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Journal articles on the topic "N-WASP"

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Liu, Chaohong, Shruti Sharma, Heather Miller, et al. "Pivotal roles of both Wiskott-Aldrich syndrome protein (WASP) and N-WASP in the activation and attenuation of the B cell receptor (P1093) (42.1)." Journal of Immunology 188, no. 1_Supplement (2012): 42.1. http://dx.doi.org/10.4049/jimmunol.188.supp.42.1.

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Abstract Lymphocytes express both Wiskott-Aldrich syndrome protein (WASP) and N-WASP. WASP deficiency, the cause of WAS, generates more severe defects in T-cells than B cells, suggesting a strong compensatory role of N-WASP in B cells. Using knockout mouse models, this study shows that WASP knockout (WKO) reduces B cell spreading, B cell receptor (BCR) aggregation, tyrosine phosphorylation, Btk phosphorylation and F-actin accumulation at the B cell surface induced by membrane-associated antigen, and WASP/N-WASP double knockout nearly abolished these activities. However, in B cells with N-WASP
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Adamo, Shelley A. "Feeding suppression in the tobacco hornworm, Manduca sexta: costs and benefits to the parasitic wasp Cotesia congregata." Canadian Journal of Zoology 76, no. 9 (1998): 1634–40. http://dx.doi.org/10.1139/z98-105.

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While the larvae of the parasitic wasp Cotesia congregata developed inside the tobacco hornworm, Manduca sexta, the host's behaviour was similar to that of unparasitized M. sexta. However, once the wasps had exited the host to spin their cocoons, M. sexta stopped feeding. Unparasitized M. sexta ate C. congregata cocoons, which suggests that cessation of feeding by parasitized M. sexta prevented them from consuming the wasps' cocoons. However, suppression of host feeding might be expected to lead to increased host mortality. Host mortality decreased wasp survival. Few cocoons (18%, n = 43) atta
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Clemente, Mateus Aparecido, Karine Munck Vieira, Núbia Ribeiro Campos, Kleber Del-Claro, and Fábio Prezoto. "Social wasp guild (Hymenoptera: Vespidae) visiting flowers in two of the phytophysiognomic formations: Riparian Forest and campos rupestres." Sociobiology 64, no. 2 (2017): 217. http://dx.doi.org/10.13102/sociobiology.v64i2.1364.

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Social wasps are part of the floral visitor guild. In this study we investigated the distribution of flower-visiting wasp species in two phytophysiognomies in the State Park of Ibitipoca, Minas Gerais, Brazil. We inspected flowering plants with visiting wasps along a 1 km transect in riparian forest and another 1 km transect in campos rupestres over the course of one year, for a total sampling effort of 240 hours. We found a total of 103 individuals with 15 species distributed among 7 genera, the most common belonging to the Erythroxylaceae (n = 10) and Asteraceae (n = 10) families. Asteraceae
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Martinez-Quiles, Narcisa, Hsin-Yi Henry Ho, Marc W. Kirschner, Narayanaswamy Ramesh, and Raif S. Geha. "Erk/Src Phosphorylation of Cortactin Acts as a Switch On-Switch Off Mechanism That Controls Its Ability To Activate N-WASP." Molecular and Cellular Biology 24, no. 12 (2004): 5269–80. http://dx.doi.org/10.1128/mcb.24.12.5269-5280.2004.

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ABSTRACT The Arp2/3 complex can be independently activated to initiate actin polymerization by the VCA domain of WASP family members and by the acidic N-terminal and F-actin-binding repeat region of cortactin, which possesses a C-terminal SH3 domain. Cortactin is a target for phosphorylation by Src tyrosine kinases and by serine/threonine kinases that include Erk. Here we demonstrate that cortactin binds N-WASP and WASP via its SH3 domain, induces in vitro N-WASP-mediated actin polymerization, and colocalizes with N-WASP and WASP at sites of active actin polymerization. Erk phosphorylation and
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Park, Haein, та Dianne Cox. "Cdc42 Regulates FcγReceptor-mediated Phagocytosis through the Activation and Phosphorylation of Wiskott-Aldrich Syndrome Protein (WASP) and Neural-WASP". Molecular Biology of the Cell 20, № 21 (2009): 4500–4508. http://dx.doi.org/10.1091/mbc.e09-03-0230.

