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Journal articles on the topic 'Mycotoxin binders'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Widiyanti, Prima Mei, and Romsyah Maryam. "The Use of Mycotoxin Binder to Control Its Contamination in Feed." Indonesian Bulletin of Animal and Veterinary Sciences 26, no. 2 (2017): 091. http://dx.doi.org/10.14334/wartazoa.v26i2.1329.

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<p class="awabstrak2">The climate in Indonesia as a tropical country is very condusive for the growth of mycotoxins producing fungi. Mycotoxins have properties as carcinogenic, mutagenic, teratogenic, estrogenic, neurotoxic, and immunotoxic. Mycotoxins reduce performance, appetite, weight, and immunity. They also cause reproductive disorders and generate the residues in animal products that affect human health. These can be prevented by controlling mycotoxins contamination in agricultural products that used for feed ingredients through good management practices (during planting, harvesti

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Hoffmans, Yvette, Sara Schaarschmidt, Carsten Fauhl-Hassek, and H. J. van der Fels-Klerx. "Factors during Production of Cereal-Derived Feed That Influence Mycotoxin Contents." Toxins 14, no. 5 (2022): 301. http://dx.doi.org/10.3390/toxins14050301.

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Mycotoxins are naturally present in cereal-based feed materials; however, due to adverse effects on animal health, their presence in derived animal feed should be minimized. A systematic literature search was conducted to obtain an overview of all factors from harvest onwards influencing the presence and concentration of mycotoxins in cereal-based feeds. The feed production processes covered included the harvest time, post-harvest practices (drying, cleaning, storage), and processing (milling, mixing with mycotoxin binders, extrusion cooking, ensiling). Delayed harvest supports the production

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Hoffmans, Yvette, Sara Schaarschmidt, Carsten Fauhl-Hassek, and H. J. van der Fels-Klerx. "Factors during Production of Cereal-Derived Feed That Influence Mycotoxin Contents." Toxins 14, no. 5 (2022): 301. http://dx.doi.org/10.3390/toxins14050301.

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Mycotoxins are naturally present in cereal-based feed materials; however, due to adverse effects on animal health, their presence in derived animal feed should be minimized. A systematic literature search was conducted to obtain an overview of all factors from harvest onwards influencing the presence and concentration of mycotoxins in cereal-based feeds. The feed production processes covered included the harvest time, post-harvest practices (drying, cleaning, storage), and processing (milling, mixing with mycotoxin binders, extrusion cooking, ensiling). Delayed harvest supports the production

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Zhao, Ling, Yue Feng, Jing-Tao Wei, et al. "Mitigation Effects of Bentonite and Yeast Cell Wall Binders on AFB1, DON, and OTA Induced Changes in Laying Hen Performance, Egg Quality, and Health." Toxins 13, no. 2 (2021): 156. http://dx.doi.org/10.3390/toxins13020156.

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The objective of this study was to evaluate the efficacy of mycotoxin binders in reducing the adverse effects of co-occurring dietary aflatoxin B1 (AFB1), deoxynivalenol (DON) and ochratoxin A (OTA) on laying hens. Three hundred and sixty 26-week-old Roman laying hens were randomly allocated into four experimental groups with 10 replicates of nine birds each. The four groups received either a basal diet (BD; Control), a BD supplemented with 0.15 mg/kg AFB1 + 1.5 mg/kg DON + 0.12 mg/kg OTA (Toxins), a BD + Toxins with Toxo-HP binder (Toxins + HP), or a BD + Toxins with TOXO XL binder (Toxins +

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Prastiya, Ragil Angga, Abdul Samik, and Amung Logam Saputro. "Mycotoxin Binders Effect on Ovaries of Pregnant Mice Exposed to Zearalenone." Jurnal Sain Veteriner 37, no. 1 (2019): 127. http://dx.doi.org/10.22146/jsv.48522.

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Mycotoxin, a secondary metabolite produced by mushroom, has proven to cause various cytotoxic effects to animals. Zearalenone is one type of mycotoxin which is produced by Fusarium graminearum mushroom and has a cytotoxic effect to the reproduction system and cattle productivity by inducing apoptosis in the animal's ovaries, uterus, and placenta. This research tested the potentials of mycotoxin binders in eliminating the effect of zearalenone which can be seen from the expression of caspase 3, the content of malondialdehyde (MDA), and the quantity of corpus luteum in the ovaries of pregnant mi

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Debevere, Sandra, Dian Schatzmayr, Nicole Reisinger, et al. "Evaluation of the Efficacy of Mycotoxin Modifiers and Mycotoxin Binders by Using an In Vitro Rumen Model as a First Screening Tool." Toxins 12, no. 6 (2020): 405. http://dx.doi.org/10.3390/toxins12060405.

