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1

Nährlich, Stefan. "Orientierungslos, mutlos, machtlos." Blätter der Wohlfahrtspflege 154, no. 4 (2007): 151–52. http://dx.doi.org/10.5771/0340-8574-2007-4-151.

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2

Feng, W. Y., E. H. Lee, and J. B. Hays. "Recombinagenic processing of UV-light photoproducts in nonreplicating phage DNA by the Escherichia coli methyl-directed mismatch repair system." Genetics 129, no. 4 (1991): 1007–20. http://dx.doi.org/10.1093/genetics/129.4.1007.

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Abstract Nonreplicating lambda phage DNA in homoimmune Escherichia coli lysogens provides a useful model system for study of processes that activate DNA for homologous recombination. We measured recombination by extracting phage DNA from infected cells, using it to transfect recA recipient cells, and scoring the frequency of recombinant infective centers. With unirradiated phage, recombinant frequencies were less than 0.1%. However, recombination could be increased over 300-fold by prior UV irradiation of the phages. The dependence of recombination on UvrA function varied greatly with UV dose.
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3

Doğan, Tayfun, and Fatma Tuba Aydın. "Do Happy Children Become Happy Adults?" Journal of Humanity and Society (insan & toplum) 11, no. 1 (2021): 69–96. http://dx.doi.org/10.12658/m0437.

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Many psychological theories emphasize the significance of early childhood events. A review of the literature reveals that studies concentrate on the consequences of adverse childhood experiences on the physical and mental health of individuals. A few studies have so far examined the effects of positive childhood experiences on mental health. This research aims to investigate the relationship between positive childhood experiences and happiness. 695 adults (488 female and 207 male) participated in the study. Positive Childhood Experiences Scale served to gather the data regarding the childhood
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4

HÖFLING, José Francisco, Denise M. P. SPOLIDÓRIO, Cássio Vicente PEREIRA, Edvaldo A. R. ROSA, and Daniela MOREIRA. "Presença de Streptococcus mutans e Streptococcus mutans associado a Streptococcus sobrinus em escolares de diferentes classes sócio-econômicas e sua relação com a atividade cariogênica dessas populações." Revista de Odontologia da Universidade de São Paulo 13, no. 2 (1999): 173–80. http://dx.doi.org/10.1590/s0103-06631999000200012.

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As espécies de estreptococos do grupo mutans mais predominantemente isoladas de amostras salivares têm sido S. mutans e S. sobrinus. A detecção desses microrganismos em escolares de diferentes classes sócio-econômicas e sua relação com a atividade cariogênica dessas populações foi estudada, em correlação com os parâmetros clínicos CPOD, CPOS, ceo e ceos. Duzentos (200) escolares pertencentes a cinco categorias sócio-econômicas foram separados em subgrupos de acordo com as espécies de microrganismos identificadas em suas amostras salivares. Do total de crianças analisadas, 103 (51,0%) apresenta
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Singh, Paramdeep, Avninder Kaur, Neerja Kakkar, Manjeet Kaur, and Shivesh Acharya. "Quantitative Correlation of Salivary Streptococcus Mutans Count Amongst Siblings and their Mothers." Dental Journal of Advance Studies 05, no. 02 (2017): 090–96. http://dx.doi.org/10.1055/s-0038-1672089.

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Abstract Aim: The present study was planned to analyze quantitative correlation of salivary Streptococcus Mutans (S. Mutans) in siblings and their mothers. Materials and Methods: Quantitative analysis of S. Mutans in saliva was performed using Dentocult SM strip mutans kit (Orion Diagnostica, Helsinki, Finland) in closely related members of the family i.e. siblings along with their mothers. Results: S. Mutans count between the siblings showed positive correlation which was statistically highly significant. The younger childrens’ S. Mutans count was very highly correlated (rs = 0.711) with the
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6

Zeng, Y., M. Youssef, L. Wang, et al. "Identification of Non-Streptococcus mutans Bacteria from Predente Infant Saliva Grown on Mitis-Salivarius-Bacitracin Agar." Journal of Clinical Pediatric Dentistry 44, no. 1 (2020): 28–34. http://dx.doi.org/10.17796/1053-4625-44.1.5.

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Objective: Although mitis-salivarius-bacitracin (MSB) agar is a commonly used selective medium for detecting Streptococcus mutans in clinical studies, non-S. mutans microorganisms are cultivatable on MSB agar. Since few studies have identified non-S. mutans bacteria grown on MSB, this study aimed to identify and differentiate MSB-grown non-S. mutans bacteria from predente infants' oral cavity. Study design: The saliva from 51 predente infants were plated on MSB agars. Bacteria colonies were characterized based on their morphology under direct visualization and light microscopic observation. Co
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7

Ong, Seung-Hwan, Jongsoo Kim, Dong-Heon Baek, and Seunghoon Yoo. "Comparison of Cariogenic Characteristics between Fluoride-sensitive and Fluoride-resistant Streptococcus mutans." JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY 47, no. 4 (2020): 397–405. http://dx.doi.org/10.5933/jkapd.2020.47.4.397.

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The aim of this study is to compare cariogenic characteristics of fluoride-sensitive <i>Streptococcus mutans</i> [fluoride-sensitive (FS) <i>S. mutans</i> ] and fluoride-resistant <i>Streptococcus mutans</i> [fluoride-resistant (FR) <i>S. mutans</i>] in the presence of sucrose, and to evaluate its effect on cariogenic biofilm formation. <i>S. mutans</i> ATCC 25175 was continuously cultured in trypticase soy broth (TSB) containing NaF (70 ppm) for 40 days to generate FR <i>S. mutans</i> . FS and FR <i>S. mutans</i&
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8

Alves, Alessandra C., Ruchele D. Nogueira, Rafael N. Stipp, et al. "Prospective study of potential sources of Streptococcus mutans transmission in nursery school children." Journal of Medical Microbiology 58, no. 4 (2009): 476–81. http://dx.doi.org/10.1099/jmm.0.005777-0.

