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1

Simecka, Jerry, та Adam Odeh. "CD4+CD25+ T regulatory cells dampen inflammatory responses in murine mycoplasma pneumonia and are associated with promotion of IL-17 AND IFN-γ production, but not IL-10 or TGF-β. (P3055)". Journal of Immunology 190, № 1_Supplement (2013): 187.3. http://dx.doi.org/10.4049/jimmunol.190.supp.187.3.

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Abstract Mycoplasmas cause respiratory diseases characterized by persistent infection and chronic airway inflammation. Mycoplasma lung disease is immunopathologic, with Th cells determining disease severity and resistance to infection. Th2 cell responses promote immunopathology; Th1 cells confer resistance to infection. However, little is known about the role of Treg cells in mycoplasma respiratory diseases. We hypothesized Treg cells control the severity of the inflammatory lesions and may also promote persistence of infection, as found in other diseases. To examine this, mice, given anti-CD2
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2

Huminer, David, Rudi Levy, Silvio Pitlik, and Zmira Samra. "Mycoplasma and Chlamydia in Adenoids and Tonsils of Children Undergoing Adenoidectomy or Tonsillectomy." Annals of Otology, Rhinology & Laryngology 103, no. 2 (1994): 135–38. http://dx.doi.org/10.1177/000348949410300209.

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The prevalence of mycoplasmal and chlamydial infection was assessed in 83 children undergoing adenoidectomy, tonsillectomy, or both procedures for recurrent adenotonsillitis or obstructive symptoms. Throat smears (surface specimens) and minced adenoids and tonsils (core specimens) were cultured for Mycoplasma spp and for Chlamydia spp. Isolation rates in adenoidal specimens were as follows: Mycoplasma hominis, surface 7.1%, core 2.9%; and Ureaplasma urealyticum, surface 1.4%, core 2.9%. Mycoplasma hominis was also found in tonsillar specimens: surface 14.3%, core 20%. Chlamydia trachomatis was
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3

Santos, Débora Ferreira dos, Arleana do Bom Parto Ferreira de Almeida, Mayara Aparecida Araujo Cayuela, et al. "Frequency of Mycoplasma haemocanis infection in dogs of Cuiaba, Mato Grosso, Brazil." Semina: Ciências Agrárias 40, no. 6Supl3 (2019): 3749. http://dx.doi.org/10.5433/1679-0359.2019v40n6supl3p3749.

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Haemotropic mycoplasmas are pleomorphic, epicellular, gram-negative bacteria, which infect red blood cells. In dogs, the acute phase of this infection may lead to haemolytic anaemia potentially precipitated by splenectomy, or by immunosuppressive drugs or diseases; however, in cases of chronic infection, the signs are inapparent. Molecular techniques and microscopic observation are the most commonly used methods to diagnose mycoplasma infection, though studies about haemotropic mycoplasma infections in dogs from Cuiabá, capital of Mato Grosso, Brazil are scarce. The objective of this study was
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4

Feng, Shaw-Huey, Shien Tsai, Jose Rodriguez, and Shyh-Ching Lo. "Mycoplasmal Infections Prevent Apoptosis and Induce Malignant Transformation of Interleukin-3-Dependent 32D Hematopoietic Cells." Molecular and Cellular Biology 19, no. 12 (1999): 7995–8002. http://dx.doi.org/10.1128/mcb.19.12.7995.

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ABSTRACT 32D cells, a murine myeloid cell line, rapidly undergo apoptosis upon withdrawal of interleukin-3 (IL-3) supplement in culture. We found that 32D cells, if infected by several species of human mycoplasmas that rapidly activated NF-κB, would live and continue to grow in IL-3-depleted culture. Mycoplasma-infected cells showed no evidence of autocrine production of IL-3. Pyrrolidine dithiocarbamate (PDTC) blocked activation of NF-κB and led to prominent cell death. Heat-killed mycoplasmas or mycoplasmal membrane preparations alone could support continued growth of 32D cells in culture wi
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5

Geppe, N. A., N. A. Krylova, I. V. Rakovskaia, et al. "Improvement of control methods of treatment of mycoplasma infection in children with bronchial asthma." Russian Journal of Allergy 9, no. 3 (2012): 27–31. http://dx.doi.org/10.36691/rja701.

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Background. Improvement of control methods of treatment of mycoplasma infection in children with bronchial asthma. Methods. 52 children from 1 to 4 years old with bronchial asthma who had mycoplasma antigens in the blood were examined before treatment of mycoplasma infection, 15 patients were examined in 1,5 months after treatment. Reaction of aggregate-hemagglutination, immunofluorescence assay and the reaction of the polymerase chain reaction (PCR) were used for detection of mycoplasmas’ antigens and DNA. Results. In reaction of aggregate-hemagglutination Mycoplasma pneumoniae (Mpn) was dete
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6

Willi, Barbara, Felicitas S. Boretti, Marina L. Meli, et al. "Real-Time PCR Investigation of Potential Vectors, Reservoirs, and Shedding Patterns of Feline Hemotropic Mycoplasmas." Applied and Environmental Microbiology 73, no. 12 (2007): 3798–802. http://dx.doi.org/10.1128/aem.02977-06.

