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Journal articles on the topic 'Myofibrome'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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1

Maradeix, S., and B. Cribier. "Myofibrome et myofibromatose." Annales de Dermatologie et de Vénéréologie 132, no. 3 (March 2005): 271–75. http://dx.doi.org/10.1016/s0151-9638(05)79263-2.

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2

Vitrey, F., J. P. Ory, D. Bourscheid, and C. Lebrun. "Polyglobulie et myofibrome utérin." La Revue de Médecine Interne 22 (June 2001): 125. http://dx.doi.org/10.1016/s0248-8663(01)83537-2.

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3

Ben Salem, A., S. Rammeh, S. Ben Taazayat, N. Znaidi, B. Fazaa, and R. Zermani. "Myofibrome solitaire de l’adulte." Annales de Dermatologie et de Vénéréologie 139, no. 11 (November 2012): 765–66. http://dx.doi.org/10.1016/j.annder.2012.04.190.

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4

Ben Haj Amor, M., E. Nectoux, D. Basraoui, M. Cagneaux, X. Leroy, B. Herbaux, F. Gabor, and N. Boutry. "Myofibrome calcifié solitaire de la jambe : à propos d’un cas." Journal de Radiologie 92, no. 3 (March 2011): 243–46. http://dx.doi.org/10.1016/j.jradio.2011.02.006.

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5

Huet, F., P. Plantin, C. Le Rouzic, L. Carausu, L. Misery, and C. Abasq-Thomas. "Myofibrome solitaire cervicofacial de découverte anténatale et de régression spontanée." Annales de Dermatologie et de Vénéréologie 143, no. 12 (December 2016): S306—S307. http://dx.doi.org/10.1016/j.annder.2016.09.461.

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6

Koo, Selene C., Katherine A. Janeway, Marian H. Harris, Christy J. Fryer, Jon C. Aster, Alyaa Al-Ibraheemi, and Alanna J. Church. "A Distinctive Genomic and Immunohistochemical Profile for NOTCH3 and PDGFRB in Myofibroma With Diagnostic and Therapeutic Implications." International Journal of Surgical Pathology 28, no. 2 (September 29, 2019): 128–37. http://dx.doi.org/10.1177/1066896919876703.

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Introduction. Myofibromas are rare tumors of pericytic lineage, typically affecting children, and are sometimes aggressive. A subset of sporadic and familial myofibromas have activating variants in PDGFRB. The relationship of myofibroma and PDGFRB to the NOTCH pathway has not yet been described. Methods. Ten myofibroma cases were sequenced with a targeted panel of 447 genes, including copy number variation and selected fusions. Immunohistochemical analysis of total NOTCH3 and activated NOTCH3 was assessed for all 10 myofibroma cases, and a series of histologic mimics (n = 20). Results. Alterations identified by next-generation sequencing included PDGFRB sequence variants in 8/10 cases (80%), a NOTCH3 variant in 1/10 cases (10%), and a NOTCH2 variant in 1/10 cases (10%). All 10 cases also showed a pattern of low-amplitude (1.5- to 2-fold) copy number alterations including gains in PDGFRB and NOTCH3. Ten of 10 myofibromas (100%) showed cytoplasmic staining for total NOTCH3 and 9 of 10 cases (90%) showed nuclear staining for activated NOTCH3. Within the control cohort of histologic mimics, 3 of 3 nodular fasciitis cases (100%) were positive for activated and total NOTCH3, and the remaining 17 cases were negative for pan NOTCH3, while 3 of 3 desmoid-type fibromatosis cases (100%) showed patchy weak nuclear staining for activated NOTCH3. Discussion. Our findings suggest a common pathway of PDGFRB/NOTCH3 activation in myofibromas, even in cases that lack PDGFRB sequence variants. These results support the pericytic lineage of myofibroma. Identification of the characteristic genomic alterations or immunohistochemical staining pattern may facilitate a difficult pathologic diagnosis, and support the use of targeted treatments.
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7

Capo, Joseph A., Dina Moubayed, Sami P. Moubayed, Juan C. Hernandez-Prera, Azita Khorsandi, Daniel Buchbinder, and Mark L. Urken. "Pediatric Myofibroma of the Palate with Ulceration and Bone Destruction." Case Reports in Otolaryngology 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/1432764.

