Relevant bibliographies by topics / Mutols

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Mutols'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Mutols"

1

Nährlich, Stefan. "Orientierungslos, mutlos, machtlos." Blätter der Wohlfahrtspflege 154, no. 4 (2007): 151–52. http://dx.doi.org/10.5771/0340-8574-2007-4-151.

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Feng, W. Y., E. H. Lee, and J. B. Hays. "Recombinagenic processing of UV-light photoproducts in nonreplicating phage DNA by the Escherichia coli methyl-directed mismatch repair system." Genetics 129, no. 4 (December 1, 1991): 1007–20. http://dx.doi.org/10.1093/genetics/129.4.1007.

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Abstract Nonreplicating lambda phage DNA in homoimmune Escherichia coli lysogens provides a useful model system for study of processes that activate DNA for homologous recombination. We measured recombination by extracting phage DNA from infected cells, using it to transfect recA recipient cells, and scoring the frequency of recombinant infective centers. With unirradiated phage, recombinant frequencies were less than 0.1%. However, recombination could be increased over 300-fold by prior UV irradiation of the phages. The dependence of recombination on UvrA function varied greatly with UV dose. With phage irradiated to 20 J/m2, recombinant frequencies in repressed infections of uvr+ bacteria were one-fifth those in uvrA infections; with phages irradiated to 100 J/m2, frequencies in uvr+ infections were thirty times higher than in uvrA infections. Most UV-stimulated recombination in uvrA infections appeared to depend on the bacterial methyl-directed mismatch-repair system: frequencies were depressed 5-20-fold in uvrA bacteria also lacking MutH, MutL or MutS functions, and recombinant frequencies decreased with increasing GATC-adenine methylation of phage stocks. The biological activity of nonreplicating UV-irradiated phage DNA declined with time after infection of uvrA cells; this decline was photoproduct-dependent, more marked for undermethylated than overmethylated phage DNA, and depended on host MutHLS functions. In uvr+ bacteria, where the UvrABC system provided an alternative, apparently less efficient, route to recombinagenic DNA, UV-stimulated recombinant frequencies were about twice as high in mutH or mutLS as in mut+ cells, in agreement with hyper-rec mut effects previously described by others.
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Doğan, Tayfun, and Fatma Tuba Aydın. "Do Happy Children Become Happy Adults?" Journal of Humanity and Society (insan & toplum) 11, no. 1 (2021): 69–96. http://dx.doi.org/10.12658/m0437.

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Many psychological theories emphasize the significance of early childhood events. A review of the literature reveals that studies concentrate on the consequences of adverse childhood experiences on the physical and mental health of individuals. A few studies have so far examined the effects of positive childhood experiences on mental health. This research aims to investigate the relationship between positive childhood experiences and happiness. 695 adults (488 female and 207 male) participated in the study. Positive Childhood Experiences Scale served to gather the data regarding the childhood experiences, and The Oxford Happiness Questionnaire is employed to measure the happiness of the participants. According to the results of this study, a positive correlation was found between positive childhood experiences and happiness. Positive childhood experiences explain 23% of happiness and 24% of life satisfaction. In parallel to positive childhood experiences points, the happiness and life satisfaction of the participants also increases. According to the happiness level of participants, those who inform to be very happy have higher levels of positive childhood experiences in comparison to those who feel a moderate level of happiness or declare to be unhappy. The results are discussed in the context of the literature.
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HÖFLING, José Francisco, Denise M. P. SPOLIDÓRIO, Cássio Vicente PEREIRA, Edvaldo A. R. ROSA, and Daniela MOREIRA. "Presença de Streptococcus mutans e Streptococcus mutans associado a Streptococcus sobrinus em escolares de diferentes classes sócio-econômicas e sua relação com a atividade cariogênica dessas populações." Revista de Odontologia da Universidade de São Paulo 13, no. 2 (April 1999): 173–80. http://dx.doi.org/10.1590/s0103-06631999000200012.

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As espécies de estreptococos do grupo mutans mais predominantemente isoladas de amostras salivares têm sido S. mutans e S. sobrinus. A detecção desses microrganismos em escolares de diferentes classes sócio-econômicas e sua relação com a atividade cariogênica dessas populações foi estudada, em correlação com os parâmetros clínicos CPOD, CPOS, ceo e ceos. Duzentos (200) escolares pertencentes a cinco categorias sócio-econômicas foram separados em subgrupos de acordo com as espécies de microrganismos identificadas em suas amostras salivares. Do total de crianças analisadas, 103 (51,0%) apresentaram apenas S. mutans na saliva, 33 (17,0%) a associação S. mutans/S. sobrinus, e o restante, 64 (32,0%), outras espécies do grupo mutans (individualmente ou em associação). Nos subgrupos S. mutans e S. mutans/S. sobrinus 79,0% (81) e 76,0% (25), respectivamente, apresentavam cárie dentária, sugerindo um alto índice cariogênico. Para os indivíduos colonizados por S. mutans/S. sobrinus e apenas S. mutans, obtiveram-se valores médios de 9,40 e 6,70, respectivamente, para o índice de ceos, sugerindo que a associação S. mutans/S. sobrinus é potencialmente mais cariogênica que a colonização apenas por S. mutans.
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Singh, Paramdeep, Avninder Kaur, Neerja Kakkar, Manjeet Kaur, and Shivesh Acharya. "Quantitative Correlation of Salivary Streptococcus Mutans Count Amongst Siblings and their Mothers." Dental Journal of Advance Studies 05, no. 02 (August 2017): 090–96. http://dx.doi.org/10.1055/s-0038-1672089.