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ABSTRACT Three hemotropic mycoplasmas have been identified in pet cats: Mycoplasma haemofelis, “Candidatus Mycoplasma haemominutum,” and “Candidatus Mycoplasma turicensis.” The way in which these agents are transmitted is largely unknown. Thus, this study aimed to investigate fleas, ticks, and rodents as well as saliva and feces from infected cats for the presence of hemotropic mycoplasmas, to gain insight into potential transmission routes for these agents. DNA was extracted from arthropods and from rodent blood or tissue samples from Switzerland and from salivary and fecal swabs from two exp
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7

Hussain, Althaf I., William Lane M. Robson, Robin Kelley, Tanya Reid, and J. David Gangemi. "Mycoplasma penetrans and Other Mycoplasmas in Urine of Human Immunodeficiency Virus-Positive Children." Journal of Clinical Microbiology 37, no. 5 (1999): 1518–23. http://dx.doi.org/10.1128/jcm.37.5.1518-1523.1999.

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Urine samples from children with human immunodeficiency virus (HIV) infection and healthy controls were examined for mycoplasmas by culture. Standard biochemical assays, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and PCR (16S and 16S-23S spacer rRNA region) were used for identification of isolates. Mycoplasmas were identified from 13 (87%) of 15 HIV-positive patients and 3 (20%) of 15 HIV-negative control patients. The frequency and type of mycoplasma varied with the severity of HIV infection.Mycoplasma penetrans, Mycoplasma pirum,Mycoplasma fermentans, and Mycoplasma genitaliu
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8

Novikova, L. N., and A. E. Taraskina. "Laboratory diagnostics of urogenital mycoplasma colonization and infection." Journal of obstetrics and women's diseases 51, no. 4 (2021): 68–72. http://dx.doi.org/10.17816/jowd91131.

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The paper presents data on the possibilities of determining urogenital mycoplasmas (Mycoplasma hominis and Ureaplasma urealyticum) using some variants of culture and PCR methods. The scheme of cultural studies in full is given, with the help of which high specificity and sensitivity indicators are achieved. The proposed research algorithm for detecting Mycoplasma hominis and Ureaplasma urealyticum, based on the use of culture and PCR methods as complementary.
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9

Ndoye, Aissatou SOW, Papa Aly Thiam GUEYE, Cheikh FAYE, et al. "Prevalence and Antimicrobial Susceptibility of Mycoplasma hominis and Ureaplasma Species among Women in Dakar." Microbiology Research Journal International 35, no. 1 (2025): 31–39. https://doi.org/10.9734/mrji/2025/v35i11533.

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Introduction: Genital mycoplasmas, which cause infections of the lower reproductive tract in women, are a major cause of morbidity and complications. The aim of this study was to determine the prevalence of mycoplasma infections and the antibiotic susceptibility profile among women in Dakar. Material and methods: We conducted a retrospective descriptive study over a four-year period, from 02 January 2018 to 31 December 2021. The study population consisted of women referred to the microbiology laboratory at Military Hospital of Ouakam for genital mycoplasma testing. The Mycoplasma IES kit was u
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Saeed, Dunya, and Naseir Badawi. "<b>Molecular study and phylogenetic analysis of hemotropic <i>Mycoplasma</i> in Baghdad province, Iraq</b>." Open Veterinary Journal 14, no. 12 (2024): 3417. https://doi.org/10.5455/ovj.2024.v14.i12.26.

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Background: Hemotrophic Mycoplasmas (HMs) are uncultivable, pleomorphic, very small epicellular, and like another Mycoplasma species lacking a cell wall. These pathogens damage and alter the erythrocytes by invading or parasitizing their surface, which can lead to persistent infections and complications. The most common hemotrophic Mycoplasmas species in dogs are Candidatus Mycoplasmas haematoparvum (CMhp), and Mycoplasma haemocanis (Mhc). Aim: The study aimed to detect infectious rates of hemotrophic Mycoplasma infections in dogs by molecular assay from Baghdad province for the first time. Me
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11

Lynch, Michael, Trevor K. Taylor, Pádraig J. Duignan, et al. "Mycoplasmas in Australian fur seals (Arctocephalus pusillus doriferus): identification and association with abortion." Journal of Veterinary Diagnostic Investigation 23, no. 6 (2011): 1123–30. http://dx.doi.org/10.1177/1040638711425699.

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Bacteria from the genus Mycoplasma are common inhabitants of the respiratory, gastrointestinal, and genital tracts of mammals. The understanding of the pathological significance of mycoplasmas in seals is poor, as few studies have utilized the specific culture techniques required to isolate these bacteria. The current study surveyed for the Mycoplasma species present in Australian fur seals ( Arctocephalus pusillus doriferus) and investigated the association between infection and pathology. Mycoplasmas were found in the nasal cavities of 55/80 (69%) of apparently healthy individuals. Isolates
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12

Vesic, Sonja, Jelica Vukicevic, Eleonora Gvozdenovic, Dusan Skiljevic, Slobodanka Janosevic, and Ljiljana Medenica. "Chlamydia trachomatis and urogenital mycoplasms in nonconococcal urethirits in men." Medical review 63, no. 1-2 (2010): 47–50. http://dx.doi.org/10.2298/mpns1002047v.

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Introduction. Nongonococcal urethritis is the most common sexually transmitted infection in men, with vast majority of the etiological agents such as Chlamydia trachomatis, followed by urogenital mycoplasmas. The aim of this study was to determine the prevalence of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in nongonococcal urethritis in men, and to examine infections associated with these agents. Material and methods. 299 sexually active, heterosexual men with nongonococcal urethritis were included into the study. Urethral samples were taken with a dacron swab placed
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13

Lobová, Dana, Jarmila Konvalinová, Iveta Bedáňová, Zita Filipejová, and Dobromila Molinková. "Infections of cats with blood mycoplasmas in various contexts." Acta Veterinaria Brno 90, no. 2 (2021): 211–19. http://dx.doi.org/10.2754/avb202190020211.

