Relevant bibliographies by topics / Musculoskeletal diseases in old age

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Musculoskeletal diseases in old age'

Author: Grafiati
Published: 4 June 2021
Last updated: 21 February 2023

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Journal articles on the topic "Musculoskeletal diseases in old age"

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Calderón-Larrañaga, Amaia, Laura Pérez, Davide Vetrano, Federico Triolo, Linnea Sjöberg, Alexander Darin-Mattsson, Marco Inzitari, and Shireen Sindi. "Sleep Disturbances and the Speed of Multimorbidity Development in Old Age." Innovation in Aging 5, Supplement_1 (December 1, 2021): 377. http://dx.doi.org/10.1093/geroni/igab046.1462.

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Abstract Sleep disturbances are prevalent among older adults and are associated with various individual diseases. The goal of this study was to investigate whether sleep disturbances are associated with the speed of multimorbidity development among older adults. Data were gathered from the Swedish National study of Aging and Care in Kungsholmen (SNAC-K), an ongoing population-based study of subjects aged 60+ (N=3363). The study included a subsample (n=1189) without multimorbidity at baseline (<2 chronic diseases). Baseline sleep disturbances were assessed using the Comprehensive Psychiatric Rating Scale, and categorized as none, mild, moderate-severe. The number of chronic conditions throughout the nine-year follow-up was obtained from clinical examinations. Linear mixed models were used to study the association between sleep disturbances and the speed of chronic diseases accumulation, adjusting for sex, age, education, physical activity, smoking, alcohol consumption, depression, pain, and psychotropic drug use. We repeated the analyses including only cardiovascular, neuropsychiatric, and musculoskeletal diseases as the outcome. Moderate-severe sleep disturbances were associated with a higher speed of chronic disease accumulation (ß/year=0.142, p=0.008), regardless of potential confounders. Significant positive associations were also found between moderate-severe sleep disturbances and neuropsychiatric (ß/year=0.041, p=0.016) and musculoskeletal (ß/year=0.038, p=0.025) disease accumulation, but not with cardiovascular diseases. Results remained stable when participants with baseline dementia, cognitive impairment, or depression were excluded. The finding that sleep disturbances are associated with faster chronic disease accumulation points towards the importance of early detection and treatment of sleep disturbances as a possible strategy to reduce chronic multimorbidity among older adults.
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Elistratov, Dmitry G. "Application of bioregulatory osteoprotectors in old age to reduce drug load in diseases of the musculoskeletal system." Meditsinskaya sestra 24, no. 3 (2022): 41–45. http://dx.doi.org/10.29296/25879979-2022-03-08.

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Elistratov, Dmitry G. "Application of bioregulatory osteoprotectors in old age to reduce drug load in diseases of the musculoskeletal system." Meditsinskaya sestra 24, no. 3 (2022): 41–45. http://dx.doi.org/10.29296/25879979-2022-03-08.

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Elistratov, Dmitry G. "Application of bioregulatory osteoprotectors in old age to reduce drug load in diseases of the musculoskeletal system." Meditsinskaya sestra 24, no. 3 (2022): 41–45. http://dx.doi.org/10.29296/25879979-2022-03-08.

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Rodionov, Stanislav. "Indicator of geoecological assessment of the region - population health." E3S Web of Conferences 244 (2021): 01002. http://dx.doi.org/10.1051/e3sconf/202124401002.

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The article shows that an effective indicator of the level of pollution of air, water and soil with toxic compounds of anthropogenic origin is a health of the population in different age groups. As eco-indicators, it is proposed to use diseases of the respiratory system for people under 18 years old, the circulatory and digestive systems - 18-56 years old, the musculoskeletal system - over 56 years old. To carry out ecological diagnostics of negative changes in the natural environment of urbanized areas of small towns, we propose to assess the response (reaction) – hospitalization rate in different age groups of the population: under 18 years old, 19-55 years old, and over 56 years old.
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Bolobonkina, Tatyana A., Aleksej A. Dementyev, and Natalya V. Minaeva. "Prevalence and risk of chronic diseases in medical personnel of mobile ambulance teams." I.P. Pavlov Russian Medical Biological Herald 29, no. 4 (December 15, 2021): 483–88. http://dx.doi.org/10.17816/pavlovj64284.

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Introduction: Medical workers of mobile ambulance teams (MATs) are at a high risk of exposure to harmful working conditions, leading to the development of chronic diseases (CDs). Aim: To study the prevalence and risks of the development of CDs according to the results of a sociological survey among medical workers of MATs. Materials and methods: The method used for the sociological research was based on a specially designed questionnaire using Google Forms electronic service. The survey was participated by 176 medical workers. The average age of the respondents was 40.58 14.01 years, of which 143 were women and 33 were men. Results: Of the majority of the respondents (63.6%), 51.5% were 1825 years old with working period 5 years, who had CDs; 89.5% were 5160 years old, and 100% were 61 years old. The most common forms of CDs were diseases of the musculoskeletal system, digestive organs, respiratory organs, urogenital system, and circulatory system, and the prevalence ranged from 25.6 to 15.3 per 100 respondents. In the total cohort, 74.8% had chronic morbidity. The medical personnel of general ambulance teams had significantly higher relative risk (RR) of CDs (2.449 [95% confidence interval, CI 1.7013.525]) than those of specialized ambulance teams. Gender and occupational differences in the development of musculoskeletal pathologies were found, with higher RRs among women (RR 4.510 [95% CI 1.15517.610]) and medical personnel of MATs (RR 1.874 [95% CI 1.0413.374]). Conclusions: The prevalence of certain CDs among medical workers of MATs depends on the duration of contact with occupational factors, gender, and age of the workers.
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Gromakina, E. V., N. V. Tyunina, E. D. Egorova, and E. A. Sozurakova. "Pathogenetic aspects of cataract in comorbid conditions." Modern technologies in ophtalmology, no. 5 (September 30, 2022): 65–68. http://dx.doi.org/10.25276/2312-4911-2022-5-65-68.

