Academic literature on the topic 'N-Benzyl benzylamines'

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Journal articles on the topic "N-Benzyl benzylamines"

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Neeraj, Rani, R. Sharma J., K. Kaul V., and R. Manrao M. "Secondary amines : Synthesis and effect of length of spacer linking two phenyl rings on biological activity." Journal of Indian Chemical Society Vol. 85, Oct 2008 (2008): 1041–44. https://doi.org/10.5281/zenodo.5820670.

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Department of Chemistry, Department of Plant Pathology, Punjab Agricultural University, Ludhiana-141 004, Punjab, India <em>Manuscript received 7 January 2008, revised 30 June 2008, accepted 16 July 2008</em> N-Benzyl benzylamines (1a-11a) and N-benzyl anilines (1b-11b) were synthesized by sodium borohydride reduction of aldimines of benzylamine and aniline respectively. The products were characterized on the basis of elemental analysis and spectral studies and screened for antifungal potential against four fungi and evaluated for nematicidal activity against two nematodes. The former compound
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Ramkumar, Nagarajan, and Rajagopal Nagarajan. "Formal total synthesis of calothrixin B and its N-benzyl analogues." RSC Advances 5, no. 107 (2015): 87838–40. http://dx.doi.org/10.1039/c5ra18120h.

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Galletti, P., G. Martelli, G. Prandini, C. Colucci, and D. Giacomini. "Sodium periodate/TEMPO as a selective and efficient system for amine oxidation." RSC Advances 8, no. 18 (2018): 9723–30. http://dx.doi.org/10.1039/c8ra01365a.

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Dama, Habila J., Kandappa H. Reddy, Patrick Govender, and Neil A. Koorbanally. "Synthesis and Antifungal Studies of (2E)-N-Benzyl-N′-phenylbut-2-enediamide and (2E)-N,N′-Dibenzylbut-2-enediamide Analogues." Journal of Chemistry 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/281341.

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A series of eleven butanediamine analogues, of which nine were new, were synthesized by the nucleophilic substitution of aromatic amines and benzylamines with maleic anhydride and tested on four yeast strains ofCandidaspecies using the broth microdilution method. Compounds3aand3cwith an unsubstituted phenyl ring and a 3-methoxyphenyl ring, respectively, are the most active against the fungal species with MIC values ranging from 20.2 to 80.6 μM forC. albicansandC. parapsilosisand 178.5 and 161.2 μM forC. krusei, respectively.
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Rádl, Stanislav, Jan Stach, Josef Černý, and Ondřej Klecán. "An efficient synthesis of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine, a key intermediate in the licofelone synthesis." Collection of Czechoslovak Chemical Communications 74, no. 6 (2009): 1011–22. http://dx.doi.org/10.1135/cccc2009026.

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An efficient synthesis of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine, a key intermediate for the synthesis of licofelone, an anti-inflammatory drug currently undergoing evaluation of the phase-III clinical studies, is described. The method is based on a novel synthesis of unstable 5-benzyl-3,3-dimethyl-3,4-dihydro-2H-pyrrole, which is then treated with 2-bromo-1-(4-chlorophenyl)ethan-1-one. 2,2-Dimethyl-5-phenylpent-4-ynal with benzylamines provides the corresponding Schiff bases. Migration of the C=N double bond in these N-(2,2-dimethyl-5-phenylpent-4-yn-1-ylidene)ben
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Laha, Joydev K., Pankaj Gupta, and Amitava Hazra. "Sulfate radical anion-induced benzylic oxidation of N-(arylsulfonyl)benzylamines to N-arylsulfonylimines." Beilstein Journal of Organic Chemistry 19 (June 5, 2023): 771–77. http://dx.doi.org/10.3762/bjoc.19.57.

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A mild, operationally convenient, and practical method for the synthesis of synthetically useful N-arylsulfonylimines from N-(arylsulfonyl)benzylamines using K2S2O8 in the presence of pyridine as a base is reported herein. In addition, a “one-pot” tandem synthesis of pharmaceutically relevant N-heterocycles by the reaction of N-arylsulfonylimines, generated in situ with ortho-substituted anilines is also reported. The key features of the protocol include the use of a green oxidant, a short reaction time (30 min), chromatography-free isolation, scalability, and economical, delivering N-arylsulf
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Kim, Sung Soo, and Hwan Kyu Jung. "OxidativeN-debenzylation ofN-benzyl-N-substituted benzylamines catalyzed by horseradish peroxidase." Journal of Physical Organic Chemistry 16, no. 8 (2003): 555–58. http://dx.doi.org/10.1002/poc.648.

