Academic literature on the topic 'Muscle Relaxant Property'

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Journal articles on the topic "Muscle Relaxant Property"

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Priyambada, Supriya, Lakshmi Deepika P., and Singamma M. "The study of skeletal muscle relaxant property of pheniramine maleate in acetylcholine induced contractions on isolated frog rectus muscle." International Journal of Basic & Clinical Pharmacology 7, no. 3 (2018): 396. http://dx.doi.org/10.18203/2319-2003.ijbcp20180648.

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Background: A muscle relaxant is a drug which affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasm, pain and hyperreflexia. Skeletal muscle relaxants are heterogeneous group of medications that refer to 2 major therapeutic groups: neuromuscular blockers and spasmolytics. This study is carried out to evaluate the skeletal muscle property of Pheniramine maleate in Acetylcholine Induced Contractions on Isolated Frog Rectus Muscle.Methods: There are various screening techniques available to assess the muscle relaxant property of
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Sayana, Suresh Babu, Yamuna Sampathirao, Baswaraj Munge, Sachidananda Moorthy, and Kodandaramu Burli. "Comparative study of centrally acting skeletal muscle relaxants nitrazepam and thiocolchicoside in Albino mice." International Journal of Basic & Clinical Pharmacology 7, no. 6 (2018): 1182. http://dx.doi.org/10.18203/2319-2003.ijbcp20182103.

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Background: Skeletal muscle relaxants are a heterogeneous group of drugs. As a group, they are structurally and pharmacologically diverse. Skeletal muscle relaxants are usually used as adjunct therapy when initial therapy fails. They are commonly used to treat fibromyalgia, low back pain, neck pain, tension head ache, myofascial pain and muscle spasm.Methods: There were 28 mice were randomly divided into seven groups, each group consists of 4 mice. Group 1(Control): Mice were treated with normal saline and placed on rotating rod with a speed of 18 rpm (ideal speed). Group 2 (Standard-S1): Mice
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Naidu, Sushma V., and Vibha Rani. "A study to evaluate the skeletal muscle relaxant property of Pregabalin and Gabapentin in albino rats." International Journal of Basic & Clinical Pharmacology 8, no. 6 (2019): 1381. http://dx.doi.org/10.18203/2319-2003.ijbcp20192206.

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Background: Skeletal muscle relaxants are the drugs which reduce unwanted spasm without interfering with consciousness and voluntary movements. The centrally acting muscle relaxants like Diazepam, is known to be GABA mimetics and other antiepileptics like Gabapentin and Pregabalin also act through the release of GABA. This study is done to investigate skeletal muscle relaxant property of these drugs in comparison to Diazepam.Methods: T Models used in the experiment are Grip Strength Test, Rota Rod Method, Beam Walk Test, Photoactometer Test. Animals were divided into 6 groups of 6 rats each: G
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P. S, Khatavkar, Dawane J. S, and Avinash Sarak. "Study of Multifaceted Effect of Vitexnegundo Leaves Aqueous Extract and Decoction for Pain Relief in Experimental Models." Biomedical and Pharmacology Journal 14, no. 3 (2021): 1661–67. http://dx.doi.org/10.13005/bpj/2267.

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Background: Pain is the warning signal of underlying pathology. Analgesic drugs are used as per the severity of pain. These drugs have their own adverse drug reactions, sometimes requiring the discontinuation of treatment. Perception and reaction to the pain are two important facets of pain. Reaction in the form of fear,restlessness, spasm of the muscles etc. are seen. Effectiveness of Vitexnegundoin pain have been studied, we planned to evaluate the associated components of it. Objectives: To evaluate, the Analgesic action, Anxiolytic action and Muscle relaxant action of Vitexnegundo leaves a
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George, Mathew, Lincy Joseph, and Abishika Sharma. "Antidepressant and skeletal muscle relaxant effects of the aqueous extract of the Prosopis cineraria." Brazilian Journal of Pharmaceutical Sciences 48, no. 3 (2012): 577–81. http://dx.doi.org/10.1590/s1984-82502012000300025.

