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Relevant bibliographies by topics / N-butyl deoxynojirimycin

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Journal articles
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Academic literature on the topic 'N-butyl deoxynojirimycin'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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Journal articles on the topic "N-butyl deoxynojirimycin"

1

Matos, Carlos R. R., Rosangela S. C. Lopes, and Claudio C. Lopes. "Synthesis of 1-Deoxynojirimycin and N-Butyl-1-deoxynojirimycin." Synthesis 1999, no. 04 (1999): 571–73. http://dx.doi.org/10.1055/s-1999-3430.

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2

Matos, Carlos R. R., Rosangela S. C. Lopes, and Claudio C. Lopes. "ChemInform Abstract: Synthesis of 1-Deoxynojirimycin and N-Butyl-1-deoxynojirimycin." ChemInform 30, no. 31 (2010): no. http://dx.doi.org/10.1002/chin.199931249.

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3

Wang, Jiajia, Yunyan Zhao, Wei Zhao, Peng Wang, and Jing Li. "Total synthesis of N-butyl-1-deoxynojirimycin." Journal of Carbohydrate Chemistry 35, no. 8-9 (2016): 445–54. http://dx.doi.org/10.1080/07328303.2017.1330415.

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4

Mehta, Anand, Serguey Ouzounov, Robert Jordan, et al. "Imino Sugars That are Less Toxic but More Potent as Antivirals, In Vitro, Compared with N-n-Nonyl DNJ." Antiviral Chemistry and Chemotherapy 13, no. 5 (2002): 299–304. http://dx.doi.org/10.1177/095632020201300505.

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Imino sugar glucosidase inhibitors have selective antiviral activity against certain enveloped, mammalian viruses. Deoxynojirimycins (DNJs) modified by N-alkylation to contain a nine carbon atom side chain (N-n-nonyl-deoxynojirimycin; N-nonyl-DNJ, NN-DNJ) were shown to be, for example, at least 20 times more potent in inhibiting hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) in cell based assays than the non-alkylated DNJ. These data suggested that modification of the alkyl side chain could influence antiviral activity. Previous work has focused on varying side chain length. I

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Boudewyn, Lauren C., Jakub Sikora, Ladislav Kuchar, Jana Ledvinova, and Steven U. Walkley. "Assessment of n-butyl-deoxynojirimycin as a therapeutic option for mucolipidosis type IV." Molecular Genetics and Metabolism 117, no. 2 (2016): S29. http://dx.doi.org/10.1016/j.ymgme.2015.12.204.

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6

Woodhouse, Stephen D., Caroline Smith, Maud Michelet, et al. "Iminosugars in Combination with Interferon and Ribavirin Permanently Eradicate Noncytopathic Bovine Viral Diarrhea Virus from Persistently Infected Cells." Antimicrobial Agents and Chemotherapy 52, no. 5 (2008): 1820–28. http://dx.doi.org/10.1128/aac.01181-07.

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ABSTRACT We evaluated interferon (IFN) and ribavirin (RBV) as dual therapy and as part of triple-combination therapies with the iminosugars N-butyl-deoxynojirimycin (NB-DNJ), N-nonyl-deoxynojirimycin, and N-7-oxanonyl-6-deoxymethyl-galactonojirimycin. The ability of these compounds to clear bovine viral diarrhea virus (BVDV), a surrogate model for hepatitis C virus (HCV), from a persistently infected Madin-Darby bovine kidney cells cell line was determined by monitoring the secretion of viral RNA and the infectivity of secreted virions. In the BVDV system, after treatment with IFN-RBV alone, v

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7

Chang, Jinhong, Lijuan Wang, Dongling Ma, et al. "Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses." Antimicrobial Agents and Chemotherapy 53, no. 4 (2009): 1501–8. http://dx.doi.org/10.1128/aac.01457-08.

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ABSTRACT Imino sugars, such as N-butyl-deoxynojirimycin and N-nonyl-deoxynojirimycin (NNDNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II in the endoplasmic reticulum and exhibit antiviral activities against many types of enveloped viruses. Although these molecules have broad-spectrum antiviral activity, their development has been limited by a lack of efficacy and/or selectivity. We have previously reported that a DNJ derivative with a hydroxylated cyclohexyl side chain, called OSL-95II, has an antiviral efficacy similar to that of NNDNJ but significantly les

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8

Tierney, M., J. Pottage, H. Kessler, et al. "The Tolerability and Pharmacokinetics of N-Butyl-deoxynojirimycin in Patients with Advanced HIV Disease (ACTG 100)." Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology 10, no. 5 (1995): 549–53. http://dx.doi.org/10.1097/00042560-199510050-00008.

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Tierney, M., J. Pottage, H. Kessler, et al. "The Tolerability and Pharmacokinetics of N-Butyl-deoxynojirimycin in Patients with Advanced HIV Disease (ACTG 100)." Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology 10, no. 5 (1995): 549–53. http://dx.doi.org/10.1097/00042560-199512050-00008.

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10

Ribas, Graziela S., Ricardo Pires, Janice Carneiro Coelho, et al. "Oxidative stress in Niemann‐Pick type C patients: a protective role of N‐butyl‐deoxynojirimycin therapy." International Journal of Developmental Neuroscience 30, no. 6 (2012): 439–44. http://dx.doi.org/10.1016/j.ijdevneu.2012.07.002.

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Dissertations / Theses on the topic "N-butyl deoxynojirimycin"

1

Amiri, Mahdi [Verfasser]. "The role of N-butyl deoxynojirimycin in enzyme function, membrane association and targeting of brush border hydrolases / Mahdi Amiri." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2014. http://d-nb.info/1064861679/34.

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Spiro, Simon George. "The mechanism of action of iminosugars as antiretrovirals." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:7fc4ae01-bdec-49d0-afec-e0f3e9e8f41d.

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Book chapters on the topic "N-butyl deoxynojirimycin"

1

Scaros, Mike G., Michael L. Prunier, Rick J. Rutter, Peter K. Yonan, Roy Grabner, and Bryan Landis. "A New and Improved Synthesis of N-Butyl-1 -Deoxynojirimycin." In Catalysis of Organic Reactions. CRC Press, 2020. http://dx.doi.org/10.1201/9781003067184-3.

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