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1

Gorbounov, Valeri, Petr Kuban, Purnendu K. Dasgupta, and Henryk Temkin. "A Nanoinjector for Microanalysis." Analytical Chemistry 75, no. 15 (August 2003): 3919–23. http://dx.doi.org/10.1021/ac034342+.

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2

Chen, X., A. Kis, A. Zettl, and C. R. Bertozzi. "A cell nanoinjector based on carbon nanotubes." Proceedings of the National Academy of Sciences 104, no. 20 (May 7, 2007): 8218–22. http://dx.doi.org/10.1073/pnas.0700567104.

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3

Iizuka, Eiji, Takao Tsuda, Motonori Munesue, and Shinichi Samizo. "Nanoinjector for Capillary Electrophoresis and Capillary Electrochromatography." Analytical Chemistry 75, no. 15 (August 2003): 3929–33. http://dx.doi.org/10.1021/ac020778y.

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4

Aten, Quentin T., Brian D. Jensen, Sandra H. Burnett, and Larry L. Howell. "A self-reconfiguring metamorphic nanoinjector for injection into mouse zygotes." Review of Scientific Instruments 85, no. 5 (May 2014): 055005. http://dx.doi.org/10.1063/1.4872077.

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5

Assunção, Nilson A., Ernesto S. Nakayasu, Sirlei Daffre, and Emanuel Carrilho. "Development of nanoinjector devices for electrospray ionization - tandem mass spectrometry (ESI-MSn)." Journal of the Brazilian Chemical Society 23, no. 9 (September 2012): 1762–66. http://dx.doi.org/10.1590/s0103-50532012005000036.

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6

Yoo, Seung Min, Mijeong Kang, Taejoon Kang, Dong Min Kim, Sang Yup Lee, and Bongsoo Kim. "Electrotriggered, Spatioselective, Quantitative Gene Delivery into a Single Cell Nucleus by Au Nanowire Nanoinjector." Nano Letters 13, no. 6 (May 6, 2013): 2431–35. http://dx.doi.org/10.1021/nl4003393.

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7

Yoo, Seung Min, and Sang Yup Lee. "Electro-triggered, spatioselective, quantitative gene delivery into a single cell nucleus by Au nanowire nanoinjector." New Biotechnology 31 (July 2014): S173—S174. http://dx.doi.org/10.1016/j.nbt.2014.05.891.

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8

Lee, Jooran, Sunyoung Choi, Seon Joo Bae, Seok Min Yoon, Joon Sig Choi, and Minjoong Yoon. "Visible light-sensitive APTES-bound ZnO nanowire toward a potent nanoinjector sensing biomolecules in a living cell." Nanoscale 5, no. 21 (2013): 10275. http://dx.doi.org/10.1039/c3nr03042c.

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9

Teng, Wei, Changill Ban, and Jong Hoon Hahn. "Formation of lipid bilayer membrane in a poly(dimethylsiloxane) microchip integrated with a stacked polycarbonate membrane support and an on-site nanoinjector." Biomicrofluidics 9, no. 2 (March 2015): 024120. http://dx.doi.org/10.1063/1.4919066.

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10

Conceição, Ellen Paula Santos da, Christopher J. Madden, and Shaun F. Morrison. "Glycinergic inhibition of BAT sympathetic premotor neurons in rostral raphe pallidus." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 312, no. 6 (June 1, 2017): R919—R926. http://dx.doi.org/10.1152/ajpregu.00551.2016.