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The aqueous leaves extract of Prosopis cineraria (AEPC) is used traditionally for the treatment of various CNS disorder. The purpose of this study was to evaluate the extract for antidepressant and skeletal muscle relaxant activity. The antidepressant effect of the extract was evaluated using Forced swim test (FST). The immobility periods of control and treated mice were recorded. The antidepressant-like effect of tested compound was compared to that of imipramine (15 mg/kg. p.o). Muscle relaxant property was studied using rotarod apparatus and total fall off time for standard and control grou
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N., Siva Subramanian* Ch. Malathi Suvarna Pavan Kumar. Sara Elender. G. "EFFECT OF CATALYST ON SYNTHESIS OF 1, 5- BENZODIAZEPINE DERIVATIVES AND EVALUATION OF THEIR PHARMACOLOGICAL ACTIVITY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 09 (2017): 425–30. https://doi.org/10.5281/zenodo.1036399.

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1,5-Benzodiazepines are psychoactive drugs Benzene ring and Diazepine ring fusion, widely used as hypnotics, sedatives and in several Central Nervous System disorders. 1,5-Benzodiazepines are regularly used because of their nature of exhibiting pharmacological effects with minimal effect on patient performance. Derivatives of 1, 5- benzodiazepines were synthesized using the catalysts like Formic Acid and Glacial Acetic Acid, characterized by spectral studies using 1H-NMR Spectroscopy, Mass Spectroscopy, and FT-IR Spectroscopy. The results showed that the percentage yield of the reaction involv
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Chetan, S. Darne* Monika P. Maske Pawan A. Gore Jagdish R. Baheti. "Formulation and Evaluation of Antifungal and Muscle Relaxant Herbal Bath Bomb Containing Cinnamon Oil." International Journal in Pharmaceutical Sciences 1, no. 9 (2023): 355–60. https://doi.org/10.5281/zenodo.8352504.

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Bath bombs are a popular way to prepare a revitalising, soothing, and fragrant bath. It is a solid mixture of a weak acid and a strong base that does not react in dry conditions but strongly reacts with water to form salt, water, and carbon dioxide. The main aim of this research work is to prepare the medicated bath bomb and evaluated for the efficacy. The herb used in the preparations by adding plant leaf extract of cinnamon and turmeric that leaf extract has antifungal activity. Commonly bath bomb is prepared with Citric acid, Sodium Bicarbonate, Corn starch, Epsom salt, various natural colo
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Hossain, Muhammad Sazzad, Lipika Sanjowal, Mohammad Mamunur Rashid, Md Anisur Rahman Babu, and Devashis Saha. "Prevention of Succinylcholine Induced Postoperative Myalgia by Pretreatment with Lignocaine: A Randomized Controlled Study." Faridpur Medical College Journal 14, no. 1 (2020): 13–15. http://dx.doi.org/10.3329/fmcj.v14i1.46159.

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Succinylcholine, a depolarizing muscle relaxant possesses a unique property of rapid onset and short duration of action, but is accompanied by side effects such as fasciculation and myalgia. The aim of this study was to investigate the prophylactic effect of intravenous lignocaine on the incidence and severity of succinylcholine-induced postoperative myalgia. This was a randomized controlled double blind study conducted at National Institute of ENT Dhaka, during September to December 2017. Eighty adult patients of American Society of Anesthesiologists status I and II of both sexes for elective
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Murtala, A. A., and A. J. Akindele. "Anticonvulsant, Muscle Relaxant and In-vitro Antioxidant Activities of Hydroethanol Leaf Extract of Newbouldia laevis Seem. (Bignoniaceae) in Mice." University of Lagos Journal of Basic Medical Sciences 6, no. 1 & 2 (2018): 38–45. http://dx.doi.org/10.52968/23688302.