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Cdc42 is a key regulator of the actin cytoskeleton and activator of Wiskott-Aldrich syndrome protein (WASP). Although several studies have separately demonstrated the requirement for both Cdc42 and WASP in Fcγreceptor (FcγR)-mediated phagocytosis, their precise roles in the signal cascade leading to engulfment are still unclear. Reduction of endogenous Cdc42 expression by using RNA-mediated interference (short hairpin RNA [shRNA]) severely impaired the phagocytic capacity of RAW/LR5 macrophages, due to defects in phagocytic cup formation, actin assembly, and pseudopod extension. Addition of wi
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Liu, Guang-hua, Jian Chen, Zhi-gang Ji, and Li Zhou. "Expression of Neural Wiskott-Aldrich Syndrome Protein in Clear Cell Renal Cell Carcinoma and Its Correlation with Clinicopathological Features." Urologia Internationalis 95, no. 1 (2014): 79–85. http://dx.doi.org/10.1159/000365595.

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Introduction: Neural Wiskott-Aldrich syndrome protein (N-WASP) expression is associated with tumor cell invasion and migration. However, its expression status in clear cell renal cell carcinoma (CCRCC) remains unclear. We examined the level of N-WASP in CCRCC and its association with clinicopathological features characteristic. Materials and Methods: 73 CCRCC patients who underwent radical nephrectomy or partial nephrectomy were enrolled. Immunohistochemical staining for N-WASP was performed on tissue microarrays constructed from tumor and para-tumor tissue obtained from these patients. The di
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Shcherbina, Anna, Hiroaki Miki, Dianne M. Kenney, Fred S. Rosen, Tadaomi Takenawa, and Eileen Remold-O'Donnell. "WASP and N-WASP in human platelets differ in sensitivity to protease calpain." Blood 98, no. 10 (2001): 2988–91. http://dx.doi.org/10.1182/blood.v98.10.2988.

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Abstract Mutations of Wiskott-Aldrich syndrome protein (WASP) underlie the severe thrombocytopenia and immunodeficiency of the Wiskott-Aldrich syndrome. WASP, a specific blood cell protein, and its close homologue, the broadly distributed N-WASP, function in dynamic actin polymerization processes. Here it is demonstrated that N-WASP is expressed along with WASP, albeit at low levels, in human blood cells. The presence of approximately 160 nmol/L rapidly acting N-WASP molecules may explain the normal capacity of WASP-negative patient platelets for early agonist-induced aggregation and filopodia
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Volpi, Stefano, Elettra Santori, Katrina Abernethy, et al. "N-WASP is required for B-cell–mediated autoimmunity in Wiskott-Aldrich syndrome." Blood 127, no. 2 (2016): 216–20. http://dx.doi.org/10.1182/blood-2015-05-643817.

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Key Points Mice lacking both WASP and N-WASP in B lymphocytes have impaired response to T-cell-dependent antigens and defective B-cell activation. Deletion of N-WASP in B cells attenuates autoimmunity in WASP-deficient mice.
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Rohatgi, Rajat, Hsin-yi Henry Ho, and Marc W. Kirschner. "Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate." Journal of Cell Biology 150, no. 6 (2000): 1299–310. http://dx.doi.org/10.1083/jcb.150.6.1299.

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Neuronal Wiskott-Aldrich Syndrome protein (N-WASP) transmits signals from Cdc42 to the nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak activator of Arp2/3 complex, its activity can be enhanced by upstream regulators such as Cdc42 and PI(4,5)P2. We dissected this activation reaction and found that the previously described physical interaction between the NH2-terminal domain and the COOH-terminal effector domain of N-WASP is a regulatory interaction because it can inhibit the actin nucleation activity of the effector domain by occluding the Arp2/3 binding s
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Zhang, Wenwu, Yidi Wu, Liping Du, Dale D. Tang, and Susan J. Gunst. "Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle." American Journal of Physiology-Cell Physiology 288, no. 5 (2005): C1145—C1160. http://dx.doi.org/10.1152/ajpcell.00387.2004.

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Contractile stimulation has been shown to initiate actin polymerization in smooth muscle tissues, and this actin polymerization is required for active tension development. We evaluated whether neuronal Wiskott-Aldrich syndrome protein (N-WASp)-mediated activation of the actin-related proteins 2 and 3 (Arp2/3) complex regulates actin polymerization and tension development initiated by muscarinic stimulation in canine tracheal smooth muscle tissues. In vitro, the COOH-terminal CA domain of N-WASp acts as an inhibitor of N-WASp-mediated actin polymerization; whereas the COOH-terminal VCA domain o
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Dissertations / Theses on the topic "N-WASP"

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Lommel, Silvia. "Conditional inactivation of N-WASP in the mouse analyses of N-WASP function /." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964801922.

