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Dissertations / Theses on the topic 'Mycology'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Olsson, Johan. "Modern methods in cereal grain mycology /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5792-0.pdf.

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2

Donnison, Louise. "Mycology of haymeadows under management change." Thesis, Aberystwyth University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287116.

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Management improvements have caused a decline in plant species diversity in traditionally managed haymeadows. The aim of this study was examine the effects and causes of management improvements on the soil microbialocmmunity with particular emphasis on the fungal component. A seasonal study of 3 sites showed that management improvements to haymeadows consistently reduced soil microbial biomass C, but had no effect on dehydrogenase activity and basal respiration. Management improvements to these sites also caused a significant reduction in VAM spore numbers, soil fungal biomass, measured as soi

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3

Smith, David. "The evaluation and development of techniques for the preservation of living filamentous fungi." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/38164.

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4

Dyer, Paul Stanley. "Perithecial development in Nectria haematococca mating population VI." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386915.

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5

Marathe, Sudhir Vasant. "Targeted mutagenesis, structure and function of a new gene required for acetate utilisation in Neurospora crassa." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315923.

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6

Wadekar, Rekha Vishwas. "Regulation of proteinase activities in basidiomycete wood decay fungi." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260749.

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7

Furlaneto, Marcia Cristina. "Genetical studies on invertase in Aspergillus nidulans." Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335855.

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8

Belfield, Graham Paul. "The role of elongation factor 3 in yeast protein synthesis." Thesis, University of Kent, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358842.

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9

Rozycka, Magdalena. "Use of biochemical and immunological methods to distinguish arbuscular mycorrhizal fungi (AMF)." Thesis, University of Kent, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387019.

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10

Galbraith, Daniel Norman. "Molecular and immunological analysis and detection of the forest pathogen Heterbasidion annosum." Thesis, University of Abertay Dundee, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359300.

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11

Hamer, Alison. "Dynamics of fungal growth in stored grain." Thesis, Cranfield University, 1993. http://dspace.lib.cranfield.ac.uk/handle/1826/11025.

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Large and small-scale respirometry apparatus were developed and optimised to measure the respiration of 25 g and 10 kg seed samples stored under a range of environmental conditions, from 0.80 to 0.95 water activity (~) and 15 to 35°C in all combinations. Respiration of wheat and barley grains was greater, than that of rapeseed and linseed. Oxygen consumption was linear with time for naturally contaminated wheat grain over the range 0.90-0.95 aw/15- 25°C and 0.80-0.95 ~/30-35°C, in sterile wheat grain at 0.90 ~125°C, and in barley and rapeseed at 0.90 ~120°C but was non-linear in wheat grain at

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12

Wynn, James Patrick. "The intermediary metabolism of Fusarium moniliforme." Thesis, University of Hull, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262424.

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13

Gaskell, Tracey Anne. "Development and stromal structure in Daldinia concentrica (Bolt.:Fr.) (Ces. & De Not.)." Thesis, Liverpool John Moores University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262110.

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14

Johnstone, Iain Lindsay. "Transformation of Aspergillus nidulans." Thesis, University of Glasgow, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313341.

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15

Russell, Ian Douglas. "NOP3, a protein involved in pre-ribosomal RNA processing." Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239708.

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16

Прімова, Людмила Олександрівна, Людмила Александровна Примова, Liudmyla Oleksandrivna Primova, Юлія Сергіївна Моторна, Юлия Сергеевна Моторная та Yuliia Serhiivna Motorna. "Азотистий склад біомаси мукорового гриба Blakeslea trispora". Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/5997.

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17

Evans, Neal. "A study of the interactions between Alternaria linicola and linseed." Thesis, University of Glasgow, 1996. http://theses.gla.ac.uk/39033/.

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The principal aim of the study was to further the knowledge of the interaction between Alternaria linicola and the host plant linseed (Linum usitatissimum). A novel detached cotyledon in vitro bioassay was developed to allow the quantification of disease resistance of Linum material to A. linicola. Differences were apparent between the disease response scores of four linseed varieties when tested with seven isolates of the pathogen which differed in aggressiveness. However, there was no significant difference between the disease response scores of the varieties and no change in the ranking of

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18

García, Daiana. "Predictive mycology and use of natural antifungals to prevent the mycotoxin food hazard." Doctoral thesis, Universitat de Lleida, 2012. http://hdl.handle.net/10803/93074.

