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Journal articles on the topic 'Nano-Carrier System'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Hamsici, Seren, Melis Sardan Ekiz, Goksu Cinar Ciftci, Ayse B. Tekinay, and Mustafa O. Guler. "Gemcitabine Integrated Nano-Prodrug Carrier System." Bioconjugate Chemistry 28, no. 5 (2017): 1491–98. http://dx.doi.org/10.1021/acs.bioconjchem.7b00155.

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Hidayah, Rohmawati, Widji Soeratri, and Noorma Rosita. "Nano Carrier as a Cosmetic Delivery System." Sun International Journal of Engineering and Basic Sciences 01, no. 03 (2018): 45–48. http://dx.doi.org/10.30558/ijebs.20180103002.

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3

Gupta, Ajay Kumar, Diptee Gupta, and Vedant Gupta. "Aquasomes: A Self-Assembled Nano-Particulate Carrier System." International Journal of Current Research and Review 13, no. 04 (2021): 44–52. http://dx.doi.org/10.31782/ijcrr.2021.13427.

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M Shabbir, M. Sohil, Shaikh Imran Kalam, Dr G. J. Khan, Shaikh Md Moiz, and Shaikh Aman. "Targeted Drug Delivery System." International Journal of Research in Pharmacy and Allied Science 04, no. 01 (2025): 01–19. https://doi.org/10.71431/ijrpas.2025.4101.

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Paul Ehrlich's idea of a "magic bullet" has evolved into Nano medicine. In order to circumvent the particular harmful effect of traditional drug distribution, targeted drug delivery reduces the amount of drug needed for therapeutic efficacy by delivering the drug moiety directly to the specified body location (organ, cellular, and subcellular level of specific tissue). The idea of a "magic bullet" was developed to achieve this aim, and after more than a century of research, scientists created a number of devices that are nanometers in size, which is known as "Nano medicine." Among the carrier

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D, Prasanthi, Sagarla Usharani, and Naredla Bhashpitha. "Pharmaceutical Carrier’s for Topical Drug Delivery System." Asian Journal of Pharmaceutical Research and Development 11, no. 4 (2023): 115–22. http://dx.doi.org/10.22270/ajprd.v11i4.1294.

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Beginning with a revenue breakdown of this specific market, this study seeks to describe the intricate world of drug carriers. A quick introduction of various different types of traditional and cutting-edge drug carrier systems is provided in the section that follows.Avariety of topical active substances, such as sunscreen ingredients, corticosteroids, and antibacterial, antifungal, and antiviral agents, can be delivered via foam technology. Ointments are semisolids used for external skin or mucous membrane treatment. Less than 20% of them often contain water and volatiles. Targeted medication

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Joy, Chanchal, Smitha K. Nair, K. Krishna Kumar, and B. Dineshkumar. "Niosomes as Nano-carrier Based Targeted Drug Delivery System." Journal of Drug Delivery and Therapeutics 11, no. 4-S (2021): 166–70. http://dx.doi.org/10.22270/jddt.v11i4-s.4907.

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Niosomes are considered as novel nano-carrier in the drug delivery systems. These are much more stable than other nano-carriers like liposomes and nanoparticles. It is an example for targeted and control release of medication. The drug is entrapped into lipid core so that it prevents the drug from leaching. Here the drug will be targeted only to the desired cell/tissue and not to the non-targeted cells. By giving this formulation we can thereby reduce the dose of the drug and toxicity. This review article mainly emphasizes on the potential applications of niosomes in targeted drug delivery sys

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Rajalakshmi, G., C. K. Dhanapal, and R. Sundhararajan. "An Insight to Nanostructured Lipid Carrier System." Journal of Drug Delivery and Therapeutics 10, no. 6-s (2020): 173–82. http://dx.doi.org/10.22270/jddt.v10i6-s.4589.

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In pharmaceutical field, many drugs are being invented to combat the existing new diseases. The winds of change in the drug scenario are blowing forcefully worldwide. The emergence of new technologies provides an unique opportunities to exploit novel approaches in drug delivery. A shift from conventional drug delivery to novel drug delivery is noticed as shift from conventional drug delivery suffers from various drawbacks, But these new mighty compounds in drug therapy solely are not sufficient to meet the today’s need. There is an urgent need for the smart technology, as the drugs available s

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Komathy J, Sangeetha S, Gayathri H, and Damodharan N. "Transferosomes- Nano Vesicular Carrier for Skin Cancer." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2799–806. http://dx.doi.org/10.26452/ijrps.v11ispl4.4557.

