Academic literature on the topic 'Nanostructured Lipid Carrier (NLC)'

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Journal articles on the topic "Nanostructured Lipid Carrier (NLC)"

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Patil, Deepak, Seema Pattewar, Sarvesh Palival, Gargi Patil, and Swapnil Sharma. "Nanostructured lipid carriers: A platform to lipophilic drug for oral bioavailability enhancement." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 758–64. http://dx.doi.org/10.22270/jddt.v9i3-s.2750.

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Lipid based drug delivery system such as Solid lipid nanoparticle (SLN) and Nanostructured lipid carriers (NLC) are among the most promising drug delivery system used in many industries such as food, pharmaceuticals and cosmetics industries. Over the last few years, new constituents of lipids have developed and investigated for enhancement of bioavailability. The present manuscript is an attempt on solving the concerned uncertainty with efficacious peroral administration of hydrophobic drugs through fabricating new lipid formulations, NLC. NLC, the second-generation lipid carrier is usually co
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RAJ, BRITO. "Investigating the influence of lipids on Nano-structured lipid carrier formulation." Journal of Medical pharmaceutical and allied sciences 12, no. 6 (2023): 6147–54. http://dx.doi.org/10.55522/jmpas.v12i6.5220.

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The study aimed to evaluate the effect of different lipids on the properties of nanostructured lipid carrier (NLC) formulations. The particle size, zeta potential, polydispersity index, entrapment efficiency, and drug release at 24 hours were analyzed for formulations containing various lipid matrices. Among the formulations tested, N3 (Compritol 888 ATO and Softigen) exhibited the most favourable characteristics, including the smallest particle size, highest entrapment efficiency, sustained drug release, and good stability, as indicated by a high zeta potential. Other lipids, such as Witepsol
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Widiyana, Anita Puspa. "Computation Design: Nanostructured Lipid Carrier Formula of Pinostrobin." Jurnal Ilmu Farmasi dan Farmasi Klinik 21, no. 1 (2024): 22. http://dx.doi.org/10.31942/jiffk.v21i1.8378.

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Nano lipid carriers (NLC) function by increasing the solubility and oral bioavailability of hydrophobic drugs. This study was conducted to estimate the solubility of pinostrobin in various types of solid and liquid lipid carriers through computational design and to select the optimal NLC formula with the best candidate lipid carriers. Pinostrobin and all lipid carriers were determined for their interactions with the AutoDockTools program. The values of the free energy binding (ΔG), the inhibition constant (Ki), and the type of interaction visibility were recorded as a result of the molecular d
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Rajshri.R.Dusane, Yogeeta.S.Agrawal Sonia.M.Goyal Kalyani.A.Chaudhari. "A REVIEW ARTICLE ON NANOSTRUCTURED LIPID CARRIERS (NLCS) FOR DRUG DELIVERY AND TARGETING SYSTEM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 9568–77. https://doi.org/10.5281/zenodo.2819849.

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<em>During the past decade, the number of studies describing nanostructured lipid carriers (NLC)-based formulations has been dramatically increased. The raise in NLC exploitation is essentially due to defeated barriers within the technological process of lipid-based nanoparticles&rsquo; formulation and increased knowledge of the underlying mechanisms of transport of NLC via different routes of administration. This review article aims to give an overview on the current state of the art of nanostructured lipid carriers as controlled drug delivery systems for future clinics through novel NLC appl
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Khasanah, Usrifatul, and M. Fatchur Rochman. "STABILITAS NANOSTRUCTURED LIPID CARRIER COENZYME Q10 DENGAN VARIASI WAKTU PENGADUKAN." Jurnal Ilmu Farmasi dan Farmasi Klinik 18, no. 2 (2022): 55. http://dx.doi.org/10.31942/jiffk.v18i2.5958.