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Abstract Aim: The present study was planned to analyze quantitative correlation of salivary Streptococcus Mutans (S. Mutans) in siblings and their mothers. Materials and Methods: Quantitative analysis of S. Mutans in saliva was performed using Dentocult SM strip mutans kit (Orion Diagnostica, Helsinki, Finland) in closely related members of the family i.e. siblings along with their mothers. Results: S. Mutans count between the siblings showed positive correlation which was statistically highly significant. The younger childrens’ S. Mutans count was very highly correlated (rs = 0.711) with the mothers’ as compared to that of the older children (rs = 0.412). The S. Mutans count was found to be associated with caries score and was statistically significant. A statistically highly significant positive association was also found with the plaque score. Conclusion: The correlation between the S. Mutans count of related individuals has been reaffirmed. S. Mutans is positively associated with dental caries.
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Zeng, Y., M. Youssef, L. Wang, N. Alkhars, M. Thomas, R. Cacciato, S. Qing, O. Ly-Mapes, and J. Xiao. "Identification of Non-Streptococcus mutans Bacteria from Predente Infant Saliva Grown on Mitis-Salivarius-Bacitracin Agar." Journal of Clinical Pediatric Dentistry 44, no. 1 (January 1, 2020): 28–34. http://dx.doi.org/10.17796/1053-4625-44.1.5.

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Objective: Although mitis-salivarius-bacitracin (MSB) agar is a commonly used selective medium for detecting Streptococcus mutans in clinical studies, non-S. mutans microorganisms are cultivatable on MSB agar. Since few studies have identified non-S. mutans bacteria grown on MSB, this study aimed to identify and differentiate MSB-grown non-S. mutans bacteria from predente infants' oral cavity. Study design: The saliva from 51 predente infants were plated on MSB agars. Bacteria colonies were characterized based on their morphology under direct visualization and light microscopic observation. Colony PCR targeting S. mutans htrA locus and 16S rRNA DNA sequencing were used for further bacteria identification. Results: Overall, 80% of the predente infants had oral bacteria grown on the MSB agar. Nine bacteria were identified, including S. mutans, Staphylococcus epidermidis, Klebsiella quasi-pneumoniae, Klebsiella pneumoniae, Enterobacter kobei, Enterococcus faecalis, Staphylococcus hominis, Streptococcus anginosus and Phytobacter. The most frequently detected bacteria were S. epidermidis (41.5%), followed by E. kobei (24.4%), K. pneumoniae (17.1%) and S. mutans (9.8%.) Conclusions: Multiple non-S. mutans bacteria from infants' oral cavity could grow on MSB agar. Caution should be exercised in counting the colony forming units of S. mutans from oral samples on MSB agar to avoid overestimation by assuming that all colonies on the MSB agar are S. mutans. Using the colony morphological guide we summarized, these non-S. mutans bacteria could be distinguished from S. mutans. Our study provides a key reference to pediatric cariology clinical-epidemiological studies that commonly use MSB to identify/quantify S. mutans in infants and young children.
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Ong, Seung-Hwan, Jongsoo Kim, Dong-Heon Baek, and Seunghoon Yoo. "Comparison of Cariogenic Characteristics between Fluoride-sensitive and Fluoride-resistant Streptococcus mutans." JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY 47, no. 4 (November 30, 2020): 397–405. http://dx.doi.org/10.5933/jkapd.2020.47.4.397.

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The aim of this study is to compare cariogenic characteristics of fluoride-sensitive <i>Streptococcus mutans</i> [fluoride-sensitive (FS) <i>S. mutans</i> ] and fluoride-resistant <i>Streptococcus mutans</i> [fluoride-resistant (FR) <i>S. mutans</i>] in the presence of sucrose, and to evaluate its effect on cariogenic biofilm formation. <i>S. mutans</i> ATCC 25175 was continuously cultured in trypticase soy broth (TSB) containing NaF (70 ppm) for 40 days to generate FR <i>S. mutans</i> . FS and FR <i>S. mutans</i> were inoculated in TSB with or without 2% sucrose, and optical density and pH were measured every hour. An oral biofilm was formed using saliva bacteria and analyzed through confocal laser scanning microscopy and CFU count. Finally, the expression of glucosyltransferases genes of both <i>S. mutans</i> was investigated through RT-PCR. FR <i>S. mutans</i> exhibited slower growth and lower acidogenicity in the presence of sucrose compared to FS <i>S. mutans</i> . Both cariogenic and single species biofilm formation was lower in the presence of FR <i>S. mutans</i> , along with reduced number of bacteria. FR <i>S. mutans</i> showed significantly low levels of gtfB, gtfC, and gtfD expression compared to FS <i>S. mutans</i> . On the basis of results, FR <i>S. mutans</i> may be less virulent in the induction of dental caries.
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Alves, Alessandra C., Ruchele D. Nogueira, Rafael N. Stipp, Flávia Pampolini, Antonio B. A. Moraes, Reginaldo B. Gonçalves, José F. Höfling, Yihong Li, and Renata O. Mattos-Graner. "Prospective study of potential sources of Streptococcus mutans transmission in nursery school children." Journal of Medical Microbiology 58, no. 4 (April 1, 2009): 476–81. http://dx.doi.org/10.1099/jmm.0.005777-0.

