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1

Schoenau, Eckhard, Christina Maria Neu, Bodo Beck, Friedrich Manz, and Frank Rauch. "Bone Mineral Content per Muscle Cross-Sectional Area as an Index of the Functional Muscle-Bone Unit." Journal of Bone and Mineral Research 17, no. 6 (2002): 1095–101. http://dx.doi.org/10.1359/jbmr.2002.17.6.1095.

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2

Chiu, Tai-Hua, Szu-Chia Chen, Hui-Chen Yu, et al. "Association between Geriatric Nutrition Risk Index and Skeletal Muscle Mass Index with Bone Mineral Density in Post-Menopausal Women Who Have Undergone Total Thyroidectomy." Nutrients 12, no. 6 (2020): 1683. http://dx.doi.org/10.3390/nu12061683.

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Background: Osteoporosis is highly prevalent in postmenopausal women and may result in fractures and disabilities. Total thyroidectomy has also been associated with loss of bone mass. The aim of this cross-sectional study was to evaluate associations among nutritional status, skeletal muscle index and markers of bone turnover to bone mineral density in postmenopausal women who had undergone total thyroidectomy. Methods: Fifty postmenopausal women who had undergone total thyroidectomy were included. Body composition was measured using dual-energy X-ray absorptiometry (DXA). The Geriatric Nutrit
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Sekiya, Ichiro, Takeshi Muneta, Takashi Ogiuchi, Kazuyoshi Yagishita, and Haruyasu Yamamoto. "Significance of the Single-Legged Hop Test to the Anterior Cruciate Ligament-Reconstructed Knee in Relation to Muscle Strength and Anterior Laxity." American Journal of Sports Medicine 26, no. 3 (1998): 384–88. http://dx.doi.org/10.1177/03635465980260030701.

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We investigated the significance of the single-legged hop test to the anterior cruciate ligament-reconstructed knee as it specifically relates to knee muscle strength recovery and residual anterior laxity. The hop test was conducted on 107 patients with unilateral anterior cruciate ligament-reconstructed knees (78 semitendinosus tendon autografts and 29 bone-patellar tendon-bone autografts). Patients were tested an average of 2 years after surgery. Correlation coefficient analyses determined whether the relationship between knee muscle strength recovery and the hop test was invariant across al
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Lin, Yu-Ching, Yu-Hsiang Juan, Wing P. Chan, et al. "Integrating Muscle Health in Predicting the Risk of Asymptomatic Vertebral Fracture in Older Adults." Journal of Clinical Medicine 10, no. 5 (2021): 1129. http://dx.doi.org/10.3390/jcm10051129.

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Background: The utility of muscle health for predicting asymptomatic vertebral fracture (VF) is uncertain. We aimed to determine the effects of muscle health on bone quantity and quality in the older adults and to integrate these factors into a predictive model for VF. Methods: We prospectively recruited participants with a body mass index <37 kg/m2. The total lean mass (TLM), appendicular skeletal muscle index, presence of sarcopenia, and bone mineral density were determined by dual-energy X-ray absorptiometry, and bone quality by the trabecular bone score (TBS). VF was diagnosed based on
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Nonaka, Koji, Shin Murata, Hideki Nakano, et al. "Association of Low Bone Mass with Decreased Skeletal Muscle Mass: A Cross-Sectional Study of Community-Dwelling Older Women." Healthcare 8, no. 3 (2020): 343. http://dx.doi.org/10.3390/healthcare8030343.

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This study aimed to investigate the characteristics of skeletal muscle mass, muscle strength, and physical performance among community-dwelling older women. Data were collected from 306 older adults, and the data of 214 older women were included in the final analysis. Participants’ calcaneus bone mass was measured using ultrasonography. Based on their T-scores, participants were divided into the following three groups: normal (T-score > −1), low (−2.5 < T-score ≤ −1), and very low (T-score ≤ −2.5) bone mass. Further, participants’ skeletal muscle mass, muscle strength (grip and knee exte
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Abshire, Demetrius A., Debra K. Moser, Jody L. Clasey, et al. "Body Composition and Bone Mineral Density in Patients With Heart Failure." Western Journal of Nursing Research 39, no. 4 (2016): 582–99. http://dx.doi.org/10.1177/0193945916658885.

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The purpose of this study was to examine associations among bone mineral density, osteopenia/osteoporosis, body mass index (BMI), and body composition in patients with heart failure (HF). A total of 119 patients (age = 61 ± 12 years, 65% male) underwent dual-energy X-ray absorptiometry scans to determine bone mineral density and body composition. In multivariable linear regressions, BMI, relative skeletal muscle index (RSMI), and mineral-free lean mass were positively associated with total body bone mineral density. Mineral-free lean mass was most strongly associated with bone mineral density
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7

Ludwa, Izabella A., Kevin Mongeon, Malcolm Sanderson, Luis Gracia Marco, and Panagiota Klentrou. "Testing the Functional Model of Bone Development: Direct and Mediating Role of Muscle Strength on Bone Properties in Growing Youth." International Journal of Environmental Research and Public Health 18, no. 6 (2021): 3154. http://dx.doi.org/10.3390/ijerph18063154.

