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Relevant bibliographies by topics / Multi-organ-on-chip

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Academic literature on the topic 'Multi-organ-on-chip'

Author: Grafiati

Published: 25 May 2024

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Journal articles on the topic "Multi-organ-on-chip"

1

Zuchowska, Agnieszka, and Sandra Skorupska. "Multi-organ-on-chip approach in cancer research." Organs-on-a-Chip 4 (December 2022): 100014. http://dx.doi.org/10.1016/j.ooc.2021.100014.

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Lungu, Iulia Ioana, and Alexandru Mihai Grumezescu. "Microfluidics – Organ-on-chip." Biomedical Engineering International 1, no. 1 (2019): 2–8. http://dx.doi.org/10.33263/biomed11.002008.

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This review is an introduction into the world of organ-on-chip models. By briefly explaining the concept of microfluidics and ‘lab-on-chip’, the main focus is on organs-on-chip and body-on-a-chip. The usual method to test the toxicity of a drug is through animal testing. However, the results do not always correlate to humans. In order to avoid animal testing, but also attain useful results, human-derived cell cultures using microfluidics have gained attention. Among all the different types of organ-on-chip devices, this review focuses on three distinct organs: heart, skin and liver. The main r

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3

Palaninathan, Vivekanandan, Vimal Kumar, Toru Maekawa, et al. "Multi-organ on a chip for personalized precision medicine." MRS Communications 8, no. 03 (2018): 652–67. http://dx.doi.org/10.1557/mrc.2018.148.

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4

Kim, Jinyoung, Junghoon Kim, Yoonhee Jin, and Seung-Woo Cho. "In situ biosensing technologies for an organ-on-a-chip." Biofabrication 15, no. 4 (2023): 042002. http://dx.doi.org/10.1088/1758-5090/aceaae.

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Abstract The in vitro simulation of organs resolves the accuracy, ethical, and cost challenges accompanying in vivo experiments. Organoids and organs-on-chips have been developed to model the in vitro, real-time biological and physiological features of organs. Numerous studies have deployed these systems to assess the in vitro, real-time responses of an organ to external stimuli. Particularly, organs-on-chips can be most efficiently employed in pharmaceutical drug development to predict the responses of organs before approving such drugs. Furthermore, multi-organ-on-a-chip systems facilitate t

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5

Vivas, Aisen, Albert van den Berg, Robert Passier, Mathieu Odijk, and Andries D. van der Meer. "Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-on-chips." Lab on a Chip 22, no. 6 (2022): 1231–43. http://dx.doi.org/10.1039/d1lc00999k.

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Translational Organ-on-Chip Platform (TOP) is a multi-institutional effort to develop an open platform for automated organ-on-chip culture that actively facilitates the integration of components from various developers.

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6

Satoh, T., S. Sugiura, K. Shin, et al. "A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform." Lab on a Chip 18, no. 1 (2018): 115–25. http://dx.doi.org/10.1039/c7lc00952f.

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7

Boeri, Lucia, Luca Izzo, Lorenzo Sardelli, Marta Tunesi, Diego Albani, and Carmen Giordano. "Advanced Organ-on-a-Chip Devices to Investigate Liver Multi-Organ Communication: Focus on Gut, Microbiota and Brain." Bioengineering 6, no. 4 (2019): 91. http://dx.doi.org/10.3390/bioengineering6040091.

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The liver is a key organ that can communicate with many other districts of the human body. In the last few decades, much interest has focused on the interaction between the liver and the gut microbiota, with their reciprocal influence on biosynthesis pathways and the integrity the intestinal epithelial barrier. Dysbiosis or liver disorders lead to0 epithelial barrier dysfunction, altering membrane permeability to toxins. Clinical and experimental evidence shows that the permeability hence the delivery of neurotoxins such as LPS, ammonia and salsolinol contribute to neurological disorders. Thes

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8

Loskill, Peter, Thiagarajan Sezhian, Kevin M. Tharp, et al. "WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue." Lab on a Chip 17, no. 9 (2017): 1645–54. http://dx.doi.org/10.1039/c6lc01590e.

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9

Zhao, Yi, Ranjith Kankala, Shi-Bin Wang, and Ai-Zheng Chen. "Multi-Organs-on-Chips: Towards Long-Term Biomedical Investigations." Molecules 24, no. 4 (2019): 675. http://dx.doi.org/10.3390/molecules24040675.

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With advantageous features such as minimizing the cost, time, and sample size requirements, organ-on-a-chip (OOC) systems have garnered enormous interest from researchers for their ability for real-time monitoring of physical parameters by mimicking the in vivo microenvironment and the precise responses of xenobiotics, i.e., drug efficacy and toxicity over conventional two-dimensional (2D) and three-dimensional (3D) cell cultures, as well as animal models. Recent advancements of OOC systems have evidenced the fabrication of ‘multi-organ-on-chip’ (MOC) models, which connect separated organ cham

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10

Sun, Qiyue, Jianghua Pei, Qinyu Li, Kai Niu, and Xiaolin Wang. "Reusable Standardized Universal Interface Module (RSUIM) for Generic Organ-on-a-Chip Applications." Micromachines 10, no. 12 (2019): 849. http://dx.doi.org/10.3390/mi10120849.

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The modular-based multi-organ-on-a-chip enables more stable and flexible configuration to better mimic the complex biological phenomena for versatile biomedical applications. However, the existing magnetic-based interconnection modes are mainly realized by directly embedding and/or fixing magnets into the modular microfluidic devices for single use only, which will inevitably increase the complexity and cost during the manufacturing process. Here, we present a novel design of a reusable standardized universal interface module (RSUIM), which is highly suitable for generic organ-on-chip applicat

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