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1

Zou, Ji-Ping, Sha Huang, Yan Peng, et al. "Mesenchymal Stem Cells/Multipotent Mesenchymal Stromal Cells (MSCs)." International Journal of Lower Extremity Wounds 11, no. 4 (2012): 244–53. http://dx.doi.org/10.1177/1534734612463935.

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2

Skoloudik, Lukas, Viktor Chrobok, David Kalfert, Zuzana Koci, and Stanislav Filip. "Multipotent mesenchymal stromal cells in otorhinolaryngology." Medical Hypotheses 82, no. 6 (2014): 769–73. http://dx.doi.org/10.1016/j.mehy.2014.03.022.

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3

Sundin, Mikael, Pádraig DʼArcy, C. Christian Johansson, et al. "Multipotent Mesenchymal Stromal Cells Express FoxP3." Journal of Immunotherapy 34, no. 4 (2011): 336–42. http://dx.doi.org/10.1097/cji.0b013e318217007c.

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4

G??therstr??m, Cecilia. "Immunomodulation by Multipotent Mesenchymal Stromal Cells." Transplantation 84, Supplement (2007): S35—S37. http://dx.doi.org/10.1097/01.tp.0000269200.67707.c8.

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5

Jorgensen, Christian, Farida Djouad, Carine Bouffi, Dominique Mrugala, and Danièle Noël. "Multipotent mesenchymal stromal cells in articular diseases." Best Practice & Research Clinical Rheumatology 22, no. 2 (2008): 269–84. http://dx.doi.org/10.1016/j.berh.2008.01.005.

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6

Tyndall, Alan. "Multipotent Mesenchymal Stromal Cells for Autoimmune Diseases." Transfusion Medicine and Hemotherapy 35, no. 4 (2008): 8. http://dx.doi.org/10.1159/000140859.

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7

Noël, Danièle, Farida Djouad, Carine Bouffi, Dominique Mrugala, and Christian Jorgensen. "Multipotent mesenchymal stromal cells and immune tolerance." Leukemia & Lymphoma 48, no. 7 (2007): 1283–89. http://dx.doi.org/10.1080/10428190701361869.

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8

Husain, Syed R., Yoshikazu Ohya, Junya Toguchida, and Raj K. Puri. "Current Status of Multipotent Mesenchymal Stromal Cells." Tissue Engineering Part B: Reviews 20, no. 3 (2014): 189. http://dx.doi.org/10.1089/ten.teb.2014.0105.

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9

Purdon, Stefanie, Carissa L. Patete, and Marilyn K. Glassberg. "Multipotent Mesenchymal Stromal Cells for Pulmonary Fibrosis?" American Journal of the Medical Sciences 357, no. 5 (2019): 390–93. http://dx.doi.org/10.1016/j.amjms.2019.02.007.

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10

Śmieszek, Agnieszka, Joanna Szydlarska, Aleksandra Mucha, Martyna Chrapiec, and Krzysztof Marycz. "Enhanced cytocompatibility and osteoinductive properties of sol–gel-derived silica/zirconium dioxide coatings by metformin functionalization." Journal of Biomaterials Applications 32, no. 5 (2017): 570–86. http://dx.doi.org/10.1177/0885328217738006.

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The aim of this study was to evaluate the pro-osteogenic properties of sol–gel-derived silica/zirconium dioxide coatings functionalized with 1 mM of metformin. The matrices were applied on 316L stainless steel using dip-coating technique. First of all, physicochemical properties of biomaterials were evaluated. Surface morphology and topography was determined using energy-dispersive X-ray spectroscopy and atomic force microscopy. The chemical composition was evaluated using Fourier transform infrared spectroscopy. Further, wettability and surface free energy were characterized. Cytocompatibilit
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11

Bambuliak, A. V., N. B. Kuzniak, R. R. Dmitrenko, S. V. Tkachik, and V. A. Honcharenko. "Microscopic Investigation of Compatibility of Samples Containing Multipotent Mesenchimal Stromal Cells of Additive Tissue in Experimental Conditions." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 6 (2020): 59–65. http://dx.doi.org/10.26693/jmbs05.06.059.

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The purpose of the study was to investigate the biocompatibility of samples containing multipotent mesenchymal stromal cells of adipose tissue to replace bone defects. Material and methods. The study was conducted at Bukovina State Medical University, Chernivtsi, Ukraine. Adipose tissue samples were obtained from the neck of 60 experimental animals (white Wistar rats). We selected 4 samples for the toxicological experiment, which allowed to establish the direct influence of factors in the contact of implantation material at the cellular level. Sample № 1 - Multipotent mesenchymal stromal cells
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12

Baer, Patrick C. "Adipose-Derived Stromal/Stem Cells." Cells 9, no. 9 (2020): 1997. http://dx.doi.org/10.3390/cells9091997.