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This study examines the functional model of bone development in peri-pubertal boys and girls. Specifically, we implemented a mixed-longitudinal design and hierarchical structural models to provide experimental evidence in support of the conceptual functional model of bone development, postulating that the primary mechanical stimulus of bone strength development is muscle force. To this end, we measured radial and tibial bone properties (speed of sound, SOS), isometric grip and knee extensors strength, bone resorption (urinary NTX concentration), body mass index (BMI), somatic maturity (years f
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8

Grigoreva, I., T. Raskina, J. Averkieva, et al. "SAT0481 RELATIONSHIP BETWEEN SARCOPENIA AND BONE MINERAL DENSITY IN MEN WITH CORONARY HEART DISEASE." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1197.2–1197. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5738.

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Objectives:To study the relationship of indicators of muscle mass, muscle strength and muscle function with bone mineral density (BMD) in men with coronary heart disease (CHD).Methods:79 men aged over 50 years with verified CHD were examined (mean age 63 (57; 66) years).The BMD (g/cm2) and T-criterion (standard deviation) of the femoral neck and lumbar spine (L1-L4) were evaluated using dual-energy x-ray absorptiometry (DXA) on the lunar Prodigy Primo bone densitometer (USA).To assess muscle mass, the total area (cm2) of the lumbar muscles of the axial section at the level of the 3rd lumbar ve
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9

Ehehalt, S., G. Binder, N. Schurr, C. Pfaff, M. B. Ranke, and R. Schweizer. "The Functional Muscle-Bone Unit in Obese Children – Altered Bone Structure Leads to Normal Strength Strain Index." Experimental and Clinical Endocrinology & Diabetes 119, no. 06 (2011): 321–26. http://dx.doi.org/10.1055/s-0031-1277139.

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10

Navajas, E. A., A. J. L. Charteris, K. A. McLean, et al. "Association among objective in vivo and post-slaughter assessments of muscularity in lambs." Proceedings of the British Society of Animal Science 2005 (2005): 44. http://dx.doi.org/10.1017/s1752756200009558.

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Muscularity of lamb carcasses, which is defined as the depth of muscle relative to dimensions of the skeleton (De Boer et al., 1974), is a commercially important trait in many countries. An objective index of muscularity was defined by Purchas et al. (1991) based on the weights of the muscles around a bone and the bone length. Jones et al. (2002) proposed an objective index to assess in vivo the shape of the muscle in the hind leg using X-ray Computed Tomography (CT), which had a phenotypic correlation of 0.63 with dissection measures of muscularity, as described by Purchas et al. (1991).
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11

Lorbergs, Amanda L., Jonathan P. Farthing, Adam D. G. Baxter-Jones, and Saija A. Kontulainen. "Forearm muscle size, strength, force, and power in relation to pQCT-derived bone strength at the radius in adults." Applied Physiology, Nutrition, and Metabolism 36, no. 5 (2011): 618–25. http://dx.doi.org/10.1139/h11-065.

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We aimed to examine the relationship between forearm muscle cross-sectional area (MCSA), muscle force, or rate of torque development (RTD) and 2 estimated radius bone strength indices — compressive bone strength index (BSI) at the wrist and strength strain index in torsion (SSIp) at the shaft — in healthy middle-aged males and females. Distal (4%) and shaft (65%) sites of nondominant forearms were scanned using peripheral quantitative computed tomography (pQCT) in a sample of 48 adults (mean age ± SD, 49.4 ± 2.4 y) to obtain estimated bone strength indices and MCSA. Muscle force, measured by g
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12

Baker, Joshua F., Jin Long, Sogol Mostoufi-Moab, et al. "Muscle Deficits in Rheumatoid Arthritis Contribute to Inferior Cortical Bone Structure and Trabecular Bone Mineral Density." Journal of Rheumatology 44, no. 12 (2017): 1777–85. http://dx.doi.org/10.3899/jrheum.170513.

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Objective.Rheumatoid arthritis (RA) is associated with muscle loss, osteoporosis, and fracture. We examined associations between skeletal muscle mass, strength, and quality and trabecular and cortical bone deficits in patients with RA and healthy controls.Methods.Participants, ages 18–75 years, completed whole-body dual-energy x-ray absorptiometry and peripheral quantitative computed tomography (pQCT) of the tibia to quantify appendicular lean mass and fat mass indices (ALMI, FMI), muscle density at the lower leg, trabecular bone density, and cortical bone thickness. Age-, sex-, and race-speci
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13

Clasey, Jody L., and T. Brock Symons. "Relative Skeletal Muscle Index Correlates with Bone Density and Strength in Young Women." Medicine & Science in Sports & Exercise 43, Suppl 1 (2011): 250. http://dx.doi.org/10.1249/01.mss.0000400685.54220.a0.