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Transmission of Streptococcus mutans, a major dental caries pathogen, occurs mainly during the first 2.5 years of age. Children appear to acquire S. mutans mostly from their mothers, but few studies have investigated non-familial sources of S. mutans transmission. This study prospectively analysed initial S. mutans oral colonization in 119 children from nursery schools during a 1.5-year period and tracked the transmission from child to child, day-care caregiver to child and mother to child. Children were examined at baseline, when they were 5–13 months of age, and at 6-month intervals for dete
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9

Wang, Bing-Yan, and Howard K. Kuramitsu. "Interactions between Oral Bacteria: Inhibition of Streptococcus mutans Bacteriocin Production by Streptococcus gordonii." Applied and Environmental Microbiology 71, no. 1 (2005): 354–62. http://dx.doi.org/10.1128/aem.71.1.354-362.2005.

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ABSTRACT Streptococcus mutans has been recognized as an important etiological agent in human dental caries. Some strains of S. mutans also produce bacteriocins. In this study, we sought to demonstrate that bacteriocin production by S. mutans strains GS5 and BM71 was mediated by quorum sensing, which is dependent on a competence-stimulating peptide (CSP) signaling system encoded by the com genes. We also demonstrated that interactions with some other oral streptococci interfered with S. mutans bacteriocin production both in broth and in biofilms. The inhibition of S. mutans bacteriocin producti
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10

Minasari, Minasari, Sri Amelia, and Nevi Tinambunan. "PERBEDAAN EFEK EKSTRAK BAWANG MERAH TERHADAP PERTUMBUHAN Streptococcus mutans DARI KARIES DAN Streptococcus mutans (ATCC® 35668™)." Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) 10, no. 3 (2018): 296–300. http://dx.doi.org/10.36911/pannmed.v10i3.144.

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Bawang merah merupakan tanaman herbal yang biasa digunakan sebagai bumbu masakan yang memiliki efek antibakteri karena adanya kandungan alkaloid, saponin, dan flavonoid. Alkaloid berfungsi dalam menghambat sintesis protein dan asam nukleat, saponin berperan dalam merusak permeabilitas membran sel, dan flavonoid berfungsi dalam menghancurkan dinding sel Streptococcus mutans. Streptococcus mutans adalah bakteri dominan terjadinya karies. Penelitian ini bertujuan untuk mengetahui efek ekstrak bawang merah terhadap pertumbuhan Streptococcus mutans dari karies dan Streptococcus mutans (ATCC® 35668™
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11

Dewanti, I. Dewa Ayu Ratna, I. Dewa Ayu Susilawati, P. Purwanto, et al. "The role of Kuniran (U. moluccensis) and Gurami (O. goramy) fish thorns and scales in increasing salivary leukocyte and monocyte cells viability against Streptococcus mutans." Dental Journal (Majalah Kedokteran Gigi) 52, no. 1 (2019): 45. http://dx.doi.org/10.20473/j.djmkg.v52.i1.p45-50.

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Background: Kuniran thorns and Gurami fish scales are rich in protein and minerals such as dentin believed to increase cell viability against Streptococcus mutans (S. mutans) that causes dental caries. These, in turn, can cause systemic diseases if left untreated. Purpose: This study aims to analyze the influence of Kuniran thorns and Gurami fishes scales on the viability of monocytes and salivary leukocytes against S. mutans. Methods: Monocytes and leukocytes salivary cells were placed on a microtiter plate and treated according to the nature of each group. This study comprised the following
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12

Gregory, Richard L. "Modified Immunogenicity of a Mucosally Administered Antigen." Clinical Diagnostic Laboratory Immunology 8, no. 3 (2001): 540–44. http://dx.doi.org/10.1128/cdli.8.3.540-544.2001.

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ABSTRACT Streptococcus mutans is present in the saliva of most individuals and is modified by salivary components bound to the cells. These saliva-bound S. mutans are swallowed, exposed to high levels of acidity in the stomach, and presented to the common mucosal immune system. Much effort has been directed to identifying the specific S. mutans antigens that the mucosal immune responses are directed against. However, little is known about the host-altered antigenic determinants that the mucosal immune system recognizes. The immunogenicity of gastrically intubated untreatedS. mutans cells, cell
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13

Dewanti, I. Dewa Ayu Ratna, Pujiana Endah Lestari, Roedy Budirahardjo та ін. "THE EFFECT OF STEEPING ROBUSTA COFFEE BEANS ON MONOCYTES: EXPRESSION OF IL-1β AND TNF-α AGAINST Streptococcus mutans". Coffee Science 14, № 4 (2019): 477. http://dx.doi.org/10.25186/cs.v14i4.1619.

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Adhesion, IL–1β, TNF–α are components that affect in inflammation. So, the effect of steeping green and black Robusta coffee beans to adhesion of <em>Streptococcus mutans</em> on this components. This study used monocytes isolated from healthy human peripheral blood using Ficoll-Hypaque centrifugation method. Monocytes were divided into eight groups, i. e. (i) Control group (untreated monocytes), (ii) <em>Streptococcus mutans</em> group (monocytes + <em>S. mutans</em>), (iii) Black Coffee 2.5 % group (monocytes + black coffee beans 2.5 % + <em>S. mutan
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14

Kurniawati, Atik, Sulistiyani, and Arina Nur Rahmah. "PERAN EKSTRAK DAUN WUNGU (GRAPTOPHYLLUM PICTUM L. GRIFF) TERHADAP ADHESI STREPTOCOCCUS MUTANS PADA NEUTROFIL." Cakradonya Dental Journal 11, no. 2 (2020): 128–34. http://dx.doi.org/10.24815/cdj.v11i2.16156.

