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Dissertations / Theses on the topic 'Nanoparticulate System'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Salvage, Jonathan Peter. "A novel phosphorylcholine-based nanoparticulate drug delivery system." Thesis, University of Brighton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499068.

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Phosphorylcholine (PC) based materials have been shown to have increased biocompatibility when compared to more established bio-implantable materials. This has been attributed to the ability of PC to mimic the cell lipid bilayer membrane, resulting in reduced protein adhesion and cellular interaction / activation. PC research has previously focused on the areas of contact lens formulation and medical device coating. This project sought to harness the biomimetic properties of PC to develop novel systems for drug delivery, with the emphasis being focused on microparticulate drug delivery.

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2

Yaa, Asantewaa. "Development of a chitosan based glucose responsive nanoparticulate insulin delivery system." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14204/.

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Research into responsive polymeric insulin delivery systems for the management of diabetes mellitus is gaining increasing interest due to the rise in the incidence rate and the burden of daily multiple subcutaneous insulin injections that needs to be endured by the patient. The present study attempted to formulate a nanoparticulate glucose responsive insulin delivery system from a natural polymer chitosan, using a safe glucose sensor, phenyl boronic acid (PBA), which is known to interact with glucose. In the present project, a new method for the production of chitosan tripolyphosphate (TPP) na

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Alkhader, Enas Ali. "Curcumin containing chitosan-pectinate nanoparticulate drug delivery system for colon cancer treatment." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51898/.

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Curcumin, the active constituent of the rhizome Curcuma longa has been extensively studied as an anticancer agent for various types of tumours. However, its efficacy as an anticancer agent is constrained due to poor absorption, rapid metabolism, degradation in acidic media and consequently, low oral bioavailability. In the present study, we aim to formulate a curcumin-containing mucoadhesive nanoparticulate delivery system that offers protection to curcumin from the degradative effects of the upper digestive tract system but capable of releasing the payload in the colon for the localised treat

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4

Walters, Adam Alexander. "The development and evaluation of a nanoparticulate antigen delivery system for vaccination of cattle." Thesis, University of Surrey, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600038.

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Conventional subunit vaccine regimes can be modified in order to stimulate strong immune responses resulting in memory cell formation. An adjuvant system that has gained increased attention in recent years is the use of particulate antigen delivery. Particulate systems have a number of advantages over conventional approaches since they are believed to be taken up preferentially by dendritic cells (DC) where they prolong the release of antigen resulting in enhanced T cell stimulation. Furthermore, they offer a versatile system that allows for targeted delivery of antigen and adjuvant to the sam

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5

Huda, Naz Hasan. "Development of a novel nanoparticulate carrier system for enhancement of bioactive molecule delivery into the brain." Thesis, Curtin University, 2017. http://hdl.handle.net/20.500.11937/54102.

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The development of a biocompatible dual ligand PEGylated poly(D,L-lactide-co-glycolide) nanoparticulate drug delivery system to enhance delivery into the brain. Nanoparticulate formulations containing the drug rivastigmine had physicochemical characteristics ideal for targeting the brain and negligible cytotoxicity. Cell uptake and transport were superior to the drug solution or nanoparticles without the ligand targeting technology. This dual ligand NP drug delivery system is a potential platform technology for brain delivery for a range of therapeutic outcomes.

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6

Haidar, Ziyad. "A hybrid core-shell rhOP-1 nanoparticulate delivery system for enhanced new bone regeneration in distraction osteogenesis." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86713.

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Distraction osteogenesis (DO) is a prevalent surgical technique for the correction of congenital orthopaedic deformities and craniofacial developmental conditions. Yet, clinical benefits continue to be limited by a number of complications mainly as a result of the protracted treatment time during which the fixator has to be kept in situ until the newly-formed bone in the distracted zone consolidates (or hardens), thus exacerbating significant medical, psychological and socio-economical problems on patients, their families and caregivers. On the other hand, protein therapy particularly with the

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7

Pawar, Shilpa. "The design and evaluation of a targeted nanoparticulate drug delivery system for the treatment of brain cancer." Thesis, University of Central Lancashire, 2018. http://clok.uclan.ac.uk/25463/.

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8

Keating, Siobhan. "Nanoparticulate delivery systems for 5-fluorouracil." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343028.

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9

Govender, Thirumala. "Enhancing drug incorporation into nanoparticulate systems." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299551.