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Relevance. Research by ophthalmologists, biologists, biochemists, biophysicists, physiologists have shown the significance of xeno- and endobiotic effects on the induction of cataracts and other degenerative diseases of the structures and membranes of the eye. Objective research goal was an evaluation of comorbid background in people of different ages with a diagnosis of senile cataract. Material and methods an analysis of the case histories of 173 patients of an independent sample with a diagnosis of "senile cataract" admitted for planned inpatient surgical treatment was carried out. The evaluation was carried out by decades of human life: younger than 40 years old, 41–50 years old, 51–60 years old, 61–70 years old, 71–80 years old and over 80 years old. The Charlson method was used to calculate the comorbidity index. Results patients who had senile cataract and concomitant somatic diseases, the most frequent- diseases of the cardiovascular system – 129 (74.6 %); violation of carbohydrate metabolism – 35 (20.2 %); diseases of the central nervous system – 33 (19.1 %); musculoskeletal system – 30 (17.3 %); diseases of the respiratory system – 19 (11.0 %). Conclusions. 1. A human's age of 51–60 years should be considered critical for the occurrence of senile cataract. 2. In the decade of life 51–60 years, there is an increase in persons with senile cataract by 3.3 and the frequency of concomitant somatic pathology (according to the index of comorbidity) by 2.25. Keywords: senile cataract, age, somatic diseases, index of comorbidity
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Pilipenko, A., V. Mazurov, and I. Gaydukova. "AB1208 FREQUENCY OF MUSCULOSKELETAL AND OTHER EXTRA-INTESTINAL SYMPTOMS IN PATIENTS WITH CELIAC DISEASE." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1719.1–1719. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4278.

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BackgroundCeliac disease (CD) is one of the most common gastrointestinal tract diseases, in adults and children. Prevalence of CD is 1-3% [2]. The most common symptoms of CD are gastrointestinal symptoms. At the same time, celiac disease may manifest with extraintestinal symptoms, including the musculoskeletal, nervous, reproductive system, and skin, especially when it debuts at a late age [1,2]. However, data about musculoskeletal manifestations of CD are limited.ObjectivesTo show the frequency of musculoskeletal complaints and their peculiarities in patients with CD.MethodsData from 94 patients with diagnosed by gastroenterologist celiac disease were collected with the on-lain survey. All the patients were positive in CD-related immunological and genetic tests and had biopsy established CD.ResultsТhe average age of respondents is 37,52 ± 11,2 years, women 79 (84,1%), men 15 (15,9%). Among 94 respondents 0.1% do not follow a gluten-free diet, 10.6% <1 year, 25.5% from 1 to 3 years, 11.7% – 4-5 years, 28.7% are on a gluten-free diet >5 years, 14.9% – 10-15 years, 8.5% > 15 years. Gastrointestinal symptoms have started at the age < 10 years old in 59.6% of patients, in 4.2% in 11-16 years old, 13.8% at the age 17-25 years old, 12.8% at the age 26-40 years old, 9.6% had late CD onset (>40 years old).Extraintestinal symptoms such as drowsiness were noted by 46.8 %, headaches by 40.4%, weakness by 59.6%, irritability by 57.4% of respondents. Lack of coordination was noticed in 18.1% of cases, dizziness in 22.3%, 57.4% have numbness, decreased sensitivity, and tingling feeling in the limbs. Joint pain had 54.3% of the patients with CD (Figure 1).Figure 1.Frequency of pain in different jointsThe maximal intensity of pain was noticed in the morning (8.5%) or late night (13.8%) times and fulfilled inflammatory pain criteria (ASAS). In 17% was noticed interrelation between gluten-free diet violation and the appearance of joint pain. In 26.6% was noticed signs of enthesitis. Weakness of arms was noticed by 39.4% of respondents. Non-steroidal anti-inflammatory drugs (NSAIDs) were started by 35.1% of patients, without any improvement in 66% of cases.ConclusionPatients’ surveys showed that musculoskeletal symptoms in patients with celiac disease are not a rare problem and they are comparable with the frequency of neurological symptoms. Additional research is necessary for a better understanding of the nature of musculoskeletal involvement in celiac disease.References[1]Admou, B., et al. https://doi.org/10.1155/2012/637187.[2]Laurikka P., et al. https://doi.org/10.3390/nu10081015Disclosure of InterestsNone declared
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Solovieva, Svetlana, Karina Undem, Daniel Falkstedt, Gun Johansson, Petter Kristensen, Jacob Pedersen, Eira Viikari-Juntura, Taina Leinonen, and Ingrid Sivesind Mehlum. "Utilizing a Nordic Crosswalk for Occupational Coding in an Analysis on Occupation-Specific Prolonged Sickness Absence among 7 Million Employees in Denmark, Finland, Norway and Sweden." International Journal of Environmental Research and Public Health 19, no. 23 (November 25, 2022): 15674. http://dx.doi.org/10.3390/ijerph192315674.

