Academic literature on the topic 'Multicomponent couplings'

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Journal articles on the topic "Multicomponent couplings"

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Le Gall, Erwan, Jérôme Paul, Marc Presset, Eric Léonel, and Pascal Retailleau. "Insights into the Cobalt-Catalyzed Three-Component Coupling of Mixed Aromatic Organozinc Species, Carbonyl Compounds or Imines and Michael Acceptors: Synthetic and Mechanistic Aspects." Synthesis 50, no. 02 (2017): 254–66. http://dx.doi.org/10.1055/s-0036-1590957.

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The first examples of cobalt-catalyzed multicomponent couplings of mixed aromatic arylzinc reagents with Michael acceptors and carbonyl compounds or imines is described. The reaction system employs a cobalt(II)-2,2′-bipyridine or a cobalt(II)-1,10-phenanthroline complex as a catalyst for both organozinc generation and subsequent multicomponent assembly by formal Michael addition/aldol coupling or Mannich reaction. This study brings new insights into the synthetic scope and mechanism of the reaction.
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Yang, Hongwei, Huanhe Dong, Baoshu Yin, and Zhenyu Liu. "Nonlinear Bi-Integrable Couplings of Multicomponent Guo Hierarchy with Self-Consistent Sources." Advances in Mathematical Physics 2012 (2012): 1–14. http://dx.doi.org/10.1155/2012/272904.

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Based on a well-known Lie algebra, the multicomponent Guo hierarchy with self-consistent sources is proposed. With the help of a set of non-semisimple Lie algebra, the nonlinear bi-integrable couplings of the multicomponent Guo hierarchy with self-consistent sources are obtained. It enriches the content of the integrable couplings of hierarchies with self-consistent sources. Finally, the Hamiltonian structures are worked out by employing the variational identity.
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Lu, Fu-Dong, Gui-Feng He, Liang-Qiu Lu, and Wen-Jing Xiao. "Metallaphotoredox catalysis for multicomponent coupling reactions." Green Chemistry 23, no. 15 (2021): 5379–93. http://dx.doi.org/10.1039/d1gc00993a.

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The key advances in the field of metallaphotoredox-catalyzed multicomponent couplings in recent years are highlighted in this review. To better meet the needs of modern chemistry, further research outlooks were also proposed.
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Fereyduni, Ehsan, Jacob N. Sanders, Gabriel Gonzalez, K. N. Houk, and Alexander J. Grenning. "Transient [3,3] Cope rearrangement of 3,3-dicyano-1,5-dienes: computational analysis and 2-step synthesis of arylcycloheptanes." Chemical Science 9, no. 46 (2018): 8760–64. http://dx.doi.org/10.1039/c8sc03057j.

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Odell, Luke, Mats Larhed, and Linda Åkerbladh. "Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions." Synlett 30, no. 02 (2018): 141–55. http://dx.doi.org/10.1055/s-0037-1610294.

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This account summarizes Pd(0)-catalyzed Mo(CO)6-mediated gas-free carbonylative reactions published in the period October 2011 to May 2018. Presented reactions include inter- and intramolecular carbonylations, carbonylative cross-couplings, and carbonylative multicomponent reactions using Mo(CO)6 as a solid source of CO. The presented methodologies were developed mainly for small-scale applications, avoiding the problematic use of gaseous CO in a standard laboratory. In most cases, the reported Mo(CO)6-mediated carbonylations were conducted in sealed vials or by using two-chamber solutions.1 I
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Xia, Tiecheng, and Engui Fan. "The multicomponent generalized Kaup–Newell hierarchy and its multicomponent integrable couplings system with two arbitrary functions." Journal of Mathematical Physics 46, no. 4 (2005): 043510. http://dx.doi.org/10.1063/1.1866220.

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Liu, Lei, Maria Camila Aguilera, Wes Lee, Cassandra R. Youshaw, Michael L. Neidig, and Osvaldo Gutierrez. "General method for iron-catalyzed multicomponent radical cascades–cross-couplings." Science 374, no. 6566 (2021): 432–39. http://dx.doi.org/10.1126/science.abj6005.

