Relevant bibliographies by topics / Multicenter clinical trial

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Multicenter clinical trial'

Author: Grafiati
Published: 7 July 2024
Last updated: 31 July 2025

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Journal articles on the topic "Multicenter clinical trial"

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Pucker, Andrew D., Nicole Derthick, and Lanita Scott. "Running the enrollment numbers on ophthalmic clinical trials in the United States." Optometry and Vision Science 101, no. 8 (2024): 523–29. http://dx.doi.org/10.1097/opx.0000000000002174.

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SIGNIFICANCE This is one of the first reports to summarize the enrollment metrics for ophthalmology trials completed in the United States (US). PURPOSE This study aimed to describe US ophthalmology clinical trial enrollment metrics to facilitate planning and budgeting of US Food and Drug Administration–regulated ophthalmological drugs trials. METHODS A GlobalData PLC search was conducted on or before February 27, 2024, to evaluate the clinical trial landscape for completed ophthalmology clinical trials conducted in the US. The primary search contained only the term “ophthalmology,” which was r
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Justice, Jamie N., George A. Kuchel, Nir Barzilai, and Stephen Kritchevsky. "BIOMARKER STRATEGIES FOR GEROSCIENCE-GUIDED CLINICAL TRIALS." Innovation in Aging 3, Supplement_1 (2019): S745—S746. http://dx.doi.org/10.1093/geroni/igz038.2731.

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Abstract Significant progress in the biology of aging and animal models supports the geroscience hypothesis: by targeting biological aging the onset of age-related diseases can be delayed. Geroscience investigators will test this hypothesis in a multicenter clinical trial, to determine if interventions on biological aging processes can prevent accumulation of multiple age-related diseases and aging phenotypes in older adults. Prodigious activity is underway to develop markers of biological aging, but currently there is no aging biomarker consensus to support geroscience-guided clinical trial o
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Nishio, Teiji, Mitsuhiro Nakamura, Hiroyuki Okamoto, et al. "An overview of the medical-physics-related verification system for radiotherapy multicenter clinical trials by the Medical Physics Working Group in the Japan Clinical Oncology Group–Radiation Therapy Study Group." Journal of Radiation Research 61, no. 6 (2020): 999–1008. http://dx.doi.org/10.1093/jrr/rraa089.

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Abstract The Japan Clinical Oncology Group–Radiation Therapy Study Group (JCOG-RTSG) has initiated several multicenter clinical trials for high-precision radiotherapy, which are presently ongoing. When conducting multi-center clinical trials, a large difference in physical quantities, such as the absolute doses to the target and the organ at risk, as well as the irradiation localization accuracy, affects the treatment outcome. Therefore, the differences in the various physical quantities used in different institutions must be within an acceptable range for conducting multicenter clinical trial
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Chung, Kevin C., and Jae W. Song. "A Guide to Organizing a Multicenter Clinical Trial." Plastic and Reconstructive Surgery 126, no. 2 (2010): 515–23. http://dx.doi.org/10.1097/prs.0b013e3181df64fa.

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Chung, Kevin C., Sunitha Malay, and Melissa J. Shauver. "The Complexity of Conducting a Multicenter Clinical Trial." Plastic and Reconstructive Surgery 144, no. 6 (2019): 1095e—1103e. http://dx.doi.org/10.1097/prs.0000000000006271.

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Abbas, E. E., P. Dham, and D. Shaker. "A multicenter clinical trial in the Arab world." Transplantation Proceedings 36, no. 6 (2004): 1801–4. http://dx.doi.org/10.1016/j.transproceed.2004.07.037.

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Craig, M. T., N. S. Abramson, P. Safar, and H. Herzog. "Deferred consent in a multicenter prehospital clinical trial." Annals of Emergency Medicine 23, no. 3 (1994): 619–20. http://dx.doi.org/10.1016/s0196-0644(94)80337-4.

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Kim, Paul, Paul E. Beaulé, Yves LaFlamme, and Michael Dunbar. "Prospective Multicenter Clinical Trial of Hip Resurfacing Arthroplasty." Journal of Arthroplasty 23, no. 2 (2008): 318. http://dx.doi.org/10.1016/j.arth.2008.01.235.