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Transferosomes creating a new development in delivering a drug through skin. In oral, parenteral drug delivery system shows poor patient compliance are the major complication in clinical practice. Well, Transdermal route has obtained an appreciable interest in pharmaceutical research. Transferosomes consist of both hydrophobic, hydrophilic moieties together results, the drug molecule with wide range of solubility and possess flexible Nano-vesicles formulation comprise of lipid and surfactant. It offers a versatile delivery concept for improving stability, potential for active compound. Major a

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Eldose, Anmol, Parmar Twinkle, Shah Honey, Zala Twinkle, Hitesh Jain, and Upadhyay Umesh. "Nanosponge: A Novel Nano Drug Carrier." Journal of Advance Research in Pharmacy & Biological Science (ISSN: 2208-2360) 1, no. 7 (2015): 01–07. http://dx.doi.org/10.53555/nnpbs.v1i7.565.

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Nanotechnology, a multi-disciplinary science has received considerable attention in the recent times in the discovery of new chemical entities, diagnosis and treatment of several diseases. Nano-medicine has developed many drug delivering systems like nanoparticles, nano-emulsions, nano-suspensions, nanosponges etc., to overcome the problems of bioavailability out of which nanosponge is an advanced drug delivery system which offers diverse advantages than the other available systems. Targeted drug delivery to specific sites is the significant problem which is being faced by the researchers. The

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10

Mary DCruz, Cleona Elizabeth, Prashant Jivaji Bhide, Lalit Kumar, and Rupesh Kalidas Shirodkar. "Novel nano spanlastic carrier system for buccal delivery of lacidipine." Journal of Drug Delivery Science and Technology 68 (February 2022): 103061. http://dx.doi.org/10.1016/j.jddst.2021.103061.

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Prasad, Pramod. "A Beacon for Gynaecological Cancers Patients: pH-Sensitive Nano medicine." Obstetrics Gynecology and Reproductive Sciences 4, no. 1 (2020): 01–10. http://dx.doi.org/10.31579/2578-8965/035.

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Emergence of various Nano scale drug carrier platforms as Drug Delivery Systems (DDS) has revolutionized the field of medicine. Nonetheless, the side-effects due to non-specific distribution of anticancer therapeutics in normal, healthy tissues remain to be a prime pitfall in curing cancers. Therefore, to achieve a better therapeutic efficacy, the use of a target-specific delivery, combined with a stimuli-responsive Nano carrier system, particularly pH-sensitive Nano systems offer an attractive strategy. Targeted drug delivery through pH-sensitive Nano systems offer the potential to enhance th

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K., Arya G., Anjaly A. Kumar, Archana J. Nair, Jeni Raju, and Sreeja C. Nair. "NANODISCS: A NEW EPOCH IN THE STUDY OF MEMBRANE PROTEINS AND AS AN EMERGING DRUG DELIVERY SYSTEM." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 1. http://dx.doi.org/10.22159/ijap.2019v11i1.28398.

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Nano discs recently evolved as a novel tool for studying the membrane associated proteins and serve as an effective drug delivery system. Nano discs constitute disc shaped nano particles and can be defined as a membrane system which is synthetic in nature and aids in the study of membrane proteins. It is mainly made of phospholipid bilayer and the water repelling edge is isolated by amphipathic proteins called membrane scaffolding proteins [MSP]. Micelles present in the nano disc mimics the property of the biological membrane proteins. It is a powerful technology that competently delivers the

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Tong, Guoquan, Zhuangnian Fang, Gang Huang, et al. "Gadolinium/DOTA functionalized poly(ethylene glycol)-block-poly(acrylamide-co-acrylonitrile) micelles with synergistically enhanced cellular uptake for cancer theranostics." RSC Advances 6, no. 56 (2016): 50534–42. http://dx.doi.org/10.1039/c6ra04038a.

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14

Kim, Jung Suk, Fakhar ud Din, Hyuk Jun Cho, et al. "Impact of carrier hydrophilicity on solid self nano-emulsifying drug delivery system and self nano-emulsifying granule system." International Journal of Pharmaceutics 648 (December 2023): 123578. http://dx.doi.org/10.1016/j.ijpharm.2023.123578.

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Praveen Tahilani and D P Chatterjee. "Advancements in Protein based Nano Particulate system for treatment of Pulmonary Infections- A Review." Asian Pacific Journal of Nursing and Health Sciences 4, no. 1 (2021): 22–34. http://dx.doi.org/10.46811/apjnh/4.1.4.