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Haemotropic microorganisms are the most common bacteria that infect erythrocytes and are associated with anaemia of varying severity. The aim of this study was to focus on the occurrence of Mycoplasma haemofelis, Mycoplasma haemominutum, and Mycoplasma turicensis in cats. We followed infected individuals’ breeding conditions, age, sex, basic haematological indices, and co-infection with one of the feline retroviruses. A total of 73 cats were investigated. Haemoplasmas were detected by PCR and verified by sequencing. Haematology examination was performed focusing on the number of erythrocytes,
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14

Carneiro, Filipe T., Marcela C. Scalon, Gabrielle Amorim, et al. "Hemoplasma infection in wild captive carnivores." Pesquisa Veterinária Brasileira 40, no. 4 (2020): 293–99. http://dx.doi.org/10.1590/1678-5150-pvb-6407.

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ABSTRACT: Hemoplasmas are bacteria able to adhere themselves loosely to the plasma membrane of erythrocytes and may parasitize several species of mammals. There are three known species of hemoplasmas that parasitize domestic and wild cats: Mycoplasma haemofelis, ‘Candidatus Mycoplasma haemominutum’ and ‘Candidatus Mycoplasma turicensis’. Dogs are infected by at least two species of hemoplasmas: ‘Candidatus Mycoplasma haematoparvum’ and Mycoplasma haemocanis. The hemoplasmoses are very important in veterinary clinics, either because of its worldwide distribution and severity of clinical signs,
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15

Raj, D. Sheth, J. Goulden Keith, and E. Pryse-phillips William. "The Focal Encephalopathies Associated with Mycoplasma Pneumoniae." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 20, no. 4 (1993): 319–23. http://dx.doi.org/10.1017/s0317167100048241.

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ABSTRACT:Five patients with evidence of focal encephalopathy are reported. In each case, evidence of mycoplasma pneumoniae infection was detected. No patient improved with conventional antibiotic therapy, but in three subjects, rapid and complete recovery did occur contemporaneously with the administration of high dose steroid therapy. It is suggested that focal as well as diffuse cerebral or cerebellar lesions may occur as manifestations of auto-immune disease complicating mycoplasmal infections in young people and that this illness may be designated as acute mycoplasma-associated encephalopa
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Lührmann, Anke, Ursula Deiters, Julia Skokowa, et al. "In Vivo Effects of a Synthetic 2-Kilodalton Macrophage-Activating Lipopeptide of Mycoplasma fermentans after Pulmonary Application." Infection and Immunity 70, no. 7 (2002): 3785–92. http://dx.doi.org/10.1128/iai.70.7.3785-3792.2002.

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ABSTRACT Mycoplasmas can cause interstitial pneumonias inducing critical illness in humans and animals. Mycoplasma infections are characterized by an influx of neutrophils, followed by an accumulation of macrophages and lymphocytes. The present study deals with the question of which mycoplasmal components cause this host reaction. The mycoplasma-derived, macrophage-activating lipopeptide 2S-MALP-2 was used to mimic the sequelae of a mycoplasma infection. To this end, 2S-MALP-2 was intratracheally instilled into the lungs of Lewis rats, and the bronchoalveolar lavage cells were examined at diff
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Cacciotto, Carla, and Alberto Alberti. "Eating the Enemy: Mycoplasma Strategies to Evade Neutrophil Extracellular Traps (NETs) Promoting Bacterial Nucleotides Uptake and Inflammatory Damage." International Journal of Molecular Sciences 23, no. 23 (2022): 15030. http://dx.doi.org/10.3390/ijms232315030.

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Neutrophils are effector cells involved in the innate immune response against infection; they kill infectious agents in the intracellular compartment (phagocytosis) or in the extracellular milieu (degranulation). Moreover, neutrophils release neutrophil extracellular traps (NETs), complex structures composed of a scaffold of decondensed DNA associated with histones and antimicrobial compounds; NETs entrap infectious agents, preventing their spread and promoting their clearance. NET formation is triggered by microbial compounds, but many microorganisms have evolved several strategies for NET ev
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Thacker, Eileen L., Patrick G. Halbur, Richard F. Ross, Roongroje Thanawongnuwech, and Brad J. Thacker. "Mycoplasma hyopneumoniae Potentiation of Porcine Reproductive and Respiratory Syndrome Virus-Induced Pneumonia." Journal of Clinical Microbiology 37, no. 3 (1999): 620–27. http://dx.doi.org/10.1128/jcm.37.3.620-627.1999.

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An experimental model that demonstrates a mycoplasma species acting to potentiate a viral pneumonia was developed. Mycoplasma hyopneumoniae, which produces a chronic, lymphohistiocytic bronchopneumonia in pigs, was found to potentiate the severity and the duration of a virus-induced pneumonia in pigs. Pigs were inoculated with M. hyopneumoniae 21 days prior to, simultaneously with, or 10 days after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV), which induces an acute interstitial pneumonia in pigs. PRRSV-induced clinical respiratory disease and macroscopic and mi
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Abdelrahman, Abdelrahman A., Salama A. S. Shany, Mansy A. A. Dardeer, Kareem E. Hassan, Ahmed Ali, and Magdy F. El-Kady. "Avian Mycoplasma gallisepticum and Mycoplasma synoviae: Advances in diagnosis and control." German Journal of Veterinary Research 1, no. 2 (2021): 46–55. http://dx.doi.org/10.51585/gjvr.2021.2.0019.