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Cauch, Karen. "Early patient accrual for a multicenter clinical trial." Controlled Clinical Trials 12, no. 5 (1991): 717. http://dx.doi.org/10.1016/0197-2456(91)90330-o.

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HODISH, ISRAEL, RICHARD M. BERGENSTAL, MARY L. JOHNSON, et al. "Digitally Enhanced Insulin Therapy—A Multicenter Clinical Trial." Diabetes 67, Supplement 1 (2018): 353—OR. http://dx.doi.org/10.2337/db18-353-or.

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Dissertations / Theses on the topic "Multicenter clinical trial"

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Zahnert, Thomas, Hubert Löwenheim, Dirk Beutner, et al. "Multicenter Clinical Trial of Vibroplasty Couplers to Treat Mixed/Conductive Hearing Loss: First Results." Karger, 2016. https://tud.qucosa.de/id/qucosa%3A70599.

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Objective: To evaluate the safety and effectiveness of round window (RW), oval window (OW), CliP and Bell couplers for use with an active middle ear implant. Methods: This is a multicenter, long-term, prospective trial with consecutive enrollment, involving 6 university hospitals in Germany. Bone conduction, air conduction, implant-aided warbletone thresholds and Freiburger monosyllable word recognition scores were compared with unaided preimplantation results in 28 moderate-to-profound hearing-impaired patients after 12 months of follow-up. All patients had previously undergone failed reconst
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Stockddale, Cynthia R. "A Comparison of Community-Based Centers versus University-Based Centers in Clinical Trial Performance." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002472.

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Pereira, Joanna Tatith. "Longevidade de restaurações adesivas em dentes decíduos posteriores submetidos à remoção total ou seletiva de tecido cariado : um estudo multicêntrico." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/152662.

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A técnica da remoção seletiva de tecido cariado (RSTC) para lesões de cárie profundas em dentina de dentes decíduos e permanentes, já é consenso na literatura e é sustentada por pesquisas que demonstram excelentes resultados clínicos, radiográficos e microbiológicos. No entanto, a longevidade de restaurações adesivas realizadas após a RSTC, principalmente na dentição decídua, vem gerando algumas dúvidas e preocupações quanto ao seu desempenho, merecendo esclarecimentos. O objetivo deste estudo randomizado, controlado e multicêntrico foi comparar a taxa de sucesso de restaurações adesivas reali
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Hauke, Christina [Verfasser], Alexander [Akademischer Betreuer] Gerlach, and Susanne [Akademischer Betreuer] Zank. "The role of therapist adherence in a multicenter randomized clinical trial of patients with panic disorder and agoraphobia / Christina Hauke. Gutachter: Alexander Gerlach ; Susanne Zank." Köln : Universitäts- und Stadtbibliothek Köln, 2014. http://d-nb.info/1065801068/34.

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Xu, Shilin. "Contributions to the statistical analysis of multicenter clinical trials." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239146.

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Hardy, Rebecca Jane. "Meta-analysis techniques in medical research : a statistical perspective." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1995. http://researchonline.lshtm.ac.uk/682268/.

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Meta-analysis is now commonly used in medical research. However there are statistical issues relating to the subject that require investigation and some are considered here, from both a methodological and a practical perspective. Each of the fixed effect and the random effects models for meta-analysis are based on certain assumptions and the validity of these is investigated. A formal test of the homogeneity assumption made in the fixed effect model may be performed. Since the test has low power, simulation was used to investigate the power under various conditions. The random effects model in
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Familusi, Mary Ajibola. "Analysis of clustered competing risks with application to a multicentre clinical trial." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/23763.

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The usefulness of time-to-event (survival) analysis has made it gain a wide applicability in statistically modelling research. The methodological developments of time-to-event analysis that have been widely adopted are: (i) The Kaplan-Meier method, for estimating the survival function; (ii) The log-rank test, for comparing the equality of two or more survival distributions; (m) The Cox proportional hazards model, for examining the covariate effects on the hazard function; and (iv) The accelerated failure time model, for examining the covariate effects on the survival function. Nonetheless, in
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Niangoran, Bessekon. "Apport du monitorage statistique des données dans la gestion des essais cliniques multicentriques en Afrique." Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0436.

