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Dissertations / Theses on the topic 'Nanoencapsulation'

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1

Iwu, Kingsley Odinaka. "Nanoencapsulation of luminescent lanthanide complexes." Master's thesis, Universidade de Aveiro, 2006. http://hdl.handle.net/10773/2260.

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Mestrado em Ciência dos Materiais<br>Nanopartículas de sílica e titânia foram usadas para encapsulamento de complexos lantanídeos (Ln) de 3-hidroxipicolinato e picolinato, sintetizados por hidrólise de alcóxidos por meio de micelas invertidas – microemulsão de óleo em água, estabilizada com um agente surfactante, em que a fase aquosa existe na forma de domínios nanométricos. A alteração da dimensão destes domínios aquosos ou nano-reactores, conseguida variando a quantidade de água e mantendo constante a concentração de surfactante, determina aproximadamente o tamanho das partículas formadas no
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2

Yap, Aaron J. "Hydrogenolysis, hydrogenation and nanoencapsulation in cascade reactions." Thesis, The University of Sydney, 2012. https://hdl.handle.net/2123/29153.

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Catalytic nanoreactors, prepared by the Layer-by-Layer encapsulation of zeolite H-Beta, were used in the dynamic kinetic resolution (DKR) of 1-phenylethanol and 1-indanol. Yields for both alcohols were clearly above 50%, with ee’s over 85%, indicating successful protection of the pH-sensitive enzyme, candida antarctica lipase B, from the acidic zeolite. Attention proceeded to the DKR of amines, which can involve the undesired hydrogenolysis reaction during the racemisation step. Thus, the phenomenon of hydrogenolysis was investigated. The hydrogenolysis of various amines, imines, and
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3

Sessa, Mariarenata. "Nanoencapsulation of bioactive compounds for food applications." Doctoral thesis, Universita degli studi di Salerno, 2012. http://hdl.handle.net/10556/315.

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2010 - 2011<br>The increase in dietary-intake-related illnesses, such as obesity, cardiovascular diseases, hypertension, diabetes and cancer, have made in recent years the development of health-and-wellness promoting foods a priority of the food industry. Clinical studies have demonstrated tangible health benefits that may be derived from the intake of bioactive compounds. However many difficulties are associated with their inclusion in food matrices, due to a very low solubility in water and easy degradation by hostile environmental conditions once extracted from plant tissues. Furthermore, p
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4

De, Zayas Rosaura. "Detection and neutralization of bacterial biohazards via nanoencapsulation." FIU Digital Commons, 2006. http://digitalcommons.fiu.edu/etd/2757.

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Bacteria biohazards, such as Anthrax, are responsible for causing mild to serious illnesses in humans and animals. The primary aim of this research study was to develop a rapid one step assay to detect and neutralize bacteria-based biohazards, using an Immunoliposome-nanoparticle complex. An Anthrax model, Bacillus cereus, was grown for 3 hours and diluted 1:25 in media (2.0 x 107 cfu/ml). The Bacillus cereus was interacted with an Immunoliposome-nanoparticle complex containing an MgO-C 2 neutralization agent. The samples were analyzed via flow cytometry with a 1:8:1 ratio Bacillus cereus, Imm
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5

Pfeilsticker, Neves Renata. "Glycated Bovine Serum Albumin for Curcumin Nanoencapsulation: Bio-Nano Interactions." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42583.

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Glycation of whey proteins results in food-grade composites with modified physicochemical properties. Here, the reaction between glucose and bovine serum albumin (BSA) is promoted under wet-heating conditions. The glycated protein is characterized in depth and compared to the native counterpart and the impact of glycation on properties like net surface charge, particle size and surface hydrophobicity are observed. Conjugation with glucose reduced the surface hydrophobicity of BSA but the interactions between albumin and curcumin became stronger, which contradicts the direct relationship betwee
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6

Fullagar, Bronwyn Anne. "Nanoencapsulation of bilirubin and its effects on isolated murine pancreatic islet cells." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429457854.

