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Relevant bibliographies by topics / Multiple endpoints

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Academic literature on the topic 'Multiple endpoints'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "Multiple endpoints"

1

Chi, George Y. H. "Multiple Testings: Multiple Comparisons and Multiple Endpoints." Drug Information Journal 32, no. 1_suppl (1998): 1347S—1362S. http://dx.doi.org/10.1177/00928615980320s131.

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Dueck, Amylou, Paul J. Novotny, and Jeff A. Sloan. "Dealing with Multiple Endpoints." Current Problems in Cancer 30, no. 6 (2006): 298–306. http://dx.doi.org/10.1016/j.currproblcancer.2006.08.007.

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Häberle, Lothar, Annette Pfahlberg, and Olaf Gefeller. "Assessment of Multiple Ordinal Endpoints." Biometrical Journal 51, no. 1 (2009): 217–26. http://dx.doi.org/10.1002/bimj.200810502.

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Hasler, Mario, and Kathrin Böhlendorf. "Multiple Comparisons for Multiple Endpoints in Agricultural Experiments." Journal of Agricultural, Biological, and Environmental Statistics 18, no. 4 (2013): 578–93. http://dx.doi.org/10.1007/s13253-013-0149-7.

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Tsai, Kao-Tai, and James A. Kozial. "Assessing multiple endpoints with ordered alternatives." Communications in Statistics - Theory and Methods 23, no. 2 (1994): 533–44. http://dx.doi.org/10.1080/03610929408831270.

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Xu, Jane, and Scott L. Zeger. "The Evaluation of Multiple Surrogate Endpoints." Biometrics 57, no. 1 (2001): 81–87. http://dx.doi.org/10.1111/j.0006-341x.2001.00081.x.

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Eaton, Morris L., and Robb J. Muirhead. "On a multiple endpoints testing problem." Journal of Statistical Planning and Inference 137, no. 11 (2007): 3416–29. http://dx.doi.org/10.1016/j.jspi.2007.03.021.

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Quan, Hui, Jim Bolognese, and Weiying Yuan. "Assessment of equivalence on multiple endpoints." Statistics in Medicine 20, no. 21 (2001): 3159–73. http://dx.doi.org/10.1002/sim.985.

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Ishihara, Takuma, and Kouji Yamamoto. "A Test for Multiple Binary Endpoints with Continuous Latent Distribution in Clinical Trials." Journal of Statistical Theory and Applications 20, no. 4 (2021): 463–80. http://dx.doi.org/10.1007/s44199-021-00003-3.

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AbstractIn clinical trials, two or more binary responses obtained by dichotomizing continuous responses are often employed as multiple primary endpoints. Testing procedures for multiple binary variables with latent distribution have not yet been adequately discussed. Based on the association measure among latent variables, we provide a statistic for testing the superiority of at least one binary endpoint. In addition, we propose a testing procedure with a framework in which the trial efficacy is confirmed only when there is superiority of at least one endpoint and non-inferiority of the remain

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Wei, Xinmiao, Tengxin Huang, Zhijiang Yang, Li Pan, Liangliang Wang, and Junjie Ding. "Quantitative Predictive Studies of Multiple Biological Activities of TRPV1 Modulators." Molecules 29, no. 2 (2024): 295. http://dx.doi.org/10.3390/molecules29020295.

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TRPV1 channel agonists and antagonists, which have powerful analgesic effects without the addictive qualities associated with traditional analgesics, have become a focus area for the development of novel analgesics. In this study, quantitative structure–activity relationship (QSAR) models for three bioactive endpoints (Ki, IC50, and EC50) were successfully constructed using four machine learning algorithms: SVM, Bagging, GBDT, and XGBoost. These models were based on 2922 TRPV1 modulators and incorporated four types of molecular descriptors: Daylight, E-state, ECFP4, and MACCS. After the rigoro

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Dissertations / Theses on the topic "Multiple endpoints"

1

Liu, Yi. "Testing for Efficacy for Primary and Secondary Endpoints by Partitioning Decision Paths." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1259598621.