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Filamentous moulds may cause spoilage in raw materials, foods and feeds. Some of them synthesize mycotoxins which are a risk for human and animal health. For this reason, from the food safety point of view, only mycotoxins, as chemical hazards, are important. Nevertheless, despite the absence of direct correlation between mould growth and mycotoxins production, the prevention of fungal growth in raw materials and foods leads invariably to the prevention of mycotoxins presence. Due to the fact that moulds can contaminate foods from raw materials till end products, different strategies could be

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19

Boddy, Lynn M. "Regulation and molecular cloning of an invertase gene from Aspergillus niger." Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336021.

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20

Schofield, David Alexander. "Regulation of chitin synthesis in Candida albicans." Thesis, University of Aberdeen, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259699.

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The study of the regulation of chitin synthesis in the pathogen <i>Candida albicans</i> is a challenging field. It not only offers a possibility of a better understanding of the dimorphic transition but also may help in the development of an effective antifungal. The suggestion that the regulation of cell wall synthesis may be closely coupled to the turgor pressure of the fungus has been investigated. The synthesis of chitin by the enzyme chitin synthase was studied under conditions of osmotic stress. Mixed membrane fractions from protoplasts of <i>C.albicans</i> incubated in medium of low osm

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21

Abarca, Salat Ma Lourdes. "Contribución al estudio de la micoflora presente en el hábitat de animales aparentemente sanos." Doctoral thesis, Universitat de Barcelona, 1986. http://hdl.handle.net/10803/672797.

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La célula animal puede ser parasitada por un amplio grupo de hongos miceliares y levaduras que desencadenan procesos clínicos característicos: dermatofitosis, micosis profundas, etc. Estos microorganismos han sido objeto de estudio por parte de numerosos investigadores, pero son escasos los trabajos que hacen referencia a la micoflora presente en animales sin afección fúngica alguna. La presencia de todo tipo de hongos en la piel y plumas de los animales está directamente relacionada con el contenido en propágulos fúngicos viables del hábitat propio de cada animal: atmósfera, sue

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22

Firacative, Ropero Sandra Carolina. "Characterization of the human pathogenic species Cryptococcus neoformans and Cryptococcus gattii with a special emphasis on emerging molecular types within C. gattii." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/12738.

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The rising incidence of cryptococcosis, a life-threatening fungal infection affecting both immunocompromised and immunocompetent humans and animals, along with the emergence of outbreaks of infection, highlight the need of an increased and constant vigilance of its etiological agents Cryptococcus neoformans and C. gattii. The initial part of this PhD thesis evaluates MALDI-TOF MS and hyperbranched rolling circle PCR as two new alternative methodologies for the rapid and accurate identification of these two species and their major molecular types. The second part shows the utility of the insect

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23

Bowen, Suzanne. "Stress and stationary phase characteristics in cell wall defective strains of Saccharomyces cerevisiae." Thesis, University of Bath, 2000. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341199.

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24

Aldars, García Laila. "Predictive mycology as a tool for controlling and preventing the aflatoxin risk in postharvest." Doctoral thesis, Universitat de Lleida, 2017. http://hdl.handle.net/10803/418806.

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Les aflatoxines són potents carcinògens que representen una amenaça significativa per a la salut humana. La incidència d'aquestes micotoxines en els aliments és alta, de manera que el seu control i prevenció són necessaris en la indústria alimentària. El desenvolupament de models predictius apropiats que ens permetin predir el creixement fúngic i la producció de micotoxines és de gran utilitat com a eina per controlar, predir i prevenir el risc de micotoxines en aliments. És important que els models predictius siguin capaços d'explicar les condicions ambientals que es troben al llarg de la cad

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25

Guevara-Guerrero, Gonzalo. "Biological studies of shiitake logs and associated mycoflora in the Virginia highlands." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-08142009-040430/.

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26

Lavine, Ingrid Nadean. "Characterization of an Arsenate-Reducing Bacterium Strain NP4, Isolated from Groundwater in Northport, Maine." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/LavineIN2004.pdf.

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27

Newton, Giles H. "Investigation of the molecular mechanisms that regulate the qut gene cluster of Aspergillus nidulans." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320026.

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28

Chaure, Pushpalata Trimbak. "A regulatory role for acetyl-CoA synthetase (acu-5) in Neurospora crassa." Thesis, University of Reading, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239059.

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29

Cox, Philip William. "Application of image analysis to fungal fermentations." Thesis, University of Birmingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364884.