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Transmission of Streptococcus mutans, a major dental caries pathogen, occurs mainly during the first 2.5 years of age. Children appear to acquire S. mutans mostly from their mothers, but few studies have investigated non-familial sources of S. mutans transmission. This study prospectively analysed initial S. mutans oral colonization in 119 children from nursery schools during a 1.5-year period and tracked the transmission from child to child, day-care caregiver to child and mother to child. Children were examined at baseline, when they were 5–13 months of age, and at 6-month intervals for determination of oral levels of S. mutans and development of caries lesions. Levels of S. mutans were also determined in caregivers and mothers. A total of 1392 S. mutans isolates (obtained from children, caregivers and mothers) were genotyped by arbitrarily primed PCR and chromosomal RFLP. Overall, 40.3 % of children were detectably colonized during the study, and levels of S. mutans were significantly associated with the development of caries lesions. Identical S. mutans genotypes were found in four nursery cohorts. No familial relationship existed in three of these cohorts, indicating horizontal transmission. Despite high oral levels of S. mutans identified in most of the caregivers, none of their genotypes matched those identified in the respective children. Only 50 % of children with high levels of S. mutans carried genotypes identified in their mothers. The results support previous evidence indicating that non-familial sources of S. mutans transmission exist, and indicate that this bacterium may be transmitted horizontally between children during the initial phases of S. mutans colonization in nursery environments.
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Wang, Bing-Yan, and Howard K. Kuramitsu. "Interactions between Oral Bacteria: Inhibition of Streptococcus mutans Bacteriocin Production by Streptococcus gordonii." Applied and Environmental Microbiology 71, no. 1 (January 2005): 354–62. http://dx.doi.org/10.1128/aem.71.1.354-362.2005.

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ABSTRACT Streptococcus mutans has been recognized as an important etiological agent in human dental caries. Some strains of S. mutans also produce bacteriocins. In this study, we sought to demonstrate that bacteriocin production by S. mutans strains GS5 and BM71 was mediated by quorum sensing, which is dependent on a competence-stimulating peptide (CSP) signaling system encoded by the com genes. We also demonstrated that interactions with some other oral streptococci interfered with S. mutans bacteriocin production both in broth and in biofilms. The inhibition of S. mutans bacteriocin production by oral bacteria was stronger in biofilms than in broth. Using transposon Tn916 mutagenesis, we identified a gene (sgc; named for Streptococcus gordonii challisin) responsible for the inhibition of S. mutans bacteriocin production by S. gordonii Challis. Interruption of the sgc gene in S. gordonii Challis resulted in attenuated inhibition of S. mutans bacteriocin production. The supernatant fluids from the sgc mutant did not inactivate the exogenous S. mutans CSP as did those from the parent strain Challis. S. gordonii Challis did not inactivate bacteriocin produced by S. mutans GS5. Because S. mutans uses quorum sensing to regulate virulence, strategies designed to interfere with these signaling systems may have broad applicability for biological control of this caries-causing organism.
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Minasari, Minasari, Sri Amelia, and Nevi Tinambunan. "PERBEDAAN EFEK EKSTRAK BAWANG MERAH TERHADAP PERTUMBUHAN Streptococcus mutans DARI KARIES DAN Streptococcus mutans (ATCC® 35668™)." Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) 10, no. 3 (November 5, 2018): 296–300. http://dx.doi.org/10.36911/pannmed.v10i3.144.

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Bawang merah merupakan tanaman herbal yang biasa digunakan sebagai bumbu masakan yang memiliki efek antibakteri karena adanya kandungan alkaloid, saponin, dan flavonoid. Alkaloid berfungsi dalam menghambat sintesis protein dan asam nukleat, saponin berperan dalam merusak permeabilitas membran sel, dan flavonoid berfungsi dalam menghancurkan dinding sel Streptococcus mutans. Streptococcus mutans adalah bakteri dominan terjadinya karies. Penelitian ini bertujuan untuk mengetahui efek ekstrak bawang merah terhadap pertumbuhan Streptococcus mutans dari karies dan Streptococcus mutans (ATCC® 35668™), serta untuk mengetahui perbedaan efek ekstrak bawang merah terhadap kedua jenis bakteri tersebut. Penelitian ini merupakan penelitian eksperimental laboratoris dengan rancangan posttest control group design. Sampel yang digunakan adalah biakan Streptococcus mutans yang diisolasi dari pasien karies dan Streptococcus mutans (ATCC® 35668™). Ekstrak bawang merah dilakukan dengan metode dilusi untuk mendapatkan berbagai konsentrasi ekstrak 80%, 40%, 20%, 10%, 5%, 2,5%, dan 1,25% kemudian ditambahkan suspensi bakteri pada setiap konsentrasi. Analisis data yang digunakan adalah uji deskriptif frekuensi yaitu median untuk mendapatkan nilai tengah dari konsentrasi KHM dan KBM yang dilakukan dengan tiga kali pengulangan dan uji statistik Mann Whitney yang digunakan untuk mencari apakah terdapat perbedaan yang signifikan antara konsentrasi KHM dan KBM bakteri Streptocccus mutans dari karies dan Streptococcus mutans (ATCC® 35668™). Hasil penelitian ini diperoleh konsentrasi KHM dan KBM dari ekstrak bawang merah terhadap pertumbuhan bakteri Streptococcus mutans yang diisolasi dari pasien karies masing-masing 40% dan 80%. Adapun nilai KHM dan KBM dari ekstrak bawang merah terhadap pertumbuhan Streptococcus mutans (ATCC® 35668™) masing-masing 20% dan 40%. Hasil uji Mann Whitney menunjukkan tidak terdapat perbedaan efek yang signifikan (p>0,05) antara nilai KHM dan KBM dari ekstrak bawang merah terhadap kedua jenis Streptococcus mutans. Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa ekstrak bawang merah memiliki efektivitas terhadap pertumbuhan Streptococcus mutans dari karies dan Streptococcus mutans (ATCC® 35668™).
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Dissertations / Theses on the topic "Mutols"

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Mauris, Jérôme. "Aquifex aeolicus MutS and MutL : insights into the mismatch repair in a hyperthermophilic bacterium." Paris 11, 2009. http://www.theses.fr/2009PA112309.

