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Relevant bibliographies by topics / Mycobacterium DNA Binding Protein

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Academic literature on the topic 'Mycobacterium DNA Binding Protein'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 September 2023

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Journal articles on the topic "Mycobacterium DNA Binding Protein"

1

Peña, Carol E. A., J. Michelle Kahlenberg, and Graham F. Hatfull. "Protein-DNA Complexes in Mycobacteriophage L5 Integrative Recombination." Journal of Bacteriology 181, no. 2 (1999): 454–61. http://dx.doi.org/10.1128/jb.181.2.454-461.1999.

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ABSTRACT The temperate mycobacteriophage L5 integrates site specifically into the genomes of Mycobacterium smegmatis,Mycobacterium tuberculosis, and Mycobacterium bovis bacillus Calmette-Guérin. This integrative recombination event occurs between the phage L5 attP site and the mycobacterial attB site and requires the phage-encoded integrase and mycobacterial-encoded integration host factor mIHF. Here we show that attP, Int-L5, and mIHF assemble into a recombinationally active complex, the intasome, which is capable of attB capture and formation of products. The arm-type integrase binding site

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Singhal, Anshika, Richa Virmani, Saba Naz, et al. "Methylation of two-component response regulator MtrA in mycobacteria negatively modulates its DNA binding and transcriptional activation." Biochemical Journal 477, no. 23 (2020): 4473–89. http://dx.doi.org/10.1042/bcj20200455.

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Post-translational modifications such as phosphorylation, nitrosylation, and pupylation modulate multiple cellular processes in Mycobacterium tuberculosis. While protein methylation at lysine and arginine residues is widespread in eukaryotes, to date only two methylated proteins in Mtb have been identified. Here, we report the identification of methylation at lysine and/or arginine residues in nine mycobacterial proteins. Among the proteins identified, we chose MtrA, an essential response regulator of a two-component signaling system, which gets methylated on multiple lysine and arginine resid

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Bai, Guangchun, Michaela A. Gazdik, Damen D. Schaak, and Kathleen A. McDonough. "The Mycobacterium bovis BCG Cyclic AMP Receptor-Like Protein Is a Functional DNA Binding Protein In Vitro and In Vivo, but Its Activity Differs from That of Its M. tuberculosis Ortholog, Rv3676." Infection and Immunity 75, no. 11 (2007): 5509–17. http://dx.doi.org/10.1128/iai.00658-07.

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ABSTRACT Mycobacterium tuberculosis Rv3676 encodes a cyclic AMP (cAMP) receptor-like protein (CRPMt) that has been implicated in global gene regulation and may play an important role during tuberculosis infection. The CRPMt ortholog in Mycobacterium bovis BCG, CRPBCG, is dysfunctional in an Escherichia coli CRP competition assay and has been proposed as a potential source of M. bovis BCG's attenuation. We compared CRPBCG and CRPMt in vitro and in vivo, in M. bovis BCG and M. tuberculosis, to evaluate CRPBCG's potential function in a mycobacterial system. Both proteins formed dimers in mycobact

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Gigante, Adriano M., Francisco Olivença, Maria João Catalão, et al. "The Mycobacteriophage Ms6 LysB N-Terminus Displays Peptidoglycan Binding Affinity." Viruses 13, no. 7 (2021): 1377. http://dx.doi.org/10.3390/v13071377.

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Double-stranded DNA bacteriophages end their lytic cycle by disrupting the host cell envelope, which allows the release of the virion progeny. Each phage must synthesize lysis proteins that target each cell barrier to phage release. In addition to holins, which permeabilize the cytoplasmic membrane, and endolysins, which disrupt the peptidoglycan (PG), mycobacteriophages synthesize a specific lysis protein, LysB, capable of detaching the outer membrane from the complex cell wall of mycobacteria. The family of LysB proteins is highly diverse, with many members presenting an extended N-terminus.

