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Relevant bibliographies by topics / N-glycosylation

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Academic literature on the topic 'N-glycosylation'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "N-glycosylation"

1

Pasing, Yvonne, Albert Sickmann, and Urs Lewandrowski. "N-glycoproteomics: mass spectrometry-based glycosylation site annotation." Biological Chemistry 393, no. 4 (2012): 249–58. http://dx.doi.org/10.1515/hsz-2011-0245.

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Abstract Glycosylations are ubiquitous and, in many cases, essential protein modifications. Yet comprehensive and detailed analysis of glycosylations on a proteome-wide scale is a daunting and still unsolved challenge. However, a common workflow has emerged over the last decade for large-scale N-glycosylation site annotation by application of proteomic methodology. Thereby, the qualitative and quantitative assessment of hundreds or thousands of modification sites is enabled. This review presents a short overview about common enrichment techniques and glycosylation site detection for N-glycopep

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Dobrica, Mihaela-Olivia, Catalin Lazar, and Norica Branza-Nichita. "N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis." Cells 9, no. 6 (2020): 1404. http://dx.doi.org/10.3390/cells9061404.

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Hepatitis B Virus (HBV) glycobiology has been an area of intensive research in the last decades and continues to be an attractive topic due to the multiple roles that N-glycosylation in particular plays in the virus life-cycle and its interaction with the host that are still being discovered. The three HBV envelope glycoproteins, small (S), medium (M) and large (L) share a very peculiar N-glycosylation pattern, which distinctly regulates their folding, degradation, assembly, intracellular trafficking and antigenic properties. In addition, recent findings indicate important roles of N-linked ol

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Maia, Ivan G., and Adilson Leite. "N-glycosylation in sugarcane." Genetics and Molecular Biology 24, no. 1-4 (2001): 231–34. http://dx.doi.org/10.1590/s1415-47572001000100030.

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The N-linked glycosylation of secretory and membrane proteins is the most complex posttranslational modification known to occur in eukaryotic cells. It has been shown to play critical roles in modulating protein function. Although this important biological process has been extensively studied in mammals, much less is known about this biosynthetic pathway in plants. The enzymes involved in plant N-glycan biosynthesis and processing are still not well defined and the mechanism of their genetic regulation is almost completely unknown. In this paper we describe our first attempt to understand the

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Crunkhorn, Sarah. "Targeting tumour N-glycosylation." Nature Reviews Drug Discovery 21, no. 3 (2022): 180. http://dx.doi.org/10.1038/d41573-022-00028-y.

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Karav, Sercan, J. German, Camille Rouquié, Annabelle Le Parc, and Daniela Barile. "Studying Lactoferrin N-Glycosylation." International Journal of Molecular Sciences 18, no. 4 (2017): 870. http://dx.doi.org/10.3390/ijms18040870.

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Nino Guram, Karkashadze, Rusudan Zurab, Uridia, Nana Prokof, Tserodze, et al. "N-glycosylation of proteins." World Journal of Advanced Research and Reviews 26, no. 1 (2025): 3570–75. https://doi.org/10.30574/wjarr.2025.26.1.1348.

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Maillard reaction includes interaction of reducing sugar with any compound containing free amino group, which is resulted in formation of colored high-molecular compounds [1, 2]. Despite intensive research, a complete mechanism of Maillard reaction is still undefined. Primary product of reaction between sugars and amino acids, N-glycoside right after its formation experiences two types of transformations: 1. hydrolyzation into initial products and 2. rearrangement according to scheme offered by Amadori, which product is 1-amino-1-deoxy-2 ketose [3]. We have studied proteins N-glycosylation mec

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Balieu, Juliette, Jae-Wan Jung, Philippe Chan, George P. Lomonossoff, Patrice Lerouge, and Muriel Bardor. "Investigation of the N-Glycosylation of the SARS-CoV-2 S Protein Contained in VLPs Produced in Nicotiana benthamiana." Molecules 27, no. 16 (2022): 5119. http://dx.doi.org/10.3390/molecules27165119.

