Relevant bibliographies by topics / Multisteps organic synthesis

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Multisteps organic synthesis'

Author: Grafiati
Published: 25 January 2025
Last updated: 31 July 2025

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Journal articles on the topic "Multisteps organic synthesis"

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Huang, Jianhui, Caifeng Li, Liu Liu, and Xuegang Fu. "Norbornene in Organic Synthesis." Synthesis 50, no. 15 (2018): 2799–823. http://dx.doi.org/10.1055/s-0037-1610143.

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The norbornene skeleton possesses an alkene functionality with a fixed conformation, and represents unique reactivity. The use of norbornene and analogues as substrates is overviewed; reactivities are discussed as well as the role of norbornenes as ligands assisting modern organic transformations.1 Introduction2 Synthesis of Substituted Norbornenes2.1 Preparation of Functionalized Norbornenes by Deprotonation and Substitution Reactions2.2 Preparation of Functionalized Norbornenes under Palladium-Catalyzed­ Reaction Conditions2.3 Alkylation of Norbornene2.4 Multistep Synthesis3 Synthesis of Sub
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Ren, Yun-Lai, Jianji Wang, Xinzhe Tian, Fangping Ren, Xinqiang Cheng, and Shuang Zhao. "Direct Conversion of Benzyl Ethers into Aryl Nitriles." Synlett 29, no. 18 (2018): 2444–48. http://dx.doi.org/10.1055/s-0037-1611062.

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A direct method was developed for the conversion of benzyl ethers into aryl nitriles by using NH4OAc as the nitrogen source and ­oxygen as the terminal oxidant with catalysis by TEMPO/HNO3; the method is valuable for both the synthesis of aromatic nitriles and for the deprotection of ether-protected hydroxy groups to form nitrile groups in multistep organic syntheses.
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Sakai, Naomi, and Stefan Matile. "Multistep organic synthesis of modular photosystems." Beilstein Journal of Organic Chemistry 8 (June 19, 2012): 897–904. http://dx.doi.org/10.3762/bjoc.8.102.

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Quite extensive synthetic achievements vanish in the online supporting information of publications on functional systems. Underappreciated, their value is recognized by experts only. As an example, we here focus in on the recent synthesis of multicomponent photosystems with antiparallel charge-transfer cascades in co-axial hole- and electron-transporting channels. The synthetic steps are described one-by-one, starting with commercial starting materials and moving on to key intermediates, such as asparagusic acid, an intriguing natural product, as well as diphosphonate “feet”, and panchromatic
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Glaser, John A. "Multistep organic synthesis using flow chemistry." Clean Technologies and Environmental Policy 15, no. 2 (2013): 205–11. http://dx.doi.org/10.1007/s10098-013-0599-1.

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Shukla, Chinmay A., and Amol A. Kulkarni. "Automating multistep flow synthesis: approach and challenges in integrating chemistry, machines and logic." Beilstein Journal of Organic Chemistry 13 (May 19, 2017): 960–87. http://dx.doi.org/10.3762/bjoc.13.97.

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The implementation of automation in the multistep flow synthesis is essential for transforming laboratory-scale chemistry into a reliable industrial process. In this review, we briefly introduce the role of automation based on its application in synthesis viz. auto sampling and inline monitoring, optimization and process control. Subsequently, we have critically reviewed a few multistep flow synthesis and suggested a possible control strategy to be implemented so that it helps to reliably transfer the laboratory-scale synthesis strategy to a pilot scale at its optimum conditions. Due to the va
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Salame, Issa I., Pauline Casino, and Natasha Hodges. "Examining Challenges that Students Face in Learning Organic Chemistry Synthesis." International Journal of Chemistry Education Research 3, no. 3 (2020): 1–9. http://dx.doi.org/10.20885/ijcer.vol4.iss1.art1.

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Organic chemistry is the offered after general chemistry and is the course that many find it challenging and difficult. Synthesis is first introduced in organic chemistry I course and is widely considered as one of the topics in which students struggle with and is evident in their performance in the topic. Our method of data collection is a Likert-type and open-ended questionnaire that was distributed at the end organic chemistry I course in an anonymous fashion. The collected data enabled us to examine the challenges students face in learning organic chemistry synthesis. Our findings support
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Ortega, Pedro, Miguel Guzmán, and Leonel Vera. "Useful Spreadsheet for Updating Multistep Organic Synthesis." Journal of Chemical Education 73, no. 8 (1996): 726. http://dx.doi.org/10.1021/ed073p726.

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Saito, Hayate, Jun Shimokawa, and Hideki Yorimitsu. "The dioxasilepanyl group as a versatile organometallic unit: studies on stability, reactivity, and utility." Chemical Science 12, no. 27 (2021): 9546–55. http://dx.doi.org/10.1039/d1sc02083h.