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La comparaison du génome des bactéries methylant les sites GATC de l’ADN avec celui des bactéries et des eucaryotes ne methylant pas leur ADN aux sites Dam montre que ces derniers n’ont pas d’homologue de MutH, une endonuclease impliquée dans la réparation des mésappariements de bases de l’ADN. Ceci implique une discrimination entre le brin parental et le brin fils, lors de la réplication. Nous avons montré que MutL, chez la bactérie thermophile Aquifex aeolicus (Aae), est comparable à MutLalpha chez les eucaryotes. In vitro, Aae MutL a une activité endonucléase en présence de métaux lourds, stimulée par l’ATP et ne nécessitant par son hydrolyse en ADP. De plus, cette activité est confinée dans le domaine C-terminale de la proteine, dont nous avons caractérisé un motif propre à la famille de répresseurs à la toxine diphtérique (DtxR) et un second motif n’appartenant à aucune famille de protéines connue à ce jour, tous deux impliqués dans l’activité nucléase de Aae MutL. AaeMutL est donc un homologue de la protéine humaine PMS2. Nous avons également caractérisé la protéine Aq_793 et confirmé son activité helicase ATP-dépendente thermostable, qui préfère les substrats ayant une extrémité simple-brin protubérante en 3’, comme UvrD chez E. Coli. Aae MutL est capable de stimuler cette activité avec seulement ce substrat. Cette activation n’est pas dépendante de l’activité endonucléase de MutL. De plus, le domaine C-terminal seul est capable d’activer l’activité hélicase d’Aq_793, phénomène qui n’est pas observé chez E. Coli. Nous avons montré que le système de réparation des mésappariements chez Aquifex aeolicus a des similitudes avec celui d’E. Coli et des eucaryotes
The mismatch repair (MMR) pathway ensures the stability of the genome by correcting the replicative error. In Esherichia coli, MutH discriminates the neosynthetized strand from the template via the hemimethylated GATC (Dam) site. By comparison, eukaryotes and bacteria unable to perform dam methylation do not exibit MutH homologs implying a different method of recognition of the DNA in the MMR pathway. We have shown that MutL from Aquifex aeolicus, a hyperthermophilic bacterium, is similar to eukaryotic MutLalpha. In vitro, Aae MutL is an endonuclease in the presence of heavy metals. This activity is stimulated by ATP binding but not ATP hydrolysis. We also were able to demonstrate that the C-terminal domain (CTD) of MutL was sufficient for MutL endonuclease activity with the characterization of two motifs, the heavy metal binding domain (DtxR) and a yet unknown domain responsible for this activity. Thus, Aae MutL is homologous to human PMS2. We also caracterized the putative helicase Aq_793 and confirmed that the ATP-dependent helicase has a strong preference for a 3’tail ssDNA substrate such as E. Coli UvrD. Moreover, Aae MutL is able to stimulate Aq_793 helicase activity only for this type of substrate in an endonuclease independent fashion. Interestingly, the CTD of Aae MutL was able to stimulate the helicase as well, a phenomenon not observed in E. Coli. We have shown that Aquifex aeolicus MMR pathway has similarities with both E. Coli and eukaryotes
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Mendillo, Marc Laurence. "The MutS and MutL protein families and their role in the initiation of DNA mismatch repair." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3273476.

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Thesis (Ph. D.)--University of California, San Diego, 2007.
Title from first page of PDF file (viewed April 9, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Müller, Dell'Oro Magdalena, and Salas Macarena Rodríguez. "Análisis de la inversión de los fondos mutuos : fondos mutuos de capitalización nacional." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/135393.

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Seminario para optar al título de Ingeniero Comercial, Mención Administración y Mención Economía
En el presente estudio se realiza un análisis de la selección de cartera de los Fondos Mutuos, particularmente del mercado accionario nacional. El objetivo de este análisis es determinar si la distribución de carteras está relacionada con la situación de mercado actual y a la vez, si ésta asignación de los Fondos Mutuos es eficiente. Las alocaciones y rentabilidad de los Fondos Mutuos de capitalización nacional a lo largo del periodo estudiado nos permitirán tener una visión de cómo se relaciona la selección de carteras con las distintas situaciones de mercado. A lo anterior se suman distintas medidas de eficiencia, como lo son el Alpha de Jensen y Ratio de Sharpe, lo cual agregará profundidad al estudio. Los principales resultados indican que a nivel general la selección de cartera si está relacionada con la situación de mercado actual. Con respecto a la eficiencia los antecedentes estudiados nos permiten concluir que las administradoras si gestionan eficientemente sus carteras en relación a su benchmark. Este análisis es realizado a nivel general de la cartera de los Fondos Mutuos, no debemos olvidar que dentro de esta industria cada uno de los fondos tiene una política de inversión particular. Por otro lado la base de datos utilizada no considera costos de administración.
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Lewis, Christopher Roger. "Chromosomal deletions in Streptococcus mutans." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297569.