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Both of Mycoplasma gallisepticum (MG) and Mycoplasma synoviae (MS) infections are the most common Mycoplasma infection in domestic poultry. The disease is associated with economic losses in poultry. MG and MS are commonly spread within chickens (Gallus gallus domesticus) and turkeys (Meleagris gallopavo domesticus) flocks; however, they are frequently isolated from quails (Coturnix coturnix) and several avian species. Diagnosis of MG or MS infections is confirmed by isolating the organism in a cell-free medium or directly detecting its DNA in infected tissues or swab samples. Serological tests
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Narita, Mitsuo, Yoshihiro Matsuzono, Takehiro Togashi, and Naofumi Kajii. "DNA Diagnosis of Central Nervous System Infection by Mycoplasma pneumoniae." Pediatrics 90, no. 2 (1992): 250–53. http://dx.doi.org/10.1542/peds.90.2.250.

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A nested polymerase chain reaction method for the detection of Mycoplasma pneumoniae was devised and applied to clinical samples. This system could detect 5 to 50 fg of the DNA from M pneumoniae and did not amplify the DNA from Mycoplasma genitalium. With this method, the sequence of this organism was detected successfully in cerebrospinal fluid samples from four of six patients and in serum samples from three of four patients with clinically and serologically confirmed mycoplasmal central nervous system infection. This strongly suggested the direct invasion of this organism into the central n
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Carvalho, Stephani Félix, Gracielle Teles Pádua, Warley Vieira de Freitas Paula, et al. "Feline Vector-Borne Diseases and Their Possible Association with Hematological Abnormalities in Cats from Midwestern Brazil." Microorganisms 12, no. 11 (2024): 2171. http://dx.doi.org/10.3390/microorganisms12112171.

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Among the parasitic and infectious diseases affecting cats, those caused by vector-borne pathogens deserve attention due to their ability to cause nonspecific clinical signs and clinicopathological abnormalities. We studied the presence of Cytauxzoon spp., Ehrlichia spp., and Mycoplasma spp. in blood samples from 135 cats referred to the veterinary teaching hospital of the Federal University of Goiás in midwestern Brazil. We also investigated co-infections with Feline Immunodeficiency Virus (FIV) and Feline Leukemia Virus (FeLV) as well as the correlation between Mycoplasma spp. infection and
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Hoxha, Ina, Iwona Lesiak-Markowicz, Julia Walochnik, Angelika Stary, and Ursula Fürnkranz. "The Prevalence of Genital Mycoplasmas and Coinfection with Trichomonas vaginalis in Female Patients in Vienna, Austria." Microorganisms 11, no. 4 (2023): 933. http://dx.doi.org/10.3390/microorganisms11040933.

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Trichomonas vaginalis causes trichomoniasis, the most recurrent sexually transmitted infection (STI) worldwide. Genital mycoplasmas, not considered STI agents, are frequently isolated from the female genital tract. A symbiosis between Mycoplasma species and T. vaginalis has been described. The aim of this study was to conduct molecular-based analyses of vaginal specimens, thus assessing the prevalence of non-STI Mycoplasma infections. In total, 582 samples from female patients and an additional 20 T. vaginalis isolates were analyzed by PCR using Mycoplasma specific 16S rRNA primers, and the ob
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Vande Voorde, Johan, Federico Gago, Kristof Vrancken, Sandra Liekens, and Jan Balzarini. "Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues." Biochemical Journal 445, no. 1 (2012): 113–23. http://dx.doi.org/10.1042/bj20112225.

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In the present paper we demonstrate that the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and show that the phosphorolytic activity of the mycoplasmas is responsible for this. Since mycoplasmas are (i) an important cause of secondary infections in immunocompromised (e.g. HIV infected) patients and (ii) known to preferentially colonize tumour tissue in cancer patients, catabolic mycoplasma enzymes may compromise efficient chemotherapy of virus infections and cancer. In the genome of M. hyorhinis, a TP (thymidine p
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Madsen, Melissa L., Supraja Puttamreddy, Eileen L. Thacker, Michael D. Carruthers, and F. Chris Minion. "Transcriptome Changes in Mycoplasma hyopneumoniae during Infection." Infection and Immunity 76, no. 2 (2007): 658–63. http://dx.doi.org/10.1128/iai.01291-07.

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ABSTRACT Mycoplasma hyopneumoniae causes swine pneumonia and contributes significantly to the porcine respiratory disease complex. The mechanisms of pathogenesis are difficult to address, since there is a lack of genetic tools, but microarrays are available and can be used to study transcriptional changes that occur during disease as a way to identify important virulence-related genes. Mycoplasmas were collected from bronchial alveolar lavage samples and compared to broth-grown cells using microarrays. Bronchial alveolar lavage was performed on pigs 28 days postinfection, and mycoplasmas were
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Mesquita, João R., Ana C. Oliveira, Frederico Neves, et al. "Hemotropic Mycoplasma and Bartonella Species Diversity in Free-Roaming Canine and Feline from Luanda, Angola." Pathogens 10, no. 6 (2021): 735. http://dx.doi.org/10.3390/pathogens10060735.