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Spreadbury, Claire L., Mark J. Pallen, Tim Overton, et al. "Point mutations in the DNA- and cNMP-binding domains of the homologue of the cAMP receptor protein (CRP) in Mycobacterium bovis BCG: implications for the inactivation of a global regulator and strain attenuation." Microbiology 151, no. 2 (2005): 547–56. http://dx.doi.org/10.1099/mic.0.27444-0.

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The genome of Mycobacterium tuberculosis H37Rv includes a homologue of the CRP/FNR (cAMP receptor protein/fumarate and nitrate reduction regulator) family of transcription regulators encoded by Rv3676. Sequencing of the orthologous gene from attenuated Mycobacterium bovis Bacille Calmette–Guérin (BCG) strains revealed point mutations that affect the putative DNA-binding and cNMP-binding domains of the encoded protein. These mutations are not present in the published sequences of the Rv3676 orthologues in M. bovis, M. tuberculosis or Mycobacterium leprae. An Escherichia coli lacZ reporter syst

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ZAWILAK, Anna, Agnieszka KOIS, Grażyna KONOPA, Aleksandra SMULCZYK-KRAWCZYSZYN, and Jolanta ZAKRZEWSKA-CZERWIŃSKA. "Mycobacterium tuberculosis DnaA initiator protein: purification and DNA-binding requirements." Biochemical Journal 382, no. 1 (2004): 247–52. http://dx.doi.org/10.1042/bj20040338.

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The Mycobacterium tuberculosis oriC (the origin of chromosomal replication) region contains 13 non-perfect DnaA boxes. The M. tuberculosis initiator protein, DnaA, was overexpressed in Escherichia coli as a soluble His-tagged fusion protein. The purified protein His6MtDnaA was investigated for its binding properties to DnaA boxes from the oriC region. Gel retardation demonstrated that the DnaA from M. tuberculosis requires two DnaA boxes for efficient binding. Electron microscopy as well as DNase I footprinting showed that the His6MtDnaA protein binds to four specific regions, which correspond

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Sala, Claudia, Francesca Forti, Elisabetta Di Florio, et al. "Mycobacterium tuberculosis FurA Autoregulates Its Own Expression." Journal of Bacteriology 185, no. 18 (2003): 5357–62. http://dx.doi.org/10.1128/jb.185.18.5357-5362.2003.

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ABSTRACT The furA-katG region of Mycobacterium tuberculosis, encoding a Fur-like protein and the catalase-peroxidase, is highly conserved among mycobacteria. Both genes are induced upon oxidative stress. In this work we analyzed the M. tuberculosis furA promoter region. DNA fragments were cloned upstream of the luciferase reporter gene, and promoter activity in Mycobacterium smegmatis was measured in both the presence and absence of oxidative stress. The shortest fragment containing an inducible promoter extends 45 bp upstream of furA. In this region, −35 and −10 promoter consensus sequences c

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Bai, Guangchun, Lee Ann McCue, and Kathleen A. McDonough. "Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a Cyclic AMP Receptor Protein-Like DNA Binding Protein." Journal of Bacteriology 187, no. 22 (2005): 7795–804. http://dx.doi.org/10.1128/jb.187.22.7795-7804.2005.

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ABSTRACT Little is known about cyclic AMP (cAMP) function in Mycobacterium tuberculosis, despite its ability to encode 15 adenylate cyclases and 10 cNMP-binding proteins. M. tuberculosis Rv3676, which we have designated CRPMt, is predicted to be a cAMP-dependent transcription factor. In this study, we characterized CRPMt's interactions with DNA and cAMP, using experimental and computational approaches. We used Gibbs sampling to define a CRPMt DNA motif that resembles the cAMP receptor protein (CRP) binding motif model for Escherichia coli. CRPMt binding sites were identified in a total of 73 p

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Miggiano, Riccardo, Giuseppe Perugino, Maria Ciaramella, et al. "Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA." Biochemical Journal 473, no. 2 (2016): 123–33. http://dx.doi.org/10.1042/bj20150833.

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Mycobacterium tuberculosis directly repairs alkylated bases in DNA through the action of OGT. We reveal new molecular details of damaged-DNA recognition and co-operative binding by MtOGT, highlighting the peculiar structural flexibility of the protein.