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Humphries, A. C. "Regulation of N-WASP-dependent actin polymerisation." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1416391/.

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N-WASP activates the Arp2/3 complex to stimulate actin polymerisation during a number of cellular processes. These include, phagocytosis, endocytosis, and invadopodia and podosome formation. In addition, it is also frequently recruited by pathogens to assist in their actin-dependent spread. During its egress from the cell, vaccinia virus fuses with the plasma membrane and promotes the activation of Src and Abl family kinases. This event leads to phosphorylation of tyrosine 112 and tyrosine 132 of the viral transmembrane protein, A36, triggering a signalling cascade that stimulates actin polyme
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Co, Carl. "N-WASP at the membrane-actin interface." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3251943.

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Benesch, Stefanie. "Analyse der zellulären Funktion von WASP-Scar-Proteinen mit Hilfe N-WASP-defekter Zelllinien." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968832911.

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Khanduja, Nimisha. "Processive Acceleration of Actin Barbed End Assembly by N-WASP." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/54933.

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Actin-based cell motility plays crucial roles throughout the lifetime of an organism. The dynamic rearrangement of the actin cytoskeleton triggers a plethora of cellular processes including cellular migration. Neural Wiskott Aldrich syndrome protein (N-WASP) is involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. N-WASP activated actin polymerization drives extension of invadopodia and podosomes into the basement layer. In addition to activating Arp2/3 complex, N-WASP binds actin filament barbed ends, and both N-WASP and barbed ends are tightly clus
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Edgeworth, Julie Ann. "The role of Cdc42 GTPase effector N-WASP in neurite outgrowth." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407251.

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Morris, Hayley Theresa. "Investigating the role of N-WASP in the development of colorectal cancer." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7174/.

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Colorectal cancer (CRC) is the second most common cancer in Europe, with the second highest mortality rate. Although prognosis is improving, survival rates remain poor for those presenting with the most advanced stages of the disease. There is therefore a need for improved early diagnosis and thus a greater understanding of the early stages of the development of colorectal tumours is desirable. Additionally, as most deaths in colorectal cancer are due to advanced metastatic disease, it is of great interest to explore any potential mechanisms by which metastatic disease can be inhibited. N-WASP
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Watson, Joanna. "Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/268520.

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Cdc42 is a member of the Rho family of small GTPases, which, together with its homologues RhoA and Rac1, controls a multitude of cellular functions via the actin cytoskeleton. Cdc42 exerts its effects on the cytoskeleton via effector proteins of the Wiskott-Aldrich Syndrome (WASP) family and the Transducer of Cdc42-dependent Actin assembly (TOCA) family. The WASP family and their activation by Cdc42 have been thoroughly studied in vitro and are well understood. Conversely, understanding of the TOCA family remains limited by a lack of biochemical, biophysical and structural insight. An investig
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Goeser, Tim [Verfasser]. "Untersuchung adulter Neurogenese in Mäusen mit konditionalen neuronen-spezifisch deletierten N-WASP-Gen / Tim Goeser." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2021. http://d-nb.info/1229691812/34.

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Boafoh, Kofi Kwantwi. "Selectively modifying the interaction of human Tuba SH3-6 domain with listerial InlC and N-WASP." Diss., University of Pretoria, 2020. http://hdl.handle.net/2263/75805.

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Listeriosis is a food-borne disease caused by the gram-positive bacterium Listeria monocytogenes. In extreme cases, listeriosis can lead to sepsis and meningitis. The bacterium uses host actin cytoskeleton for its own motility and to deform the cell membrane and create protrusions into neighbouring cells. Cell-to-cell spread is a hallmark of listeriosis, and it is linked to the virulence protein InlC. InlC binds the sixth SH3 domain of human Tuba (SH3 6), an actin organising protein and in doing so displaces N WASP, the main physiological binding partner of Tuba SH3 6. InlC thereby enables lis
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Books on the topic "N-WASP"

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Staudinger, Ursula M., and Heinz Häfner, eds. Was ist Alter(n)? Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-76711-4.

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Grové, Henriette. In die kamer was 'n kas. Tafelberg, 1989.

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Steve, Propes, ed. What was the first rock 'n' roll record? Faber and Faber, 1992.

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AS IT WAS WRITT(I)N - JOURNAL ENTRIES. JAZZY KITTY GREETINGS MAR, 2015.

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Heidenberger, Felix. Was wirklich geschah--: 40 Jahre Nachrichten-Geschichte(n) im Bayerischen Rundfunk : Biographie eines Nachrichtenjournalisten, 1946-1986. Bayerischer Rundfunk, Historische Kommission, 1992.