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La qualité des données est une préoccupation fondamentale de la recherche clinique. Pour garantir cette qualité, il faut pratiquer un monitorage continu des données. Les organismes internationaux de régulation des médicaments recommandent que ce monitorage soit ciblé, basé sur une analyse des risques. De cette recommandation a germé le concept de « monitoring statistique centralisé » (MSC) qui consiste à détecter des distributions de variables atypiques dans un centre par rapport aux autres centres. Cette thèse recense les méthodes de MSC existants, en propose de nouvelles, et compare les perf
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Rotolo, Federico. "Frailty multi-state models for the analysis of survival data from multicenter clinical trials." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3422564.

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Proportional hazards models are among the most popular regression models in survival analysis. Multi-state models generalise them in the sense of jointly considering different types of events along with their interrelations, whereas frailty models introduce random effects to account for unobserved risk factors, possibly shared by groups of subjects. The integration of frailty and multi-state methodology is interesting to control for unobserved heterogeneity in presence of complex event history structures, particularly appealing in multicenter clinical trials applications. In the present thes
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Lundberg, Elena. "Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment." Doctoral thesis, Umeå universitet, Pediatrik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-134569.

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The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. A group of 117 GHD patients who had been treated from prepuberty with a single GH dose of 33μg/kg/day for at least 1 year were randomized at onset of puberty eith
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Books on the topic "Multicenter clinical trial"

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Margie, Patlak, Nass Sharyl J, Micheel Christine, National Cancer Policy Forum (U.S.)., and Institute of Medicine (U.S.), eds. Multi-center phase III clinical trials and NCI cooperative groups: Workshop summary. National Academies Press, 2009.

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Margie, Patlak, Nass Sharyl J, Micheel Christine, National Cancer Policy Forum (U.S.)., and Institute of Medicine (U.S.), eds. Multi-center phase III clinical trials and NCI cooperative groups: Workshop summary. National Academies Press, 2009.

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Demitrack, Mark A., and Sarah H. Lisanby. Methodological issues in clinical trial design for TMS. Edited by Charles M. Epstein, Eric M. Wassermann, and Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0039.

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This article explores the emergence of transcranial magnetic stimulation (TMS) as a new therapeutic approach and the implications of this technology for the study and treatment of neuropsychiatric disorders, with a focus on major depression. Relapse, chronicity, and varying degrees of treatment resistance characterize major depression. A substantial number of patients are not effectively treated with pharmacology or medications alone. It is proposed that TMS, along with other device-based therapies emerging in psychiatry, may define a potential new treatment platform, with existing therapeutic
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Mecca, Adam P., and Rajesh R. Tampi. Effectiveness of Atypical Antipsychotic Drugs in Patients with Alzheimer’s Disease. Edited by Ish P. Bhalla, Rajesh R. Tampi, Vinod H. Srihari, and Michael E. Hochman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190625085.003.0015.

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This chapter provides a summary of the Clinical Antipsychotic Trials of Intervention Effectiveness—Alzheimer’s disease (CATIE-AD), a multicenter trial that investigated whether atypical antipsychotics are an effective treatment for psychosis, aggression, or agitation in outpatients with Alzheimer’s disease. The chapter briefly reviews the study design, as well as implications and limitations. A relevant clinical case concludes the chapter. In summary, atypical antipsychotic use for up to 36 weeks did not lead to clinical improvement based on time to discontinuation, or symptom reduction. Risk
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Jones, Byron. The Design and Analysis of Multicentre Clinical Trials. John Wiley and Sons Ltd, 2008.

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Webb, Jason A., and Arif H. Kamal. Palliative Oxygen Versus Room Air for Refractory Dyspnea (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0017.

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Palliative oxygen therapy is used for treating dyspnea in patients with cancer and advanced cardiopulmonary diseases, however, small trials have suggested that circulating air may be just as effective. This international, multicenter, randomized controlled trial compared oxygen versus room air delivered by a nasal cannula for relief of dyspnea for patients with any life-limiting illness. Patients were adults >18 years of age, with PaO2 > 7.3kPa, on optimized therapies for their illness, and an expected survival of >1 month. The study demonstrated no clinically significant symptomatic
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Patlak, Margie, Institute of Medicine, National Cancer Policy Forum, Christine Micheel, and Sharyl Nass. Multi-Center Phase III Clinical Trials and NCI Cooperative Groups: Workshop Summary. National Academies Press, 2009.