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Ruminal microbiota of cattle are not able to detoxify all mycotoxins. In addition, detoxification can be hampered by adverse ruminal conditions (e.g., low ruminal pH). Hence, in the cattle husbandry, mycotoxin binders and modifiers could be used to prevent animal exposure to mycotoxins. In this study, an in vitro rumen model, including feed matrix, was established as first screening tool to test the efficacy of five products claiming to detoxify mycotoxins. The detoxifiers had different modes of action: (a) binding (three products); (b) enzymatic detoxification of zearalenone (ZEN; one product

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Kolosova, A., and J. Stroka. "Substances for reduction of the contamination of feed by mycotoxins: a review." World Mycotoxin Journal 4, no. 3 (2011): 225–56. http://dx.doi.org/10.3920/wmj2011.1288.

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The global occurrence of mycotoxins is considered to be a major risk factor for human and animal health. Contamination of different agricultural commodities with mycotoxins still occurs despite the most strenuous prevention efforts. As a result, mycotoxin contaminated feed can cause serious disorders and diseases in farm animals. A number of approaches, such as physical and chemical detoxification procedures, have been used to counteract mycotoxins. However, only a few of them have practical application. A recent and promising approach to protect animals against the harmful effects of mycotoxi

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Albarki, Hajrian Rizqi, Irwan Susanto, Mohammad Miftakhus Sholikin, and Anuraga Jayanegara. "Efficacy of Mycotoxin Binder on Broiler Performance, Organ Weight, Wishbone Weight, and Gut Length: A Meta-Analysis." Veterinary Integrative Sciences 22, no. 2 (2024): 363–77. http://dx.doi.org/10.12982/vis.2024.026.

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Mycotoxin-contaminated feed is one of the main causes of contamination that may increase broiler mortality and impair their production. A total of 161 in vivo data acquired from 31 published articles were used as a database for determining the effectiveness of mycotoxin binders on performance and health of broiler. The Hedges’ d value was employed as a measure of effect size (ES) in the present meta-analysis. Increasing mycotoxin binder in feed enhanced body weight (ES=0.784; P<0.001), decreased feed conversion ratio (ES=-0.87; P<0.001), and decreased mortality (ES=-3.98; P<0.001). In

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Stoev, Stoycho D. "Biocontrol Agents and Natural Feed Supplements as a Safe and Cost-Effective Way for Preventing Health Ailments Provoked by Mycotoxins." Foods 14, no. 11 (2025): 1960. https://doi.org/10.3390/foods14111960.

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The relationships between mycotoxins content in food commodities or feedstuffs and the foodborne diseases is well known. So far, the available data mainly include chemical methods of mycotoxins decontamination for agricultural commodities or raw materials, including mycotoxin binders. Therefore, the possible use of some natural and cost-effective supplements such as herbs, fungi, microorganisms, or plants with powerful and safe protection against mycotoxin-induced health ailments is the main subject of this review paper. Various antagonistic microorganisms or yeast with fungicidal properties,

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Gott, Paige N., and Dian Schatzmayr. "PSVI-8 Detoxification of zearalenone and deoxynivalenol by Biofix® Plus PRO in a molasses-based liquid feed supplement in an in vitro rumen batch culture system." Journal of Animal Science 97, Supplement_3 (2019): 197–98. http://dx.doi.org/10.1093/jas/skz258.407.

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Abstract Supplementation of animal feeds with mycotoxin binders is routinely used to mitigate mycotoxin challenges. Adsorption efficiency of a binder is dependent on the structure and chemical properties of the mycotoxin, binder, and the complex gastrointestinal environment. Limited adsorption of non-polar mycotoxins has driven innovation of mitigation strategies including biotransformation or detoxification of mycotoxins by microorganisms and enzymatic activity. The current objective was to measure the efficacy of Biofix® Plus PRO (BPL) within a molasses-based liquid feed supplement to detoxi

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Kumari, Priyanka, P. K. Singh, Dharmendra Kumar, et al. "Comparative efficacy of mycotoxin binder and herbal mixture on growth performance, nutrients retention, haemato-biochemicals and immune competence of broiler chicken." Animal Nutrition and Feed Technology 25, no. 1 (2025): 109–21. https://doi.org/10.5958/0974-181x.2025.00010.x.

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AbstractAn experiment was conducted to evaluate the efficacy of synthetic mycotoxin binder mycotoxin binder and herbal mixture in broiler chicken. A total of 200 day-old chicks were procured and randomly allotted using completely randomised design (CRD) to 4 treatment groups (T1-T4) with 5 replicates each having 10 chicks per replicates. All the experimental birds were reared for 35 days following standard and uniform manage mental conditions. Four iso-nitrogenous and iso-caloric experimental diets for prestarter (0-7 days), starter (8-21 days) and finisher (22-35 days) were formulated followi

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KABAK, BULENT, and ALAN D. W. DOBSON. "Biological Strategies To Counteract the Effects of Mycotoxins." Journal of Food Protection 72, no. 9 (2009): 2006–16. http://dx.doi.org/10.4315/0362-028x-72.9.2006.