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7

Pérez, Masiá Rocío. "MICRO- AND NANOENCAPSULATION VIA ELECTRO-HYDRODYNAMIC PROCESSING OF INTEREST IN FOOD APPLICATIONS." Doctoral thesis, Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/39341.

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Micro- and nanoencapsulation have generated great interest over the last years in multiple fields. Particularly in the food industry, this technology presents potential applications for the development of smart packaging structures, as well as for the protection of sensitive ingredients and the production of novel healthy foods. Therefore, in this thesis, the development of different encapsulation structures of interest in the food area was carried out. Specifically, capsules were obtained through electrohydrodynamic processing, since this technology presents several advantages
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8

Massella, Daniele. "Preparation of biofunctional textiles by surface functionalization based on the nanoencapsulation technique." Thesis, Lille, 2020. http://www.theses.fr/2020LILUI077.

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La présente thèse a été réalisée dans le cadre du projet de doctorat joint SMD-Tex, en partenariat entre le POLITO (Italie), l’ENSAIT (France) et à l'Université de Soochow (Chine). Le but de ce travail est de proposer de nouvelles approches pour la production de textiles biofonctionnels. Ces produits sont constitués de textiles qui ont subi des traitements de finition spéciaux pour conférer des propriétés qui présentent des effets bénéfiques pour la santé de l'utilisateur.Longtemps la recherche pharmaceutique a étudié des outils nouveaux et plus efficaces pour administrer un médicament au pati
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MASSELLA, DANIELE. "Preparation of biofunctional textiles by surface functionalization based on the nanoencapsulation technique." Doctoral thesis, Politecnico di Torino, 2020. http://hdl.handle.net/11583/2858355.

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10

Yammine, Jina. "Nanoencapsulation of biosourced antimicrobials for a persistent disinfection of food contact surfaces." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILR037.

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La persistance des biofilms reste un problème mondial rencontré dans l'industrie agro-alimentaire. En raison de la résistance adaptative associée aux propriétés physiques de la matrice du biofilm, l'échec de l'éradication totale des biofilms à l'aide de désinfectants conventionnels souligne la nécessité de trouver des stratégies alternatives efficaces. La méthodologie développée dans ce travail est axée sur l'utilisation de terpènes d'huiles essentielles biosourcées, à savoir le carvacrol (CAR) et le thymol (THY), qui représentent de puissants antimicrobiens face aux biofilms. La nanoencapsula
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11

Luca, Alexandru. "Effect Of Nanoencapsulation Of Purified Polyphenolic Powder On Encapsulation Efficiency, Storage And Baking Stability." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614412/index.pdf.

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The primary objective of this study was to obtain nano-emulsion containing polyphenolic compounds extracted from sour cherry pomace and to investigate the effect of degritting of polyphenolic concentrates on the encapsulation efficiency and particle size distribution of capsules and emulsions. It was also aimed to study storage and baking stability of the capsules. Extracted polyphenolic concentrate was degritted at 10,000 rpm for 2 min. Purification reduced Sauter mean diameter (D[32]) of concentrated extract from 5.76 &mu<br>m to 0.41 &mu<br>m. Unpurified and purified concentrates were freez
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12

Silva, Larissa Morais Ribeiro da. "Bioactive compounds in pulps and byproducts of tropical fruits: quantification, antimicrobial activity and nanoencapsulation." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13081.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>Currently, there is a demand for natural antimicrobials for use in the food industry. Some tropical fruits have a promising potential , not investigated at the moment. This study aimed to identify and quantify resveratrol, quercetin and coumarin in pulps and byproducts of tropical fruits, develop nanoparticles with extracts that showed higher levels of these compounds and evaluate the antimicrobial activity against Listeria sp. and E. coli K12. The Surinam cherry and mango byproducts, as well as caja, acerola and Surinam cherry p
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Bouvet, Raphaël. "Traitement des ulcérations cutanées par nanoencapsulation d’agents actifs. Mise au point et preuve de concept." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAS018.