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The rostral raphe pallidus (rRPa) contains sympathetic premotor neurons controlling thermogenesis in brown adipose tissue (BAT). We sought to determine whether a tonic activation of glycineA receptors (GlyAR) in the rRPa contributes to the inhibitory regulation of BAT sympathetic nerve activity (SNA) and of cardiovascular parameters in anesthetized rats. Nanoinjection of the GlyAR antagonist, strychnine (STR), into the rRPa of intact rats increased BAT SNA (peak: +495%), BAT temperature (TBAT, +1.1°C), expired CO2, (+0.4%), core body temperature (TCORE, +0.2°C), mean arterial pressure (MAP, +4 mmHg), and heart rate (HR, +57 beats/min). STR into rRPa in rats with a postdorsomedial hypothalamus transection produced similar increases in BAT thermogenic and cardiovascular parameters. Glycine nanoinjection into the rRPa evoked a potent inhibition of the cooling-evoked increases in BAT SNA (nadir: −74%), TBAT (−0.2°C), TCORE (−0.2°C), expired CO2 (−0.2%), MAP (−8 mmHg), and HR (−22 beats/min) but had no effect on the increases in these variables evoked by STR nanoinjection into rRPa. Nanoinjection of GABA into the rRPa inhibited the STR-evoked BAT SNA (nadir: −86%) and reduced the expired CO2 (−0.4%). Blockade of glutamate receptors in rRPa reduced the STR-evoked increases in BAT SNA (nadir: −61%), TBAT (−0.5°C), expired CO2 (−0.3%), MAP (−9 mmHg), and HR (−33 beats/min). We conclude that a tonically active glycinergic input to the rRPa contributes to the inhibitory regulation of the discharge of BAT sympathetic premotor neurons and of BAT thermogenesis and energy expenditure.
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11

Yun, Chang-Koo, Jung Wook Hwang, Tae Joon Kwak, Woo-Jin Chang, Sungjae Ha, Kyuboem Han, Sanghyun Lee, and Yong-Soo Choi. "Nanoinjection system for precise direct delivery of biomolecules into single cells." Lab on a Chip 19, no. 4 (2019): 580–88. http://dx.doi.org/10.1039/c8lc00709h.

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12

Ang Wei, Chunxiang Xu, X. W. Sun, Wei Huang, and Guo-Qiang Lo. "Field Emission From Hydrothermally Grown ZnO Nanoinjectors." Journal of Display Technology 4, no. 1 (March 2008): 9–12. http://dx.doi.org/10.1109/jdt.2007.901569.

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13

Oh, Hwa Jin, and Young Seok Song. "Precise nanoinjection molding through local film heating system." RSC Advances 5, no. 121 (2015): 99797–805. http://dx.doi.org/10.1039/c5ra20206j.

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14

Yang, Xiaxi, Wei Lei, Xiaobing Zhang, Ke Qu, and Jin Zhang. "Synthesis and efficient field emission of ZnO nanoinjectors." Physica E: Low-dimensional Systems and Nanostructures 41, no. 9 (September 2009): 1661–64. http://dx.doi.org/10.1016/j.physe.2009.05.020.

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15

Wilson, Aubrey M., Quentin T. Aten, Nathan C. Toone, Justin L. Black, Brian D. Jensen, Susan Tamowski, Larry L. Howell, and Sandra H. Burnett. "Transgene delivery via intracellular electroporetic nanoinjection." Transgenic Research 22, no. 5 (March 27, 2013): 993–1002. http://dx.doi.org/10.1007/s11248-013-9706-7.

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16

Wang Ma-Hua, Zhu Han-Qing, and Zhu Guang-Ping. "Field emission phenomena of hydro-thermally grown ZnO nanoinjectors." Acta Physica Sinica 60, no. 7 (2011): 077305. http://dx.doi.org/10.7498/aps.60.077305.

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17

Kim, Hyungjun, Hanmin Jang, Bongjoong Kim, Min Ku Kim, Dae Seung Wie, Heung Soo Lee, Dong Rip Kim, and Chi Hwan Lee. "Flexible elastomer patch with vertical silicon nanoneedles for intracellular and intratissue nanoinjection of biomolecules." Science Advances 4, no. 11 (November 2018): eaau6972. http://dx.doi.org/10.1126/sciadv.aau6972.

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Vertically ordered arrays of silicon nanoneedles (Si NNs), due to their nanoscale dimension and low cytotoxicity, could enable minimally invasive nanoinjection of biomolecules into living biological systems such as cells and tissues. Although production of these Si NNs on a bulk Si wafer has been achieved through standard nanofabrication technology, there exists a large mismatch at the interface between the rigid, flat, and opaque Si wafer and soft, curvilinear, and optically transparent biological systems. Here, we report a unique methodology that is capable of constructing vertically ordered Si NNs on a thin layer of elastomer patch to flexibly and transparently interface with biological systems. The resulting outcome provides important capabilities to form a mechanically elastic interface between Si NNs and biological systems, and simultaneously enables direct imaging of their real-time interactions under the transparent condition. We demonstrate its utility in intracellular, intradermal, and intramuscular nanoinjection of biomolecules into various kinds of biological cells and tissues at their length scales.
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18

Stracke, Frank, Iris Rieman, and Karsten König. "Optical nanoinjection of macromolecules into vital cells." Journal of Photochemistry and Photobiology B: Biology 81, no. 3 (December 2005): 136–42. http://dx.doi.org/10.1016/j.jphotobiol.2005.07.006.