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14

Olstad, Ole Kristoffer, Vigdis Teig Gautvik, Marissa LeBlanc, et al. "Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study." Therapeutic Advances in Musculoskeletal Disease 12 (January 2020): 1759720X2092944. http://dx.doi.org/10.1177/1759720x20929443.

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Background: Clinical evidence suggests that body muscle mass is positively associated with bone mass, of significance for the elderly population at risk of osteoporosis (OP). Furthermore, muscle and bone interact mechanically and functionally, via local interactions as well as remotely via secreted components. Thus, it was of interest to compare muscle transcriptomes in postmenopausal OP and healthy women, and study effects of strength training on the muscle transcriptome, muscle stress proteins and bone mineral density (BMD). Methods: Skeletal muscle histological and genetic properties were c
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15

Abidin, Nurdiana Z., and Soma R. Mitra. "Total vs. Bioavailable: Determining a Better 25(OH)D Index in Association with Bone Density and Muscle Mass in Postmenopausal Women." Metabolites 11, no. 1 (2020): 23. http://dx.doi.org/10.3390/metabo11010023.

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The concurrent presence of low bone density (osteopenia/osteoporosis) and low muscle mass (sarcopenia) in older adults has led to the recognition of “osteosarcopenia” (OS) as a singular entity. Vitamin D may play important role in the manifestation of OS, in terms of intake, absorption, and bioavailability. Evidence suggests that bioavailable 25(OH)D may be a better indicator of Vitamin D compared to total 25(OH)D due to its weak bind to albumin, increasing its ‘availability’. The aim of this study was to assess total and bioavailable 25(OH)D levels in postmenopausal women and to determine the
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16

Karguppikar, Madhura Bharat, Veena Ekbote, Anuradha Khadilkar, and Vaman Khadilkar. "Comprehensive evaluation of bone health using DXA and pQCT in an Indian boy with osteogenesis imperfecta." BMJ Case Reports 13, no. 12 (2020): e236169. http://dx.doi.org/10.1136/bcr-2020-236169.

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We present a 9-year-old male child having history of fractures on trivial trauma with a family history of the same. He was treated for osteogenesis imperfecta (OI; zolendronate, calcium and vitamin D) and showed clinical improvement. On evaluating his bone health using dual energy X-ray absorptiometry and peripheral quantitative CT, we found that the child had bone density within the reference range but a smaller bone mass for his height, low muscle mass and thin bones with a lower strength strain index in comparison with healthy children. Our case suggests that treatment with bisphosphonates
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17

Hartard, M., H. Schiessl, P. Bartenstein, Th Hilberg, and D. Jeschke. "CORRELATIONS BETWEEN MAXIMAL MUSCLE-FORCE/-TORQUE AND A BONE STRENGTH INDEX IN UPPER LIMBS." Medicine & Science in Sports & Exercise 30, Supplement (1998): 290. http://dx.doi.org/10.1097/00005768-199805001-01652.

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18

Lim, J., and H. S. Park. "Relationship between underweight, bone mineral density and skeletal muscle index in premenopausal Korean women." International Journal of Clinical Practice 70, no. 6 (2016): 462–68. http://dx.doi.org/10.1111/ijcp.12801.

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19

Aguirre, Lina E., Georgia Colleluori, Richard Dorin, et al. "Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density." Calcified Tissue International 101, no. 6 (2017): 602–11. http://dx.doi.org/10.1007/s00223-017-0316-x.

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20

Wu, Ching-Te, Jiuan-Miaw Liao, Jiunn-Liang Ko, et al. "D-Methionine Ameliorates Cisplatin-Induced Muscle Atrophy via Inhibition of Muscle Degradation Pathway." Integrative Cancer Therapies 18 (January 2019): 153473541982883. http://dx.doi.org/10.1177/1534735419828832.

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Cisplatin induces anorexia, weight loss, loss of adipose tissue, skeletal muscle atrophy, and serious adverse effects that can cause premature termination of chemotherapy. The aim of this study was to use an animal model to assess cisplatin therapy (3 cycles) with and without d-methionine to investigate its protective effects on cisplatin-induced anorexia and skeletal muscle wasting. Wistar rats were divided into 3 groups and treated as follows: saline as control (group 1), intraperitoneal cisplatin once a week for 3 weeks (group 2), and intraperitoneal cisplatin once a week for 3 weeks plus o
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Toroptsova, N. V., O. V. Dobrovolskaya, O. A. Nikitinskaya, A. O. Efremova, A. Yu Feklistov, and N. V. Demin. "Body composition and bone mineral density in postmenopausal women with rheumatoid arthritis." Rheumatology Science and Practice 59, no. 3 (2021): 282–87. http://dx.doi.org/10.47360/1995-4484-2021-282-287.