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Streptococcus mutans (S. mutans) merupakan bakteri utama penyebab karies gigi yang mampu mendemineralisasi email, menginvasi dentin yang dapat berlanjut menjadi inflamasi pulpa (pulpitis). Streptococcus mutans menginvasi inang diawali dengan melakukan adhesi (perlekatan). Proses ini merupakan langkah awal dalam proses inflamasi. Oleh karena itu, adhesi Streptococcus. mutans pada sel inang perlu dicegah agar tidak terjadi infeksi oleh bakteri. Neutrofil merupakan sel pertahanan pertama yang datang pada proses inflamasi. Salah satu upaya untuk mencegah terjadinya adhesi tersebut bisa menggunakan
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15

Schaeken, M. J. M., J. S. Van der Hoeven, and H. C. M. Franken. "Comparative Recovery of Streptococcus mutans on Five Isolation Media, Including a New Simple Selective Medium." Journal of Dental Research 65, no. 6 (1986): 906–8. http://dx.doi.org/10.1177/00220345860650060901.

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For the isolation of Streptococcus mutans, several selective media have been developed, of which Mitis-Salivarius Sucrose Bacitracin agar (MSB) is the most widely used (Gold et al., 1973). Recently, the Trypticase Yeast-Extract Cystine agar medium (TYC, de Stoppelaar et al., 1967) was modified into a selective medium for S. mutans , called Trypticase Yeast-Extract Cystine Sucrose Bacitracin (TYCSB, van Palenstein Helderman et al., 1983). The aim of this study was to compare the recovery of S. mutans from clinical samples on Mitis-Salivarius agar (MS), MSB, TYC, and TYCSB. Further, a new simple
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16

Motta, Lara Jansiski, Carolina Cardoso Guedes, Sálua Haidar Reda, Sandra Kalil Bussadori, Kristianne Santos Porta Fernandes, and Manoela Domingues Martins. "Vacinas anticárie: uma revisão do estágio atual." ConScientiae Saúde 5, no. 1 (2008): 97–107. http://dx.doi.org/10.5585/conssaude.v5i1.436.

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Atualmente é grande o interesse dispensado ao estudo das vacinas anticárie que imunizam os indivíduos contra o Streptococcus mutans (S. mutans). Este trabalho revisa a literatura em relação aos meios de imunização ativa e passiva contra a cárie dental e à busca de uma vacina efetiva na prevenção da doença, que atue seletivamente contra as cepas cariogênicas do Streptococcus mutans (S. mutans).
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17

Wang, Junxian, Yan Shi, Shisong Jing, Haisi Dong, Dacheng Wang, and Tiedong Wang. "Astilbin Inhibits the Activity of Sortase A from Streptococcus mutans." Molecules 24, no. 3 (2019): 465. http://dx.doi.org/10.3390/molecules24030465.

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Streptococcus mutans (S. mutans) is the primary etiological agent of dental caries. The S. mutans enzyme sortase A (SrtA) is responsible for anchoring bacterial cell wall surface proteins involved in host cell attachment and biofilm formation. Thus, SrtA is an attractive target for inhibiting dental caries caused by S. mutans-associated acid fermentation. In this study, we observed that astilbin, a flavanone compound extracted from Rhizoma Smilacis Glabrae, has potent inhibitory activity against the S. mutans SrtA, with an IC50 of 7.5 μg/mL. In addition, astilbin was proven to reduce the forma
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18

Subramaniam, Priya, and Revathy Suresh. "Streptococcus Mutans Strains in Mother-Child Pairs of Children with Early Childhood Caries." Journal of Clinical Pediatric Dentistry 43, no. 4 (2019): 252–56. http://dx.doi.org/10.17796/1053-4625-43.4.5.

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Objective: Dental caries is both an infectious and transmissible disease. Maternal transfer of Mutans Streptococci occurs at an early age and is important in the initiation of dental caries in children. The aim of this study was to identify certain strains of Streptococcus mutans in mother-child pairs, of children with early childhood caries. Study design: Sixty mother-child pairs of healthy children aged 18–36 months were selected. Mothers with high levels of Streptococcus mutans in their saliva and only children with ECC were included. Dental plaque samples were collected from mother-child p
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Kholisa, Kholisa, Purwanto Purwanto, and Sri Hernawati. "Potensi Ekstrak Buah Delima Merah (Punica granatum Linn) terhadap Penurunan Jumlah Koloni Streptococcus mutans." Pustaka Kesehatan 6, no. 2 (2018): 351. http://dx.doi.org/10.19184/pk.v6i2.8655.

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Streptococcus mutans is a bacteria that initiates the formation of plaque on the tooth surface. S. mutans works by fermenting carbohydrates to produce an acidic atmosphere, so the plaque pH becomes low, this condition can lead to demineralization of enamel and dentin commonly called caries. One of alternative treatment to reduce the population of S. mutans by using herbal plants, namely red pomegranate. Red pomegranate contains flavonoids, tannins, and alkaloids as antibacterial. This study aimed to determine the inhibition of red pomegranate extract on growth of S. mutans. The method used is
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20

Mitrakul, Kemthong, Kutkao Vongsawan, Assavinee Sriutai, and Wipaphan Thosathan. "Association between S. mutans and S. sanguinis in Severe Early childhood Caries and Caries-Free Children A Quantitative Real-Time PCR Analysis." Journal of Clinical Pediatric Dentistry 40, no. 4 (2016): 281–89. http://dx.doi.org/10.17796/1053-4628-40.4.281.