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19

Yun, Juanli, Xiaowei Zheng, Peng Xu, Xu Zheng, Jingyue Xu, Chen Cao, Yusi Fu, et al. "Interfacial Nanoinjection‐Based Nanoliter Single‐Cell Analysis." Small 16, no. 9 (September 29, 2019): 1903739. http://dx.doi.org/10.1002/smll.201903739.

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20

Rust, M. J., and C. H. Ahn. "Nanoparticle Assemblies on Nanoinjection-Molded Polymer Templates." IEEE Transactions on Nanotechnology 9, no. 1 (January 2010): 93–98. http://dx.doi.org/10.1109/tnano.2009.2026644.

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21

Rust, Michael J., Jaephil Do, Se Hwan Lee, and Chong H. Ahn. "Nanoinjection Lithography for Submicrometer Electrodes on Polymer Substrates." IEEE Transactions On Nanotechnology 6, no. 4 (July 2007): 460–64. http://dx.doi.org/10.1109/tnano.2007.900507.

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22

Aten, Quentin T., Brian D. Jensen, Susan Tamowski, Aubrey M. Wilson, Larry L. Howell, and Sandra H. Burnett. "Nanoinjection: pronuclear DNA delivery using a charged lance." Transgenic Research 21, no. 6 (March 14, 2012): 1279–90. http://dx.doi.org/10.1007/s11248-012-9610-6.

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23

Wallace, E. Jayne, and Mark S. P. Sansom. "Blocking of Carbon Nanotube Based Nanoinjectors by Lipids: A Simulation Study." Nano Letters 8, no. 9 (September 10, 2008): 2751–56. http://dx.doi.org/10.1021/nl801217f.

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24

Luo, Jie, Deming Wang, Wenqiang Guo, and Hong Cao. "Anesthesia Effect of Propofol Nanoinjection Combined with Nerve Block." Nanoscience and Nanotechnology Letters 12, no. 4 (April 1, 2020): 512–17. http://dx.doi.org/10.1166/nnl.2020.3130.

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Anesthesia for upper limb surgery is commonly used in clinical practice. At present, the traditional method uses anatomical localization for nerve block, which can result incomplete local block and reduced anesthetic effect. Instead, ultrasound-guided nerve block can help clinicians intuitively grasp structure of patient tissues and provide a real-time display of needle penetration. Propofol is the most commonly used intravenous anesthetic in the world, but its use is still limited. In order to improve the limitations of this drug, a propofol nanoemulsion was developed and used in combination with a lower brachial plexus block. In this study, 100 patients were randomly divided into two groups, 50 in each group. The propofol nanoinjection for nerve block was used in the experimental group and ketamine was used in the control group. The quality of the operation, respiratory inhibition/asphyxia, recovery time, OPS score, agitation score, and complications were compared between the two groups. There was no significant difference in blood loss between the two groups (P > 0 05). The experimental results showed that the lower brachial plexus block and propofol nanoemulsion provided a better analgesic effect than ketamine and propofol nanoemulsion in the operation.
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25

Xing, Yan-Fei, Chuan-Lu Yang, Yong-Fang Mo, Mei-Shan Wang, and Xiao-Guang Ma. "Spontaneous nanoinjection with carbon nanotubes: a molecular dynamics simulation study." J. Mater. Chem. B 2, no. 7 (2014): 859–67. http://dx.doi.org/10.1039/c3tb21468k.

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26

Xia, Lang Yan, Kun Hou Huang, and J. Peter Rosenfeld. "Behavioral and trigeminal neuronal effects of rat brainstem-nanoinjected opiates." Physiology & Behavior 52, no. 1 (July 1992): 65–73. http://dx.doi.org/10.1016/0031-9384(92)90434-4.

