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Journal articles on the topic 'Multidrug-Resistant/microbiology'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Sheehan, Frances, Meru Sheel, Karina Kennedy, and Kathryn Daveson. "SG-APSIC1136: Multidrug-resistant organisms: Elevating issues identified by antimicrobial stewardship to improve infection control responses." Antimicrobial Stewardship & Healthcare Epidemiology 3, S1 (2023): s26. http://dx.doi.org/10.1017/ash.2023.77.

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Objectives: Resistance to third-generation cephalosporins in Escherichia coli bacteremia is on the rise in Australia. Currently, laboratory definitions of multidrug-resistant organisms determine infection control responses. The incidence of particular extended-spectrum β-lactamase (ESBL) E. coli phenotype, with nonsusceptibility to both ciprofloxacin and trimethoprim-sulfamethoxazole, is increasing in the Australian Capital Territory, Australia. The increase was noted primarily through antimicrobial stewardship clinical care rather than standard infection control or microbiology processes. Cli

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Bhatta, Sabita, Manoj Pradhan, and Raina Chaudhary. "Multidrug-resistant among Non-Fermenting Gram-negative Bacteria Isolated in the Department of Microbiology of a Tertiary Care Centre." Journal of Nepal Medical Association 61, no. 267 (2023): 868–70. http://dx.doi.org/10.31729/jnma.8330.

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Introduction: Infection caused by Non-fermenting Gram-negative bacteria (NFGNB) like Pseudomonas aeruginosa and Acinetobacter baumannii leads to life-threatening conditions. These bacteria are often multidrug-resistant which leads to limited therapeutic options leading to treatment failure. Little information is available regarding the prevalence and resistance pattern of such bacteria in our country. The aim of the study was to find out the prevalence of multidrug-resistant among non-fermenting Gram-negative bacteria isolated in the Department of Microbiology of a tertiary care centre. Method

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Morita, Yuji, and Kunihiko Nishino. "Frontier of Pharmaceutical Microbiology: To Combat Multidrug-resistant Bacterial Pathogens." YAKUGAKU ZASSHI 137, no. 4 (2017): 371–72. http://dx.doi.org/10.1248/yakushi.16-00235-f.

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4

Basak, Silpi, Priyanka Singh, and Monali Rajurkar. "Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study." Journal of Pathogens 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/4065603.

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Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a tertiary care hospital.Material and Methods. The clinical samples were cultured and bacterial strains were identified in the department of microbiology. The antibiotic susceptibility profile of different bacterial isolates was studied to detect MDR, XDR, and PDR bacteria.Results. The antibiotic suscept

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Sara Kouara, Wiame Ghammad, Selma Berrada, Mustapha Mahmoud, and Mustapha Mahmoud. "Epidemiological profile of multi-drug resistant bacteria in pediatric intensive care unit." International Journal of Life Science Research Archive 4, no. 2 (2023): 057–62. http://dx.doi.org/10.53771/ijlsra.2023.4.2.0058.

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Multidrug-resistant bacteria are currently a major health problem in our hospitals and a current medical issue due to the morbidity and mortality it causes, especially in intensive care units. The objective of this study is to describe the epidemiological profile, frequency, and resistance status of multidrug-resistant bacteria in pediatric and neonatal intensive care units. We conducted a retrospective study at the microbiology laboratory of the Hassan II University Hospital in Fez in 2022, where we collected bacterial samples from these two units that identified a multidrug-resistant bacteri

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Yadav, Ajay, Basudha Khanal, Amit Kumar Patel, and Alina Karna. "Invitro Activity of Tigecycline against Multidrug-Resistant Enterobacteriaceae from Blood Stream Infection at a Tertiary Care Hospital of Nepal." Nepal Journal of Health Sciences 2, no. 2 (2022): 27–33. http://dx.doi.org/10.3126/njhs.v2i2.56788.

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Introduction: Any bacterial isolates showing resistant to three or more than three different types of antimicrobial groups are termed as multidrug resistant. Such superbugs have shown significant challenge not only to microbiologist but also to clinicians. Multidrug resistant like extended-spectrum and metallo-beta lactamase are being encountered as the causative agents of blood stream infection. Accurate diagnosis of blood stream infection, timely isolation and identification of the causative agents and determination of their antimicrobial susceptibility are crucial, as effective management d

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Banawas, Saeed S. "Emergence of Multidrug-resistant Acinetobacter baumannii: A Growing Health Concern in the Qassim Region, Kingdom of Saudi Arabia." Advances in Human Biology 14, no. 3 (2024): 235–41. http://dx.doi.org/10.4103/aihb.aihb_39_24.