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Objectives: To identify S. mutans and S. sanguinis in initial and overnight plaque between 2 groups and to analyze the association between them and caries-related factors. Study design: Collected supra gingival plaque from 140 Thai children aged 2–6 years old (S-ECC = 68, caries-free=72). Recorded plaque and gingival indices, dmft score, salivary mutans streptococci level, pH and buffer capacity. Firstly, the overnight plaque was collected, then, 4 hrs. after a thorough prophylaxis, the initial plaque was collected. Accessed parent's attitude and behavior in children's oral hygiene care and di
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21

Smith, Daniel J., William F. King, and Ronald Godiska. "Passive Transfer of Immunoglobulin Y Antibody toStreptococcus mutans Glucan Binding Protein B Can Confer Protection against Experimental Dental Caries." Infection and Immunity 69, no. 5 (2001): 3135–42. http://dx.doi.org/10.1128/iai.69.5.3135-3142.2001.

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ABSTRACT Active immunization with Streptococcus mutans glucan binding protein B (GBP-B) has been shown to induce protection against experimental dental caries. This protection presumably results from continuous secretion of salivary antibody to GBP-B, which inhibits accumulation of S. mutans within the oral biofilm. The purpose of this study was to explore the influence of short-term (9- or 24-day) passive oral administration of antibody to S. mutans GBP-B on the longer-term accumulation and cariogenicity ofS. mutans in a rat model of dental caries. Preimmune chicken egg yolk immunoglobulin Y
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Sesso, Maria Lucia Talarico, Sanivia Aparecida de Lima Pereira, Vinicius Rangel Geraldo-Martins, Virginia Paes Leme Ferriani, and Ruchele Dias Nogueira. "Detection of Immunoglobulin G Against Oral Streptococci in Peripheral and Umbilical Cord Blood." Journal of Health Sciences 22, no. 4 (2020): 270–75. http://dx.doi.org/10.17921/2447-8938.2020v22n4p270-275.

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AbstractThe maternal Immunoglobulin G (IgG) antibodies transferred during the intrauterine life represents the main newborn immune protection against several intestinal and respiratory infection. However, there is little information about the reactivity and function of IgG from cord blood against newborn oral colonization. The aims this study was to evaluate the presence of IgG against Streptococcus mitis, Streptococcus mutans and theirs mains virulence antigens (GbpB, Ag I/II and Gtf) in peripheral blood (PB) samples from mothers with S. mutans or not in the saliva (SA) and compare with umbil
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23

Xiong, Kaixin, Xuan Chen, Hantao Hu, Huihui Hou, Peng Gao, and Ling Zou. "Antimicrobial Effect of a Peptide Containing Novel Oral Spray on Streptococcus mutans." BioMed Research International 2020 (March 11, 2020): 1–13. http://dx.doi.org/10.1155/2020/6853652.

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Objective. To investigate the antibacterial effect of a novel antimicrobial peptide containing oral spray GERM CLEAN on Streptococcus mutans (S. mutans) in vitro and further explore the related mechanisms at phenotypic and transcriptional levels. Methods. The disk diffusion method was used to preliminarily appraise the antimicrobial effect of GERM CLEAN. The minimal inhibitory concentration (MIC) of GREM CLEAN towards S. mutans was determined by the broth dilution method. S. mutans virulence-related phenotypic assays including initial adhesive assay, pH drop, exopolysaccharides (EPS), and biof
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Mallaley, P. P., S. A. Halperin, A. Morris, A. MacMillan, and S. F. Lee. "Expression of a pertussis toxin S1 fragment by inducible promoters in oral Streptococcus and the induction of immune responses during oral colonization in mice." Canadian Journal of Microbiology 52, no. 5 (2006): 436–44. http://dx.doi.org/10.1139/w05-151.

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Previous work aimed at developing a live oral vaccine expressing pertussis toxin S1 fragment on the surface of the bacterium Streptococcus gordonii elicited a lower than expected antibody response, perhaps because of low antigen expression. In this study, in-frame promoter fusions were constructed to investigate whether an increase in antigen production by the streptococcal vaccine strain results in a better antibody response. The promoters tested were (i) the Streptococcus mutans sucrose-inducible fructosyltransferase (ftf) promoter and (ii) the Bacillus subtilis/Escherichia coli chimeric tet
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Liu, Jinman, Chenggang Wu, I.-Hsiu Huang, Justin Merritt, and Fengxia Qi. "Differential response of Streptococcus mutans towards friend and foe in mixed-species cultures." Microbiology 157, no. 9 (2011): 2433–44. http://dx.doi.org/10.1099/mic.0.048314-0.

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In the oral biofilm, the ‘mitis’ streptococci are among the first group of organisms to colonize the tooth surface. Their proliferation is thought to be an important factor required for antagonizing the growth of cariogenic species such as Streptococcus mutans. In this study, we used a three-species mixed culture to demonstrate that another ubiquitous early colonizing species, Veillonella parvula, can greatly affect the outcome of the competition between a pair of antagonists such as S. mutans and Streptococcus gordonii. Transcriptome analysis further revealed that S. mutans responds different
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Jarosz, Lucja M., Dong Mei Deng, Henny C. van der Mei, Wim Crielaard, and Bastiaan P. Krom. "Streptococcus mutans Competence-Stimulating Peptide Inhibits Candida albicans Hypha Formation." Eukaryotic Cell 8, no. 11 (2009): 1658–64. http://dx.doi.org/10.1128/ec.00070-09.