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Background: Newbouldia laevis Seem. (Bignoniaceae) is a woody tropical plant employed by traditional medicine practitioners (TMPs) in Nigeria in the treatment of various disease conditions, including central nervous system disorders. Objective: To evaluate the anticonvulsant, sedative-hypnotic, muscle relaxant and in-vitro antioxidant activities of the hydroethanol leaf extract of Newbouldia laevis (HNL). Materials and Methods: HNL (25–200 mg/kg, p.o.), distilled water (10 ml/kg, p.o.) or diazepam (3 mg/kg, p.o.) were administered 1 h before strychnine or picrotoxin-induced seizure, thiopenton
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Ito, Kaoru M., Miharu Sato, Keiko Ushijima, Masaaki Nakai, and Katsuaki Ito. "Alterations of endothelium and smooth muscle function in monocrotaline-induced pulmonary hypertensive arteries." American Journal of Physiology-Heart and Circulatory Physiology 279, no. 4 (2000): H1786—H1795. http://dx.doi.org/10.1152/ajpheart.2000.279.4.h1786.

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We examined how monocrotaline (MCT), which impairs the endothelium and causes pulmonary hypertension, altered the endothelial regulation of pulmonary artery functions. Rats were given a single injection of MCT (60 mg/kg sc). Pulmonary arteries were depolarized to −48.3 ± 2.6 and −39.8 ± 2.2 mV at 2 and 3 wk after treatment with MCT, respectively (control arteries −59.9 ± 1.9 mV). The basal tone in the resting state was only slightly elevated at 3 wk in endothelium-intact arteries. Removal of the endothelium caused further depolarization in MCT-affected arteries at 2 wk, but not at 3 wk, and gr
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Book chapters on the topic "Muscle Relaxant Property"

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Abrams, Richard. "Technique of Electroconvulsive Therapy: Praxis." In Electroconvulsive Therapy. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780195148206.003.0009.

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Abstract The following is a specific treatment sequence that I find useful for administering ECT. It assumes that the patient has been properly prepared for treatment as outlined earlier and is lying on a stretcher in the treatment room, that vital signs have been recorded, and that all necessary staff personnel are in attendance. At the beginning of the treatment day, each patient’s individual doses of intravenous medications and saline should be drawn up into separate syringes, labeled with the patient’s name, date, type and dose of medication, and placed together in a small container marked
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Farag, Ehab, and Zeyd Ebrahim. "Anaesthesia for Complex Spine Surgeries." In Oxford Textbook of Neuroscience and Anaesthesiology, edited by George A. Mashour and Kristin Engelhard. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198746645.003.0020.

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This chapter discusses the pre-operative evaluation of the patient scheduled for complex spine surgery, and focuses on functional capacity, neurological assessment, and upper airway examination. In patients undergoing cervical spine surgery, awake fibreoptic intubation may be the safest technique for upper airway management, especially in patients with significant spinal cord compression or unstable cervical spine. Increased intra-ocular pressure during spine surgery in the prone position may compromise the ocular perfusion pressure. Maintaining proper ocular perfusion pressure is crucial to a
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Adrianne Deutsch, Judith, Kata Šakić, Dinko Bagatin, Johann Nemrava, and Tomica Bagatin. "Anesthesia in Plastic Surgery: Intersurgical I-gel Placement in a Prone Position." In Updates in Anesthesia - The Operating Room and Beyond [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106538.

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Anesthesia is a specialization which in past history has branched off of surgery. It needs to be very creative in its delivery, in order to accommodate the many operating positions, needed by the surgeon. The patient positions must also be safe and adequate for proper ventilation, throughout the operative procedure. There are times when multiple positions must be used, turning the patient over, even several times. Careful planning and team discussions prior to an operation are absolutely necessary, to form anesthetic and operative plans. The aim of the supraglottic airway device (Intersurgical
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Clark, Matthew D. "Non-Opioid Analgesic Side Effects." In Pain. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197542873.003.0014.

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The euphoric effects of opioids have been understood since the Mesopotamian period when spiritual leaders used opium to relieve grief, worry, and regret. Opioid use has risen since the nineteenth century, leading to the crisis known today as the “opioid epidemic.” This resulted in an increase in opioid-related morbidity and mortality. In the midst of this epidemic, healthcare providers can turn to non-opioid analgesics for non-malignant pain. Agents such as acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), antidepressants, anticonvulsants, muscle relaxants, and corticosteroids are
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