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Introduction: Acinetobacter baumannii is a multidrug-resistant bacterium commonly associated with hospital-acquired infections. The rapid spread of A. baumannii has raised concerns, as it has been linked to the emergence of clones in healthcare facilities worldwide. The challenges of treating and controlling infections caused by this bacterium in hospital settings are exacerbated by its resistance profile. The proliferation of clones worldwide highlights the need for careful infection control procedures and new tactics to fight illnesses caused by drug-resistant A. baumannii strains. Materials

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Raisa, Mahnaz Tabassum, Abu Naser Ibne Sattar, Sanjida Khondakar Setu, and Quazi Mehranuddin Ahmed. "Detection of blaCTX-M Gene Variants among Multidrug Resistant Klebsiella Species and Escherichia coli from Clinical Isolates at a Tertiary Care Hospital in Bangladesh." Bangladesh Journal of Medical Microbiology 19, no. 1 (2025): 46–53. https://doi.org/10.3329/bjmm.v19i1.80346.

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Background: There are more than 10 families of genes associated with ESBL, among them the highest number of variants corresponds to the CTX-M family. Gene encoding CTX-M (blaCTX-M) has several allelic variants, which has different geographical distributions. Objective: The aim of the study was to detect distribution of blaCTX-M gene among multidrug resistant Escherichia coli and Klebsiella species along with it’s subtypes among different clinical samples. Methodology: Isolation and identification of Escherichia coli and Klebsiella species was done from clinical isolates sent for culture and se

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K., Archana Rao, Sangeetha S., and Lakshminarayana SA. "NDM-1 gene detection from Metallobeta lactamase (MBL) producing Pseudomonas aeruginosa: A pilot study from a teritiary care centre." International journal of Microbiology and Mycology (IJMM) 10, no. 1 (2019): 1–7. https://doi.org/10.5281/zenodo.8424527.

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Multidrug resistant bacteria always remain a great challenge. The latest threat being New Delhi Metallobetalactamase-1 (NDM-1) a superbug has brought notoriety to Indian Health care. NDM-1 refers to the transmissible genetic element encoding multiple resistant genes, first isolated from a strain of <em>Klebsiella</em> spp. in New Delhi, India, which has the ability to hydrolyse beta lactams and carbapenams. Detection of NDM-1 gene in multidrug resistant Pseudomonas isolates from various clinical samples. 200 Pseudomonas species were isolated in Microbiology laboratory during one year

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SAHLI, Z. T., A. R. BIZRI, and G. S. ABU-SITTAH. "Microbiology and risk factors associated with war-related wound infections in the Middle East." Epidemiology and Infection 144, no. 13 (2016): 2848–57. http://dx.doi.org/10.1017/s0950268816000431.

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SUMMARYThe Middle East region is plagued with repeated armed conflicts that affect both civilians and soldiers. Injuries sustained during war are common and frequently associated with multiple life-threatening complications. Wound infections are major consequences of these war injuries. The microbiology of war-related wound infections is variable with predominance of Gram-negative bacteria in later stages. The emergence of antimicrobial resistance among isolates affecting war-related wound injuries is a serious problem with major regional and global implications. Factors responsible for the in

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Chaudhary, Raina, Sabita Bhatta, Chiranjibi Pant, Naveen Phuyal, and Lochana Shrestha. "Multidrug Resistance Gram-negative Bacteria in Intensive Care Unit of Tertiary Care Hospital: A Descriptive Cross-sectional Study." Journal of Nepal Medical Association 62, no. 277 (2024): 582–86. http://dx.doi.org/10.31729/jnma.8747.

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Introduction: Antimicrobial resistance is global health problem, amongst major causes for mortality. It is one of the hinderance for achievement of Sustainable Goal 3 (Good health and well-being) of WHO. Multidrug resistant gram negative bacteria are major threat to humanity especially patients admitted in intensive care unit. This is associated with to treatment failure and mortality of the patients in intensive care unit. Therefore, this study was conducted to find out the prevalence of Multidrug resistant gram negative bacteria in intensive care unit of tertiary care center. Methods: A desc

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Chaudhary, Raina, Manoj Pradhan, Sabita Bhatta, Sabnum Shrestha, Nabaraj Adhikari, and Yengkokpam Ibotomba Singh. "Multidrug Resistant Escherichia coli among Urinary Samples of Patients with Urinary Tract Infection in the Microbiology Department of a Tertiary Care Center: A Descriptive Cross-Sectional Study." Journal of Nepal Medical Association 61, no. 261 (2023): 437–41. http://dx.doi.org/10.31729/jnma.8160.

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Introduction: Urinary Tract Infection one of the most common and manageable infections still holds its position as a major public health issue worldwide due to an increase in the number of multidrug resistant bacteria. This study aims to find out the prevalence of multidrug resistant Escherichia coli among urinary samples of patients with urinary tract infections in the microbiology Department of a tertiary care center. Methods: A descriptive cross-sectional study was carried out at a tertiary care centre from 8 August 2018 to 9 January 2019. Ethical approval was received from the Institutiona

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Mizusawa, Masako, Heather Miller, Rachel Green, et al. "Can Multidrug-Resistant Candida auris Be Reliably Identified in Clinical Microbiology Laboratories?" Journal of Clinical Microbiology 55, no. 2 (2016): 638–40. http://dx.doi.org/10.1128/jcm.02202-16.

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Peterson, Lance. "New Technology for Detecting Multidrug-Resistant Pathogens in the Clinical Microbiology Laboratory." Emerging Infectious Diseases 7, no. 2 (2001): 306–11. http://dx.doi.org/10.3201/eid0702.010233.