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Iron links a trio Iron holds particular appeal as a catalytic metal—it is safe and abundant, as well as a mainstay of enzymatic reactivity. Nonetheless, in synthetic construction of carbon-carbon bonds, modern chemists have largely had to rely on rarer metals such as palladium. Liu et al . now report that coordination of iron by a bulky chelating phosphine ligand enables efficient mutual coupling of three different reactants—an alkyl halide, an aryl Grignard, and an olefin—to form two carbon-carbon bonds (see the Perspective by Lefèvre). A combination of Mössbauer spectroscopy, crystallography
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Odom, Aaron L., and Tanner J. McDaniel. "Titanium-Catalyzed Multicomponent Couplings: Efficient One-Pot Syntheses of Nitrogen Heterocycles." Accounts of Chemical Research 48, no. 11 (2015): 2822–33. http://dx.doi.org/10.1021/acs.accounts.5b00280.

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El Kaim, Laurent, Marie Gizolme, Laurence Grimaud, and Julie Oble. "Direct Access to Heterocyclic Scaffolds by New Multicomponent Ugi−Smiles Couplings." Organic Letters 8, no. 18 (2006): 4019–21. http://dx.doi.org/10.1021/ol061605o.

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Smith, Amos B., and Armen M. Boldi. "Multicomponent Linchpin Couplings of Silyl Dithianes via Solvent-Controlled Brook Rearrangement." Journal of the American Chemical Society 119, no. 29 (1997): 6925–26. http://dx.doi.org/10.1021/ja970371o.

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Dissertations / Theses on the topic "Multicomponent couplings"

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Lear, Jeremy M. "Polarity-Reversal Cascades for the Coupling of Radicals with Unsaturated Systems." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1562958629394222.

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Pablo, Hélène. "Diffusion chimique dans les verres borosilicates d'intérêt nucléaire." Thesis, Paris, Muséum national d'histoire naturelle, 2017. http://www.theses.fr/2017MNHN0014/document.

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La diffusion chimique est un phénomène clé dans l’élaboration des verres d’intérêt nucléaire. A haute température, dans le liquide, elle permet l’homogénéisation des flux de matière (précurseurs vitreux et déchets) et conduit à la formation d’un verre homogène après refroidissement. A contrario, dans le liquide surfondu, elle peut être à l’origine de processus de séparation de phase ou de cristallisation qui doivent être contrôlés pour le bon fonctionnement du procédé. Dans cette thèse, l’influence de la diffusion chimique sur les processus de cristallisation et d’homogénéisation du liquide es
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Carmona, Rafaela Costa. "Estratégias assimétricas em reações de acoplamento A3." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-23042013-082023/.

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A presente dissertação de mestrado descreve estudos sobre as reações multicomponentes A3 na versão assimétrica. Diversas metodologias foram empregadas visando a obtenção de propargilaminas opticamente ativas, que são blocos sintéticos versáteis na preparação de compostos bioativos. O trabalho foi dividido em duas partes. Na primeira parte, estudou-se a utilização de aminas opticamente puras como materiais de partida para a reação tricomponente A3. Neste caso, foi utilizada a 2-metilpropan-2-sulfinamida como amina principal, no entanto, o produto de acoplamento não foi obtido, mesmo em diversas
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Schevciw, Evelyn Pucci. "Reações de acoplamento-A3 visando a síntese da desoxicastanospermina e swainsonina." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-20072015-135552/.

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Esta dissertação de mestrado descreve os resultados obtidos acerca da aplicação de reações de acoplamento entre aldeídos, aminas e alquinos (A3) visando a síntese de alcalóides indolizidínicos de ocorrência natural, como a desoxicastanospermina e a swainsonina. A reação de acoplamento-A3 é uma poderosa ferramenta de construção de ligação carbono-carbono e carbono-heteroátomo, permitindo a preparação de propargilaminas que podem ser exploradas como intermediários de grande potencial sintético. A proposta está baseada na reação de acoplamento de um reagente organometálico, gerado in situ a parti
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Cho, Hee Yeon. "Catalytic Borylative Multicomponent Coupling Reactions and Novel Chemistry of Polycyclic Aromatic Hydrocarbons." Thesis, Boston College, 2013. http://hdl.handle.net/2345/3398.