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13

Brinchmann, Jan E. "Expanding autologous multipotent mesenchymal bone marrow stromal cells." Journal of the Neurological Sciences 265, no. 1-2 (2008): 127–30. http://dx.doi.org/10.1016/j.jns.2007.05.006.

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14

He, Qiling, Chao Wan, and Gang Li. "Concise Review: Multipotent Mesenchymal Stromal Cells in Blood." STEM CELLS 25, no. 1 (2006): 69–77. http://dx.doi.org/10.1634/stemcells.2006-0335.

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15

Caimi, Paolo F., Jane Reese, Zhenghong Lee, and Hillard M. Lazarus. "Emerging therapeutic approaches for multipotent mesenchymal stromal cells." Current Opinion in Hematology 17, no. 6 (2010): 505–13. http://dx.doi.org/10.1097/moh.0b013e32833e5b18.

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16

Gonelle-Gispert, Carmen, Reto Baertschiger, Philippe Morel, and Leo Bühler. "Do multipotent mesenchymal stromal cells differentiate into hepatocytes?" Current Opinion in Organ Transplantation 12, no. 6 (2007): 668–72. http://dx.doi.org/10.1097/mot.0b013e3282f19f0f.

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17

Tögel, Florian E., and Joseph V. Bonventre. "Multipotent mesenchymal stromal cells protect against kidney injury." Cytotherapy 15, no. 6 (2013): 629–31. http://dx.doi.org/10.1016/j.jcyt.2013.04.005.

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18

Rubtsov, Yu P., Yu G. Suzdaltseva, K. V. Goryunov, N. I. Kalinina, V. Yu Sysoeva, and V. A. Tkachuk. "Regulation of Immunity via Multipotent Mesenchymal Stromal Cells." Acta Naturae 4, no. 1 (2012): 23–31. http://dx.doi.org/10.32607/20758251-2012-4-1-23-31.

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Immune cells responsible for inflammation development are involved in tissue damage caused by wounding and various pathologies. Control of immune cell activation could be of significant benefit for regenerative medicine and the treatment of patients with autoimmune and degenerative diseases. It is a proven fact that MCSs (multipotent mesenchymal stromal cells) are capable of suppressing immune responses via the inhibition of dendritic cell maturation and via the restraining of the T, B, and NK cell function in the course of autoimmune diseases and various forms of inflammation. MSCs can be iso
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19

Bochkov, N. P., E. S. Voronina, N. V. Kosyakova, et al. "Chromosome variability of human multipotent mesenchymal stromal cells." Bulletin of Experimental Biology and Medicine 143, no. 1 (2007): 122–26. http://dx.doi.org/10.1007/s10517-007-0031-0.

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20

Bigildeev, Alexey E., Oxana A. Zhironkina, Irina N. Shipounova, Natalia V. Sats, Svetlana Y. Kotyashova, and Nina I. Drize. "Clonal composition of human multipotent mesenchymal stromal cells." Experimental Hematology 40, no. 10 (2012): 847–56. http://dx.doi.org/10.1016/j.exphem.2012.06.006.

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21

Volkova, N. А. "MULTIPOTENT MESENCHYMAL STROMAL CELLS OF BONE MARROW IN THERAPY OF CHRONIC INFLAMMATION OF THE MURINE OVARIES." Biotechnologia acta 7, no. 5 (2014): 35–42. http://dx.doi.org/10.15407/biotech7.05.035.

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22

Borovkova, N. V., M. Sh Khubutiya, O. N. Rzhevskaya, A. V. Pinchuk, and D. A. Vasil’chenkov. "Multipotent mesenchymal stem cells in renal transplantation." Transplantologiya. The Russian Journal of Transplantation 11, no. 1 (2019): 21–36. http://dx.doi.org/10.23873/2074-0506-2019-11-1-21-36.

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Kidney transplantation is the most effective treatment for the end-stage chronic renal disease that has been observed to increase in the incidence consistently in recent years. Despite the achievements in immunosuppressive therapy in patients after renal transplantation, the graft survival length has remained unchangeable during the recent few decades. Bone marrow multipotent mesenchymal (stromal) stem cells (BM MMSCs) are known as a potential tool to influence this situation. Since their discovery in the middle of the XX century, their wide therapeutic potential in the transplantation of soli
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23

Sukhikh, G. T., A. V. Degtyareva, D. N. Silachev, et al. "Therapeutic effect of human umbilical cord-derived multipotent mesenchymal stromal cells in a patient with Crigler–Najjar syndrome type I." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 64, no. 4 (2019): 26–34. http://dx.doi.org/10.21508/1027-4065-2019-64-4-26-34.