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The emergence of the SARS-CoV-2 coronavirus pandemic in China in late 2019 led to the fast development of efficient therapeutics. Of the major structural proteins encoded by the SARS-CoV-2 genome, the SPIKE (S) protein has attracted considerable research interest because of the central role it plays in virus entry into host cells. Therefore, to date, most immunization strategies aim at inducing neutralizing antibodies against the surface viral S protein. The SARS-CoV-2 S protein is heavily glycosylated with 22 predicted N-glycosylation consensus sites as well as numerous mucin-type O-glycosyla

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Pinna, Alessandro, and Christian Marcus Pedersen. "Chemoselectivity in Self-Promoted Glycosylation: N - vs. O -Glycosylation." European Journal of Organic Chemistry 2020, no. 25 (2020): 3914–17. http://dx.doi.org/10.1002/ejoc.202000526.

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Mammadova-Bach, Elmina, Jaak Jaeken, Thomas Gudermann, and Attila Braun. "Platelets and Defective N-Glycosylation." International Journal of Molecular Sciences 21, no. 16 (2020): 5630. http://dx.doi.org/10.3390/ijms21165630.

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N-glycans are covalently linked to an asparagine residue in a simple acceptor sequence of proteins, called a sequon. This modification is important for protein folding, enhancing thermodynamic stability, and decreasing abnormal protein aggregation within the endoplasmic reticulum (ER), for the lifetime and for the subcellular localization of proteins besides other functions. Hypoglycosylation is the hallmark of a group of rare genetic diseases called congenital disorders of glycosylation (CDG). These diseases are due to defects in glycan synthesis, processing, and attachment to proteins and li

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Ryu, Kyoung-Seok, Jie-Oh Lee, Taek Hun Kwon, et al. "The presence of monoglucosylated N196-glycan is important for the structural stability of storage protein, arylphorin." Biochemical Journal 421, no. 1 (2009): 87–96. http://dx.doi.org/10.1042/bj20082170.

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Although N-glycosylation has been known to increase the stability of glycoproteins, it is difficult to assess the structural importance of glycans in the stabilization of glycoproteins. APA (Antheraea pernyi arylphorin) is an insect hexamerin that has two N-glycosylations at Asn196 and Asn344 respectively. The glycosylation of Asn344 is critical for the folding process; however, glycosylation of Asn196 is not. Interestingly, the N196-glycan (glycosylation of Asn196) remains in an immature form (Glc1Man9GlcNAc2). The mutation of Asn196 to glutamine does not change the ecdysone-binding activity

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Dissertations / Theses on the topic "N-glycosylation"

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Karg, Saskia Ruth. "N-glycosylation engineering in tobacco /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17989.

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Harthill, Jean Elizabeth. "N-glycosylation of horseradish peroxidase." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292612.

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Warren, C. E. "N-glycosylation in mice and rats." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315795.

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Hills, Anna E. "Control of monoclonal antibody N-glycosylation." Thesis, University of Kent, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.344101.

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Huffman, Jennifer Elizabeth. "Genetic analysis of protein N-glycosylation." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10038.

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The majority of human proteins are post-translationally modified by covalent addition of one or more complex oligosaccharides (glycans). Alterations in glycosylation processing are associated with numerous diseases and glycans are attracting increasing attention both as disease biomarkers and as targets for novel therapeutic approaches. Using a recently developed high performance liquid chromatography (HPLC) method for high-throughput glycan analysis, genome-wide association studies (GWAS) of 33 directly measured and 13 derived N-glycan features were performed in 3533 individuals from four Eur

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Luz, Johanna Da. "Aspects of N-glycosylation in human IgE /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-130-6.

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Wood, Alison. "N-linked protein glycosylation in Helicobacter species." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/nlinked-protein-glycosylation-in-helicobacter-species(ef97ffdd-aca4-40ff-b52b-7b8ca030bc82).html.

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N-linked protein glycosylation involves the transfer of a glycan onto an Asparagine residue (N) of a polypeptide chain. It is common in Eukaryotes and has recently been observed in Prokaryotes, most notably in Campylobacter jejuni. The C. jejuni N-linked glycosylation system is encoded on a single pgl gene locus that also functions when expressed in Escherichia coli. The key enzyme involved in N-linked protein glycosylation is encoded by the pglB gene and transfers lipid-linked glycan onto N residues of glycoproteins in the periplasm. It is clear from accumulating genome sequence data that pgl

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Murray, Anne Riché. "The functional significance of rhodopsin's N-linked glycosylation." Oklahoma City : [s.n.], 2009.