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Shugart, Alicia, Maroya Spalding Walters, Lindsey M. Weiner, David Lonsway, and Alexander J. Kallen. "Hospital microbiology laboratory practices for Enterobacteriaceae: Centers for Disease Control and Prevention National Healthcare Safety Network (NHSN) annual survey, 2015 and 2016." Infection Control & Hospital Epidemiology 39, no. 9 (2018): 1115–17. http://dx.doi.org/10.1017/ice.2018.153.

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AbstractWe analyzed clinical microbiology laboratory practices for detection of multidrug-resistant Enterobacteriaceae in US short-stay acute-care hospitals using data from the National Healthcare Safety Network (NHSN) Annual Facility Survey. Half of hospitals reported testing for carbapenemases, and 1% performed routine polymyxin susceptibility testing using reference broth microdilution.

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Thesia, Naomi, Aswin Khairullah, Mustofa Effendi, et al. "<b>Detection of multidrug resistant <i>Klebsiella pneumoniae</i> isolated from duck cloacal swab in Jombang, Indonesia</b>." Open Veterinary Journal 15, no. 1 (2025): 300. https://doi.org/10.5455/ovj.2025.v15.i1.28.

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Background: Klebsiella pneumoniae bacteria is one of the pathogens that are often found in poultry and can cause various diseases in animals and humans. Currently, there are many reports of increasing multidrug resistance (MDR) K. pneumoniae showing including carbapenems, extended spectrum beta-lactamase (ESBL) and fluoroquinolones. Aim: The purpose of this study was to determine the antibiotic resistance pattern and the presence of multidrug resistance Klebsiella pneumoniae isolates isolated from duck cloacal swabs taken from duck farms in three different sub-districts, namely Paras sub-distr

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Nguyen Thi, Phu, Trinh Nguyen Thi Doan, and Hoa Hoang Thi Minh. "Assessment of the Antibiotic Resistance Characteristics of Staphylococcus aureus Isolated at Da Nang Hospital for Women and Children, Vietnam." Ramathibodi Medical Journal 46, no. 4 (2023): 42–51. http://dx.doi.org/10.33165/rmj.2023.46.4.266177.

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Background: Infections caused by multidrug-resistant Staphylococcus aureus (S. aureus), typically from methicillin-resistant S. aureus (MRSA) have become a global problem, including Vietnam. Objectives: To assess the prevalence of S. aureus infections, pathogenic characteristics, and evaluate antibiotic resistance profiles. Methods: This was a cross-sectional descriptive study of 191 S. aureus isolates cultured from clinical samples with antibiotic resistance profiles at the Department of Microbiology, Da Nang Hospital for Women and Children, Vietnam, from July 2021 to September 2022. Strain i

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Epifanova, Natalia Yu. "Modern approaches to the treatment of infections caused by Pseudomonas aeruginosa with multiple antimicrobial resistance. What a practicing physician should know." Supportive Therapy in Oncology 2, no. 2 (2025): 44–60. https://doi.org/10.17650/3034-2473-2025-2-2-44-60.

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The rise of antimicrobial resistance is a pressing problem worldwide. Oncology patients are at risk of developing infections caused by multidrug-resistant bacteria. This is associated with frequent visits of patients to hospitals for chemotherapy courses, long periods of neutropenia in oncohematologic patients and after hematopoietic stem cell transplantation, repeated courses of antibiotic therapy, surgical interventions, etc.Aim of this work – to familiarize physicians with the mechanisms of antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa), the possibilities and limitations

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Uddin, Bhuiyan Mohammad Mahtab, Md Anisur Rahman, Mst Marufa Yeasmin, Mosfika Mahjabin, Sarowar Jahan Chowdhury, and Iftikhar Ahmed. "Epidemiology, Clinical Conditions, Pathogenesis and Mechanism of Resistant of Acinetobacter baumannii: A Narrative Review." Bangladesh Journal of Medical Microbiology 17, no. 2 (2023): 88–92. http://dx.doi.org/10.3329/bjmm.v17i2.69197.

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The world is facing a growing threat from multidrug-resistant (MDR) gram negative “superbugs,” such as Acinetobacter baumannii. This morbidity and mortality loss caused there of indirectly hampers the economic developments in countries. These multidrug-resistant A. baumannii worldwide represents a major public health problem. The development of antibiotics decreased the mortality among the human and animals leading to a better life expectancy. But the injudicious use of antimicrobials and selection pressure the microbes have developed resistance which became more prominent during last few deca

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Cantón, Rafael, and Patricia Ruiz-Garbajosa. "Treatment guidelines for multidrug-resistant Gram-negative microorganisms." Revista Española de Quimioterapia 36, Suppl1 (2023): 46–51. http://dx.doi.org/10.37201/req/s01.11.2023.

