les différentes séquences de l’IRMmp. Après avoir capturé une déformation et u
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20

Varoquaux, Arthur Damien. "Evaluation clinique et expérimentale des nouvelles modalités d'imagerie dans la prise en charge des néoplasies ORL notamment par la TEP/IRM." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5058.

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En oncologie ORL, l'imagerie multiparamétrique est utilisée par un nombre grandissant d'équipes. Parmi les bio-marqueurs, la captation normalisée du fluoro-désoxyglucose (SUV-FDG) en tomoscintigraphie par émission de positons (TEP) et la restriction de la diffusion en IRM (DWI-MRI) sont les plus utilisées.L'IRM couplée à la TEP (TEP/IRM) est une nouveauté qui permet une diminution très significative des doses d'irradiation délivrées par rapport à la TEP/TDM. Nous adressons notre première expérience concernant l'aspect en diffusion et en TEP/IRM dans la surveillance des patients après radio-chi
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21

Chiang, Yun-Chen, and 江昀真. "Multi-modality functional imaging of opioid intervention in nociception." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/47065798850942855635.

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碩士<br>國立臺灣大學<br>醫學工程學研究所<br>97<br>Due to the complexity of the pain processing in brain, understanding the antinociceptive modulation within brain areas raises a need for simultaneously detecting the spatiotemporal patterns of neuronal activities. In the last decades, arising consciousness of pain using in vivo imaging techniques have dramatically increased. Functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) are the most commonly used techniques providing non-invasive, in vivo measurement of the cerebral hemodynamics as well as molecular processes. However, the
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22

Chen, Li-Yen, and 陳立言. "Image registration for US/PET multi-modality small animal imaging." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/66814091619427361180.

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碩士<br>國立臺灣大學<br>電機工程學研究所<br>94<br>Small animal models have been used extensively in disease research, genomics research, drug development, and developmental biology. A non-invasive, small animal imaging system with high spatial resolution and high sensitivity is beneficial to the research above mentioned. On the other hand, multi-modality medical imaging can provide complementary image information and is of further importance. The purpose of this research is thus to combine high-frequency ultrasonic imaging and micro-PET imaging. To achieve this goal, image registration is a critical stag. In
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23

Jhan, Jhen-Wei, and 詹鎮瑋. "Integrated Multi-modality, Multiphoton Microscopy for Label-free Tissue Imaging." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/00162842885882015130.

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碩士<br>國立交通大學<br>應用化學系所<br>97<br>Multiphoton microscopy has found wide-spreading biomedical applications due to its capability in producing three dimensional images of optically thick specimens with great contrast and high spatial resolution. Among various kinds of multiphoton microscopy, two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) are the two most extensively employed modalities in imaging biomedical samples. TPEF has been applied in live cell imaging through the excitation of intracellular auto-fluorescent components whereas SHG, arising only from media lacking
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24

Wang, Youmin 1986. "Miniature laser scanning micro-endoscopes : multi-modality imaging system and biomedical applications." 2013. http://hdl.handle.net/2152/20792.

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Cancer is a world menace. After years of endeavor seeking the end of it, people started to realize that no matter how powerful the therapy could be, detection at early stage is always a cheaper, easier and more successful solution compared with curative methods for cancer developed onto its advanced stage. However, relatively few early-detection approaches have proven sufficiently effective and practical for mass use as a point-of-care tool. An early-cancer screening tool integrating the desired features of sensitive, informative, portable, and cost-effective is in need for the doctors. The
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25

Liao, Ai-Ho, and 廖愛禾. "Techniques and Applications of Multi-modality Small Animal Imaging in Cancer Research." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/76811032167876883587.