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Mycotoxins are fungal secondary metabolites that if ingested can cause a variety of adverse effects on both humans and animals, ranging from allergic responses to death. Therefore, exposure to mycotoxins should be minimized. A variety of physical, chemical, and biological methods have been developed for decontamination and/or detoxification of mycotoxins from contaminated foods and feeds. This overview details the latest developments in the biological control of both fungal infection and mycotoxin formation and describes the detoxification of many of the most important mycotoxins by microorgan

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Srinual, Orranee, Tossapol Moonmanee, Chompunut Lumsangkul, et al. "Can Red Yeast (Sporidiobolus pararoseus) Be Used as a Novel Feed Additive for Mycotoxin Binders in Broiler Chickens?" Toxins 14, no. 10 (2022): 678. http://dx.doi.org/10.3390/toxins14100678.

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Mycotoxin-contaminated feeds may negatively affect broiler chickens' health; hence, a sustainable approach to achieve mycotoxin elimination is necessary. This study aimed to evaluate the efficacy of red yeast (Sporidiobolus pararoseus; RY) as a novel mycotoxin binder in broilers. A total of 1440 one-week-old male broiler chicks were randomly assigned to 12 treatments in a 3 × 4 factorial design. The dietary treatments included three levels of mycotoxin-contaminated diets (0 µg kg−1 (0% of mycotoxin; MT), 50 µg kg−1 (50% MT), and 100 µg kg−1 (100% MT)) and four levels of mycotoxin binders (0.0

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Horky, Pavel, Sylvie Skalickova, Daria Baholet, and Jiri Skladanka. "Nanoparticles as a Solution for Eliminating the Risk of Mycotoxins." Nanomaterials 8, no. 9 (2018): 727. http://dx.doi.org/10.3390/nano8090727.

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Mycotoxins are toxic secondary metabolites produced by certain filamentous fungi. The occurrence of mycotoxins in food and feed causes negative health impacts on both humans and animals. Clay binders, yeast cell walls, or antioxidant additives are the most widely used products for mycotoxin elimination to reduce their impact. Although conventional methods are constantly improving, current research trends are looking for innovative solutions. Nanotechnology approaches seem to be a promising, effective, and low-cost way to minimize the health effects of mycotoxins. This review aims to shed light

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Okasha, Hamada, Bochen Song, and Zhigang Song. "Hidden Hazards Revealed: Mycotoxins and Their Masked Forms in Poultry." Toxins 16, no. 3 (2024): 137. http://dx.doi.org/10.3390/toxins16030137.

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The presence of mycotoxins and their masked forms in chicken feed poses a significant threat to both productivity and health. This review examines the multifaceted impacts of mycotoxins on various aspects of chicken well-being, encompassing feed efficiency, growth, immunity, antioxidants, blood biochemistry, and internal organs. Mycotoxins, toxic substances produced by fungi, can exert detrimental effects even at low levels of contamination. The hidden or masked forms of mycotoxins further complicate the situation, as they are not easily detected by conventional methods but can be converted in

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Amer, Mohamed Mahrous, and Aziza Mahrous Amer. "Interactions between mycotoxins and gut microbiota in chickens - review." EUREKA: Life Sciences, no. 1 (April 24, 2025): 41–47. https://doi.org/10.21303/2504-5695.2025.003782.

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This article briefly highlights the complex relationships between the chicken gastrointestinal tract (GIT) microbial communities and mycotoxins. The gut microbiota, the diverse community of microorganisms that reside in the GIT, plays a crucial role in the overall health and well-being of chickens. The mycotoxins can alter gut microbiota composition, leading to potential health issues in poultry. The interactions between mycotoxins and gut microbiota in chickens are complex and significant for poultry health. Mycotoxins are toxic compounds produced by fungi that contaminate feed and can advers

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Ait Issad, Nassima, Nora Mimoune, Djamal Khelef, et al. "Učinci vezivanja toksina i organskog sredstva za zakiseljavanje na zootehničke karakteristike tovnih pilića." Veterinarska stanica 53, no. 6 (2022): 689–98. http://dx.doi.org/10.46419/vs.53.6.4.

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Combatting mycotoxins and their harmful effects on performance at broiler farms is based on using neutralizing products such as binders that inhibit their intestinal absorption and bind with these molecules to neutralise. This study focuses on the dietary supplementation of a mycotoxin binder-organic acidifier combination over an entire broiler rearing cycle. 1280 1-day-old chicks of equal weight of the cobb500 strain were divided into two groups (n=640): the control group (C) was fed with standard staple food suitable for each phase of breeding, while the experimental group received the same

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Faisal, Zelma, Eszter Fliszár-Nyúl, Luca Dellafiora, et al. "Cyclodextrins Can Entrap Zearalenone-14-Glucoside: Interaction of the Masked Mycotoxin with Cyclodextrins and Cyclodextrin Bead Polymer." Biomolecules 9, no. 8 (2019): 354. http://dx.doi.org/10.3390/biom9080354.