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Myofibroma is a rare benign neoplasm occurring in the head and neck, arising primarily in infants and children. Frequently, myofibromas grow rapidly leading to suspicion of malignancy and the potential for overaggressive surgical excision. We aim to report a rare case of myofibroma with ulceration and bone destruction. A nine-year-old female presented with an ulcerated left hard palate mass. Open biopsy was performed with pathology suggestive of myofibroma. A left partial maxillectomy and reconstruction with a buccal advancement flap were performed. Final pathology confirmed the diagnosis of a benign myofibroma. Myofibroma is a rare benign tumor of the head and neck which must be considered in the differential diagnosis by the clinician and the pathologist in order to prevent inappropriate and/or overaggressive treatment.
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8

Savithri, Vindhya, Rakesh Suresh, Mahija Janardhanan, and Thara Aravind. "Oral myofibroma presenting as an aggressive gingival lesion." BMJ Case Reports 14, no. 5 (May 2021): e242700. http://dx.doi.org/10.1136/bcr-2021-242700.

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Myofibromas are benign neoplasms of myofibroblastic origin and rarely encountered in the oral cavity. Myofibroma may frequently grow rapidly leading to suspicion of malignancy. This may lead to a tendency for aggressive management. The histopathology of this tumour has similarity with other spindle cell tumours and often requires immunohistochemical staining for diagnosis. Here, we present a case of myofibroma in a 15-year-old female patient who reported with an aggressive gingival swelling and discuss the various histopathological differential diagnosis.
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9

Davies, Benjamin M., Daniel du Plessis, and Kanna K. Gnanalingham. "Myofibroma of the cervical spine presenting as brachialgia." Journal of Neurosurgery: Spine 21, no. 6 (December 2014): 916–18. http://dx.doi.org/10.3171/2014.8.spine131194.

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Myofibromas are rare, benign tumors of myofibroblasts. Their occurrence in adults, involving bone outside of the head and neck, is especially uncommon. The authors report the case of a 34-year-old woman who presented with left-sided brachialgia. Magnetic resonance imaging identified an expansile soft-tissue lesion of the C6–7 facet joint. En bloc resection via a left posterior midline approach was undertaken. Histopathological analysis confirmed the lesion to be a myofibroma. Brachialgia resolved following surgery and there is no evidence of recurrence at 20 months follow-up. Myofibroma is a rare cause of primary soft-tissue tumor of the spine. Surgical excision remains the mainstay of treatment.
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10

Narayen, Vaishali, Syed Afroz Ahmed, Charu Suri, and Shahela Tanveer. "Myofibroma of the Gingiva: A Rare Case Report and Literature Review." Case Reports in Dentistry 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/243894.

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Myofibromas are benign uncommon fibroblastic tumors of the soft tissue, bone, or internal organs affecting all ages. These lesions histopathologically may mimic many other soft tissue tumors of the oral cavity such as spindle cell tumors of neurogenic and smooth muscle cell origin, thus leading to misdiagnosis and mistreatment. This case report describes a rare benign tumor, which presented as a soft tissue swelling on posterior gingiva. Surgical excision of the lesion was carried out under local anaesthesia. Histopathologic and immunohistochemical examination confirmed the diagnosis of myofibroma. Myofibroma should be included in the clinical differential diagnosis of masses of the oral soft tissues; however immunohistochemical examination is essential to establish an accurate diagnosis.
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11

Sharifi, A., P. Sen, R. Lonsdale, and D. Pawaroo. "A rare case of a myofibroma presenting on the tongue." Annals of The Royal College of Surgeons of England 97, no. 4 (May 2015): e57-e60. http://dx.doi.org/10.1308/003588415x14181254789600.

