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Journal articles on the topic 'Nanotechnology-based drug delivery'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Dasgupta, Ankur. "Nanotechnology based Drug Delivery for Brain Targeting." International Journal for Research in Applied Science and Engineering Technology 12, no. 1 (2024): 328–29. http://dx.doi.org/10.22214/ijraset.2024.57931.

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Abstract: Nanotechnology is an excellent and evolving technology that can be used in the field of healthcare, engineering, environmental science, etc. There is a protective barrier around the brain called the blood brain barrier (BBB) which prevents the entry of larger molecules inside the brain, maintaining brain homeostasis and this poses as a problem because the drugs implemented during any CNS disorder cannot reach the brain. Nanoparticles are solid particles that range from 1-100nm in diameter and are used as a carrier for drug delivery. Nanoparticles are used because of their various cha

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Onkar, Kalokhe* Sameer Bhilare Sangram Bandal Sourav Hagavane Shital Rokde Dr. Kishorotari. "Nanotechnology –Based Drug Delivery System." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 46–55. https://doi.org/10.5281/zenodo.15569146.

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Nanoparticles having a huge potential for use as an effective medicine delivery system. In this post, we discussed recent developments in nanotechnology-based drug delivery. Nanotechnology has gained interest recently as a potential remedy for medical and gene delivery problems. Nanosystems with different compositions and biological properties have been thoroughly studied for the transportation of genes and medicines. Achieving effective drug delivery requires an understanding of how nanomaterials interact with the biological environment, including how they target cell-surface receptors, relea

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Suri, Sarabjeet, Hicham Fenniri, and Baljit Singh. "Nanotechnology-based drug delivery systems." Journal of Occupational Medicine and Toxicology 2, no. 1 (2007): 16. http://dx.doi.org/10.1186/1745-6673-2-16.

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Ravichandran, R. "Nanotechnology-Based Drug Delivery Systems." NanoBiotechnology 5, no. 1-4 (2009): 17–33. http://dx.doi.org/10.1007/s12030-009-9028-2.

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Kuskov, Andrey N., Ekaterina V. Kukovyakina, and Ekaterina N. Krasnoselskaya. "Nanotechnology-Based Drug Delivery Systems." Pharmaceutics 17, no. 7 (2025): 817. https://doi.org/10.3390/pharmaceutics17070817.

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Yang, Xiaosong, Shizhu Chen, Xiao Liu, Miao Yu, and Xiaoguang Liu. "Drug Delivery Based on Nanotechnology for Target Bone Disease." Current Drug Delivery 16, no. 9 (2019): 782–92. http://dx.doi.org/10.2174/1567201816666190917123948.

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Bone diseases are a serious problem in modern human life. With the coming acceleration of global population ageing, this problem will become more and more serious. Due to the specific physiological characteristics and local microenvironment of bone tissue, it is difficult to deliver drugs to the lesion site. Therefore, the traditional orthopedic medicine scheme has the disadvantages of high drug frequency, large dose and relatively strong side effects. How to target deliver drugs to the bone tissue or even target cells is the focus of the development of new drugs. Nano drug delivery system wit

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Kumar, Virender, Nangu Kumar, Manithu Shilsut, and Joginder Kumar. "Nanotechnology- based target drug delivery system." Journal of Pharmaceutical and Biological Sciences 10, no. 2 (2023): 49–52. http://dx.doi.org/10.18231/j.jpbs.2022.010.

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A nanotechnology can be described as the process of manipulating, studying, and manufacturing objects with a nanometer dimension. Through site-specific, targeted delivery of medicines, nanotechnology can benefit the treatment of chronic diseases in humans. Recent nanomedicine discoveries have led to the development of numerous outstanding drugs e.g., chemotherapeutics, biologics, immunotherapeutic, etc. The purpose of this chapter is to describe various nanocarriers that can be used to deliver therapeutic molecules.

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Singh, Ruchita, Charles Brumlik, Mandar Vaidya, and Abhishek Choudhury. "A Patent Review on Nanotechnology-Based Nose-to-Brain Drug Delivery." Recent Patents on Nanotechnology 14, no. 3 (2020): 174–92. http://dx.doi.org/10.2174/1872210514666200508121050.