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Masloboeva, Ol'ga. Philosophical-anthropological project of Russian organicism and cosmism Russian in the context of the contemporary historical situation. INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1070337.

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This monograph explains the historical necessity of the emergence in the nineteenth century the Russian organicism, and the subsequent birth of his Russian cosmism. On the basis of the age of the principle of the analysis of the history, the idea of which originated in Antiquity, but the most consistent development was in the works, T. N. Granovsky, reveals the connection of the inner logic of a growing world and domestic philosophical thought. Suitable vzaimodeystvie development of the West-European and Russian philosophy is confirmed by the comparative analysis of the evolution of philosophi
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Swan, Walter. Me 'n Henry: A story about two boys growing up on the old family homestead in Cochise County when Arizona was an infant state. Swan Enterprises, 1988.

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The I was a teenage juvenile delinquent rock "n" roll horror beach party movie book: A complete guide to the teen exploitation film, 1954-1969. St. Martin's Press, 1986.

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Toit, Schalk Du. Die ontstaan van die Gemeente Nuwe Kerk op Graaff₋Reinet: 'n kritiese kerkhistoriese₋kerkregtelike evaluering van die gebeure wat aanleiding was tot die kerkskeuring in 1927. Schalk du Toit, 1993.

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Jordaan, Wilhelm, and Ferdinand Deist. Mamma, Was Ek Eers 'n Bobbejaantjie? J L Van Schaik, South Africa, 2004.

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Book chapters on the topic "N-WASP"

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Park, Haein, Athanassios Dovas, and Dianne Cox. "N-WASP." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_605.

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Horstkorte, Rüdiger, Bettina Büttner, Kaya Bork, et al. "N-WASP." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_605.

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Clausen, Torben, José Luis Trejo, Mark P. Mattson, et al. "N-WASP." In Encyclopedia of Exercise Medicine in Health and Disease. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_2775.

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Takenawa, Tadaomi. "From N-WASP to WAVE: Key Molecules for Regulation of Cortical Actin Organization." In Signalling Networks in Cell Shape and Motility. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/047001766x.ch2.

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Kruse, Andreas. "Was ist Alter(n)?" In Lebensphase hohes Alter: Verletzlichkeit und Reife. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-50415-4_2.

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Haifani, Fajar, and Christoph Weidenbach. "Semantic Relevance." In Automated Reasoning. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-10769-6_13.

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AbstractA clause C is syntactically relevant in some clause set N, if it occurs in every refutation of N. A clause C is syntactically semi-relevant, if it occurs in some refutation of N. While syntactic relevance coincides with satisfiability (if C is syntactically relevant then $$N\setminus \{C\}$$ N \ { C } is satisfiable), the semantic counterpart for syntactic semi-relevance was not known so far. Using the new notion of a conflict literal we show that for independent clause sets N a clause C is syntactically semi-relevant in the clause set N if and only if it adds to the number of conflict literals in N. A clause set is independent, if no clause out of the clause set is the consequence of different clauses from the clause set.Furthermore, we relate the notion of relevance to that of a minimally unsatisfiable subset (MUS) of some independent clause set N. In propositional logic, a clause C is relevant if it occurs in all MUSes of some clause set N and semi-relevant if it occurs in some MUS. For first-order logic the characterization needs to be refined with respect to ground instances of N and C.
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Rusinamhodzi, Leonard, James Njeru, John E. Sariah, Rama Ngatoluwa, and Phlorentin P. Lagwen. "Tillage effect on agronomic efficiency of nitrogen under rainfed conditions of Tanzania." In Conservation agriculture in Africa: climate smart agricultural development. CABI, 2022. http://dx.doi.org/10.1079/9781789245745.0014.