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We identified occupations with a high incidence of prolonged sickness absence (SA) in Nordic employees and explored similarities and differences between the countries. Utilizing data from national registers on 25–59-year-old wage-earners from Denmark, Finland, Norway and Sweden, we estimated the gender- and occupation-specific age-adjusted cumulative incidence of SA due to any cause, musculoskeletal diseases and mental disorders. To increase the comparability of occupations between the countries, we developed a Nordic crosswalk for occupational codes. We ranked occupational groups with the incidence of SA being statistically significantly higher than the population average of the country in question and calculated excess fractions with the employee population being the reference group. We observed considerable occupational differences in SA within and between the countries. Few occupational groups had a high incidence in all countries, particularly for mental disorders among men. In each country, manual occupations typically had a high incidence of SA due to any cause and musculoskeletal diseases, while service occupations had a high incidence due to mental disorders. Preventive measures targeted at specific occupational groups have a high potential to reduce work disability, especially due to musculoskeletal diseases. Particularly groups with excess SA in all Nordic countries could be at focus.
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Halonen, Jaana I., Rahman Shiri, Minna Mänty, Hilla Sumanen, Svetlana Solovieva, Eira Viikari-Juntura, Mika Kähönen, Terho Lehtimäki, Olli T. Raitakari, and Tea Lallukka. "Exposure to heavy physical work from early to later adulthood and primary healthcare visits due to musculoskeletal diseases in midlife: a register linked study." BMJ Open 9, no. 8 (August 2019): e031564. http://dx.doi.org/10.1136/bmjopen-2019-031564.

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ObjectivesTo examine whether exposure to heavy physical work from early to later adulthood is associated with primary healthcare visits due to cause-specific musculoskeletal diseases in midlife.DesignProspective cohort study.SettingNationally representative Young Finns Study cohort, Finland.Participants1056 participants of the Young Finns Study cohort.Exposure measurePhysical work exposure was surveyed in early (18–24 years old, 1986 or 1989) and later adulthood (2007 and 2011), and it was categorised as: ‘no exposure’, ‘early exposure only’, ‘later exposure only’ and ‘early and later exposure’.Primary and secondary outcome measuresVisits due to any musculoskeletal disease and separately due to spine disorders, and upper extremity disorders were followed up from national primary healthcare register from the date of the third survey in 2011 until 2014.ResultsPrevalence of any musculoskeletal disease during the follow-up was 20%, that for spine disorders 10% and that for upper extremity disorders 5%. Those with physically heavy work in early adulthood only had an increased risk of any musculoskeletal disease (risk ratio (RR) 1.55, 95% CI 1.05 to 2.28) after adjustment for age, sex, smoking, body mass index, physical activity and parental occupational class. Later exposure only was associated with visits due to any musculoskeletal disease (RR 1.46, 95% CI 1.01 to 2.12) and spine disorders (RR 2.40, 95% CI 1.41 to 4.06). Early and later exposure was associated with all three outcomes: RR 1.99 (95% CI 1.44 to 2.77) for any musculoskeletal disease, RR 2.43 (95% CI 1.42 to 4.14) for spine disorders and RR 3.97 (95% CI 1.86 to 8.46) for upper extremity disorders.ConclusionsTo reduce burden of musculoskeletal diseases, preventive actions to reduce exposure to or mitigate the consequences of physically heavy work throughout the work career are needed.
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Dissertations / Theses on the topic "Musculoskeletal diseases in old age"

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陸凱縈 and Hoi-ying Victoria Luk. "How does population aging affect disease control among old age from a public health perspective." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42997495.

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Pearson, Melanie A. "Cardiovascular adaptability influences cortical neuronal activation in very old adults /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3137735.

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Luke, Baw D. "Educational attainment and cardiovascular disease related mortality a retrospective cohort evaluation of Chinese elderly population in Hong Kong /." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41711373.

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陸坡 and Baw D. Luke. "Educational attainment and cardiovascular disease related mortality: a retrospective cohort evaluation ofChinese elderly population in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41711373.

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Compte, Nathalie. "Impact of clinical factors on inflammaging and Toll-like receptors responses in old age." Doctoral thesis, Universite Libre de Bruxelles, 2014. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209155.

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Le vieillissement s’accompagne d’une altération globale des fonctions physiologiques notamment celles de l’immunité :on parle « d’immunosénescence ». Ce processus se traduit entre autre par l’installation d’un état inflammatoire chronique caractérisé par une augmentation des taux sériques de cytokines telles que l’interleukine(IL)-6 et des protéines de la phase aigüe. Cet état proinflammatoire serait incriminé dans le déclin des fonctions physiologiques, la fragilité et les syndromes gériatriques. Par ailleurs, les maladies cardiovasculaires, la dépression et l’infection chronique par le Cytomégalovirus (CMV) sont également associés à un état inflammatoire chronique. La prévalence de ces comorbidités étant importante chez les patients gériatriques, ces maladies pourraient donc contribuer à l’association observée entre marqueurs de l’inflammation et les syndromes gériatriques.

Les infections représentent un problème majeur en gériatrie. Les cellules du système immunitaire inné jouent un rôle important dans les défenses contre les agents pathogènes. La reconnaissance de ceux-ci par les cellules dendritiques, les macrophages ou les monocytes fait intervenir une série de molécules telles que les récepteurs de la famille Toll (TLR). Certains travaux suggèrent que la fonction des cellules de l’immunité innée pourrait être perturbée chez les individus âgés mais ces données restent controversées.

Dans ce travail, nous souhaitons aborder les hypothèses suivantes :

•\
Doctorat en Sciences médicales
info:eu-repo/semantics/nonPublished

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Yu, Li, and 于力. "The association between floor level of residence and mortality of elders living in public housing estates in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46944047.