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Camarena, Rodríguez Martín Eulogio. "Los fondos mutuos de inversión." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2011. https://hdl.handle.net/20.500.12672/15109.

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Publicación a texto completo no autorizada por el autor
El primer capítulo, la tesis permite tener una mirada mirada rápida a los aspectos generales de los mercados de valores, del mercado de valores en el Perú y el papel de este frente a la globalización. El segundo capítulo se centra en el tema propiamente dicho: el concepto y clasificación de los mismos, conjuntamente con sus inversiones, composición y valor de la cuota, igualmente el entorno económico en la evolución de los mismos; el papel del Estado en la defensa de los ciudadanos; la visión que aporta la legislación comparada. En el tercer capítulo se analiza el papel de los mismos en el mercado de valores, así como el impacto de los mismos en los mercados de valores mundiales y nacionales. En el cuarto capítulo los sistemas de fondos mutuos y su operatividad, observaremos la situación de los fondos mutuos que operan en el Perú, su constitución y situación actual, su nivel de operatividad: funcionamiento y rendimiento, los fondos mutuos respecto de otros mecanismos de inversión, la naturaleza jurídica de los certificados de participación. En el capítulo quinto se reflexiona acerca del tema de la calidad de los fondos mutuos como medios de representación del capital. En el capítulo sexto se analiza la ley del mercado de valores y de su reglamento respectivo conjuntamente con las perspectivas de reforma de la ley. En el capítulo séptimo se analiza a los fondos mutuos como una alternativa de financiamiento para la pequeña y microempresa en un país como el Perú donde lo que abunda paradójicamente es el dinero, pero faltan aquellos instrumentos en donde se puedan invertir.
Tesis
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Thevenot, Tracy Lynn. "Aspects of sugar transport via the phosphoenolpyruvate sugar phosphotransferase system of streptococcus mutans /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23673.pdf.

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Monteiro-Oliveira, Marcela Pinto 1982. "Estudo da ação antimicrobiana da terapia fotodinamica sobre lesões de carie produzidas in vitro na dentina de dentes bovinos." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288089.

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Orientador: Marines Nobre dos Santos Uchoa
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Durante o processo conhecido como terapia fotodinâmica, a aplicação de fotossensibilizadores associados a uma fonte de luz de comprimento de onda complementar, gera produtos que podem danificar componentes essenciais das células, e causar a morte celular. Dentro desse contexto, a aplicação dessa terapia sobre microrganismos presentes em lesões de cárie é de grande valia, uma vez que poderá reduzir a quantidade de tecido dental a ser removido no tratamento da cárie, diminuir as chances de progressão da doença bem como os riscos de acometimento pulpar do elemento dentário. Assim, o objetivo deste estudo in vitro foi determinar parâmetros para o uso de um diodo emissor de luz (LED) associado ao corante azul de orto toluidina (TBO) na redução da contagem de Streptococcus mutans presentes em lesões de cárie dentinária. Para isto, 72 espécimes de dentina coronária de dentes bovinos foram imersos em cultura contendo Streptococcus mutans para produzir lesões de cárie. Tais espécimes foram divididos aleatoriamente em 6 grupos (n=12): Controle (exposição a NaCl a 0,9% por 5 min); TBO (exposição ao TBO a 0,01% por 5 min); LEDA (exposição ao LED por 4,2 min); LEDB (exposição ao LED por 6,5 min); PDTA (exposição ao corante associado ao LED por 4,2 min) e PDTB (exposição ao corante associado ao LED por 6,5 min). As densidades de energia utilizadas para os tempos de 4,2 e 6,5 min, foram de 166 e 249 J/cm2, respectivamente. Antes e após os tratamentos, amostras de tecido dentinário cariado foram coletadas e analisadas microbiologicamente, por meio da contagem das unidades formadoras de colônia (UFC) de S. mutans. A profundidade das lesões de cárie produzidas pelo modelo microbiológico utilizado foi determinada por meio da microscopia de luz polarizada. Foram utilizados os testes ANOVA/Tukey para comparar os valores de log redução dos grupos (a=5%). Observou-se redução significativa de S. mutans nos grupos em que aplicou-se TBO associado ao LED, com as duas densidades de energia utilizadas. Entretanto, nenhuma diferença significativa foi encontrada para os diferentes tempos de irradiação. Concluiu-se que os parâmetros utilizados no presente estudo, para o emprego do LED associado ao TBO, foram efetivos em reduzir a contagem de S. mutans presentes em lesões de cárie dentinária.
Abstract: Photodynamic therapy (PDT) is a technique that consists in the activation of certain photosensitizers by light in the presence of tissue oxygen, resulting in the production of reactive radicals capable of inducing cell death. In this context, this therapy may become a suitable approach to disinfect the dentin tissue during the caries treatment, and reduce the tissue removal, minimizing the probability of caries progression and pulp involvement. This randomized in vitro study determined parameters for using a light-emitting diode (LED) with toluidine blue O (TBO) for reduction of Streptococcus mutans counts inside dentin caries. Seventy two bovine coronary dentin slabs were immersed in Streptococcus mutans culture for demineralization production. Dentin slabs were allocated to 6 groups (n=12) as follows: Control (treated with 0.9% NaCl solution for 5 min); TBO (treated with 0.1 mg/ml TBO for 5 min); LEDA (submitted to irradiation for 4.2 min); LEDB (submitted to irradiation for 6.5 min); PDTA (treated with TBO plus irradiation for 4.2 min) and PDTB (treated with TBO plus irradiation for 6.5 min). The energy densities used for 4.2 and 6.5 min correspond at 166 and 249 J/cm2, respectively. Before and after treatments, dentin samples were analyzed with regard to S. mutans counts. The caries lesion depth produced by the microbiological model was analyzed by polarized light microscopy. ANOVA/Tukey tests were utilized to compare log reductions among groups (a=5%). Bacterial reduction was observed when dentin was exposed to both TBO and LED at both irradiation times. However, no difference in S. mutans reduction was found between the two energy densities. Concluding, although the use of LED combined with TBO was effective in reducing the Streptococcus mutans counts in carious dentin, this effect may not have clinical significance.
Mestrado
Odontopediatria
Mestre em Odontologia
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Vizoto, Natália Leal 1982. "Avaliação da função biológica do sistema de dois componentes SptRS de Streptococcus mutans." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288675.