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James, Susan Elizabeth. "The analysis of multiple endpoints in clinical trials." Thesis, University of Leicester, 1993. http://hdl.handle.net/2381/34548.

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Zain, Zakiyah. "Combining multiple survival endpoints within a single statistical analysis." Thesis, Lancaster University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618302.

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The aim of this thesis is to develop methodology for combining multiple endpoints within a single statistical analysis that compares the responses of patients treated with a novel treatment with those of control patients treated conventionally. The focus is on interval-censored bivariate survival data, and five real data sets from previous studies concerning multiple responses are used to illustrate the techniques developed. The background to survival analysis is introduced by a general description of survival data, and an overview of existing methods and underlying models is included. A revie

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Pallmann, Philip Steffen [Verfasser]. "Multiple contrast tests with repeated and multiple endpoints : with biological applications / Philip Steffen Pallmann." Hannover : Technische Informationsbibliothek (TIB), 2016. http://d-nb.info/1112948635/34.

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Ntambwe, Lupetu Ives. "Sequential sample size re-estimation in clinical trials with multiple co-primary endpoints." Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/66339/.

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In this thesis, we consider interim sample size adjustment in clinical trials with multiple co-primary continuous endpoints. We aim to answer two questions: First, how to adjust a sample size in clinical trial with multiple continuous co-primary endpoints using adaptive and group sequential design. Second, how to construct a test in order to control the family-wise type I error rate and maintain the power, even if the correlation ρ between endpoints is not known. To answer the first question, we conduct K different interim tests, each for one endpoint and each at level α/K (i.e. Bonferroni adj

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Nyirabahizi, Epiphanie. "Bayesian and Frequentist Approaches for the Analysis of Multiple Endpoints Data Resulting from Exposure to Multiple Health Stressors." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/136.

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In risk analysis, Benchmark dose (BMD)methodology is used to quantify the risk associated with exposure to stressors such as environmental chemicals. It consists of fitting a mathematical model to the exposure data and the BMD is the dose expected to result in a pre-specified response or benchmark response (BMR). Most available exposure data are from single chemical exposure, but living objects are exposed to multiple sources of hazards. Furthermore, in some studies, researchers may observe multiple endpoints on one subject. Statistical approaches to address multiple endpoints problem can be p

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Farhat, Naha. "Design and Analysis of Toxicological Experiments with Multiple Endpoints and Synergistic and Inhibitory Effects." VCU Scholars Compass, 2014. https://scholarscompass.vcu.edu/etd/636.

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The enormous increase of exposure to toxic materials and hazardous chemicals in recent years is a major concern due to the adverse effect resulting from such exposure on human health specifically and all organisms in general. Among the major concerns of toxicologists is to determine an acceptable level(s) of exposure to such hazardous substance(s). Current approaches often evaluate each endpoint and stressor individually. Herein we propose two novel approaches to simultaneously determine the Benchmark Dose Tolerable Region (BMDTR) for multiple endpoints and multiple stressors studies when stre

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Walker, Ann Sarah. "The analysis of multivariate failure time data with application to multiple endpoints in trials in HIV infection." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390624.

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Hieke-Schulz, Stefanie [Verfasser], and Martin [Akademischer Betreuer] Schumacher. "Statistical modeling strategies for linking multiple molecular sources to time-to-event endpoints = Statistische Modellbildungsstrategien zur Verknüpfung multipler molekularer Quellen unter Berücksichtigung von Time-to-Event Endpunkten." Freiburg : Universität, 2014. http://d-nb.info/1123480672/34.

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Riou, Jérémie. "Multiplicité des tests, et calculs de taille d'échantillon en recherche clinique." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22066/document.

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Ce travail a eu pour objectif de répondre aux problématiques inhérentes aux tests multiples dans le contexte des essais cliniques. A l’heure actuelle un nombre croissant d’essais cliniques ont pour objectif d’observer l’effet multifactoriel d’un produit, et nécessite donc l’utilisation de co-critères de jugement principaux. La significativité de l’étude est alors conclue si et seulement si nous observons le rejet d’au moins r hypothèses nulles parmi les m hypothèses nulles testées. Dans ce contexte, les statisticiens doivent prendre en compte la multiplicité induite par cette pratique. Nous no

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Books on the topic "Multiple endpoints"

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22005-5.