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Patlak, Margie, Institute of Medicine, National Cancer Policy Forum, Christine Micheel, and Sharyl Nass. Multi-Center Phase III Clinical Trials and NCI Cooperative Groups: Workshop Summary. National Academies Press, 2009.

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Patlak, Margie, Institute of Medicine, National Cancer Policy Forum, Christine Micheel, and Sharyl Nass. Multi-Center Phase III Clinical Trials and NCI Cooperative Groups: Workshop Summary. National Academies Press, 2009.

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Book chapters on the topic "Multicenter clinical trial"

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Svantesson, Eleonor, Eric Hamrin Senorski, Alicia Oostdyk, Yuichi Hoshino, Kristian Samuelsson, and Volker Musahl. "Multicenter Study: How to Pull It Off? The PIVOT Trial." In Basic Methods Handbook for Clinical Orthopaedic Research. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-58254-1_43.

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Hébert, P. C. "Transfusion Requirements in Critical Care: A Multicenter Controlled Clinical Trial." In Yearbook of Intensive Care and Emergency Medicine. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72038-3_18.

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Rutsch, Wolfgang, Patrick W. Serruys, Guy R. Heyndrickx, et al. "CARPORT — Coronary artery restenosis prevention on repeated thromboxane antagonism. A multicenter randomized clinical trial." In Developments in Cardiovascular Medicine. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1854-5_20.

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Kichikawa, Kimihiko, Shoji Sakaguchi, Wataru Higashiura, and Hideo Uchida. "Multicenter Clinical trial of Zenith AAA Endovascular Graft for Abdominal Aortic Aneurysm in Japan." In Advances in Understanding Aortic Diseases. Springer Japan, 2009. http://dx.doi.org/10.1007/978-4-431-99237-0_22.

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Koh, Jason L., Shital Parikh, and Beth Shubin Stein. "Conducting a Multicenter Trial: Learning from the JUPITER (Justifying Patellar Instability Treatment by Early Results) Experience." In Basic Methods Handbook for Clinical Orthopaedic Research. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-58254-1_44.

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Kasuya, H. "Clinical Trial of Nicardipine Prolonged-Release Implants for Preventing Cerebral Vasospasm: Multicenter Cooperative Study in Tokyo." In Early Brain Injury or Cerebral Vasospasm. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0356-2_30.

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Ginsberg, Myron D. "High-Dose Albumin for Neuroprotection in Acute Ischemic Stroke: From Basic Investigations to Multicenter Clinical Trial." In Translational Stroke Research. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-9530-8_34.

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Friedman, Lawrence M., Curt D. Furberg, and David L. DeMets. "Multicenter Trials." In Fundamentals of Clinical Trials. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1586-3_20.

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Friedman, Lawrence M., Curt D. Furberg, and David L. DeMets. "Multicenter Trials." In Fundamentals of Clinical Trials. Springer New York, 1998. http://dx.doi.org/10.1007/978-1-4757-2915-3_19.

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Friedman, Lawrence M., Curt D. Furberg, David L. DeMets, David M. Reboussin, and Christopher B. Granger. "Multicenter Trials." In Fundamentals of Clinical Trials. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-18539-2_21.

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Conference papers on the topic "Multicenter clinical trial"

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Ingeholm, Mary-Lou, Betty A. Levine, Florian Eichler, Huacheng Tu, Gerardo Jimenez-Sanchez, and Hugo Moser. "Multicenter clinical trial using next-generation Internet technology." In Medical Imaging 2001, edited by Eliot L. Siegel and H. K. Huang. SPIE, 2001. http://dx.doi.org/10.1117/12.435470.

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Zaccaria, Gian Maria, Samanta Rosati, Cristina Castagneri, et al. "Data quality improvement of a multicenter clinical trial dataset." In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2017. http://dx.doi.org/10.1109/embc.2017.8037043.

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Borges, Guilherme Ferreira, Hélio Rubens de Carvalho Nunes, Gustavo José Luvizutto, Taís Regina da Silva, and Rodrigo Bazan. "Lessons of a multicenter noninvasive brain stimulation trial in patients with unilateral spatial neglect after stroke: barriers to trial participation from a developing country." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.482.