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Background: Current cerebral drug delivery to the brain and Cerebrospinal Fluid (CSF) is limited by the Blood-Brain Barrier (BBB) or the blood-blood Cerebrospinal Fluid (CSF) barrier. The popular, non-invasive, intranasal delivery provides an exciting route for topical and systemic applications. For example, intranasal drug delivery of Central Nervous System (CNS) drugs can be designed to pass the BBB barrier via the nose-to-brain pathways. Recent nanotechnology research and patenting focus mainly on overcoming typical limitations including bioavailability, transport, BBB penetration, targeted

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Nanjwade, Basavaraj K. "Nanotechnology Based Virosomal Drug Delivery Systems." Journal of Nanotechnology and Materials Science 1, no. 1 (2014): 1–9. http://dx.doi.org/10.15436/2377-1372.14.003.

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10

Jain, K. K. "Nanotechnology-based Drug Delivery for Cancer." Technology in Cancer Research & Treatment 4, no. 4 (2005): 407–16. http://dx.doi.org/10.1177/153303460500400408.

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Nanobiotechnologies have been applied to improve drug delivery and to overcome some of the problems of drug delivery in cancer. These can be classified into many categories that include use of various nanoparticles, nanoencapsulation, targeted delivery to tumors of various organs, and combination with other methods of treatment of cancer such as radiotherapy. Nanoparticles are also used for gene therapy for cancer. Some of the technologies enable combination of diagnostics with therapeutics which will be important for the personalized management of cancer. Some of the limitations of these tech

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Ebube Victor Emeihe, Ejike Innocent Nwankwo, Mojeed Dayo Ajegbile, Janet Aderonke Olaboye, and Chukwudi Cosmos Maha. "Revolutionizing drug delivery systems: Nanotechnology-based approaches for targeted therapy." International Journal of Life Science Research Archive 7, no. 1 (2024): 040–58. http://dx.doi.org/10.53771/ijlsra.2024.7.1.0060.

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Nanotechnology has emerged as a transformative force in drug delivery systems, offering unprecedented precision in targeting diseased cells while minimizing side effects. This paper explores the revolutionary impact of nanotechnology-based approaches on drug delivery, particularly in the context of targeted therapy for various diseases, including cancer, cardiovascular disorders, and infectious diseases. Nanotechnology enables the design of drug delivery systems at the molecular level, allowing for the development of nanoscale carriers that can deliver therapeutic agents directly to specific c

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Mohapatra, Tapas Kumar, Priyanka Behera, Pratibha Patel, and Rajesh Pothal. "Nano based drug delivery systems: Emerging trends and future prospects." International Journal of Pharmaceutical Research and Applications 09, no. 05 (2024): 1198–213. https://doi.org/10.35629/4494-090511981213.

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Drug delivery systems based on nanotechnology have enormous potential to transform medicine by improving therapeutic efficacy, lowering side effects, and facilitating precision medicine. Liposomes, solid lipid nanoparticles, polymeric nanoparticles, and dendrimers are examples of nanocarriers that have shown notable benefits in terms of drug solubility, bioavailability, sitespecific and controlled delivery to diseased cells. By providing controlled and sustained release mechanisms, these systems minimise systemic toxicity and enable optimal dosing schedules. Through ligand functionalisation, r

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Dureja, Harish, and Sunil Khatak. "Recent Advances in Nanotechnology based Tubercular Chemotherapy." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 3 (2015): 2979–94. http://dx.doi.org/10.37285/ijpsn.2015.8.3.4.

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Tuberculosis (TB) is a more prevalent granulomatos bacterial infection, which remains the world’s second most common cause of death due to infections of Mycobacterium tuberculosis (M.Tuberculosis). A number of characteristics of mycobacterium makes there disease chronic and necessitate prolonged treatment. The emergence of multi-drug-resistance (MDR) stains of M.Tuberculosis makes its necessary for the development of effective combinations of either first-line or second-line drugs or discovery of new safe and effective drug molecules and also implements other modalities of treatment. A number

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Jin, Yuxin. "Nanotechnology-Based Targeted Drug Delivery Systems for Cancer Treatment." Theoretical and Natural Science 69, no. 1 (2025): 61–70. https://doi.org/10.54254/2753-8818/2025.19722.

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This study explores the mechanism of nanotechnology-based targeted drug delivery in cancer treatment, particularly focusing on the preparation and application of nanodrugs for specific types of cancer. The article first analyzes the physicochemical properties and drug delivery advantages of common carriers such as liposomes, gold nanoparticles, and polysaccharide nanoparticles. It then discusses the classification, preparation, and application of nanoparticle-based delivery systems and nanoemulsion-based delivery systems. Following this, the drug delivery mechanisms of nanodelivery systems are

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Nandhini Chitikela and Chaitanya B. "Current Advances in Nanotechnology-Based Drug Delivery Systems." Journal of Pharma Insights and Research 3, no. 1 (2025): 327–34. https://doi.org/10.69613/hvaf5254.