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10

Udo-Chijioke, Onyinyechi. "Aquasomes : multilayered nanoparticular drug delivery systems." Thesis, Aston University, 2016. http://publications.aston.ac.uk/33399/.

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Nanoparticulate delivery systems have been widely used in recent decades, available in a wide variety of structures, for targeted drug delivery. They provide controlled and prolonged release for drugs, peptides and biopharmaceuticals. Ceramic nanoparticles are one of the various nanocarriers, which have been employed in local targeted delivery, most commonly in the area of orthopaedic drug delivery to enhance treatment therapies. This thesis therefore focused on the development of aquasomes, a ceramic nanoparticulate carrier system, for the delivery of proteins, growth factors and antibiotics

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11

Hall, M. "Design and evaluation of nanoparticulate delivery systems for prodrugs of fluorouracil." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398106.

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12

Männl, Ulrich Philipp. "Electronic properties and microstructure of nanoparticulate silicon systems for diode applications." Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/12978.

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Includes bibliographical references.<br>In printed electronics the use of semiconducting silicon nanoparticles allows more than the simple printing of conductive materials. It gives the possibility of fabricating robust and inexpensive, active components. This work presents the design, fabrication, and characterization of Schottky barrier diodes using silicon nanoparticulate composites. Within this work it could be shown, that silicon nanoparticles produced by high energy milling can be used to replace the pigment in water-based graphic inks, which on curing have unique semiconducting properti

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13

Sharma, Ankur. "Development of nanoparticulate drug delivery systems for anti-metastatic Ran GTPase therapeutics." Thesis, Ulster University, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725342.

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14

Oswald, Mira [Verfasser], and Achim [Akademischer Betreuer] Göpferich. "Targeted CNS Delivery via Nanoparticulate Drug Delivery Systems / Mira Oswald ; Betreuer: Achim Göpferich." Regensburg : Universitätsbibliothek Regensburg, 2017. http://d-nb.info/1139170708/34.

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15

Oster, Christine. "Microparticular and nanoparticular DNA delivery systems as adjuvants for DNA immunization." [S.l.] : [s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0493/.

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16

Lin, Yue. "Effect of nanoparticulate incorporation on processability, chemistry and thermal properties of high temperature resin systems." Thesis, Loughborough University, 2012. https://dspace.lboro.ac.uk/2134/11759.

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Processability, curing dynamics, network formation, and thermal stability of cyanate ester resin (CY) nanocomposites with triSilanolphenyl polyhedral oligomeric silsesquioxane (POSS), natural montmorillonite clay (Na+), MT2EtOH (methyl, tallow, bis-2-hydroxyethyl, ternary ammonium) modified clay (30B), 2M2HT (dimethyl, dihydrogenatedtallow, quaternary ammonium) modified clay (20A), carbon nanotubes (CNTs) were studied by means of differential scanning calorimetry (DSC), modulated temperature differential scanning calorimetry (MTDSC), X-ray diffraction (XRD), field emission gun scanning electro

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Luechau, Frank. "Process considerations for the recovery of bio-nanoparticulates in polymer-salt aqueous two-phase systems." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289385.

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18

Günday, Türeli Nazende [Verfasser], and Marc [Akademischer Betreuer] Schneider. "Nanoparticulate drug delivery systems for pseudomonas aeruginosa infected lungs in cytic fibrosis / Nazende Günday Türeli ; Betreuer: Marc Schneider." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://d-nb.info/1161729372/34.

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Günday, Türeli Nazende Verfasser], and Marc [Akademischer Betreuer] [Schneider. "Nanoparticulate drug delivery systems for pseudomonas aeruginosa infected lungs in cytic fibrosis / Nazende Günday Türeli ; Betreuer: Marc Schneider." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:291-scidok-ds-272278.

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20

Marín, Mancebo Sergio. "Synthesis and applications of nanoparticles in biosensing systems." Doctoral thesis, Universitat Autònoma de Barcelona, 2009. http://hdl.handle.net/10803/3300.

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En aquesta tesis s'han realitzat diferents síntesis de nanopartícules com són els quantum dots i les nanopartícules d'or i d'argent amb els seus corresponents coreshells (Au-Ag i Ag-Au). Aquestes nanopartícules s'han caracteritzat per diferents tècniques tant òptiques com especialment les electroquímiques. S'ha realitzat un nou sistema de quantificació electroquímica dels quantum dots sintetitzats pel mètode arrested precipitation, utilitzant elèctrodes serigrafiats i un aparell de detecció portàtil.<br/>Aquests quatum dots han estat utilitzats en un sensors de DNA i amb detecció electroquímic

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21

Passirani, Catherine. "Conception de nouveaux vecteurs nanoparticulaires echappant a la phagocytose par blocage de l'activation du systeme du complement." Paris 11, 1997. http://www.theses.fr/1997PA114849.