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Karlsson, Gunilla Birgitta. "Effects of the imino sugar N-butyldeoxynojirimycin on protein N-linked glycosylation." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333246.

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Amatayakul, Supavadee. "Changes in N-glycosylation associated with development and pathology." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253150.

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Books on the topic "N-glycosylation"

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Polyisoprenoid lipids in N-linked protein glycosylation. 2000.

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Morava, Eva, and Mirian C. H. Janssen. Congenital Disorders of Glycosylation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0063.

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Congenital disorders of glycosylation (CDGs) are usually diagnosed during infancy or childhood with severe multisystem disorder and neurologic presentation. With the increasing number of surviving adult patients, recognition of the distinct adult phenotype and awareness of the diagnostic difficulties in adulthood is essential. Patients with O-glycosylation defects or with abnormal dolichol synthesis might present first in adulthood. The majority of cases with adult CDG have a neurologic disease with intellectual disability, ataxia, speech disorder, visual disturbance, and skeletal findings. Ps

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Patterson, Marc C. Congenital Disorders of Glycosylation. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0066.

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Congenital disorders of glycosylation (CDG) comprise a family of multisystem diseases in which N- and O-linked glycosylation and glypiation of a variety of proteins and lipids is deficient. The hypoglycosylation of multiple glycoconjugates impairs normal development of the brain (and other organs), and is associated with both episodic and chronic organ dysfunction. Developmental disorders; seizures; strokelike episodes (and stroke); hearing and visual loss; peripheral neuropathy; coagulopathy; and immune, liver, endocrine, cardiac, and cutaneous manifestations may occur in varying combinations

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4

Popov, Milka. Sugars in space: N-glycosylation mutants of the erythrocyte anion exchanger. 2000.

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5

Zürich, Eidgenössische Technische Hochschule, ed. N-linked glycosylation of the yeast Saccharomyces cerevisiae: The ALG8 locus. 1994.

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6

Partridge, Emily A. Regulation of growth factor receptor signal transduction and cancer progression by N-linked glycosylation and the hexosamine pathway. 2005.

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Book chapters on the topic "N-glycosylation"

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Sekine, Mitsuo. "N-Glycosylation." In Glycoscience: Chemistry and Chemical Biology I–III. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56874-9_21.

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Hirata, Tetsuya, and Yasuhiko Kizuka. "N-Glycosylation." In The Role of Glycosylation in Health and Disease. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-70115-4_1.

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Bardor, Muriel, Gleysin Cabrera, Johannes Stadlmann, et al. "N-Glycosylation of Plant Recombinant Pharmaceuticals." In Recombinant Proteins From Plants. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-407-0_14.

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Krištić, Jasminka, Vlatka Zoldoš, and Gordan Lauc. "Complex Genetics of Protein N-Glycosylation." In Glycoscience: Biology and Medicine. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54836-2_179-1.

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Gu, Jianguo, Qinglei Hang, Tomohiko Fukuda, and Tomoya Isaji. "Integrin α5β1 and Its N-glycosylation." In Glycoscience: Biology and Medicine. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54836-2_53-1.

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Krištić, Jasminka, Vlatka Zoldoš, and Gordan Lauc. "Complex Genetics of Protein N-Glycosylation." In Glycoscience: Biology and Medicine. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54841-6_179.

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Gu, Jianguo, Qinglei Hang, Tomohiko Fukuda, and Tomoya Isaji. "Integrin α5β1 and Its N-Glycosylation." In Glycoscience: Biology and Medicine. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54841-6_53.

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Ghesquière, Bart, Joël Vandekerckhove, and Kris Gevaert. "Mapping protein N-Glycosylation by COFRADIC." In Springer Protocols Handbooks. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-198-7_151.

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Hevér, Helga, Zsuzsanna Darula, and Katalin F. Medzihradszky. "Characterization of Site-Specific N-Glycosylation." In Post-Translational Modification of Proteins. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9055-9_8.