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Nanotechnology is a revolutionary trend in pharmaceutical sciences, particularly in drug delivery systems. The usage of nanoscale materials and devices in medicine has revolutionized therapeutic strategies across various diseases, from cancer to cardiovascular disorders. Nanocarrier systems, ranging from 1-100 nanometers, demonstrate remarkable capabilities in enhancing drug solubility, bioavailability, and targeted delivery. These systems include micelles, liposomes, dendrimers, carbon nanotubes, metallic nanoparticles, and quantum dots, each offering unique advantages in drug encapsulation a

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Maurya, Sujata, Rashi Srivastava, Saniya Arfin, et al. "Exploring state-of-the-art advances in targeted nanomedicines for managing acute and chronic inflammatory lung diseases." Nanomedicine 17, no. 30 (2022): 2245–64. http://dx.doi.org/10.2217/nnm-2021-0437.

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Diagnosis and treatment of lung diseases pose serious challenges. Currently, diagnostic as well as therapeutic methods show poor efficacy toward drug-resistant bacterial infections, while chemotherapy causes toxicity and nonspecific delivery of drugs. Advanced treatment methods that cure lung-related diseases, by enabling drug bioavailability via nasal passages during mucosal formation, which interferes with drug penetration to targeted sites, are in demand. Nanotechnology confers several advantages. Currently, different nanoparticles, or their combinations, are being used to enhance targeted

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Misra, Manju, Aashu Gupta, and Kritika Nayak. "Nanotechnology-based Strategies for Ocular Drug Delivery Systems." International Journal of Pharmaceutical Sciences and Nanotechnology 11, no. 3 (2019): 4073–88. http://dx.doi.org/10.37285/ijpsn.2018.11.3.1.

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This review describes current nanotechnology-based delivery systems for ocular targeting. Amongst all the drug delivery systems existing today, ocular drug delivery is one such delivery approach which is having great endeavours due to the challenges faced by it. Many new as well as exciting treatment options have emerged in this field. The major cause behind development of new treatment alternatives in this field are the limitations raised by the conventional approaches. Currently, researchers are working on development of novel nano techniques to overcome these challenges. The major hurdle is

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Luo, Yuanrui, Hongwei Chen, Hua Chen, et al. "Recent Advances in Nanotechnology-Based Strategies for Bone Tuberculosis Management." Pharmaceuticals 17, no. 2 (2024): 170. http://dx.doi.org/10.3390/ph17020170.

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Bone tuberculosis, an extrapulmonary manifestation of tuberculosis, presents unique treatment challenges, including its insidious onset and complex pathology. While advancements in anti-tubercular therapy have been made, the efficacy is often limited by difficulties in achieving targeted drug concentrations and avoiding systemic toxicity. The intricate bone structure and presence of granulomas further impede effective drug delivery. Nano-drug delivery systems have emerged as a promising alternative, offering the enhanced targeting of anti-tubercular drugs. These systems, characterized by their

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Güven, Eylem. "Nanotechnology-based drug delivery systems in orthopedics." Joint Diseases and Related Surgery 32, no. 1 (2021): 267–73. http://dx.doi.org/10.5606/ehc.2021.80360.

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20

Deo, Sapna K., Shanta Dhar, and Sylvia Daunert. "Drug delivery: Challenges and nanotechnology-based solutions." Molecular Aspects of Medicine 83 (February 2022): 101051. http://dx.doi.org/10.1016/j.mam.2021.101051.

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Malaviya, Pooja, Dhaval Shukal, and Abhay R. Vasavada. "Nanotechnology-based Drug Delivery, Metabolism and Toxicity." Current Drug Metabolism 20, no. 14 (2020): 1167–90. http://dx.doi.org/10.2174/1389200221666200103091753.

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Background: Nanoparticles (NPs) are being used extensively owing to their increased surface area, targeted delivery and enhanced retention. NPs have the potential to be used in many disease conditions. Despite widespread use, their toxicity and clinical safety still remain a major concern. Objective: The purpose of this study was to explore the metabolism and toxicological effects of nanotherapeutics. Methods: Comprehensive, time-bound literature search was done covering the period from 2010 till date. The primary focus was on the metabolism of NP including their adsorption, degradation, clear

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22

Kuskov, Andrey N., and Ekaterina V. Kukovyakina. "Nanotechnology-Based Drug Delivery Systems, 2nd Edition." Pharmaceutics 17, no. 1 (2025): 110. https://doi.org/10.3390/pharmaceutics17010110.