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Orientador: Renata de Oliveira Mattos-Graner
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Streptococcus mutans é uma espécie bacteriana comum da microbiota bucal de seres humanos envolvida na patogênese da cárie dentária e em endocardites infecciosas promovidas por bacteremias de origem bucal. Para ser transmitido e ocupar seus nichos ecológicos, S. mutans precisa persistir na saliva e se adaptar fisiologicamente a cada fase da colonização, um processo que provavelmente envolve diversas alterações do seu transcriptoma. Para isto, S. mutans utiliza sistemas reguladores de transcrição de dois componentes (SDC). O SDC SptRS foi identificado através de análises in silico do genoma da cepa S. mutans UA159, como ortólogo do sistema SptSR (Spt de Saliva persistence) de Streptococcus pyogenes. O objetivo deste trabalho foi investigar a participação do sistema SptRS de S. mutans em fenótipos importantes para a colonização bucal. Para isto, mutantes knockout dos genes sptR e sptS, SMU.927 e SMU.928 respectivamente, foram construídos a partir da cepa UA159 (UAsptR- e UAsptS-) e comparados com a cepa parental em análises de morfologia, crescimento planctônico sob diferentes condições nutricionais, persistência em saliva humana, formação de biofilme e autólise a 44oC. Além disto, genes do regulon de SptRS foram pesquisados através de ensaios da Imunoprecipitacão de Cromatina seguido de sequenciamento (ChIP-seq), RT-PCR quantitativo (RT-PCRq) e de Ensaios de Retardamento da Mobilidade Eletroforética (EMSA) com proteína recombinante SptRr de S. mutans. Os mutantes sptR e sptS mostraram crescimento planctônico lento em meios de cultura RPMI e em MQD comparados à cepa parental, além de atividade autolítica reduzida em 22,4 e 53,13%, respectivamente. Não foram observadas, entretanto, alterações significativas na morfogênese, formação de biofilmes in vitro, nem na persistência em saliva humana. Os dados de ChIP-seq e RT-qPCR indicaram que SptRS regula genes envolvidos na resposta de estringência (SMU.926), repressão catabólica (ccpA), metabolismo de múltiplos açúcares (SMU.78, SMU.137, SMU.542, SMU.1734), sistemas fosfoenolpiruvato-fosfotransferase (PTS) (SMU.2047, SMU.114, SMU.115) sistemas de transporte do tipo ABC (SMU.182, SMU.880, SMU.905, SMU.1035, SMU.1095, SMU.1178c, SMU.1939) e biogênese de parede celular (SMU.1091, SMU.2147, SMU.609, SMU.1434c, SMU.22). SptR funcionou como um regulador negativo em 86% (37/43) dos genes testados. Análises de RT-qPCR e EMSA indicaram ainda que SptR regula diretamente o regulador de transcrição CovR (SMU.1924), envolvido na repressão de genes de virulência e formação de biofilmes. Este estudo fornece evidências de que SptRS regula diversas funções de S. mutans importantes para a sobrevivência em condições nutricionalmente escassos, aparentemente coordenando o metabolismo com o crescimento bacteriano e com a expressão de genes de virulência
Abstract: Streptococcus mutans is a common bacterial species of the bucal microbiota of humans involved in the pathogenesis of dental caries and infectious endocarditis promoted by bacteremia of bucal origin. To be transmitted and occupy their ecological niches, S. mutans need to persist in saliva and adapt physiologically to each phase of colonization, a process that probably involves several changes in its transcriptome. To this end, S. mutans uses transcriptional regulatory systems called Two Component System (TCS). The TCS SptRS was identified in an in silico analysis of the genome of S. mutans strain UA159, as an orthologue of the SptRS system (Spt of Saliva persistence) of Streptococcus pyogenes. The aim of this study was to investigate the role of the TCS SptRS in functional traits important for S. mutans to colonize its bucal niches. Thus, knockout mutants of sptR and sptS (SMU.927 and SMU.928, respectively) were obtained in strain UA159 (UAsptR-, UAsptS-) and compared to parental strain regarding morphology, planktonic growth under different nutritional conditions and persistence in human saliva, biofilm formation and autolysis at 44oC. In addition, genes of SptRS regulon were analised by Chromatin Immunoprecipitation followed the sequencing (ChIP-seq), quantitative RT-PCR (RT- qPCR) and Electrophoretic Mobility Shift Assays (EMSA) with S. mutans SptR recombinant protein. Inactivation of sptR/S promotes slow planktonic growth in RPMI and CDM, culture media 22.4 to 53.13% reductions in autolysis respectively, but does not significantly affect morphogenesis. However, mutants do not show significant alterations in biofilm formation or in persistence in human saliva. ChIP-seq and RT-qPCR analyses showed that SptRS regulates genes for stringent response (SMU.926), metabolism of multiple sugars (SMU.78, SMU.137, SMU.542, SMU.1734), catabolite repression (SMU.1591, ccpA), phosphoenolpyruvate phosphotransferase systems (PTS), ABC transport systems (SMU.182, SMU.880, SMU.905, SMU.1035, SMU.1095, SMU.1178c, SMU.1939) and cell wall biogenesis (SMU.22, SMU.609, SMU.1091, SMU.1434c, SMU.2147) SptR worked as a negative regulator of 86% (37/43) of the tested genes. RT-qPCR and EMSA analyses further showed that SptR directly represses expression of the transcriptional regulator CovR (SMU.1924), which is a repressor of genes involved in biofilm formation and virulence. This study provides evidence that SptRS regulates several functions important for S. mutans survival under poor nutritional conditions, apparently coordinating metabolism with bacterial growth and expression of virulence genes
Doutorado
Microbiologia e Imunologia
Doutora em Biologia Buco-Dental
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Aravena, Solís Franco. "Persistencia en rentabilidad de fondos mutuos : evidencia para el mercado chileno de fondos mutuos accionarios." Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/145640.