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Azzena, Ugo, Massimo Carraro, Gloria Modugno, Luisa Pisano, and Luigi Urtis. "Heterogeneous acidic catalysts for the tetrahydropyranylation of alcohols and phenols in green ethereal solvents." Beilstein Journal of Organic Chemistry 14 (July 3, 2018): 1655–59. http://dx.doi.org/10.3762/bjoc.14.141.

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The application of heterogeneous catalysis and green solvents to the set up of widely employed reactions is a challenge in contemporary organic chemistry. We applied such an approach to the synthesis and further conversion of tetrahydropyranyl ethers, an important class of compounds widely employed in multistep syntheses. Several alcohols and phenols were almost quantitatively converted into the corresponding tetrahydropyranyl ethers in cyclopentyl methyl ether or 2-methyltetrahydrofuran employing NH4HSO4 supported on SiO2 as a recyclable acidic catalyst. Easy work up of the reaction mixtures
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Sharma, Mrityunjay K., Roopashri B. Acharya, Chinmay A. Shukla, and Amol A. Kulkarni. "Assessing the possibilities of designing a unified multistep continuous flow synthesis platform." Beilstein Journal of Organic Chemistry 14 (July 26, 2018): 1917–36. http://dx.doi.org/10.3762/bjoc.14.166.

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The multistep flow synthesis of complex molecules has gained momentum over the last few years. A wide range of reaction types and conditions have been integrated seamlessly on a single platform including in-line separation as well as monitoring. Beyond merely getting considered as ‘flow version’ of conventional ‘one-pot synthesis’, multistep flow synthesis has become the next generation tool for creating libraries of new molecules. Here we give a more ‘engineering’ look at the possibility of developing a ‘unified multistep flow synthesis platform’. A detailed analysis of various scenarios is p
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Dissertations / Theses on the topic "Multisteps organic synthesis"

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Michel, Laurane. "Conception et synthèse d'outils chimiques pour observer et comprendre le fonctionnement mitochondrial : vers le développement de nouvelles stratégies thérapeutiques." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF079.

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La mitochondrie est apparue ces dernières années comme une cible thérapeutique d'intérêt. Cet organite des cellules eucaryotes joue un rôle fondamental dans la production énergétique de la cellule. La dérégulation de son fonctionnement est associée à une grande diversité de pathologies telles que des maladies neurodégénératives, métaboliques, cardiovasculaires, cancer et maladies rares mitochondriales. Ainsi, depuis la fin des années 80, différentes stratégies de vectorisation ont été développées, permettant le transport de substances actives à l'intérieur de la mitochondrie. Le nombre grandis
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Sjölin, Olof. "Synthesis of Substituted Pyrrolidines." Thesis, KTH, Skolan för kemivetenskap (CHE), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-207056.

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The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties.  This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance. In this work, a synthetic pathway from cheapand readily available starting materials to highly modifiable 2,4-disubstitutedpyrrolidines is demonstrated. Previously reported procedures to similarpyrrolidines use expensive catalysts, requires harsh
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Saito, Hayate. "Development of Silyl Groups Bearing Bulky Alkoxy Unit and Their Application to Organic Synthesis." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263488.

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Riva, E. "FLOW CHEMISTRY APPLIED TO THE PREPARATION OF SMALL MOLECULES POTENTIALLY USEFUL AS THERAPEUTIC AGENTS." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/155261.

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In recent years, despite the large amount of novel and clinically validated targets identified from the human genome project, the number of new drug launched on the market is decreasing and the overall costs for the development of a drug are rising significantly. Pharmaceutical and biotechnology companies are under a strong pressure to produce a steady stream of innovative, well-differentiated drugs with a reduced cost both for discovery and development. Currently it takes an estimated 10-14 years to develop and market a drug at a cost that exceeds 1 billion dollars. With the aim at increasin
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Books on the topic "Multisteps organic synthesis"

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Mayo, Dana W. Microscale organic laboratory: With multistep and multiscale syntheses. 5th ed. J. Wiley & Sons, 2011.

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M, Pike Ronald, and Trumper Peter K. 1955-, eds. Microscale organic laboratory: With multistep and multiscale syntheses. 4th ed. Wiley, 2000.

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Mayo, Dana W. Microscale organic laboratory: With multistep and multiscale syntheses. 3rd ed. Wiley, 1994.

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Mayo, Dana W. Microscale organic laboratory: With multistep and multiscale syntheses. 5th ed. J. Wiley & Sons, 2011.

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Microscale Organic Laboratory: With Multistep and Multiscale Syntheses. Wiley & Sons, Incorporated, John, 2022.

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Microscale Organic Laboratory: With Multistep and Multiscale Syntheses. Wiley & Sons, Incorporated, John, 2023.