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Tan, Boon-Kiang. "Non-invasive determinants of osteoporotic fracture risk." University of Western Australia. Centre for Musculoskeletal Studies, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0125.

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[Truncated abstract] The cost of managing osteoporotic fractures places a significant financial burden on the health-care system. To reduce the fracture burden, early identification of fracture risk is essential to allow early intervention. The limitations associated with dual-energy X-ray absorptiometry (DXA), such as limited sensitivity and specificity, cost, ionising radiation and accessibility, have resulted in the emergence of other technologies for assessing bone fragility. An example is the portable and non-ionising quantitative ultrasound (QUS) technology. The discriminatory power of quantitative ultrasonometry in fracture risk identification, either independently or in combination with other established risk factors, currently remains contentious. It is recommended that fracture risk assessment should not only focus on bone status, but also on the risk of falls. Additionally, it has been noted that disability arising from osteoporotic fractures, even when these fractures are not identified clinically, can translate into psychosocial symptoms and a poorer perception of health-related quality of life (HRQoL). The primary aim of the present study was to investigate if a composite model comprising: calcaneal QUS, falls risk and HRQoL assessments, can identify a group of elderly women at high risk of osteoporotic fracture from those at lower risk. One hundred and four community-dwelling women (mean age 71.3 ±5.8 years) were recruited for this study. These women underwent a series of tests that included: DXA bone mineral density (BMD) evaluation of the proximal femur and lumbar spine (L1 L4); calcaneal QUS measurement; spinal radiography; rasterstereographic back surface curvature (BSC) examination; and performance-based assessment of strength, mobility and balance. The women were classified into a `High Risk’group or a `Low Risk’ group using three separate classification criteria: i) low BMD, based on the World Health Organisation (WHO) recommended T-score of < -2.5, and⁄or a history of fragility fracture (Osteoporotic [OP] group versus Non-Osteoporotic [NOP] group); ii) presence of at least one radiographically identified prevalent vertebral fracture (Vertebral Fracture [VF] group versus Non-Vertebral Fracture [NVF] group); or iii) a history of either forearm or wrist fracture (Forearm/Wrist Fracture [WF] group versus Non-Forearm/Wrist Fracture [NWF] group)
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Ajwani, Shilpi. "Periodontal disease in an aged population, and its role in cardiovascular mortality." Helsinki : University of Helsinki, 2003. http://ethesis.helsinki.fi/julkaisut/laa/hamma/vk/ajwani/.

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Lee, Kwok-lun, and 李國綸. "The oral epidemiology of 45-64 year-old Chinese residents of a housingestate in Hong Kong: coronal and rootcaries." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B38628260.

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Leijon, Margareta. "Integrating perspectives in social medicine : a study using epidemiological and clinical methods with special reference to sickness absence /." Linköping : Univ, 2002. http://www.bibl.liu.se/liupubl/disp/disp2002/med754s.pdf.

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Books on the topic "Musculoskeletal diseases in old age"

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1949-, Perry Horace M., Morley John E, and Coe Rodney M, eds. Aging and musculoskeletal disorders: Concepts, diagnosis, and treatment. New York: Springer Pub. Co., 1993.

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Reenie, Euhardy, ed. Coping with impaired mobility. San Diego, Calif: Singular Pub. Group, 1994.

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Skin disease in old age. London: Martin Dunitz, 1990.

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Alan, Sinclair, and Finucane Paul 1955-, eds. Diabetes in old age. 2nd ed. Chichester: John Wiley, 2001.

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Skin disease in old age. 2nd ed. London: Dunitz, 1999.

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Skin disease in old age. Philadelphia: J.B. Lippincott Co., 1987.

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Spilsbury, Louise. Health and disease: From birth to old age. Chicago, Ill: Capstone Heinemann Library, 2013.

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Shah, Ebrahim, and Kalache Alex, eds. Epidemiology in old age. London: BMJ Publishing Group in collaboration with the World Health Organization, 1996.

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Raymond, Tallis, ed. The clinical neurology of old age. Chichester: Wiley, 1989.

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L, Deecke, Dal-Bianco P. 1951-, and Central-European Neurological Symposium (19th : 1989 : Vienna, Austria), eds. Age-associated neurological diseases. Wien: Springer-Verlag, 1991.

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Book chapters on the topic "Musculoskeletal diseases in old age"

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Seely, S. "Is Old Age A Diet-Related Disease?" In Diet-Related Diseases, 263–66. London: Routledge, 2022. http://dx.doi.org/10.1201/9781003284369-9.

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de Berker, David A. R., Bertrand Richert, and Robert Baran. "The Nail in Childhood and Old Age." In Baran & Dawber's Diseases of the Nails and their Management, 183–209. Oxford, UK: Blackwell Publishing Ltd., 2012. http://dx.doi.org/10.1002/9781118286715.ch4.

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Hayflick, Leonard. "Modulating Aging, Longevity Determination and the Diseases of Old Age." In Modulating Aging and Longevity, 1–15. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-017-0283-6_1.

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Müller, Britta, and Lea Ellwardt. "Social Networks and Health Inequalities in Old Age." In Social Networks and Health Inequalities, 181–202. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-97722-1_10.