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Thesis advisor: Lawrence T. Scott<br>Thesis advisor: James P. Morken<br>Expeditious establishment of molecular complexity in a stereoselective manner is a prominent goal in organic synthesis. In this regard, multicomponent coupling reactions have received substantial attention due to their ability to access complex molecules from simple starting materials in a single step. Chapter 1 is a comprehensive review on catalytic bismetallative multicomponent reactions. The scope of this process in terms of both bismetallic reagents and the pi components are broad enough to be generally applied to more
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Maddirala, Amarendar Reddy. "Applications of Ugi Four Component Cascade Coupling Reactions for the Synthesis of Bioactive Diverse Heterocyclic Molecules and Natural Products." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1461775415.

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Bell, Christan Elizabeth. "Synthesis and Reactivity of New Organoboron Reagents and Development of New Methodologies for the Generation of Novel Drug-Like Scaffolds." Diss., The University of Arizona, 2012. http://hdl.handle.net/10150/265557.

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This research focused on the synthesis of novel ogranoboron reagents in efforts to perform a variety of synthetic transformations, and additionally, the development of new methodologies to generate drug-like scaffolds. Initially, three novel tripod ligands were synthesized, and two were effectively chelated to boron to provide the desired organoborates. Such organoborates were employed in nucleophilic additions where they were found to be ineffective, whereas some activity was observed in Suzuki-Miyaura cross-coupling reactions. An additional project on organoboron compounds was conducted and
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Older, Christina M. "Allyl/alkyne coupling reactions mediated by ruthenium(II), carbon-carbon bond activations and multicomponent cycloadditions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0014/NQ60009.pdf.

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Ben, Abdessalem Abdelbari. "Réactions multicomposant à base des isonitriles." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLY024/document.

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Les réactions multicomposant à base d'isonitrile (I-MCR) combinées à des transformations de post-condensation constituent des outils de synthèse extrêmement puissants pour la préparation de structures moléculaires complexes et diverses avec de nouvelles propriétés pharmacologiques.Dans un premier temps, nous nous sommes intéressés à l'extension du couplage de Ugi-Smiles aux dérivés de purines, en utilisant la 6-mercaptopurine comme partenaire de couplage. Cette méthodologie permet un accès direct et rapide aux dérivés d'adénine avec des rendements modérés à bons à partir de précurseurs simples
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Le, Meur Mikaël. "Identification de nouveaux inhibiteurs de l’agrégation de la protéine Tau." Thesis, Orléans, 2014. http://www.theses.fr/2014ORLE2046.

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Parmi la vingtaine de pathologies neurodégénératives recensées à ce jour, il a été retrouvé des caractéristiques communes telles que des lésions neuronales. Dans le cas de la Maladie d’Alzheimer, une dégénérescence neurofibrillaire a notamment été mise en évidence, ce qui se traduit par l’agrégation de protéines Tau anormalement modifiées. Bien que les mécanismes moléculaires impliqués demeurent encore mal compris, nous nous sommes intéressés, au cours de cette thèse, à la synthèse puis à l’évaluation biologique de nouveaux inhibiteurs de l’agrégation de la protéine TAU impliquée dans la Malad
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Book chapters on the topic "Multicomponent couplings"

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Kaïm, Laurent El, and Laurence Grimaud. "Ugi-Smiles and Passerini-Smiles Couplings." In Multicomponent Reactions in Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527678174.ch04.

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Tojino, Mami, and Ilhyong Ryu. "Free-Radical-Mediated Multicomponent Coupling Reactions." In Multicomponent Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527605118.ch6.

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Hughes, G. O., and R. I. Nokes. "‘Wave-Convection Coupling' in Multicomponent Convection: An Experimental Study." In Geophysical Monograph Series. American Geophysical Union, 2013. http://dx.doi.org/10.1029/gm094p0049.