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23

Ashtekar, Kiran Sadashiv, Ashish Ashok Monde, Priyanka Nilangekar, Uddhav Bagul, Mayuri Nazirkar, and Chandrakant Kokare. "A review on nanotechnology based ophthalmic drug delivery system." Journal of Drug Delivery and Therapeutics 13, no. 12 (2023): 262–69. http://dx.doi.org/10.22270/jddt.v13i12.6337.

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The field of ophthalmic drug delivery has witnessed significant advancements through the integration of nanotechnology. Despite having numerous conventional dosage forms employed in the ocular drug delivery system the problem of less bioavailability and less retention time is a significant concern. Along with it there are various barriers also involved that affects the drug permeability, solubility due to the lower residence time of the drug on ocular surface. To overcome these problems the nanotechnology approach can be most suitable. All nanocarriers have emerged as a promising career for pr

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Misra, Charu, Manish Gaur, and Laxmi Narayan Gupta. "Nanotechnology: Emerging Platform for Drug Based Delivery System in Cancer." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 744–49. http://dx.doi.org/10.22270/jddt.v9i4.3152.

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In present scenario cancer has become one of the most difficult global healthcare problems, despite of having library of anti-cancer drugs the problem remains the same due to no specificity, burst release, damaging of normal cells and numerous side effects. Nanotechnology the emerging field gained attention as it offers site specific treatment in various tumors with lesser side effect. Nano carriers, a transport module provide platform to circumvent the problems related with the delivery of anticancer drug in drug delivery systems. Nano carriers help to improve the bioavailability and therapeu

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Chivere, Vanessa T., Pierre P. D. Kondiah, Yahya E. Choonara, and Viness Pillay. "Nanotechnology-Based Biopolymeric Oral Delivery Platforms for Advanced Cancer Treatment." Cancers 12, no. 2 (2020): 522. http://dx.doi.org/10.3390/cancers12020522.

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Routes of drug administration and their corresponding physiochemical characteristics play major roles in drug therapeutic efficiency and biological effects. Each route of delivery has favourable aspects and limitations. The oral route of delivery is the most convenient, widely accepted and safe route. However, the oral route of chemotherapeutics to date have displayed high gastric degradation, low aqueous solubility, poor formulation stability and minimum intestinal absorption. Thus, mainstream anti-cancer drugs in current formulations are not suitable as oral chemotherapeutic formulations. Th

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Kagkelaris, Konstantinos, George Panayiotakopoulos, and Constantinos D. Georgakopoulos. "Nanotechnology-based formulations to amplify intraocular bioavailability." Therapeutic Advances in Ophthalmology 14 (January 2022): 251584142211123. http://dx.doi.org/10.1177/25158414221112356.

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Conventional drug delivery formulations, such as eye drops and ointments, are mainly administered by topical instillation. The topical delivery of ophthalmic drugs is a challenging endeavor despite the eye is easily accessible. Unique and complex barriers, serving as protection against extrinsic harmful factors, hamper therapeutic intraocular drug concentrations. Bioavailability for deeper ocular tissues of the anterior segment of the eye is exceptionally low. As the bioavailability of the active substance is the major hurdle to overcome, dosing is increased, so the side effects do. Both provo

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Li, Jingyuan, Hong Xiang, Qian Zhang, and Xiaoqing Miao. "Polysaccharide-Based Transdermal Drug Delivery." Pharmaceuticals 15, no. 5 (2022): 602. http://dx.doi.org/10.3390/ph15050602.

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Materials derived from natural plants and animals have great potential for transdermal drug delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources. Compared with synthetic polymers, polysaccharides have the advantages of non-toxicity and biodegradability, ease of modification, biocompatibility, targeting, and antibacterial properties. Currently, polysaccharide-based transdermal drug delivery vehicles, such as hydrogel, film, microneedle (MN), and tissue scaffolds are being developed. The addition of polysaccharides allows these vehicles to exhibit better-swelli

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Samie, Hany A. Abdel, Mohd Saeed, Syed Mohd Faisal, Mohd Adnan Kausar, and Mohammad A. Kamal. "Recent Findings on Nanotechnology-based Therapeutic Strategies Against Hepatocellular Carcinoma." Current Drug Metabolism 20, no. 4 (2019): 283–91. http://dx.doi.org/10.2174/1389200220666190308134351.