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ABSTRACTCoenzyme Q10 (Co-Q10) or Ubiquinone is an antioxidant that is unstable to light and is highly lipophilic causing instability during storage, so a Nanostructured Lipid Carrier (NLC) delivery system is needed that can improve stability. The manufacture of NLC uses the emulsification method by melting two types of lipids, namely solid lipid cetyl palmitate and liquid lipid alpha tocopherol with the help of stirring using a magnetic stirrer. The purpose of this study was to determine the characteristics and stability of NLC Co-Q10 at various stirring times. The results of testing the chara
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Jaswinder, Singh *. "LIPID NANOPARTICULATE DRUG DELIVERY SYSTEMS." Journal of Pharma Research 8, no. 8 (2019): 557–63. https://doi.org/10.5281/zenodo.3374087.

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<strong><em>ABSTRACT</em></strong> <strong><em>C</em></strong><em>olloidal particles of size range between 10 and 1000 nm are known as nanoparticles. Over the last few years, lipid based drug delivery systems such as solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) and lipid drug conjugate (LDC) have become the most promising drug delivery systems. Each preparation of the lipid based nanoparticles has advantages and disadvantages with respect to specific characteristics. The SLN is an excellent drug delivery system and has extensive prospects in the pharmaceutical field. N
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Latifah, Luluk, Esti Hendradi, and Dewi Isadiartuti. "Nanostructured Lipid Carrier (NLC) as a Topical Drug Delivery System : A Review." Journal of Pharmaceutical Sciences and Community 21, no. 2 (2024): 178–89. https://doi.org/10.24071/jpsc.006789.

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Nanostructured Lipid Carrier (NLC) appears as the next generation of lipid nanoparticles which overcomes the weaknesses of Solid Lipid Nanoparticles (SLN). NLC is a delivery system that offers several advantages, such as significantly improved entrapment efficiency, reduced drug expulsion during long-term storage, and increased contact between the drug and the stratum corneum, thereby enhancing drug penetration. The methods used to manufacture NLC have high energy-required such as high-pressure homogenization and high shear homogenization, low energy-required such as microemulsification and ph
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Wang, Jian Min, Yan Li, Hong Xia Wang, et al. "Antioxidative Activity Evaluation of CoQ10-Nanostructured Lipid Carrier." Advanced Materials Research 284-286 (July 2011): 989–92. http://dx.doi.org/10.4028/www.scientific.net/amr.284-286.989.

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The CoQ10-NLC aqueous dispersion has been produced and its antioxidative properties have been explored. Several employed methods such as scavenging effect on DPPH radical and inhibition of hydroxyl radical and superoxide anion generation exhibited CoQ10-NLC aqueous dispersion potent antioxidative property. Antioxidative activity analysis demonstrated that CoQ10- NLC aqueous dispersion formulation expressed antioxidative property.
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Rochman, M. Fatchur, Aditya Darmawan, and Pramudya Wardhana. "Nanostructured Lipid Carriers System Solid Lipid Poloxamer and Stearic Acid with Liquid Lipid Soybean Oil." Jurnal Ilmiah Medicamento 8, no. 1 (2022): 1–7. http://dx.doi.org/10.36733/medicamento.v8i1.3161.

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Nanostructured Lipid Carriers (NLC) are lipid-based carrier system that use a matrix combination in the form of solid and liquid which are stabilized with the addition of surfactant. This NLC was developed to facilitate the dispersion of hydrophobic bioactive compound in a hydrophilic system. This research aims to get the right formulation and can develop stable characterization, using solid lipids Poloxamer and Stearic Acid with liquid lipids Soybeans Oil using surfactant Tween 80 and co-surfactant Propyleneglycol.. The to make the formulation of NLC with a ratio of poloxamer and stearic acid
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Chime, Salome. "Application of Cyperus esculentus oil in the development of sustained release diclofenac sodium-loaded nanostructured lipid carrier." Journal of Current Biomedical Research 2, no. 3, May-June (2022): 145–59. http://dx.doi.org/10.54117/jcbr.v2i3.23.

