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Journal articles on the topic 'Naphthyridines – Spectra'

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Published: 4 June 2021

Last updated: 4 February 2022

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1

Wormell, P., and A. R. Lacey. "Electronic spectra of the naphthyridines: 1,8-naphthyridine." Chemical Physics 118, no. 1 (1987): 71–89. http://dx.doi.org/10.1016/0301-0104(87)85037-1.

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2

Wormell, P., and A. R. Lacey. "Electronic spectra of the naphthyridines: 2,7-naphthyridine." Chemical Physics 160, no. 1 (1992): 55–72. http://dx.doi.org/10.1016/0301-0104(92)87091-m.

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3

Gronowitz, Salo, Johan Malm, and Anna-Britta Hörnfeldt. "Synthesis of the six isomeric thieno[c]-fused 1,5- and 1,6-naphthyridines." Collection of Czechoslovak Chemical Communications 56, no. 11 (1991): 2340–51. http://dx.doi.org/10.1135/cccc19912340.

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trough the use of Pd(0)-catalyzed coupling between 2- and 4-formyl-3-thiopheneboronic acids and 3-amino-2-bromopyridine and 4-acetamido-3-bromopyridine, convenient one-pot procedures for the preparation of thieno[2,3-c]-1,5-naphthyridine, thieno[3,4-c]-1,5-naphthyridine, thieno-[2,3-c]-1,6-naphthyridine, and thieno[3,4-c]-1,6-naphthyridine have been developed. In order to obtain thieno[3,2-c]-1,6-naphthyridine 2-(tributylstannyl)-3-thiophene aldehyde had to be used, since the organometallic partner in the coupling reaction, 3-formyl-2-thipheneboronic acid, is too easily deboronated. The effect

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4

Chary, Maringanti Thirumala, Kaleru Mogilaiah, and Bathula Sreenivasulu. "Synthesis of 2-methyl-3-(5-phenyl or 1,5-diphenyl-2-pyrazolin-3-yl)-1,8-naphthyridines." Collection of Czechoslovak Chemical Communications 53, no. 7 (1988): 1543–48. http://dx.doi.org/10.1135/cccc19881543.

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3-Cinnamoyl-2-methyl-1,8-naphthyridines II have been synthesized utilizing Claisen-Schmidt condensation of 3-acetyl-2-methyl-1,8-naphthyridine I with aromatic aldehydes. The cinnamoyl naphthyridines react with hydrazine hydrate and phenylhydrazine to create the corresponding pyrazolinyl 1,8-naphthyridine derivatives (III and IV). The structures II-IV have been confirmed by their elemental analyses and spectral data. Some of the compounds have been screened for their fungicidal activity.

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5

Björk, Patrick, Anna-Britta Hörnfeldt, and Salo Gronowitz. "The syntheses and NMR spectra of the twelve isomeric thieno[b]fused naphthyridines." Journal of Heterocyclic Chemistry 31, no. 5 (1994): 1161–69. http://dx.doi.org/10.1002/jhet.5570310511.

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6

Mogilaiah, Kaleru, Kamreddy Rajendar Reddy, Gurram Rama Rao, and Bathula Sreenivasulu. "Synthesis of 2-methyl-3-(1-aryl-1H-tetrazol-5-yl)-1,8-naphthyridines." Collection of Czechoslovak Chemical Communications 53, no. 7 (1988): 1539–42. http://dx.doi.org/10.1135/cccc19881539.

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2-Methyl-3-(1-aryl-1H-tetrazol-5-yl)-1,8-naphthyridines III have been synthesized by the reaction of 2-methyl-N-aryl-1,8-naphthyridine-3-carboxyamides (I) with phosphorus pentachloride and azidolysis of the resulting imidoyl chlorides. Structures of these compounds have been established by means of their elemental analyses and spectral data.

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7

BJOERK, P., A. B. HOERNFELDT, and S. GRONOWITZ. "ChemInform Abstract: The Syntheses and NMR Spectra of the Twelve Isomeric Thieno(b)fused Naphthyridines." ChemInform 26, no. 14 (2010): no. http://dx.doi.org/10.1002/chin.199514170.

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8

Malm, Johan, Bengt Rehn, Anna-Britta Hörnfeldt, and Salo Gronowitz. "Synthesis and nmr spectra of the six isomeric thieno[c]-fused 1,7- and 1,8-naphthyridines." Journal of Heterocyclic Chemistry 31, no. 1 (1994): 11–15. http://dx.doi.org/10.1002/jhet.5570310102.

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9

MALM, J., B. REHN, A. B. HOERNFELDT, and S. GRONOWITZ. "ChemInform Abstract: Synthesis and NMR Spectra of the Six Isomeric Thieno(c)-fused 1,7- and 1,8-Naphthyridines." ChemInform 26, no. 11 (2010): no. http://dx.doi.org/10.1002/chin.199511168.