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Myofibromas are benign neoplasms of myofibroblastic origin, rarely encountered in the oral cavity. Limited awareness of the clinical features of these lesions risks misdiagnosis of more sinister pathology. The objective of this report is to highlight the potential diversity of oral lesions by describing an uncommon presentation of a myofibroma. The case reveals the diagnostic difficulties encountered, along with postoperative complications, which exemplify the remarkable healing capacity of the oral cavity.
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12

Rowan, C., A. Farboud, J. Mitchard, and A. Trinidade. "An unusual myofibroblastic proliferation of the pinna." Journal of Laryngology & Otology 125, no. 4 (January 12, 2011): 415–17. http://dx.doi.org/10.1017/s0022215110002756.

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AbstractIntroduction:Myofibrosis of the ear is rare. Myofibromas are mesenchymal tumours which usually present in infancy but have been reported sporadically in adults.Objective:To present a rare case of trauma as a cause of pinnal myofibrosis.Design and method:Case report. A 29-year-old soldier suffered repeated trauma from helmet wear and sports, and presented to our clinic with an exquisitely painful lump in the anti-helix of the pinna.Results:The lump was excised uneventfully. Pathology revealed a reactive myofibroblastic proliferation which, given the history of trauma, raised the possibility of a florid cellular repair process. The main differential diagnosis was myofibroma. Immunohistochemistry was used to exclude other possible causes.Conclusion:No similar case has previously been reported. The aetiology of myofibroma is unclear, but repeated trauma may be a trigger. Histological and immunohistochemical analysis are recommended when the diagnosis is ambivalent.
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13

Pensabene, Marco, Fortunato Siracusa, Vito Rodolico, Giuseppe Li Voti, Elisa Zambaiti, and Marcello Cimador. "Solitary Myofibroma of the Bladder Trigone in a 3-Month-Old Patient: First Case Report." Case Reports in Pediatrics 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/1951840.

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Visceral solitary myofibromas are uncommon in childhood. We report a case of a solitary asymptomatic visceral myofibroma of the bladder trigone occurring in a 3-month-old boy. Once malignancies were ruled out by cystoscopy, radical excision was performed in order to avoid any potential impairment of bladder dynamic. Postoperative course was uneventful and patient was discharged on day 3 after surgery. After 36 months of follow-up, the patient is toilet-trained and remains well; bladder function is normal.
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14

Marechal, C., L. Laccourreye, I. Pellier, O. Couturier, C. Lamirel, and I. Cochereau. "358 Tomographie par Emission de Positons (TEP) dans les tumeurs orbitaires de l’enfant : à propos d’un cas de myofibrome." Journal Français d'Ophtalmologie 31 (April 2008): 121. http://dx.doi.org/10.1016/s0181-5512(08)70956-2.

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15

Ivanov, Alexander, Tibor Valyi-Nagy, and Dimitrios Nikas. "Extracalvarial Composite Infantile Myofibromatosis: Case Report and Literature Review." European Journal of Pediatric Surgery Reports 04, no. 01 (June 12, 2016): 022–25. http://dx.doi.org/10.1055/s-0036-1580704.

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Infantile soft tissue tumors of the head are very rare and the majority of them are myofibromas. The authors present the case of a 1-day-old boy with a scalp tumor with several distinct histopathological features including myofibroma, hemangiopericytoma, and fibrosarcoma consistent with the diagnosis of composite infantile myofibromatosis. Genetic testing was negative for trisomy 17, translocation (12; 15), FUS, and ETV6 translocations. Despite the ominous histopathological features, the clinical course was benign. The authors review here available literature concerning current concepts of making the diagnosis of composite infantile myofibromatosis and discuss treatment options.
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16

Koyuncu, Banu Özveri, Mert Zeytinoğlu, Taha Ünal, and Bülent Zeytinoğlu. "Myofibroma of the Gingiva: Report of a Case." Journal of Clinical Pediatric Dentistry 34, no. 3 (April 1, 2010): 253–57. http://dx.doi.org/10.17796/jcpd.34.3.w746852328uxj577.