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Patel, Krishnakant, and Peter R. Andreana. "Recent Advances in the Stereochemical Outcome of Multicomponent Reactions Involving Convertible Isocyanides." In Coupling and Decoupling of Diverse Molecular Units in Glycosciences. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-65587-1_3.

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Moni, Lisa, Andrea Basso, and Renata Riva. "Combination of Cross-Coupling and Metal Carbene Transformations for the Development of New Multicomponent Reactions." In Carbon-related Materials in Recognition of Nobel Lectures by Prof. Akira Suzuki in ICCE. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-61651-3_12.

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Suginome, M., and Y. Ito. "The Passerini Reaction and Ugi Reaction: Multicomponent Couplings by an α-Addition Reaction." In Three Carbon-Heteroatom Bonds: Nitriles, Isocyanides, and Derivatives. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-019-00343.

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Nakata, M. "Multicomponent Coupling of 2-Silyl-1,3-dithianes." In Acetals: O/N, S/S, S/N, and N/N and Higher Heteroatom Analogues. Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-030-00312.

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Li, W.-R. "Multicomponent Coupling of Aldehydes, Amides, and Dienophiles." In Three Carbon-Heteroatom Bonds: Esters and Lactones; Peroxy Acids and R(CO)OX Compounds; R(CO)X, X=S, Se, Te. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-021-00184.

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André-Joyaux, E., L. Gnägi, C. Melendez, V. Soulard, and P. Renaud. "1.11 Generation of Radicals from Organoboranes." In Free Radicals: Fundamentals and Applications in Organic Synthesis 1. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/sos-sd-234-00224.

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AbstractRadicals can be generated by the cleavage of the C—B bond of alkylboranes or boronic acid derivatives. The fragmentation process may result from a nucleohomolytic substitution process or from a redox process. The nucleohomolytic substitution is ideal for the generation of alkyl radicals and is usually part of a chain-reaction process. Redox processes (mainly oxidative reactions) have been used to generate both alkyl and aryl radicals. The use of stoichiometric oxidizing agents can be avoided by employing photoredox catalysis. A broad range of synthetic applications such as radical cascade processes, multicomponent reactions, and cross-coupling reactions in the presence of suitable metal catalysts are now possible. In their diversity, organoboron compounds represent one of the most general sources of radicals. The merging of radical chemistry with the classical chemistry of organoboron derivatives opens tremendous opportunities for applications in organic synthesis.
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Taber, Douglass F. "The Boger Synthesis of (+)-Complestatin." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0102.

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(+)-Complestatin 3 shows promising activity against HIV infectivity. Dale L. Boger of Scripps/La Jolla described (J. Am. Chem. Soc. 2010, 132, 7776) an elegant multicomponent assembly of 3, the key step of which was the atropisomer-selective intramolecular Larock cyclization of 1 to 2. The preparation of 1 began with the protected phenethylamine 5, prepared by Sharpless asymmetric aminohydroxylation of the styrene 4. Conversion of 5 to the areneboronic acid followed by coupling with 6 delivered 7. Acylation led to 8, with the stage set for nitro-assisted addition-elimination, to form the first bis-aryl ether of 3. The product was a mixture of atropisomers, subsequently symmetrized to 9 by removal of the nitro group. Acylation of 9 led to 1. The role of the silyl group on the alkyne of 1 was to direct the regioselectivity of the intramolecular Larock indole synthesis. Again, two atropisomers were possible from the cyclization. Earlier model studies had suggested some preference for one over the other. As it turned out, in this case the desired atropisomer was the only one observed. It is particularly striking that the coupling was efficient even in the presence of the readily reduced and unprotected chlorophenols. The modular nature of this route to (+)-complestatin 3 will make it possible to prepare a variety of analogues. As long as only the substituents on the periphery are changed, the atropisomer selectivity in the Larock cyclization should be maintained.
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Conference papers on the topic "Multicomponent couplings"

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Bugar, Ignac, Jozef Chovan, Martin Koys, et al. "Nonlinear and Coupling Performance of Multicomponent Glass Double Core Photonic Crystal Fiber." In 2008 10th Anniversary International Conference on Transparent Optical Networks (ICTON 2008). IEEE, 2008. http://dx.doi.org/10.1109/icton.2008.4598705.