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In recent years, new antimicrobials have been introduced in therapeutics, including new beta-lactam-beta-lactamase inhibitor combinations and cefiderocol in response to therapeutic needs in the face of increasing resistance. There are also different treatment guidelines for infections caused by these microorganisms that have been approved by different professional societies, including those of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), the Infectious Disease Society of America (IDSA) and the Spanish Society of Infectious Diseases and Clinical Microbiology (

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Ghimire, Lata, Megha Raj Banjara, and Abdelkodose Mohammed Hussen Abdulla. "Assessing Tetracycline susceptibility in multidrug-resistant Staphylococcus aureus: A clinical study in Kathmandu." Patan Pragya 12, no. 02 (2023): 46–54. http://dx.doi.org/10.3126/pragya.v12i02.64198.

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Introduction: Staphylococcus aureus, recognized as an opportunistic pathogen, is frequently implicated in diverse human infections. Managing multidrug-resistant S. aureus poses a significant challenge in the clinical sector. Beyond B-lactam antibiotics, healthcare practitioners commonly prescribe Glycopeptides, Tetracycline, Quinolones, and Macrolide-Lincosamide-Streptogramin B antibiotics as alternative treatments for such infections. Consequently, this study was undertaken to evaluate the susceptibility of multidrug-resistant S. aureus to tetracycline in clinical samples. Methods: The study

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Idris, A. H., Z. Haruna, M. Y. Iliyasu, et al. "Antibacterial Activity of Lawsonia inermis Leaf Extracts against Multidrug-resistant Pseudomonas aeruginosa from Infected Wounds." European Journal of Medicinal Plants 34, no. 4 (2023): 1–8. http://dx.doi.org/10.9734/ejmp/2023/v34i41130.

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Background: Wound infection comprises numerous different organisms that have the ability to surface colonization of wounds. Multidrug-resistant Pseudomonas aeruginosa is one of the pathogenic bacteria associated with wound infections. Aim: This study isolated and identified multidrug-resistant Pseudomonas aeruginosa from infected wounds and determine the antibacterial activity of Lawsonia inermis leaf extracts against it. Design: This is a Clinical and laboratory-based study involving patients with defined cases of wound infections. Place and Duration of Study: This study was

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Kumar, Shashi B., Shanvanth R. Arnipalli, and Ouliana Ziouzenkova. "Antibiotics in Food Chain: The Consequences for Antibiotic Resistance." Antibiotics 9, no. 10 (2020): 688. http://dx.doi.org/10.3390/antibiotics9100688.

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Antibiotics have been used as essential therapeutics for nearly 100 years and, increasingly, as a preventive agent in the agricultural and animal industry. Continuous use and misuse of antibiotics have provoked the development of antibiotic resistant bacteria that progressively increased mortality from multidrug-resistant bacterial infections, thereby posing a tremendous threat to public health. The goal of our review is to advance the understanding of mechanisms of dissemination and the development of antibiotic resistance genes in the context of nutrition and related clinical, agricultural,

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Brungi, Sravanthi, Sreeja Vamsi Kogila, Ramachandra Reddy Bhumi Reddy, Shaheen Sultana, and Manisha Singh. "Phenotypic detection of extended spectrum beta lactamase and metallo beta lactamase producers among multidrug resistant Escherichia coli and Klebsiella spp. in urinary tract infections." IP International Journal of Medical Microbiology and Tropical Diseases 9, no. 4 (2024): 246–52. http://dx.doi.org/10.18231/j.ijmmtd.2023.047.

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: The incidence of Urinary tract infection (UTI) concomitantly causing the morbidity and mortality in patients with specific risk factors is highly alarming. () and spp., are the most frequently isolated species and considered as highly significant due to their ability to produce Extended spectrum beta lactamase (ESBL) and Metallo beta lactamase (MBL). UTIs caused by bacteria that produces ESBL and MBL are becoming more common, and the ability of diagnostic microbiology laboratories to promptly screen for and identify these resistant infections is crucial.The main objective of my study is to i

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Sapkota, Jyotshna, Manisha Sharma, Deepti Shrestha, and Beena Jha. "Antimicrobial Susceptibility Pattern of Acinetobacter calcoaceticus-Acinetobacter baumannii Complex Isolated from Sputum in a Tertiary Care Hospital." Journal of Institute of Medicine Nepal 41, no. 3 (2019): 59–62. http://dx.doi.org/10.3126/jiom.v41i3.37367.

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Introduction Acinetobacter calcoaceticus-Acinetobacter baumanni (ACB) complex is one of the commonest cause of hospital acquired and ventilator associated pneumonia. Multidrug resistant Acinetobacter species have become a matter of huge concern. This study was done to find out the antibiotic susceptibility pattern of Acinetobacter calcoaceticus-Acinetobacter baumanii complex from sputum samples. MethodsThis descriptive cross-sectional study was carried out in Clinical Microbiology laboratory from July 2018 to Jan 2019 after ethical approval. Acinetobacter calcoaceticus-Acinetobacter baum

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Sapkota, Jyotshna, Manisha Sharma, Deepti Shrestha, and Beena Jha. "Antimicrobial Susceptibility Pattern of Acinetobacter calcoaceticus-Acinetobacter baumannii Complex Isolated from Sputum in a Tertiary Care Hospital." Journal of Institute of Medicine Nepal 41, no. 3 (2019): 59–62. http://dx.doi.org/10.59779/jiomnepal.1064.