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Mishra, Alok K., Shivraj M. Yabaji, Rikesh K. Dubey, Ekta Dhamija, and Kishore K. Srivastava. "Dual phosphorylation in response regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation." Biochemical Journal 474, no. 24 (2017): 4119–36. http://dx.doi.org/10.1042/bcj20170596.

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The remarkable ability of Mycobacterium tuberculosis (Mtb) to survive inside human macrophages is attributed to the presence of a complex sensory and regulatory network. PrrA is a DNA-binding regulatory protein, belonging to an essential two-component system (TCS), PrrA/B, which is required for early phase intracellular replication of Mtb. Despite its importance, the mechanism of PrrA/B-mediated signaling is not well understood. In the present study, we demonstrate that the binding of PrrA on the promoter DNA and its consequent activation is cumulatively controlled via dual phosphorylation of

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Dissertations / Theses on the topic "Mycobacterium DNA Binding Protein"

1

Alvarez, Martinez Jesus Antonio. "Role of [gamma][delta]-T cells in mycobacterial infection and inflammation /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcitt?p9999268.

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Bisset, Louise Clair. "Fluorescence of a DNA-binding protein." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320129.

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Slayton, Mark D. "Protein-DNA Interactions of pUL34, an Essential Human Cytomegalovirus DNA-Binding Protein." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1533638730703166.

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Fekete, Richard Alfred. "Characterizing the protein and DNA interactions of the F plasmid DNA binding protein, TraM." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ60291.pdf.

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Goddard, C. "DNA and chromatin binding by the methyl-CpG-binding protein, MeCP2." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599452.

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In eukaryotes, methylation at CpG dinucleotides causes transcriptional repression. MeCP2 is a good candidate for a transducer of this methylation signal as it is capable of binding to methylated DNA and can repress transcription <i>in vitro</i>. This thesis describes experiments to further investigate the DNA and chromatin binding properties of MeCP2. Chapter 2 describes the subcloning, overexpression and purification of recombinant rat MeCP2 and also the purification of native MeCP2 from rat brain. The similarity in purification protocols indicates that the recombinant protein is a good model

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Andrade, Helena. "DNA Oligomers - From Protein Binding to Probabilistic Modelling." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-218709.

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This dissertation focuses on rationalised DNA design as a tool for the discovery and development of new therapeutic entities, as well as understanding the biological function of DNA beyond the storage of genetic information. The study is comprised of two main areas of study: (i) the use of DNA as a coding unit to illustrate the relationship between code-diversity and dynamics of self-assembly; and (ii) the use of DNA as an active unit that interacts and regulates a target protein. In the study of DNA as a coding unit in code-diversity and dynamics of self-assembly, we developed the DNA-Based

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Maynard, Allister J. "NMR studies of protein folding and DNA binding." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313244.

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Povey, Jane. "Structural studies of the DNA-binding protein GAL4." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385462.

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Cruickshank, Jennifer. "The DNA binding mechanism of the Epstein-Barr origin binding protein, EBNA1." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0006/MQ46091.pdf.

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Phillips, Christine M. (Christine Marie). "Relating metal binding to DNA binding in the nickel regulatory protein NikR." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57569.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Vita. Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references.<br>The concentration of transition metals within the cell must be tightly regulated. If the concentration of a given transition metal is too low the cell may not be able to perform life-sustaining processes, while high levels of metals are poisonous to the cell a

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Books on the topic "Mycobacterium DNA Binding Protein"

1

Travers, A. A. DNA-protein interactions. Chapman & Hall, 1993.

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A, Travers A., and Buckle Malcolm, eds. DNA, protein interactions: A practical approach. Oxford University Press, 2000.

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K, Docherty, ed. Gene transcription: DNA binding proteins. Wiley, 1996.

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Cruickshank, Jennifer. The DNA binding mechanism of the Epstein-Barr origin binding protein, EBNA1. National Library of Canada, 1999.

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5

Steitz, Thomas A. Structural studies of protein-nucleic acid interaction: Thesources of sequence-specific binding. Cambridge University Press, 1993.