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Zearalenone (ZEN) is a Fusarium-derived xenoestrogenic mycotoxin. In plants, zearalenone-14-O-β-d-glucoside (Z14G) is the major conjugated metabolite of ZEN, and is a masked mycotoxin. Masked mycotoxins are plant-modified derivatives, which are not routinely screened in food and feed samples. Cyclodextrins (CDs) are cyclic oligosaccharides built up from D-glucopyranose units. CDs can form stable host–guest type complexes with lipophilic molecules (e.g., with some mycotoxins). In this study, the interaction of Z14G with native and chemically modified β- and γ-CDs was examined employing fluoresc

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Poór, Miklós, Beáta Lemli, Péter Vilmányi, et al. "Probing Serum Albumins and Cyclodextrins as Binders of the Mycotoxin Metabolites Alternariol-3-Glucoside, Alternariol-9-Monomethylether-3-Glucoside, and Zearalenone-14-Glucuronide." Metabolites 13, no. 3 (2023): 446. http://dx.doi.org/10.3390/metabo13030446.

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Mycotoxins are toxic metabolites of molds. Chronic exposure to alternariol, zearalenone, and their metabolites may cause the development of endocrine-disrupting and carcinogenic effects. Alternariol-3-glucoside (AG) and alternariol-9-monomethylether-3-glucoside (AMG) are masked derivatives of alternariol. Furthermore, in mammals, zearalenone-14-glucuronide (Z14Glr) is one of the most dominant metabolites of zearalenone. In this study, we examined serum albumins and cyclodextrins (CDs) as potential binders of AG, AMG, and Z14Glr. The most important results/conclusions were as follows: AG and AM

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Sana, Saba, Ayesha Khan, and Yasir Zahoor. "Mycotoxin Binding Potential of Yeast Species." Lahore Garrison University Journal of Life Sciences 4, no. 03 (2020): 240–45. http://dx.doi.org/10.54692/lgujls.2020.0403115.

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ABSTRACT:Fungal species are capable of producing toxic secondary metabolites commonly known as mycotoxins. One of the important group of mycotoxins are aflatoxins. There are mainly four kinds of aflatoxins AFB1, AFB2, AFG1 and AFG2. Other important mycotoxins are ochratoxin, trichothescens, fumonisins and ergot alkaloids. These aflatoxins are produced by the Aspergillus flavus, A. parasiticus and various other fungal species. These mycotoxins can infect our feed items before or after harvesting the crops. These can contaminate all kinds of food such as grains, spices, nuts and dry fruits. Thes

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Nikolov, Nikolay, Tsvetelina Petkova, Rumen Binev, and Aneliya Milanova. "Low Doses of Deoxynivalenol and Zearalenone Alone or in Combination with a Mycotoxin Binder Affect ABCB1 mRNA and ABCC2 mRNA Expression in the Intestines of Pigs." Toxics 12, no. 4 (2024): 297. http://dx.doi.org/10.3390/toxics12040297.

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Mycotoxin binders, in combination with enzymes degrading some mycotoxins, contribute to feed detoxification. Their use reduces economic losses and the negative impacts of mycotoxins on animal health and productivity in farm animals. The aim of this study was to evaluate the efficacy of a mycotoxin detoxifier on the expression of the ATP-binding cassette efflux transporters ABCB1 mRNA and ABCC2 mRNA, which transport xenobiotics and thus have a barrier function, in the tissues of pigs exposed to low doses of deoxynivalenol (DON, 1 mg/kg feed) and zearalenone (ZEN, 0.4 mg/kg feed) for 37 days. Th

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Yiannikouris, Alexandros, Juha Apajalahti, Osmo Siikanen, Gerald Patrick Dillon, and Colm Anthony Moran. "Saccharomyces cerevisiae Cell Wall-Based Adsorbent Reduces Aflatoxin B1 Absorption in Rats." Toxins 13, no. 3 (2021): 209. http://dx.doi.org/10.3390/toxins13030209.

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Mycotoxins are naturally occurring toxins that can affect livestock health and performance upon consumption of contaminated feedstuffs. To mitigate the negative effects of mycotoxins, sequestering agents, adsorbents, or binders can be included to feed to interact with toxins, aiding their passage through the gastrointestinal tract (GI) and reducing their bioavailability. The parietal cell wall components of Saccharomyces cerevisiae have been found to interact in vitro with mycotoxins, such as, but not limited to, aflatoxin B1 (AFB1), and to improve animal performance when added to contaminated

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Tornike, LASHKARASHVILI, and CHKUASELI Amrosi. "Using new adsorbent Georgian bentonite clay "Askangel" in trout feed." World Journal of Advanced Research and Reviews 24, no. 2 (2024): 2710–16. https://doi.org/10.5281/zenodo.15142899.