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La cicatrisation est un processus multifactoriel. Dans le cadre du diabète, on retrouve une altération des processus à l’œuvre lors de la cicatrisation. En effet, l’hyperglycémie chronique présente chez le patient diabétique modifie la fonction des tissus principalement au niveau endothélial ainsi qu’au niveau cutané.Les ulcères chroniques du patient diabétique sont un problème majeur de santé publique avec une thérapeutique actuelle limité en efficacité. Ils représentent un facteur majeur de détérioration de la qualité de vie avec un risque d’amputation des membres inférieurs important.Lors d
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14

CATALAN, LATORRE ANA. "Evaluation of natural compounds for inflammatory diseases and their improvement by nanoencapsulation in phospholipid systems." Doctoral thesis, Università degli Studi di Cagliari, 2018. http://hdl.handle.net/11584/255977.

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Pollution, poor nutrition, insufficient physical activity, and the use of tobacco and alcohol are the primary cause of most chronic and aging-related diseases. When an overload of these free radicals cannot be gradually destroyed by endogenous antioxidants, its accumulation generates a phenomenon called oxidative stress. This process negatively affects the equilibrium of local gut microbiota and leads to systemic oxidative damage of cellular biomolecules (lipids, proteins and nucleic acids), thus, playing a major role in the development of chronic and degenerative illness such as cancer, autoi
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15

Pitti, caballero Javier ernesto. "Nanoencapsulation d’un agent synergisant chimique, la deltaméthrine pour potentialiser l’effet d’un insecticide, l’indoxacarbe contre les insectes nuisibles." Thesis, Angers, 2019. http://www.theses.fr/2019ANGE0005.

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L’utilisation non raisonnée d’insecticides a des conséquences sur l’environnement et la santé humaine mais aussi sur le développement de résistances chez les insectes nuisibles. Dans ce contexte, ce travail de thèse porte sur le développement d'une technique de nanoencapsulation d'un agent synergisant chimique, la deltaméthrine (pyréthrinoide), associé un pro-insecticide l’indoxacarbe (oxadiazine). Sur la base d’études in vitro sur cellules neurosecrétrices de blattes (Periplaneta americana), une action synergique entre la deltaméthrine et le DCJW (métabolite actif de l’indoxacarbe) a été démo
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16

Zhao, Shuting zhao. "Bioinspired Multiscale Biomaterials for Cell-Based Medicine." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1469100304.

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17

Moulari, Brice. "Propriétés antimicrobiennes in vitro d'extraits de deux plantes africaines : rôle de l'astilbine : potentialisation du pouvoir antibactérien par nanoencapsulation." Besançon, 2005. http://www.theses.fr/2005BESA3004.

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L'émergence de plus en plus fréquente de souches fongiques et bactériennes résistantes aux antimicrobiens existants sur le marché, contribue de façon sensible à amplifier la gravité des infections fongiques et bactériennes (cutanées et profondes), d'où la nécessité de développer des nouvelles molécules à visée thérapeutique. Dans cette optique, les plantes, source principale des drogues utilisées en médecine traditionnelle, représentent une alternative intéressante. Cassytha filiformis L. (Lauraceae) et Harungana madagascariensis Lam. Ex Poir. (Hypericaceae) sont deux espèces de plantes largem
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18

Турчин, Олена Сергіївна. "Розробка складу біонанокомпозитних плівок з використанням нанотрубок поліфункціонального призначення". Магістерська робота, Київський національний університет технологій та дизайну, 2021. https://er.knutd.edu.ua/handle/123456789/19238.

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Дипломну магістерську роботу присвячено розробці складу біонанокомпозитних плівок з використанням нанотрубок поліфункціонального призначення. Робота виконувалась на базі Інституту газу НАН України та на базі Київського національного університету технологій та дизайну. За результатами проведеної роботи з розробки складу біонанокомпозитних плівок з використанням нанотрубок було використано ліпосоми галлоїзиту та фосфатидилхоліну для розробки нанокомпозитних плівок желатину та казеїну. В ході роботи були обрані ліпосоми Фосфоліпону з 1,0 мг/мл нізину для включення в нанокомпозитні плівки, що міст
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19

Ferrari, Federico. "Synthesis of Metal-Binding Ligand-Containing Copolymers, Nanoparticles and Blends." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/19186/.

