Relevant bibliographies by topics / N-nitrososarcosine

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  2. Dissertations / Theses

Academic literature on the topic 'N-nitrososarcosine'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "N-nitrososarcosine"

1

HAMBURG, ANDRES, and ANU HAMBURG. "N-NITROSOPROLINE AND N-NITROSOSARCOSINE IN ESTONIAN FOODSTUFFS." Journal of Food Safety 12, no. 2 (July 1991): 149–59. http://dx.doi.org/10.1111/j.1745-4565.1991.tb00073.x.

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2

Dix, Leslie R., Shirlene M. N. Y. F. Oh, and D. Lyn H. Williams. "Denitrosation of nitrosamines—a quantitative study. Reactions of N-methyl-N-nitrosoaniline, N-nitrosoproline, dimethylnitrosamine and N-nitrososarcosine." J. Chem. Soc., Perkin Trans. 2, no. 8 (1991): 1099–104. http://dx.doi.org/10.1039/p29910001099.

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3

Derave, Wim, Els Vanden Eede, Peter Hespel, Steven G. Carmella, and Stephen S. Hecht. "Oral creatine supplementation in humans does not elevate urinary excretion of the carcinogen N-nitrososarcosine." Nutrition 22, no. 3 (March 2006): 332–33. http://dx.doi.org/10.1016/j.nut.2005.10.004.

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4

Xiang, Yun-Yan, Dong-Yu Wang, Masamitsu Tanaka, Hisaki Igarashi, Takaharu Kamo, Qiong Shen, Haruhiko Sugimura, and Isamu Kino. "Efficient and specific induction of esophageal tumors in rats by precursors of N-nitrososarcosine ethyl ester." Pathology International 45, no. 6 (June 1995): 415–21. http://dx.doi.org/10.1111/j.1440-1827.1995.tb03478.x.

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5

Fiume, Monice M., Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, et al. "Amended Safety Assessment of Fatty Acyl Sarcosines and Sarcosinate Salts as Used in Cosmetics." International Journal of Toxicology 40, no. 2_suppl (July 6, 2021): 117S—133S. http://dx.doi.org/10.1177/10915818211023881.

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The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 acyl sarcosines and 9 sarcosinate salts as used in cosmetics; all of these ingredients are reported to function in cosmetics as hair conditioning agents and most also can function as surfactants—cleansing agents. The ingredients reviewed in this assessment are composed of an amide comprising a fatty acyl residue and sarcosine and are either free acids or simple salts thereof. The Panel relied on relevant new data, including concentration of use, and considered data from the previous Panel report, such as the reaction of sarcosine with oxidizing materials possibly resulting in nitrosation and the formation of N-nitrososarcosine. The Panel concluded that these ingredients are safe as used in cosmetics when formulated to be non-irritating, but these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed.
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6

Wu, Jingcun, William S. Rickert, Andrew Masters, and Peter Joza. "Determination of N-nitrososarcosine in tobacco and smokeless tobacco products using isotope dilution liquid chromatography tandem mass spectrometry." Analytical Methods 4, no. 10 (2012): 3448. http://dx.doi.org/10.1039/c2ay25540e.

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7

Shubin, A. V., E. A. Lesovaya, K. I. Kirsanov, E. E. Antoshina, L. S. Trukhanova, T. G. Gorkova, G. A. Belitsky, M. G. Yakubovskaya, and I. V. Demidyuk. "Re-Examination of the Esophageal Squamous Cell Carcinoma Model in Rats Induced by N-Nitrososarcosine Ethyl Ester Precursors." Bulletin of Experimental Biology and Medicine 164, no. 5 (March 2018): 676–79. http://dx.doi.org/10.1007/s10517-018-4057-2.

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8

Alexandrov, V. A., A. I. Novikov, M. A. Zabezhinsky, V. I. Stolyarov, and A. S. Petrov. "The stimulating effect of acetic acid, alcohol and thermal burn injury on esophagus and forestomach carcinogenesis induced by N-nitrososarcosin ethyl ester in rats." Cancer Letters 47, no. 3 (October 1989): 179–85. http://dx.doi.org/10.1016/0304-3835(89)90088-8.

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9

Werneth, Madeleine, Jutta Pani, Ludwig Hofbauer, Stefan Pummer, Maria-Theres Weber, Georg Pour, Hanspeter Kählig, Bernhard Mayer-Helm, and Herwig Stepan. "Stereospecific Response of E/Z-isomers of N-Nitrososarcosine in LC–ESI–MS/MS." Journal of Chromatographic Science, February 23, 2021. http://dx.doi.org/10.1093/chromsci/bmab013.

