Academic literature on the topic 'Mycobiote intestinal'

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Journal articles on the topic "Mycobiote intestinal"

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James, Steve A., Aimee Parker, Catherine Purse, et al. "The Cynomolgus Macaque Intestinal Mycobiome Is Dominated by the Kazachstania Genus and K. pintolopesii Species." Journal of Fungi 8, no. 10 (2022): 1054. http://dx.doi.org/10.3390/jof8101054.

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The cynomolgus macaque, Macaca fascicularis, is a non-human primate (NHP) widely used in biomedical research as its genetics, immunology and physiology are similar to those of humans. They may also be a useful model of the intestinal microbiome as their prokaryome resembles that of humans. However, beyond the prokaryome relatively little is known about other constituents of the macaque intestinal microbiome including the mycobiome. Here, we conducted a region-by-region taxonomic survey of the cynomolgus intestinal mycobiota, from duodenum to distal colon, of sixteen captive animals of differin
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Cheibchalard, Thanya, Asada Leelahavanichkul, Piraya Chatthanathon, Piriya Klankeo, Nattiya Hirankarn, and Naraporn Somboonna. "Fungal microbiome in gut of systemic lupus erythematosus (SLE)-prone mice (pristane and FCGRIIb deficiency), a possible impact of fungi in lupus." PLOS ONE 19, no. 12 (2024): e0314662. https://doi.org/10.1371/journal.pone.0314662.

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The gut mycobiota (fungal microbiota) plays a crucial role in the immune system, potentially impacting autoimmune diseases such as systemic lupus erythematosus (SLE). Despite growing interest, data on intestinal fungi in SLE remain limited. This study thereby investigated the human-mimicked (mice) gut mycobiome and quantitative gut mycobiome analyses using universal fungal internal transcribed spacer 2 (ITS2) DNA next generation sequencing and real-time PCR, tracking time-series dynamics from preclinical to established SLE conditions in two SLE-prone mouse models. These models included pristan
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Chiappori, Federica, Francesca Anna Cupaioli, Arianna Consiglio, et al. "Analysis of Faecal Microbiota and Small ncRNAs in Autism: Detection of miRNAs and piRNAs with Possible Implications in Host–Gut Microbiota Cross-Talk." Nutrients 14, no. 7 (2022): 1340. http://dx.doi.org/10.3390/nu14071340.

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Intestinal microorganisms impact health by maintaining gut homeostasis and shaping the host immunity, while gut dysbiosis associates with many conditions, including autism, a complex neurodevelopmental disorder with multifactorial aetiology. In autism, gut dysbiosis correlates with symptom severity and is characterised by a reduced bacterial variability and a diminished beneficial commensal relationship. Microbiota can influence the expression of host microRNAs that, in turn, regulate the growth of intestinal bacteria by means of bidirectional host-gut microbiota cross-talk. We investigated po
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Patnaik, Supriti, Siva Sundara Kumar Durairajan, Abhay Kumar Singh, et al. "Role of Candida species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease." World Journal of Gastroenterology 30, no. 48 (2024): 5212–20. http://dx.doi.org/10.3748/wjg.v30.i48.5212.

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The gut microbiome plays a key role in the pathogenesis and disease activity of inflammatory bowel disease (IBD). While research has focused on the bacterial microbiome, recent studies have shifted towards host genetics and host-fungal interactions. The mycobiota is a vital component of the gastrointestinal microbial community and plays a significant role in immune regulation. Among fungi, Candida species, particularly Candida albicans (C. albicans ), have been extensively studied due to their dual role as gut commensals and invasive pathogens. Recent findings indicate that various strains of
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Li, Xin, Irina Leonardi, Alexa Semon, et al. "Sensing Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease." Journal of Immunology 202, no. 1_Supplement (2019): 191.3. http://dx.doi.org/10.4049/jimmunol.202.supp.191.3.

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Abstract Sensing of the gut microbiota, including fungi, regulates mucosal immunity. Whether fungal sensing in the gut can influence immunity at other body sites is unknown. Here we show that fluconazole-induced gut fungal dysbiosis has persistent effects on allergic airway disease in a house dust mite challenge model. Mice with a defined community of bacteria, but lacking intestinal fungi were not susceptible to fluconazole-induced dysbiosis, while colonization with a fungal mixture recapitulated the detrimental effects. Gut-resident mononuclear phagocytes (MNPs) expressing the fractalkine re
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Zhang, Zeming, Yining Zhang, Qixiang Yuan, et al. "A Meta-Analysis of the Human Gut Mycobiome Using Internal Transcribed Spacer Data." Microorganisms 12, no. 12 (2024): 2567. https://doi.org/10.3390/microorganisms12122567.

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The intestinal mycobiome is closely related to human health. There have been several reports investigating the association between the gut fungi and disease, but there is still a lack of overall assessment of the human gut mycobiome. Here, we performed a meta-analysis based on 2372 ITS (Internal Transcribed Spacer) data collected publicly online. We found that the mycobiome diversity of human gut fungi varies significantly across diseases by using EasyAmplicon, and these fungi are mainly composed of three genera, Saccharomyces, Candida, and Aspergillus. In addition, we performed the constructi
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Deng, Xiaofeng, Hua Li, Aimin Wu, et al. "Composition, Influencing Factors, and Effects on Host Nutrient Metabolism of Fungi in Gastrointestinal Tract of Monogastric Animals." Animals 15, no. 5 (2025): 710. https://doi.org/10.3390/ani15050710.