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In this thesis we developed three copper-containing systems. Copper shows intriguing abilities in photocatalysis, however, one of the major limitations of many copper complexes is that photochemical properties might be quenched in solution caused by π-interactions between solvent and solute, due to Jahn-Teller distortion in the excited state. As such, we herein seek to synthesise copper heteroleptic complexes that will subsequently be nanoprecipitated with a polymer. This will allow the polymer to encase the complex and prevent the solvent-induced quenching. Subsequently, the preparation of
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Penott-Chang, Evis Karina [Verfasser], and Axel [Akademischer Betreuer] Müller. "Amphiphilic Diblock Copolymers: Study of Interpolyelectrolyte Complexation in Organic Media and Nanoencapsulation of Melatonin / Evis Karina Penott-Chang. Betreuer: Axel Müller." Bayreuth : Universitätsbibliothek Bayreuth, 2011. http://d-nb.info/1015875300/34.

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Rodríguez, Bonilla María Pilar. "Molecular nanoencapsulation of stilbenes by cyclodextrins : study of biochemical, chromatographic and antioxidant applications= Nanoencapsulación molecular de estilbenos por ciclodextrinas: aplicaciones bioquímicas, cromatográficas y antioxidantes." Doctoral thesis, Universidad de Murcia, 2015. http://hdl.handle.net/10803/363919.

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INTRODUCCIÓN Y OBJETIVOS En los últimos años ha cobrado gran fuerza la aparición de los alimentos funcionales, entendiéndose como tales aquellos que le confieren al consumidor un beneficio para la salud más allá de sus propiedades puramente nutritivas. Uno de los grupos de alimentos funcionales que más cuota de mercado está obteniendo es el de los enriquecidos en sustancias bioactivas con un alto valor biológico. En esta tesis doctoral se propone la investigación necesaria para el diseño de alimentos funcionales enriquecidos en diversos tipos de estilbenos, moléculas que han demostrado poseer
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Assis, Renato Queiroz. "Filmes biodegradáveis com adição de licopeno ou β-caroteno livres e nanoencapsulados". reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/157535.

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Filmes biodegradáveis são uma alternativa ao uso de embalagens não biodegradáveis, relacionado ao aumento do uso deste material, impacto e descarte inadequado. Para produção de filmes diversos polímeros podem ser utilizados, em que o amido apresenta boas características e propriedades para obtenção. A adição de antioxidantes naturais nanoencapsulados, como carotenoides, pode auxiliar no desenvolvimento de filmes biodegradáveis com atividade antioxidante, com maior estabilidade e solubilidade destes compostos. Assim, filmes biodegradáveis ativos foram obtidos a partir do amido de mandioca com a
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Kannappan, Vinodh. "Investigation of the anticancer activity and molecular mechanisms of Disulfiram in Glioblastoma Multiforme." Thesis, University of Wolverhampton, 2015. http://hdl.handle.net/2436/600922.

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Glioblastoma Multiforme (GBM) is the most common lethal brain tumour associated with dismal survival rate. GBM is considered to be an incurable malignancy as these tumours evade all intricate attempts of therapy and no contemporary chemotherapeutic regimen is effective. Although the existence of cancer stem cells (CSCs) is still debatable, it is widely accepted that GBM has a small population of cells expressing CSC markers (~1%) that are highly resistant to chemo-radiation therapy. Recent evidence indicates that hypoxia induces cancer stem cell (CSC) phenotypes via epithelial-to-mesenchymal t
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Vasconcelos, Juliana de Almeida Pachioni. "Desenvolvimento de vesículas poliméricas de poli(etileno glicol)-b-poli(ε-caprolactona) (PEG-PCL) para veiculação de L-asparaginase." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/9/9135/tde-26072018-154155/.