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ABSTRACT The oral cavity is colonized by microorganisms growing in biofilms in which interspecies interactions take place. Streptococcus mutans grows in biofilms on enamel surfaces and is considered one of the main etiological agents of human dental caries. Candida albicans is also commonly found in the human oral cavity, where it interacts with S. mutans. C. albicans is a polymorphic fungus, and the yeast-to-hypha transition is involved in virulence and biofilm formation. The aim of this study was to investigate interkingdom communication between C. albicans and S. mutans based on the product
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Biswas, Indranil, Laura Drake, Dasha Erkina, and Saswati Biswas. "Involvement of Sensor Kinases in the Stress Tolerance Response of Streptococcus mutans." Journal of Bacteriology 190, no. 1 (2007): 68–77. http://dx.doi.org/10.1128/jb.00990-07.

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ABSTRACT The gram-positive bacterium Streptococcus mutans is the primary causative agent in the formation of dental caries in humans. The ability of S. mutans to adapt and to thrive in the hostile environment of the oral cavity suggests that this cariogenic pathogen is capable of sensing and responding to different environmental stimuli. This prompted us to investigate the role of two-component signal transduction systems (TCS), particularly the sensor kinases, in response to environmental stresses. Analysis of the annotated genome sequence of S. mutans indicates the presence of 13 putative TC
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Chen, Hong, Yingming Yang, Michael D. Weir, et al. "Regulating Oral Biofilm from Cariogenic State to Non-Cariogenic State via Novel Combination of Bioactive Therapeutic Composite and Gene-Knockout." Microorganisms 8, no. 9 (2020): 1410. http://dx.doi.org/10.3390/microorganisms8091410.

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The objectives were to investigate a novel combination of gene-knockout with antimicrobial dimethylaminohexadecyl methacrylate (DMAHDM) composite in regulating oral biofilm from a cariogenic state toward a non-cariogenic state. A tri-species biofilm model included cariogenic Streptococcus mutans (S. mutans), and non-cariogenic Streptococcus sanguinis (S. sanguinis) and Streptococcus gordonii (S. gordonii). Biofilm colony-forming-units (CFUs), lactic acid and polysaccharide production were measured. TaqMan real-time-polymerase-chain reaction was used to determine the percentage of each species
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Petersen, F. C., S. Assev, H. C. van der Mei, H. J. Busscher, and A. A. Scheie. "Functional Variation of the Antigen I/II Surface Protein in Streptococcus mutans and Streptococcus intermedius." Infection and Immunity 70, no. 1 (2002): 249–56. http://dx.doi.org/10.1128/iai.70.1.249-256.2002.

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ABSTRACT Although Streptococcus intermedius and Streptococcus mutans are regarded as members of the commensal microflora of the body, S. intermedius is often associated with deep-seated purulent infections, whereas S. mutans is frequently associated with dental caries. In this study, we investigated the roles of the S. mutans and S. intermedius antigen I/II proteins in adhesion and modulation of cell surface characteristics. By using isogenic mutants, we show that the antigen I/II in S. mutans, but not in S. intermedius, was involved in adhesion to a salivary film under flowing conditions, as
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30

Emilson, C. G., B. Lindquist, and K. Wennerholm. "Recolonization of Human Tooth Surfaces by Streptococcus mutans after Suppression by Chlorhexidine Treatment." Journal of Dental Research 66, no. 9 (1987): 1503–8. http://dx.doi.org/10.1177/00220345870660091801.

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In eight subjects who were initially highly colonized with Streptococcus mutans and who used a 1% chlorhexidine gel, the numbers of this organism were suppressed in both plaque and saliva. Bacterial plaque samples were obtained from all tooth surfaces, and the recolonization pattern of S. mutans was studied over a 26-week period. At baseline, 83% of all surfaces harbored S. mutans with buccal surfaces colonized in higher frequency than the others. After chlorhexidine treatment, the proportion of tooth surfaces colonized by S. mutans was reduced to a low level. Re-appearance was slow. S. mutans
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Lumaksita, Paulus Paksi Inggil, David Sugihartana, and Sri Larnani. "Efek Penghambatan Ekstrak Akuades Daun Ocimum basilicum terhadap Streptococcus mutans In Vitro." Jurnal Kedokteran Brawijaya 30, no. 2 (2018): 87. http://dx.doi.org/10.21776/ub.jkb.2018.030.02.2.

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<p>Daun kemangi (Ocimum basilicum) telah diteliti ekstraknya sebagai antibakteri patogen pangan. Penelitian eksperimental antibakteri dari ekstrak daun Ocimum basilicum terhadap patogen di rongga mulut, termasuk Streptococcus mutans, masih harus diperdalam. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun Ocimum basilicum terhadap penghambatan pertumbuhan Streptococcus mutans. Daun Ocimum basilicum diekstraksi dengan metode maserasi menggunakan akuades steril. Ekstrak diuji penghambatannya terhadap pertumbuhan Streptococcus mutans dalam larutan NaCl fisiologis dengan metode di
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Endriani, Rita, Fajri Marindra Siregar, Elita Rafni, Rahmat Kemal Azhari, and Jefrizal Jefrizal. "Identifikasi gen kariogenik glukosiltransferase Streptococcus mutans pada pasien karies gigiIdentification of Streptococcus mutans cariogenic gene glucosyltransferase (gtf) in dental caries patients." Jurnal Kedokteran Gigi Universitas Padjadjaran 33, no. 1 (2021): 14. http://dx.doi.org/10.24198/jkg.v33i1.30397.