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27

Chen, Fengming, Sifeng Mao, Hulie Zeng, Shuhua Xue, Jianmin Yang, Hizuru Nakajima, Jin-Ming Lin, and Katsumi Uchiyama. "Inkjet Nanoinjection for High-Thoughput Chemiluminescence Immunoassay on Multicapillary Glass Plate." Analytical Chemistry 85, no. 15 (July 26, 2013): 7413–18. http://dx.doi.org/10.1021/ac4013336.

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28

Memis, Omer Gokalp, John Kohoutek, Wei Wu, Ryan M. Gelfand, and Hooman Mohseni. "Signal-to-noise performance of a short-wave infrared nanoinjection imager." Optics Letters 35, no. 16 (August 6, 2010): 2699. http://dx.doi.org/10.1364/ol.35.002699.

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29

David, Regis A., Brian D. Jensen, Justin L. Black, Sandra H. Burnett, and Larry L. Howell. "Study of design parameters affecting the motion of DNA for nanoinjection." Journal of Micromechanics and Microengineering 22, no. 5 (March 29, 2012): 055006. http://dx.doi.org/10.1088/0960-1317/22/5/055006.

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30

Cao, Wei-Hua, Christopher J. Madden, and Shaun F. Morrison. "Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299, no. 1 (July 2010): R277—R290. http://dx.doi.org/10.1152/ajpregu.00039.2010.

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Neurons in the ventrolateral medulla (VLM) and in the nucleus tractus solitarius (NTS) play important roles in the regulation of cardiovascular and other autonomic functions. In the present study, we demonstrate an inhibition of brown adipose tissue (BAT) thermogenesis evoked by activation of neurons in the VLM, as well as by neurons in the intermediate NTS, of chloralose/urethane-anesthetized, artificially ventilated rats. Activation of neurons in either rostral VLM or caudal VLM with N-methyl-d-aspartate (12 nmol) reversed the cold-evoked increase in BAT sympathetic nerve activity (SNA), BAT temperature, and end-expired CO2. Disinhibition of neurons in either VLM or NTS with the GABAA receptor antagonist, bicuculline (30 pmol), reversed the increases in BAT SNA, BAT temperature, and end-expired CO2 that were elicited 1) by cold defense; 2) during the febrile model of nanoinjection of prostaglandin E2 into the medial preoptic area; 3) by activation of neurons in the dorsomedial hypothalamus or in the rostral raphe pallidus (rRPa); or 4) by the μ-opioid receptor agonist fentanyl. Combined, but not separate, inhibitions of neurons in the VLM and in the NTS, with the GABAA receptor agonist, muscimol (120 pmol/site), produced increases in BAT SNA, BAT temperature, and expired CO2, which were reversed by nanoinjection of glycine (30 nmol) into the rRPa. These findings suggest that VLM and NTS contain neurons whose activation inhibits BAT thermogenesis, that these neurons receive GABAergic inputs that are active under these experimental conditions, and that neurons in both sites contribute to the tonic inhibition of sympathetic premotor neuronal activity in the rRPa that maintains a low level of BAT thermogenesis in normothermic conditions.
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31

Mohammed, Mazher, Christopher J. Madden, Michael C. Andresen, and Shaun F. Morrison. "Activation of TRPV1 in nucleus tractus solitarius reduces brown adipose tissue thermogenesis, arterial pressure, and heart rate." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315, no. 1 (July 1, 2018): R134—R143. http://dx.doi.org/10.1152/ajpregu.00049.2018.