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Introduction: Acinetobacter calcoaceticus-Acinetobacter baumanni (ACB) complex is one of the commonest cause of hospital acquired and ventilator associated pneumonia. Multidrug resistant Acinetobacter species have become a matter of huge concern. This study was done to find out the antibiotic susceptibility pattern of Acinetobacter calcoaceticus-Acinetobacter baumanii complex from sputum samples. Methods: This descriptive cross-sectional study was carried out in Clinical Microbiology laboratory from July 2018 to Jan 2019 after ethical approval. Acinetobacter calcoaceticus-Acinetobacter baumann

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Shrestha, S., T. Tada, B. Shrestha та ін. "Phenotypic characterization of multidrug-resistant Acinetobacter baumannii with special reference to metallo-β-lactamase production from the hospitalized patients in a tertiary care hospital in Nepal." Journal of Institute of Medicine Nepal 37, № 3 (2015): 3–10. http://dx.doi.org/10.59779/jiomnepal.694.

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Introduction: Acinetobacter baumanniiis an important cause of nosocomial infection and has been associated with a wide variety of illnesses in hospitalized patients, especially patients in the intensive care units. The emergence of carbapenem-resistant clones of A. baumannii has been the most serious problem worldwide. After the carbapenem resistant clones have emerged, leaving the hope of treatment of A. baumannii infection is by the last resort of antibiotics such as tigecycline, polymyxin-B and colistin. The purpose of this study is to determine the antibiotic resistance patterns of A. baum

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Boyanova, Lyudmila, Rumyana Markovska, and Ivan Mitov. "Multidrug resistance in anaerobes." Future Microbiology 14, no. 12 (2019): 1055–64. http://dx.doi.org/10.2217/fmb-2019-0132.

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Multidrug resistance (MDR) in anaerobes is not a well-known topic. Bacteroides fragilis group isolates have numerous resistance determinants such as multidrug efflux pumps, cfiA and nimB genes and activating insertion sequences, and some isolates exhibited extensive drug-resistant patterns. MDR rates in B. fragilis group were from 1.5 to >18% and up to >71% in cfiA and nimB positive isolates carrying insertion sequences. MDR was present in >1/2 of Clostridioides difficile isolates, most often in epidemic/hypervirulent strains and unusually high metronidazole or vancomycin resistance h

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OYEDUM, U. M., O. S. OLATUNJI, and H. ABU. "ISOLATION AND CHARACTERISATION OF MULTI DRUG-RESISTANT BACTERIA FROM SURGICAL EQUIPMENTS IN GENERAL HOSPITAL." African Journal of Health, Safety and Environment 4, no. 1 (2023): 59–64. http://dx.doi.org/10.52417/ajhse.v4i1.393.

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The predominance of acquired resistance, especially multidrug-resistance among bacterial isolates is fast becoming a major menace associated with health-care equipments and facilities. Samples were collected from four (4) surfaces of various surgical equipments such as operating tables, trolleys, beds and drip stands in the surgical theatre in General Hospital Minna. The samples were collected using sterile swab sticks dipped in normal saline and were transported to the Microbiology laboratory at Federal University of Technology Minna for further analysis. Samples were inoculated on various cu

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Mogen, Austin B., and Kelly C. Rice. "Why We Should Be Concerned about Methicillin-Resistant Staphylococcus aureus (MRSA)." EDIS 2016, no. 1 (2016): 6. http://dx.doi.org/10.32473/edis-mb006-2015.

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Treatment and complete resolution of MRSA infections can be extremely challenging, since many MRSA strains are multidrug-resistant. This 6-page fact sheet provides an overview of MRSA, different strains, risk factors, symptoms, prevention, and the pathogen’s effects on human health and agriculture. Written by Austin B. Mogen and Kelly C. Rice, and published by the UF Department of Microbiology and Cell Science, September 2015.

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Gordon, Louisa G., Thomas M. Elliott, Brian Forde, et al. "Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia." BMJ Open 11, no. 2 (2021): e041968. http://dx.doi.org/10.1136/bmjopen-2020-041968.

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ObjectiveTo predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens compared with those of standard of care.DesignBudget impact analysis was performed over the following 5 years. Data were primarily from sequencing results on clusters of multidrug-resistant organisms across 27 hospitals. Model inputs were derived from hospitalisation and sequencing data, and epidemiological and costing reports, and included multidrug resistance rates and their trends.SettingQueensland, Australia.ParticipantsHospitalised patients.InterventionsWGS surveillance o

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Richter, Sandra S., and Daniel M. Musher. "The Ongoing Genetic Adaptation of Streptococcus pneumoniae." Journal of Clinical Microbiology 55, no. 3 (2016): 681–85. http://dx.doi.org/10.1128/jcm.02283-16.