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Aim – to study the relationship between body composition and bone mineral density (BMD) in postmenopausal women with rheumatoid arthritis (RA).Material and methods. 68 postmenopausal women, median age 59 [54; 63] years, with RA were included in the study. Bone mineral density (BMD) and body composition were assessed with dual energy X-ray absorptiometry.Results. 33 (48.5%) women had osteopenia, and 17 (25.0%) – osteoporosis (OP). Low lean muscle mass was found in 10 (14.7%) patients. There were positive correlations between different areal BMD and body weight, trunk fat, trunk lean muscle mass
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Henriquez, Soledad, Bertrand Dunogué, Raphael Porcher, et al. "Handgrip strength is a comorbidity marker in systemic necrotizing vasculitides and predicts the risk of fracture and serious adverse events." Rheumatology 59, no. 9 (2020): 2581–90. http://dx.doi.org/10.1093/rheumatology/kez680.

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Abstract Objective Sarcopenia has been associated with poor outcomes in various medical and surgical conditions. However, its impact in systemic necrotizing vasculitides (SNV) had never been characterized. We aimed to assess the prevalence, associated factors and prognostic impact of sarcopenia in SNV. Methods Patients with SNV were successively included in a prospective longitudinal study assessing comorbidities. At inclusion, we evaluated sarcopenia by assessing skeletal muscle mass index using DXA and muscle strength using handgrip strength. Vasculitis and treatments-related events were rec
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23

Zellers, Jennifer A., Michael J. Mueller, Paul K. Commean, Ling Chen, Hyo-Jung Jeong, and Mary K. Hastings. "Multi-System Factors Associated with Metatarsophalangeal Joint Deformity in Individuals with Type 2 Diabetes." Journal of Clinical Medicine 9, no. 4 (2020): 1012. http://dx.doi.org/10.3390/jcm9041012.

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The underlying factors contributing to metatarsophalangeal joint deformity, a known precursor to skin breakdown in individuals with diabetes mellitus (DM), is likely to involve multiple body systems. The purpose of this cross-sectional study was to identify multi-system factors associated with metatarsophalangeal joint deformity in individuals with type 2 DM and peripheral neuropathy (n = 60). Metatarsophalangeal joint deformity was quantified with a computed tomography (CT) scan. System biomarkers included the musculoskeletal system (foot intrinsic muscle deterioration, tarsal/metatarsal bone
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Tournis, S., E. Michopoulou, I. G. Fatouros, et al. "Effect of Rhythmic Gymnastics on Volumetric Bone Mineral Density and Bone Geometry in Premenarcheal Female Athletes and Controls." Journal of Clinical Endocrinology & Metabolism 95, no. 6 (2010): 2755–62. http://dx.doi.org/10.1210/jc.2009-2382.

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Abstract Context and Objective: Weight-bearing exercise during growth exerts positive effects on the skeleton. Our objective was to test the hypothesis that long-term elite rhythmic gymnastics exerts positive effects on volumetric bone mineral density and geometry and to determine whether exercise-induced bone adaptation is associated with increased periosteal bone formation or medullary contraction using tibial peripheral quantitative computed tomography and bone turnover markers. Design and Setting: We conducted a cross-sectional study at a tertiary center. Subjects: We studied 26 elite prem
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Mosti, M. P., A. K. Stunes, M. Ericsson та ін. "Effects of the Peroxisome Proliferator-Activated Receptor (PPAR)-δ Agonist GW501516 on Bone and Muscle in Ovariectomized Rats". Endocrinology 155, № 6 (2014): 2178–89. http://dx.doi.org/10.1210/en.2013-1166.

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Estrogen deficiency promotes bone loss and skeletal muscle dysfunction. Peroxisome proliferator-activated receptors (PPARs) have 3 subtypes (α, δ, and γ). PPARγ agonists induce bone loss, whereas PPARα agonists increase bone mass. Although PPARδ agonists are known to influence skeletal muscle metabolism, the skeletal effects are unsettled. This study investigated the musculoskeletal effects of the PPARδ agonist GW501516 in ovariectomized (OVX) rats. Female Sprague Dawley rats, 12 weeks of age, were allocated to a sham-operated group and 3 OVX groups; high-dose GW501516 (OVX-GW5), low-dose GW50
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26

Duran, Ibrahim, Kyriakos Martakis, Christina Stark, Leonie Schafmeyer, Mirko Rehberg, and Eckhard Schoenau. "Effect of an interval rehabilitation program with home-based, vibration-assisted training on the development of muscle and bone in children with cerebral palsy – an observational study." Journal of Pediatric Endocrinology and Metabolism 33, no. 8 (2020): 1083–92. http://dx.doi.org/10.1515/jpem-2020-0080.

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AbstractObjectivesIn children with cerebral palsy (CP), the most common cause of physical impairment in childhood, less muscle and bone growth has been reported, when compared with typically developing children. The aim of this study was to evaluate the effect of an intensive rehabilitation program including physiotherapy in combination with 6 months of home-based, vibration-assisted training on muscle and bone growth in children with CP.MethodsWe included children with CP, who participated in a rehabilitation program utilizing whole-body vibration (WBV). Muscle mass was quantified by appendic
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27

Rice, Paige E., Herman van Werkhoven, Edward K. Merritt, and Jeffrey M. McBride. "Lower Leg Morphology and Stretch-Shortening Cycle Performance of Dancers." Journal of Applied Biomechanics 34, no. 3 (2018): 211–19. http://dx.doi.org/10.1123/jab.2017-0206.