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Abstract The carcinogenic compound N-nitrososarcosine (NSAR) is found in foods and tobacco products, and its quantification is of great interest. Although the presence of two stereoisomers, E- and Z-NSAR, is well-known, individual investigation of the isomers has not been reported so far. The present study by liquid chromatography–electrospray ionization–tandem mass spectrometry (LC–ESI–MS/MS) reveals that (i) the mass spectrometric responses of the isomers differ by a factor of approximately two and (ii) the isomer ratio is unstable in freshly prepared standard solutions. As a consequence, NSAR concentrations determined by LC–ESI–MS/MS are biased if those facts are not taken into account. The method described here overcomes the difficulty of stereospecific response by adjusting the isomer ratio and was applied to 100 tobacco products and fully validated for moist and dry snuff reference materials showing expanded measurement uncertainties of ~20% and limits of quantification of ~20 ng/g.
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10

"Final Report on the Safety Assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate." International Journal of Toxicology 20, no. 1_suppl (January 2001): 1–14. http://dx.doi.org/10.1080/10915810152902547x.

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This safety assessment addresses cosmetic ingredients that are N-acyl derivatives of sarcosine and are generally referred to as acyl sarcosines, and those that are salts, known generally as acyl sar-cosinates. Previous assessments have addressed the safety of each of the fatty acids that appear in these acyl sarcosines and sarcosinates (Coconut Acid, Oleic Acid, Lauric Acid, and Myristic Acid). In each case the fatty acid was either safe for use or safe as used in cosmetic formulations. Acyl sarcosines are considered modified fatty acids with greater solubility and increased acidity of the carboxylic acid group compared to the parent fatty acid. They are used in a large number of cosmetic formulations as hair-conditioning agents and surfactant-cleansing agents. In soaps, concentrations are reported to be as high as 12.9%. These ingredients have low oral toxicity in rats. Although cytotoxic to Chinese hamster cells in culture, acyl sarcosines and sarcosinates are not mutagenic in those cells, nor in bacterial cells in culture. Carcinogenicity data were not available. These ingredients are nonirritating and nonsen-sitizing to animal and human skin, although they can enhance the penetration of other ingredients through the skin. For that reason, caution should be exhibited in formulating cosmetic products that contain these ingredients in combination with other ingredients whose safety is based on their lack of absorption or where dermal absorption is a concern (e.g., HC Yellow No. 4, Disperse Yellow 3). Because sarcosine can be nitrosated to form N-nitrososarcosine, a known animal carcinogen, these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed. With the above caveat, and based on the available data, it was concluded that these acyl sarcosines and sarcosinates are safe as used in rinse-off products. They may be safely used in leave-on products at concentrations up to 5%, the highest concentration tested in clinical irritation and sensitization studies. Oleoyl Sarcosine is used as a corrosion inhibitor in some aerosol products, at extremely low concentrations. In this circumstance, the ingredient is not being used as a cosmetic ingredient and this report is not intended to limit that use. Because of the absence of data on inhalation toxicity, however, it was concluded that the available data were not sufficient to support the safety of acyl sarcosines and sarcosinates as cosmetic ingredients in products where they are likely to be inhaled.
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Dissertations / Theses on the topic "N-nitrososarcosine"

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Vavrová, Dominika. "Stanovení netěkavých N-nitrosaminů ve sladu." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-352480.

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The aim of diploma thesis has been development and optimization of method determination of N- nitrososarcosine and N-nitrosoproline in malt by gas chromatography with chemiluminiscence detector. Optimization of extraction method has been performed by response surface method. Quantification has been performed by internal standard method (N-nitrosopipecolic acid, in which matrix effects has been studied. These has been verified in münchen and pilsen malt, therefore matrix-matched calibration has been constructed. The developed method has been aplicated on wheat, münchen and pilsen malt. N- nitrosoproline was detected only in münchen malt and in other cases has been under limit of detection (LOD=4,0 µg/kg). N-nitrososarcosine was in all cases under limit of detection (LOD=3,7 µg/kg). The matrix-matched calibration has been constructed for experimental münchen malt with N-nitrosoproline concentration at 13,2 ± 2,9 µg/kg. Powered by TCPDF (www.tcpdf.org)
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