Relevant bibliographies by topics / Nanocarriers Dendrimers

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Academic literature on the topic 'Nanocarriers Dendrimers'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Nanocarriers Dendrimers"

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Zahoor, Ishrat, Sukhbir Singh, Neelam Sharma, Tapan Behl, and Shahid Nazir Wani. "Dendrimers: Versatile and Revolutionary Nanocarriers for Infectious Diseases." ECS Transactions 107, no. 1 (2022): 8619–30. http://dx.doi.org/10.1149/10701.8619ecst.

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Dendrimers, type of revolutionary nanomolecules, have gained a lot of popularity in recent years. These compounds can be developed and transformed in a variety of ways to produce a molecule that fulfills the requirements. As a result, dendrimers are the subject of extensive research in a variety of nanoscience domains, including one of the most promising biomedicine. Dendrimers are polymeric nanoparticles offering a huge number of benefits in biomedicine because of their nanometric dimensions, biocompatibility, multivalency, and structural perfection. In this review, we provide an overview of
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Szota, Magdalena, Katarzyna Reczyńska-Kolman, Elżbieta Pamuła, Olga Michel, Julita Kulbacka, and Barbara Jachimska. "Poly(amidoamine) Dendrimers as Nanocarriers for 5-Fluorouracil: Effectiveness of Complex Formation and Cytotoxicity Studies." International Journal of Molecular Sciences 22, no. 20 (2021): 11167. http://dx.doi.org/10.3390/ijms222011167.

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Two generations of positively charged poly(amidoamine) dendrimers (PAMAMs) were selected for study as potential carriers for the anticancer drug 5-fluorouracil (5FU), a drug primarily used in the treatment of colorectal cancer. Analytical techniques, such as UV-Vis spectrophotometry, NMR Spectroscopy and Laser Doppler Velocimetry (LDV), have shown that the most critical factor determining the formation of a PAMAM–5FU complex is the starting components’ protonation degree. The tests confirmed the system’s ability to attach about 20 5FU molecules per one dendrimer molecule for the G4PAMAM dendri
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Sk, Ugir Hossain, and Chie Kojima. "Dendrimers for theranostic applications." Biomolecular Concepts 6, no. 3 (2015): 205–17. http://dx.doi.org/10.1515/bmc-2015-0012.

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AbstractRecently, there have been tremendous advances in the development of various nanotechnology-based platforms for diagnosis and therapy. These nanoplatforms, which include liposomes, micelles, polymers, and dendrimers, comprise highly integrated nanoparticles that provide multiple functions, such as targeting, imaging, and therapy. This review focuses on dendrimer-based nanocarriers that have recently been developed for ‘theranostics (or theragnosis)’, a combination of therapy and diagnostics. We discuss the in vitro and in vivo applications of these nanocarriers in strategies against dis
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Sheveleva, Nadezhda N., Denis A. Markelov, Mikhail A. Vovk, et al. "Stable Deuterium Labeling of Histidine-Rich Lysine-Based Dendrimers." Molecules 24, no. 13 (2019): 2481. http://dx.doi.org/10.3390/molecules24132481.

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Peptide dendrimers, due to their biocompatibility and low toxicity, are highly promising candidates as nanocarriers for drugs and genes. The development of this kind of delivery system requires reliable monitoring of their metabolic and biological pathways. In this respect, hydrogen isotope labeling has tremendous importance, being a safe tool for detection of the labeled nanocarriers. In this work, we have synthesized new histidine-rich lysine-based dendrimers (Lys-2His dendrimer) with two linear histidine (His) residues in every inner segment. The presence of His residues has enabled us to p
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Concellón, Alberto, María San Anselmo, Silvia Hernández-Ainsa, Pilar Romero, Mercedes Marcos, and José Luis Serrano. "Micellar Nanocarriers from Dendritic Macromolecules Containing Fluorescent Coumarin Moieties." Polymers 12, no. 12 (2020): 2872. http://dx.doi.org/10.3390/polym12122872.

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The design of efficient drug-delivery vehicles remains a big challenge in materials science. Herein, we describe a novel class of amphiphilic hybrid dendrimers that consist of a poly(amidoamine) (PAMAM) dendritic core functionalized with bisMPA dendrons bearing cholesterol and coumarin moieties. Their self-assembly behavior both in bulk and in water was investigated. All dendrimers exhibited smectic A or hexagonal columnar liquid crystal organizations, depending on the generation of the dendrimer. In water, these dendrimers self-assembled to form stable spherical micelles that could encapsulat
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Prafulla, Patil* Dr. Shivshankar Mhaske Pankaj Fitave Dipak Sontakke Om Lole Akash Parihar Vaibhav Chaudhary. "Nanocarriers Dendrimers for New Tuberculosis Therapy." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4659–80. https://doi.org/10.5281/zenodo.15542547.