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Myofibroma is a benign mesenchymal neoplasm composed of myofibroblasts which has been described with different synonyms since the first report in 1951. It occurs most commonly as a solitary lesion of soft tissue,skin, or bone in infancy. The prognosis of oral myofibromas is excellent, and surgical excision is curative. Recurrence is rare. Awareness and recognition of this benign tumor is important to establish the correct diagnosis and avoid morbidity of unnecessary aggressive therapy. This report describes a myofibroma of the gingiva in a 14 year old girl and is reported together with the conventional histologic, and immunohistochemical findings. The tumor showed rapid increase in size and clinical features suggestive of malignancy. However, on histopathologic evaluation it was diagnosed as a benign neoplasm, and this diagnosis was supported by immunohistochemical markers. The spindle cells were immunopositive for smooth muscle actin,and vimentin but were negative for desmin and S-100 protein. The patient was treated with surgical excision,and is followed-up for 33 months without any signs of recurrence.
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17

Fine, Samson W., North J. Davis, Lawrence E. Lykins, and Elizabeth Montgomery. "Solitary Testicular Myofibroma: A Case Report and Review of the Literature." Archives of Pathology & Laboratory Medicine 129, no. 10 (October 1, 2005): 1322–25. http://dx.doi.org/10.5858/2005-129-1322-stmacr.

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Abstract Myofibromas are benign mesenchymal neoplasms of myofibroblastic origin. Most present as solitary lesions at any age, but the presentation of multiple lesions in newborns and infants is known as infantile myofibromatosis. Multicentric lesions commonly involve soft tissues and bone and may involve internal organs, where they are associated with an unfavorable prognosis. Solitary lesions involving the viscera are rare. We report a case of a 3-month-old male infant with a left testicular mass detected during an evaluation for suspected torsion. The patient underwent orchiectomy, revealing a nodular mass with grossly evident foci of necrosis. Histologically, the lesion exhibited small fascicles of plump eosinophilic, smooth muscle actin–positive spindle cells, alternating with larger areas of primitive cells with vesicular nuclei and scant cytoplasm arranged around a hemangiopericytoma-like vasculature. To our knowledge, this is the first report of a myofibroma localized within the testis.
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18

Ottenhoff, Janna S. E., Peter G. J. Nikkels, C. E. J. Terwisscha van Scheltinga, and L. Naeije. "A Solitary Intestinal Myofibroma: A Rare Cause of Neonatal Anemia." Case Reports in Oncology 10, no. 3 (October 17, 2017): 890–96. http://dx.doi.org/10.1159/000481305.

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Solitary infantile myofibroma with visceral involvement is very rare. We present an unusual case of a solitary myofibroma with abdominal localization in a 1-day-old female neonate who presented with severe anemia and rectal bleeding. A bleeding myofibroma was found, located in the wall of the jejunum, and totally resected. In case of a solitary lesion, treatment is relatively easy and effective, with excellent prognosis after total resection. The multiple form (myofibromatosis) has a poor prognosis with low survival rates. We therefore recommend total body MRI for all patients diagnosed with myofibroma to rule out other lesions.
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19

Schurr, Patti, and Wendy Moulsdale. "Infantile Myofibroma." Advances in Neonatal Care 8, no. 1 (February 2008): 13–20. http://dx.doi.org/10.1097/01.anc.0000311012.63887.fb.

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20

Bowen, Anneli R., and Cheryl M. Coffin. "Infantile Myofibroma." Pathology Case Reviews 14, no. 3 (May 2009): 110–13. http://dx.doi.org/10.1097/pcr.0b013e3181a6ecc9.

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21

Thennavan, Aatish, Venkadasalapathi Narayanaswamy, Thanvir Mohammed Niazi, Lakshmi Rao, and Raghu Radhakrishnan. "Infantile Myofibroma Eroding into the Frontal Bone: A Case Report and Review of Its Histopathologic Differential Diagnosis." Case Reports in Pediatrics 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/630804.