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In addition to the so-called small molecule drugs, proteins and peptides are of increasing interest forpharmacotherapy, due to several advantageous properties. In general, those compounds are administered parenterally. However, non-invasive routes of administration represent a great part of research. Amongst others is the pulmonary application of proteins and peptides for local delivery in the case of pulmonary diseases, such as idiopathic pulmonary fibrosis, where the alveolar epithelium is affected. To ensure an intracellular delivery, nano particles in a size range of 150 nm will be prepare

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Yıldırım, Özge Çağlar, Mehmet Enes Arslan, Sena Öner, et al. "Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer’s Disease Treatment." International Journal of Molecular Sciences 23, no. 15 (2022): 8249. http://dx.doi.org/10.3390/ijms23158249.

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The search for an innovative and effective drug delivery system that can carry and release targeted drugs with enhanced activity to treat Alzheimer’s disease has received much attention in the last decade. In this study, we first designed a boron-based drug delivery system for effective treatment of AD by integrating the folic acid (FA) functional group into hexagonal boron nitride (hBN) nanoparticles (NPs) through an esterification reaction. The hBN-FA drug carrier system was assembled with a new drug candidate and a novel boron-based hybrid containing an antioxidant as BLA, to constitute a s

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17

Jain, Dharmendra, Nagesh Dewangan, Dhalendra Kothale,, and Utsav Verma. "Nanoemulsion as a Nano Carrier System in Drug Delivery: A Review." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 2 (2021): 5353–63. http://dx.doi.org/10.37285/ijpsn.2021.14.2.1.

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Nanoemulsions are colloidal dispersions having smaller globule size that ranges from 20-600 nm. They are clear transparent and kinetically stable formulations commonly available in the form of creams, shampoos, gels, sprays and aerosols. Nanoemulsions are nano carrier drug delivery system for the protection of drugs from severe environmental conditions like pH, oxidation and hydrolysis. Nanoemulsions are normally contains oil phase, aqueous phase, surfactants and co-surfactants. Different methods are employed for the preparations of nanoemulsions are high pressure homogenization, microfluidiza

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18

Albasri, Omar Waleed Abduljaleel, Palanirajan Vijayaraj Kumar, and Mogana Sundari Rajagopal. "Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin." Molecules 28, no. 4 (2023): 1833. http://dx.doi.org/10.3390/molecules28041833.

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The oral delivery system is very important and plays a significant role in increasing the solubility of drugs, which eventually will increase their absorption by the digestive system and enhance the drug bioactivity. This study was conducted to synthesize a novel curcumin nano lipid carrier (NLC) and use it as a drug carrier with the help of computational molecular docking to investigate its solubility in different solid and liquid lipids to choose the optimum lipids candidate for the NLCs formulation and avoid the ordinary methods that consume more time, materials, cost, and efforts during la

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19

Negi, Lalit Mohan, Meenakshi Chauhan, and Atul Kumar Garg. "Nano-appended transdermal gel of Tenoxicam via ultradeformable drug carrier system." Journal of Experimental Nanoscience 8, no. 5 (2013): 657–69. http://dx.doi.org/10.1080/17458080.2011.597441.

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20

Palesh S Rajkondawar and Amit B Patil. "Nano-sponges: A Novel Carrier for Delivery of Chemo-therapeutic Drugs." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 1040–44. http://dx.doi.org/10.26452/ijrps.v11i1.1933.

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Nano-sponges belong to the category of hyper-cross linked polymer which is based on the colloidal structure. Nano-sized carriers are developed recently and are being used to deliver poorly water soluble drug by modifying the pharmaco-kinetic parameter and provide enhanced prolonged release. As a new class of chemo-therapeutic agents is being developed, formulation is getting difficult to issues such as poor solubility, low loading capacity and less entrapment of the drug in the drug delivery system. Nano-sponges have shown to deliver the most complex and challenging Chemo therapeutic drugs due

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Segneanu, Adina-Elena, Catalin Nicolae Marin, Ioan Ovidiu-Florin Ghirlea, Catalin Vladut Ionut Feier, Cornelia Muntean, and Ioan Grozescu. "Artemisia annua Growing Wild in Romania—A Metabolite Profile Approach to Target a Drug Delivery System Based on Magnetite Nanoparticles." Plants 10, no. 11 (2021): 2245. http://dx.doi.org/10.3390/plants10112245.