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The purpose of this research was to study the effectiveness of bentonite clay of aluminosilicate origin (Askangel) from Georgia as a natural adsorbent of mycotoxins in aquaculture, specifically in trout feeding. The study was conducted on rainbow trout divided into three test groups, each receiving different percentages of Askangel (0.1%, 0.15%,0.2%) in their feed. A synthetic adsorbent was added at 0.1% to the control group’s feed. At the end of the experiment, the weight gain for fish was as follows: 205±0,62 g in the IV test group and 203±0,72 g in the III test group, 18

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Tornike, LASHKARASHVILI, and CHKUASELI Amrosi. "Using new adsorbent Georgian bentonite clay "Askangel" in trout feed." World Journal of Advanced Research and Reviews 24, no. 2 (2024): 2710–16. https://doi.org/10.5281/zenodo.15143089.

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The purpose of this research was to study the effectiveness of bentonite clay of aluminosilicate origin (Askangel) from Georgia as a natural adsorbent of mycotoxins in aquaculture, specifically in trout feeding. The study was conducted on rainbow trout divided into three test groups, each receiving different percentages of Askangel (0.1%, 0.15%,0.2%) in their feed. A synthetic adsorbent was added at 0.1% to the control group’s feed. At the end of the experiment, the weight gain for fish was as follows: 205±0,62 g in the IV test group and 203±0,72 g in the III test group, 18

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Lopicic, Zorica, Aleksandra Bocarov-Stancic, Mirjana Stojanovic, Jelena Milojkovic, Vladimir Pantic, and Milan Adamovic. "In vitro evaluation of the efficacy of peach stones as mycotoxin binders." Zbornik Matice srpske za prirodne nauke, no. 124 (2013): 287–96. http://dx.doi.org/10.2298/zmspn1324287l.

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The paper describes in vitro model for the evaluation of ability of peach shell (unmodified and modified), prepared at the Institute for Technology of Nuclear and Other Mineral Raw Materials, Belgrade, to adsorb different mycotoxins. Peach stones were obtained from ?Vino Zupa? Company from Aleksandrovac, where they have been disposed of as by-products from their Juice Factory. After proper preparation, two sorts of peach shell particles were used: one as unmodified peach shell particles (PS) and another one obtained by acid modification, denoted as MPS. Adsorption of six mycotoxins: aflatoxin

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Ibrahim, Ibrahim, Muhammad Natsir, Osfar Sjofjan, et al. "Optimization growth performance and intestinal characteristics of broiler through the use of zeolite and bioherbal-based mycotoxin binders as feed additives." Journal of Advanced Veterinary and Animal Research 12, no. 1 (2025): 149. https://doi.org/10.5455/javar.2025.l882.

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Objective: This research was designed to explore the potential of mycotoxin binders derived from zeolite and bioherbal formulations as natural feed additives to enhance growth performance and intestinal characteristics in broilers. Materials and Methods: The study utilized 320 Lohmann MB 202 broilers, sourced from PT. Japfa Comfeed Indonesia, commencing from day 1 and extending over a period of 35 days. The methodological framework employed a completely randomized design, incorporating two factors. The primary factor analyzed was the type of feed additive, designated as Zeolite (A1) and Bioher

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Ochieng, Phillis E., Marie-Louise Scippo, David C. Kemboi, et al. "Mycotoxins in Poultry Feed and Feed Ingredients from Sub-Saharan Africa and Their Impact on the Production of Broiler and Layer Chickens: A Review." Toxins 13, no. 9 (2021): 633. http://dx.doi.org/10.3390/toxins13090633.

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The poultry industry in sub-Saharan Africa (SSA) is faced with feed insecurity, associated with high cost of feeds, and feed safety, associated with locally produced feeds often contaminated with mycotoxins. Mycotoxins, including aflatoxins (AFs), fumonisins (FBs), trichothecenes, and zearalenone (ZEN), are common contaminants of poultry feeds and feed ingredients from SSA. These mycotoxins cause deleterious effects on the health and productivity of chickens and can also be present in poultry food products, thereby posing a health hazard to human consumers of these products. This review summar

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Lemli, Beáta, Péter Vilmányi, Eszter Fliszár-Nyúl, et al. "Testing Serum Albumins and Cyclodextrins as Potential Binders of the Mycotoxin Metabolites Alternariol-3-Sulfate, Alternariol-9-Monomethylether and Alternariol-9-Monomethylether-3-Sulfate." International Journal of Molecular Sciences 23, no. 22 (2022): 14353. http://dx.doi.org/10.3390/ijms232214353.