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The article presents the results of intravenous transplantation of allogeneic multipotent mesenchymal stromal cells, derived from a human umbilical cord, to a child with Crigler–Najjarsyndrome type I during the first 2 years of life. The therapy is aimed at reduction of the duration of phototherapy while maintaining a safe level of serum bilirubin.In this study, a five-day-old child with the bilirubin level of 340 µmol/l was treated with phototherapy for 16–18 hours daily in the neonatal period. Then, phototherapy was reduced to 14–16 hours. The level of bilirubin varied from 329 to 407 μmol/l
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24

Megnis, Kaspars, Ilona Mandrika, Ramona Petrovska, et al. "Functional Characteristics of Multipotent Mesenchymal Stromal Cells from Pituitary Adenomas." Stem Cells International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/7103720.

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Pituitary adenomas are one of the most common endocrine and intracranial neoplasms. Although they are theoretically monoclonal in origin, several studies have shown that they contain different multipotent cell types that are thought to play an important role in tumor initiation, maintenance, and recurrence after therapy. In the present study, we isolated and characterized cell populations from seven pituitary somatotroph, nonhormonal, and lactotroph adenomas. The obtained cells showed characteristics of multipotent mesenchymal stromal cells as observed by cell morphology, cell surface marker C
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25

Zuk, Patricia A., Min Zhu, Peter Ashjian, et al. "Human Adipose Tissue Is a Source of Multipotent Stem Cells." Molecular Biology of the Cell 13, no. 12 (2002): 4279–95. http://dx.doi.org/10.1091/mbc.e02-02-0105.

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Much of the work conducted on adult stem cells has focused on mesenchymal stem cells (MSCs) found within the bone marrow stroma. Adipose tissue, like bone marrow, is derived from the embryonic mesenchyme and contains a stroma that is easily isolated. Preliminary studies have recently identified a putative stem cell population within the adipose stromal compartment. This cell population, termed processed lipoaspirate (PLA) cells, can be isolated from human lipoaspirates and, like MSCs, differentiate toward the osteogenic, adipogenic, myogenic, and chondrogenic lineages. To confirm whether adipo
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26

Lakshmipathy, Uma, and Ronald P. Hart. "Concise Review: MicroRNA Expression in Multipotent Mesenchymal Stromal Cells." Stem Cells 26, no. 2 (2008): 356–63. http://dx.doi.org/10.1634/stemcells.2007-0625.

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27

Leuning, Daniëlle G., Marlies E. J. Reinders, Johannes W. de Fijter, and Ton J. Rabelink. "Clinical Translation of Multipotent Mesenchymal Stromal Cells in Transplantation." Seminars in Nephrology 34, no. 4 (2014): 351–64. http://dx.doi.org/10.1016/j.semnephrol.2014.06.002.

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28

Chen, Chie-Pein. "Human placental multipotent mesenchymal stromal cells and placental angiogenesis." Placenta 57 (September 2017): 235–36. http://dx.doi.org/10.1016/j.placenta.2017.07.053.

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29

OKADA, Takashi. "Gene Therapy with Vector-producing Multipotent Mesenchymal Stromal Cells." YAKUGAKU ZASSHI 130, no. 11 (2010): 1513–18. http://dx.doi.org/10.1248/yakushi.130.1513.

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30

Clark, Elizabeth A., Stefanos Kalomoiris, Jan A. Nolta, and Fernando A. Fierro. "Concise Review: MicroRNA Function in Multipotent Mesenchymal Stromal Cells." STEM CELLS 32, no. 5 (2014): 1074–82. http://dx.doi.org/10.1002/stem.1623.

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31

Le Blanc, Katarina, and Dimitrios Mougiakakos. "Multipotent mesenchymal stromal cells and the innate immune system." Nature Reviews Immunology 12, no. 5 (2012): 383–96. http://dx.doi.org/10.1038/nri3209.

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32

Shipunova, N. N., N. A. Petinati, and N. I. Drize. "Effect of Hydrocortisone on Multipotent Human Mesenchymal Stromal Cells." Bulletin of Experimental Biology and Medicine 155, no. 1 (2013): 159–63. http://dx.doi.org/10.1007/s10517-013-2102-8.