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Infantile myofibroma is a rare and benign tumour of children presenting in the head and neck region. Rendering a final diagnosis of infantile myofibroma can be challenging in the light of nonspecific clinical, radiological findings and its histopathological similarities with a number of neoplasms especially spindle cell tumours. In this paper we discuss a case of infantile myofibroma in a 2-month-old infant, enumerating the various differential entities that have to be eliminated in reaching its specific diagnosis and highlighting the importance of immunopositivity to vimentin and smooth muscle actin (SMA) in establishing its myofibroblastic differentiation.
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22

Kharkar, V., U. Khopkar, and V. Patel. "Adult cutaneous myofibroma." Indian Journal of Dermatology, Venereology and Leprology 74, no. 1 (2008): 56. http://dx.doi.org/10.4103/0378-6323.38412.

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23

Mbekeani, Joyce N., Jean Louis Kemeny, and Hachemi Nezzar. "Infantile orbital myofibroma." International Journal of Pediatrics and Adolescent Medicine 2, no. 1 (March 2015): 44–46. http://dx.doi.org/10.1016/j.ijpam.2015.03.006.

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24

Ide, Fumio. "Oral solitary myofibroma." Journal of Oral Pathology & Medicine 37, no. 1 (June 25, 2007): 62. http://dx.doi.org/10.1111/j.1600-0714.2007.00576.x.

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25

Coleman, Alan M., Maria A. Calvo-Garcia, Andrew M. Zbojniewicz, Maria Alonso, and Foong-Yen Lim. "Prenatal Diagnosis of Infantile Myofibroma with Postnatal Imaging Correlation." Fetal Diagnosis and Therapy 40, no. 1 (August 14, 2014): 73–78. http://dx.doi.org/10.1159/000365213.

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Infantile myofibroma is the most common fibrous tumor in infancy. A majority of these lesions are solitary and occur in the head and neck region. Unless visceral sites are involved, the clinical course is typically benign. However, the difficulty in these cases is the differentiation of a benign myofibroma from a solitary malignant neoplasm and determination of visceral involvement. Prenatal diagnosis of this condition is rarely described in the literature, but it does indeed have a role in perinatal management. Our patient was initially identified by prenatal ultrasound with fetal MRI for further characterization of the mass. We present the case of a prenatally diagnosed solitary infantile myofibroma of the lower extremity and highlight the role of prenatal imaging in the diagnosis and treatment of this condition.
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26

Balakrishnan, R., Kailesh Pujary, Parul Shah, and Produl Hazarika. "Solitary adult myofibroma of the pinna." Journal of Laryngology & Otology 113, no. 2 (February 1999): 155–57. http://dx.doi.org/10.1017/s0022215100143439.

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AbstractSolitary myofibroma is a recently described benign neoplasm of the skin or superficial soft tissue and it represents the adult counterpart of infantile myofibromatosis. This new clinicopathological entity is being recognized increasingly. A case of solitary myofibroma occurring in the pinna of a 50-year-old woman is presented. Such a lesion occurring in the pinna of an adult has not been reported in the literature.
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27

Sugatani, Toshifumi, Madoka Inui, Toshiro Tagawa, Yutaka Seki, Atsusi Mori, and Joji Yoneda. "Myofibroma of the mandible." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 80, no. 3 (September 1995): 303–9. http://dx.doi.org/10.1016/s1079-2104(05)80388-9.

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28

PIRES, VICTOR HUGO ALBERT, ALBERES KENIO DA SILVA DE ANDRADE, THALLES M. SUASSUNA, ELAINE JUDITE DE AMORIM CARVALHO, JUREMA FREIRE LISBOA DE CASTRO, and DANYEL ELIAS DA CRUZ PEREZ. "PP - SOLITARY INFANTILE MYOFIBROMA." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 123, no. 2 (February 2017): e72. http://dx.doi.org/10.1016/j.oooo.2016.09.175.