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Pendahuluan: Streptococcus mutans (S. mutans) merupakan bakteri yang mempunyai glukosiltransferase surface (GTFs) yang berperan pada proses perlekatan dan virulensi bakteri pada permukaan gigi. Enzim GTFs terdiri atas tiga jenis enzim GTFs yaitu GTFB, GTFC dan GTFD dan masing-masing enzim ini dikode oleh gen gtfB, gtfC dan gtfD yang juga berperan sebagai prekursor dalam adhesi seluler plak gigi yang dapat menyebabkan karies gigi. Tujuan penelitian adalah mengidentifikasi gen gtfC dan gtfD S. mutans pada pasien karies gigi. Metode: Penelitian dilakukan dengan consecutive sampling. Sampel peneli
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Hosoki, Satoshi, Satoshi Saito, Shuichi Tonomura, et al. "Oral Carriage of Streptococcus mutans Harboring the cnm Gene Relates to an Increased Incidence of Cerebral Microbleeds." Stroke 51, no. 12 (2020): 3632–39. http://dx.doi.org/10.1161/strokeaha.120.029607.

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Background and Purpose: Cerebral microbleeds (CMB) are associated with stroke and cognitive impairment. We previously reported a high prevalence of CMB in people with Streptococcus mutans expressing Cnm, a collagen-binding protein in the oral cavity. S. mutans is a major pathogen responsible for dental caries. Repeated challenge with S. mutans harboring the cnm gene encoding Cnm induced cerebral bleeding in stroke-prone spontaneously hypertensive rats. The purpose of this longitudinal study is to examine the relationship of cnm -positive S. mutans to the development of CMB. Methods: We retrosp
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Doméjean, S., L. Zhan, P. K. DenBesten, J. Stamper, W. T. Boyce, and J. D. Featherstone. "Horizontal Transmission of Mutans Streptococci in Children." Journal of Dental Research 89, no. 1 (2009): 51–55. http://dx.doi.org/10.1177/0022034509353400.

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It has not been established whether transmission of mutans streptococci occurs between unrelated children older than 4 years of age. The aim of the study was to investigate the possible transmission of mutans streptococci genotypes from child to child in kindergarten. We studied 96 children (ages 5–6 yrs) in three San Francisco Bay Area public schools. Mutans streptococci colonies from each child were isolated from selective culture on Mitis Salivarius Sucrose Bacitracin agar. We used arbitrary primed polymerase chain reactions to determine the mutans streptococci genotypes. Two children (not
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Wan, S. X., J. Tian, Y. Liu, A. Dhall, H. Koo, and G. Hwang. "Cross-Kingdom Cell-to-Cell Interactions in Cariogenic Biofilm Initiation." Journal of Dental Research 100, no. 1 (2020): 74–81. http://dx.doi.org/10.1177/0022034520950286.

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Candida albicans is known to form polymicrobial biofilms with various Streptococcus spp., including mitis and mutans group streptococci. Streptococcus gordonii (mitis group) has been shown to bind avidly to C. albicans hyphae via direct cell-to-cell interaction, while the cariogenic pathogen Streptococcus mutans (mutans group) interacts with the fungal cells via extracellular glucans. However, the biophysical properties of these cross-kingdom interactions at the single-cell level during the early stage of biofilm formation remain understudied. Here, we examined the binding forces between S. mu
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Salli, K., E. Söderling, J. Hirvonen, U. K. Gürsoy, and A. C. Ouwehand. "Influence of 2′-fucosyllactose and galacto-oligosaccharides on the growth and adhesion of Streptococcus mutans." British Journal of Nutrition 124, no. 8 (2020): 824–31. http://dx.doi.org/10.1017/s0007114520001956.

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AbstractHuman milk oligosaccharides, such as 2′-fucosyllactose (2′-FL), and galacto-oligosaccharides (GOS), a prebiotic carbohydrate mixture, are being increasingly added to infant formulas, necessitating the understanding of their impact on the oral microbiota. Here, for the first time, the effects of 2′-FL and GOS on the planktonic growth and adhesion characteristics of the caries-associated oral pathogen Streptococcus mutans were assessed, and the results were compared against the effects of xylitol, lactose and glucose. There were differences in S. mutans growth between 2′-FL and GOS. None
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Indrawati, Retno. "Horizontal transmission of Streptococcus mutans in children attending kindergarten." Dental Journal (Majalah Kedokteran Gigi) 51, no. 4 (2018): 216. http://dx.doi.org/10.20473/j.djmkg.v51.i4.p216-221.

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Background: Transmission of Streptococcus mutans (S. mutans), the main pathogen found in dental caries, is particularly prevalent during the first two years of infancy. Numerous children are reportedly infected with S. mutans by their mothers with early initial acquisition of the condition considered to carry a higher risk of subsequent dental caries. Purpose: This research aimed to examine the possibility of horizontal transmission of S. mutans in children attending Surabaya-based kindergartens. Methods: The number of subjects who satisfied the inclusion criteria totaled 146. Dental plaque wa
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Murniwati, Defriman Djafri, Berlian Kurniawati, Susi, and Minarni. "EFEKTIVITAS INFUSUM DAUN BELIMBING WULUH (Averrhoa bilimbi) TERHADAP PERTUMBUHAN Streptococcus mutans." Cakradonya Dental Journal 11, no. 1 (2019): 8–12. http://dx.doi.org/10.24815/cdj.v11i1.13622.