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AbstractThanks to improvements in living standards and health behavior as well as medical progress since the second half of the twentieth century, old age has become a life phase in its own right. This phase usually begins by the transition from working life to retirement (Kohli, 2000). Both the chance of reaching retirement and the life expectancy after retirement have increased significantly (Eisenmenger & Emmerling, 2011). The post-work phase spans several decades for many people now. In addition, people who retire are considerably healthier and more independent than their peers of earlier birth cohorts (Crimmins, 2004). The expansion of this phase of life has been accompanied by a differentiation of older people in terms of health and independence: healthy and active people experience this phase, as do people in need of help and care. This fact is considered by distinguishing between old and very old people (Baltes, 2007). Characteristics of old age are absence of non-compensable health restrictions, self-determination of various activities (e.g., traveling, hobbies, voluntary work), and strong social integration. Overall, the demands of old age can be coped well in this phase. Very old age is characterized by an increase in physical and cognitive losses and diseases, and a decrease in the abilities and possibilities of compensating for deficits (Baltes, 1997; Baltes & Smith, 2003).
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Maresova, Petra, Hana Tomaskova, and Kamil Kuca. "The Use of Simulation Modelling in the Analysis of the Economic Aspects of Diseases in Old Age." In Business Challenges in the Changing Economic Landscape - Vol. 1, 369–77. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22596-8_26.

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von Gunten, Armin, Eduardo Nogueira, Henk Parmentier, and Irênio Gomes. "Neurocognitive Disorders in Old Age: Alzheimer’s Disease, Frontotemporal Dementia, Dementia with Lewy Bodies, and Prion and Infectious Diseases." In Primary Care Mental Health in Older People, 251–98. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-10814-4_21.

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Meslé, France, and Jacques Vallin. "Causes of Death at Very Old Ages, Including for Supercentenarians." In Demographic Research Monographs, 69–84. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-49970-9_7.

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AbstractThe causes of death reported on the death certificates of the oldest old are generally seen as unreliable, and as thus providing little useful information on the process leading to death. However, in advanced countries, a majority of the people who die each year are relatively old, and the level of detail provided on medical certificates about the causes of death among this older population is improving. At the same time, scholars are becoming increasingly interested in studying not just the initial cause of death, but multiple causes of death, thereby taking all of the information reported on the certificate into account. This study demonstrates that in a country like France, the cause-of-death pattern evolves regularly until around age 105. The share of people dying of circulatory diseases tends to be quite stable over the age range, while the share of individuals dying of cancer is declining, and the share of people dying of respiratory/infectious diseases is rising. Furthermore, among people who die at very old ages, a typology of multiple causes of death highlights the growing importance of ill-defined causes, while opening the door to an interesting discussion about the concept of cause of death in the supercentenarian population. Instead of representing an ill-defined cause, senility could be considered an actual cause of death. This suggests that daily care is more crucial to the survival of the oldest old than any conventional medical care or treatment. Supercentenarians tend to be so frail that any minor health event or brief lapse of attention on the part of their caregivers can be lethal.
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Barclay, Katie, and François Soyer. "André du Laurens (1558–1609), A Discourse of the Preseruation of the Sight: of Melancholike Diseases; of Rheumes, and of Old Age." In Emotions in Europe 1517–1914, 266–74. London: Routledge, 2021. http://dx.doi.org/10.4324/9781003175384-48.

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Kaalby, Lasse, Axel Skytthe, Karen Andersen-Ranberg, and Bernard Jeune. "Causes of Death Among 9000 Danish Centenarians and Semisuper-Centenarians in the 1970–2012 Period." In Demographic Research Monographs, 85–102. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-49970-9_8.

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AbstractAs most centenarians suffer from multiple diseases, they are at high risk of dying – but what do they ultimately die of? This question has scarcely been examined. We have carried out a register-based study of the causes of death (CoD) among Danish centenarians. Among 8559 centenarian deaths in the 1970–2012 period, the most common CoD was in the category of cardio- and cerebrovascular diseases (CVD); at the end of the study period, this CoD accounted for one-third of the deaths in this age group. The mortality rate for CVD as an underlying CoD was more than halved during the period (from 358 to 170 per 1000 person-years). In contrast, the mortality rate for cancer remained stable during the whole period, but at a very low level (15–20 per 1000 person-years). Cancer made up a much smaller share of underlying CoDs among this age group (3–4%) than among 85–99-year-olds (15%). The mortality rate for pneumonia remained at a constant level (about 50 per 1000 person-years) of around 10% among centenarians and 5% among 85–99-year-olds. The underlying CoD groups that were reported with increasing frequency during the period were mental diseases, including dementia, which increased sevenfold; and ill-defined conditions/senility, which increased fourfold. The latter CoD group accounted for 28% of deaths among centenarians in the most recent years, and for more than one-third of deaths among semi-supercentenarians (aged 105–109). The increase in the proportion of deaths for which the CoD was listed as ill-defined conditions/senility was probably partly due to the under-diagnosis of diseases among centenarians, especially of heart diseases. However, a substantial proportion of these deaths may have been attributable to “old age” – i.e., a combination of several diseases and organ deficiencies – and not to a single underlying cause.
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Skoog, Ingmar, Hanna Falk Erhag, Silke Kern, Therese Rydberg Sterner, Jessica Samuelsson, and Anna Zettergren. "The Capability Approach in Epidemiological Studies." In International Perspectives on Aging, 29–50. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-78063-0_4.