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29

Yazici, Bülent, Ayse Dolar Bilge, Zeynep Yazici, and Ulviye Yalçinkaya. "Congenital Cranio-Orbital Myofibroma." Ophthalmic Plastic & Reconstructive Surgery 27, no. 4 (July 2011): e108-e111. http://dx.doi.org/10.1097/iop.0b013e3181fc05f8.

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30

Erdem, Zeynep Betül, Özben Yalçın, and Ayşe Tülay Sayılgan. "İnfantil Myofibrom: Olgu Sunumu." Maltepe Tıp Dergisi 11, no. 3 (December 30, 2019): 81–84. http://dx.doi.org/10.35514/mtd.2019.17.

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31

Chowalta, Rajat, Paramjeet Kaur, and Jeevan Lata. "Central myofibroma of the maxilla." Contemporary Clinical Dentistry 7, no. 1 (2016): 71. http://dx.doi.org/10.4103/0976-237x.177109.

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32

WERNECK, JULIANA TRISTÃO, ANA MARIA BEZERRA BANDEIRA, WLADIMIR CORTEZZI, NATALIE HENRIQUES CANEDO, MÁRIO JOSÉ ROMAÑACH GONZALEZ SOBRINHO, VALDIR MEIRELLES, and MARIA ELISA RANGEL JANINI. "Extensive Myofibroma in Pediatric Patient." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 120, no. 2 (August 2015): e79. http://dx.doi.org/10.1016/j.oooo.2015.02.352.

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33

Lemos, Wilbênia Pontes, Adriana Souza De Jesus, Leandro Santiago Lima, Pablyanne Tereza Louzada Guedes, Douglas Magno Guimarães, Flávia Sirotheau Corrêa Pontes, and Hélder Antônio Rebelo Pontes. "Case Report: Benign Tumor Myofibroma." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 126, no. 3 (September 2018): e79. http://dx.doi.org/10.1016/j.oooo.2018.02.226.

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34

Sánchez-MarIan, Luis Alberto, Héctor Prado-Calleros, Daniel Bross-Soriano, José Arrieta-Gómez, and E. Germán Recinos-Carrera. "Juvenile Myofibroma of the Neck." Otolaryngology–Head and Neck Surgery 133, no. 4 (October 2005): 642. http://dx.doi.org/10.1016/j.otohns.2004.09.095.

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35

Diplomatico, Mario, Francesco Esposito, Ferdinando Aliberti, Pierluigi Marzuillo, Maria Elena Errico, and Orsola Ametrano. "Myofibroma—A Common Congenital Lesion." Journal of Pediatrics 213 (October 2019): 245–245. http://dx.doi.org/10.1016/j.jpeds.2019.05.021.

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36

GORISCH, MARCIA RODRIGUES, ROSANA MARA GIORDANO DE BARROS, EDUARDO GIORDANO DE BARROS, and SILVIA ROBERTA CIESLAK. "Myofibroma in Childhood: Case Report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 117, no. 2 (February 2014): e174. http://dx.doi.org/10.1016/j.oooo.2013.12.128.

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37

Çubuk, Seçil, Eda Yılmaz Akcay, Esra Beyler, and Burak Bayram. "Myofibroma in Palate: Case Report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 119, no. 3 (March 2015): e201. http://dx.doi.org/10.1016/j.oooo.2014.07.438.

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38

Friis, Jakob, Soren Daugaard, Steffen Heegaard, Lise Grupe Larsen, Jan Ulrik Prause, and Peter Schmidt. "Solitary myofibroma of the eyelid." Acta Ophthalmologica Scandinavica 82, no. 1 (February 2004): 109–11. http://dx.doi.org/10.1111/j.1395-3907.2004.0189e.x.