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Background: Nanotechnology-based therapies are emerging as a promising new anticancer approach. Early clinical studies suggest that nanoparticle-based therapeutics can show enhanced efficacy while reducing side effects minimal, owing to targeted delivery and active intracellular uptake. Methods: To overcome the problems of gene and drug delivery, nanotechnology based delivery system gained interest in the last two decades. Encouraging results from Nano formulation based drug delivery systems revealed that these emerging restoratives can efficiently lead to more effective, targeted, selective a

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Epameinondas Georgakopoulou, Vasiliki, Petros Papalexis, and Nikolaos Trakas. "Nanotechnology-based approaches for targeted drug delivery for the treatment of respiratory tract infections." Journal of Biological Methods 11, no. 4 (2024): e99010032. http://dx.doi.org/10.14440/jbm.2024.0065.

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Background: Nanotechnology has emerged as a promising field for the diagnosis, monitoring, and treatment of respiratory tract infections (RTIs). By leveraging the unique properties of nanoscale delivery systems, nanotechnology can significantly enhance the selectivity and efficacy of antimicrobials, thereby reducing off-target effects. Objective: This review explores the development and application of targeted nanosystems in combating viral, bacterial, and fungal RTIs. Nanotechnology-based systems, including biological and non-biological nanoparticles, offer innovative solutions for overcoming

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Sharma, Mayank, Rajesh Sharma, and Dinesh Kumar Jain. "Nanotechnology Based Approaches for Enhancing Oral Bioavailability of Poorly Water Soluble Antihypertensive Drugs." Scientifica 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/8525679.

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Oral administration is the most convenient route among various routes of drug delivery as it offers high patient compliance. However, the poor aqueous solubility and poor enzymatic/metabolic stability of drugs are major limitations in successful oral drug delivery. There are several approaches to improve problems related to hydrophobic drugs. Among various approaches, nanotechnology based drug delivery system has potential to overcome the challenges associated with the oral route of administration. Novel drug delivery systems are available in many areas of medicine. The application of these sy

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Kathole, Khushi S., Pooja Ramdas Hatwar, Ravindra L. Bakal, and Vaishnavi G. Karule. "Nano technology-based drug delivery systems and herbal medicine." Journal of Drug Delivery and Therapeutics 15, no. 3 (2025): 133–41. https://doi.org/10.22270/jddt.v15i3.7017.

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Nanotechnology has revolutionized the field of herbal medicine by enhancing the bioavailability and efficacy of phytoconstituents. This review article discusses the application of nanotechnology in herbal medicine, including the use of nanoparticles, liposomes, and nanoemulsions for targeted drug delivery. The advantages of nanotechnology-based herbal formulations, such as improved solubility, stability, and bioavailability, are highlighted. Additionally, the review discusses the potential of nanotechnology in enhancing the therapeutic efficacy of herbal medicines, including their anti-inflamm

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Alehaidib, Soliman Mohammed, Omar Obaid Alharbi, Maysam Taysir Almegbel, and Ahlam Mohammed Alzahrani. "Drug delivery systems for osteogenic disorders utilizing green nanotechnology." International journal of health sciences 4, S1 (2020): 67–86. http://dx.doi.org/10.53730/ijhs.v4ns1.15037.

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Background: The skeletal system, crucial for structural support, movement, and various metabolic processes, is continually remodeled through the balanced activity of osteoblasts, osteocytes, and osteoclasts. Disruptions in this balance lead to bone disorders, including osteoporosis and osteogenesis imperfecta, necessitating effective therapeutic strategies. Traditional drug delivery systems face challenges such as poor targeting efficiency and systemic toxicity. Aim: This review examines the application of green nanotechnology in developing advanced drug delivery systems for treating osteogeni

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Yoon, Hee-Jae, and Woo-Dong Jang. "Nanotechnology-based photodynamic therapy." Journal of Porphyrins and Phthalocyanines 17, no. 01n02 (2013): 16–26. http://dx.doi.org/10.1142/s108842461230011x.