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AbstractPopulation epidemiology is the science that deals with disorders and certain conditions at the population level, i.e. at the macro-level. In contrast to experimental studies, the scientist in epidemiology cannot manipulate conditions to make studies of associations as pure as possible. The science of epidemiological studies examines the occurrence of diseases, risk and protective factors for diseases, and the prognosis of different disorders and conditions in different populations. The capability approach is an ideal framework for epidemiological studies because it captures the dynamic and multiple processes involved in these types of studies, in relation to both time and space, as well as socioeconomic, psychological and biological factors. Determinants for common disorders and conditions include complex interactions among a multitude of factors acting between and within macro-, meso- and micro-levels during the life-course of an individual. In this chapter, we will discuss how the capability approach can be used in epidemiology in general, and in old age in particular, giving examples from specific conditions, such as cognitive function and dementia, depression, multimorbidity and functional ability, and non-modifiable and modifiable risk factors, such as genetics and nutrition. We conclude that the capability approach is a valuable tool in epidemiological studies. In these types of studies, capability is the final outcome of the dynamic interactions between a multitude of factors at the micro-, meso- and macro-levels leading to disorders and other conditions, which leads to restrictions in the individual’s ability to perform actions in order to reach goals he or she has reason to value.
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Conference papers on the topic "Musculoskeletal diseases in old age"

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Sadikova, Daniela. "ASSESSMENT OF BODY POSTURE OF 6-7 YEARS OLD CHILDREN IN RELATION TO THE BMI." In INTERNATIONAL SCIENTIFIC CONGRESS “APPLIED SPORTS SCIENCES”. Scientific Publishing House NSA Press, 2022. http://dx.doi.org/10.37393/icass2022/155.

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ABSTRACT Introduction: Increased weight in childhood is a determining factor in developing several diseases in adulthood. The poor posture of the child might be a result of the rapidly growing musculoskeletal system, the increased BMI, or a combination of both. This study aims to investigate the relation between BMI and poor posture in 7-6 years old children. Material and Methodology: The study included 2 kindergartens in Sofia and was held in September 2018. The New York Posture Rating Chart was used to evaluate the posture. The anthropometric data were assessed and the BMI was calculated by BMI-for-age (5-19) years. The screening covered 112 children with a mean age of 6.14 years. Results: Poor posture was identified in 32 (28.5%) of the subjects. Abnormal BMI was amounted to 22 (19.6%) of the children: 4 (3.5%) underweight, 16 (14.3%) overweight and 2 (1.7 %) obese. The increase in BMI correlated with a higher chance of poor posture was identified by almost 11.6 % of the pupils.
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Agzamova, G. S., N. U. Ibragimova, and Yu A. Abdieva. "PREVENTION ISSUES OF OCCUPATIONAL AND PRODUCTION-RELATED DISEASES IN MINING INDUSTRY WORKERS." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-12-15.

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Abstract: Protecting and promoting the health of workers in the mining industry is one of the most important problems of occupational pathology and health care. The structure and levels of prevention of occupational diseases are directly dependent on harmful and adverse factors of the production environment and labor process, adequately reflecting the state of production. Purpose: to study the issues of prevention of occupational and production-related diseases of mining and metallurgical plant workers. Research materials and methods: a dynamic observation of the health status of workers in the main industries of the mining and metallurgical plant (800 workers) was carried out. 92 patients with silicosis were examined. Results: Up to 92.8% of first-time occupational diseases are detected during periodic medical examinations. The prevailing sociomatic pathology is cardiovascular pathology, namely, arterial hypertension and diseases of the musculoskeletal system, mainly osteochondrosis of the spine. Prevalence of silicosis was observed in individuals with little professional experience (from 5 years old), young age and primary detection of patients in stage II silicosis, which was accompanied by respiratory failure. Conclusions: The prevention programme developed will ensure a high level of health care in terms of early diagnosis, rehabilitation and secondary prevention of both occupational and occupational diseases.
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Lima, Rebeca Menezes de Oliveira, Caio Lopes Pereira Santos, Gabriela Malta Coutinho, Natalia Guerreiro Costa Neeser, and Tauá Vieira Bahia. "Epidemiological profile of neurological diseases in Brazil from 2011 to 2020." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.240.

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Background: Studying the epidemiology of neurological diseases is important to improve the Public System. Objectives: To describe the epidemiological profile of neurological diseases in Brazil between 2011 and 2020. Design and setting: Ecological study in Brazil. Methods: Data was collected from the Ministry of Health, through DATASUS. The period analyzed was between 2011 and 2020. The data collected were region, age, deaths, mortality rate, and average stay due to neurological diseases. Results: 1,833,363 hospitalizations were recorded, with 89,046 deaths. The age group from 50 to 54 years old was the most hospitalized (147,832 cases) and the 80 years and over had the highest mortality rate (14.9). The average stay averages were 13.1 days and the average lethality rates were 4.9. Furthermore, the highest average prevalence of cases per 100,000 inhabitants occurred in the South (142), while the lowest was in the North (49). However, there was a higher mortality rate in the North (6.2) than in the South (4.2). Conclusions: The highest mortality rate in the age of 80 years and over may be associated whit the effects of old age. Moreover, the lowest prevalence of cases and the highest mortality rate in North is possibly related to a deficiency in the diagnosis and treatment of this diseases in that location.
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Steshyn, V. D., and M. V. Sinelyova. "PREVALENCE OF DISEASES OF THE BLOOD CIRCULATION SYSTEM AMONG DIFFERENT GENDER AND AGE GROUPS." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-118-121.

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An analysis of the incidence of the population of Minsk with diseases of the circulatory system showed that there is an increase in both the primary and general incidence of various forms of cardiovascular diseases from 2018 to 2019 among different gender and age groups. The highest values of both general and primary morbidity from diseases of the circulatory system for both sexes were observed in the age group over 60 years old. The leading form in this age group was ischemic heart disease, occurring against the background of arterial hypertension.
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Shaforenko, D. D., and I. V. Puhteeva. "COMPARATIVE ANALYSIS OF THE PREVALENCE OF DISEASES OF THE BONE-MUSCLE SYSTEM AND CONNECTIVE TISSUE IN THE POPULATION OF THE REPUBLIC OF BELARUS AND GOMEL REGION FOR 2010-201." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute, 2021. http://dx.doi.org/10.46646/sakh-2021-1-364-367.