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39

Mahajan, Priya, John Hicks, Murali Chintagumpala, and Rajkumar Venkatramani. "Myofibroma in Infancy and Childhood." Journal of Pediatric Hematology/Oncology 39, no. 3 (April 2017): e136-e139. http://dx.doi.org/10.1097/mph.0000000000000732.

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40

Merrell, Stephen C., Reza Rahbar, Ahmad I. Alomari, Horacio M. Padua, Sara O. Vargas, Ellis J. Neufeld, Jennifer L. Dearden, John B. Mulliken, and Arin K. Greene. "Infantile Myofibroma or Lymphatic Malformation." Journal of Craniofacial Surgery 21, no. 2 (March 2010): 422–26. http://dx.doi.org/10.1097/scs.0b013e3181cfa777.

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41

Heitz, Claiton, Roger Correa de Barros Berthold, Heloísa Har Machado, Lucas Sant’Ana, and Rogério Belle de Oliveira. "Submandibular myofibroma: a case report." Oral and Maxillofacial Surgery 18, no. 1 (February 13, 2013): 81–86. http://dx.doi.org/10.1007/s10006-013-0388-3.

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42

Fuchs, Juri, Patrick Günther, Abdulsattar Alrajab, Ahmed El Damaty, Wiebke Antonopoulos, and Patrick Volk. "Congenital myofibroma of the pericranium." Journal of Pediatric Surgery Case Reports 62 (November 2020): 101629. http://dx.doi.org/10.1016/j.epsc.2020.101629.

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43

Choopong, Pitipol, Petur G. Nielsen, Elliot M. Perlman, John J. Huang, Thaddeus P. Dryja, and C. Stephen Foster. "Solitary Myofibroma of the Sclera." Cornea 26, no. 1 (January 2007): 114–16. http://dx.doi.org/10.1097/01.ico.0000243951.07096.fd.

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44

Bala Sundram, Meshala, Navasheilla Retna Retnasingam, Bahruddin Saripudin, and Zuraiza Mohamad Zaini. "Intraosseous Myofibroma of the Mandible in a 7-Year-Old Patient: A Case Report." Malaysian Journal of Paediatrics and Child Health 27, no. 1 (January 25, 2021): 1–7. http://dx.doi.org/10.51407/mjpch.v27i1.117.

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Myofibroma is a benign fibrous tumour that occurs predominantly in the head and neck region followed by the trunk and extremities. However, cases occurring in the oral cavity are rare, presenting with a variable clinical appearances and wide differential diagnosis. We reported a case of a 7-year-old girl who was referred to the Department of Paediatric Dentistry, Tengku Ampuan Rahimah Hospital with a progressively enlarging painless swelling on the left posterior region of the mandible over the past 3 months. The swelling was associated with ulceration and displaced lower left first permanent molar. Radiographic investigations reported well-defined radiolucency at molar area, alveolar expansion and bone resorption of the left posterior alveolar ridge of the mandible. Complete surgical excision of the lesion was performed under general anaesthesia. Histopathological examination revealed proliferation of spindle shaped cells with biphasic growth pattern. Immunohistochemical staining showed strong positivity with vimentin and smooth muscle actin whilst negative for desmin, S100 and CD34 establishing the diagnosis of myofibroma. Although rare, myofibroma should be considered as a differential diagnosis for solitary firm swelling in the oral cavity. Histopathological examination together with immunohistochemical analysis is essential for an accurate diagnosis.
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45

Guan, Debao, Jiang Yao, Xiaoyu Luo, and Hao Gao. "Effect of myofibre architecture on ventricular pump function by using a neonatal porcine heart model: from DT-MRI to rule-based methods." Royal Society Open Science 7, no. 4 (April 2020): 191655. http://dx.doi.org/10.1098/rsos.191655.