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30

ICENHOUR, CRYSTAL RENEE PERRY. "EXPERIMENTAL EVIDENCE FOR COMPETITIVE COEXISTENCE OF TWO SPECIES OF PNEUMOCYSTIS WITHIN RAT LUNGS." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1012244966.

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31

Gilfillan, Gregor D. "Virulence and signal transduction of hypha formation in Candida albicans." Thesis, University of Aberdeen, 1999. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU112191.

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The aims of this work were to investigate the signal transduction pathways controlling the yeast-hyphal morphological transition of Candida albicans, and to gain a clearer understanding of the importance of hyphal formation of the virulence of this organism. The work can be divided into two areas. Firstly, the recently discovered species Candida dubliniensis, the only species in addition to C. albicans capable of forming true non-constricted hyphae, was examined in comparison to C. albicans to compare their virulence capability in vitro and in vivo. The two species were compared with respect t

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32

Low, Gordon Alister. "An investigation of selected effects of environment on the dry rot fungus, Serpula lacrymans." Thesis, Abertay University, 2000. https://rke.abertay.ac.uk/en/studentTheses/5f450e84-358d-4c10-b234-733cf2e67d4f.

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Comparisons were made between the sensitivities of unique ‘wild’ isolates and domestic isolates of the dry rot fungus, <i>Serpula lacrymans</i>, to temperature, water potential and pH. Comparisons were also made between their capacities of timber decay. The ‘wild’ Himalayan isolates displayed slightly less marked sensitivities to high and low temperature and lowered water potential, yet the isolates were equally tolerant of pH. In general, the linear growth rates of the domestic isolates proved to be twice those of the ‘wild’ Himalayan set, whereas little variation occurred between their rates

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33

Carlisle, Diane Jean. "The diversity of the Phytophthora infestans population in Northern Ireland." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322769.

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34

Lyne, Michael Harvey. "Cloning and characterisation of a meiosis-specific gene, pck1, from the fission yeast Schizosaccharomyces pombe." Thesis, University of Exeter, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260618.

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35

Kasuga, Takao. "Molecular probes for identification of intersterility groups of the wood rot fungus Heterobasidion annosum." Thesis, University of Aberdeen, 1995. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU068827.

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Heterobasidion annosum (Fr.) Bref., is a pathogenic hymenomycete which causes white-rot of coniferous trees throughout temperate regions of the Northern Hemisphere. The fungus can be divided into three intersterility groups (IS-groups) in Europe and two IS-groups in North America based on in vitro sexual compatibility and, loosely, on host tree preference. European P, S and F IS-groups prefer pine, spruce and fir respectively, and North American P and S groups prefer pine and fir respectively. This work describes the identification of discriminating characters which reflect underlying genetic

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36

Barker, Bridget M. "POPULATION GENETICS AND GENOMICS OF COCCIDIOIDES IMMITIS AND COCCIDIOIDES POSADASII." Diss., The University of Arizona, 2009. http://hdl.handle.net/10150/193909.

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The goal of my dissertation research is to elucidate the population structure of two understudied but increasingly important fungal pathogens of humans. Coccidioides immitis and C. posadasii cause the disease coccidioidomycosis (Valley fever). These fungi occur in the soil of the desert regions of North and South America. Although studied for over 100 years, the primary host, ecological niche, and sexual cycle of Coccidioides spp. still remain unknown. Understanding the population structure of these fungi will permit identification of fundamental aspects of their ecology and allow researchers

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37

Sindle, Astrid Elizabeth. "Evaluation of the effect of morphological control of dimorphic Mucor circinelloides on heterologous enzyme production." Thesis, Link to the online version, 2006. http://hdl.handle.net/10019/1207.

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38

Vandegrift, Andrew. "Ecological Roles of Fungal Endophytes." Thesis, University of Oregon, 2016. http://hdl.handle.net/1794/20401.

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Endophytic fungi live within tissues of plant hosts without causing symptoms of disease. These fungi are broadly split into the taxonomically and ecologically cohesive Clavicipitaceous endophytes, which infect grasses, and the taxonomically diverse non-Clavicipitaceous endophytes, which are found in nearly all plants and have diverse ecological strategies. My dissertation has two sections: Section A investigates the intersection of Clavicipitaceous endophyte ecology with other ecological theory, including invasion ecology (Chapter II) and community ecology and climate change (Chapter III); Sec

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39

Caitano, Cinthia Elen Cardoso. "PATOGENICIDADE DE Lecanicillium fungicola EM Agaricus bisporus /." Jaboticabal, 2020. http://hdl.handle.net/11449/192648.