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Alternaria mycotoxins, including alternariol (AOH), alternariol-9-monomethylether (AME), and their masked/modified derivatives (e.g., sulfates or glycosides), are common food contaminants. Their acute toxicity is relatively low, while chronic exposure can lead to the development of adverse health effects. Masked/modified metabolites can probably release the more toxic parent mycotoxin due to their enzymatic hydrolysis in the intestines. Previously, we demonstrated the complex formation of AOH with serum albumins and cyclodextrins; these interactions were successfully applied for the extraction

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Fliszár-Nyúl, Lemli, Kunsági-Máté, Szente, and Poór. "Interactions of Mycotoxin Alternariol with Cyclodextrins and its Removal from Aqueous Solution by Beta-Cyclodextrin Bead Polymer." Biomolecules 9, no. 9 (2019): 428. http://dx.doi.org/10.3390/biom9090428.

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Alternariol is an Alternaria mycotoxin that appears in fruits, tomatoes, oilseeds, and corresponding products. Chronic exposure to it can induce carcinogenic and xenoestrogenic effects. Cyclodextrins (CDs) are ring-shaped molecules built up by glucose units, which form host–guest type complexes with some mycotoxins. Furthermore, insoluble CD polymers seem suitable for the extraction/removal of mycotoxins from aqueous solutions. In this study, the interactions of alternariol with β- and γ-CDs were tested by employing fluorescence spectroscopic and modeling studies. Moreover, the removal of alte

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Ortiz-Martinez, Raul, Claudia Abril Miranda-Castañeda, Arturo Valdivia-Flores, et al. "Use of mycotoxin binders in dairy farms: Preliminary results." Toxicology Letters 229 (September 2014): S225. http://dx.doi.org/10.1016/j.toxlet.2014.06.754.

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Safitri, Erma, Hery Purnobasuki, Tita Damayanti Lestari, et al. "Implementation of mycotoxin binders to enhance immune response and large intestine histopathology against Newcastle disease in vaccinated broiler chickens fed naturally contaminated diet with mixed mycotoxins." F1000Research 13 (December 13, 2024): 1518. https://doi.org/10.12688/f1000research.158103.1.

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Background In broiler farming, vaccination against Newcastle disease (ND) is essential. Nonetheless, during the post-vaccination phase, production may be negatively impacted by mycotoxin contamination in feed. This study aimed to evaluate the effect of toxin binders on antibody titer and large intestine histopathology after ND vaccination in broiler with aflatoxin B1 (AFB1) and ochratoxin A (OTA) toxication. Methods A total of 20 broilers were randomly assigned into 4 groups with 5 replications i.e. (C-) broiler groups with basal feed, (C+) broiler groups with AFB1 and OTA feed contamination,

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Safitri, Erma, Hery Purnobasuki, Tita Damayanti Lestari, et al. "Mycotoxin binder for immune and intestinal histopathology ameliorations against Newcastle disease in vaccinated broilers." F1000Research 13 (January 27, 2025): 1518. https://doi.org/10.12688/f1000research.158103.2.

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Background In broiler farming, vaccination against Newcastle disease (ND) is essential. Nonetheless, during the post-vaccination phase, production may be negatively impacted by mycotoxin contamination in feed. This study aimed to evaluate the effect of mycotoxin binders on immune and intestinal histopathology ameliorations against newcastle disease in vaccinated broilers with aflatoxin B1 (AFB1) and ochratoxin A (OTA) toxication. Methods A total of 20 broilers were randomly assigned into 4 groups with 5 replications i.e. (C-) broiler groups with basal feed, (C+) broiler groups with AFB1 and OT

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Loibl, Peter, Wilhelm Windisch, and Wolfgang Preißinger. "Examination of high-resolution feed intake data of growing-finishing pigs confronted with high deoxynivalenol contents present in their feed." Czech Journal of Animal Science 65, No. 11 (2020): 411–23. http://dx.doi.org/10.17221/189/2020-cjas.

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Modern single space feeding systems for fattening pigs allow the detailed assessment of an individual animal’s feeding behaviour. In an experiment involving 96 fattening pigs, the influence of deoxynivalenol (DON) contaminated feed (&gt; 4 500 µg/kg DON) on the zootechnical performance and feeding behaviour was compared with a feed with low DON concentration (&lt; 900 µg/kg DON), this served as the control group. Additionally, in separate treatments, two commercial mycotoxin binders were added to the DON-contaminated feeds to assess if an expected DON effect could be attenuated. The hi

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Kolawole, Meneely, Greer, et al. "Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims." Toxins 11, no. 11 (2019): 659. http://dx.doi.org/10.3390/toxins11110659.