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The aim of the work was to develop sustained release diclofenac sodium nanostructured lipid carrier (NLC) using tigernut oil (TNO), solid lipids and polyethylene glycol 4000 (PEG 4000) and to evaluate the properties of the formulations. Structured lipids containing tiger nut oil, Softisan®154 and Phospholipon® 90H at varying ratios were prepared by fusion and used as the lipid carrier in formulating the NLC. PEGylated lipid carriers were also employed and the physicochemical properties of these formulations were studied using standard methods including particle size and polydispersity index, e
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Dissertations / Theses on the topic "Nanostructured Lipid Carrier (NLC)"

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Hommoss, Aiman [Verfasser]. "Nanostructured Lipid Carriers (NLC) in dermal and personal care formulations / Aiman Hommoss." Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023465574/34.

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RAVANI, Laura. "FOCUS ON NANOSTRUCTURED LIPID CARRIERS AND MONOOLEIN AQUEOUS DISPERSIONS." Doctoral thesis, Università degli studi di Ferrara, 2012. http://hdl.handle.net/11392/2389252.

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Nowadays, everyone feels the impact of nanotechnology in his life. There is a trend that urges people to revisit many research areas with a nano-view, in order to understand how the same thing can work at nano- level. This phenomenon is revolutionizing pharmaceutical sciences and many drugs are being reformulated for possibilities of delivering as a nanosystem. In recent years, a particular attention has been focused on new generations of lipid nanoparticles such as nanostructured lipid carriers (NLC), a second generation of solid lipid nanoparticles (SLN), and monoolein aqueous dispersi
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Houacine, Chahinez. "Resveratrol nanostructured lipid carrier for targeted delivery to breast cancer." Thesis, University of Central Lancashire, 2018. http://clok.uclan.ac.uk/23956/.

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Background: Breast cancer remains a prominent cause of mortality and morbidity in the female population. Despite advances in terms of novel compounds, exhibiting chemotherapeutic activity successful delivery remains challenging. Particulate-based system such as Nanostructured Lipid Carriers (NLCs) a new generation carrier allow encapsulation of drug and targeting of desired tissue. Resveratrol (RES) is a chemotherapeutic drug limited by its physiochemical properties (i.e. poor solubility and bioavailability), encapsulation into NLCs is potentially viable solution to the aforementioned issues.
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Monteiro, Lis Marie. "Buparvaquone nanostructured lipid carrier development: physicochemical and in vitro leishmanicidal performances." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-06122017-100536/.

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Leishmaniases is a group of diseases caused by parasites of the genus Leishmania. The estimated number of deaths from visceral leishmaniases ranges from 20,000 to 50,000 annually. The most common treatment over the past 60 years has been pentavalent antimonials. Besides the doubtful effectiveness, they present several disadvantages such as the need for parenteral administration, large doses, long treatment, severe toxicity and parasite resistance. Buparvaquone (BPQ), a drug used for veterinary treatment of theileriosis, showed promising activity against Leishmania spp. However, due to its low
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Sousa, Marcelo de 1980. "Preparação de nanopartículas lipídicas sólidas NLS para liberação modificada/prolongada de fármacos antiretrovirais (Nevirapina, Saquinavir e Efavirenz)." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/250356.

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Orientador: Francisco Benedito Teixeira Pessine<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-23T23:52:35Z (GMT). No. of bitstreams: 1 Sousa_Marcelode_D.pdf: 3494030 bytes, checksum: 462ff3b363ece6e2ff2f83e5d1028485 (MD5) Previous issue date: 2013<br>Resumo: Nos dias atuais não há cura e nem vacina para as pessoas portadoras de HIV. A erradicação do vírus não é possível porque a maioria está depositado em órgãos que são de difícil acesso aos fármacos antirretrovirais. Uma alternativa seria direcionar os fármacos à estes ó
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Rocha, Kamilla Amaral David. "Desenvolvimento de formulações contendo voriconazol encapsulado em nanopartículas lipídicas e promotores químicos de absorção para aplicação tópica na unha." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/8190.

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Submitted by Liliane Ferreira (ljuvencia30@gmail.com) on 2018-02-28T14:49:21Z No. of bitstreams: 2 Dissertação - Kamilla Amaral David Rocha - 2015.pdf: 3193387 bytes, checksum: 6cc146ed197535b6a21627e8ffa4891c (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2018-02-28T16:16:32Z (GMT) No. of bitstreams: 2 Dissertação - Kamilla Amaral David Rocha - 2015.pdf: 3193387 bytes, checksum: 6cc146ed197535b6a21627e8ffa4891c (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5
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Matsumoto, Mirian Yoshiko. "Efeitos dos complexos de níquel e platina derivados de base de Schiff no câncer de bexiga urinária não-músculo invasivo." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/155992.