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The evaluation of indicators that characterize the features of the formation of population’s health over a long period of time such as general and primary morbidity, disability and mortality in children, and the population of older working age. The obtained data indicate that in the Republic of Belarus and in the Gomel region the incidence of the given group of diseases tends to increase. Gomel region is one of the three regions for this indicator. Diseases of the musculoskeletal system and connective tissue occupy one of the leading positions among the causes of disability among the population in the Republic and in the Gomel region. This indicator tends to grow. The mortality rate due to diseases of the musculoskeletal system and connective tissue in the Republic of Belarus and in the Gomel region is quite small. There is no mortality among children.
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Gardinier, Joseph D., Fatma Mohamed, and David H. Kohn. "Systemic PTH Release During Exercise Enhances Trabecular Bone Architecture." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14304.

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Bone mineral density gained during adolescent years is a significant determinant of bone quality maintained during adult-hood [1]. The ability to enhance the structural integrity of bone at a young age reduces the risk of bone fracture as well as the development of musculoskeletal diseases, such as osteoporosis [1].
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Pechuro, E. A., A. N. Batian, V. А. Kravchenko, and S. V. Petrenko. "THYROID DISEASES IN THE RESIDENTS OF THE CITY LOCATION OF THE STOLINSKY DISTRICT OF THE BREST REGION FOR THE PERIOD FROM 2016 TO 2020." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute, 2021. http://dx.doi.org/10.46646/sakh-2021-1-314-317.

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In the settlement of Gorodnaya, at the beginning of 2020, 71 patients with thyroid diseases (nodular goiter, postoperative hypothyroidism, thyrotoxicosis, hypothyroidism) were registered, including 8 patients for the first time detected in 2019. According to the 2020 study, 7 people fell ill with thyroid cancer in the village - 1 man and 6 women, which amounted to 14.3% and 85.7%, respectively. The highest incidence rates were registered among men aged 51-60 years, and among women - in the age groups 51-60 years old and 61-70 years old. At the age of 21-30 years, thyroid gland pathology was registered in one person.
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Purificação, Isaac Rêgo, Allêh Kauãn Santos Nogueira, Matheus Araújo de Souza, João Vitor Lopes Lima, Douglas Mateus Pereira Jorge, João Gustavo dos Anjos Morais Oliveira, Bianca Colacioppo Oliveira Amancio, and Luiza Lemos Pinto Castanheira. "Cerebrovascular diseases mortality in young adults in the state of São Paulo." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.415.

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Background: The incidence of Cerebrovascular Diseases (CVD) increases significantly with age, being more frequent in the elderly. For this reason, there are still few studies that describe the epidemiological profile of these pathologies in youn g adults. Methods and Objective: From the data collected prospectively and allocated on the TabNet platform (DataSUS, MS), an observational, descriptive and cross-sectional study was carried out. As a primary objective, we seek to describe the demographic information most associated with CVD mortality in individuals between 20 and 49 years old, in São Paulo. Results: The year 2011 emerged in relation to mortality, with 1,432 deaths; in the 2010- 2019 period, the average number of deaths (± standard deviation [SD]) was 1,318 (± 61), per year. In this period, the number of deaths was higher in the capital (4,605; 34.9% of the total in the state). The mean deaths (± SD), per year, in the capital and in the interior cities were, respectively: 442 (± 58) and 2.4 (± 6.2). People with schooling from 4 to 7 years old and from 8 to 11 years old were the most affected. The ratio of male deaths to female deaths was 1.05. Conclusion: There is relative stability in relation to mortality per year among young adults in the state of SP, the capital being the city with the highest number of deaths. Male individuals, with a medium level of education were responsible for most of the deaths.
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Oladejo, R. A., and B. T. Achori. "Development of a Risk-Factor Model for Predicting Occurrence of Knee Osteoarthritis." In 27th iSTEAMS-ACity-IEEE International Conference. Society for Multidisciplinary and Advanced Research Techniques - Creative Research Publishers, 2021. http://dx.doi.org/10.22624/aims/isteams-2021/v27p40.

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This study identified the required risk factors for Knee Osteoarthritis (KOA) patients and formulated a predictive model based on the identified variables. Extensive review of related work was done so as to understand the body of knowledge surrounding musculoskeletal related diseases and to identify knee osteoarthritis as one of the diseases under musculoskeletal condition as well as elicit the risk factors for it, these were validated from medical experts. The model to forecast knee osteoarthritis was formulated comparing four supervised machine learning algorithms namely Naïve Bayes, Multilayer perceptron, C4.5 Decision Tree and Support Vector Machine. The result of the model showed an accuracy of 97.59% considering the 36 initially identified attributes using no feature selection method, the results also showed the minimum number of variables relevant for knee osteoarthritis condition. Further results showed that all identified variables are relevant for effective and efficient development of a prognostic model for knee osteoarthritis. The study concluded that age as the most important variable for KOA and that all 36 identified attributes are relevant for predicting the risk of KOA. Keywords: Knee osteoarthritis, Prognostic Model, Machine learning.
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Delori, François C. "Fluorophotometer for Noninvasive Measurement of RPE Lipofuscin." In Noninvasive Assessment of the Visual System. Washington, D.C.: Optica Publishing Group, 1992. http://dx.doi.org/10.1364/navs.1992.tuc3.