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Greater levels of bone ultimate fracture load, bone stress–strain index, muscle cross-sectional area, and maximal voluntary isometric plantarflexion (MVIP) strength of the lower leg may be adaptations from chronic exposure to stretch-shortening cycle (SSC) actions. Dancers, a population that habitually performs SSC movements primarily about the ankle joint, may serve as a novel population to gain broader understanding of SSC function. A total of 10 female collegiate dancers and 10 untrained controls underwent peripheral quantitative computed tomography scans of both lower legs and performed MV
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Pivtorak, K. V. "Component composition of body weight in patients with non-alcoholic fatty liver disease." Biomedical and Biosocial Anthropology, no. 35 (May 5, 2019): 5–10. http://dx.doi.org/10.31393/bba35-2019-01.

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The issue of the relationship between the features of the component composition of body weight with the emergence and development of non-alcoholic fatty liver disease (NAFLD) is particularly relevant. The purpose of the study is to determine the features of the component composition of the body weight in patients with NAFLD compared with almost healthy people of the first mature age. A comprehensive examination and analysis of anthropometric data of 112 patients with NAFLD of the first mature age of the Podolski region was carried out in comparison with the anthropometric data of practically h
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29

Pang, Marco Y. C., Feigo Z. H. Yang, and Alice Y. M. Jones. "Vascular Elasticity and Grip Strength Are Associated With Bone Health of the Hemiparetic Radius in People With Chronic Stroke: Implications for Rehabilitation." Physical Therapy 93, no. 6 (2013): 774–85. http://dx.doi.org/10.2522/ptj.20120378.

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Background People with stroke often have increased bone loss and fracture rate. Increasing evidence has demonstrated a link between cardiovascular health and bone loss in other patient populations. Objective The study objectives were: (1) to compare the bone density and geometry of the radius diaphysis on the left and right sides in people with chronic stroke and people who were matched for age (control participants) and (2) to examine the relationship between the bone strength index at the hemiparetic radius diaphysis and vascular health in people with chronic stroke. Design This was a case-c
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Pimenta, Luciana Duarte, Danilo Alexandre Massini, Daniel dos Santos, et al. "BONE HEALTH, MUSCLE STRENGTH AND LEAN MASS: RELATIONSHIPS AND EXERCISE RECOMMENDATIONS." Revista Brasileira de Medicina do Esporte 25, no. 3 (2019): 245–51. http://dx.doi.org/10.1590/1517-869220192503210258.

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ABSTRACT Although muscle strength, lean mass and bone mineral content/density (BMC/BMD) are consistently reported as major outcomes of resistance training (RT), there is still no agreement on the RT regimen that is capable of achieving this result in men and women of different ages. This study describes the effects of RT on muscle strength, lean mass and bone mineralization, highlighting the relationships between them and analyzing the effectiveness of the RT protocol. Information searches were conducted in open access online academic libraries, using the BMC/BMD indices combined with muscle s
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Felix, Manny, Jeff McCubbin, and Janet Shaw. "Bone Mineral Density, Body Composition, and Muscle Strength in Premenopausal Women with Mental Retardation." Adapted Physical Activity Quarterly 15, no. 4 (1998): 345–56. http://dx.doi.org/10.1123/apaq.15.4.345.

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Many women with mild to moderate mental retardation (MMR) exhibit low levels of physical activity, muscle strength, and muscle mass, which place these individuals at risk for osteoporosis. Bone mineral density (BMD), the primary index of osteoporosis, of the femoral neck and the whole body was measured in premenopausal women with (M age = 28.14 ± 8.43) and without (M age = 29.64 ± 10.86) mental retardation (MMR and NMR, respectively). Multivariate analyses revealed no differences (p > .05) between groups (MMR = 16, NMR = 16) for BMD values. Significant differences existed (p < .05) betwe
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Han, ChangSook, HyoKyung Kim, and Suhee Kim. "Effects of Adolescents’ Lifestyle Habits and Body Composition on Bone Mineral Density." International Journal of Environmental Research and Public Health 18, no. 11 (2021): 6170. http://dx.doi.org/10.3390/ijerph18116170.

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The incidence of osteoporosis is increasing as the population ages, as is the need to manage and prevent it. Adolescence is the period when the fastest development of bone mass takes place. Increasing adolescents’ maximum bone mass and avoiding the risk factors for its loss are effective for preventing osteoporosis. This study investigated the factors influencing adolescents’ bone mineral density (BMD). The participants were 126 middle- and high-school students from Gangwon-do; 47.6% (n = 60) were male, with an average age of 15 (range 12–18) years of age. It was found that age, carbonated bev
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Libuda, Lars, Stefan A. Wudy, Eckhard Schoenau, and Thomas Remer. "Comparison of the effects of dietary protein, androstenediol and forearm muscle area on radial bone variables in healthy prepubertal children." British Journal of Nutrition 105, no. 3 (2010): 428–35. http://dx.doi.org/10.1017/s0007114510003508.