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Background: There is a high demand for stroke rehabilitation in the Brazilian public health system, however most studies that addressed rehabilitation for unilateral spatial neglect (USN) after stroke have been performed in highincome countries. Objectives: Analyze the USN patient recruitment in a multicenter non-invasive brain stimulation clinical trial performed in Brazil. Design and setting: Observation study of reasons for exclusion of patients in a multicenter, randomized, double-blinded clinical trial performed at Botucatu Medical School. Methods: We evaluated reasons for exclusion of pa
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Tavanapong, Wallapak, JungHwan Oh, Gavin Kijkul, Jacob Pratt, Johnny Wong, and Piet deGroen. "Real-Time Feedback for Colonoscopy in a Multicenter Clinical Trial." In 2020 IEEE 33rd International Symposium on Computer-Based Medical Systems (CBMS). IEEE, 2020. http://dx.doi.org/10.1109/cbms49503.2020.00010.

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Winslow, C. J., D. P. Edelson, M. M. Churpek, et al. "The Impact of an Early Warning Score on Hospital Mortality: A Multicenter Clinical Intervention Trial." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2462.

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Galperin-Aizenberg, Maya, Hyun J. G. Kim, Peiyun Lu, et al. "Reproducibility Of Lung Volume Measurements Using Computed Tomography From Repeated Scans In A Multicenter Clinical Trial." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4607.

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Santos, Gabriel Cerqueira, Caio de Almeida Lellis, Bruno Coelho Duarte Oliveira, Letícia Romeira Belchior, Caíque Seabra Garcia de Menezes Figueiredo, and Ledismar José da Silva. "Botulinum toxin type A in the treatment of Myofascial Pain Syndrome: A Systematic Review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.263.

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Introduction: Myofascial pain syndrome (MPS) is a regional painful condition characterized by the presence of trigger points in the affected muscles, and botulinum toxin type A (BoNT-A) is a possible therapeutic option. Objectives: To evaluate the safety and efficacy of botulinum toxin in the management of MSD. Design and setting: A systematic review conducted at the Pontifical Catholic University of Goiás. Methodology: A systematic review was conducted in the PubMed, IBECS and VHL databases: “(Myofascial Pain Syndromes OR Myofascial Trigger Point Pain) AND Botulinum toxin”. Randomized studies
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Karimzadeh, A., SA Raeissadat, S. Erfani fam, and L. Sedighipour. "SAT0604 Autologous blood and corticosteroid local injection in treatment of plantar fasciitis (randomized, controlled multicenter clinical trial)." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.1771.

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Meyer, JS, S. Seefeldt, J. Lange, M. Heiss, D. Seidel, and R. Lefering. "BIOLAP: Biological versus synthetic mesh in laparoscopic hernia repair-a randomized multicenter, prospective, self-controlled clinical trial." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605325.

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Maas, M., H. Neumann, H. Shirin, et al. "A novel computer-aided polyp detection system in daily clinical care: an international multicenter, randomized, tandem trial." In ESGE Days 2023. Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/s-0043-1765015.

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Reports on the topic "Multicenter clinical trial"

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Robles, Marcelo, Claudio Dachevsky, and Héctor Llovera. Prospective study: evaluation of the efficacy and longevity of cross-linked hyaluronic acid in nasolabial folds filling. Editorial Lugones, 2023. http://dx.doi.org/10.47196/0574.

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Introduction: the choice of minimally invasive methods positions hyaluronic acid fillers as a leading facial rejuvenation technique. Injectable hyaluronic acid fillers have been widely used in the clinical treatment of facial wrinkles. However, additional information and clinical evidence on the longevity of hyaluronic acid filler after injection is limited. Objectives: to demonstrate the efficacy, safety and longevity of cross-linked HA (AHR) 30 mg/ml (Estrianon Hyaluronic Implant 30® Allanmar International Company S.R.L., Argentina) for filling nasolabial folds (NLF). Design: multicenter, pr
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Viskochil, David, Brigitte Widemann, Jan Friedman, Rosalie Ferner, and Arie Perry. Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: A Multicenter Project With 3 Clinical Trials. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada460467.

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You might also be interested in the extended bibliographies on the topic 'Multicenter clinical trial' for particular source types:
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