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A L-Asparaginase (ASNase) é um importante agente quimioterapêutico utilizado para o tratamento da leucemia linfoblástica aguda (ALL) há mais de 40 anos. No entanto, devido à origem biológica da ASNase, enzima produzida por Escherichia coli, problemas como a imunogenicidade e baixa meia vida-plasmática devem ser considerados. Com o objetivo de minimizar essas desvantagens, várias ASNases homólogas bem como formulações de ASNase de E. coli foram investigadas. Nenhuma das formulações desenvolvidas, entretanto, foi capaz de resolver definitivamente esses problemas associados à sua origem. Nesse se
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BOBADILLA, C. A. FUENMAYOR. "NANOFIBERS: TAILOR-MADE APPLICATIONS FOR THE FOOD AND BEVERAGE INDUSTRY." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/239305.

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Attualmente, l’industria alimentare, per meglio rispondere alle attese dei consumatori, diversifica l’offerta con nuovi prodotti alimentari, risultato della continua ricerca e dell’innovazione tecnologica. L’applicazione di nuovi processi di produzione e l’impiego di materiali innovativi, hanno aumentato la varietà di alimenti disponibili e apportato dei miglioramenti rivelandosi molto promettenti per la futura produzione alimentare. In particolare, le nanotecnologie forniscono materiali quali nanoparticelle, nanoemulsioni, membrane porose, ecc., capaci di migliorare alcune delle principali o
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Aguiar, NÃgela Martins Oliveira. "ObtenÃÃo, caracterizaÃÃo e avaliaÃÃo da estabilidade de extrato do urucum nanoencapsulado em goma do cajueiro." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9910.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>As exigÃncias dos consumidores por uma alimentaÃÃo mais saudÃvel sÃo cada vez maiores, o que tem levado a indÃstria a investir de forma mais persistente no uso de produtos naturais. Um dos segmentos de investimento de destacada importÃncia, à o de substÃncias naturais que atuem como pigmentos, em substituiÃÃo aos corantes artificiais. Devido à alta instabilidade destas substÃncias, diversas pesquisas tÃm buscado determinar condiÃÃes favorÃveis para seu uso. Dentre as substÃncias estudadas tem-se a bixina, um pigmento natural, ca
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Silva, Larissa Morais Ribeiro da. "Compostos bioativos de polpa e subprodutos de frutas tropicais: quantificação, atividade antimicrobiana e encapsulamento." reponame:Repositório Institucional da UFC, 2014. http://www.repositorio.ufc.br/handle/riufc/18645.

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SILVA, Larissa Morais Ribeiro da. Compostos bioativos de polpa e subprodutos de frutas tropicais: quantificação, atividade antimicrobiana e encapsulamento. 2014. 108 f. Tese (Doutorado em tecnologia de alimentos)- Universidade Federal do Ceará, Fortaleza-CE, 2014.<br>Submitted by Elineudson Ribeiro (elineudsonr@gmail.com) on 2016-07-07T19:26:11Z No. of bitstreams: 1 2014_tese_lmrsilva.pdf: 2283546 bytes, checksum: 64374433ae09a06ec47f9593fad6d41e (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-07-21T20:26:58Z (GMT) No. of bitstreams: 1 2014_tese_lmr
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Kitamura, Rodrigo Ossamu Saga. "Estudo fitoquímico biomonitorado em Picramnia bahiensis e Thyrsodium schomburgkianum inseticidas, fungicidas e microencapsulação." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/6269.

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Made available in DSpace on 2016-06-02T20:34:44Z (GMT). No. of bitstreams: 1 5260.pdf: 14825689 bytes, checksum: b6506c8cf1982938a8e81b800ba1089e (MD5) Previous issue date: 2013-03-22<br>Universidade Federal de Minas Gerais<br>The leaf-cutting ants of the genera Atta and Acromyrmex are considered between the most important plagues in agriculture, grassland and reforestation program, due the great amount of leaves cut which the plants are submitted. The factors such as natural resources abundance as food source, scantiness of natural enemies and competitions among others species, promote the
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Bovi, Graziele Grossi. "Óleo de buriti (Mauritia flexuosa L.) nanoemulsionado: produção por método de baixa energia, caracterização físico-química das dispersões e incorporação em bebida isotônica." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/74/74132/tde-02022016-102410/.