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Contamination of animal feed with multiple mycotoxins is an ongoing and growing issue, as over 60% of cereal crops worldwide have been shown to be contaminated with mycotoxins. The present study was carried out to assess the efficacy of commercial feed additives sold with multi-mycotoxin binding claims. Ten feed additives were obtained and categorised into three groups based on their main composition. Their capacity to simultaneously adsorb deoxynivalenol (DON), zearalenone (ZEN), fumonisin B1 (FB1), ochratoxin A (OTA), aflatoxin B1 (AFB1) and T-2 toxin was assessed and compared using an in vi

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Samik, Abdul, and Erma Safitri. "Mycotoxin binders potential on histological of ovary mice exposed by zearalenone." Veterinary World 10, no. 3 (2017): 353–57. http://dx.doi.org/10.14202/vetworld.2017.353-357.

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Mil, Thomas De, Mathias Devreese, Sarah De Saeger, Mia Eeckhout, Patrick De Backer, and Siska Croubels. "Influence of Mycotoxin Binders on the Oral Bioavailability of Doxycycline in Pigs." Journal of Agricultural and Food Chemistry 64, no. 10 (2016): 2120–26. http://dx.doi.org/10.1021/acs.jafc.5b06084.

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A Ali, Abdel Moneim. "Ameliorative Effects of Cholestyramine and Oxihumate on Aflatoxicosis in Broiler Chickens." Pakistan Veterinary Journal 41, no. 01 (2021): 51–56. http://dx.doi.org/10.29261/pakvetj/2020.093.

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Aflatoxin B1 (AFB1) is widely available mycotoxin that is secreted by certain types of Aspergilli. In this research the ameliorative efficacy of two mycotoxin binders in broilers was evaluated; cholestyramine which was used for the first time in the poultry and oxihumate. A total of 64 one-day-old chicks were divided into four equal groups: birds of group A, B & C were fed on AFB1 contaminated diet at a rate of 2 ppm for 36 days either alone, with cholestyramine at a dose rate of 340µg/kg ration or with oxihumate at a dose rate of 3.5g/kg ration. Group D was kept as control with basal diet

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Bruinenberg, Paul Gerard, and Mathieu Castex. "Evaluation of a Yeast Hydrolysate from a Novel Strain of Saccharomyces cerevisiae for Mycotoxin Mitigation using In Vitro and In Vivo Models." Toxins 14, no. 1 (2021): 7. http://dx.doi.org/10.3390/toxins14010007.

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Mycotoxicoses in animals are caused by exposure to mycotoxin-contaminated feeds. Disease risk is managed using dietary adsorbing agents which reduce oral bioavailability. The objective of this work was to evaluate the efficacy of three selected yeast products as mycotoxin binders using in vitro and in vivo models. Their capacity to adsorb deoxynivalenol (DON), zearalenone (ZEA), and ochratoxin A (OTA) was evaluated using an in vitro model designed to simulate the pH conditions during gastric passage in a monogastric animal. Results showed that only one product, an enzymatic yeast hydrolysate (

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Jacela, J. Y., Joel M. DeRouchey, Michael D. Tokach, et al. "Feed additives for swine: Fact sheets – flavors and mold inhibitors, mycotoxin binders, and antioxidants." Kansas Agricultural Experiment Station Research Reports, no. 10 (January 1, 2010): 27–32. http://dx.doi.org/10.4148/2378-5977.7069.

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Pappas, A. C., E. Tsiplakou, D. I. Tsitsigiannis, et al. "The role of bentonite binders in single or concomitant mycotoxin contamination of chicken diets." British Poultry Science 57, no. 4 (2016): 551–58. http://dx.doi.org/10.1080/00071668.2016.1187712.

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Jacela, Jay, Joel DeRouchey, Mike Tokach, et al. "Feed additives for swine: Fact sheets – flavors and mold inhibitors, mycotoxin binders, and antioxidants." Journal of Swine Health and Production 18, no. 1 (2010): 27–32. http://dx.doi.org/10.54846/jshap/624c.

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López-Ruiz, Rosalía, Jesús Marin-Saez, Sara C. Cunha, et al. "Investigating the Impact of Dietary Fibers on Mycotoxin Bioaccessibility during In Vitro Biscuit Digestion and Metabolites Identification." Foods 12, no. 17 (2023): 3175. http://dx.doi.org/10.3390/foods12173175.

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Mycotoxins contamination is a real concern worldwide due to their high prevalence in foods and high toxicity; therefore, strategies that reduce their gastrointestinal bioaccessibility and absorption are of major relevance. The use of dietary fibers as binders of four mycotoxins (zearalenone (ZEA), deoxynivalenol (DON), HT-2, and T-2 toxins) to reduce their bioaccessibility was investigated by in vitro digestion of biscuits enriched with fibers. K-carrageenan is a promising fiber to reduce the bioaccessibility of ZEA, obtaining values lower than 20%, while with pectin a higher reduction of DON,

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Swathi, A., JS Sanganal, NB Shridhar, R. Rashmi, G. Prem Kumar, and K. Suhasini. "Effect of Herbal Mycotoxin Binders in Amelioration of Induced Mycotoxicosis in White Leghorn Laying Hens." Science, Technology and Arts Research Journal 3, no. 3 (2014): 63. http://dx.doi.org/10.4314/star.v3i3.11.