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Free-roaming dogs and cats represent potential reservoirs for zoonotic vector-borne pathogens shedding to the human population. Given the health impact of these pathogens, we searched free-roaming dogs and cats included in an animal population control program from Luanda, Angola, for Bartonella and hemotropic mycoplasma infection. We report the detection of Bartonella henselae (2/66; 3%), Candidatus Mycoplasma haemominutum (5/66; 7.5%) and Mycoplasma haemofelis (1/66; 1.5%) in cats. One dog was found positive for Mycoplasma haemocanis (1/20; 5%). This is the first report of Bartonella henselae
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Firmino, Fernanda P., Larissa C. Aquino, Tatiana G. Marçola, Marta V. Bittencourt, Concepta M. McManus, and Giane R. Paludo. "Frequency and hematological alterations of different hemoplasma infections with retrovirusis co-infections in domestic cats from Brazil." Pesquisa Veterinária Brasileira 36, no. 8 (2016): 731–36. http://dx.doi.org/10.1590/s0100-736x2016000800009.

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Abstract: Mycoplasma haemofelis is the agent of feline infectious anemia, although Candidatus M. haemominutum can also be associated. This study evaluated the frequency and hematological alterations caused by hemoplasma infections and co-infections with FeLV, FIV and Toxoplasma gondii in domestic cats from two distinct areas (urban - G1 and periurban - G2) of Brasília, Brazil. One hundred cats were evaluated, 51 from the G1 area and 49 from G2. No cats were positive for T. gondii. Hemoplasma infection was diagnosed in 33% cats from G1 and 32.6% from G2 (p&gt;0.05). In G1 35.3% of the positive
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Nakhanov, A. K., A. A. Terebay, L. G. Marahovskaya, S. K. Kokanov, and B. A. Seydakhmetova. "EVALUATION OF METHODS FOR THE DETECTION OF MYCOPLASMA CONTAMINATION OF CELL CULTURES AND THE EFFECTIVENESS OF ANTIMYCOPLASMA PREPARATIONS." Biosafety and Biotechnology, no. 20 (September 16, 2024): 45–56. https://doi.org/10.58318/2957-5702-2024-20-45-56.

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This article presents the results of a study on the detection of mycoplasma infection in various cell lines and the evaluation of the effectiveness of antimycoplasma drugs. To detect mycoplasmas in cell cultures, DNA fluorochrome (DAPI, Apollo Scientific) staining methods, PlasmoTest™ (Invivogen, France), MycoStrip (Invivogen, France) and EZ-PCR™ (Biological Industries, Israel) kits were used, which are widely recommended for detecting mycoplasmas in cell culture. Based on the obtained research results, it was found that the antimycoplasma drugs MycoZap (Lonza Bioscience), Plasmocin (Invivogen
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Taylor-Robinson, D., and Patricia M. Furr. "Urinary-tract infection by Mycoplasma pulmonis in mice and its wider implications." Journal of Hygiene 96, no. 3 (1986): 439–46. http://dx.doi.org/10.1017/s0022172400066213.

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SUMMARYYoung adult mice were inoculated intravenously with strains JB or Peter C of Mycoplasma pulmonis. A few were inoculated intranasally with strain JB. This strain but not Peter C was isolated for 50 days or more from the urines of more than half of the mice. Those of strains TO, C3H and CBA, but not CFLP, were susceptible. Recovery of mycoplasmas was intermittent and sometimes the numbers isolated varied within individual mice and between mice of a particular strain, ranging from 5 × 101 to &lt;5 × 107 colour-changing units/ml. Fifty serial passes of M. pulmonis, strain JB, in mycoplasmal
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Hoffman, Richard W., M. Page Luttrell, and William R. Davidson. "REPRODUCTIVE PERFORMANCE OF MERRIAM'S WILD TURKEYS WITH SUSPECTED MYCOPLASMA INFECTION." Wildlife Society Bulletin 1995, S1 (1995): 145–51. https://doi.org/10.1002/j.2328-5540.1995.tb00224.x.

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Abstract: Mycoplasma spp. infections may suppress wild turkey populations through subtle changes in reproductive performance. As part of an investigation of Mycoplasma spp. infections in a population of Merriam's wild turkeys (Meleagris gallopavo merriami) in west‐central Colorado, we measured reproductive parameters of 111 (50 adults, 61 subadults) radio‐marked hens during 1992‐93. Serologic testing using the rapid plate agglutination (RPA) assay disclosed seroreactors to three pathogenic mycoplasmas: M. gallisepticum (MG), M. synoviae (MS), and M. meleagridis (MM). However, cultural surveys
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Bui, Nghia Quang, Cuong Thi Kim Mai, Nguyet Kim Nguyen, Thang Nguyen, and Linh My Duong. "Characteristics of asthmatic children with <em>Mycoplasma pneumoniae</em> infection in Vietnam." Sri Lanka Journal of Child Health 53, no. 1 (2024): 15–19. http://dx.doi.org/10.4038/sljch.v53i1.10672.

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Introduction: Mycoplasma pneumoniae is regarded as an involved factor in refractory asthma exacerbations. The link between Mycoplasma pneumoniae infection and asthma is not fully understood, particularly regarding clinical and paraclinical characteristics.Objectives: To determine the frequency of Mycoplasma pneumoniae infection in asthmatic children, identify clinical and paraclinical characteristics along with clinical management in children aged 6 to 15 years at Can Tho Children's Hospital, Vietnam.Method: From March 2019 to April 2021, 124 patients participated in a cross-sectional study th
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Fenelon, Ana Carolina Guimarães, Aline Santana da Hora, Karolinna Lourenço da Silva, et al. "Co-infection of Cytauxzoon felis, Mycoplasma haemofelis, and the feline immunodeficiency virus in a domestic cat in Uberlândia, Minas Gerais, Brazil." Brazilian Journal of Veterinary Research and Animal Science 60 (December 14, 2023): e210131. http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2023.210131.