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According to recent advances in nanotechnology, various nano-sized formulations have been designed for the application in biomedical fields, including diagnosis, drug delivery, and therapeutics. The nanotechnology-based formulations have a great merit in the design of multifunctional platform for the biomedical applications. Therefore, recent trends in nanotechnology are moving onto the combination of nanotechnology and conventional therapeutic. Typically, photodynamic therapy (PDT) is one of promising techniques for the combination with nanotechnology owing to its less invasiveness. In this p

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Liu, Yu-Chi, Molly Tzu-Yu Lin, Anthony Herr Cheun Ng, Tina T. Wong, and Jodhbir S. Mehta. "Nanotechnology for the Treatment of Allergic Conjunctival Diseases." Pharmaceuticals 13, no. 11 (2020): 351. http://dx.doi.org/10.3390/ph13110351.

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Allergic conjunctivitis is one of the most common external eye diseases and the prevalence has been increasing. The mainstay of treatment is topical eye drops. However, low bioavailability, low ocular drug penetration, transient resident time on the ocular surface due to tear turnover, frequent topical applications and dependence on patient compliance, are the main drawbacks associated with topical administration. Nanotechnology-based medicine has emerged to circumvent these limitations, by encapsulating the drugs and preventing them from degradation and therefore providing sustained and contr

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Luiza Ribeiro de Souza, Ana, Charlene Priscila Kiill, Fernanda Kolenyak dos Santos, et al. "Nanotechnology-based Drug Delivery Systems for Dermatomycosis Treatment." Current Nanoscience 8, no. 4 (2012): 512–19. http://dx.doi.org/10.2174/157341312801784311.

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Prajapati, Shiv C., Sunita Singh, Bhupendra Singh, Mukul Sengar, and Vinay Mishra. "Nanotechnology-based Intranasal Drug Delivery Systems: A Review." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 472–80. http://dx.doi.org/10.25258/ijddt.14.1.66.

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An experimental study has focused on developing a different approach to systemic oral along with parenteral administration in order to overcome their common drawbacks, including hepatic first-pass, which reduces drug bioavailability following oral administration, off-target effects, low patient compliance, along with a slow onset of pharmacological action through first-aid cases. Novel drug delivery systems (DDS), mostly composed of polymers and biocompatible lipid materials, have significantly boosted this sector in recent years. The previously intranasal (IN) method of delivery is an accepta

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Gupta, Purnima, Evelyn Garcia, Amrita Sarkar, et al. "Nanoparticle Based Treatment for Cardiovascular Diseases." Cardiovascular & Hematological Disorders-Drug Targets 19, no. 1 (2019): 33–44. http://dx.doi.org/10.2174/1871529x18666180508113253.

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Nanotechnology has gained increased attention for delivering therapeutic agents effectively to the cardiovascular system. Heart targeted nanocarrier based drug delivery is a new, effective and efficacious approach for treating various cardiac related disorders such as atherosclerosis, hypertension, and myocardial infarction. Nanocarrier based drug delivery system circumvents the problems associated with conventional drug delivery systems, including their nonspecificity, severe side effects and damage to the normal cells. Modification of physicochemical properties of nanocarriers such as size,

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Pankaj, Khuspe* Kishori Kokate Trushali Mandhare Priyanka Nangre Balmukund Rathi. "A COMPREHENSIVE REVIEW ON NOVEL PHARMACEUTICAL NANOTECHNOLOGY AND ITS APPLICATIONS." Indo American Journal of Pharmaceutical Sciences 04, no. 12 (2017): 4640–47. https://doi.org/10.5281/zenodo.1123248.

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The health care industry is one ofhuge part of world industries today. With such a huge customer based and an increasing demand, pharmaceutical industries will respond to patient’s demands by developing and successfully expanding their technologies. The nature of newly discovered drugs becomes more complex and toxicity also increased, new novel modes of delivery are necessary to deliver them to the desired sites of the body. Due to this reason the renowned pharmaceutical companies are concentrating on applying new methods and technologies. As compared to other technologies pharmaceutical

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Brenckman, Christina, Samiha Hossain, and Nuggehalli M. Ravindra. "Nanotechnology-based drug delivery systems for treatment of knee injuries and Alzheimer’s disease – a review." Material Science & Engineering International Journal 7, no. 4 (2023): 166–79. http://dx.doi.org/10.15406/mseij.2023.07.00220.