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Veit, Christiane, Ulrike Vavra, and Richard Strasser. "N-Glycosylation and Plant Cell Growth." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1902-4_16.

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Conference papers on the topic "N-glycosylation"

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AEBI, MARKUS. "N-LINKED PROTEIN GLYCOSYLATION." In 23rd International Solvay Conference on Chemistry. WORLD SCIENTIFIC, 2014. http://dx.doi.org/10.1142/9789814603836_0023.

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Sheshukova, E. V., N. M. Ershova, A. A. Antimonova, K. A. Kamarova, and T. V. Komarova. "NICOTIANA BENTHAMIANA XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE NBXTH19 CONTAINS ASN-LINKED GLYCAN AND PARTICIPATES IN RESPONSE TO VIRAL INFECTION." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-282.

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Many cellular proteins involved in plant responses to viral infections are glycoproteins, which are secreted via the endoplasmic reticulum and Golgi apparatus where they undergo glycosylation. Additionally, the presence of N-linked glycans is crucial for their function. In this study, the NbXTH19 protein was examined, and an N-glycosylation site within it was experimentally confirmed.

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Kaufman, Randal J., David G. Bole, and Andrew J. Dorner. "THE INFLUENCE OF N-LINKED GLYCOSYLATION AND BINDING PROTEIN (BiP) ASSOCIATION IN THE SECRETION EFFICIENCY OF COMPLEX GLYCOPROTEINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644016.

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We have studied the role of Binding Protein (BiP) or glucose regulated protein, GRP 78) in the processing and secretion of factor VIII (fVIII), von Willebrand factor (vWF), and tissue plasminogen activator(tPA) expressed in Chinese hamster ovary cell lines.fVIII is a 300 kDa protein which has a heavily glycosylated internal domain containing 20 clustered potential N-linked glycosylation sites.A significant proportion of the expressed fVIII is bound to BiP in the endoplasmic reticulum (ER) in a stable complex andnever secreted. Deletion of the heavily glycosylatedregion results in a lesser degr

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Boiciuc, Chiril, Daniela Blanita, Victoria Hlistun, Dirk Leferber, and Natalia Usurelu. "N-glycosylation of proteins: interference between physiology and pathology." In XIth International Congress of Geneticists and Breeders from the Republic of Moldova. Scientific Association of Geneticists and Breeders of the Republic of Moldova, Institute of Genetics, Physiology and Plant Protection, Moldova State University, 2021. http://dx.doi.org/10.53040/cga11.2021.024.

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Shareef, Sarah J., Mihai Nita-Lazar, and Maria A. Kukuruzinska. "E-cadherin N-glycosylation Modulates the Strength of Adherens Junctions." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13013.

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Metastasis, the spread of cancer cells throughout the body, claims 90% of solid tumor deaths. During metastasis, cancer cells undergo discohesion. An understanding of how to control and strengthen cell adhesion through junction formation could lead to methods for decreasing metastatic tendencies.

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Phillips, Andrew J., Ashley M. Mohr, Mary Anne Phillippi, Justin L. Mott, and Keith R. Johnson. "Abstract 856: N terminal glycosylation regulates FGFR4 cleavage in cholangiocarcinoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-856.

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Phillips, Andrew J., Ashley M. Mohr, Mary Anne Phillippi, Justin L. Mott, and Keith R. Johnson. "Abstract 856: N terminal glycosylation regulates FGFR4 cleavage in cholangiocarcinoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-856.

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Brnakova, Zuzana, Kevin B. Chandler, Slavka Bekesova, et al. "Abstract 5569: N-glycosylation in cultured cells and hepatocellular carcinoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5569.

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Yajit, Noor Liana Mat, Shazilah Kamaruddin, Noor Haza Fazlin Hashim, et al. "Cloning and expression of N-glycosylation-related glucosidase from Glaciozyma antarctica." In THE 2016 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Author(s), 2016. http://dx.doi.org/10.1063/1.4966714.

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Takahashi, Noriko, Joel Cohen-Solal, Annie Galinha, Wolf Herman Fridman, Catherine Sautes-Fridman, and Koichi Kato. "N-GLYCOSYLATION PROFILE OF RECOMBINANT HUMAN SOLUBLE Fc[GAMMA] RECEPTOR III." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.562.