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Mayo, Dana W., Ronald M. Pike, and David C. Forbes. Microscale Organic Laboratory: With Multistep and Multiscale Syntheses. Wiley & Sons, Incorporated, John, 2013.

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Mayo, Dana W., Ronald M. Pike, and David C. Forbes. Microscale Organic Laboratory with Multistep and Multiscale Syntheses. Wiley & Sons, Incorporated, John, 2010.

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Microscale Organic Laboratory with Multistep and Multiscale Syntheses, Binder Ready Version. Wiley, 2013.

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Mayo, Dana W., Ronald M. Pike, and David C. Forbes. Microscale Organic Laboratory with Multistep and Multiscale Syntheses, 7th Edition Binder Ready Version. Wiley & Sons, Limited, John, 2023.

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Book chapters on the topic "Multisteps organic synthesis"

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Carey, Francis A., and Richard J. Sundberg. "Multistep Syntheses." In Advanced Organic Chemistry. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-9797-7_13.

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Panunzio, Mauro, Maria Antonietta Lentini, Eileen Campana, Giorgio Martelli, and Paola Vicennati. "Multistep Microwave-Assisted Solvent-Free Organic Reactions: Synthesis of 1,6-Disubstituted-4-Oxo-1,4-Dihydro-Pyridine-3-Carboxylic Acid Benzyl Esters." In Advances in Microwave and Radio Frequency Processing. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/978-3-540-32944-2_41.

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"Carbonyl Chemistry in a Multistep Synthesis." In Advanced Organic Synthesis. CRC Press, 2015. http://dx.doi.org/10.1201/b19502-14.

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"Multistep Synthesis of a Bioactive Peptidomimetic." In Advanced Organic Synthesis. CRC Press, 2015. http://dx.doi.org/10.1201/b19502-15.

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Lam, K., M. C. Leech, and A. J. J. Lennox. "14 Electrochemistry in Natural Product Synthesis." In Electrochemistry in Organic Synthesis. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/sos-sd-236-00280.

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The multistep synthesis of natural products has historically served as a useful and informative platform for showcasing the best, state-of-the-art synthetic methodologies and technologies. Over the last several decades, electrochemistry has proved itself to be a useful tool for conducting redox reactions. This is primarily due to its unique ability to selectively apply any oxidizing or reducing potential to a sufficiently conductive reaction solution. Electrochemical redox reactions are readily scaled and can be more sustainable than competing strategies based on conventional redox reagents. I
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Doraiswamy, L. K. "Complex Reactions." In Organic Synthesis Engineering. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195096897.003.0010.

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When a reactant or a set of reactants undergoes several reactions (at least two) simultaneously, the reaction is said to be a complex reaction. The total conversion of the key reactant, which is used as a measure of reaction in simple reactions, has little meaning in complex reactions, and what is of primary interest is the fraction of reactant converted to the desired product. Thus the more pertinent quantity is product distribution from which the conversion to the desired product can be calculated. This is usually expressed in terms of the yield or selectivity of the reaction with respect to
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"9 Immobilized Reagents and Multistep Processes." In Flow Chemistry in Organic Synthesis, edited by Jamison and Koch. Georg Thieme Verlag, 2018. http://dx.doi.org/10.1055/sos-sd-228-00177.

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O’Brien, A. G. "15.1 Flow Chemistry in the Pharmaceutical Industry: Part 1." In Flow Chemistry in Organic Synthesis. Georg Thieme Verlag, 2018. http://dx.doi.org/10.1055/sos-sd-228-00248.

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Abstract The use of flow chemistry in the single- and multistep synthesis of active pharmaceutical ingredients has been well demonstrated. The pharmaceutical industry is now taking the next steps towards integration of flow chemistry into large-scale commercialized processes, which can effectively supply patient populations. This chapter details advances in this area, and outlines the data and knowledge required to select, develop, scale, and commercialize an efficient flow process.
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Bhatt, Priyanka, and Manoj Kumar. "Multicomponent Reaction in Ionic Liquid for Ecocompatible Heterocyclic Synthesis." In Ionic Liquids for Organic Synthesis. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815313413125010008.

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Multicomponent reactions (MCRs) provide a unique way to incorporate the structural attributes of three or more reactants in a single operation. Along with their operational simplicity and synthetic convergence, MCRs are generally atom, step, and time economical than comparable multistep processes. On the other hand, ionic liquids (ILs) are salts with low melting points. Because of their low vapor pressure, recyclability, and tunability, ILs offer a task-specific alternative to commonly employed organic solvents. Thus, merging both strategies (MCRs & ILs) together opens the way to a plethor
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Castilho, Paula C., and Pedro Ideia. "14.3. Multistep Synthesis of Dilantin." In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom. The Royal Society of Chemistry, 2016. http://dx.doi.org/10.1039/9781849739634-00821.

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