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The metabolites profile of a plant is greatly influenced by geographical factors and the ecological environment. Various studies focused on artemisinin and its derivates for their antiparasitic and antitumoral effects. However, after the isolation and purification stage, their pharmaceutical potential is limited due to their low bioavailability, permeability and lifetime. The antibacterial activity of essential oils has been another topic of interest for many studies on this plant. Nevertheless, only a few studies investigate other metabolites in Artemisia annua. Considering that secondary met

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22

Ding, Shu, Lin Zhao, Yun Qi, and Qian-qian Lv. "Preparation and Characterization of Lecithin-Nano Ni/Fe for Effective Removal of PCB77." Journal of Nanomaterials 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/678489.

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A kind of combined material (named lecithin-nano Ni/Fe) that is composed of lecithin and nanoscale Ni/Fe bimetal was synthesized via microemulsion method. The efficacy of such an original material was tested using 3,3′,4,4′-tetrachlorobiphenyl (PCB77) as target pollutant. A microemulsion system was optimized as template to prepare Ni/Fe nanoparticles, which was followed by an insite loading process with the deposition of lecithin carrier. It was proved by the characterization that subtle Ni/Fe nanoparticles can be uniformly dispersed and closely combined with lecithin carrier. Lecithin was an

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Thirunavukkarasu, M., and K. S. Subramanian. "Surface modified nano-zeolite used as carrier for slow release of sulphur." Journal of Applied and Natural Science 6, no. 1 (2014): 19–26. http://dx.doi.org/10.31018/jans.v6i1.369.

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Surface modified nano-zeolite (SMNZ) was used as carrier to develop nano-zeolite based nano-sulphur fertilizer. A laboratory study on sulphur nano-fertilizer and conventional sulphur fertilizer were studied with percolation reactor system to evaluate the slow release of sulphur from both fertilizers in ambient temperature. SMNZ and sulphur nano-fertilizer were characterized using Fourier Transform Infrared Spectroscopy (FT-IR), Zeta Analyzer, Raman Spectroscopy, XRD and Scanning Electron Microscope (SEM). Raman spectroscopy confirmed the sulphur attachment at 480 cm-1 in the SMNZ. The FTIR spe

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Motamed Fath, P., M. Rahimnejad, S. Moradi-kalbolandi, B. Ebrahimi Hosseinzadeh, and T. Jamshidnejad-tosaramandani. "Improvement of cytotoxicity and necrosis activity of ganoderic acid a through the development of PMBN-A.Her2-GA as a targeted nano system." RSC Advances 12, no. 2 (2022): 1228–37. http://dx.doi.org/10.1039/d1ra06488f.

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Shaw, S., P. Singh, R. Mishra, R. Singh, R. Nayak, and S. Bose. "Cancer therapeutics strategy using nano-carrier mediated natural drugs." Journal of Achievements in Materials and Manufacturing Engineering 114, no. 1 (2022): 32–41. http://dx.doi.org/10.5604/01.3001.0016.1481.

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Nucleolin is a multifactorial protein, having a significant role in chromatin remodelling, mRNA stability, ribosome biogenesis, stemness, angiogenesis, etc., thus, it is potential therapeutic target in cancer. The purpose of this paper is to study porous silicon (pSi) nanocarrier-based natural drug delivery system targeting dysregulated nucleolin expression for cancer therapeutics. Quercetin was loaded in pre-synthesized and characterized pSi nanoparticles, and release kinetics was studied. The study compared the inhibitory concentration (IC50) of quercetin, synthetic drug doxorubicin, and que

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Donthi, Mahipal Reddy, Siva Ram Munnangi, Kowthavarapu Venkata Krishna, Ranendra Narayan Saha, Gautam Singhvi, and Sunil Kumar Dubey. "Nanoemulgel: A Novel Nano Carrier as a Tool for Topical Drug Delivery." Pharmaceutics 15, no. 1 (2023): 164. http://dx.doi.org/10.3390/pharmaceutics15010164.

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Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes poor solubility, unpredictable absorption, and low oral bioavailability. Nano-emulgel, an amalgamated preparation of different systems aims to deal with these limitations. The novel system prepared by the incorporation of nano-emulsion into gel improves stability and enables drug delivery for both immediate and controlled release. The focus on nano-emulgel has also increased due to its ability to achieve targeted

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Abdalameer, N. Kh, S. N. Mazhir, H. M. Salim, J. Kh Hammood, and Z. H. Abdul Raheem. "Design of micro-jet plasma system: a novel nanoparticles manufacturing method in atmospheric pressure." Journal of Optoelectronic and Biomedical Materials 14, no. 4 (2022): 203–10. http://dx.doi.org/10.15251/jobm.2022.144.203.