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Myofibre architecture is one of the essential components when constructing personalized cardiac models. In this study, we develop a neonatal porcine bi-ventricle model with three different myofibre architectures for the left ventricle (LV). The most realistic one is derived from ex vivo diffusion tensor magnetic resonance imaging, and other two simplifications are based on rule-based methods (RBM): one is regionally dependent by dividing the LV into 17 segments, each with different myofibre angles, and the other is more simplified by assigning a set of myofibre angles across the whole ventricle. Results from different myofibre architectures are compared in terms of cardiac pump function. We show that the model with the most realistic myofibre architecture can produce larger cardiac output, higher ejection fraction and larger apical twist compared with those of the rule-based models under the same pre/after-loads. Our results also reveal that when the cross-fibre contraction is included, the active stress seems to play a dual role: its sheet-normal component enhances the ventricular contraction while its sheet component does the opposite. We further show that by including non-symmetric fibre dispersion using a general structural tensor, even the most simplified rule-based myofibre model can achieve similar pump function as the most realistic one, and cross-fibre contraction components can be determined from this non-symmetric dispersion approach. Thus, our study highlights the importance of including myofibre dispersion in cardiac modelling if RBM are used, especially in personalized models.
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46

McCoard, S. A., W. C. McNabb, S. W. Peterson, S. N. McCutcheon, and P. M. Harris. "Muscle growth, cell number, type and morphometry in single and twin fetal lambs during mid to late gestation." Reproduction, Fertility and Development 12, no. 6 (2000): 319. http://dx.doi.org/10.1071/rd99059.

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Muscle growth, myofibre number, type and morphometry were studied in large hindlimb muscles of single and twin fetal lambs during mid to late gestation. Placental insufficiency, evident by lower total placentome weight and number per fetus, resulted in reduced fetal weights from 100 to 140 days gestation in twins compared with singletons (at 140 days: 5016 108 g v. 5750 246 g, respectively; P<0.05). However, competition between littermates did not consistently reduce muscle mass (15–22%) until 140 days gestation. Apparent myofibre number increased with age, indicating that the full complement of myofibres in some large hindlimb muscles may be achieved during early postnatal life. Litter size did not impact on apparent myofibre number in the semitendinosus, plantaris or gastrocnemius muscles. However, a transient effect on myofibre number in the adductor femoris muscle was observed from 80–120 days gestation. The phenotypic maturation of myofibres was unaffected by increasing litter size. Smaller muscle mass in twins was associated with smaller myofibre cross-sectional area in the semitendinosus, adductor femoris and gastrocnemius muscles at 140 days gestation. A similar trend was observed for the plantaris muscle. These results indicate that while competition between littermates for nutrients in late gestation can impact on both fetal and muscle mass, the fetus has the capacity to buffer against the effects of restricted nutrient supply on myofibre hyperplasia and phenotypic maturation, but myofibre hypertrophy is compromised.
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47

Nirvikalpa, Natarajan, and Vinod Narayanan. "Intraosseous infantile myofibroma of the mandible." Annals of Maxillofacial Surgery 1, no. 1 (2011): 87. http://dx.doi.org/10.4103/2231-0746.83151.

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48

Karasu, M. Fatih, Imdat Yuce, Sedat Cagli, Ramazan Gundogdu, Mesut Aydin, Turhan Okten, and Ercihan Guney. "Myofibroma in the Upper Jugular Region." Erciyes Tıp Dergisi/Erciyes Medical Journal 35, no. 3 (September 12, 2013): 181–83. http://dx.doi.org/10.5152/etd.2013.30.

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49

Nowair, Ibrahim, Mohamed Eid, Basant AbouZaid, and Heba Youssef. "Infantile Central Myofibroma of the Mandible:." Egyptian Journal of Oral and Maxillofacial Surgery 10, no. 2 (April 1, 2019): 58–63. http://dx.doi.org/10.21608/omx.2019.19202.1042.

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50

Souza, Denis P., Caio C. S. Loureiro, Roberto A. G. Rejas, Suzana O. M. Sousa, and Ricardo Raitz. "Intraosseous myofibroma simulating an odontogenic lesion." Journal of Oral Science 51, no. 2 (2009): 307–11. http://dx.doi.org/10.2334/josnusd.51.307.

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