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Cytauxzoon felis is a hemoparasite capable of infecting domestic and wild cats. Studies suggest that wild cats are the main reservoirs of the protozoan, and transmission occurs through the bite of an infected tick. Hemotropic mycoplasmas are Gram-negative bacteria responsible for severe hemolytic anemia. The feline immunodeficiency virus (FIV) is a retrovirus capable of generating immunosuppression in the host and persistent infection. The present work describes a case of co infection of Cytauxzoon felis, Mycoplasma haemofelis, and feline immunodeficiency virus (FIV) in a cat. A feline from th
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Simecka, Jerry, Xiangle Sun, Nicole Dobbs, Sheetal Bodhankar, and Harlan Jones. "Dendritic cells are the major antigen presenting cells in inflammatory lesions of murine mycoplasma respiratory disease and contribute to disease severity (P3306)." Journal of Immunology 190, no. 1_Supplement (2013): 134.6. http://dx.doi.org/10.4049/jimmunol.190.supp.134.6.

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Abstract Mycoplasmas cause chronic respiratory diseases in animals and humans, and vaccine development has been problematic. T cell responses were shown to confer protection as well as promote immunopathology in murine mycoplasma pneumonia. Because T cells play a critical role, the role of antigen presenting cells (APC) was examined as they likely influence either an increase in disease severity or promote protective immunity. The roles of APC, such as dendritic cells (DC) and macrophages, in mycoplasma disease are currently unknown. In this study, we examined the ability pulmonary APC populat
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Feriyawati, Lita, Dwi Rita Anggraini, and Tetty Aman Nasution. "Co-Infection of Human Papillomavirus with Mycoplasma Hominis/Ureaplasma Urealyticum Among Female Sex Workers in Medan, Indonesia." Open Access Macedonian Journal of Medical Sciences 7, no. 20 (2019): 3425–28. http://dx.doi.org/10.3889/oamjms.2019.438.

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Human papillomavirus (HPV) infection is one of the most prevalent sexually transmitted diseases among women aged &lt; 35 years worldwide. Recent studies have suggested that the vaginal microenvironment influenced by bacterial infection poses for high-risk human papillomavirus (hrHPV) infection and cervical carcinogenesis. Female sex workers (FSWs) are a population susceptible to acquire Human Immunodeficiency Virus (HIV) and sexually transmitted infections (STIs), as well as transmitting the virus to others. The aim of this study is to evaluate the relationship between Mycoplasma/Ureaplasma in
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Yacoub, Elhem, Daniel Kos, and Murray Jelinski. "Virulence Is More than Adhesion and Invasion Ability, an In Vitro Cell Infection Assay of Bovine Mycoplasma spp." Microorganisms 13, no. 3 (2025): 632. https://doi.org/10.3390/microorganisms13030632.

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Mycoplasma bovis is the most common mycoplasma associated with cattle diseases worldwide. However, other seemingly less virulent Mycoplasma spp. such as M. bovigenitalium and M. bovirhinis have also been associated with mycoplasmosis. The study objective was to compare the adhesion and cellular invasion characteristics of these bovine Mycoplasma spp. using Madin–Darby Bovine Kidney (MDBK) epithelial cells. MDBK cells were separately infected with 12 M. bovis strains and one strain each of M. bovigenitalium and M. bovirhinis. Following infection, a gentamicin protection assay was performed and
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Yu, Jie, Shanshan Yu, Liye Zhu, et al. "Is there an association between recurrent spontaneous abortion and mycoplasma infection?" Journal of Infection in Developing Countries 16, no. 08 (2022): 1302–7. http://dx.doi.org/10.3855/jidc.15134.

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Introduction: Recurrent spontaneous abortion (RSA) is an important reproductive health issue with a serious adverse effect on patients and their families worldwide. The present study evaluated the association between mycoplasma infections and RSA in pregnant patients.&#x0D; Methodology: This case-control study included 107 patients with RSA (study group) and 89 normal pregnant women who had planned abortions (control group) between March 2019 and February 2021. Cervical swabs were assessed for the presence of Mycoplasma hominis and Ureaplasma urealyticum by Microtiter Plate Hybridization assay
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Власова, Марина, Marina Vlasova, Стефания Супрун, et al. "INFLUENCE OF THE MASSIVENESS OF INFECTION OF THE GENITAL TRACT WITH UROGENITAL MYCOPLASMAS ON THE COURSE AND OUTCOMES OF PREGNANCY IN WOMEN OF THE AMUR REGION." Bulletin physiology and pathology of respiration 1, no. 70 (2018): 61–67. http://dx.doi.org/10.12737/article_5c12687ab9c208.73028019.

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In order to study the role of urogenital mycoplasmas on the course and outcomes of pregnancy, depending on its quantitative assessment using the real-time PCR, 159 rural women of the Amur region were examined. Infection with Ureaplasma species (spp.) was revealed in 51.2% of cases, among them in clinically significant concentrations (in the form of monoinfection or in combination with other opportunistic microorganisms) it was found in 39.0% of cases. Mycoplasma hominis in clinically significant concentration was determined in 15.1% of pregnant women, among them in 8.8% it was in combination w
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Uusküla, Anneli, and Peter K. Kohl. "Genital mycoplasmas, including Mycoplasma genitalium, as sexually transmitted agents." International Journal of STD & AIDS 13, no. 2 (2002): 79–85. http://dx.doi.org/10.1258/0956462021924695.