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Reports on the topic "N-glycosylation"

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นิลอุบล, เดชฤทธิ์, อังคณา ตันติธุวานนท์, จิตติมา พิริยะพงศา та ін. โครงการจัดตั้งศูนย์ติดตามวิวัฒนาการและการจัดทำฐานข้อมูลทางพันธุกรรมของเชื้อไวรัสพีอาร์อาร์เอสในฝูงสุกรของประเทศไทย : รายงานการวิจัย. คณะสัตวแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2017. https://doi.org/10.58837/chula.res.2017.71.

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เชื้อไวรัสพีอาร์อาร์เอส เป็นเชื้อที่ก่อให้เกิดความเสียหายแก่อุตสาหกรรมการเลี้ยงสุกรทั่วโลกรวมทั้งประเทศไทย เชื้อไวรัสพีอาร์อาร์เอสแบ่งออกเป็น 2 สายพันธุ์หลัก ได้แก่ สายพันธุ์ยุโรปและสายพันธุ์อเมริกาเหนือ สำหรับประเทศไทยสามารถพบเชื้อไวรัสได้ทั้งสองสายพันธุ์ และยังสามารถแบ่งออกเป็นกลุ่มของเชื้อไวรัสออกเป็นกลุ่มย่อย (คลัสเตอร์) ได้หลายกลุ่มในแต่ละสายพันธุ์อีกด้วย ในการศึกษาวิจัยนี้มีวัตถุประสงค์เพื่อติดตามการเปลี่ยนแปลงทางพันธุกรรมของเชื้อไวรัสพีอาร์อาร์เอสในฝูงสุกรของประเทศไทย โดยมุ่งเน้นไปที่สายพันธุกรรมส่วนยีนโออาร์เอฟ 5 (ORF5) ซึ่งเป็นส่วนที่มีความหลากหลายและมีการเปลี่ยนแปลงทางพันธุกรรมมากที่

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นิลอุบล, เดชฤทธิ์, ธิติมา ไตรพิพัฒน์, ธวัชชัย หุ่นสุวรรณ та กัญจน์ เตมียะเสน. การเปลี่ยนแปลงทางพันธุกรรมส่วนโออาร์เอฟ5ของเชิ้อไวรัสพีอาร์อาร์เอสในฟาร์มสุกรที่ใช้วัคซีนชนิดเชื้อเป็นและผลกระทบต่อศักยภาพการนิวทรัลไลซ์ไวรัส และการผลิตต้นแบบดีเอ็นเอวัคซีนที่มีส่วนประกอบของยีน ORF5 : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2012. https://doi.org/10.58837/chula.res.2012.63.

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การศึกษานี้มีวัตถุประสงค์เพื่อติดตามการเปลี่ยนแปลงพันธุกรรมส่วนโออาร์เอฟห้าของเชื้อไวรัสพีอาร์อาร์เอสหลังการใช้วัคซีนชนิดเชื้อเป็นสายพันธุ์อเมริกาเหนือเมื่อเกิดการระบาดของโรค ดำเนินการวิจัยโดยคัดเลือกฟาร์มที่เกิดการระบาดของโรคพีอาร์อาร์เอสและไม่เคยมีประวัติการใช้วัคซีนพีอาร์อาร์เอสทั้งชนิดเชื้อเป็นและชนิดเชื้อตายในฝูง ทำการฉีดวัคซีนชนิดเชื้อเป็นสายพันธุ์อเมริกาเหนือแบบปูพรมในแม่สุกรและสุกรสาวทดแทนทุกตัวจำนวนสองครั้งห่างกันหนึ่งเดือน ฉีดวัคซีนซ้ำทุกสามเดือนหลังจากฉีดวัคซีนเข็มที่สอง ส่วนลูกสุกรฉีดเป็นโปรแกรมที่อายุประมาณสองสัปดาห์ เก็บตัวอย่างซีรั่มในสุกรสี่กลุ่มๆละห้าตัวอย่างทุกเดือนเป็นเวลาหก

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