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Abstract Nitrogen (N) deficiency is a common feature in soils managed by smallholder farmers in Africa. Crop residue retention, in combination with no-till (NT), may be a pathway to improve agronomic use efficiency of applied N for small-scale farmers under the predominant rainfed conditions. This chapter reports on the results of a study carried out over two cropping seasons in the long rains of 2014 and 2015 on two sites: (i) on-farm (Mandela); and (ii) a research station (SARI) in eastern Tanzania. The experiment consisted of two tillage systems, conventional tillage (CT) and Conservation Agriculture (CA), with a minimum of 2.5 t ha-1 crop residue cover maintained in the plots during the experiment. CT consisted of soil inversion through tillage and removal of crop residues. In the on-farm experiment, maize was grown in plots with four rates of N application: 0, 27, 54 and 108 kg N ha<sup>-1</sup>. In the on-station trial, five rates were used: 0, 20, 40, 60 and 100 kg N ha-1. Maize yield and agronomic efficiency (AE) of N were used to assess and compare the productivity of the tested treatments. The results showed that tillage, soil type and rate of N application influenced crop productivity. In the clay soils, the differences between tillage practices were small. Under CT, AE ranged between 21.6 and 53.9 kg/kg N, and it was 20.4-60.6 kg/kg N under CA. The lowest fertilizer application rate of 27 kg ha<sup>-1</sup> often had the largest AE across the soil types and tillage practices. In the on-station trials at SARI, the largest AE of 24.6 kg/kg N was recorded under CA with 40 kg N ha-1. As in the on-farm trials, the highest N application rate on-station did not lead to the largest AE. In the CT, AE ranged between 11.5 and 16.8 kg/kg N compared with a range of 15.1 to 24.6 kg/kg N for the CA treatment. Overall, crop residue retention, in combination with NT, is important to improve soil moisture and use efficiency of applied nutrients. Additionally, the initial soil fertility status is also important in determining the magnitude of short-term crop response to applied nutrients. Innovative pathways are needed to achieve the multiple objectives played by maize crop residues for results reported here to be sustainable. However, efficiency of nutrient use needs to be assessed, together with returns on investments, as small yields may mean high nutrient use efficiency but not necessarily significant increased returns at the farm level.
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Çakar, Kadir, and İsmail Uzut. "Exploring birdwatchers' experiences through an analysis of online narratives." In Managing visitor experiences in nature-based tourism. CABI, 2021. http://dx.doi.org/10.1079/9781789245714.0009a.

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Abstract This chapter explores the concept of visitor experiences of birdwatchers as a nature-based tourism activity, focusing on the types of visitor experiences (e.g. restorative, cognitive, emotional, transformative, etc.) that are offered within birdwatching tourism. Online narratives of travellers that addressed visitor experiences were included in this study. The traveller reviews address four different destinations, namely The Gambia (n=375), Sayulita, Mexico (n=20), Malaysia (n=119) and Melbourne, Australia (n=148). The focus of the analysis was on the relationship between behaviour patterns of tourists and their post-trip experiences. Management implications deriving from the study results related to birdwatching experiences are presented and discussed.
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Çakar, Kadir, and İsmail Uzut. "Exploring birdwatchers' experiences through an analysis of online narratives." In Managing visitor experiences in nature-based tourism. CABI, 2021. http://dx.doi.org/10.1079/9781789245714.0109.

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Abstract This chapter explores the concept of visitor experiences of birdwatchers as a nature-based tourism activity, focusing on the types of visitor experiences (e.g. restorative, cognitive, emotional, transformative, etc.) that are offered within birdwatching tourism. Online narratives of travellers that addressed visitor experiences were included in this study. The traveller reviews address four different destinations, namely The Gambia (n=375), Sayulita, Mexico (n=20), Malaysia (n=119) and Melbourne, Australia (n=148). The focus of the analysis was on the relationship between behaviour patterns of tourists and their post-trip experiences. Management implications deriving from the study results related to birdwatching experiences are presented and discussed.
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Roos, Vera, Anél du Plessis, and Jaco Hoffman. "Municipal Service Delivery to Older Persons: Contextualizing Opportunities for ICT Interventions." In Age-Inclusive ICT Innovation for Service Delivery in South Africa. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94606-7_2.

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AbstractThis chapter has a threefold aim: (1) to contextualize older persons’ inclusivity at municipal level as outlined in Goal 11 of the United Nations Sustainable Development Goals (SDGs) and international, African regional and South African law and policy frameworks; (2) to obtain an assessment of service delivery by local government, and (3) to reflect on gaps in service delivery and offer suggestions. Stratified sampling was used and information obtained through semi-structured interviews, emailed responses and focus groups from representatives (n = 17) on three local government levels, NGO representatives (n = 5), and officials from the South African Local Government Association (SALGA) and the Department of Social Development (n = 26). A sample of older persons (n = 302) from a rural area and two large towns in North West and Gauteng provinces completed questionnaires and participated in semi-structured interviews (n = 14) and focus groups (n = 22). Findings indicated compromised service delivery related to local government officials’ systemic, managerial, and capacity challenges. Municipal services were either non-existent or age-inappropriate. Local government’s unresponsiveness leaves older people at risk—particularly those who lack social networks. We present suggestions to address the disconnect between the intent of laws and policies for inclusivity and municipal service delivery, and the service delivery experiences of older persons.
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Conference papers on the topic "N-WASP"

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Lee, Jae Kyung, Amotz Ziv Av, Cunli Xiang, et al. "Abstract LB-268: RTVP-1 regulates glioma cell migration and podosome formation via interaction with N-WASP." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-lb-268.