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Micro jet atmospheric (MPJ) plasma was first utilized to create nano-sized crystals. Nanosized particles may have advantageous characteristics such as better internal quality and dissolving rates of the product compared to traditional crystalline goods. A nebulizer system sprays an aerosol solution into plasma by use of a carrier gas in a cold plasma crystal (argon). The plasma warms and loads the droplets causing solvent and columbic fission evaporation, and then the nucleation and crystal formation start within the limited volume given by the tiny drops. This produces nano-sized crystals. MP

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Abdul Azeez, Nazeer, Krishnaswami Venkateshwaran, Ruckmani Kandasamy, Muthupandian Saravanan, and Vijaykumar Sudarshana Deepa. "Importance of nano-carriers, surfactant system, and their loading mechanism to improve the absorption and bio-availability of drugs: a review." Advances in Natural Sciences: Nanoscience and Nanotechnology 15, no. 3 (2024): 033002. http://dx.doi.org/10.1088/2043-6262/ad6cbf.

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Abstract Improving the apparent solubility of poorly soluble therapeutic molecules with poor absorption into the circulatory system is a significant research question in drug discovery. This enhancement is achieved by delivering drugs through nano-carriers that provide apparent solubility with its surfactant. The effectiveness of a nano-carrier is relied majorly on its loading efficiency which is determined by the extent of interaction between the drug and the surfactants of the carriers. The loading effectiveness can be reckoned with a better understanding of the drug-surfactant conjugation m

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Jiang, Kai, Ting Chi, Tao Li, et al. "Correction: A smart pH-responsive nano-carrier as a drug delivery system for the targeted delivery of ursolic acid: suppresses cancer growth and metastasis by modulating P53/MMP-9/PTEN/CD44 mediated multiple signaling pathways." Nanoscale 10, no. 13 (2018): 6212–13. http://dx.doi.org/10.1039/c8nr90055h.

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Correction for ‘A smart pH-responsive nano-carrier as a drug delivery system for the targeted delivery of ursolic acid: suppresses cancer growth and metastasis by modulating P53/MMP-9/PTEN/CD44 mediated multiple signaling pathways’ by Kai Jiang et al., Nanoscale, 2017, 9, 9428–9439.

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Lu, Lidan, Ximei Cai, Luqin Guo, et al. "Fabrication of Quercitrin Nano Micellar Delivery System and Its Therapeutic Effect on Unexplained Recurrent Abortion." Journal of Biomedical Nanotechnology 18, no. 5 (2022): 1449–59. http://dx.doi.org/10.1166/jbn.2022.3328.

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We prepared a quercitrin nano micellar delivery system in this study to evaluate its oral bioavailability. The optimal formulation of quercetin nano micelles was determined through an orthogonal test. Characteristics (size of particles-SOP, morphology, efficiency of encapsulation-EE and stability) and the therapeutic property of quercitrin nano micelles on unexplained recurrent abortion (URSA) were evaluated. The SOP of quercitrin nano micelles was 111.88±3.70 nm with an EE of 95.66±0.57. A substantially increased release rate of quercetin from the micellar system was observed in different dis

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Joginder, Nagar, and Anupama Anand. "Recent Application of Nanotechnology in Drug Delivery System." Scholars Academic Journal of Pharmacy 11, no. 9 (2022): 155–60. http://dx.doi.org/10.36347/sajp.2022.v11i09.006.

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Nanoparticle drug delivery system is used for drug delivery applications in nanomedicine because of beneficial properties, such as better encapsulation, bioavailability, control release, and lower toxic effect. Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nano scale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. There are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunothera

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Boudovitch, Dmitri, Aya Sakaya, Arife Uzundurukan, Jean-Yve Leroux, and Domenico Fuoco. "Review of commercially available nano-drugs and nano-delivery systems: challenges and perspectives." 4open 6 (2023): 9. http://dx.doi.org/10.1051/fopen/2024002.

