Academic literature on the topic 'N-stearoylethanolamine'

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Journal articles on the topic "N-stearoylethanolamine"

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Chumak, A., A. Berdyshev, G. Kosyakova, V. Talko, and N. Gula. "Potential use of N-stearoylethanolamine in radiation medicine." Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 20 (2015): 137–46. http://dx.doi.org/10.33145/2304-8336-2015-20-137-146.

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Chumak, A., V. Talko, N. Atamanyuk, et al. "Transgeneration effects of N-stearoylethanolamine in irradiated rats." Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 22 (2017): 270–81. http://dx.doi.org/10.33145/2304-8336-2017-22-270-281.

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Onopchenko, O. V., G. V. Kosiakova, T. M. Goridko, V. M. Klimashevsky, and N. M. Hula. "The effect of N-stearoylethanolamine on liver phospholipid composition." Ukrainian Biochemical Journal 86, no. 1 (2014): 101–10. http://dx.doi.org/10.15407/ubj86.01.101.

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Manko, N., M. Lootsik, V. Antonyuk, et al. "Multifunctional chitosan-based hydrogels: characterization and evaluation of biocompatibility and biodegradability in vitro." Ukrainian Biochemical Journal 96, no. 1 (2024): 80–95. http://dx.doi.org/10.15407/ubj96.01.080.

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Abstract:
Creation of novel remedies efficient in supporting wound healing remains an actual task in pharmacology. Hydrogels showed high efficiency in wound healing and tissue regeneration due to viscosity, elasticity and fluidity that provide them with functional characteristics similar to that in extracellular matrix. The aim of the study was to create chitosan-based hydrogels functionalized with different components (chondroitin-6-sulfate, hyaluronic acid, N-stearoylethanolamine) and to estimate their biocompatibility and biodegradabili­ty in vitro. For the first time, a lipid substance N-stearoylethanolamine (NSE) known as suppressor of pro-inflammatory cytokines expression was used as hydrogel component (1.95 mg/g). FTIR analysis confirmed the complexation of chitosan molecule with hyaluronate, chondroitin-6-sulfate, NSE. MTT-test and Trypan blue exclusion test were used to study hydrogels cytotoxicity towards human cells of different tissue origin. Biodegradability of hydrogels was evaluated using direct hydrogel contact with cells and cell-independent degradation. It was shown that chondroitin-6-sulfate (<2 mg/ml), hyaluronic acid (<2 mg/ml) and NSE (26 µg/ml) did not demonstrate significant toxic effects towards pseudonormal human cells of the MCF10A, HaCat, HEK293 lines and mouse cells of the Balb/3T3 line. The studied hydrogels were stable in saline solution, while in a complete culture medium containing 10% fetal bovine blood serum they underwent degradation in >24 h. The identified biodegradability of the chitosan-based hydrogels is important for the release of noncovalently immobilized NSE into biological medium. Further studies on laboratory animals with experimental wounds are expected to explore the potential of created hydrogels as anti-inflammatory and wound-healing agents. Keywords: biodegradability, chitosan hydrogels, chondroitin-6-sulfate, FTIR analysis, human pseudonormal cells, hyaluronic acid, N-stearoylethanolamine, toxicity
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Horid’ko, T. M., H. V. Kosiakova, and A. G. Berdyshev. "Antistress effects of N-stearoylethanolamine in rats with chronic social stress." Ukrainian Biochemical Journal 89, no. 4 (2017): 68–76. http://dx.doi.org/10.15407/ubj89.04.068.

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Hula, N. M., A. A. Chumak, A. G. Berdyshev, et al. "N-stearoylethanolamine - a new inhibitor of the hepatitis C virus reproduction." Biopolymers and Cell 37, no. 3 (2021): 167–76. http://dx.doi.org/10.7124/bc.000a54.

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Bondarenko, Oleksandr V., N. M. Hula, Mykola Yu Makarchuk, T. M. Horid'ko, and O. A. Kovalenko. "Effects of N-Stearoylethanolamine on the Emotionality and Learning Ability of Rats." International Journal of Physiology and Pathophysiology 6, no. 4 (2015): 277–86. http://dx.doi.org/10.1615/intjphyspathophys.v6.i4.20.

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Zhukov, A. D. "N-stearoylethanolamine effect on the level of 11-hydroxycorticosteroids, cytokines IL-1?,." Ukrainian Biochemical Journal 86, no. 3 (2014): 88–97. http://dx.doi.org/10.15407/ubj86.03.088.

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Bondarenko, OV, NM Hula, MIu Makarchuk, TM Horid'ko, and OA Kovalenko. "Effects of N-stearoylethanolamine on the emotionality and learning ability of rats." Fiziolohichnyĭ zhurnal 60, no. 5 (2014): 52–61. http://dx.doi.org/10.15407/fz60.05.052.

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Onopchenko, Oleksandra V., Galina V. Kosiakova, Murat Oz, Vitaliy M. Klimashevsky, and Nadiya M. Gula. "N-Stearoylethanolamine Restores Pancreas Lipid Composition in Obesity-Induced Insulin Resistant Rats." Lipids 50, no. 1 (2014): 13–21. http://dx.doi.org/10.1007/s11745-014-3960-1.

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Book chapters on the topic "N-stearoylethanolamine"

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Alexander, Steve P. H. "N-Stearoylethanolamine." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.64109-1.

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