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Mycoplasmas are the smallest free-living organisms, widespread in nature. Several mycoplasma species have been isolated from humans. For 6 of them: Mycoplasma hominis, Ureaplasma urealyticum, M. primatum, M. genitalium, M. spermatophilum and M. penetrans, the genital tract is the main site of colonization. This review is concentrated on the role of mycoplasmas as sexually transmitted agents, with the emphasis to M. genitalium infections. M. hominis and U. urealyticum are isolated from the genital tract of healthy men and women with considerable frequency. The biological features (attachment pr
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Bashiri, Fahad A. "Mycoplasma pneumoniae Infection." Global Pediatric Health 2 (January 1, 2015): 2333794X1559276. http://dx.doi.org/10.1177/2333794x15592764.

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Singh, Ameeta E., Annie-Claude Labbé, and Ulrick Auguste. "Mycoplasma genitalium infection." Canadian Medical Association Journal 191, no. 4 (2019): E103. http://dx.doi.org/10.1503/cmaj.180881.

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Yoshimoto, Kiyomi, Masaki Matsubara, Tadanao Kobayashi, and Kenji Nishio. "A Case of Mycoplasma Infection with an Atypical Presentation of Abducens Nerve Palsy, Erythema Multiforme and Polyarthritis without Respiratory Manifestations." Medicina 60, no. 1 (2023): 36. http://dx.doi.org/10.3390/medicina60010036.

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Mycoplasma pneumoniae is a self-propagating microorganism that commonly causes respiratory tract infections. It can also cause a variety of extrapulmonary symptoms with or independently of respiratory symptoms, such as skin lesions, arthralgia, myalgia, hemolysis, cardiac lesions, gastrointestinal symptoms, and central nervous system lesions, which are rare manifestations reported in approximately 0.1% of cases. In this study, we present a unique case of Mycoplasma-related abducens nerve palsy, polyarthritis, and erythema multiforme without respiratory disease. The patient was a 69-year-old wo
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Xu, Xiang, Dongji Zhang, Hong Zhang, et al. "Neutrophil histamine contributes to inflammation in mycoplasma pneumonia." Journal of Experimental Medicine 203, no. 13 (2006): 2907–17. http://dx.doi.org/10.1084/jem.20061232.

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Mycoplasmas cause chronic inflammation and are implicated in asthma. Mast cells defend against mycoplasma infection and worsen allergic inflammation, which is mediated partly by histamine. To address the hypothesis that mycoplasma provokes histamine release, we exposed mice to Mycoplasma pulmonis, comparing responses in wild-type and mast cell–deficient KitW-sh/KitW-sh (W-sh) mice. Low histamine levels in uninfected W-sh mice confirmed the conventional wisdom that mast cells are principal sources of airway and serum histamine. Although mycoplasma did not release histamine acutely in wild-type
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Pageaut, Héloïse, Sonia Lacouture, Mélanie Lehoux, Corinne Marois-Créhan, Mariela Segura, and Marcelo Gottschalk. "Interactions of Mycoplasma hyopneumoniae and/or Mycoplasma hyorhinis with Streptococcus suis Serotype 2 Using In Vitro Co-Infection Models with Swine Cells." Pathogens 12, no. 7 (2023): 866. http://dx.doi.org/10.3390/pathogens12070866.

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Bacterial and/or viral co-infections are very common in swine production and cause severe economic losses. Mycoplasma hyopneumoniae, Mycoplasma hyorhinis and Streptococcus suis are pathogenic bacteria that may be found simultaneously in the respiratory tracts of pigs. In the present study, the interactions of S. suis with epithelial and phagocytic cells in the presence or absence of a pre-infection with M. hyopneumoniae and/or M. hyorhinis were studied. Results showed relatively limited interactions between these pathogens. A previous infection with one or both mycoplasmas did not influence th
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Amitai, D. Ben, I. Zahavi, G. Dinari, and B. Z. Garty. "Transient Protein‐Losing Hypertrophic Gastropathy Associated with Mycoplasma pneumoniae Infection in Childhood." Journal of Pediatric Gastroenterology and Nutrition 14, no. 2 (1992): 237–39. http://dx.doi.org/10.1002/j.1536-4801.1992.tb10532.x.

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SummaryA 3‐year‐old boy with transient protein loss due to hypertrophic gastropathy is described. Serologic evidence of concomitant Mycoplasma pneumoniae infection was present. Although sometimes associated with infections, protein‐losing hypertrophic gastropathy has not been reported previously in association with Mycoplasma pneumoniae infection.
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Ali, Saja, Saad Atiyah, and Aseel Jabber. "Molecular Detection of Ureaplasma Urealyticum in Pregnant Woman Suffering from Urinary Tract Infection." International Journal for Scientific Research 3, no. 1 (2024): 263–79. http://dx.doi.org/10.59992/ijsr.2024.v3n1p11.