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TESIS PARA OPTAR AL GRADO DE MAGÍSTER EN FINANZAS
Hoy en día en Chile existen una serie de instrumentos de inversión disponibles para una amplia diversidad de inversionistas, dentro de los que se encuentran depósitos a plazo, acciones y fondos mutuos, entes otros, siendo este último uno de los más populares debido a que cualquier persona que tiene ahorros, puede dirigirse a una administradora general de fondos (de aquí en adelante AGF), e invertir sin necesariamente tener conocimiento o expertise en este mercado. Dado esta popularidad surge la necesidad de entender si efectivamente este instrumento es una buena alternativa para alguien no especialista en inversiones, y con ello ahondar en si este resultado es el mismo indistinto de la AGF. Los fondos mutuos han tenido un alto crecimiento y desarrollo las últimas décadas. En las Figuras 1 y 2 a continuación, se puede ver que si bien el número de sociedades administradoras, sólo aumentó de 13 a 18, desde 2000 a junio de 2016, la cantidad de fondos administrados, aumentó casi cinco veces en este mismo período pasando de ser 124 a 501 fondos. Asimismo, en la Figura 2, se puede ver que el patrimonio administrado, y el número de partícipes, han crecido de forma abrupta desde el año 2000, presentando dos años (2010 y 2014) con crecimiento en el patrimonio anual que destacan por sobre la tendencia al alza sostenida que muestra este mercado. De esta forma, el mercado ha llegado a tener más de dos millones de partícipes, así como también, un patrimonio, de más de 28 billones de pesos, que es cercano a un 18,5%1 del PIB nacional a diciembre de 2016. Cabe destacar que, dentro de los partícipes, se consideran tanto las personas naturales, como las jurídicas.
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Gangloff, Sophie. "Les adhesines des bacteries du groupe mutans : cartographie antigenique d'une proteine de surface de streptococcus mutans." Strasbourg 1, 1991. http://www.theses.fr/1991STR15070.

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Books on the topic "Mutols"

1

Tola, Ciriaco Antonio. Cantones e mutos. Cagliari: AM&D, 1997.

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Maria de Lurdes Mutola. Mozambique?: publisher not identified, 2008.

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Réveils mutins. Montréal: Les Intouchables, 1998.

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Mutoko madness. Harare, Zimbabwe: Boundary Books, 2013.

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Hetherington, J. A. C. Why mutuals? Toronto: Law and Economics Programme, Faculty of Law, University of Toronto, 1990.

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Allison, William. Les mutins. [Paris?]: A.M.M.E. Editions, 1990.

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McCauley, Barbara. Muthis cekim. Istanbul: Harlequin, 1994.

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Lévesque, Jocelyne. Le temps mutilé. Saint-Lambert, Québec: Éditions du Noroît, 1991.

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Paris mutuels: Roman. Paris: Éditions La Branche, 2012.

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Parenteau, François. Réveils mutins II. Outremont, Québec: Lanctôt éditeur, 2000.

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Book chapters on the topic "Mutols"

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Meineck, Peter. "Muthos." In Theatrocracy, 30–51. Abingdon, Oxon ; New York : Routledge, 2017.: Routledge, 2017. http://dx.doi.org/10.4324/9781315466576-2.

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Spain, Don. "Mutus." In The Six-Inch Lunar Atlas, 83–86. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-87610-8_20.

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Wild, Gerhard. "Mutis, Álvaro." In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_13320-1.

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Lemos, J. A., S. R. Palmer, L. Zeng, Z. T. Wen, J. K. Kajfasz, I. A. Freires, J. Abranches, and L. J. Brady. "The Biology of Streptococcus mutans." In Gram-Positive Pathogens, 435–48. Washington, DC, USA: ASM Press, 2019. http://dx.doi.org/10.1128/9781683670131.ch27.

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Lewis, C. R., and R. R. B. Russell. "Chromosomal Deletions in Streptococcus mutans." In Streptococci and the Host, 677–79. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4899-1825-3_158.