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Orientador: Diego Cunha Zied<br>Resumo: O fungo Lecanicillium fungicola é um importante patógeno no cultivo de Agaricus bisporus, apresentando diversos sintomas e perdas de produção. O objetivo do trabalho foi avaliar interações in vivo e in vitro dos fungos Lecanicillium fungicola e Agaricus bisporus. Os experimentos in vitro foram feitos utilizando discos de micélio do patógeno e composto colonizado pelo A. bisporus. O composto colonizado também foi utilizado para a frutificação de cogumelos tanto em tamanho menor em placas de petri como em maior quantidade. Foram aplicados quatro suspensões

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40

Bonetto, Valentina. "From cell to organism: an overview of responses to simulated hypergravity and microgravity." Doctoral thesis, Università del Piemonte Orientale, 2022. http://hdl.handle.net/11579/144698.

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41

Talarico, Claudio. "Leveduras em trato intestinal de população pediátrica hospitalizada." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-22052015-171831/.

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Nas últimas décadas, houve aumento progressivo das infecções hospitalares por leveduras principalmente, do gênero Candida. A fonte de infecção pode ser endógena ou exógena, desde que esporos unicelulares de leveduras, permanecem viáveis por meses sobre superfícies bióticas ou abióticas. Diversas espécies de leveduras são encontradas em pele e mucosas de indivíduos sadios. Em estado saprofítico ainda, as leveduras encontram-se no trato gastrintestinal humano mas, a relação entre a presença desses microorganismos e sua patogenicidade está associada a diversos fatores predisponentes, tais como: n

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42

Bet, Diego Leonardo. "Padrões de dermatoscopia da placa ungueal nas onicomicoses." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5133/tde-23092015-115531/.

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INTRODUÇÃO: Onicomicose é a infecção fúngica das unhas e é considerada a onicopatia mais frequente em adultos. Representa até 50% das lesões ungueais, sendo necessária confirmação diagnóstica com exame complementar que demostre a presença do fungo na unha, sendo o exame micológico direto e a cultura para fungos os mais utilizados. A dermatoscopia é um exame não invasivo, rápido e de baixo custo cujos padrões para onicomicose relatados na literatura em estudos retrospectivos chegam a 100% de sensibilidade e especificidade. Deste modo realizamos um estudo prospectivo para comparar a dermatoscopi

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43

Nicolau, Manterola Felipe. "Hydrocarbon and insecticide induction of Beauveria bassiana catalysis of organosulfur compounds." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/3151.

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Catalysts are utilized in 80% of all chemical synthesis operations. The industrial catalysts primarily used in oxidation reactions are highly polluting and expensive metal catalysts. Enzymes and whole cell biocatalysts are used to a lesser extent. Nowadays, several industrial sectors are developing bio-based technologies to reduce the high costs and environmental impact of traditional chemical processes. However, these applications are limited by the challenge of developing economically competitive biologically based systems. The key for adopting these sustainable advancements is the developme

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44

Hérivaux, Anaïs. "Les récepteurs histidine kinases : structure et distribution chez les eucaryotes et caractérisation fonctionnelle chez l’espèce Scedosporium apiospermum rencontrée au cours de la mucoviscidose." Thesis, Angers, 2018. http://www.theses.fr/2018ANGE0030.

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Les histidine kinases (HKs) représentent une vaste famille de protéines impliquées dans la perception des signaux environnementaux chez les bactéries, les champignons et les plantes. Ces protéines joueraient notamment un rôle majeur dans l’adaptation aux stresses, mais aussi dans la virulence de nombreux micro-organismes procaryotes et eucaryotes. Si les HKs sont à présent bien connues chez les bactéries et les plantes, tant sur un plan structural que fonctionnel, les connaissances concernant ces protéines chez les autres clades de l’arbre du vivant demeurent plus que fragmentaires. C’est ains

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45

Thomas, Daniel. "Hitchhiking in the Canopy: Ecological Patterns of Forest Mycobiomes." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23141.