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O óleo de buriti (Mauritia flexuosa L.) é o óleo vegetal mais rico em &beta;-caroteno encontrado na biodiversidade brasileira, além de possuir tocoferol e ácido graxo. Apesar do alto valor nutritivo, não é amplamente cultivado e seu processamento comercial é realizado em pequena escala. Sua encapsulação e posterior aplicação em produto alimentício representa uma alternativa para o aumento de seu consumo uma vez que nesta forma pode ser incorporado em produtos alimentares de base aquosa. Este estudo objetivou a produção, caracterização e avaliação da estabilidade de nanoemulsões encapsulando ól
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Herculano, Emanuele Duarte. "Nanoencapsulated Eucalyptus staigeriana essential oil for use as a food preservative." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=12132.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>In this study, the Eucalyptus staigeriana essential oil (ESO) was nanoencapsulated and determined the bactericidal effect of its active principle against two strains of pathogenic mircrorganisms, as a preliminary study for use in food preservation. The process occurred by forming a nanoemulsion and spray-drying, using the cashew gum (CG) as encapsulating material. The nanoparticles were characterized by analysis of particle size distribution, zeta potential, absorption spectroscopy in the infrared Fourier transform spect
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Aguiar, Nágela Martins Oliveira. "Obtenção, caracterização e avaliação da estabilidade de extrato do urucum nanoencapsulado em goma do cajueiro." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/17850.

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AGUIAR, Nágela Martins Oliveira Aguiar. Obtenção, caracterização e avaliação da estabilidade de extrato do urucum nanoencapsulado em goma do cajueiro. 2013. 78 f. : Dissertação (mestrado) - Universidade Federal do Ceará, Centro de Ciências Agrária, Departamento de Tecnologia de Alimentos, Fortaleza-CE, 2013<br>Submitted by Nádja Goes (nmoraissoares@gmail.com) on 2016-06-22T12:53:13Z No. of bitstreams: 1 2013_dis_nmoaguiar.pdf: 1157765 bytes, checksum: 9241d55016c121a7950f5ea9673b4b29 (MD5)<br>Approved for entry into archive by Nádja Goes (nmoraissoares@gmail.com) on 2016-06-22T12:53:29Z (GMT)
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Herculano, Emanuele Duarte. "Óleo essencial de Eucalyptus staigeriana nanoencapsulado para utilização como conservante em alimentos." reponame:Repositório Institucional da UFC, 2014. http://www.repositorio.ufc.br/handle/riufc/17379.

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HERCULANO. Emanuele Duarte. Óleo essencial de Eucalyptus staigeriana nanoencapsulado para utilização como conservante em alimentos. 2014. 86 f. : Dissertação (mestrado) - Universidade Federal do Ceará, centro de Ciências Agrárias, Programa de Pós-Graduação em Tecnologia de Alimentos, Fortaleza-CE, 2014<br>Submitted by Nádja Goes (nmoraissoares@gmail.com) on 2016-06-02T15:23:10Z No. of bitstreams: 1 2014_dis_edherculano.pdf: 2524611 bytes, checksum: a2bde63e81c86e10551edb1c7e551872 (MD5)<br>Approved for entry into archive by Nádja Goes (nmoraissoares@gmail.com) on 2016-06-02T15:24:28Z (GMT) No.
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Quintas, João Pedro Vitorino. "Nanoencapsulation of new compounds with potentioal anti-leishmanial activity." Master's thesis, 2016. http://hdl.handle.net/10451/28372.