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博士<br>國立臺灣大學<br>電機工程學研究所<br>97<br>Small-animal models are used extensively in disease research, genomics research, drug development, and developmental biology. The development of noninvasive small-animal imaging techniques with adequate spatial resolution and sensitivity is therefore of prime importance. In particular, multimodality small-animal imaging can provide complementary information. This paper presents a method for registering high-frequency ultrasonic (microUS) images with small-animal positron-emission tomography (microPET) images. Registration is performed using six external multim
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"Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging." Master's thesis, 2018. http://hdl.handle.net/2286/R.I.50603.

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abstract: Hypoxia is a pathophysiological condition which results from lack of oxygen supply in tumors. The assessment of tumor hypoxia and its response to therapies can provide guidelines for optimization and personalization of therapeutic protocols for better treatment. Previous research has shown the difficulty in measuring hypoxia anatomically due to its heterogenous nature. This makes the study of hypoxia through various imaging modalities and mapping techniques crucial. The potential of hypoxia targeting T1 contrast agent GdDO3NI in generating hypoxia maps has been studied earlier. In th
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Pang, Ian. "Design and Characterization of a Multi-modality Phantom for Contrast Enhanced Ultrasound and Magnetic Resonance Imaging." Thesis, 2011. http://hdl.handle.net/1807/29597.

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Multi-modality imaging is a possible solution for overcoming individual modality limitations. With the use of modality specific contrast agents, contrast-enhanced multi-modality imaging may provide a more comprehensive evaluation of tumour characteristics. This may be possible by combining ultrasound and magnetic resonance imaging, whose contrast agents behave differently within the microvasculature. A novel, microvascular, and leaky phantom is presented that permits ultrasound contrast agents to remain entirely within the mimicking vascular compartment while the magnetic resonance contrast
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28

"Multi-modality imaging in planning patients with head and neck squamous cell carcinomas : myths and reality." Université catholique de Louvain, 2005. http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-02192005-191120/.

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29

Moosvi, Firas. "Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo." Thesis, 2012. http://hdl.handle.net/1807/33669.

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The use of complementary non-invasive imaging modalities has been proposed to track disease progression, particularly cancer, while simultaneously evaluating therapeutic efficacy. A major obstacle is a limited ability to compare parameters obtained from different modalities, especially those from exogenous contrast agents or tracers. We hypothesize that combining Magnetic Resonance Imaging (MRI) and Ultrasound (US) will improve characterization of the tumour microenvironment. In this study, we describe a co-registration apparatus that facilitates the acquisition of a priori co-registered MR an
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Shih, Yao-Chia, and 石曜嘉. "Altered Structural and Functional Connectivity and Its Clinical Relevance of Mesial Temporal Lobe Epilepsy: A Multi-Modality Magnetic Resonance Imaging Study." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/y34y9k.

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博士<br>國立臺灣大學<br>醫學工程學研究所<br>107<br>Introduction: Many patients with mesial temporal lobe epilepsy with mesial temporal sclerosis (MTLE-MTS) fail to benefit from adequate medication for seizure control. There are many patients with intractable MTLE-MTS who have undergone resection of the epileptogenic focus, such as the hippocampus, but will continue to have seizures after surgery. Recent neuroimaging studies have indicated that in MTLE-MTS patients, in addition to mesial temporal lobe sclerosis, the brain regions outside the mesial temporal lobe also have structural and functional alterations;
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31

Pathan, FK. "The role of advanced cardiovascular imaging in the management of the new cardiovascular epidemics of old age." Thesis, 2019. https://eprints.utas.edu.au/31902/1/Pathan_whole_thesis.pdf.

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\({Background}\) The ageing population, greater survival following acute myocardial infarction and a greater prevalence of risk factors have all contributed to the emerging epidemics of Atrial Fibrillation (AF) and Heart Failure with Preserved Ejection Fraction (HFpEF). At the same time, the landscape of cardiovascular imaging has shifted from echocardiography alone to one of multi-modality imaging. The combination of these developments has contributed to an increase in inappropriate use of cardiac investigations which, in its own right is an iatrogenic cardiovascular epidemic. An understandin
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