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Daun belimbing wuluh (Averrhoa bilimbi) bersifat antibakteri karena mengandung zat flavonoid, tanin,saponin dan alkaloid yang berpotensi digunakan sebagai biomaterial penghambat pertumbuhanStreptococcus mutans. Tujuan penelitian ini adalah untuk menetapkan efektifitas daun belimbing wuluhterhadap pertumbuhan Streptococcus mutans, dengan cara membandingkan berbagai konsentrasi infusumdaun ini (25%, 50%, 75% dan 100%). Penelitian eksperimental ini dilakukan secara in vitro meggunakan6 cakram mengandung infusum yang direndam dan ditanamkan pada media agar darah yang ditumbuhiS. mutans. S. mutans
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Pradiptama, Yura, Marijam Purwanta, and Harianto Notopuro. "Antibacterial Effects of Fluoride in Streptococcus mutans Growth in Vitro." Biomolecular and Health Science Journal 2, no. 1 (2019): 1. http://dx.doi.org/10.20473/bhsj.v2i1.13232.

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Introduction: Streptococcus mutans is a gram-positive coccus commonly found in the human oral cavity and is a pathogen of dental caries. S. mutans known to form biofilm in infective endocarditis heart-valve. Fluoride usage known to reduce the risk of dental caries. This study aims to analyze how usage of fluoride in inhibiting S. mutans growth.Methods: This study was an experimental study. Antibacterial activity test was performed to evaluate the minimum inhibitory concentration (MIC) using dilution method of sodium fluoride. The minimum bactericidal concentration (MBC) was determined by cultu
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Sari, Emel, and Ilhan Birinci. "Microbiological Evaluation of 0.2% Chlorhexidine Gluconate Mouth Rinse in Orthodontic Patients." Angle Orthodontist 77, no. 5 (2007): 881–84. http://dx.doi.org/10.2319/080506-320.1.

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Abstract Objective: To assess the effectiveness of 0.2% chlorhexidine gluconate mouth rinse on Streptococcus mutans and lactobacilli in orthodontic patients with fixed appliances. Materials and Methods: Twenty patients, aged 13–18, with fixed orthodontic appliances participated in the study. The levels of S mutans and lactobacilli in saliva samples were evaluated at four stages: at the beginning of the orthodontic treatment, at least 2 weeks after the bonding of brackets, 1 week after the introduction of 0.2% chlorhexidine gluconate mouth rinse, and at the fourth week. The changes in S mutans
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Rupf, S., M. Hannig, K. Breitung, et al. "Phenotypic Heterogeneity of Streptococcus mutans in Dentin." Journal of Dental Research 87, no. 12 (2008): 1172–76. http://dx.doi.org/10.1177/154405910808701203.

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Information concerning phenotypic heterogeneity of Streptococcus mutans in carious dentin is sparse. Matrix-assisted laser-desorption/ionization-time-of-flight mass-spectrometry (MALDI-TOF-MS) facilitates the phenotypic differentiation of bacteria to the subspecies level. To verify a supposed influence of restorative treatment on the phenotypic heterogeneity of S. mutans, we isolated and compared a total of 222 S. mutans strains from dentin samples of 21 human deciduous molars during caries excavation (T1) and 8 wks (T2) after removal of the temporary restoration. Phenotypic heterogeneity was
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Fransiska, F., Archadian Nuryanti, and Rini Maya Puspita. "Pengaruh Lama Paparan Gelombang Ultrasonik Frekuensi Terapi terhadap Jumlah Koloni Bakteri Streptococcus mutans." Majalah Kedokteran Gigi Indonesia 19, no. 1 (2016): 1. http://dx.doi.org/10.22146/majkedgiind.15590.

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Latar Belakang. Gelombang Untrasonik telah digunakan untuk terapi dan diagnosis, di klinik kedokteran gigi popular digunakan untuk ultrasonik skaler. Efek termal dan nontermal gelombang ultrasonik dapat mempengaruhi lingkungan tumbuh bakteri, merusak enzim bakteri, dan struktur bakteri. Streptococcus mutans merupakan bakteri penyebab karies gigi. Tujuan penelitian. Penelitian ini bertujuan untuk mengetahui pengaruh lama paparan gelombang ultrasonik frekuensi terapi 3,5 MHz terhadap jumlah koloni bakteri Streptococcus mutans. Cara penelitian. Penelitian ini dilakukan pada 20 buah cawan petri ya
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Rahman, Friska Ani, Tetiana Haniastuti, and Trianna Wahyu Utami. "The effect of ethanol extract of soursop leaf (Annona muricata L.) on Adhesion of Streptococcus mutans ATCC 35668 to hydroxyapatite discs." Majalah Kedokteran Gigi Indonesia 4, no. 1 (2018): 22. http://dx.doi.org/10.22146/majkedgiind.24852.

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The demineralization of dental hard tissues can be caused by dental plaque. Dental plaque contains various components, especially bacteria attached to the extracellular matrix. Streptococcus mutans (S. mutans) has extracellular glucan as adhesin that is important in the attachment mechanism of tooth surface. The natural substance can be used for preventing plaque formation by inhibiting the attachment of S. mutans. Soursop plant has been used in treating various diseases. The leaves of the soursop (Annona muricata L.) are used as a material to inhibit potential attachment of bacteria S. mutans
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Nogueira, Ruchele D., Alessandra C. Alves, Marcelo H. Napimoga, Daniel J. Smith, and Renata O. Mattos-Graner. "Characterization of Salivary Immunoglobulin A Responses in Children Heavily Exposed to the Oral Bacterium Streptococcus mutans: Influence of Specific Antigen Recognition in Infection." Infection and Immunity 73, no. 9 (2005): 5675–84. http://dx.doi.org/10.1128/iai.73.9.5675-5684.2005.