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer, 2015.

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer London, Limited, 2015.

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Freitag, Lisa. Defining Extreme Caregiving. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190491789.003.0002.

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To emphasize the complexity and difficulty of parenting a child with special needs, this chapter introduces and defines the term “extreme caregiving.” Extreme caregiving involves the taking on of professional medical roles by a nonprofessional parent. It differs from both ordinary parenting and professional caregiving in that it is done in the home, often without respite or foreseeable endpoint. Unlike professional caregiving, it involves an intense personal relationship between parent and child. The need for extreme caregiving extends through multiple pediatric syndromes and disabling conditi

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Book chapters on the topic "Multiple endpoints"

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Bretz, Frank, and Michael Branson. "Multiple Endpoints." In Methods and Applications of Statistics in Clinical Trials. John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118596005.ch46.

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Wang, Bushi. "Multiple Endpoints." In Handbook of Multiple Comparisons. Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9780429030888-12.

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Cleophas, Ton J., and Aeilko H. Zwinderman. "Multiple Endpoints." In Machine Learning in Medicine. Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-7869-6_4.

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Crespi, Catherine M. "Multiple primary endpoints." In Power and Sample Size in R. Chapman and Hall/CRC, 2024. https://doi.org/10.1201/9780429488788-17.

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. "Continuous Primary Endpoints." In Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22005-5_5.

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Moyé, Lemuel A. "Multiple Testing and Combined Endpoints." In Statistical Reasoning in Medicine. Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-46212-7_10.

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. "Continuous Co-primary Endpoints." In Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22005-5_2.

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Sozu, Takashi, Tomoyuki Sugimoto, Toshimitsu Hamasaki, and Scott R. Evans. "Binary Co-primary Endpoints." In Sample Size Determination in Clinical Trials with Multiple Endpoints. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22005-5_3.

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Glimm, Ekkehard, Dong Xi, and Paul Gallo. "Multiple Comparisons, Multiple Primary Endpoints and Subpopulation Analysis." In Textbook of Clinical Trials in Oncology. Chapman and Hall/CRC, 2019. http://dx.doi.org/10.1201/9781315112084-10.

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Hamasaki, Toshimitsu, Yuh-Jenn Wu, and Chin-Fu Hsiao. "Multiple Endpoints in Multiregional Clinical Trials." In Simultaneous Global New Drug Development. Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781003109785-17.

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Conference papers on the topic "Multiple endpoints"

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Stevnsborg, Mads, Krist V. Gernaey, and Jakob K. Huusom. "Digital Shadow of a Pilot Scale Packed Batch Distillation Column for Real-Time Operator Training- and Support." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.182519.

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Digital twins and digital shadows are frequently used terms by industry and academia to describe data-centric models that accurately depict a physical system intended for process monitoring and control. Processes restricted by a low degree of automation rely greatly on operator competencies in key decision-making; a digital shadow can here assist as a guidance tool [1-4]. This work presents a practical implementation of a digital shadow to support operators running a pilot scale-packed batch distillation column at the Technical University of Denmark (DTU) primarily used in education and teachi

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Huynh, Dat, Oluwadare Badejo, Borja Hern�ndez, and Marianthi Ierapetritou. "Multi-Stakeholder Optimization for Identification of Relevant Life Cycle Assessment Endpoint Indicators." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.184670.

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Endpoint indicators provide a concise representation of environmental impacts by aggregating multiple midpoint indicators into a single value. Traditional endpoint weighting systems, however, are often limited by biases introduced through panel reviews and a lack of robustness in scientific process models. Additionally, they typically fail to account for the preferences of key stakeholders, including industry, government, and the public. This work addresses these limitations by developing an endpoint indicator that incorporates stakeholder preferences and minimizes dissatisfaction. A multi-sta

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Hamadanian, Pouya, Doug Gallatin, Mohammad Alizadeh, and Krishna Chintalapudi. "Ekho: Synchronizing cloud gaming media across multiple endpoints." In ACM SIGCOMM '23: ACM SIGCOMM 2023 Conference. ACM, 2023. http://dx.doi.org/10.1145/3603269.3604826.