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Tuberculosis (TB) is a contagious infection that usually attacks not only the lungs, but also brain and spine. More than twenty drugs have been developed for the treatment of TB, but most of them were developed some years ago. They are used in different combinations. Isoniazid and Rifampicin are examples of the five first line TB drugs, whereas, for instance, Levofloxacin, Kanamycin and Linezolid belong to the second line drugs that are used for the treatment of drug resistant TB. Several new bicyclic nitroimidazoles (e.g., Delamanid) without mutagenic effects were developed. New TB drugs need
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Jeevanandam, Jaison, Kei Xian Tan, João Rodrigues, and Michael K. Danquah. "Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles." Pharmaceutics 15, no. 6 (2023): 1614. http://dx.doi.org/10.3390/pharmaceutics15061614.

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Nanosized Janus and dendrimer particles have emerged as promising nanocarriers for the target-specific delivery and improved bioavailability of pharmaceuticals. Janus particles, with two distinct regions exhibiting different physical and chemical properties, provide a unique platform for the simultaneous delivery of multiple drugs or tissue-specific targeting. Conversely, dendrimers are branched, nanoscale polymers with well-defined surface functionalities that can be designed for improved drug targeting and release. Both Janus particles and dendrimers have demonstrated their potential to impr
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Geiger, Brett C., Sheryl Wang, Robert F. Padera, Alan J. Grodzinsky, and Paula T. Hammond. "Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis." Science Translational Medicine 10, no. 469 (2018): eaat8800. http://dx.doi.org/10.1126/scitranslmed.aat8800.

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Osteoarthritis is a debilitating joint disease affecting nearly 30 million people for which there are no disease-modifying therapies. Several drugs that have failed clinical trials have shown inefficient and inadequate delivery to target cells. Anabolic growth factors are one class of such drugs that could be disease-modifying if delivered directly to chondrocytes, which reside deep within dense, anionic cartilage tissue. To overcome this biological barrier, we conjugated a growth factor to a cationic nanocarrier for targeted delivery to chondrocytes and retention within joint cartilage after
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Sarkhel, Shounak, Saikat Mollick Shuvo, Md Ahesan Ansari, et al. "Nanotechnology-Based Approaches for the Management of Diabetes Mellitus: An Innovative Solution to Long-Lasting Challenges in Antidiabetic Drug Delivery." Pharmaceutics 16, no. 12 (2024): 1572. https://doi.org/10.3390/pharmaceutics16121572.

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Diabetes is a widespread metabolic illness. Mismanagement of diabetes can lead to severe complications that tremendously impact patients’ quality of life. The assimilation of nanotechnology in diabetes care holds the potential to revolutionize treatment paradigms, improve patient outcomes, and reduce the economic burden associated with this pervasive disease. This manuscript explores the multifaceted utilization of nanomaterials in diabetes care, emphasizing the unique features of nano-based medication delivery methods and smart drug delivery mechanisms. Additionally, this paper talks about re
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Florendo, Maria, Alexander Figacz, Bhairavi Srinageshwar, et al. "Use of Polyamidoamine Dendrimers in Brain Diseases." Molecules 23, no. 9 (2018): 2238. http://dx.doi.org/10.3390/molecules23092238.

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Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and surface functional groups) can be precisely modulated to yield a variety of nanocarriers for delivery of drugs and genes to brain cells in vitro or in vivo. Two of the most important criteria to consider when using PAMAM dendrimers for neuroscience applications is their safety profile and their potential to be prepared in a reproducible manner
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Dissertations / Theses on the topic "Nanocarriers Dendrimers"

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Wang, Yang. "Novel amphiphilic dendrimers as nanovectors for siRNA delivery." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4017.

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Les dendrimères, font partie d'une famille particulière de polymères synthétiques, pouvant être utilisés comme nanovecteurs pour l'administration de médicaments grâce à leur structure polyvalente et leur action coopérative, ces fonctions étant confinées dans un volume de taille nanométrique. Notre groupe a récemment démontré que de petites unités dendritiques amphiphiles pouvaient s'auto-assembler en dendrimères supramoléculaires pouvant délivrer du siARN, avec une efficacité similaire à celle des dendrimères de grande génération construits de manière covalente. Dans cette thèse, ans le but de
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Wang, Yang. "Novel amphiphilic dendrimers as nanovectors for siRNA delivery." Electronic Thesis or Diss., Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4017.