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Mutua, Florence, Johanna Lindahl, and Delia Grace. "Availability and use of mycotoxin binders in selected urban and Peri-urban areas of Kenya." Food Security 11, no. 2 (2019): 359–69. http://dx.doi.org/10.1007/s12571-019-00911-4.

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Nazarizadeh, Hasan, and Javad Pourreza. "Evaluation of three mycotoxin binders to prevent the adverse effects of aflatoxin B1 in growing broilers." Journal of Applied Animal Research 47, no. 1 (2019): 135–39. http://dx.doi.org/10.1080/09712119.2019.1584106.

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Kolosova, A., and J. Stroka. "Evaluation of the effect of mycotoxin binders in animal feed on the analytical performance of standardised methods for the determination of mycotoxins in feed." Food Additives & Contaminants: Part A 29, no. 12 (2012): 1959–71. http://dx.doi.org/10.1080/19440049.2012.720035.

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Lao, Emanuel Joel. "SCRUTINIZING THE OPPORTUNITIES, CHALLENGES AND SUSTAINABILITY OF BREWERS’ SPENT GRAIN AS A FEED SOURCE FOR DAIRY CATTLE." Big Data In Agriculture 3, no. 2 (2021): 56–64. http://dx.doi.org/10.26480/bda.02.2021.56.64.

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The current contribution of all agro-industrial by-products is merely 5% of the total livestock feed consumption. The brewers’ spent grain (BSG), being a chief by-product from barley beer brewing has been acknowledged as a high-quality source of animal feed because of its richness in nutritional composition, being generated in bulk, low cost and being environmentally friendly. Inclusion of 25 – 30 % (DM basis) of BSG in dairy cattle feed rations can improve palatability, digestibility and dry matter intake (DMI) which in turn influence the dairy performances such as milk yield, milk compositio

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Yilmaz, D. A. "The content of aflatoxin M1 in the milk of cows from Turkish farms: the effect on milk quality and the effectiveness of mycotoxin binding by a claybased adsorbent." International Journal of Veterinary Medicine, no. 1 (April 2, 2024): 133–41. http://dx.doi.org/10.52419/issn2072-2419.2024.1.133.

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The aim of this study was to evaluate the concentration of aflatoxin M1 (AFM1) in milk from Holstein-Friesian cows on local farms located in two different cities in Turkey, to investigate the effect of this mycotoxin on milk quality and seasonal variation, and to investigate the efficacy of a commercial clay-based binder. As part of the study, milk samples from 144 dairy cows were analyzed for the presence of AFM1 prior to the use of a clay-based toxin binder. As a result of this analysis, 26.9% of milk samples from individual animals had AFM1 levels exceeding the U.S. permissible limit of 0.5

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Leivo, Janne, Markus Vehniäinen, and Urpo Lamminmäki. "Phage Display Selection of an Anti-Idiotype-Antibody with Broad-Specificity to Deoxynivalenol Mycotoxins." Toxins 13, no. 1 (2020): 18. http://dx.doi.org/10.3390/toxins13010018.

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The use of synthetic antibody libraries and phage displays provides an efficient and robust method for the generation of antibodies against a wide range of targets with highly specific binding properties. As the in vitro selection conditions can be easily controlled, these methods enable the rapid generation of binders against difficult targets such as toxins and haptens. In this study, we used deoxynivalenol mycotoxin as a target to generate anti-idiotype-antibodies with unique binding properties from synthetic antibody libraries. The binding of the selected anti-idiotype antibodies can be ef

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Wei, Yi, Meng Sun, Jingjing Sun, Qiuyu Jiang, and Bingkun Zhang. "Effect of Dietary Supplementation of Mycotoxin Adsorbent on Laying Performance and Oviduct Health of Laying Hens in Aflatoxin B1 Exposed." Agriculture 14, no. 12 (2024): 2176. http://dx.doi.org/10.3390/agriculture14122176.

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Aflatoxin contamination causes huge economic losses in animal husbandry by inhibiting growth and performance. The addition of mycotoxin binders to contaminate diets has been widely used for mycotoxin removal. Bentonite and yeast cell walls have received increasing attention as efficient and low-cost adsorbents. This study utilizes a mycotoxin adsorbent (MAB) to bind Aflatoxin B1 (AFB1) in feed. The trial was a randomized trial design, with 240 forty-three-week-old Hy-line Brown laying hens allocated to four groups, and with 80 birds in each group. The three diets used in the experiment were: (

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