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Chaudhary, Pankaj, Marilyne Kpetemey, Timothy Van Treuren, and Jamboor K. Vishwanatha. "Abstract 5812: MIEN1 promotes breast cancer cell migration and invasion by regulating cytoskeletal dynamics via focal adhesion kinase and N-WASP." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5812.

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Zhang, Wenwu, Rong Zhao, and Susan J. Gunst. "RhoA Regulates N-WASp And Arp2/3 Mediated Actin Polymerization And Airway Smooth Muscle (ASM) Contraction By Regulating The Activation Of Cdc42 And P21-activated Kinase (PAK)." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5303.

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Mandelsloh, F. von, A. Begerow, D. Morciniec, and U. Gaidys. "„(...) naja, was ich gerne hätte, wäre so n Abendaustausch, ne.“ – Interviewergebnisse der Evaluation des Hamburger Quartiersprojektes AGQua." In „Neue Ideen für mehr Gesundheit“. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1694505.

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Gomes Filho, José Euderaldo Costa, Ariane Silva da Rocha, Gisele Aparecida Fernandes, Rossana Verónica Mendoza López, and Maria Paula Curado. "PRE- AND POSTMENOPAUSAL BREAST CANCER IN COMPARISON OF CLINICAL AND PATHOLOGICAL FEATURES, HISTOLOGY, BIOMARKERS, AND MOLECULAR CLASSIFICATION." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2043.

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The aim of this study was to analyze the clinical and pathological evolution, morphology, hormonal biomarkers (estrogen, progesterone, HER2, and Ki-67), and molecular classification in pre- and postmenopausal patients (age ≤50 years and &gt;50 years). This is a cross-sectional study of 705 female patients with breast cancer. A total of 55.9% (n=394) of patients were above 50 years, whereas 44.1% (n=311) were aged 50 years or below. The laterality of the tumor was similar in both age groups on the right side, 50.2% (n=156) for premenopausal and 53.3 (n=210) for postmenopausal (p=0.226), as was
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Gomes Filho, José Euderaldo Costa, Ariane Silva da Rocha, Gisele Aparecida Fernandes, Rossana Verónica Mendoza López, and Maria Paula Curado. "SOCIODEMOGRAPHIC AND LIFESTYLE ASPECTS VERSUS ACCESS TO TREATMENT FOR PATIENTS WITH BREAST CANCER AT A CANCER CENTER IN SÃO PAULO." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2041.

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Sociodemographic and lifestyle aspects versus access to breast cancer treatment — Single Health System (SHS) and Supplementary Health — were evaluated in a prospective cohort of patients with breast cancer. This is a cross-sectional study with 705 patients. As compared with sociodemographic characteristics, 56.5% (n=398) of the patients were seen through Supplementary Health, and for both SHS and Supplementary Health patients, there is a higher frequency of women aged above 50 years, with 62.2% (n=191) and 51% (n=203) (p=0.002); married, 48.2% (n=148) and 66.6% (n=265) (p &lt;0.001); white, 69
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Gomes Filho, José Euderaldo Costa, Ariane Silva da Rocha, Gisele Aparecida Fernandes, Rossana Verónica Mendoza López, and Maria Paula Curado. "SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS IN PRE- AND POSTMENOPAUSAL PATIENTS WITH BREAST CANCER." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2103.

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To analyze pre- and postmenopausal patients with breast cancer with regard to sociodemographic factors. This is a crosssectional study with 705 patients with breast cancer. Patients aged 50 years and older accounted for 55.9% (n=394), whereas those aged 50 years or younger accounted for 44.1% (n=311). For both pre- and postmenopausal patients, there is greater proportional access through the Unified Health System (SUS), 62.7% (n=195) and 51.5% (n=203) (p=0.002); married, 65.9% (n=205) and 52.8% (n=208) (p&lt;0.001); white ethnicity, 75.9% (n=236) and 77 (n=302) (p=0.623); and undergraduate lev
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Li, Calvin Hong. "Experimental Study of Nanoadditives for Biofuel Combustion Improvement." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62357.