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ABSTRACT Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724–734, 2017, https://doi.org/10.1128/JCM.01778-16 ) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

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Hussain, Ashfaq, Muhammad Farooq, Muhammad Luqman Satti, Faisal Hanif, Saba Sarwar, and Fatima Sana. "Continuous Threat of Growing Antimicrobial Resistance Among Salmonella Typhi Isolates: A Multicenter Study from Pakistan." Pakistan Armed Forces Medical Journal 74, no. 6 (2024): 1531–35. https://doi.org/10.51253/pafmj.v74i6.8977.

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Objective: To determine current susceptibility patterns of Salmonella enterica serovar Typhi (S. Typhi) in four cities of Pakistan and to deduce the frequency of multidrug resistant, extensively drug-resistant S. Typhi. Study Design: Cross-sectional study. Place and Duration of Study: Departments of Microbiology, Pakistan Navy Ship Shifa Hospital, Karachi, Pak Emirates Military Hospital, Rawalpindi, Combined Military Hospital, Sialkot, Combined Military Hospital, Abbottabad, Pakistan, from Apr 2019 to Sep 2020. Methodology: Blood culture specimens of patients with suspected Enteric fever from

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Ali, M1* Gambo S1 Zage A.U2 Baba A.M3 and Adamu SM4. "Determination of Extended Spectrum Beta-lactamase (ESBL) Producing Enterobacteriaceae from Children infected with Diarrhea in Kano, Northern Nigeria." MSI Journal of Medicine and Medical Research (MSIJMMR) Volume 2, Issue 5 (2025): 01–14. https://doi.org/10.5281/zenodo.15383206.

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Diseases caused by microorganisms are currently causes of morbidity and motility worldwide. The study was aimed to determine the prevalence of extended spectrum beta lactamase producing Enterobacteriaceae isolate from children infected with diarrhea in Kano, Northern Nigeria. Two hundred and fifty (250) stool samples of the infected children were obtained from Microbiology department of Murtala Muhammad Specialist Hospital. Multidrug resistant (MDR) isolates were determined using disc diffusion method. The multidrug resistant isolates were evaluated using antibiotic disc of ceftriaxone and cef

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Ojewuyi, AR, OO Ojewuyi, TA Bamikefa, et al. "Multidrug-Resistant Clinical Infections; Results from a Point Prevalence Study in a Tertiary Resource-Limited Hospital, SouthWest Nigeria." WESTERN JOURNAL OF MEDICAL AND BIOMEDICAL SCIENCES 6, no. 1 (2025): 36–42. https://doi.org/10.5281/zenodo.15158881.

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ABSTRACT Multidrug-resistant (MDR) infections are on the rise globally, often exhibiting significant geographical variability and posing a great threat especially in the low- and middle-income countries. We aimed at investigating the prevalence and patterns of MDR clinical infections in our local Hospital. This was a point prevalence study involving admitted patients in our hospital, following routine sample processing, data was extracted from the microbiology processing forms and clinical files of the patients using a well-structured proforma. Ethical approval was sought and obtained for the

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Tayyab, Nadia, Warda Furqan, Amnah Nasrullah, Javaid Usman, Sakhawat Ali, and Asad Zaman Khan. "MDR BACTERIAL INFECTIONS IN CRITICALLY ILL COVID-19 PATIENTS IN A TERTIARY CARE HOSPITAL (OF PAKISTAN)." PAFMJ 71, no. 3 (2021): 1027–32. http://dx.doi.org/10.51253/pafmj.v71i3.5478.

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Objective: To identify antimicrobial susceptibility pattern of multidrug resistant bacteria causing secondary infections in COVID-19 patients in ICU’ sofa tertiary care hospital. Study Design: Cross–sectional study. Place and Duration of Study: Department of Microbiology, Pak Emirates Military Hospital, Rawalpindi, from Apr to Jul 2020. Methodology: This study included blood samples and endotracheal aspirates from 114 critically ill COVID-19 patients. Peripheral blood specimens were collected fromthe patients with secondary bacterial blood stream infections and endotracheal a

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Kakati, Barnali, Nupur Koul, Sonika Agarwal, and Garima Mittal. "Multidrug resistant Acinetobacter baumannii causing Ventilator associated respiratory infections at a tertiary care center of India." IP International Journal of Medical Microbiology and Tropical Diseases 8, no. 1 (2022): 15–18. http://dx.doi.org/10.18231/j.ijmmtd.2022.004.

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A rise in Multidrug resistant causing ventilator-associated respiratory infections (VARIs) is posing a therapeutic challenge for physicians and diagnosticians worldwide. Timely detection and reporting of these robust multidrug resistant (MDR) pathogens would be useful in not only guiding an appropriate empirical therapy but also in controlling the spread of these drug resistant strains in the ICUs and hospital. : To detect in Endotracheal secretions of suspected cases of Ventilator-associated respiratory infections (VARIs) and report the antimicrobial sensitivity pattern for the same. : Observ

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Oyedum, U. M., and J. Agbala. "The study of multidrug resistant bacteria from locally produced tiger nut drinks (Kunuaya) sold in Minna, Niger State." Scientia Africana 21, no. 2 (2022): 91–96. http://dx.doi.org/10.4314/sa.v21i2.9.