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Nakano, Kazuhiko, Ichiro Nakagawa, Satu Alaluusua, and Takashi Ooshima. "Molecular Typing of Streptococcus mutans." In Molecular Typing in Bacterial Infections, 127–47. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-185-1_9.

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Hoffmann, Kai. "Die Logik des Mutes." In Dein Mutmacher bist du selbst!, 89–96. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-30989-3_15.

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Hoffmann, Kai. "Die Logik des Mutes." In Dein Mutmacher bist du selbst!, 107–14. Wiesbaden: Springer Fachmedien Wiesbaden, 2013. http://dx.doi.org/10.1007/978-3-8349-3697-4_16.

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Hoffmann, Kai. "Die Logik des Mutes." In Dein Mutmacher bist du selbst!, 107–14. Wiesbaden: Gabler Verlag, 2009. http://dx.doi.org/10.1007/978-3-8349-4410-8_16.

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Lion, Christine, A. Lozniewski, M. Weissenbach, and M. Weber. "“Streptococcus mutans” Group in Human Saliva." In Streptococci and the Host, 173–75. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4899-1825-3_42.

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Conference papers on the topic "Mutols"

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Sadler, Jonathan. "Mutli-Layer Traffic Engineering." In National Fiber Optic Engineers Conference. Washington, D.C.: OSA, 2010. http://dx.doi.org/10.1364/nfoec.2010.nthe1.

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Lohmann, Steffen, Paloma Díaz, and Ignacio Aedo. "MUTO." In the 7th International Conference. New York, New York, USA: ACM Press, 2011. http://dx.doi.org/10.1145/2063518.2063531.

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Aadit, Thanekar, Jha Deepak, Patil Janhavi, and Deone Jyoti. "Video Chat Application for Mutes." In 2021 International Conference on Emerging Smart Computing and Informatics (ESCI). IEEE, 2021. http://dx.doi.org/10.1109/esci50559.2021.9397044.

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Beier, Brooke D., Robert G. Quivey, and Andrew J. Berger. "Confocal Raman Microspectroscopy of Streptococcus sanguis and mutans." In Frontiers in Optics. Washington, D.C.: OSA, 2010. http://dx.doi.org/10.1364/fio.2010.ftuf7.

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Beier, Brooke D., Robert G. Quivey, and Andrew J. Berger. "Confocal Raman Microscopy of Streptococcus Sanguis and Mutans." In Frontiers in Optics. Washington, D.C.: OSA, 2008. http://dx.doi.org/10.1364/fio.2008.fwd6.

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Rago, I., A. Bregnocchi, E. Zanni, A. G. D'Aloia, F. De Angelis, M. Bossu, G. De Bellis, A. Polimeni, D. Uccelletti, and M. S. Sarto. "Antimicrobial activity of graphene nanoplatelets against Streptococcus mutans." In 2015 IEEE 15th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2015. http://dx.doi.org/10.1109/nano.2015.7388945.

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Rodríguez-Baquero, Diego, and Mario Linares-Vásquez. "Mutode: generic JavaScript and Node.js mutation testing tool." In ISSTA '18: International Symposium on Software Testing and Analysis. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3213846.3229504.

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Kallel, Omar, Ines Ben Jaafar, Lionel Dupont, and Khaled Ghedira. "Mutli-agent negotiation of fair contracts." In Industrial Engineering (CIE-40). IEEE, 2010. http://dx.doi.org/10.1109/iccie.2010.5668295.

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Shao, Yunfeng, Robert Wang, Yun Kai Deng, Xinlin Li, Gang Liu, and Runpu Chen. "Building reconstruction by mutil-baseline SAR." In 2013 IEEE Radar Conference (RadarCon). IEEE, 2013. http://dx.doi.org/10.1109/radar.2013.6586108.

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Huda, Syeda Bintul, and Nighat Noureen. "MTBGD: Mutli Type Biclustering for Genomic Data." In 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2016. http://dx.doi.org/10.1109/bibm.2016.7822677.

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Reports on the topic "Mutols"

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Born, Patricia, William Gentry, W. Kip Viscusi, and Richard Zeckhauser. Organizational Form and Insurance Company Performance: Stocks versus Mutuals. Cambridge, MA: National Bureau of Economic Research, September 1995. http://dx.doi.org/10.3386/w5246.

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Davis, Chelsea S., Jeremiah W. Woodcock, and Jeffrey W. Gilman. Preparation of Nanoscale Mutli-walled Carbon Nanotube Dispersions in a Polyetheramine Epoxy for Eco-Toxicological Assessment. National Institute of Standards and Technology, March 2015. http://dx.doi.org/10.6028/nist.sp.1200-9.

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Buckley, Patricia E., James J. Valdes, and Kevin P. O'Connell. Construction and Analysis of a MutL Knockout Strain of Vibrio cholerae. Fort Belvoir, VA: Defense Technical Information Center, October 2007. http://dx.doi.org/10.21236/ada473545.

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Gehlhaus, Diana, and Santiago Mutis. The U.S. AI Workforce: Understanding the Supply of AI Talent. Center for Security and Emerging Technology, January 2021. http://dx.doi.org/10.51593/20200068.

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As the United States seeks to maintain a competitive edge in artificial intelligence, the strength of its AI workforce will be of paramount importance. In order to understand the current state of the domestic AI workforce, Diana Gehlhaus and Santiago Mutis define the AI workforce and offer a preliminary assessment of its size, composition, and key characteristics. Among their findings: The domestic supply of AI talent consisted of an estimated 14 million workers (or about 9% of total U.S. employment) as of 2018.
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