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Submitted by Mirian Yoshiko Matsumoto (mirian_matsumoto@hotmail.com) on 2018-09-13T03:42:01Z No. of bitstreams: 1 Tese de Doutorado BGA Mirian Matsumoto.pdf: 5590776 bytes, checksum: 35a18a86dcfd4a42e7e9c40dbce00a94 (MD5)<br>Approved for entry into archive by ROSANGELA APARECIDA LOBO null (rosangelalobo@btu.unesp.br) on 2018-09-14T16:51:20Z (GMT) No. of bitstreams: 1 matsumoto_my_dr_bot.pdf: 5590776 bytes, checksum: 35a18a86dcfd4a42e7e9c40dbce00a94 (MD5)<br>Made available in DSpace on 2018-09-14T16:51:20Z (GMT). No. of bitstreams: 1 matsumoto_my_dr_bot.pdf: 5590776 bytes, checksum: 35a18a8
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Marcial, Sara Pacelli de Sousa. "Desenvolvimento de nanopart?culas lip?dicas contendo paclitaxel." UFVJM, 2016. http://acervo.ufvjm.edu.br/jspui/handle/1/1128.

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?rea de concentra??o: Ci?ncias farmac?uticas.<br>Data de aprova??o ausente.<br>Disponibiliza??o do conte?do parcial, conforme Termo de Autoriza??o no trabalho.<br>Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2016-12-20T19:20:11Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) sara_pacelli_sousa_marcial_parcial.pdf: 166236 bytes, checksum: c01c4f087337cd82c64b06b90a1cc4dc (MD5)<br>Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-01-17T18:55:36Z (GMT) No. of bitstreams: 2 license_rdf: 0
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Negretto, Carla Maria Uggeri. "TRANSPORTADORES LIPÍDICOS NANOESTRUTURADOS CONTENDO VITAMINA E: VALIDAÇÃO DE MÉTODOS ANALÍTICOS E AVALIAÇÃO IN VITRO DA CAPACIDADE ANTIOXIDANTE." Centro Universitário Franciscano, 2014. http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/522.

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Submitted by MARCIA ROVADOSCHI (marciar@unifra.br) on 2018-08-16T18:33:24Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_CarlaMariaUggeriNegretto.pdf: 1746117 bytes, checksum: 50d675658fbe05428861169424e0b28b (MD5)<br>Made available in DSpace on 2018-08-16T18:33:24Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_CarlaMariaUggeriNegretto.pdf: 1746117 bytes, checksum: 50d675658fbe05428861169424e0b28b (MD5) Previous issue date: 2014-03-28<br>Vitamin E is an important agent i
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Almeida, Ellen Denise Prado. "Desenvolvimento de partículas lipídicas contendo alumínio-cloro ftalocianina para aplicação na terapia fotodinâmica do câncer de pele." Universidade Federal de Sergipe, 2014. https://ri.ufs.br/handle/riufs/3933.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Skin cancer is the malign tumor most common worldwide and nonmelanoma is the kind of cancer most treatable. However, nowadays there is not a ideal treatment of the skin cancer and the surgery is the therapeutic standard for treatment of malign lesion in the skin. Photodynamic therapy (PDT) consists of the administration and accumulation of photosensitizers in target cells, followed by exposure to a light source with appropriate wavelength, resulting in the formation of oxygen reactive species, responsibles for causing damage to c
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Book chapters on the topic "Nanostructured Lipid Carrier (NLC)"

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Müller, Rainer H., Ulrike Alexiev, Pricillia Sinambela, and Cornelia M. Keck. "Nanostructured Lipid Carriers (NLC): The Second Generation of Solid Lipid Nanoparticles." In Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-47862-2_11.

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Joshi, Medha D., Rashmi H. Prabhu, and Vandana B. Patravale. "Fabrication of Nanostructured Lipid Carriers (NLC)-Based Gels from Microemulsion Template for Delivery Through Skin." In Pharmaceutical Nanotechnology. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9516-5_19.