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Liu, H., L. S. Cheng, and P. Jia. "Coupling Heat and Mass Transfer at Interface for ES-SAGD with Multicomponent Solvent Injection." In 79th EAGE Conference and Exhibition 2017. EAGE Publications BV, 2017. http://dx.doi.org/10.3997/2214-4609.201701345.

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Narh, K. A., and M. Xanthos. "Prototype Design and Process Optimization Procedure for Products From Glass-Fiber Reinforced Polymer Blends." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0626.

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Abstract In order to minimize the effects of compositional variation in multiphase, multicomponent polymer mixtures equivalent to those found in commingled waste streams, such as those obtained from reclamation/recycling operations of post-consumer containers, several plastic composites containing varying amounts of glass fiber and different compatibilizers/coupling agents are studied. The glass-fiber reinforced composites, based on characteristic compositions simulating post-consumer “curbside tailings”, have been designed and molded into thin-section parts. Structural, and flow analyses were
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Uchibori, Akihiro, Shin Kikuchi, Akikazu Kurihara, Hirotsugu Hamada, and Hiroyuki Ohshima. "Multiphysics Analysis System for Tube Failure Accident in Steam Generator of Sodium-Cooled Fast Reactor." In 2013 21st International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icone21-16692.

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Multiphysics analysis system was newly developed to evaluate possibility of failure propagation occurrence under heat transfer tube failure accident in a steam generator of sodium-cooled fast reactors. The analysis system consists of the computer codes, SERAPHIM, TACT, RELAP5, which are based on the mechanistic numerical models. The SERAPHIM code calculates the multicomponent multiphase flow involving sodium-water chemical reaction. In this study, numerical models for the chemical reaction about production of a sodium monoxide and its transport process were constructed to enable evaluation of
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Guo, Liancheng, Koji Morita, Hirotaka Tagami, and Yoshiharu Tobita. "Numerical Simulation of Self-Leveling Behavior in Debris Bed by a Hybrid Method." In 2013 21st International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icone21-15483.

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The postulated core disruptive accidents (CDAs) are regarded as particular difficulties in the safety analysis of liquid-metal fast reactors (LMFRs). In the CDAs, the self-leveling behavior of debris bed is a crucial issue to the relocation of molten core and heat-removal capability of the debris bed. The fast reactor safety analysis code, SIMMER-III, which is a 2D, multi-velocity-field, multiphase, multicomponent, Eulerian, fluid dynamics code coupled with a fuel-pin model and a space- and energy-dependent neutron kinetics model, was successfully applied to a series of CDA assessments. Howeve
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Zhou, Wenning, Yuying Yan, and Xiaoping Luo. "Numerical Investigation on Interfacial Phenomena of Ferrofluid by Lattice Boltzmann Method." In ASME 2013 11th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icnmm2013-73173.

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Ferrofluid, also known as magnetic fluid, is a new-type fluid whose property and morphology can be controlled by the external magnetic field. It mainly consists of carrier fluid and suspended magnetic particles (diameter usually 10 nanometers or less). Ferrofluids behave as a smart or functional fluid and has been finding more and more applications in a variety of fields such as electronic packing, mechanical engineering, aerospace, bioengineering, and thermal engineering. It has therefore recently attracted many researchers’ interest. Due to the nanosize particles and complex interactions bet
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Alonso, Dominique, Ghislain Genin, David Heller, Brice Chabrier, and Michel Molie`re. "Evaporation of Volatile Liquid Pools Under Forced Convection: Experimental Approach for Multi-Component Liquids and Validation of a Vaporization Model." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-45560.

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The evaporation of pools of volatile liquids under dynamic conditions is gaining interest as an engineering subject. Indeed there is an increasing need to optimize the control of thermal or chemical processes and to cope with more and more stringent Environmental, Health and Safety (EHS) regulations applicable to the handling of hazardous liquids, especially those relating to stationary gas turbine installations. A specific issue, tied with flammable substances, comes from the fact that the transition from a flame to an explosion is not sufficiently well controlled due to the difficulty in mod
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