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ABSTRACT The initial infection of children by Streptococcus mutans, the main pathogen of dental caries, depends on the ability of S. mutans to adhere and accumulate on tooth surfaces. These processes involve the adhesin antigen I/II (AgI/II), glucosyltransferases (GTF) and glucan-binding protein B (GbpB), each a target for anticaries vaccines. The salivary immunoglobulin A (IgA) antibody responses to S. mutans antigens (Ags) were characterized in 21 pairs of 5- to 13-month-old children. Pairs were constructed with one early S. mutans-infected and one noninfected child matched by age, racial ba
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Nomura, Ryota, Kazuhiko Nakano, Naho Taniguchi, et al. "Molecular and clinical analyses of the gene encoding the collagen-binding adhesin of Streptococcus mutans." Journal of Medical Microbiology 58, no. 4 (2009): 469–75. http://dx.doi.org/10.1099/jmm.0.007559-0.

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Streptococcus mutans is a known pathogen of dental caries and its major cell surface antigens have been widely investigated. Recently, an approximately 120 kDa Cnm protein with binding properties to type I collagen was identified, and its encoding gene (cnm) cloned and sequenced. In the present study, we sequenced cnm from 47 different clinical S. mutans strains and found that the nucleotide alignment of the collagen-binding domain was well conserved. We devised a PCR method for identifying the cnm gene, examined the prevalence of cnm-positive S. mutans strains in various mother–child groups,
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Alves, Mariana de Sá, Luciana Ruano de Oliveira Fugisaki, Jéssica Diane dos Santos, et al. "Antifungal effects of Streptococcus mutans extract on Candida strains susceptible and resistant to fluconazole: An in vivo study." Medical Mycology 59, no. 7 (2021): 744–47. http://dx.doi.org/10.1093/mmy/myab008.

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Abstract Previous studies showed that the crude extract obtained from Streptococcus mutans inhibited the growth of Candida albicans reference strains. In this study, we evaluated whether the antifungal effects of S. mutans extract can be extended to clinical Candida isolates, including C. albicans and non-abicans strains with different susceptibilities to fluconazole. We verified that S. mutans extract increased the survival of Galleria mellonella larvae infected with C. albicans and C. glabrata and inhibited the fungal cells in hemolymph. These antifungal effects occurred for both fluconazole
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Saha, S., C. Tomaro-Duchesneau, L. Rodes, M. Malhotra, M. Tabrizian, and S. Prakash. "Investigation of probiotic bacteria as dental caries and periodontal disease biotherapeutics." Beneficial Microbes 5, no. 4 (2014): 447–60. http://dx.doi.org/10.3920/bm2014.0011.

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Oral diseases, specifically dental caries and periodontal disease, are characterised by increases in pathogenic microorganisms, increased demineralisation and increased inflammation and levels of inflammatory markers. Despite the therapeutic strategies, oral diseases have elevated prevalence rates. Recent work has demonstrated that probiotic bio-therapeutics can decrease oral pathogen counts, including caries-causing Streptococcus mutans and oral inflammation. The aim of this work was to investigate putative probiotic bacteria, selected for S. mutans inhibition and for their oral health-promot
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Kunarti, Sri, S. Sukaton, and Ajeng Hayyuning Citrasari. "Effect of Different Radiation Times on the Antibacterial Ability of Laser Diodes (650 nm) on Streptococcus mutans." Conservative Dentistry Journal 9, no. 1 (2019): 22. http://dx.doi.org/10.20473/cdj.v9i1.2019.22-27.

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Background: Streptococccus mutans is an acid-producing gram-positive bacterium that colonizes the tooth surface and causes damage to the hard tissue of the tooth. S. mutans is known as the main agent that causes caries. Photodynamic therapy (PDT) consisting of photosensitizers and a light source, such as a laser beam, is considered to have an antibacterial effect on S. mutans. However, the factors that influence the antibacterial effects of the lasers, such as the amount of energy, wavelength, use of photosensitizer, and the duration of radiation still need to be studied. Aim: To determine the
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Choi, Jung-Yoon, Chooryung Judi Chung, Keun-Taek Oh, Yoon-Jeong Choi, and Kyung-Ho Kim. "Photocatalytic Antibacterial Effect of TiO2 Film of TiAg on Streptococcus mutans." Angle Orthodontist 79, no. 3 (2009): 528–32. http://dx.doi.org/10.2319/012108-169.1.

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Abstract Objective: To test through various oxidation procedures the differences in antibacterial activities against Streptococcus mutans (S mutans) of Titanium (Ti) and Titanium silver (TiAg) metals coated with TiO2. Materials and Methods: This study examined the photocatalytic antibacterial effects on S mutans of Ti and TiAg ubstrates coated with two crystalline forms of TiO2 by thermal and anodic oxidation. A bacterial suspension of S mutans was pipetted onto TiO2-coated metal specimens and uncoated specimens with ultraviolet A (UVA) illumination for 20 to 100 minutes. The same specimen wit
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Scoffield, J., S. Michalek, G. Harber, P. Eipers, C. Morrow, and H. Wu. "Dietary Nitrite Drives Disease Outcomes in Oral Polymicrobial Infections." Journal of Dental Research 98, no. 9 (2019): 1020–26. http://dx.doi.org/10.1177/0022034519855348.

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Streptococcus mutans resides in the oral polymicrobial biofilm and is a major contributor to the development of dental caries. Interestingly, high salivary nitrite concentrations have been associated with a decreased prevalence of dental caries. Moreover, the combination of hydrogen peroxide–producing oral commensal streptococci and nitrite has been shown to mediate the generation of reactive nitrogen species, which have antimicrobial activity. The goal of this study was to examine whether nitrite affects S. mutans virulence during polymicrobial infections with the commensal Streptococcus para
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