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Les dendrimères, font partie d'une famille particulière de polymères synthétiques, pouvant être utilisés comme nanovecteurs pour l'administration de médicaments grâce à leur structure polyvalente et leur action coopérative, ces fonctions étant confinées dans un volume de taille nanométrique. Notre groupe a récemment démontré que de petites unités dendritiques amphiphiles pouvaient s'auto-assembler en dendrimères supramoléculaires pouvant délivrer du siARN, avec une efficacité similaire à celle des dendrimères de grande génération construits de manière covalente. Dans cette thèse, ans le but de
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Marson, Domenico. "Coupling of experimental and computational approaches for the development of new dendrimeric nanocarriers for gene therapy." Doctoral thesis, Università degli studi di Trieste, 2015. http://hdl.handle.net/10077/11803.

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2013/2014<br>Gene therapy is increasingly critical in the treatment of different types of maladies. The approach of gene therapy can be fundamental in dealing with many kinds of tumors, viral infections (e.g., HIV, HSV), and disturbs linked to genetic anomalies. However, the use of nucleic acids is limited by their ability to reach their action site—the target cell and, often, the inside of its nucleus. Dendrimers, on the other hand, are an interesting kind of polymers, the general synthetic scheme of which is relatively of recent development (∼1980). Among the many possible uses of these pol
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Chen, Liang. "Synthèse et applications biologiques de dendrimères et dendrons phosphorés." Thesis, Toulouse 3, 2020. http://www.theses.fr/2020TOU30277.

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L'objectif de ces travaux était de concevoir plusieurs familles de dendrimères phosphorés cationiques et de dendrons neutres et cationiques, et d'étudier leur potentiel dans le domaine de la biologie/nanomédecine. Premièrement, nous avons revisité les dendrimères phosphorés cationiques comme vecteur non viral pour le transport de gènes contre le cancer. L'efficacité d'expression des gènes a été détectée par microscopie à fluorescence, cytométrie en flux, réaction en chaîne de polymérase quantitative en temps réel (rt-qPCR) et tests Western blot. Les résultats révèlent que dans les conditions o
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Magatti, Cecilia. "Computational modelling to characterize dendrimer nanocarriers for siRNA delivery in chronic obstructive pulmonary disease." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13647/.

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La Broncopneumopatia Cronica Ostruttiva (BPCO) è un’infiammazione polmonare progressiva caratterizzata da limitazione di flusso espiratorio. Ad oggi a livello mondiale si stima che 328 milioni di persone siano affette da BPCO e si prevede che diventi la quarta causa di morte entro il 2030 con più di 65 milioni di casi l’anno. Il successo dei trattamenti medici mediante acidi nucleici, come DNA e silencing interference RNA è fortemente legato al design di efficienti tecnologie di rilascio. I dendrimeri cationici rappresentano un’interessante possibilità come vettori grazie a noti vantaggi di
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Tang, Jingjie. "Innovative imaging systems and novel drug candidates for cancer therapy." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4021.

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Le cancer est l'une des principales causes de décès dans le monde et reste une maladie difficile à traiter du fait des difficultés de pronostic, du développement rapide de métastases et de la résistance aux médicaments. Il en résulte une forte demande en méthodologies d'imagerie innovantes pour le diagnostic précoce et précis ainsi qu’en nouveaux agents anticancéreux possédant de nouveaux mécanismes pour surmonter la résistance aux médicaments. Le but de mon projet de recherche de doctorat était donc de contribuer à cet objectif.La première partie de ma thèse de doctorat a porté sur la créatio
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Tang, Jingjie. "Innovative imaging systems and novel drug candidates for cancer therapy." Electronic Thesis or Diss., Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4021.

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Le cancer est l'une des principales causes de décès dans le monde et reste une maladie difficile à traiter du fait des difficultés de pronostic, du développement rapide de métastases et de la résistance aux médicaments. Il en résulte une forte demande en méthodologies d'imagerie innovantes pour le diagnostic précoce et précis ainsi qu’en nouveaux agents anticancéreux possédant de nouveaux mécanismes pour surmonter la résistance aux médicaments. Le but de mon projet de recherche de doctorat était donc de contribuer à cet objectif.La première partie de ma thèse de doctorat a porté sur la créatio
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Heyder, Rodrigo dos Santos. "Poliésteres dendríticos: aplicações em sistemas de drug delivery e magnificação de efeito catalítico." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-18082016-080613/.

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Materiais altamente especializados (polifuncionais) continuam a ser candidatos chave para avanços na área tecnológica e biológica. Buscando aplicação em campos diversos, foram sintetizadas estruturas dendríticas (dendrímeros e polímeros hiperramificados) do tipo poliéster. Esses materiais foram utilizados para dois fins distintos, a aplicação em sistemas de Drug Delivery e em sistemas catalíticos. Em relação aos sistemas de Drug Delivery, foram estudados dois aspectos principais: (i) Impregnação de fármacos na matriz dendrimérica utilizando scCO2 como solvente - foi estudado o comportamento do
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Gouveia, Maria Ana Nova Morais Gramaxo. "Exploring the potential of fully Biodegradable PEG-Dendrimers as Nanocarriers of Different siRNA Sequences for Dual Delivery." Master's thesis, 2020. https://hdl.handle.net/10216/130913.