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Nano-drugs and nano-delivery systems are rapidly evolving, with new strategies emerging in the current practices. The evolution of these technologies began with modifying the chemical structure, progressing to supramolecular ionic complexes, and culminating in elegant ad hoc delivery systems. Nanoparticles have numerous benefits as a carrier system for delivering therapeutic agents to intra-arterial sites. These benefits include their subcellular size, targeted surfaces, good suspensibility, and uniform dispersity, making them an ideal choice for catheter-based delivery. Despite the advancemen

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Shen, Yue, Huaxin Zhu, Jianxia Cui, et al. "Construction of Lambda-Cyhalothrin Nano-Delivery System with a High Loading Content and Controlled-Release Property." Nanomaterials 8, no. 12 (2018): 1016. http://dx.doi.org/10.3390/nano8121016.

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Traditional pesticide formulations are limited by large organic solvent consumption, poor dispersibility, and poor foliar adhesion, resulting in low effective pesticides utilization and environmental pollution. To prolong the foliar pesticide retention and release time, a high lambda-cyhalothrin (LC)-loaded nano-delivery system was constructed, using polylactic acid (PLA) as a carrier through a solvent evaporation method. The obtained results showed that the stabilizer concentration, water–oil ratio, and carrier content exert a major influence on the LC loading, particle size, and size distrib

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Cui, Ling Yuan, Yan Hui Li, Wei Zhang, Jing Peng Zhang, and Qian Duan. "Hyaluronic Acid Functionalized Porous Silica Nanoparticles for Drug Delivery and Release." Advanced Materials Research 936 (June 2014): 322–26. http://dx.doi.org/10.4028/www.scientific.net/amr.936.322.

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In this paper, we reported a facile strategy to synthesize hyaluronic acid (HA) conjugated porous silica nanoparticles (pSiO2) as drug carrier. The pSiO2 were prepared by solid nano-silica nanoparticles with “surface-protected etching”. Morphologies of solid and porous silica nanoparticles were characterized by SEM and TEM. Amino groups were introduced on pSiO2 to graft HA as cancer targeting ligand. Then rifampicin used as model drug was loaded in pSiO2-HA. The results indicate that pSiO2 can perform a certain degree of slow release. Overall, the system might open the door to a new generation

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O.P, Oladipo, Amolegbe S.A, Ademowo O.G, and A.Y Bamigboye. "Synthesis and Characterizations of Mesoporous Silica Nanoparticles Antimalarial (Arthemeter) Drug Delivery System." International Journal of Innovative Science and Research Technology 7, no. 12 (2022): 454–58. https://doi.org/10.5281/zenodo.7485292.

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Malaria is endemic and a life-threatening disease been caused by the bite of a female anopheles mosquito which destroys the red blood cells. Nano carrier drug delivery system is of great interest in malaria research for improving the quality of health care delivery. This research work focused on development of inorganic silica nanoparticles as efficient delivery system for antimalarial drug of Arthemeter (ATM). The mesoporous silica nanoparticles (MSNPs) both amino modified mobile crystalline matter (aMCM-41) and mobile crystalline matter (MCM-41) were synthesized by co-condensation and sol-ge

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HU, XiaoQin, MingYuan LI, XingGuo MEI, GuangYu GAO, Cheng LIU, and SiYu MA. "Initial analysis of nano carrier targeted drug delivery system: misunderstanding, barriers and strategy." SCIENTIA SINICA Vitae 46, no. 11 (2016): 1249–58. http://dx.doi.org/10.1360/n052016-00219.

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Moghaddam, P. Hadipour, V. Ramezani, E. Esfandi, et al. "Development of a nano–micro carrier system for sustained pulmonary delivery of clarithromycin." Powder Technology 239 (May 2013): 478–83. http://dx.doi.org/10.1016/j.powtec.2013.02.025.

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KIRAN, KULKARNI SACHIN LOKAPURE AMRUTA TIDAKE. "A BRIEF REVIEW ON ROLE OF NANOCARRIER AS ANTIHYPERTNESIVE AGENTS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6973–87. https://doi.org/10.5281/zenodo.2619939.

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Now days Hypertension or high blood pressure is a common chronic heart disease. It is associated with various symptoms like amnesia, improper speech, blindness, peripheral artery disease, brain stroke, heart attack etc. it mainly involves the role of autonomous nervous system, cardiac output and renin-angiotensin aldosterone system. The present study mainly deals with the application of nanotechnology and nanoparticulate drug delivery systems in the formulation of various antihypertensive drugs for the treatment of hypertension. Applications of various nanoparticulate drug delivery systems lik

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Liu, Hui, Peng Zhang, Fang Zhang, and Qing Liu. "The Effects of Nanometer Titanium Dioxide on Tumor Cells and in Rats with Nasopharyngeal Carcinoma." Nanoscience and Nanotechnology Letters 12, no. 12 (2020): 1431–37. http://dx.doi.org/10.1166/nnl.2020.3250.