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33

Johann, Pascal David, and Ingo Müller. "Multipotent Mesenchymal Stromal Cells: Possible Culprits in Solid Tumors?" Stem Cells International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/914632.

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The clinical use of bone marrow derived multipotent mesenchymal stromal cells (BM-MSCs) in different settings ranging from tissue engineering to immunotherapies has prompted investigations on the properties of these cells in a variety of other tissues. Particularly the role of MSCs in solid tumors has been the subject of many experimental approaches. While a clear phenotypical distinction of tumor associated fibroblasts (TAFs) and MSCs within the tumor microenvironment is still missing, the homing of bone marrow MSCs in tumor sites has been extensively studied. Both, tumor-promoting and tumor-
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34

Sorrentino, Antonio, Manuela Ferracin, Germana Castelli, et al. "Isolation and characterization of CD146+ multipotent mesenchymal stromal cells." Experimental Hematology 36, no. 8 (2008): 1035–46. http://dx.doi.org/10.1016/j.exphem.2008.03.004.

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35

Petrella, Francesco, Isabella Rimoldi, Stefania Rizzo, and Lorenzo Spaggiari. "Mesenchymal Stromal Cells for Antineoplastic Drug Loading and Delivery." Medicines 4, no. 4 (2017): 87. http://dx.doi.org/10.3390/medicines4040087.

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Mesenchymal stromal cells are a population of undifferentiated multipotent adult cells possessing extensive self-renewal properties and the potential to differentiate into a variety of mesenchymal lineage cells. They express broad anti-inflammatory and immunomodulatory activity on the immune system and after transplantation can interact with the surrounding microenvironment, promoting tissue healing and regeneration. For this reason, mesenchymal stromal cells have been widely used in regenerative medicine, both in preclinical and clinical settings. Another clinical application of mesenchymal s
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36

Nadri, Samad, Masoud Soleimani, Jafar Kiani, Amir Atashi, and Reza Izadpanah. "Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells." Differentiation 76, no. 3 (2008): 223–31. http://dx.doi.org/10.1111/j.1432-0436.2007.00216.x.

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37

Vishnubalaji, Radhakrishnan, May Al-Nbaheen, Balamuthu Kadalmani, Abdullah Aldahmash, and Thiyagarajan Ramesh. "Skin-derived multipotent stromal cells – an archrival for mesenchymal stem cells." Cell and Tissue Research 350, no. 1 (2012): 1–12. http://dx.doi.org/10.1007/s00441-012-1471-z.

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38

Reyes, Morayma, Sheng Li, Jessica Foraker, En Kimura, and Jeffrey S. Chamberlain. "Donor origin of multipotent adult progenitor cells in radiation chimeras." Blood 106, no. 10 (2005): 3646–49. http://dx.doi.org/10.1182/blood-2004-12-4603.

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AbstractMultipotent adult progenitor cells (MAPCs) are bone marrow-derived stem cells that have extensive in vitro expansion capacity and can differentiate in vivo and in vitro into tissue cells of all 3 germinal layers: ectoderm, mesoderm, and endoderm. The origin of MAPCs within bone marrow is unknown. MAPCs are believed to be derived from the bone marrow stroma compartment as they are isolated within the adherent cell component. Numerous studies of bone marrow chimeras in the human and the mouse point to a host origin of bone marrow stromal cells. Mesenchymal stem cells (MSCs), which coexis
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39

Chinnici, Cinzia Maria, Giandomenico Amico, Marcello Monti, et al. "Isolation and Characterization of Multipotent Cells from Human Fetal Dermis." Cell Transplantation 23, no. 10 (2014): 1169–85. http://dx.doi.org/10.3727/096368913x668618.

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We report that cells from human fetal dermis, termed here multipotent fetal dermal cells, can be isolated with high efficiency by using a nonenzymatic, cell outgrowth method. The resulting cell population was consistent with the definition of mesenchymal stromal cells by the International Society for Cellular Therapy. As multipotent fetal dermal cells proliferate extensively, with no loss of multilineage differentiation potential up to passage 25, they may be an ideal source for cell therapy to repair damaged tissues and organs. Multipotent fetal dermal cells were not recognized as targets by
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40

Miranda-Sayago, Jose Maria, Nieves Fernández-Arcas, Carmen Benito, Armando Reyes-Engel, Jorge Carrera, and Antonio Alonso. "Lifespan of human amniotic fluid-derived multipotent mesenchymal stromal cells." Cytotherapy 13, no. 5 (2011): 572–81. http://dx.doi.org/10.3109/14653249.2010.547466.