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Kumar, P. Suresh, Maheswara Reddy Mallu, Kalyani Chepuri, Katkojwal Sandhya, Mangala Gunapreethi, and C. D. S. L. N. Tulasi. "Nanostructured lipid carriers (NLCs) for the aqueous-based food preservation." In Antimicrobials for Sustainable Food Storage. CRC Press, 2024. http://dx.doi.org/10.1201/9781003288503-20.

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Shah, Nirmal, Dipti Gohil, and Snehal Patel. "Nanostructured Lipid Carriers (NLCs): A Modern Versatile Drug Delivery Vehicle." In Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6_4.

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Chakraborty, Tapash, Malay K. Das, Lopamudra Dutta, Biswajit Mukherjee, Sanjoy Das, and Anupam Sarma. "Successful Delivery of Zidovudine-Loaded Docosanol Nanostructured Lipid Carriers (Docosanol NLCs) into Rat Brain." In Surface Modification of Nanoparticles for Targeted Drug Delivery. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-06115-9_14.

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Chakraborty, Tapash, Malay K. Das, Lopamudra Dutta, Biswajit Mukherjee, Sanjoy Das, and Anupam Sarma. "Correction to: Successful Delivery of Zidovudine-Loaded Docosanol Nanostructured Lipid Carriers (Docosanol NLCs) into Rat Brain." In Surface Modification of Nanoparticles for Targeted Drug Delivery. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-06115-9_26.

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Verma, Pravin, Gita Sahu, and Ritika Singh. "Development And Evaluation Of Piperine Nanostructured Lipid Carrier Mordant Drug Delivery System." In Computational Optimization, Modeling, and Simulation for Engineering Applications. Apple Academic Press, 2024. http://dx.doi.org/10.1201/9781003454021-1.

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Patel, Naisargee, Rajeev K. Tyagi, and Neeraj K. Garg. "Nanostructured Lipid Carrier-Mediated Methotrexate Delivery Evokes Transcription Factors to Induce Selective Apoptosis in Rheumatoid Arthritis." In NanoBioMaterials. CRC Press, 2018. http://dx.doi.org/10.1201/9781351138666-12.

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"Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for Dermal Delivery." In Percutaneous Absorption. CRC Press, 2005. http://dx.doi.org/10.1201/9780849359033-56.

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Muller, R., E. Souto, and W. Mehnert. "Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for Dermal Delivery." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2005. http://dx.doi.org/10.1201/9780849359033.ch53.

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Conference papers on the topic "Nanostructured Lipid Carrier (NLC)"

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Noor, N. M., Z. I. Abd-Rasid, A. Ishak, N. I. Wan Azelee, A. Abd-Aziz, and R. Hasham. "Proof-of-concept study of virgin coconut oil-nanostructured lipid carrier (VCO-NLC) for hair care applications." In PROCEEDINGS OF THE 6TH INTERNATIONAL CONFERENCE ON COMPUTING AND APPLIED INFORMATICS 2022. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0182901.

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Torres, Joana, José Miguel Pereira, Renata Silva, et al. "Potential of Antioxidant-Loaded Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for the Management of Neurodegenerative Diseases." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13417.

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Khang, Van Chi, Nguyen Phu Thuong Nhan, and Mai Huynh Cang. "Fabrication of nanostructured lipid carriers (NLC) for encapsulation of gac (Momordica cochinchinensis) oil by using homogenization method." In II INTERNATIONAL SCIENTIFIC FORUM ON COMPUTER AND ENERGY SCIENCES (WFCES-II 2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0101285.

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Grasso, R., M. Gulino, A. Scordino, et al. "The delayed luminescence spectroscopy as tool to investigate the cytotoxic effect on human cancer cells of drug-loaded nanostructured lipid carrier." In SPIE Photonics Europe, edited by Jürgen Popp, Valery V. Tuchin, Dennis L. Matthews, and Francesco S. Pavone. SPIE, 2016. http://dx.doi.org/10.1117/12.2227514.

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