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The effective treatment of human illnesses relies on the ability to deliver therapeutic compounds to diseased sites in a highly efficient manner. However, conventional therapeutic strategies often require high systemic administration due to non-specific biodistribution and rapid metabolism of free drug molecules before they can reach their intended targets which leads to undesirable side effects. Nanotechnology offers a solution to mitigate these issues by allowing the development of drug delivery systems (DDS) within the nanometer size range, which can alter the pharmacological and therapeuti

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Thangam, C., Rozario Cyril, R. Jayasree, Y. Santhosh Kumar, Langeswaran Kulanthaivel, and Gowtham Kumar Subbaraj. "Enhancement of Oral Bioavailability of Drugs through Nanotechnology: Comprehensive Review and Meta-Analysis." Journal of Preventive, Diagnostic and Treatment Strategies in Medicine 2, no. 4 (2023): 187–93. http://dx.doi.org/10.4103/jpdtsm.jpdtsm_116_23.

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In terms of drug delivery methods, oral administration stands out as the preferred option, as it ensures better patient compliance. However, the challenges of poor water solubility and limited metabolic/enzymatic stability hinder the effectiveness of oral drug delivery. Nanotechnology-based drug delivery systems offer promising solutions to overcome these barriers and enhance oral medication delivery. They provide an avenue for administering antihypertensive drugs with improved therapeutic impact and bioavailability. To compile information on enhancing oral bioavailability through nanotechnolo

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Pozharov, Vitaly P., and Tamara Minko. "Nanotechnology-Based RNA Vaccines: Fundamentals, Advantages and Challenges." Pharmaceutics 15, no. 1 (2023): 194. http://dx.doi.org/10.3390/pharmaceutics15010194.

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Over the past decades, many drugs based on the use of nanotechnology and nucleic acids have been developed. However, until recently, most of them remained at the stage of pre-clinical development and testing and did not find their way to the clinic. In our opinion, the main reason for this situation lies in the enormous complexity of the development and industrial production of such formulations leading to their high cost. The development of nanotechnology-based drugs requires the participation of scientists from many and completely different specialties including Pharmaceutical Sciences, Medi

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Siafaka, Panoraia I., Gökce Mutlu, and Neslihan Ü. Okur. "Alzheimer’s Disease and its Related Dementia Types: A Review on Their Management Via Nanotechnology Based Therapeutic Strategies." Current Alzheimer Research 17, no. 14 (2021): 1239–61. http://dx.doi.org/10.2174/1567205018666210218160812.

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Background: Dementia and its related types such as Alzheimer’s disease, vascular dementia and mixed dementia belong to brain associated diseases, resulting in long-term progressive memory loss. These diseases are so severe that can affect a person's daily routine. Up to date, treatment of dementia is still an unmet challenge due to their complex pathophysiology and unavailable efficient pharmacological approaches. The use of nanotechnology based pharmaceutical products could possibly improve the management of dementia given that nanocarriers could more efficiently deliver drugs to the brain. O

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Umapathy, Vidhya R., Prabhu M. Natarajan, and Bhuminathan Swamikannu. "Therapeutic Potential of Nanomaterial-based Drug Delivery." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 556–63. http://dx.doi.org/10.25258/ijddt.14.1.76.

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The medical market for sophisticated therapeutic medicine delivery systems is growing at a breakneck pace. There are many benefits to using nanotechnology and nanomaterials in treating chronic human illnesses, such as the ability to target the delivery of drugs to particular areas. Improving the therapeutic effectiveness of current and future medications might be as simple as creating new drug delivery methods. The prime applications related to nanomaterial drug delivery include immunotherapeutic agents, diagnostic testing, cancer therapy and nutraceutical delivery. Nanotechnology has the capa

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Er, Simge, Ushna Laraib, Rabia Arshad, et al. "Amino Acids, Peptides, and Proteins: Implications for Nanotechnological Applications in Biosensing and Drug/Gene Delivery." Nanomaterials 11, no. 11 (2021): 3002. http://dx.doi.org/10.3390/nano11113002.

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Over various scientific fields in biochemistry, amino acids have been highlighted in research works. Protein, peptide- and amino acid-based drug delivery systems have proficiently transformed nanotechnology via immense flexibility in their features for attaching various drug molecules and biodegradable polymers. In this regard, novel nanostructures including carbon nanotubes, electrospun carbon nanofibers, gold nanoislands, and metal-based nanoparticles have been introduced as nanosensors for accurate detection of these organic compounds. These nanostructures can bind the biological receptor t

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Swasthika, S.* Bhavyashree T. A. R. Shabaraya. "Cubosomes: A Novel Nanotechnology-Based Drug Delivery System for Osteoarthritis Treatment." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2907–14. https://doi.org/10.5281/zenodo.15450305.