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Meadows, Larry, Ken-Ichi Ishikawa, Taisuke Boku, and Masashi Horikoshi. "Multiple endpoints for improved MPI performance on a lattice QCD code." In HPC Asia 2018 WS: Workshops of HPC Asia 2018. ACM, 2018. http://dx.doi.org/10.1145/3176364.3176375.

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Ruhela, Amit, Bharath Ramesh, Sourav Chakraborty, Hari Subramoni, Jahanzeb Hashmi, and Dhabaleswar Panda. "Leveraging Network-level parallelism with Multiple Process-Endpoints for MPI Broadcast." In 2019 IEEE/ACM Third Annual Workshop on Emerging Parallel and Distributed Runtime Systems and Middleware (IPDRM). IEEE, 2019. http://dx.doi.org/10.1109/ipdrm49579.2019.00009.

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Becker, Daniel, Jens Einsiedler, Bernd Schaufele, Alexander Binder, and Ilja Radusch. "Identification of vehicle tracks and association to wireless endpoints by multiple sensor modalities." In 2013 International Conference on Indoor Positioning and Indoor Navigation (IPIN). IEEE, 2013. http://dx.doi.org/10.1109/ipin.2013.6817878.

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Zain, Zakiyah, and John Whitehead. "Survival analysis of cancer patients with multiple endpoints using global score test methodology." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON MATHEMATICAL SCIENCES. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4882621.

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Zheng, Kangfeng, Xiujuan Wang, Yixian Yang, and Shize Guo. "Applying Multiple Residual Error Gray Forecast to Restrain Endpoints Effect in HHT of Network Traffic." In 2010 First International Conference on Pervasive Computing, Signal Processing and Applications (PCSPA 2010). IEEE, 2010. http://dx.doi.org/10.1109/pcspa.2010.260.

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White, R. J., F. F. Rahaghi, V. Balasubramanian, et al. "Win Ratio Analysis of the FREEDOM-EV Trial - a Hierarchical Approach to Multiple Clinical Endpoints." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3731.

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Cappi, M. "Multiple BeppoSAX observations of IC 4329A to probe the origin of the Compton reflection component in Seyfert 1 galaxies." In X-RAY ASTRONOMY: Stellar Endpoints,AGN, and the Diffuse X-ray Background. AIP, 2001. http://dx.doi.org/10.1063/1.1434683.

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Reports on the topic "Multiple endpoints"

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MRI-Based PDFF of the Liver, Consensus QIBA Profile. Chair Diego Hernando and Houchun (Harry) Hu. Radiological Society of North America (RSNA)/Quantitative Imaging Biomarkers Alliance (QIBA), 2024. https://doi.org/10.1148/qiba/20240619.

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A QIBA Profile is an implementation guide to generate a biomarker with an effective level of performance, mostly by reducing variability and bias in the measurement. The expected performance is expressed as Claims (Section 1.2). To achieve those claims, Actors, both human and equipment, (for example: scanners, data acquisition parameters, data reconstruction software and algorithms, image analysis tools, technologists and radiographers, medical physicists, radiologists) must meet the Checklist Requirements (Section 3) covering Periodic QA, Subject Handling, Image Data Acquisition, Image Data R

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Neodo, Anna, Fiona Augsburger, Jan Waskowski, Joerg C. Schefold, and Thibaud Spinetti. Monocytic HLA-DR expression and clinical outcomes in adult ICU patients with sepsis – a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0119.

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Review question / Objective: The scope of this review was defined using PICOTS framework where 1) population: adult critically ill patients with sepsis or septic shock; 2) index prognostic factor: cell surface protein expression of mHLA-DR in blood; 3) comparative factor: none; 4) outcomes to be predicted: mortality, secondary infections, length of stay, and organ dysfunction score (sequential organ failure assessment [SOFA], multiple organ dysfunction score [MODS], logistic organ dysfunction score [LODS]), composite outcomes where component endpoints consist of at least one of the outcomes st

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