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Ulgen, Mert, and John W. Gorrod. "The Failure of Substrate pKa to Influence the Microsomal Formation of Amides from N-Benzylamines: the Microsomal Metabolism of N-Benzyl Pyrrolidine, N-Benzyl Carbazole and N-Acetyl-N-benzyl-4-methylaniline." Journal of Pharmacy and Pharmacology 48, no. 12 (1996): 1320–26. http://dx.doi.org/10.1111/j.2042-7158.1996.tb03943.x.

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Mlostoń, Grzegorz, Mateusz Kowalczyk, Małgorzata Celeda, Marcin Jasiński, Marta Denel-Bobrowska, and Agnieszka B. Olejniczak. "Fluorinated Analogues of Lepidilines A and C: Synthesis and Screening of Their Anticancer and Antiviral Activity." Molecules 27, no. 11 (2022): 3524. http://dx.doi.org/10.3390/molecules27113524.

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Starting with fluorinated benzylamines, a series of 2-unsubstituted imidazole N-oxides was prepared and subsequently deoxygenated in order to prepare the corresponding imidazoles. The latter were treated with benzyl halides yielding imidazolium salts, which are considered fluorinated analogues of naturally occurring imidazolium alkaloids known as lepidilines A and C. A second series of oxa-lepidiline analogues was obtained by O-benzylation of the initially synthetized imidazole N-oxides. Both series of imidazolium salts were tested as anticancer and antiviral agents. The obtained results demon
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Patel, Srilaxmi M., Harika Chada, Sonali Biswal, Sonika Sharma та Duddu S. Sharada. "Copper-Catalyzed Intramolecular α-C–H Amination via Ring-Opening Cyclization Strategy to Quinazolin-4-ones: Development and Application in Rutaecarpine Synthesis". Synthesis 51, № 16 (2019): 3160–70. http://dx.doi.org/10.1055/s-0037-1611575.

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A copper-catalyzed intramolecular α-C–H amination has been developed for the synthesis of quinazolin-4(3H)-one derivatives from commercially available isatoic anhydride and primary and secondary benzylamines via ring-opening cyclization (ROC). This method shows good functional group tolerance and allows access to a range of 2-aryl, 2-alkyl, and spiroquinazolinone derivatives. However, 2-methylquinazolin-4(3H)-one was synthesized from 2-amino-N-isopropylbenzamide by C–C bond cleavage, and N-benzyl-2-(methylamino)benzamide afforded 1-methyl-2-phenylquinazolin-4(1H)-one along with 2-phenylquinazo
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Dissertations / Theses on the topic "N-Benzyl benzylamines"

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Kanazawa, Alice Misa. "Nouvelles synthèses de chaînes latérales du taxotère et du taxol et synthèses du (+ou-)- et (-)-homogynolide-A." Grenoble 1, 1994. http://www.theses.fr/1994GRE10008.

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Le taxol et le taxotere sont deux composes qui presentent des activites antitumorales assez remarquables contre plusieurs types de cancers. La synthese partielle en utilisant un produit naturel abondant et les chaines laterales correspondantes est la strategie de choix actuelle pour l'obtention de facon efficace de ces deux composes. Un des interets majeurs du laboratoire consiste a trouver de nouvelles methodes de synthese de ces chaines (surtout du taxotere) sous forme enantiomeriquement pure. Au cours de ce travail nous avons effectue, dans un premier temps, une synthese courte et directe (
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Li, Shih-Liang, and 李世良. "Synthesis and Biological Activity of Ethyl 2- [N-substituted benzyl]benzylamino-4-oxo-4,5-dihydrofuran-3-carboxylate and related compounds." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/77331452477449678165.

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碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>95<br>A series of ethyl 2- [N-substituted benzyl]benzylamino-4-oxo-4,5-dihydrofuran-3-carboxylate and related compounds has been synthesized and assigned by their spectra data. All of these synthetic compound were evaluated for biological activities(anti-arrhythmics activity、cardiovascular effect、Reactive oxygen species antagonist、induces apotosis、anticancer activite). Among the investigations of the inhibitory effect on the heart rate , Ethyl 2-(N-o-fluorobenzyl)benzylamino-4-oxo-4,5-dihydrofuran-3- carboxylate(6)、Ethyl 2-(N′-m-methylbenzyl)phenylhydrazino-4-
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