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A drug delivery system based on nanomaterials has demonstrated a powerful function in disease treatment. In this study, a titanium-dioxide-nanotube-based cisplatin (nano-TiO2-DDP) delivery system was designed, and its effects in rats with nasopharyngeal carcinoma (NPC) and on tumor cells were analyzed. First, we obtained electrochemistry anodic oxidation (EAO) for the preparation of Nnano-TiO2, which was adopted as the carrier of cisplatin (CDDP). Then, we used a scanning electron microscope (SEM) to characterize and study the surface morphology of nano-TiO2. At the cellular level, flow cytome

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Choi, Won Il, Gi Yoong Tae, and Young Ki Hong. "Study of the enzymatic action of the chymopapain using pluronic based nano-carrier system on the cadaveric nucleus pulposus tissue." Journal of the Korea Academia-Industrial cooperation Society 16, no. 1 (2015): 585–92. http://dx.doi.org/10.5762/kais.2015.16.1.585.

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Tonegawa, Toru, Toshiyuki Ikoma, Guo Ping Chen, and M. Tanaka. "Control of Protein Initial Burst from Zinc-Hydroxyapatite / Poly(L-Lactide) System." Key Engineering Materials 330-332 (February 2007): 857–60. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.857.

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Control of protein release without the initial burst from zinc containing hydroxyapatite porous microparticles (Zn-HAp) was investigated with a novel formulation method. The formulation method was a coat of polyL(L-lactide; PLA) on the microparticle with nano-thickness, which obviously suppressed the initial burst of protein release compared with the microparticles without the formulation, the coat of PLA. The HAp/PLA microparticle with 1-20μm of the size distribution was available for the drug delivery carrier of proteins without the degradation.

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Pioch, Tomas, Thorben Fischer, and Marc Schneider. "Aspherical, Nano-Structured Drug Delivery System with Tunable Release and Clearance for Pulmonary Applications." Pharmaceutics 16, no. 2 (2024): 232. http://dx.doi.org/10.3390/pharmaceutics16020232.

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Addressing the challenge of efficient drug delivery to the lungs, a nano-structured, microparticulate carrier system with defined and customizable dimensions has been developed. Utilizing a template-assisted approach and capillary forces, particles were rapidly loaded and stabilized. The system employs a biocompatible alginate gel as a stabilizing matrix, facilitating the breakdown of the carrier in body fluids with the subsequent release of its nano-load, while also mitigating long-term accumulation in the lung. Different gel strengths and stabilizing steps were applied, allowing us to tune t

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Zhang, Sufang, Qianru Wang, Bingbing Zhang, Hui Wen, and Yan’e Ma. "Construction and Efficacy of a Novel Treatment Against Acute Leukemia by Using Mesoporous Silica Nanoparticles and Arsenic." Journal of Biomedical Nanotechnology 19, no. 2 (2023): 273–79. http://dx.doi.org/10.1166/jbn.2023.3513.

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This study aimed to use mesoporous silica nanoparticles (MNPs) as the carrier material, and connect non-toxic and non-immunogenic polyethylene glycol (PEG) and arsenic trioxide (AO) as a novel treatment of acute leukemia in vitro. Silica was synthesized by co-precipitationmethod. Based on this, a redox-responsive carrier (MNPs-PEG) was synthesized. The drug loading of AO-loaded modified silica (MNPs-AO) and MNPs-PEG/AO were verified by thermogravimetric analyzer. The dialysis bag method was used to investigate the in vitro drug release characteristics of the drug delivery system under differen

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Liu, Langlang, Yanzeng Wu, Chao Xu, Suchun Yu, Xiaopei Wu та Honglian Dai. "Synthesis, Characterization of Nano-β-Tricalcium Phosphate and the Inhibition on Hepatocellular Carcinoma Cells". Journal of Nanomaterials 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/7083416.

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It is difficult to synthesize nano-β-tricalcium phosphate (nano-β-TCP) owing to special crystal habit. The aim of this work was to synthesize nano-β-TCP using ethanol-water system and characterize it by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Malvern laser particle size analyzer, and transmission electron microscope (TEM). In addition, the inhibitory effect of nano-β-TCP on human hepatocellular carcinoma (HepG2) cells was also investigated using MTT assay, lactate dehydrogenase (LDH) leakage test, and 4′-6-diamidino-2-phenylindole (DAPI) staining. The results s

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Unnati, Patel, Rathnayake Kavini, Jani Hemang, et al. "Near-infrared responsive targeted drug delivery system that offer chemo-photothermal therapy against bacterial infection." Nanoselect, no. 2 (March 10, 2021): 1750–69. https://doi.org/10.1002/nano.202000271.