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The predominance of multidrug resistant (MDR) bacteria among the populace, edible foods and drinks is fast becoming the major concern in most communities. Three (3) locally prepared drinks from three locations were aseptically collected and transported to the Microbiology Laboratory of Federal University of Technology, Minna. Samples were serially diluted and were inoculated on various media through the spread plate method. The bacterial isolates were identified based on their Gram reaction and other biochemical tests. The antibiotic susceptibility tests were carried out for the bacterial isol

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Uche, Mary Okoye, and Anthony Okafor Kelechi. "Prevalence of Multi-Drug Resistant Bacteria Associated With Various Yoghurt Products Commonly Sold in Minna, North Central, Nigeria." Journal of Science and Technology (Ghana) 41, no. 3 (2023): 68–76. https://doi.org/10.4314/just.v41i3.6.

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The predominance of Multidrug resistant (MDR) bacteria among dairy products especially yoghurt is fast becoming a major concern in most communities. Five (5) industrially prepared yoghurts were aseptically collected and transported to the Microbiology Laboratory of Federal University of Technology, Minna. Samples were serially diluted and inoculated on various media through the pour plate method. The bacterial isolates were identified through their Gram reaction and other biochemical tests. The antibiotic susceptibility tests were carried out using the disc diffusion method on Muller Hinton ag

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Kaur, Kiranjeet, and Shavetika Jindal. "Bacteriological profile and antimicrobial susceptibility pattern of endotracheal tube secretion of patients in ICUs of a tertiary care hospital in Punjab." Indian Journal of Microbiology Research 8, no. 3 (2021): 224–29. http://dx.doi.org/10.18231/j.ijmr.2021.046.

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Healthcare associated pneumonia (HAP)is second most common HCAIs that occur in 27% critically ill patients. Eighty-six percent of HAP are associated with mechanical ventilation and termed as ventilator associated pneumonia (VAP). VAP due to multidrug resistant has also increased in recent past. To isolate and identify the bacterial pathogens in endotracheal tubes aspirates of ICUs patients and study their antimicrobial susceptibility pattern.A prospective longitudinal study was conducted in the Microbiology laboratory of a tertiary care hospital over a period of six months after clearance from

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Noster, Janina, Philipp Thelen, and Axel Hamprecht. "Detection of Multidrug-Resistant Enterobacterales—From ESBLs to Carbapenemases." Antibiotics 10, no. 9 (2021): 1140. http://dx.doi.org/10.3390/antibiotics10091140.

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Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health, leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly caused by different β-lactamases (e.g., ESBLs and carbapenemases), sometimes in combination with other resistance mechanisms (e.g., porin loss, efflux). The continuous spread of MDRE among patients in hospital settings and the healthy population require adjustments in healthcare management and routine diagnostics. Rapid and reliable detection of MDRE infections as well as gastrointestinal colonization is key to guide

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Ikram, Amna, Sidrah Saleem, Muhammad Imran, and Ayesha Ghazal. "Antimicrobial activity by solvents extracted from Ocimum basilicum herb against multidrug resistant gram negative rods." Journal of Islamabad Medical & Dental College 10, no. 4 (2021): 200–205. http://dx.doi.org/10.35787/jimdc.v10i4.673.

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ABSTRACT: Background: Failure of treatment with antibiotics occurs due to increase in number of Multidrug resistant gram negative bacteria, worldwide. The objective of this study was to find out the antimicrobial activity of crude ethanolic extract and its further three fractions by Ocimum basilicum leaves against multi drug resistant gram negative rods. Material and Methods: This descriptive study was conducted in the Department of Microbiology, University of Health Sciences, Lahore from 1st july 2016 to 30th june 2017. Total 80 multidrug resistant gram negative rods were included

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Aswathi, K. P., B. J. Deepthy, Gogi Suresh, P. V. Harish, and U. V. Deepthy. "Prospective Study on Microbiology of Respiratory Tract Infections with Interest in Multidrug Resistant Bacteria." International Journal of Current Microbiology and Applied Sciences 5, no. 12 (2016): 291–94. http://dx.doi.org/10.20546/ijcmas.2016.512.031.

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Yadav, Poonam, Shyam Kumar Mishra, Sreska Shrestha, et al. "Multidrug-Resistance and Biofilm Formation among Acinetobacter baumannii Isolated from Clinical Specimens." Journal of Nepal Health Research Council 22, no. 04 (2025): 662–69. https://doi.org/10.33314/jnhrc.v22i04.4694.

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Background: Acinetobacter baumannii has emerged as a problematic pathogen due to its ability to become resistant to antibiotics and form biofilms. The aim of this study was to explore antibiotic resistance and biofilm formation, and examine any correlation between these in Acinetobacter baumannii isolates.Methods: This was a cross-sectional study conducted at the 750-bed Tribhuvan University Teaching Hospital in Nepal. Identification and antibiotic sensitivity of Acinetobacter baumannii isolates were performed following American Society for Microbiology guidelines. Different β-lactamases were

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Savage, Victoria J., Cédric Charrier, Anne-Marie Salisbury, et al. "Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection." Antimicrobial Agents and Chemotherapy 60, no. 9 (2016): 5592–94. http://dx.doi.org/10.1128/aac.00913-16.