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41

Fernandes, Hugo, Anouk Mentink, Ruud Bank, Reinout Stoop, Clemens van Blitterswijk, and Jan de Boer. "Endogenous Collagen Influences Differentiation of Human Multipotent Mesenchymal Stromal Cells." Tissue Engineering Part A 16, no. 5 (2010): 1693–702. http://dx.doi.org/10.1089/ten.tea.2009.0341.

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42

Bouffi, C., F. Djouad, M. Mathieu, D. Noel, and C. Jorgensen. "Multipotent mesenchymal stromal cells and rheumatoid arthritis: risk or benefit?" Rheumatology 48, no. 10 (2009): 1185–89. http://dx.doi.org/10.1093/rheumatology/kep162.

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43

Andreeva, E. R., and D. K. Matveeva. "Multipotent Mesenchymal Stromal Cells and Extracellular Matrix: Regulation under Hypoxia." Human Physiology 44, no. 6 (2018): 696–705. http://dx.doi.org/10.1134/s0362119718060038.

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44

Rylova, Yu V., N. V. Milovanova, M. N. Gordeeva, and A. M. Savilova. "Characteristics of Multipotent Mesenchymal Stromal Cells from Human Terminal Placenta." Bulletin of Experimental Biology and Medicine 159, no. 2 (2015): 253–57. http://dx.doi.org/10.1007/s10517-015-2935-4.

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45

Savilova, A. M., M. N. Yushina, Y. V. Rudimova, E. G. Khil’kevich, and V. D. Chuprynin. "Characteristics of Multipotent Mesenchymal Stromal Cells Isolated from Human Endometrium." Bulletin of Experimental Biology and Medicine 160, no. 4 (2016): 560–64. http://dx.doi.org/10.1007/s10517-016-3218-4.

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46

Andreeva, Elena, Polina Bobyleva, Aleksandra Gornostaeva, and Ludmila Buravkova. "Interaction of multipotent mesenchymal stromal and immune cells: Bidirectional effects." Cytotherapy 19, no. 10 (2017): 1152–66. http://dx.doi.org/10.1016/j.jcyt.2017.07.001.

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47

Shablii, V., M. Kuchma, H. Svitina, et al. "High Proliferative Placenta-Derived Multipotent Cells Express Cytokeratin 7 at Low Level." BioMed Research International 2019 (July 15, 2019): 1–13. http://dx.doi.org/10.1155/2019/2098749.

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The purpose of this study was to investigate the immunophenotypes and gene expression profile of high proliferative placenta-derived multipotent cells (PDMCs) population at different stages of culture. We demonstrated that the colonies resulting from single cells were either positive or negative for CK7, whereas only PDMC clones with weak CK7 expression (CK7low-clones) were highly proliferative. Interestingly, vimentin positive (Vim+) placental stromal mesenchymal cells did not express CK7 in situ, but double CK7+Vim+ cells detection in tissue explants and explants outgrowth indicated CK7 indu
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48

A. V., Zlatska. "EXPRESSION OF ESTROGEN AND PROGESTERONE RECEPTORS BY HUMAN ENDOMETRIAL MULTIPOTENT MESENCHYMAL STROMAL/STEM CELLS in vitro UNDER HYPOXIA CONDITIONS." Biotechnologia Acta 12, no. 1 (2019): 81–85. http://dx.doi.org/10.15407/biotech12.01.081.

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49

Alishahi, Masoumeh, Amir Anbiyaiee, Maryam Farzaneh, and Seyed E. Khoshnam. "Human Mesenchymal Stem Cells for Spinal Cord Injury." Current Stem Cell Research & Therapy 15, no. 4 (2020): 340–48. http://dx.doi.org/10.2174/1574888x15666200316164051.

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Spinal Cord Injury (SCI), as a devastating and life-altering neurological disorder, is one of the most serious health issues. Currently, the management of acute SCI includes pharmacotherapy and surgical decompression. Both the approaches have been observed to have adverse physiological effects on SCI patients. Therefore, novel therapeutic targets for the management of SCI are urgently required for developing cell-based therapies. Multipotent stem cells, as a novel strategy for the treatment of tissue injury, may provide an effective therapeutic option against many neurological disorders. Mesen
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50

Dominici, Massimo, Paolo Paolucci, Pierfranco Conte, and Edwin M. Horwitz. "Heterogeneity of Multipotent Mesenchymal Stromal Cells: From Stromal Cells to Stem Cells and Vice Versa." Transplantation 87, Supplement (2009): S36—S42. http://dx.doi.org/10.1097/tp.0b013e3181a283ee.

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