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Adequate dietary habits are supposed to be one of the most important modifiable factors in osteoporosis prevention. However, the importance of specific nutrients is controversial. We examined relevant nutrients which are supposed to have an impact on bone parameters and compared their effect sizes with those of two known predictors of bone development: bone-related muscle mass and androgen levels. We analysed nutritional, hormonal and anthropometric data from 107 prepubertal children participating in the Dortmund Nutritional and Anthropometric Longitudinally Designed Study. Diaphyseal bone min
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Holm, Lars, Jens L. Olesen, Keitaro Matsumoto, et al. "Protein-containing nutrient supplementation following strength training enhances the effect on muscle mass, strength, and bone formation in postmenopausal women." Journal of Applied Physiology 105, no. 1 (2008): 274–81. http://dx.doi.org/10.1152/japplphysiol.00935.2007.

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We evaluated the response of various muscle and bone adaptation parameters with 24 wk of strength training in healthy, early postmenopausal women when a nutrient supplement (protein, carbohydrate, calcium, and vitamin D) or a placebo supplement (a minimum of energy) was ingested immediately following each training session. At inclusion, each woman was randomly and double-blindedly assigned to a nutrient group or a placebo (control) group. Muscle hypertrophy was evaluated from biopsies, MRI, and dual-energy X-ray absorptiometry (DEXA) scans, and muscle strength was determined in a dynamometer.
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Ohta, Takahisa, Junzo Nagashima, Haruhito Aoki, et al. "Muscle Strength and Bone Strength Assessed with Osteo-sono Assessment Index Among Recreationally Athletic Japanese Women." Medicine & Science in Sports & Exercise 51, Supplement (2019): 218. http://dx.doi.org/10.1249/01.mss.0000561162.15274.bc.

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TOURNIS, SYMEON, VASILIOS SAMDANIS, SAVAS PSARELIS, et al. "Effect of Rheumatoid Arthritis on Volumetric Bone Mineral Density and Bone Geometry, Assessed by Peripheral Quantitative Computed Tomography in Postmenopausal Women Treated with Bisphosphonates." Journal of Rheumatology 39, no. 6 (2012): 1215–20. http://dx.doi.org/10.3899/jrheum.110579.

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Objective.To investigate the effect of rheumatoid arthritis (RA) on volumetric bone mineral density (vBMD) and bone geometry in postmenopausal women treated with bisphosphonates.Methods.Fifty-three postmenopausal women with RA and 87 control subjects, comparable in terms of age, body mass index, and years since menopause, underwent peripheral quantitative computed tomography (pQCT) of the nondominant tibia.Results.At 4% (trabecular site), trabecular bone mineral content (BMC) and vBMD (p < 0.001) were lower in the RA group, while trabecular area was comparable. At 38% (cortical site), corti
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Shah, M., H. Zaneb, S. Masood, et al. "Effect of single or combined supplementation of zinc and probiotics on muscle and bone characteristics and haematobiochemical profile in broilers." Veterinární Medicína 65, No. 3 (2020): 134–42. http://dx.doi.org/10.17221/152/2019-vetmed.

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The study was conducted to elucidate the effect of a single or combined supplementation of zinc sulphate monohydrate (ZnSO<sub>4</sub>.H<sub>2</sub>O) and a probiotic (Protexin<sup>®</sup>) on the pectoral muscle, tibial bone and serum biochemistry in broilers. Day-old chicks (n = 192) were divided into: Control (basal diet), Zn30 (basal diet + ZnSO<sub>4</sub>.H<sub>2</sub>O 30 mg/kg feed), Zn60 (basal diet + ZnSO<sub>4</sub>.H<sub>2</sub>O 60 mg/kg feed), Pro (basal diet + Protexin<sup>® </sup>0.1
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Block, J. E., A. L. Friedlander, G. A. Brooks, P. Steiger, H. A. Stubbs, and H. K. Genant. "Determinants of bone density among athletes engaged in weight-bearing and non-weight-bearing activity." Journal of Applied Physiology 67, no. 3 (1989): 1100–1105. http://dx.doi.org/10.1152/jappl.1989.67.3.1100.

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To identify the factors associated with greater bone density among athletic individuals, we recruited three distinct groups of young male subjects. Twenty were nationally ranked water polo players, 19 were engaged in weight-training programs, and 20 subjects comprised a nonexercising comparison group. All participants had measurements of spinal trabecular and integral bone density by quantitative computed tomography as well as a determination of hip bone density by dual photon absorptiometry. A series of potential predictor variables included maximal O2 uptake, back strength, leg strength, tot
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Hartley, April, Celia L. Gregson, Kimberly Hannam, Kevin C. Deere, Emma M. Clark, and Jon H. Tobias. "Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity." Journals of Gerontology: Series A 73, no. 5 (2017): 652–59. http://dx.doi.org/10.1093/gerona/glx223.