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22

Ngece, Rachel Fanelwa. "Nanoparticulate of silver-modified poly (8-anilino-1-naphthalene sulphonic acid) nanobiosensor systems for the determination of Tuberculosis treatment drugs." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8724_1320925367.

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This study firstly reports the development and characterization of PVP-AgNPs, PANSA and PVPAgNPs/ PANSA nanocomposite on gold. AFM and TEM analyses revealed highly electroactive nanocomposites whose morphogy and properties were essential for the immobilization of CYP2E1. Secondly, the development and characterization of Au/PVPAgNPs/ PANSA/CYP2E1, Au/PVP-AgNPs/PANSA/SA-CYP2E1 and Au/PVPAgNPs/ PANSA/EG-CYP2E1 nanobiosensors are reported. AFM studies displayed globular morphologies with large roughness for the enzyme modified electrodes as opposed to those electrodes without enzymes. Finally, the

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23

Memiṣoǧlu, Erem. "Evaluation of amphiphilic β-cyclodextrins modified on the primary face as novel excipients in the preparation of nanoparticulate drug delivery systems". Paris 11, 2002. http://www.theses.fr/2002PA114809.

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24

Huve, Pierre. "Comprendre et éviter la capture des nanoparticules de poly(acidelactique) par le système des phagocytes mononucléaires." Paris 11, 1994. http://www.theses.fr/1994PA114826.

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25

Chiewpattanakul, Paramaporn. "Isolation and structure elucidation of biosurfactant from microorganism and its application model in drug delivery system." Thesis, Vandoeuvre-les-Nancy, INPL, 2010. http://www.theses.fr/2010INPL004N/document.

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Des microorganismes produisant des molécules tensioactives ont été isolés à partir d’échantillons de sols contaminés par des huiles, en provenance des provinces de Songkhla et Chiangmai (Thaïlande) et de Shianghai (Chine). Les différentes souches ont été sélectionnées de façon à obtenir les biosurfactants ayant les meilleures propriétés tensioactives et d’émulsification. Parmi 102 souches isolées, 6 microorganismes produisaient des biosurfactants. La souche SK80 a conduit aux meilleures propriétés tensioactives. Des observations morphologiques macroscopiques et microscopiques ont permis de car

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26

De, Marco Giovanni. "Caracterisation, mecanismes d'action et evaluation de nanoparticules superparamagnetiques injectables par voie iv pour l'i. R. M. Du systeme lymphatique." Angers, 1996. http://www.theses.fr/1996ANGE0504.

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27

Melo, Vitor Hugo Soares de. "Investigação por meio de efeito SERS e SERRS dos sistemas híbridos formados pela interação da 3,6-bi-2-piridil-1,2,4,5-tetrazina e complexos de rutênio com ouro macroscópico e nanoparticulado." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/46/46134/tde-21072010-083127/.

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A síntese e caracterização de sistemas hetero-híbridos gerados a partir da 3,6-bi-2-piridil-1,2,4,5-tetrazina (bptz) e interações com ouro nanoparticulado são abordados nesta tese. O bptz foi estudado por meio de métodos espectroscópicos e teóricos, focalizando principalmente o efeito SERS associado à adsorção em nanopartículas de ouro. O mecanismo de transferência de carga para metais macroscópicos foi transposto para a condição nanoparticulada, envolvendo ligações químicas entre bptz e as nanopartículas. Os complexos estudados possuem fórmula geral [LmRu(µ-bptz)RuLm]Xn, com “L&#8

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28

Soliman, Soliman Mehawed Abdellatif. "From photosensitive glycopolymers to smart drug delivery systems." Thesis, Université de Lorraine, 2014. http://www.theses.fr/2014LORR0147/document.