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Mycoplasma is a genus of bacteria that lack a cell wall, The present study was designed to identify the Ureaplasma urelyticium which causes the pregnant women suffering uti. The study included 200 samples of 150 pregnant women and 50 controls from the Bint Al-Huda teaching Hospital and Al-Haboubi teaching Hospital in the Thi-Qar provainc. The presence of the GPO gene in urine samples by using the PCR used as an indicator for mycoplasma colonization of urinary tract of pregnant, then the species was detected by DNA sequencing. in this study Regarding the GPO gene most of the cases were carry my
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Glinkina, T. V. "Molecular Genetic Diagnostics and Features of the Species Structure of the Pathogenic Flora in Chlamydia and Mycoplasma Infection of the Respiratory Tract in Children." Health and Ecology Issues, no. 4 (December 28, 2019): 11–16. http://dx.doi.org/10.51523/2708-6011.2019-16-4-2.

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Objective : to determine the features of the infection caused by Сhlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae in children with bronchitis and pneumonia and to improve the methodology of molecular genetic diagnostics of the respiratory infections caused by chlamydia and mycoplasma.Material and methods. 272 children aged 0-17 diagnosed with bronchitis, pneumonia, were examined for the presence of chlamydia-mycoplasma respiratory tract infection by Realtime PCR.Results. The study has revealed a high proportion of chlamydia and mycoplasma associations (23
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Sybilski, Adam J. "Atypical pathogen infection of respiratory system." Medycyna Faktów 14, no. 1 (2021): 78–81. http://dx.doi.org/10.24292/01.mf.0121.10.

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The frequency of respiratory infections, especially atypical pneumonia, is increasing significantly. Most often, atypical pneumonia is caused by Mycoplasma pneumoniae and Chlamydophila pneumoniae. Human is the only reservoir of these atypical bacteria. The infection occurs via droplets or direct contact with a sick person or convalescent. Pneumonia of the etiology of Mycoplasma pneumoniae and Chlamydophila pneumoniae most often affects children without comorbidities and is usually mild, while most patients with Legionella infection require intensive care treatment. Symptoms of mycoplasma infec
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Vidić, Branka, Sara Savić, Živoslav Grgić, Ljiljana Suvajdžić, and Nadežda Prica. "SEROEPIDEMIOLOGICAL INVESTIGATION OF MYCOPLASMA BOVIS IN CALVES." Archives of Veterinary Medicine 7, no. 1 (2015): 3–9. http://dx.doi.org/10.46784/e-avm.v7i1.119.

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Within the multifactorial etiology of respiratory infections in cattle, Mycoplasmae play an important role. Most of the Mycoplasma microorganisms play a minor role in the development of the infections in cattle, contrary to Mycoplasma bovis (M. bovis) that is commonly the primary agent of the disease. Respiratory tract mucosa is the primary colonization site of M. bovis in cattle. Colonization of the upper respiratory tract of calves with M.bovis oft en occurs within the fi rst few weeks of life. Animals with chronic infection and without clinical symptoms occasionally shed M.bovis and they ar
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48

Kuvardina, H. O., F. S. Kharlamova, I. V. Polesko, O. V. Shamsheva, and O. S. Ostapuschenko. "The role of mixed Mycoplasma and Herpesvirus infections in case of skin lesions in children." CHILDREN INFECTIONS 18, no. 3 (2019): 5–10. http://dx.doi.org/10.22627/2072-8107-2019-18-3-5-10.

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Numerous literature data show the role of mycoplasma infection in the development of non-respiratory lesions of various organs and systems, including the skin. Herpesvirus and mycoplasma infections can trigger the development of immune-mediated inflammatory reactions of the skin and mucous membranes — erythema multiforme exudative, Stevens-Johnson syndrome, vesicular pustular dermatosis — Sneddon-Wilkinson syndrome, etc.In order to study the frequency and nature of skin lesions with mycoplasmosis combined with herpesvirus infection, 45 patients aged 3 to 15 years of life were observed. A compr
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Pan, Qiao, Yujuan Zhang, Tong Liu, Qingyuan Xu, Qi Wu, and Jiuqing Xin. "Mycoplasma glycine cleavage system key subunit GcvH is an apoptosis inhibitor targeting host endoplasmic reticulum." PLOS Pathogens 20, no. 5 (2024): e1012266. http://dx.doi.org/10.1371/journal.ppat.1012266.

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Mycoplasmas are minimal but notorious bacteria that infect humans and animals. These genome-reduced organisms have evolved strategies to overcome host apoptotic defense and establish persistent infection. Here, using Mycoplasma bovis as a model, we demonstrate that mycoplasma glycine cleavage system (GCS) H protein (GcvH) targets the endoplasmic reticulum (ER) to hijack host apoptosis facilitating bacterial infection. Mechanically, GcvH interacts with the ER-resident kinase Brsk2 and stabilizes it by blocking its autophagic degradation. Brsk2 subsequently disturbs unfolded protein response (UP
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Jafarizadeh, Amirreza, Seyed Ali Pourbakhsh, Keyvan Tadayon, Mahmud Jamshidian, and Abbas Ashtari. "Mixed infection zones may be important in the epidemiology of contagious agalactia." Journal of Veterinary Research 60, no. 2 (2016): 159–62. http://dx.doi.org/10.1515/jvetres-2016-0023.

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Abstract Introduction: The current study was designed to detect Mycoplasma agalactiae (Ma), Mycoplasma mycoides subsp. capri (Mmc), Mycoplasma capricolum subsp. capricolum (Mcc) and Mycoplasma putrefaciens (Mp) in sheep and goats with clinical signs consistent with contagious agalactia. Material and Methods: A total of 299 samples were collected from 55 mixed herds in Azarbaijan-e-Sharghi province, Iran. Samples were examined using PCR and culture methods. Results: The findings showed that in 40 herds at least one sample was positive by PCR or culture method. Moreover, out of 274 sheep samples
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