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An experimental investigation of the combustion behavior of nano-aluminum (n-Al) and nano-aluminum oxide (n-Al2O3) particles, stably suspended in biofuel (ethanol) as a secondary energy carrier was conducted. The heat of combustion (HoC) was studied using a modified static bomb calorimeter system. Combustion element composition and surface morphology were evaluated using a SEM/EDS system. N-Al and n-Al2O3 particles of 50 nm and 36 nm diameters, respectively, were utilized in this investigation. Combustion experiments were performed with volume fractions of 1%, 3%, 5%, 7%, and 10% for n-Al, and
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Gomes Filho, José Euderaldo Costa, Ariane Silva da Rocha, Gisele Aparecida Fernandes, Rossana Verónica Mendoza López, and Maria Paula Curado. "CLINICAL AND PATHOLOGICAL CHARACTERISTICS AND MOLECULAR SUBTYPES IN A PROSPECTIVE COHORT OF PATIENTS WITH BREAST CANCER ACCORDING TO ACCESS TO TREATMENT: SUPPLEMENTARY HEALTH CARE VERSUS UNIFIED HEALTH SYSTEM." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2042.

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The aim of this study was to describe the clinical and pathological characteristics and molecular subtypes in a prospective cohort of patients with breast cancer based on access to treatment — Supplementary Health Care versus Unified Health System (UHS). This is a cross-sectional study aligned to a prospective cohort developed at Hospital AC Camargo Cancer Center with 705 female patients, aged between 18 and 93 years and diagnosed with breast cancer. They had access to treatment by Supplementary Health (56.5%, n=398). Tumor topography for both UHS and Supplementary Health group include higher
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Dagaut, Philippe. "Kinetics of Kerosene Combustion Over Extended Conditions: Experimental and Modeling." In ASME Turbo Expo 2006: Power for Land, Sea, and Air. ASMEDC, 2006. http://dx.doi.org/10.1115/gt2006-90015.

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The oxidation of kerosene (Jet-A1) and that of surrogate mixtures have been studied experimentally in a jet-stirred reactor at 1 to 40 atm and constant residence time, over the high temperature range 800–1300 K, and for variable equivalence ratio 0.5&amp;lt;φ&amp;lt;2). Concentration profiles of the reactants, stable intermediates, and final products have been obtained by probe sampling followed by on-line and off-line GC analyses. The oxidation of kerosene in these conditions was modeled using a detailed kinetic reaction mechanism (209 species and 1673 reactions, most of them reversible). In
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Reports on the topic "N-WASP"

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Pichot, Christina S. Recruitment & Regulation of N-Wasp by F-Bar Family Member CIP4 in Invasive Breast Cancer Cells. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada517228.

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Werren, John H., Einat Zchori-Fein, and Moshe Coll. Parthenogenesis-Inducing Microorganisms in Parasitic Hymenoptera: Their Mode of Action and Utilization for Improvement of Biological Control Agents. United States Department of Agriculture, 1996. http://dx.doi.org/10.32747/1996.7573080.bard.

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Wolbachia are intracellular bacteria known to cause reproductive and sex ratio disorders in many insects. In various parasitic Hymenoptera, Wolbachia induce thelytokous reproduction. The overall goal of this research was the improvement of biological control agents by reversion of their mode of reproduction. This was attempted from two directions: 1) studying the effect of naturally occurring Wolbachia on the thelytokous species Muscidifuraxuniraptor and 2) trying to transmit thelytoky-inducing Wolbachia to Nasoniavitripennis. In M. uniraptor, gamete duplication was found to be the mode of dip
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Cohen, Yafit, Carl Rosen, Victor Alchanatis, David Mulla, Bruria Heuer, and Zion Dar. Fusion of Hyper-Spectral and Thermal Images for Evaluating Nitrogen and Water Status in Potato Fields for Variable Rate Application. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7594385.bard.

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Potato yield and quality are highly dependent on an adequate supply of nitrogen and water. Opportunities exist to use airborne hyperspectral (HS) remote sensing for the detection of spatial variation in N status of the crop to allow more targeted N applications. Thermal remote sensing has the potential to identify spatial variations in crop water status to allow better irrigation management and eventually precision irrigation. The overall objective of this study was to examine the ability of HS imagery in the visible and near infrared spectrum (VIS-NIR) and thermal imagery to distinguish betwe
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I. A. Parshikov, Igor A. OXIDATION OF GERANYL-N-PHENYLCARBAMATE BY FUNGUS BEAUVERIA BASSIANA WITH AIM TO OBTANING OF NEW ANTI-CANCER DRUGS. Intellectual Archive, 2020. http://dx.doi.org/10.32370/iaj.2427.