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Des glycopolymères greffés et dibloc, amphiphiles et photosensibles, à base de poly(acrylate d'o-nitrobenzyle) (PNBA) hydrophobe et photoclivable et de dextrane hydrophile ont été préparés avec succès en utilisant notammennt une réaction d'Huisgen (Cycloaddition Azoture-Alcyne catalysée par le Cuivre (I) - CuAAC chimie click). Dans un premier temps, la polymérisation de l'acrylate d'o-nitrobenzyle a été contrôlée avec succès grâce aux développements récents de la polymérisation radicalaire vivante par transfert d'un seul électron (SET-LRP). Nous avons alors obtenu un PNBA fonctionnalisé à son

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29

Roussel, Michael. "Intégration sur silicium et caractérisation de films minces de polyuréthane nanocomposite pour le développement de micro-actionneurs MEMS électrostrictifs." Thesis, Lyon, INSA, 2012. http://www.theses.fr/2012ISAL0135/document.

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Ce travail de thèse s'inscrit dans le cadre général du développement de micro-actionneurs MEMS, à bas coût et de technologie simple, pour de futures applications dans le domaine de la microfluidique, notamment. La motivation de ce travail est d'évaluer la faisabilité d'un micro-actionneur électrostricitf à base de film mince polymère électroactif nanocomposite. Le polyuréthane, chargé en nanoparticules de carbone ou carbure de fer, encore peu étudié mais aux propriétés électrostrictives prometteuses, est choisi comme matériau à intégrer dans une filière MEMS silicium classique. Le premier chap

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Samarão, Filipa Rosa Lima Barros Afonso. "Novos sistemas terapêuticos para administração nasal de fármacos." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5315.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>A via de administração nasal de fármacos é uma via não invasiva e apresenta um elevado interesse devido às vantagens que possui relativamente a outras vias, tais como: previne o metabolismo hepático, a sua mucosa apresenta uma elevada área disponível para absorção, possui um epitélio fino e altamente vascularizado. Estas caraterísticas permitem obter uma elevada permeabilidade e uma rápida absorção dos fármacos administrados, pri

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Peyrot, Marianne. "Adaptation structurale des bio vecteurs supra moléculaires (BVSM) pour l'incorporation d'un principe actif peptidique en vue de son administration par voie orale." Toulouse, INSA, 1992. http://www.theses.fr/1992ISAT0005.

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L'administration de medicaments par voie orale est un mode privilegie tant par le patient que par le praticien mais elle est souvent inutilisable du fait de la sensibilite de nombreux principes actifs au milieu enzymatique ou a leur non absorption par la muqueuse intestinale. Les bio vecteurs supra moleculaires (bvsm) sont un nouveau systeme de transport de principes actifs, constitue d'un noyau polysaccharidique reticule nanoparticulaire derive en peripherie par une couronne d'acides gras greffes et recouvert d'un feuillet phospholipidique externe. L'objectif de ce travail a ete de mettre au

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Koot, Dwayne Jonathan. "Strategic pre-clinical development of Riminophenazines as resistance circumventing anticancer agents." Thesis, University of Pretoria, 2012. http://hdl.handle.net/2263/24163.

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Cancer is responsible for upward of 13% of human deaths. Contemporary chemotherapy of disseminated cancer is often thwarted by dose limiting systemic toxicity and by multi-drug resistance (MDR). Riminophenazines are a novel class of potential anticancer agents that possess a potent multi-mechanistic antineoplastic action. Apart from their broad action against intrinsic, non-classical resistance, Riminophenazines inhibit the action of Pgp and hypothetically all ABC transporters demonstrating their great utility against classical MDR. Considering that combination chemotherapy is the norm, the vi

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Lajous, Hélène. "Cisplatine : une vieille molécule pour de nouveaux défis. : développement d’une prodrogue macromoléculaire multifonctionnelle applicable au traitement local du glioblastome." Thesis, Angers, 2018. http://www.theses.fr/2018ANGE0046/document.

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Le glioblastome constitue la tumeur primitive maligne la plus fréquente et la plus agressive du système nerveux central, caractérisée par un pronostic sombre. L’infusion locale dans le parenchyme cérébral du cisplatine a présenté des résultats encourageants sur des modèles précliniques. La nanovectorisation permet de concentrer l’efficacité thérapeutique d’agents anticancéreux à leur cible. Leur fonctionnalisation par des unités d’imagerie offre la possibilité de suivre de façon non invasive par imagerie par résonance magnétique (IRM) leur biodistribution au sein du tissu lésé. Dans cette opti

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Aka, Armelle Adjoua Sandrine. "Développement de systèmes d'administration originaux destinés à la prévention de la contamination par le VIH chez la femme." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-01015614.