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The fungal microbiome, or “mycobiome” of plants is diverse and important to host health, but the fluxes of fungi among plant hosts and with the surrounding environment are poorly understood. In chapter two, we employed sterile culture techniques and spatial sampling to examine leaves as possible vectors for transfer of their endophytic fungi from the canopy to substrate on the forest floor, as predicted by the Foraging Ascomycete hypothesis. Some foliar endophytic fungal species are also present as wood-decomposing fungi on the forest floor, that transfer of mycelium across t

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46

Hamandjian, Adrien. "Of content space and time : Characterization of secretory vesicles in the fungal phytopathogen Botrytis cinerea." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10308.

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Du monde bactérien aux neurones, l'élongation cellulaire polarisée se retrouve dans tous les règnes du vivant. Il s’agit d'une croissance unidirectionnelle qui est particulièrement marquée chez les champignons filamenteux, dont elle est l’une des caractéristiques majeures de leur règne. L’élongation des hyphes fongiques repose sur l’extension coordonnée, à leur extrémité seulement, de la membrane plasmique et de la paroi qui l'entoure. Cette extension est alimentée par l’exocytose de vésicules de sécrétion apportant des lipides à la membranes plasmique et les enzymes membranaires et solubles n

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47

Voltan, Aline Raquel [UNESP]. "Determinação de genes/proteínas endossomais em Paracoccidioides brasiliensis e em macrófagos infectados e não infectados." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/103858.

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Made available in DSpace on 2014-06-11T19:32:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-03-01Bitstream added on 2014-06-13T21:05:08Z : No. of bitstreams: 1 voltan_ar_dr_arafcf.pdf: 1013360 bytes, checksum: 7a427a197309b3a1913694635297ee6e (MD5) Bitstreams deleted on 2015-05-25T13:05:07Z: voltan_ar_dr_arafcf.pdf,. Added 1 bitstream(s) on 2015-05-25T13:05:43Z : No. of bitstreams: 1 000715398_20160301.pdf: 174801 bytes, checksum: 8a2d22fd4d7938bc5ecd9d9d0fdd4b6c (MD5) Bitstreams deleted on 2016-03-02T17:37:22Z: 000715398_20160301.pdf,. Added 1 bitstream(s) on 2016-03-02T17:38

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48

Filho, Renato Evando Moreira. "Micologia forense: a dinÃmica da microbiota fÃngica na investigaÃÃo do perÃodo post mortem." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=2981.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>With developing of forensic observations, certain species of insects and microorganisms were described as indicators of periods of the degradation of the body. However, the literature is still scarce in the field of Forensic Mycology. It was investigated the microbiological characteristics of fungi presence in the post mortem change, as well as, it esteemed the value of the mycology exams in the study. 400 collections was accomplished in 60 human bodies (34 of the bloated stage, 06 of the putrefaction stage and 20 of the skeletoniz

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49

Ferreira, Ari José Scattone. "Regulação da resposta transcricional a estresses ambientais em fungos: análise de \"microarrays\" de cDNAs de Trichoderma reesei." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-14122006-114540/.

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A grande diversidade de organismos que hoje encontramos em nosso planeta se deve à adaptação às diferentes condições ambientais de cada nicho ecológico existente e à resposta adaptativa originária das mudanças dessas condições. Pode-se considerar que a etapa inicial do processo de adaptação seja a reprogramação da expressão gênica dum organismo como resposta imediata a uma nova condição ambiental. De fato parte do genoma de todos os organismos é dedicada à codificação de proteínas relacionadas ao controle dos efeitos nocivos criados por diferentes tipos de estresse como choque térmico, ou osmó

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Voltan, Aline Raquel. "Determinação de genes/proteínas endossomais em Paracoccidioides brasiliensis e em macrófagos infectados e não infectados /." Araraquara, 2013. http://hdl.handle.net/11449/103858.

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Abstract:

Orientador: Maria José Soares Mendes Giannini<br>Coorientador: Ana Marisa Fusco Almedia<br>Banca: Gil Benard<br>Banca: Marcelo Pelajo Machado<br>Banca: Christiane Pienna Soares<br>Banca: Raquel Mantuaneli Scarel Caminaga<br>Resumo: Os fungos dimórficos, Paracoccidioides brasiliensis (espécies cripticas S1, PS2, PS3) e Paracoccidioides lutzii (Pb01-like espécies), são agentes da paracoccidioidomicose (PCM), doença granulomatosa crônica, endêmica na América Latina, principalmente no Brasil. A doença apresenta grande variedade de manifestações clínicas, desde formas localizadas até disseminadas e

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