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Osteoarthritis (OA) is a chronic joint disorder characterized by cartilage degradation, inflammation, and pain, leading to impaired mobility. Conventional treatments, such as NSAIDs, corticosteroids, and hyaluronic acid injections, often provide only temporary relief and are associated with systemic side effects. Cubosomes, self-assembled nanostructured lipid carriers, have emerged as a promising drug delivery system for OA treatment due to their biocompatibility, sustained drug release, and ability to encapsulate both hydrophilic and hydrophobic drugs. They offer targeted delivery of anti-inf

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Mittal, Khushi R., Nandini Pharasi, Bhavya Sarna, et al. "Nanotechnology-based drug delivery for the treatment of CNS disorders." Translational Neuroscience 13, no. 1 (2022): 527–46. http://dx.doi.org/10.1515/tnsci-2022-0258.

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Abstract Approximately 6.8 million people die annually because of problems related to the central nervous system (CNS), and out of them, approximately 1 million people are affected by neurodegenerative diseases that include Alzheimer’s disease, multiple sclerosis, epilepsy, and Parkinson’s disease. CNS problems are a primary concern because of the complexity of the brain. There are various drugs available to treat CNS disorders and overcome problems with toxicity, specificity, and delivery. Barriers like the blood–brain barrier (BBB) are a challenge, as they do not allow therapeutic drugs to c

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Nasiruddin, Mohammad, Md Kausar Neyaz, and Shilpi Das. "Nanotechnology-Based Approach in Tuberculosis Treatment." Tuberculosis Research and Treatment 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/4920209.

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Tuberculosis, commonly known as TB, is the second most fatal infectious disease after AIDS, caused by bacterium calledMycobacterium tuberculosis. Prolonged treatment, high pill burden, low compliance, and stiff administration schedules are factors that are responsible for emergence of MDR and XDR cases of tuberculosis. Till date, only BCG vaccine is available which is ineffective against adult pulmonary TB, which is the most common form of disease. Various unique antibodies have been developed to overcome drug resistance, reduce the treatment regimen, and elevate the compliance to treatment. T

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Om, Chiddarwar*. "The Role of Nanotechnology in Targeted Drug Delivery Systems for Cancer Treatment." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2888–95. https://doi.org/10.5281/zenodo.15450171.

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Nanotechnology has emerged as a transformative approach in cancer treatment through the development of targeted drug delivery systems. These systems utilize nanoparticles to deliver therapeutic agents precisely to cancer cells, thereby minimizing damage to healthy tissues and enhancing treatment efficacy. This review explores various nanocarriers, including liposomes, dendrimers, solid lipid nanoparticles, gold nanoparticles, and polymeric nanoparticles, highlighting their mechanisms and clinical applications. Passive targeting, driven by the Enhanced Permeability and Retention (EPR) effect, a

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Jahanmahin, Ali, and Hassan Borji. "Nanotechnology-based Approaches for the Treatment of Toxocariasis: A Prospective Review." Journal of Veterinary Physiology and Pathology 2, no. 2 (2023): 12–19. http://dx.doi.org/10.58803/jvpp.v2i2.24.

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Toxocariasis, caused by Toxocara parasites, is a prevalent parasitic disease affecting millions of people worldwide. Conventional anthelmintic drugs for toxocariasis face challenges such as limited efficacy and potential adverse effects, necessitating exploring alternative therapeutic strategies. Nanotechnology has emerged as a promising approach for the treatment of toxocariasis. This prospective review provides an overview of the potential of nanotechnology in toxocariasis treatment and highlights critical advancements in the field. The current review aimed to provide an overview of toxocari

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-, Aditya Abaso Deokate, Sanika chandrakant Deokate -, Tejraj Popat Gawade -, Saurabh Bapu Sangale -, and Ulka Mote -. "Nanotechnology Based Alternative For The Topical Delivery Of Psoriasis." International Journal For Multidisciplinary Research 6, no. 5 (2024). http://dx.doi.org/10.36948/ijfmr.2024.v06i05.29591.

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Psoriasis, a chronic autoimmune disease, is characterized by patches of abnormal skin that are red, pink, or purple, dry, itchy, and scaly. It affects people of all ages, with peak onset between 32 and 52 years old. Psoriasis is classified into three main types: vulgaris, pustular, and inverse. Novel Drug Delivery Systems (NDDS) offer innovative approaches to deliver pharmaceutical substances to the body more effectively and safely. These systems aim to increase bioavailability, maintain therapeutic drug concentrations, and minimize toxicity. Several NDDS are being used for psoriasis treatment

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