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Avec près de 30 millions de morts depuis le début de la pandémie, l'infection par le VIH est un véritable fléau à l'échelle mondiale, surtout en Afrique sub-saharienne. Dans ce contexte, disposer d'une formulation microbicide efficace, facile à administrer par la voie vaginale, représenterait un outil de prévention idéal pour lutter contre cette pandémie. Ainsi, la conception rationnelle de telles formulations représente un enjeu majeur de santé publique.Ce travail décrit la recherche de formulations thermogélifiantes et mucoadhésives à base de pluronics et d'hydroxypropyl méthylcellulose (HPM

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Singh, Latavia. "An architecturally-configured nanoparticulate system for targeted treatment of hepatitis B virus infection." Thesis, 2015. http://hdl.handle.net/10539/18542.

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A dissertation submitted to the Faculty of Health Sciences, University of the Witwatersrand, in fulfillment of the requirements for the degree of Master of Pharmacy Johannesburg 2015<br>Viruses boast a highly skilled mode of entry into the cells of all living organisms. This occurs due to the intelligent make-up of these biological systems. A drug delivery system was designed to mimic viruses ordinarily, hence taking advantage of cell entry ease that these viruses parade and ultimately, as a result, ensuring intracellular antiviral transmittal to targeted sites in the body. The Hepatitis B Vi

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Li, Guo-hao, and 李國豪. "Application of Agar Hydrogel Based Nanoparticulate System for Enhancing the Dissolution Rates of Indomethacin." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/52863992325404541830.

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碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>94<br>Abstract The bioavailability of water-insoluble drug is poor. The aim of the present study was to design a suspension composed of numberless nanoparticles to improve the solubility of indomethacin. Hydrogel based nanoparticles encapsulating indomethacin were prepared by using the solid jelly pulverization technique, and then freeze-dry to lyophilized powder. In the freeze-drying process, hydrogel based nanoparticles undergo change of temperature and water content, eventually forming water-insoluble aggregates. The pH value adjusted as well as the cryopr

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Chuang, Cheng-Lin, and 莊政霖. "Development of a smart nanoparticulate drug delivery system for targeting chemotherapy of bone metastasis." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/83y2r9.

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Rafael, Diana Fernandes de Sousa 1987. "Akt2 siRNA-nanoparticulate system as a new tool to restoration of e-cadherin and eradicate tumor metastic phenotype." Doctoral thesis, 2017. http://hdl.handle.net/10451/28893.

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Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmácia, 2017<br>Cancer has currently a major impact in the worldwide health, with breast and colon carcinomas presenting the second and third highest incidence rates, respectively. Despite the important advances in understanding the mechanism of carcinogenesis, disease progression, and development of new and more effective therapies, advanced cancer is still generally an incurable disease. The currently used treatments have improved both the survival and cure rates of patients; however there are so

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Costa, Ana Carolina Ramos. "Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system." Master's thesis, 2017. http://hdl.handle.net/10451/34293.

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Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017<br>This work explores distinct strategies to overcome phenylketonuria (PKU; OMIM 261600), the most common autosomal recessive disorder of amino acid metabolism caused by a deficiency of the hepatic human phenylalanine hydroxylase enzyme (hPAH; EC 1.14.16.1) and for which the available therapies rely mainly in a dietetic restriction. PKU is considered a conformational disease, with loss-of-function, where the normal balance between folding and degradation machineries (proteostasis) is displaced towa

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Villalobos, Hernández Juan Ramón. "Nanoparticulate systems for medical and cosmetical sun protection /." 2007. http://www.gbv.de/dms/bs/toc/53061877x.pdf.

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Gran, Martin Luke. "Metal-polymer nanoparticulate systems for externally-controlled delivery." Thesis, 2010. http://hdl.handle.net/2152/ETD-UT-2010-12-2494.

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Metal-polymer nanocomposites consisting of gold nanorods and temperature-responsive hydrogel nanoparticulates were investigated for use in externally-controlled drug delivery systems. Several different thermo-responsive hydrogels including poly(N-isopropyl acrylamide) (PNIPAAm) and poly(N-isopropryl acrylamide-co-acrylic acid) (P(NIPAAm-co-AA)) nanoparticles were synthesized for these nanocomposites using an aqueous dispersion polymerization method. In addition, nanoparticles of interpenetrating polymer networks (IPN) composed of poly(acrylamide) (PAAm) and poly(acrylic acid) (PAA) were synt

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Rosa, Daniela Maria Barata. "Gold nanoparticulate systems for new anticancer compounds delivery." Master's thesis, 2014. http://hdl.handle.net/10362/13879.