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Tang, Shaojun. Studies on the DNA binding activity of HOX11 protein. National Library of Canada, 1994.

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Steitz, Thomas A. Structural studies of protein-nucleic acid interaction: The sources of sequence-specific binding. Cambridge University Press, 1993.

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8

Tom, Moss, and Leblanc Benoît, eds. DNA-protein interactions: Principles and protocols. 3rd ed. Humana Press, 2009.

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9

Williams, Mark C. Biophysics of DNA-protein interactions: From single molecules to biological systems. Springer, 2011.

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Kennedy, Breandán Noel. Molecular characterisation of cellular retinaldehyde binding protein: Gene regulation and protein function. University College Dublin, 1998.

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Book chapters on the topic "Mycobacterium DNA Binding Protein"

1

Naue, Natalie, and Ute Curth. "Investigation of Protein–Protein Interactions of Single-Stranded DNA-Binding Proteins by Analytical Ultracentrifugation." In Single-Stranded DNA Binding Proteins. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-032-8_8.

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Wilson, Keith, Isao Tanaka, Krzysztof Appelt, and Stephen White. "Double-Stranded DNA Binding Protein Hu." In Synchrotron Radiation in Structural Biology. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-8041-2_16.

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Hass, Cathy S., Ran Chen, and Marc S. Wold. "Detection of Posttranslational Modifications of Replication Protein A." In Single-Stranded DNA Binding Proteins. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-032-8_15.

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Fischer, Nicholas O., and Theodore M. Tarasow. "Identification and Optimization of DNA Aptamer Binding Regions Using DNA Microarrays." In Protein Microarray for Disease Analysis. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-043-0_5.

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Page, Asher N., and Nicholas P. George. "Methods for Analysis of SSB–Protein Interactions by SPR." In Single-Stranded DNA Binding Proteins. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-032-8_12.

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Fletcher, Steven, and Edward V. Prochownik. "CHAPTER 12. Small-molecule Inhibitors of Myc–Max Interaction and DNA Binding." In Protein–Protein Interaction Regulators. Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781788016544-00302.

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Zhao, Hongyu, Baolin Wu, and Ning Sun. "DNA-protein binding and gene expression patterns." In Institute of Mathematical Statistics Lecture Notes - Monograph Series. Institute of Mathematical Statistics, 2003. http://dx.doi.org/10.1214/lnms/1215091147.

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Inoue, Jin, and Tsutomu Mikawa. "Use of Native Gels to Measure Protein Binding to SSB." In Single-Stranded DNA Binding Proteins. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-032-8_13.

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Hofmann, J. F. X., and S. M. Gasser. "Protein-DNA Interaction at Yeast Replication Origins: an ARS Consensus Binding Protein." In DNA Replication: The Regulatory Mechanisms. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76988-7_17.

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McCauley, Micah J., and Mark C. Williams. "Measuring DNA–Protein Binding Affinity on a Single Molecule Using Optical Tweezers." In DNA Nanotechnology. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-142-0_21.

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Conference papers on the topic "Mycobacterium DNA Binding Protein"

1

Wong, Ka-Chun. "Data Analytics for Protein-DNA Binding Interactions." In 2015 IEEE International Conference on Systems, Man, and Cybernetics (SMC). IEEE, 2015. http://dx.doi.org/10.1109/smc.2015.278.

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Barash, Yoseph, Gal Elidan, Nir Friedman, and Tommy Kaplan. "Modeling dependencies in protein-DNA binding sites." In the seventh annual international conference. ACM Press, 2003. http://dx.doi.org/10.1145/640075.640079.

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Tariq, Sana, and Asjad Amin. "Detection of DNA - Protein Binding Using Deep Learning." In 2023 IEEE International Conference on Emerging Trends in Engineering, Sciences and Technology (ICES&T). IEEE, 2023. http://dx.doi.org/10.1109/icest56843.2023.10138842.

