Relevant bibliographies by topics / Nanomagnetism - Small Molecular Organic Ligands

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  2. Dissertations / Theses

Academic literature on the topic 'Nanomagnetism - Small Molecular Organic Ligands'

Author: Grafiati
Published: 7 September 2023

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Journal articles on the topic "Nanomagnetism - Small Molecular Organic Ligands"

1

Milanesi, Eva, Paola Costantini, Alberto Gambalunga, et al. "The Mitochondrial Effects of Small Organic Ligands of BCL-2." Journal of Biological Chemistry 281, no. 15 (2006): 10066–72. http://dx.doi.org/10.1074/jbc.m513708200.

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2

Nilsson, K. Peter R. "Small organic probes as amyloid specific ligands - Past and recent molecular scaffolds." FEBS Letters 583, no. 16 (2009): 2593–99. http://dx.doi.org/10.1016/j.febslet.2009.04.016.

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3

Reiner, Thomas, Sarah Earley, Anna Turetsky, and Ralph Weissleder. "Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells." ChemBioChem 11, no. 17 (2010): 2374–77. http://dx.doi.org/10.1002/cbic.201000477.

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4

Wijtmans, Maikel, Dennis Verzijl, Rob Leurs, Iwan J. P. de Esch, and Martine J Smit. "Towards Small-Molecule CXCR3 Ligands with Clinical Potential." ChemMedChem 3, no. 6 (2008): 861–72. http://dx.doi.org/10.1002/cmdc.200700365.

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5

Blalock, J. E. "On the evolution of ligands: did peptides functionally precede metals and small organic molecules?" Cellular and Molecular Life Sciences (CMLS) 55, no. 4 (1999): 513–18. http://dx.doi.org/10.1007/s000180050309.

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Scodeller, Pablo, and Eliana K. Asciutto. "Targeting Tumors Using Peptides." Molecules 25, no. 4 (2020): 808. http://dx.doi.org/10.3390/molecules25040808.

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To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure of solid tumors, the penetration of higher Mw compounds is unfavored and being small thus becomes an advantage. This review covers a wide range of peptidic ligands—linear, cyclic, macrocyclic and cyclotidic peptides—to target tumors: We describe the main tools to identify peptides experimentally, such as phage display, and the possible chemical modifications to enhance the
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7

Kim, Hyeon Jin, Mi Suk Jeong, and Se Bok Jang. "Molecular Characteristics of RAGE and Advances in Small-Molecule Inhibitors." International Journal of Molecular Sciences 22, no. 13 (2021): 6904. http://dx.doi.org/10.3390/ijms22136904.

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Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage-associated molecular pattern molecules), such as AGEs, HMGB1, and S100/calgranulins, and as an innate immune sensor, can recognize microbial PAMPs (pathogen-associated molecular pattern molecules), including bacterial LPS, bacterial DNA, and viral and parasitic proteins. RAGE and its ligands stimulate the activations of diverse pathways, such as p38MAPK, ERK1/2, Cdc42/Rac, and JNK, and trigger cascades of diverse signaling eve
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8

Tassinari, Martina, Alberto Lena, Elena Butovskaya, et al. "A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety." Molecules 23, no. 8 (2018): 1874. http://dx.doi.org/10.3390/molecules23081874.

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G-quadruplex (G4) nucleic acid structures have been reported to be involved in several human pathologies, including cancer, neurodegenerative disorders and infectious diseases; however, G4 targeting compounds still need implementation in terms of drug-like properties and selectivity in order to reach the clinical use. So far, G4 ligands have been mainly identified through high-throughput screening methods or design of molecules with pre-set features. Here, we describe the development of new heterocyclic ligands through a fragment-based drug discovery (FBDD) approach. The ligands were designed
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9

Gómez-Santacana, Xavier, Sabrina M. de Munnik, Tamara A. M. Mocking, et al. "A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light." Beilstein Journal of Organic Chemistry 15 (October 23, 2019): 2509–23. http://dx.doi.org/10.3762/bjoc.15.244.

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We report a detailed structure–activity relationship for the scaffold of VUF16216, a compound we have previously communicated as a small-molecule efficacy photoswitch for the peptidergic chemokine GPCR CXCR3. A series of photoswitchable azobenzene ligands was prepared through various synthetic strategies and multistep syntheses. Photochemical and pharmacological properties were used to guide the design iterations. Investigations of positional and substituent effects reveal that halogen substituents on the ortho-position of the outer ring are preferred for conferring partial agonism on the cis
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10

Porter, John, Andrew Payne, Ian Whitcombe, et al. "Atropisomeric small molecule Bcl-2 ligands: Determination of bioactive conformation." Bioorganic & Medicinal Chemistry Letters 19, no. 6 (2009): 1767–72. http://dx.doi.org/10.1016/j.bmcl.2009.01.071.

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Dissertations / Theses on the topic "Nanomagnetism - Small Molecular Organic Ligands"

1

Soules, Régis. "Proprietes cooperatives de complexes polymetalliques des ligands squarate et thiosquarate." Toulouse 3, 1987. http://www.theses.fr/1987TOU30178.

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Etude de l'emploi d'un coordinat assembleur qui puisse par coordination avec le centre metallique utilise (metaux de transition du groupe viii) aboutir a un agencement a une dimension des motifs moleculaires par empilement d'entites monomeres ou par formation de chaines. Par utilisation du coordinat squarate sous ses formes oxygenees et soufrees, obtention d'un certain nombre de complexes de pt, pd, ni et cu repondant aux criteres fixes. Etude des structures de ces composes, de leurs proprietes physiques et de la relation structure-propriete. La nature du coordinat comme le caractere specifiqu
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