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Lipofuscin is a fluorescent pigment that accumulates throughout life preferentially in the macular RPE. At old age, lipofuscin is the major constituent of the cell as it occupies most of the free cytoplasmic [1]. It has been hypothesized that cell congestion by lipofuscin affects the normal metabolic activity of the RPE [1-3], and that this process plays a role in the pathogenesis of age-related macular degeneration (AMD). Massively engorged RPE cells are found adjacent to areas where the RPE is absent secondary to atrophy in AMD [3]. Although the evidence for lipofuscin involvement in AMD is circumstantial, the possibility of quantifying lipofuscin concentration in old subjects and in patients with AMD offers the potential of a meaningful clinical evaluation of the role of lipofuscin in the development of degenerative diseases such as AMD.
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Reports on the topic "Musculoskeletal diseases in old age"

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Schat, Karel Antoni, Irit Davidson, and Dan Heller. Chicken infectious anemia virus: immunosuppression, transmission and impact on other diseases. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7695591.bard.

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1. Original Objectives. The original broad objectives of the grant were to determine A) the impact of CAV on the generation of cytotoxic T lymphocytes (CTL) to reticuloendotheliosis virus (REV) (CU), B). the interactions between chicken anemia virus (CAV) and Marek’s disease virus (MDV) with an emphasis on horizontal spread of CAV through feathers (KVI), and C) the impact of CAV infection on Salmonella typhimurium (STM) (HUJI). During the third year and the one year no cost extension the CU group included some work on the development of an antigen-antibody complex vaccine for CAV, which was partially funded by the US Poultry and Egg Association. 2. Background to the topic. CAV is a major pathogen causing clinical disease if maternal antibody-free chickens are infected vertically or horizontally between 1 and 14 days of age. Infection after 3 weeks of age when maternal antibodies are not longer present can cause severe subclinical immunosuppression affecting CTL and cytokine expression. The subclinical immunosuppression can aggravate many diseases including Marek’s disease (MD) and several bacterial infections. 3. Major conclusions and achievements. The overall project contributed in the following ways to the knowledge about CAV infection in poultry. As expected CAV infections occur frequently in Israel causing problems to the industry. To control subclinical infections vaccination may be needed and our work indicates that the development of an antigen-antibody complex vaccine is feasible. It was previously known that CAV can spread vertically and horizontally, but the exact routes of the latter had not been confirmed. Our results clearly show that CAV can be shed into the environment through feathers. A potential interaction between CAV and MD virus (MDV) in the feathers was noted which may interfere with MDV replication. It was also learned that inoculation of 7-day-old embryos causes growth retardation and lesions. The potential of CAV to cause immunosuppression was further examined using CTL responses to REV. CTL were obtained from chickens between 36 and 44 days of age with REV and CAV given at different time points. In contrast to our earlier studies, in these experiments we were unable to detect a direct impact of CAV on REV-specific CTL, perhaps because the CTL were obtained from older birds. Inoculation of CAV at one day of age decreased the IgG antibody responses to inactivated STM administered at 10 days of age. 4. Scientific and Agricultural Implications The impact of the research was especially important for the poultry industry in Israel. The producers have been educated on the importance of the disease through the many presentations. It is now well known to the stakeholders that CAV can aggravate other diseases, decrease productivity and profitability. As a consequence they monitor the antibody status of the breeders so that the maternal antibody status of the broilers is known. Also vaccination of breeder flock that remain antibody negative may become feasible further reducing the negative impact of CAV infection. Vaccination may become more important because improved biosecurity of the breeder flocks to prevent avian influenza and Salmonella may delay the onset of seroconversion for CAV by natural exposure resulting in CAV susceptible broilers lacking maternal antibodies. Scientifically, the research added important information on the horizontal spread of CAV through feathers, the interactions with Salmonella typhimurium and the demonstration that antigen-antibody complex vaccines may provide protective immunity.
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Malkinson, Mertyn, Richard Witter, and Irit Davidson. Reduction of Reticuloendotheliosis in Foundation Breeding Flocks of Chickens: A Combined Immunological and Molecular Biological Approach. United States Department of Agriculture, February 1996. http://dx.doi.org/10.32747/1996.7613026.bard.

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Reticuloendotheliosis virus (REV) is an avian retrovirus that can cause immunosuppression, growth retardation and tumors. An attempt to define the extent of the economic damage to the poultry industry that it causes is discussed in this report. In addition to losses experienced by commercial laying flocks, reduced rates of hatchability and embryo developmental disorders were demonstrable due to vertical transmission of the virus. I. Eradication of REV In this project a comprehensive national program was applied for the eradication of REV from Israeli breeding stocks by the elimination of antibody-positive birds from the breeding program. The prevention of REV-infected breeders entering Israel was also implemented by serological examination of imported day-old chickens and turkeys for maternal antibody. At the same time commercial breeding flocks in Israel were surveyed routinely to measure the extent of environmental exposure to REV throughout Israel. II. Economic factors associated with vertical transmission on breeders and progeny It was observed that on some poultry farms exposure of breeding flocks to viral infection, if it occurs when the birds are immunocompetent, leads only to a seroconvertion event. In these flocks no differences were demonstrated between the performances of seronegative and seropositive birds. When the F1 generation was selected according to seronegativity of the parents, all the progeny were seronegative, indicating that tolerantly infected birds did not form a significant proportion of the parent flock. In sharp contrast, breeding flocks that became exposed to the virus about the point of lay or during the laying period, shed virus vertically for a brief period of time through the egg. Our epizootiological observations lead us to conclude that the progeny (laying pullets) becomes tolerantly infected and are immunosuppressed as they increase in age. Increased mortality and susceptibility to intercurrent diseases were recorded.
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