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Abstract Background Sarcopenia has been associated with reduced physical activity (PA). We aimed to determine if sarcopenia, and specific components of muscle size, function, and physical performance, are associated with high impacts achieved during habitual PA, as these are related to bone strength in community-dwelling older women. Methods Participants were older women from the Cohort of Skeletal Health in Bristol and Avon. We defined sarcopenia using the EWGSOP criteria. Lower limb peak muscle power and force were assessed using Jumping Mechanography (JM). High vertical impacts were assesse
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Paccou, J., W. Bavière, R. Chapurlat, et al. "AB0815 CHANGES IN BODY COMPOSITION, BONE MINERAL DENSITY AND BONE REMODELING MARKERS DURING INTERLEUKIN 12/23 INHIBITION IN PSORIATIC ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1710.1–1710. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3176.

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Background:Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by multiple comorbid conditions including cardiovascular comorbidities, diabetes, obesity and osteoporosis. Little is known about body composition in patients with PsA and no data are available regarding body composition changes under DMARDs.Objectives:We investigated the effects of ustekinumab (UST), a humanized anti-interleukin 12/23 antibody, on body composition, bone mineral density (BMD) and bone remodeling markers in patients treated for PsA.Methods:Thirty patients with active PsA treated with UST were i
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Shoepe, Todd C., William P. McCormack, Joseph W. LaBrie, Grant T. Mello, and Hawley C. Almstedt. "Indicators of Sarcopenia: Sex Differences in Competitive Runners Prior to Peak Muscle Mass." International Journal of Sports Medicine 41, no. 14 (2020): 1067–76. http://dx.doi.org/10.1055/a-1202-1663.

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AbstractStrength, muscle mass, and muscle quality have been observed to be compromised in low body-mass index individuals such as competitive runners, increasing their risk for sarcopenia. The purpose was to compare indices of sarcopenia in young runners to age, height, body-mass, and body-mass index-matched non-runners. Handgrip strength and arm composition from dual-energy x-ray absorptiometry (baseline-T1, T2=5.3±1.4, T3=11.5±0.7 months later) were assessed in 40 non-runners and 40 runners (19.3±0.7 vs. 19.2±1.1 years, 170.7±10.3 vs. 171.1±9.1 cm, 60.2±7.4 vs. 60.2±7.9 kg, 20.6±0.9 vs. 20.5
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Xiao, Chunmei, Yong Kang, and Yong-Chang Zhuang. "Effects of Tai Chi Ball on Estrogen Levels, Bone Metabolism Index, and Muscle Strength of Perimenopausal Women." Journal of the American Geriatrics Society 63, no. 12 (2015): 2629–31. http://dx.doi.org/10.1111/jgs.13862.

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Toledo-Pérez, Rafael, Stefanie Paola Lopéz-Cervantes, David Hernández-Álvarez, et al. "Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle-Aged Wistar Female Rats." Oxidative Medicine and Cellular Longevity 2021 (August 14, 2021): 1–18. http://dx.doi.org/10.1155/2021/5294266.

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Osteosarcopenic obesity (OSO) is characterized by bone density, mass, and muscle strength loss, in conjunction with adipose tissue increase. OSO impairs physical activity and mobility, provoking autonomy loss; also, it is known that augmenting body fat in the elderly decreases life expectancy. The main factors influencing this health deterioration are the inflammatory environment induced by adipose tissue and its infiltration into muscle tissue, which leads to oxidative stress generation. Currently, there are several treatments to delay OSO, among which exercise training stands out because it
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Tada, M., Y. Yamada, K. Mandai, and N. Hidaka. "AB0265 REDUCTION OF APPENDICULAR SKELETAL MASS INDEX IS A PREDICTOR OF FRACTURE IN PATIENTS WITH RHEUMATOID ARTHRITIS BASED ON THE THREE-YEAR FOLLOW-UP DATA OF THE CHIKARA STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1431.1–1431. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2064.

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Background:Patients with rheumatoid arthritis (RA) have lower muscle mass1and a higher risk of fragility fracture2compared with healthy individuals. The predictors for fractures among baseline data and the chronological changes of disease activity, body composition, and muscle mass are unknown.Objectives:The predictors for fractures were investigated over a 3-year period in a longitudinal study.Methods:The 3-year follow-up data from a prospective observational study (CHIKARA study: Correlation researcH of sarcopenIa, sKeletal muscle and disease Activity in Rheumatoid Arthritis) were used. The
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Dobrovolskaya, O. V., N. V. Toroptsova, M. V. Cherkasova, E. Yu Samarkina, O. A. Nikitinskaya, and N. V. Dyomin. "Bone mineral density and appendicular muscle mass in patients with rheumatoid arthritis." Medical alphabet, no. 15 (2020) (September 12, 2020): 10–14. http://dx.doi.org/10.33667/2078-5631-2020-15-10-14.