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Intestinal fungi, collectively referred to as mycobiota, constitute a small (0.01–2%) but crucial component of the overall intestinal microbiota. While fungi are far less abundant than bacteria in the gut, the volume of an average fungal cell is roughly 100-fold greater than that of an average bacterial cell. They play a vital role in nutrient metabolism and maintaining intestinal health. The composition and spatial organization of mycobiota vary across different animal species and are influenced by a multitude of factors, including age, diet, and the host’s physiological state. At present, qu
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Moeller, Jesper B., Irina Leonardi, Anders Schlosser, et al. "Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1." Journal of Experimental Medicine 216, no. 12 (2019): 2689–700. http://dx.doi.org/10.1084/jem.20182244.

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Host–microbiota interactions are critical in regulating mammalian health and disease. In addition to bacteria, parasites, and viruses, beneficial communities of fungi (the mycobiome) are important modulators of immune- and tissue-homeostasis. Chitin is a major component of the fungal cell wall, and fibrinogen C containing domain 1 (FIBCD1) is a chitin-binding protein; however, the role of this molecule in influencing host–mycobiome interactions in vivo has never been examined. Here, we identify direct binding of FIBCD1 to intestinal-derived fungi and demonstrate that epithelial-specific expres
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Kanj, Amjad N., and Joseph H. Skalski. "Gut Mycobiome and Asthma." Journal of Fungi 10, no. 3 (2024): 192. http://dx.doi.org/10.3390/jof10030192.

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This review explores the ‘gut–lung axis’ in asthma with a focus on commensal fungal organisms. We explore how changes to the intestinal commensal fungal community composition alter lung immune function. We comprehensively review available studies that have profiled the composition of the gut mycobiome in adults and children with asthma, and discuss mechanisms of gut–lung interactions that have been described in animal models of asthma. Studies indicate that intestinal fungal dysbiosis, such as an increased abundance of certain fungi like Candida, can elevate the risk of asthma in children and
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Zhang, Lin, Hui Zhan, Wenye Xu, Shuai Yan, and Siew C. Ng. "The role of gut mycobiome in health and diseases." Therapeutic Advances in Gastroenterology 14 (January 2021): 175628482110471. http://dx.doi.org/10.1177/17562848211047130.

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The gut microbiome comprised of microbes from multiple kingdoms, including bacteria, fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut “mycobiome”) play an important role in host immunity and inflammation. Advances in next generation sequencing methods to study the fungi in fecal samples and mucosa tissues have expanded our understanding of gut fungi in intestinal homeostasis and systemic immunity in health and their contribution to different human diseases. In this review, the current status of gut mycobiome in health, early life, and different diseases includi
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Dissertations / Theses on the topic "Mycobiote intestinal"

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Cornu, Marjorie. "Mycobiome et maladies inflammatoires chroniques de l'intestin : Impact de la dysbiose sur l'inflammation intestinale et le processus fibrotique." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. https://pepite-depot.univ-lille.fr/ToutIDP/EDBSL/2024/2024ULILS010.pdf.

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Introduction. Alors que le mycobiote représente une part quantitative négligeable, en apparence, du microbiote intestinal, les preuves de son rôle dans les maladies inflammatoires chroniques de l’intestin, et notamment la maladie de Crohn (MC), sont croissantes. Ce travail avait pour objectif d’évaluer l’impact de Candida albicans et Saccharomyces cerevisiae sur l’inflammation et la fibrose intestinale (FI), mais également sur la production des anticorps anti-S. cerevisiae (ASCA), reconnaissant des séquences oligomannosidiques de faible degré de polymérisation ayant un résidu α,1-3 mannose ter
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Hoarau, Gautier. "Caractérisation du mycobiome intestinal et fécal chez les patients atteints de maladie de Crohn, et leurs parents sains du premier degré." Thesis, Lille 2, 2016. http://www.theses.fr/2016LIL2S033/document.

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Introduction : La maladie de Crohn (MC), maladie inflammatoire chronique intestinale, est une maladie multifactorielle, d’origine inconnue. La dysbiose bactérienne a été largement évoquée dans la pathogénèse de la MC. Notre objectif était de caractériser la flore fongique, conjointement à la flore bactérienne au cours de formes familiales de MC.Méthodes: Nous avons utilisé une plateforme de séquençage à haut débit pour caractériser la flore fongique et bactérienne fécale, échantillonnée dans 9 familles multiplexes atteints de MC (20 patients, et 28 sujets sains apparentés), et 4 familles contr
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Lussac-Sorton, Florian. "Effet des thérapies protéiques sur l’axe intestin-poumon dans la mucoviscidose." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0428.

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La mucoviscidose est une pathologie multi-organes dont la progression est principalement déterminée par les atteintes respiratoires et digestives. L’avènement des modulateurs de CFTR en a révolutionné le pronostic au cours de la dernière décennie. Les perturbations du microbiote et du mycobiote ont été bien décrites dans la mucoviscidose, ainsi que dans une moindre mesure les connexions inter-organes définissant l’axe intestin-poumon. Cependant les données sont encore lacunaires concernant l’impact des thérapies protéiques sur le myco-microbiote.Le protocole LUM-IVA-BIOTA est une étude nationa
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Borges, Francis Moreira. "Caracterização de fungos intestinais cultiváveis e avaliação da estrutura da micobiota intestinal humana de indivíduos obesos, com sobrepeso e eutróficos." Universidade Federal de Juiz de Fora (UFJF), 2018. https://repositorio.ufjf.br/jspui/handle/ufjf/6772.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2018-05-17T15:27:41Z No. of bitstreams: 0<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2018-05-22T11:42:00Z (GMT) No. of bitstreams: 0<br>Made available in DSpace on 2018-05-22T11:42:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-03<br>Os fungos têm um papel complexo no trato intestinal, influenciando diretamente na saúde e na doença e sua disbiose pode contribuir para a obesidade. O objetivo deste estudo foi avaliar a diversidade de fungos da microbiota intestinal humana entre indi
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