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Cheng, Po-Han, Hung-Yu Chen, and Hung-Yu Kao. "Protein surface search in DNA-binding protein prediction by Delaunay triangulation modeling." In 2010 International Computer Symposium (ICS 2010). IEEE, 2010. http://dx.doi.org/10.1109/compsym.2010.5685406.

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Lee, En-Shiun Annie, Kwong-Sak Leung, Ho-Yin Sze-To, Terrence Chi-Kong Lau, Man-Hon Wong, and Andrew K. C. Wong. "Discovering protein-DNA binding cores by aligned pattern clustering." In 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2014. http://dx.doi.org/10.1109/bibm.2014.6999140.

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Intze, A., M. E. Temperini, R. Polito, et al. "Mid-infrared nanospectroscopy of individual DNA-binding protein oligomers." In 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz). IEEE, 2022. http://dx.doi.org/10.1109/irmmw-thz50927.2022.9895918.

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Zhou, Weiqiang, and Hong Yan. "Prediction of DNA-binding protein based on alpha shape modeling." In 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2010. http://dx.doi.org/10.1109/bibm.2010.5706529.

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Wong, Po-Yuen, Tak-Ming Chan, Man-Hon Wong, and Kwong-Sak Leung. "Predicting Approximate Protein-DNA Binding Cores Using Association Rule Mining." In 2012 IEEE International Conference on Data Engineering (ICDE 2012). IEEE, 2012. http://dx.doi.org/10.1109/icde.2012.86.

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Chen, Qiujian, Lei Li, Kun Yang, Rong Long, and Feng Shi. "Prediction of DNA-binding protein using random forest and elastic net." In 2017 13th International Conference on Natural Computation, Fuzzy Systems and Knowledge Discovery (ICNC-FSKD). IEEE, 2017. http://dx.doi.org/10.1109/fskd.2017.8393048.

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Spuhler, Philipp, Xirui Zhang, Margo Monroe, et al. "Precise control of DNA orientation for improved functionlity in protein binding microarrays." In Nanophotonics. IEEE, 2011. http://dx.doi.org/10.1109/omems.2011.6031084.

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Reports on the topic "Mycobacterium DNA Binding Protein"

1

Hanke, Andreas. DNA Conforming Dynamics and Protein Binding. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada461014.

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Yaswen, Paul. Functional Analysis of BORIS, A Novel DNA Binding Protein. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada448330.

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Yaswen, Paul. Functional Analysis of BORIS, a Novel DNA Binding Protein. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada435433.

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Yaswen, Paul. Functional Analysis of BORIS, a Novel DNA Binding Protein. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada477978.

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Yaswen, Paul. Functional Analysis of BORIS, a Novel DNA Binding Protein. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada481004.

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Hanke, Andreas. Studies of Single Biomolecules, DNA Conformational Dynamics, and Protein Binding. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada483440.

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Hori, Roderick T. Delineation of Methyl-DNA Binding Protein Interactions in the Prostate Cancer Genome. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada588947.

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Hori, Roderick T. Delineation of Methyl-DNA Binding Protein Interactions in the Prostate Cancer Genome (PC110091). Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada610506.

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Bercovier, Herve, Raul Barletta, and Shlomo Sela. Characterization and Immunogenicity of Mycobacterium paratuberculosis Secreted and Cellular Proteins. United States Department of Agriculture, 1996. http://dx.doi.org/10.32747/1996.7573078.bard.

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Our long-term goal is to develop an efficient acellular vaccine against paratuberculosis based on protein antigen(s). A prerequisite to achieve this goal is to analyze and characterize Mycobacterium paratuberculosis (Mpt) secreted and cellular proteins eliciting a protective immune response. In the context of this general objective, we proposed to identify, clone, produce, and characterize: the Mpt 85B antigen and other Mpt immunoreactive secreted proteins, the Mpt L7/L12 ribosomal protein and other immunoreactive cellular proteins, Mpt protein determinants involved in invasion of epithelial c

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Patsialou, Antonia, and Elizabeth Moran. Characterization of the Novel DNA-Binding Activity of p270, a hSWI/SNF Protein Frequently Downregulated in Breast Cancer. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443056.

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