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Tese de mestrado, Química Farmacêutica e Terapêutica, Universidade de Lisboa, Faculdade de Farmácia, 2016<br>Infectious diseases caused by viruses, parasites and bacteria are currently the second cause of mortality worldwide. One of these parasites is Leishmania sp., the protozoa responsible for leishmaniasis, which is highly susceptible to oxidative stress where trypanothione reductase is an enzyme that plays a crucial role in the antioxidant defense. Endoperoxide compounds such as tetraoxanes are known to be reductively activated by iron(II)–heme to form carbon-centered radicals that will cr
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Fernandes, Ana Rita Venceslau. "Enhancing the solubility of ibuprofen using biopolymers-based nanoencapsulation." Master's thesis, 2016. http://hdl.handle.net/10316/36512.

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Dissertação de mestrado em Tecnologias do Medicamento, apresentada à Faculdade de Farmácia da Universidade de Coimbra<br>The clinical use of poorly water-soluble drugs has become a big challenge in pharmaceutical development due to the compromised bioavailability of the drugs in vivo. Nanocrystals have been proposed as a formulation strategy to improve the dissolution properties of these drugs. The reduction of the particle size down to the nano-sized range has dramatically changed the physicochemical properties of drugs. Drug nanocrystals show particle sizes varying from 100 nm to 400 nm
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Wingert, Philip Alan. "Nanoencapsulation of luminol-hematin-H2O2 chemiluminescence in calcium phosphate nanoshells." 2006. http://etd.nd.edu/ETD-db/theses/available/etd-07182006-135720/.

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Thesis (Ph. D.)--University of Notre Dame, 2006.<br>Thesis directed by Agnes E. Ostafin for the Department of Chemical and Biomolecular Engineering. "July 2006." Includes bibliographical references (leaves 202-209).
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Haratifar, Sanaz. "Nanoencapsulation of Tea Catechins in Casein Micelles: Effects on Processing and Biological Functionalities." Thesis, 2012. http://hdl.handle.net/10214/4871.

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This thesis focuses on the interactions between milk proteins (caseins) and tea catechins and the consequences of the interactions on the renneting properties and digestion of casein micelles as well as on the biological functionality of the mixture, as measured using intestinal cell models. The binding of epigallocatechin-gallate (EGCG) to casein micelles was quantified using HPLC and fluorescence quenching, and it was shown that a substantial amount of EGCG can be incorporated in the casein micelles. At concentrations < 2.5 mg/ml milk, most of the EGCG added to milk was associated with the
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Nuruzzaman, Md. "Nanoencapsulated pesticide: insights of pesticide loading to enhance the sustainability of nanocarriers." Thesis, 2018. http://hdl.handle.net/1959.13/1385113.

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Research Doctorate - Doctor of Philosophy (PhD)<br>The application of nanotechnology in pesticide delivery is relatively new but has created many opportunities in reducing the losses of pesticides to the environment and ensuring their safe application. Of the various potential applications of nanotechnology, the nanoencapsulation process for pesticide delivery is one of the promising fields of current research. The focus of ongoing research is on the development of nanoencapsulated pesticide formulations that have slow releasing properties with enhanced solubility, permeability, and stability.
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Erdinc, Burak I. "MICRO/NANOENCAPSULATION OF PROTEINS WITHIN ALGINATE/CHITOSAN MATRIX BY SPRAY DRYING." Thesis, 2007. http://hdl.handle.net/1974/898.

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Currently, therapeutic proteins and peptides are delivered subcutaneously, as they are readily denatured in the acidic, protease rich environment of the stomach or gastrointestinal track and low bioavailability results from poor intestinal absorption through the paracellular route. Encapsulation of therapeutic peptides and proteins into polymeric micro- and nano- particle systems has been proposed as a possible strategy to overcome limitations to oral protein administration. Furthermore, it was shown that nanoparticles having diameters less than 5µm are able to be taken up by the M cells of P
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Pitti, Caballero Javier Ernesto. "Nanoencapsulation d’un agent synergisant chimique, la deltaméthrine pour potentialiser l’effet d’un insecticide, l’indoxacarbe contre les insectes nuisibles." Thesis, 2019. http://www.theses.fr/2019ANGE0005/document.