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To combat the rise of antibiotic resistant bacteria, it is essential to look upon other therapeutic solutions that do not solely depend upon conventional antibiotics. Here, we have designed a combinational therapeutic approach that kills bacteria with the conjunction of photothermal (PT) and antibiotic therapy. A near-infrared (NIR) laser activated targeted drug delivery nano-assembly delivers antibiotic as well as offer PT therapy (PTT). The synergistic application of both therapies increases the efficacy of treatment. The protected delivery of antibiotic and its release in the proximity of t

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Sun, Gang, Jin Zhang, Shuai Wu та Yun Liu. "Experimental study on nuclear-targeted plasmid-based short hairpin RNA (ShRNA) to hypoxia inducible factor-1α (PshHIF-1α) PshHIF-1α nano-drug carrier system for breast cancer treatment in rats". Materials Express 11, № 7 (2021): 1045–50. http://dx.doi.org/10.1166/mex.2021.2029.

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This study was aimed at exploring the regulatory mechanism of auclear-targeted pshHIF-1α nano-drug carrier system (NPNCS) in the treatment of breast cancer in rats. MDA-MB-231 cell was cultured and DJ-1 and PTEN mRNA level was detected by qRT-PCR along with analysis of cell viability by CCK-8 and apoptosis by means of flow cytometry. The rats were assigned into control group, nuclear-targeted pshHIF-1α nanopharmaceutical system treatment group, and nuclear-targeted pshHIF-1α nano-pharmaceutical system+PTEN inhibitor SF1670 group, followed by analysis of cell proliferation by EdU staining, cell

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Agrawal, Mukta, Shailendra Saraf, Madhulika Pradhan, et al. "Design and optimization of curcumin loaded nano lipid carrier system using Box-Behnken design." Biomedicine & Pharmacotherapy 141 (September 2021): 111919. http://dx.doi.org/10.1016/j.biopha.2021.111919.

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Esmaili, Sayyed Kamiyar, Babak Ghanbarzadeh, Ali Ayaseh, Akram Pezeshki, and Mohammadyar Hosseini. "Design, fabrication and characterization of pectin-coated gelatin nanoparticles as potential nano-carrier system." Journal of Food Biochemistry 43, no. 2 (2018): e12729. http://dx.doi.org/10.1111/jfbc.12729.

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Ruirui, Zhang, Jian He, Ximei Xu, et al. "PLGA-based drug delivery system for combined therapy of cancer: research progress." Materials Research Express 8, no. 12 (2021): 122002. http://dx.doi.org/10.1088/2053-1591/ac3f5e.

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Abstract In recent years, PLGA micro/nano particle drug delivery systems has been widely used in cancer treatment. According to the unique properties of PLGA, carriers of various structures are designed to keep the function of drugs or bioactive substances, ensure the effective load of molecules and improve the bioavailability of drugs in diseased parts. PLGA is one of the earliest and most commonly used biodegradable materials. It is often used for functional modification with other polymers (such as polyethylene glycol and chitosan) or other molecules (such as aptamers and ligands) to delive

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Hasanah, Yunca Muhimatul, Sri Raharjo, Pranoto Y, and Ningrum A. "APLIKASI NANO-SIZE LIPID CARRIER (NLC) MINYAK BEKATUL (RBO) PADA MINUMAN SARI BUAH APEL DAN JERUK KOMERSIAL." Journal of Nutrition College 13, no. 1 (2024): 38–48. http://dx.doi.org/10.14710/jnc.v13i1.41713.

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ABSTRACTBackground: Rice bran oil contains high amounts of bioactive component compounds. This compound has activity as a natural antioxidant, especially α, β, γ, δ tocopherol and tocotrienol, as well as orizanol fraction. The properties of γ-orizanol as a fat-soluble antioxidant become a limitation when applied to liquid food or beverages. Therefore, a carrier system is needed to support γ-orizanol well dispersed in the beverage system. The lipid-based carrier system is divided into Solid Lipid Nanoparticles, Nanostructured Lipid Carrier and Nanoemulsion. In this study using NLC as a carrier

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