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The sympathetic nerve activity (SNA) to brown adipose tissue (BAT) regulates BAT thermogenesis to defend body temperature in cold environments or to produce fever during immune responses. The vagus nerve contains afferents that inhibit the BAT SNA and BAT thermogenesis evoked by skin cooling. We sought to determine whether activation of transient receptor potential vanilloid 1 (TRPV1) channels in the nucleus tractus solitarius (NTS), which are prominently expressed in unmyelinated vagal afferents, would affect cold-evoked BAT thermogenesis, cardiovascular parameters, or their vagal afferent-evoked responses. In urethane-chloralose-anesthetized rats, during skin cooling, nanoinjection of the TRPV1-agonist resiniferatoxin in NTS decreased BAT SNA (from 695 ± 195% of baseline during cooling to 103 ± 8% of baseline after resiniferatoxin), BAT temperature (−0.8 ± 0.1°C), expired CO2 (−0.3 ± 0.04%), mean arterial pressure (MAP; −20 ± 5 mmHg), and heart rate (−44 ± 11 beats/min). Pretreatment of NTS with the TRPV1 antagonist capsazepine prevented these resiniferatoxin-mediated effects. Intravenous injection of the TRPV1 agonist dihydrocapsaicin also decreased all the measured variables (except MAP). Bilateral cervical or subdiaphragmatic vagotomy attenuated the decreases in BAT SNA and thermogenesis evoked by nanoinjection of resiniferatoxin in NTS but did not prevent the decreases in BAT SNA and BAT thermogenesis evoked by intravenous dihydrocapsaicin. We conclude that activation of TRPV1 channels in the NTS of vagus nerve intact rats inhibits BAT SNA and decreases BAT metabolism, blood pressure, and heart rate. In contrast, the inhibition of BAT thermogenesis following systemic administration of dihydrocapsaicin does not require vagal afferent activity, consistent with a nonvagal pathway through which systemic TRPV1 agonists can inhibit BAT thermogenesis.
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32

Madden, C. J. "Glucoprivation in the ventrolateral medulla decreases brown adipose tissue sympathetic nerve activity by decreasing the activity of neurons in raphé pallidus." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 302, no. 2 (January 15, 2012): R224—R232. http://dx.doi.org/10.1152/ajpregu.00449.2011.

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In urethane/α-chloralose anesthetized rats, cold exposure increased brown adipose tissue sympathetic nerve activity (BAT SNA: +699 ± 104% control). Intravenous administration of 2-deoxy-d-glucose (2-DG; 200 mg·ml−1·kg−1) reversed the cold-evoked activation of BAT SNA (nadir: 139 ± 36% of control) and decreased BAT temperature (−1.1 ± 0.2°C), expired CO2 (−0.4 ± 0.1%), and core temperature (−0.5 ± 0.0). Similarly, unilateral nanoinjection of the glucoprivic agent 5-thioglucose (5-TG; 12 μg/100 nl) in the ventrolateral medulla (VLM) completely reversed the cold-evoked increase in BAT SNA (nadir: 104 ± 7% of control), and decreased TBAT (−1.4 ± 0.3°C), expired CO2 (−0.2 ± 0.0%), and heart rate (−35 ± 10 beats/min). The percentage of rostral raphé pallidus (RPa)-projecting neurons in the dorsal hypothalamic area/dorsomedial hypothalamus that expressed Fos in response to cold exposure (ambient temperature: 4–10°C) did not differ between saline (28 ± 6%) and 2-DG (30 ± 5%) pretreated rats, whereas the percentage of spinally projecting neurons in the RPa/raphé magnus that expressed Fos in response to cold exposure was lower in 2-DG- compared with saline-pretreated rats (22 ± 6% vs. 42 ± 5%, respectively). The increases in BAT SNA evoked by nanoinjection of bicuculline in the RPa or by transection of the neuraxis at the pontomedullary border were resistant to inhibition by glucoprivation. These results suggest that neurons within the VLM play a role in the glucoprivic inhibition of BAT SNA and metabolism, that this inhibition requires neural structures rostral to the pontomedullary border, and that this inhibition is mediated by a GABAergic input to the RPa.
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33

Zu, Guangyue, Magdalena Steinmüller, Damla Keskin, Henny C. van der Mei, Olga Mergel, and Patrick van Rijn. "Antimicrobial Nanogels with Nanoinjection Capabilities for Delivery of the Hydrophobic Antibacterial Agent Triclosan." ACS Applied Polymer Materials 2, no. 12 (November 11, 2020): 5779–89. http://dx.doi.org/10.1021/acsapm.0c01031.

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34

Hennig, Simon, Sebastian van de Linde, Martina Lummer, Matthias Simonis, Thomas Huser, and Markus Sauer. "Instant Live-Cell Super-Resolution Imaging of Cellular Structures by Nanoinjection of Fluorescent Probes." Nano Letters 15, no. 2 (January 6, 2015): 1374–81. http://dx.doi.org/10.1021/nl504660t.