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L’utilisation non raisonnée d’insecticides a des conséquences sur l’environnement et la santé humaine mais aussi sur le développement de résistances chez les insectes nuisibles. Dans ce contexte, ce travail de thèse porte sur le développement d'une technique de nanoencapsulation d'un agent synergisant chimique, la deltaméthrine (pyréthrinoide), associé un pro-insecticide l’indoxacarbe (oxadiazine). Sur la base d’études in vitro sur cellules neurosecrétrices de blattes (Periplaneta americana), une action synergique entre la deltaméthrine et le DCJW (métabolite actif de l’indoxacarbe) a été démo
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Zhong, Wei Heng. "Études de la dispersion et de l'encapsulation des nanotubes de carbone en milieu aqueux." Mémoire, 2013. http://www.archipel.uqam.ca/5598/1/M12772.pdf.

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Depuis leur découverte, les nanotubes de carbone (CNT) ont connu de nombreux succès en raison de leurs performances mécaniques, électriques et thermiques exceptionnelles. L'exploitation de ces propriétés requiert néanmoins de pouvoir isoler les CNT, de les manipuler et de les localiser au sein d'un matériau d'architecture plus ou moins complexe. Pour cela, il est souvent nécessaire de disperser les CNT en raison de leur très grande insolubilité dans tout solvant. De nombreuses stratégies de dispersion reposent sur la stabilisation des CNT par des tensioactifs. Cependant, très peu d'études vise
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Pereira, Irina Patrícia Brito. "Evaluation of the Nanoencapsulation Effects on the Anti-proliferative Activity of Monoterpenes using Human Skin Cell Models." Master's thesis, 2018. http://hdl.handle.net/10348/8391.

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In the last few decades considerable attention by the pharmaceutical field has been paid to the incorporation of nanotechnology in the production of new drug delivery systems (DDS). In the turn of the millennium several research groups centered their attention in the proficient features of lipid nanoparticles (L-NPs). The reduced particle size, large surface area, biocompatible and biodegradable nature, high payload, possibility of controlled release of the active pharmaceutical ingredient (API) and the facility of large scale production are some of the appealing advantages of L-NPs. Moreover,
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VAKARELOVA, Martina. "MICROENCAPSULATION OF BIOACTIVE MOLECULES FROM SPIRULINA PLATENSIS AND HAEMATOCOCCUS PLUVIALIS." Doctoral thesis, 2017. http://hdl.handle.net/11562/964971.

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Nowadays, there is a trend towards a healthier way of living as well as a growing awareness by consumers what benefits for the health certain ingredients have in maintaining it. Preventing diseases through diet is a unique opportunity to use new functional foods. The development and achievement of functional foods requires technologies for incorporating of these investigated health promoting ingredients into food without reducing their bioavailability or functionality. A very interesting example of new functional foods is microalgae. Our laboratory is investigating the special properties of S
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Thomas, Midhun Ben. "Therapeutic Applications of Biodegradable Chitosan Based Polyelectrolyte Nanocapsules." Thesis, 2014. http://etd.iisc.ac.in/handle/2005/3023.

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The past few years have witnessed significant work being directed towards drug delivery systems with layer-by layer (LbL) technique prominently featured as one of the most sought after approach. However, majority of the studies were focused on the fabrication of microcapsules which produced numerous drawbacks resulting in reduced applicability. This has spurred research into nanocapsules which has proved to overcome most of the drawbacks that plagued microcapsules by being able to evade the reticulo-endothelial system, exhibit enhanced permeability and retention in tumours etc. The capsules fa
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Thomas, Midhun Ben. "Therapeutic Applications of Biodegradable Chitosan Based Polyelectrolyte Nanocapsules." Thesis, 2014. http://hdl.handle.net/2005/3023.

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The past few years have witnessed significant work being directed towards drug delivery systems with layer-by layer (LbL) technique prominently featured as one of the most sought after approach. However, majority of the studies were focused on the fabrication of microcapsules which produced numerous drawbacks resulting in reduced applicability. This has spurred research into nanocapsules which has proved to overcome most of the drawbacks that plagued microcapsules by being able to evade the reticulo-endothelial system, exhibit enhanced permeability and retention in tumours etc. The capsules fa
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