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Objective. To study the bone mineral density (BMD) and appendicular muscle mass (AMM), their interrelation and relationship with calcium intake and vitamin D level in women with rheumatoid arthritis (RA).Material and methods. 43 women (mean age 57.5 ± 7.0 years) with confirmed RA were included. All patients were interviewed using a special questionnaire. Dual-energy X-ray absorptiometry (DXA) of lumbar spine, hip and total body was performed, and dietary calcium intake and vitamin D blood serum levels were assessed.Results. Reduced BMD was detected in 76.8% of patients, including osteoporosis
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Bandeira, Francisco, Natalie E. Cusano, Barbara C. Silva, et al. "Bone disease in primary hyperparathyroidism." Arquivos Brasileiros de Endocrinologia & Metabologia 58, no. 5 (2014): 553–61. http://dx.doi.org/10.1590/0004-2730000003381.

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Bone disease in severe primary hyperparathyroidism (PHPT) is described classically as osteitis fibrosa cystica (OFC). Bone pain, skeletal deformities and pathological fractures are features of OFC. Bone mineral density is usually extremely low in OFC, but it is reversible after surgical cure. The signs and symptoms of severe bone disease include bone pain, pathologic fractures, proximal muscle weakness with hyperreflexia. Bone involvement is typically characterized as salt-and-pepper appearance in the skull, bone erosions and bone resorption of the phalanges, brown tumors and cysts. In the rad
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Astuti, Yoni, Zulkhah Noor, and Rahmah Rahmah. "Sarcopenia and Bone Mass Loss as Risks during Aging on Female Elderly with Light Activity." Open Access Macedonian Journal of Medical Sciences 9, T4 (2021): 168–71. http://dx.doi.org/10.3889/oamjms.2021.5865.

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BACKGROUND: Aging is a normal physiological process. The aspect of aging can be delayed by a measurable activity that is carried out early and regularly also intake health nutrition. Measurement of body composition is needed to analyze physiological changes due to aging so it can be used to compile a program of activities also diet to delay the aging process. AIM: The aim of this study is to address the potential risks during aging process in people with light physical activity in Gamping, Patukan. METHODS: Method of this research is the cross-sectional method. Subjects were 190 females with l
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Toroptsova, N. V., O. V. Dobrovolskaya, O. A. Nikitinskaya, N. V. Demin, and A. Yu Feklistov. "Frequency of sarcopenia and factors associated with lean mass in women with rheumatoid arthritis." Terapevticheskii arkhiv 92, no. 5 (2020): 15–21. http://dx.doi.org/10.26442/00403660.2020.05.000622.

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Aim. To evaluate the frequency of sarcopenia (SP) according to EWGSOP2 criteria and factors associated with low lean mass in women with rheumatoid arthritis (RA).
 Materials and methods. 79 women (aged 4075 years) with RA were enrolled in the study. We analyzed clinical data: age, body mass index (BMI), disease duration, methotrexate use, glucocorticoid use, anthropometric measurements, C-reactive protein level, disease activity score in 28 joints-erythrocyte sedimentation rate, bone mineral density (BMD) of the lumbar spine, femur neck, total hip and body composition by Dual energy X-ray
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Cao Thi Thu, Ha, Satoshi Kurose, Yaeko Fukushima, et al. "Combining Amino Acid and Vitamin D Supplementation with Exercise Training Increases Skeletal Muscle Mass and Prevent Bone Mineral Density Loss in Participants with Low Muscle Mass." Global Journal of Health Science 10, no. 2 (2017): 28. http://dx.doi.org/10.5539/gjhs.v10n2p28.

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This study evaluated the impact of exercise training with amino acid and vitamin D supplementation on muscle and bone mass in participants with low muscle volume. Twenty-nine Japanese participants (56-84 years old) were enrolled and assigned into the supplement (n=15) and non-supplement (n=14) groups. All participants underwent a 6-month exercise program. Supplements and nutrition support were provided to the participants in the supplement group for 12 weeks. Body composition and whole bone mineral density (BMD) were measured using dual energy x-ray absorptiometry. The outcomes, including body
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Krishnamra, N., and V. Cheeveewattana. "Studies of acute effect of prolactin on distribution of absorbed calcium and long-term effect on calcium balance in weaned, young, and sexually mature rats." Canadian Journal of Physiology and Pharmacology 72, no. 12 (1994): 1521–27. http://dx.doi.org/10.1139/y94-218.

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An acute effect of a single dose of 0.02 mg prolactin/100 g body weight administered intraperitoneally on distribution of absorbed calcium and the effect of daily subcutaneous injections of 0.25 mg prolactin/100 g body weight for 13 days on calcium balance were assessed in weaned, young, and mature female rats. The acute administration of prolactin failed to affect distribution of absorbed calcium at 2 h after instillation of test solution. In contrast, the daily injection of a lower dose of prolactin over 13 days significantly decreased fecal and urinary excretion of 45Ca, an index of absorbe
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