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35

Atkins, Gordon, James Yoon, Kristin Lee, Rachel Koo, Kristin Chung, John Zdor, Darley Magno, et al. "Nanoinjection of neurotransmitters into the prothoracic ganglion of female cricket Acheta domesticus changes phonotactic selectivity." Physiological Entomology 45, no. 4 (August 6, 2020): 131–39. http://dx.doi.org/10.1111/phen.12330.

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36

Memis, O. G., J. Kohoutek, Wei Wu, R. M. Gelfand, and H. Mohseni. "A Short-Wave Infrared Nanoinjection Imager With 2500 A/W Responsivity and Low Excess Noise." IEEE Photonics Journal 2, no. 5 (October 2010): 858–64. http://dx.doi.org/10.1109/jphot.2010.2073695.

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37

Chen, Hou-Yu, Chun-Chi Chen, Fu-Kuo Hsueh, Jan-Tsai Liu, Shyi-Long Shy, Cheng-San Wu, Chao-Hsin Chien, Chenming Hu, Chien-Chao Huang, and Fu-Liang Yang. "A Novel Nanoinjection Lithography (NInL) Technology and Its Application for 16-nm Node Device Fabrication." IEEE Transactions on Electron Devices 58, no. 11 (November 2011): 3678–86. http://dx.doi.org/10.1109/ted.2011.2163938.

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38

Park, Hang-Soo, Hyosung Kwon, Jewon Yu, Yeonju Bae, Jae-Yong Park, Kyung-Ah Choi, Yeonho Choi, and Sunghoi Hong. "Precise nanoinjection delivery of plasmid DNA into a single fibroblast for direct conversion of astrocyte." Artificial Cells, Nanomedicine, and Biotechnology 46, sup1 (March 6, 2018): 1114–22. http://dx.doi.org/10.1080/21691401.2018.1446019.

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39

Li, Yabing, Zhihua Han, Xinmei Zheng, Zhiyuan Ma, Hongling Liu, John P. Giesy, Yuwei Xie, and Hongxia Yu. "Comparison of waterborne and in ovo nanoinjection exposures to assess effects of PFOS on zebrafish embryos." Environmental Science and Pollution Research 22, no. 3 (September 4, 2014): 2303–10. http://dx.doi.org/10.1007/s11356-014-3527-y.

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40

Ekman, E., G. Åkerman, L. Balk, and L. Norrgren. "Nanoinjection as a tool to mimic vertical transmission of Flavobacterium psychrophilum in rainbow trout Oncorhynchus mykiss." Diseases of Aquatic Organisms 55 (2003): 93–99. http://dx.doi.org/10.3354/dao055093.

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41

Xie, Hui, Hao Zhang, Jianmin Song, Xianghe Meng, Junyuan Geng, and Lining Sun. "Living Cell Manipulation and In Situ Nanoinjection Based on Frequency Shift Feedback Using Cantilevered Micropipette Probes." IEEE Transactions on Automation Science and Engineering 17, no. 1 (January 2020): 142–50. http://dx.doi.org/10.1109/tase.2019.2904281.

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42

Nassef, Mohamed, Sang Gyoon Kim, Masanori Seki, Ik Joon Kang, Takeshi Hano, Yohei Shimasaki, and Yuji Oshima. "In ovo nanoinjection of triclosan, diclofenac and carbamazepine affects embryonic development of medaka fish (Oryzias latipes)." Chemosphere 79, no. 9 (May 2010): 966–73. http://dx.doi.org/10.1016/j.chemosphere.2010.02.002.

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43

CHEN, Kun, Naoto IWASAKI, Xuchun QIU, Hai XU, Yuki TAKAI, Kosuke TASHIRO, Yohei SHIMASAKI, and Yuji OSHIMA. "Adipogenesis of Perfluorooctanesulfonate (PFOS) on Japanese Medaka (Oryzias Latipes) Embryo Using Ovo–nanoinjection–mRNA Seq Analysis." Journal of the Faculty of Agriculture, Kyushu University 65, no. 2 (September 2020): 295–303. http://dx.doi.org/10.5109/4103894.