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The microbial oxidation of geranyl-N-phenylcarbamate by fungus Beauveria bassiana was investigated. Oxidation of the C3 – C4 double bond of the parent molecule leads to regioselective formation of O-3,4-epoxyheranyl-N-phenylcarbamate in 30 % yield
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Wackett, Lawrence, Raphi Mandelbaum, and Michael Sadowsky. Bacterial Mineralization of Atrazine as a Model for Herbicide Biodegradation: Molecular and Applied Aspects. United States Department of Agriculture, 1999. http://dx.doi.org/10.32747/1999.7695835.bard.

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Atrazine is a broadly used herbicide in agriculture and it was used here as a model to study the biodegradation of herbicides. The bacterium Pseudomonas sp. ADP metabolizes atrazine to carbon dioxide and ammonia and chloride. The genes encoding atrazine catabolism to cyanuric acid were cloned and expressed in Escherichia coli. The genes were designated atzA, atzB and atzC. Each gene was sequenced. The enzyme activities were characterized. AtzA is atrazine chlorohydrolase which takes atrazine to hydroxyatrizine. AtzB is hydroxyatrazine N-ethylaminohydrolase which produces N-isopropylammelide an
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McDonagh, Marian S., Jesse Wagner, Azrah Y. Ahmed, et al. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer250.

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Objectives. To evaluate the evidence on benefits and harms of cannabinoids and similar plant-based compounds to treat chronic pain. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases, reference lists of included studies, submissions received after Federal Register request were searched to July 2021. Review methods. Using dual review, we screened search results for randomized controlled trials (RCTs) and observational studies of patients with chronic pain evaluating cannabis, kratom, and similar compounds with any comparison group and at least 1 month
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Chou, Roger, Jesse Wagner, Azrah Y. Ahmed, et al. Living Systematic Review on Cannabis and Other Plant-Based Treatments for iii Chronic Pain: 2022 Update. Agency for Healthcare Research and Quality (AHRQ), 2022. http://dx.doi.org/10.23970/ahrqepccer250update2022.

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Objectives. To update the evidence on benefits and harms of cannabinoids and similar plant-based compounds to treat chronic pain using a living systematic review approach. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases; reference lists of included studies; and submissions received after Federal Register request were searched to April 4, 2022. Review methods. Using dual review, we screened search results for randomized controlled trials (RCTs) and observational studies of patients with chronic pain evaluating cannabis, kratom, and similar compounds
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Bar-Tal, Asher, Paul R. Bloom, Pinchas Fine, et al. Effects of soil properties and organic residues management on C sequestration and N losses. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7587729.bard.

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Objectives - The overall objective of this proposal was to explore the effects of soil properties and management practices on C sequestration in soils and off-site losses of N.The specific objectives were: 1. to investigate and to quantify the effects of soil properties on C transformations that follow OW decomposition, C losses by gaseous emission, and its sequestration by organic and mineral components of the soil; 2. to investigate and to quantify the effects of soil properties on organic N mineralization and transformations in soil, its losses by leaching and gaseous emission; 3. to invest
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Loebenstein, Gad, William Dawson, and Abed Gera. Association of the IVR Gene with Virus Localization and Resistance. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604922.bard.

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We have reported that localization of TMV in tobacco cultivars with the N gene, is associated with a 23 K protein (IVR) that inhibited replication of several plant viruses. This protein was also found in induced resistant tissue of Nicotiana glutinosa x Nicotiana debneyi. During the present grant we found that TMV production is enhanced in protoplasts and plants of local lesion responding tobacco cultivars exposed to 35oC, parallel to an almost complete suppression of the production of IVR. We also found that IVR is associated with resistance mechanisms in pepper cultivars. We succeeded to clo
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Woods, Rachel, Alison Zhong, and Madelyn Vincent. Factors Associated with Influenza & Tdap Vaccine Uptake in Pregnant Patients at the UT Family Medicine Clinic in Memphis. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/com.lsp.2020.0003.

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INTRODUCTION: Given the increased risk for infections among pregnant patients and newborns, vaccination against influenza (&gt;50,000,000 annual US cases affecting all ages) and pertussis (&gt;15,000 annual US cases disproportionately affecting newborns) are recommended among pregnant patients in order to protect them and their babies via passive immunity to cover a newborn’s window of vaccine ineligibility. Though flu and Tdap vaccination rates among pregnant patients have been trending upwards nationally, there is still room for improvement to achieve optimal rates. OBJECTIVES: The primary o
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