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Gouveia, Maria Ana Nova Morais Gramaxo. "Exploring the potential of fully Biodegradable PEG-Dendrimers as Nanocarriers of Different siRNA Sequences for Dual Delivery." Dissertação, 2020. https://hdl.handle.net/10216/130913.

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Book chapters on the topic "Nanocarriers Dendrimers"

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Kolhatkar, Rohit, Deborah Sweet, and Hamidreza Ghandehari. "Functionalized Dendrimers as Nanoscale Drug Carriers." In Multifunctional Pharmaceutical Nanocarriers. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76554-9_7.

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Mohammed, Arab Iram Saba Gaus, Victor Hmingthansanga, Sivakumar Manickam, V. Ravichandiran, and Subramanian Natesan. "Potential of Dendrimers as Nanocarriers for Brain Drug Delivery." In Nanocarriers in Neurodegenerative Disorders. CRC Press, 2024. http://dx.doi.org/10.1201/9781003383376-16.

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Gothwal, Avinash, Ashok Kumar Sharma, Gurjit Kaur Bhatti, and Umesh Gupta. "Dendrimers as Promising Nanocarriers in Drug Delivery." In NanoBioEngineering. CRC Press, 2018. http://dx.doi.org/10.1201/9781351138901-3.

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Pathak, Anchal, Saba Naqvi, and Keerti Jain. "Functionalized Dendrimers: Promising Nanocarriers for Theranostic Applications." In Multifunctional And Targeted Theranostic Nanomedicines. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0538-6_8.

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Kumar, Vinay, Rakesh Kumar Sahoo, Sanya Batheja, and Umesh Gupta. "Potential of Dendrimers as Nanocarrier for Brain Delivery." In Application of Nanocarriers in Brain Delivery of Therapeutics. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2859-6_8.

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Oliveira, Joaquim M., João F. Mano, and Rui L. Reis. "Progress in Dendrimer-Based Nanocarriers." In Biomimetic Approaches for Biomaterials Development. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527652273.ch19.

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Gardikis, Konstantinos, Sophia Hatziantoniou, Kyriakos Viras, Matthias Wagner, and Costas Demetzos. "Interaction of Dendrimers with Model Lipid Membranes Assessed by DSC and Raman Spectroscopy." In Nanocarrier Technologies. Springer Netherlands, 2006. http://dx.doi.org/10.1007/978-1-4020-5041-1_12.

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Müllerová, M., and T. Strašák. "Dendrimers." In Characterisation of Drug Nanocarriers. Royal Society of Chemistry, 2024. https://doi.org/10.1039/9781837672981-00209.

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Dendrimers are radially symmetric, nano-sized molecules with well-defined, monodisperse structures with advantageous properties for biomedicinal applications. In this chapter, we review recent developments from investigations on dendrimers focused predominantly on drug loading and delivery. Attention is given, among others, to encapsulation approaches and characterization of conjugates of dendrimers, not only with drug molecules but also genetic material and imaging agents.
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Zhang, Tingbin, Chunqiu Zhang, Jinfeng Xing, et al. "Multifunctional Dendrimers for Drug Nanocarriers." In Materials Science and Engineering. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1798-6.ch018.

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Dendrimers are nanosized, monodisperse, highly branched polymers with well-defined topological structure which have attracted much attention for drug delivery recently. To further improve the performance of dendrimers in drug delivery, various functional dendrimers are developed by decorating the dendrimers with targeting agents, imaging agents, or stimuli-sensitive moieties. They show good biocompatibility, visibility, tumor targeting and stimuli-sensitive properties for drug or gene delivery. This chapter will focus on the design of multifunctional nanocarriers based on the dendrimers. There
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Zhang, Tingbin, Chunqiu Zhang, Jinfeng Xing, et al. "Multifunctional Dendrimers for Drug Nanocarriers." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0751-2.ch010.

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Dendrimers are nanosized, monodisperse, highly branched polymers with well-defined topological structure which have attracted much attention for drug delivery recently. To further improve the performance of dendrimers in drug delivery, various functional dendrimers are developed by decorating the dendrimers with targeting agents, imaging agents, or stimuli-sensitive moieties. They show good biocompatibility, visibility, tumor targeting and stimuli-sensitive properties for drug or gene delivery. This chapter will focus on the design of multifunctional nanocarriers based on the dendrimers. There
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