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ABSTRACTThere is an urgent need for new antibiotics to treat multidrug-resistantNeisseria gonorrhoeae. In this report, the microbiology,in vivopharmacokinetics, and efficacy of REDX05931, a representative novel tricyclic topoisomerase inhibitor, were evaluated. REDX05931 demonstrated high oral bioavailability in mice and reducedN. gonorrhoeaeinfection after a single dose in a mouse model of gonorrhea. These data support the potential of this series of small molecules as a new treatment for drug-resistant gonorrheal infections.

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O., Oluyele, and K. Oladunmoye M. "Antibiotics Susceptibility Patterns and Plasmid Profile of Staphylococcus aureus Isolated from Patients with Wound Infections Attending Four Hospitals in Akure, Ondo State." Journal of Advances in Microbiology 3, no. 4 (2017): 1–8. https://doi.org/10.9734/JAMB/2017/33879.

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<strong>Aims:</strong> Several studies have documented <em>Staphylococcus aureus</em> as a leading pathogen implicated in wound infections with a remarkable potential for antibiotics resistance. This study determined the susceptibility patterns of <em>S. aureus</em> isolated from wound infections to conventional antibiotics and assessed the plasmid profile of selected multidrug resistant isolates. <strong>Study Design:</strong> This study was designed to determine the antibiotics susceptibility patterns of <em>Staphylococcus aureus</em> isolates from wound infections. <strong>Place and Duratio

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Afroz, Fatima, Shaheda Anwar, Mashrura Quraishi, GM Mohiuddin, SM Ali Ahmed, and Ahmed Abu Saleh. "Antimicrobial Resistance Pattern of Extensively Drug Resistant Carbapenemase Producing Enterobacteriaceae." Bangladesh Journal of Medical Microbiology 13, no. 2 (2019): 7–10. http://dx.doi.org/10.3329/bjmm.v13i2.51786.

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Carbapenems, often agents of last resort for multidrug resistant bacterial infections are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Production of carbapenemases remain the most clinically important mechanism of carbapenem resistance in Enterobacteriaceae. The objective of this study was to determine the antibiogram pattern of carbapenemase producing Enterobacteriaceae. A cross sectional study was conducted at department of Microbiology and Immunology, BSMMU from September 2018 to August 2019. A total of 145 CRE isolates from different clinical

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Rizwan, Muhammad, Habib Ullah, Anjala Ayoub, et al. "Prevalence and Antimicrobial Susceptibility Pattern of Enterobacteriaceae Isolated from Hospitals Wastewater." Pakistan Journal of Medical and Health Sciences 16, no. 11 (2022): 459–64. http://dx.doi.org/10.53350/pjmhs20221611459.

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Background: Hospital wastewater (HWW) is bearing in mind the main root to proliferate multidrug-resistant among the Enterobacteriaceae family. Enterobacteriaceae is suited to be a considerable risk for antibiotic-resistant through CTX-M production which is observed as an important factor leading to multiple drug-resistant. Study Design: A total of 100 samples of HWW and community wastewater were collected aseptically. Samples were sub-cultured through basic, selective, and UTI Chrome agar. Place of the study: This research was conducted in the Postgraduate Research Laboratory of the Department

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Lata, Patel, Rathod Sanjay, Bhavasar Toral, Rajput Anil, Chauhan Sunny, and Kadam Mina. "Study of Carbapenem Resistant Klebsiella Pneumoniae in a Tertiary Care Hospital in Ahmedabad." International Journal of Current Pharmaceutical Review and Research 15, no. 10 (2023): 261–67. https://doi.org/10.5281/zenodo.11630317.

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AbstractIntroduction: Enterobacteriaceae that produce resistant to carbapenem are becoming an increasing problemworldwide. Carbapenems were the choice for the therapeutic management of multidrug resistant gram negativebacterial infections. Due to a shortage of alternative medicines, multidrug-resistant (MDR) and carbapenemresistant Klebsiella pneumoniae have become major therapeutic challenges in various countries.Material &Method: The retrospective study was conducted in the department of Microbiology, Narendra Modimedical college, Ahmedabad, Gujarat over a period of one year i.e. from Ja

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Begum, Nurjahan, and S. M. Shamsuzzaman. "Emergence of multidrug resistant and extensively drug resistant community acquired uropathogens in Dhaka city, Bangladesh." Bangladesh Journal of Medical Microbiology 9, no. 2 (2017): 7–12. http://dx.doi.org/10.3329/bjmm.v9i2.31414.

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Because of indiscriminate, inadequate and irrational usage of antimicriobials, the sensitivity pattern of community acquired uropathogens is changing drastically, specifically in developing countries, such as Bangladesh. This study was undertaken to investigate the profile of common uropathogens in community settings and to evaluate their antimicrobial resistance profile in order to categorize them into multidrug resistant (MDR), extensively drug resistant (XDR) and pandrug resistant (PDR) organisms.Total 800 urine samples were collected from symptomatic UTI cases and processed in the Departme

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