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44

Memis, Omer Gokalp, Alex Katsnelson, Hooman Mohseni, Minjun Yan, Shuang Zhang, Tim Hossain, Niu Jin, and Ilesanmi Adesida. "On the Source of Jitter in a Room-Temperature Nanoinjection Photon Detector at 1.55 $\mu \hbox{m}$." IEEE Electron Device Letters 29, no. 8 (August 2008): 867–69. http://dx.doi.org/10.1109/led.2008.2001123.

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45

Amaral, Nathalia Oda, Lara Marques Naves, Marcos Luiz Ferreira-Neto, André Henrique Freiria-Oliveira, Eduardo Colombari, Daniel Alves Rosa, Angela Adamski da Silva Reis, Danielle Ianzer, Carlos Henrique Xavier, and Gustavo Rodrigues Pedrino. "Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/496121.

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Changes in plasma osmolarity, through central and peripheral osmoreceptors, activate the median preoptic nucleus (MnPO) that modulates autonomic and neuroendocrine adjustments. The present study sought to determine the participation of MnPO in the cardiovascular recovery induced by hypertonic saline infusion (HSI) in rats submitted to hemorrhagic shock. The recordings of mean arterial pressure (MAP) and renal vascular conductance (RVC) were carried out on male Wistar rats (250–300 g). Hemorrhagic shock was induced by blood withdrawal over 20 min until the MAP values of approximately 60 mmHg were attained. The nanoinjection (100 nL) ofGABAAagonist (Muscimol 4 mM; experimental group (EXP)) or isotonic saline (NaCl 150 mM; control (CONT)) into MnPO was performed 2 min prior to intravenous overload of sodium through HSI (3 M NaCl, 1.8 mL/kg, b.wt.). Hemorrhagic shock reduced the MAP in control (62±1.1 mmHg) and EXP (61±0.4 mmHg) equipotently. The inhibition of MnPO impaired MAP (CONT:104±4.2versus EXP:60±6.2 mmHg) and RVC (CONT:6.4±11.4versus EXP:-53.5±10.0) recovery 10 min after HSI. The overall results in this study demonstrated, for the first time, that the MnPO plays an essential role in the HSI induced resuscitation during hypovolemic hemorrhagic shock.
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46

Ishaq, Rasha, Gun Åkerman, Carina Näf, Lennart Balk, Cecilia Bandh, and Dag Broman. "ORGANIC POLLUTANT CHARACTERIZATION AND TOXICITY TESTING OF SETTLING PARTICULATE MATTER BY NANOINJECTION IN SEA TROUT (SALMO TRUTTA) EGGS." Environmental Toxicology and Chemistry 18, no. 3 (1999): 533. http://dx.doi.org/10.1897/1551-5028(1999)018<0533:opcatt>2.3.co;2.

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Ishaq, Rasha, Gun Åkerman, Carina Näf, Lennart Balk, Cecilia Bandh, and Dag Broman. "Organic pollutant characterization and toxicity testing of settling particulate matter by nanoinjection in sea trout (Salmo trutta) eggs." Environmental Toxicology and Chemistry 18, no. 3 (March 1999): 533–43. http://dx.doi.org/10.1002/etc.5620180323.

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48

Ekman, E., G. Åkerman, L. Balk, and L. Norrgren. "Impact of PCB on resistance to Flavobacterium psychrophilum after experimental infection of rainbow trout Oncorhynchus mykiss eggs by nanoinjection." Diseases of Aquatic Organisms 60 (2004): 31–39. http://dx.doi.org/10.3354/dao060031.

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49

Shi, Zhigang, Alyssa Bonillas, and Virginia L. Brooks. "The Effects of Pregnancy on the Sympathoexcitatory and Pressor Responses to Nanoinjection of Angiotensin II into the Arcuate Nucleus." FASEB Journal 34, S1 (April 2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.02521.

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50

Hano, Takeshi, Yuji Oshima, Masato Kinoshita, Minoru Tanaka, Yuko Wakamatsu, Kenjiro Ozato, Mohamed Nassef, Yohei Shimasaki, and Tsuneo Honjo. "In ovo nanoinjection of nonylphenol affects embryonic development of a transgenic see-through medaka (Oryzias latipes), olvas-GFP/STII-YI strain." Chemosphere 77, no. 11 (December 2009): 1594–99. http://dx.doi.org/10.1016/j.chemosphere.2009.09.036.

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