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My master studies have resulted in the following publication: Martins P, Rosa D, Fernandes AR, Baptista PV. 2014. Nanoparticle Drug Delivery Systems: Recent Patents and Applications in Nanomedicine. Recent Patents in Nanomedicine. 3(2):105-118.

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Ganta, Srinivas. "Development and Evaluation of Nanoparticulate Drug Delivery Systems for Anticancer Drugs." 2008. http://hdl.handle.net/2292/3081.

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The main aim of this study was to develop nanoparticulate drug delivery systems for chlorambucil (CHL) and asulacrine (ASL). CHL is a DNA alkylating agent. In an attempt to alter the pharmacokinetics (short half-life, rapid clearance and high volume of distribution) and improve the anticancer activity, CHL was incorporated into a lipid nanosphere (LN) formulation. The LN were composed of soybean oil as the internal oil phase, egg lecithin as the primary emulsifier, cholesterol as the phospholipid layer stabilizer, and water as the external phase. PEG-modified (long circulating) and DOTAP-modif

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Kafantaris, Fotios Christos. "On the reactivity of nanoparticulate elemental sulfur : experimentation and field observations." Diss., 2017. http://hdl.handle.net/1805/14969.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>The reaction between elemental sulfur and sulfide is a lynchpin in the biotic and abiotic cycling of sulfur. This dissertation is focused on the reactivity of elemental sulfur nanoparticles (S8weimarn, S8raffo) among other forms of elemental sulfur (S8aq, S8aq-surfactant, α-S8), and how the variation of their surface area, character and coatings reflect on the analytical, physical-chemical and geochemical processes involving sulfur cycling. A comprehensive electrochemical investigation utilizing mercury-surface electrodes showed th

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Ferreira, Sara Ataíde. "Development of fucoidan/chitosan nanoparticulate systems for protein administration through mucosal routes." Master's thesis, 2012. http://hdl.handle.net/10400.1/3668.

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Dissertação de mest., Engenharia Biológica , Faculdade de Ciências e Tecnologia, Univ. do Algarve, 2012<br>Presently, the administration of therapeutic proteins through non-parenteral routes poses a challenge due to stability problems, mainly attributed to pH and high enzymatic content present in mucosal surfaces. Therefore, the administration of proteins through mucosal routes requires the development of suitable carriers which confer stability and protection against harsh environments of the organism and that further facilitate macromolecule permeation. Polymeric nanoparticles have been prop

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Florindo. "Development of alternative micro and nanoparticulate polymeric systems for mucosal delivery of Streptococcus equi antigens." Doctoral thesis, 2008. http://hdl.handle.net/10451/262.

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Tese de doutoramento em Farmácia (Tecnologia Farmacêutica), apresentada à Universidade de Lisboa através da Faculdade de Farmácia, 2008<br>S. equi is considered the causative agent of strangles, a very contagious disease of the upper respiratory tract of the Equidae. Although S. equi is sensitive to some antibiotics, most of the current treatments are ineffective. During the recovery period, horses develop a protective immune response mostly against the antiphagocytic cell wall-associated M-like protein SeM, which encourages the development of efficient vaccines. The main purpose of this thesi

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Braz, Luís Manuel Lima Verde de. "Synthesis of Locust Bean Gum new derivatives and their application in nanoparticulate drug delivery systems." Doctoral thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/85984.

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Braz, Luís Manuel Lima Verde de. "Synthesis of Locust Bean Gum new derivatives and their application in nanoparticulate drug delivery systems." Tese, 2016. https://repositorio-aberto.up.pt/handle/10216/85984.

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"Development of visible light photolytic systems for hydrogen generation employing platinum square planar complexes or nanoparticulate nickel as catalysts." Tulane University, 2011.

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The current world demands for energy are continuously increasing. In order to minimize CO2 emission and become independent of foreign oil, it is a crucial time to develop renewable energy sources. Virtually all (non-nuclear) fuel consumption involves oxidation processes. In the search for solar fuels, there is a need to find good reducing agents utilizing sunlight as the energy source. The sun is the most abundant renewable source of energy on earth, delivering a vast amount of energy every day. It is our goal to use sunlight to reduce water to molecular hydrogen, which can then be employed to

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Oster, Christine [Verfasser]. "Microparticular and nanoparticular DNA delivery systems as adjuvants for DNA immunization / vorgelegt von Christine Oster." 2004. http://d-nb.info/973037911/34.

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