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10

KUNDENAPALLY, RAMALINGAM, RAMESH DOMALA, and B. SREENIVASULU. "Regioselective Synthesis of Novel [N-(4-Oxo-3-(2-phenyl-1,8-naphthyridin-3-yl)-thiazolidin-2-ylidene)]acetamide/benzamides and their Biological Activity." Asian Journal of Chemistry 31, no. 6 (2019): 1246–50. http://dx.doi.org/10.14233/ajchem.2019.21881.

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In an attempt to discover the new antibacterial agents to fight the bacterial infections, a series of 1,8-naphthyridine based 2-iminothiazolidin-4-one derivatives was synthesized by a straight-forward regioselective synthesis. 2-Phenyl-1,8-naphthyridin-3-amine (2) was reacted with acetyl or aroyl isothiocyantes to give the corresponding N-[(2-phenyl-1,8-naphthyridin-3-yl)carbamothioyl)]acetamide or benzamides (3a-e). Finally, the target compounds [N-(4-oxo-3-(2-phenyl-1,8-naphthyridin-3-yl)thiazolidin-2-ylidene)]acetamide or benzamides (4a-e) were obtained by the reaction of thiourea (3a-e) wi

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11

Chi, Shao-Ming, Yu-Fei Wang, Xin Gan, De-Hui Wang, and Wen-Fu Fu. "Synthesis, structures, and spectroscopic properties of copper(I) complexes bearing 7-acetamido-4-methyl-1,8-naphthyridin-2-carbaldehyde azine and 1,2-bis(diphenylphosphino)ethane ligands." Open Chemistry 7, no. 4 (2009): 923–28. http://dx.doi.org/10.2478/s11532-009-0087-y.

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AbstractA new ligand napaa (napaa = 7-acetamido-4-methyl-1,8-naphthyridin-2-carbaldehyde azine) and its two dinuclear copper(I) complexes, Cu2(napaa)(dppe)2(ClO4)2 (1) and Cu2(napaa)(PPh3)4(BF4)2 (2) (dppe = 1,2-bis(diphenylphosphino)ethane) and PPh3 = triphenylphosphine) were synthesized and characterized, and the structure of 1 was determined by X-ray crystal analysis. Each copper atom in 1 has a distorted tetrahedral geometry in which the metal center is associated to napaa and dppe ligands displaying chelating coordination modes and the naphthyridine rings of napaa are almost coplanar. The

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12

Tucker, Sheryl A., William E. Acree, and Christopher Upton. "Polycyclic Aromatic Nitrogen Heterocycles. Part V: Fluorescence Emission Behavior of Select Tetraaza- and Diazaarenes in Nonelectrolyte Solvents." Applied Spectroscopy 47, no. 2 (1993): 201–6. http://dx.doi.org/10.1366/0003702934048235.

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Fluorescence emission spectra are reported for tricycloquinazoline, dibenzo[c,f][2,7]naphthyridine, dibenzo[a,c]phenazine, dibenz[b,h]-indeno[1,2,3de][1,6]naphthyridine, and dibenz[c,f]indeno[l,2,3ij]-[2,7]naphthyridine dissolved in organic nonelectrolyte solvents of varying polarity and acidity. Results of these experiments were used to screen PANHs for potential probe character. The effect of nitromethane as a selective quenching agent on both the unprotonated and protonated PANHs was also examined. Nitromethane was found to quench fluorescence emission of dibenzo[c,f][2,7]naphthyridine. Emi

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13

Rama Rao, Gurram, Kaleru Mogilaiah, and Bathula Sreenivasulu. "Synthesis of 2-(4-aryl-2-pyrazolin-3-yl)-1,8-naphthyridines by 1,3-dipolar cycloaddition." Collection of Czechoslovak Chemical Communications 54, no. 6 (1989): 1716–20. http://dx.doi.org/10.1135/cccc19891716.

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2-(4-Aryl-2-pyrazolin-3-yl)-1,8-naphthyridines III have been prepared by the cycloaddition of diazomethane to 2-styryl-1,8-naphthyridines II. The structures of the compounds have been confirmed by elemental analyses and spectral data. All these compounds have been screened for fungicidal activity.

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14

Gou, Gao Zhang, Bo Zhou, Ling Shi, Xian Lan Chen, Na Wu та Wei Liu. "Synthesis, Spectroscopic Properties of Bis-Boc-L-Alanine Modiﬁed 1,8-Naphthyridine Ligand Induced by Hg²⁺". Advanced Materials Research 1089 (січень 2015): 121–24. http://dx.doi.org/10.4028/www.scientific.net/amr.1089.121.

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One Bis-Boc-L-alanine-1,8-naphthyridine ligand containing amino acid by amido bond named 2,7-Bis-Boc-L-alanine-1,8-naphthyridine (L1) was synthesized and characterized. And there absorption and fluorescence spectra in methanol is presented. It exhibits electronic absorption spectra with λmax at about 340 nm, which can be tentatively assigned to π→π* transition. The emission spectra of L1 in CH3OH shows a mirror symmetry peak with λmax at about 375 nm. Then, the comprehensive study of spectroscopic properties upon titration of L1 with heavy metal ions as ion source in CH3OH was investigated.

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15

Barbu, Eugen, Dan Mihaiescu, and Flavian Cuiban. "Spectral Characteristics of 2,7-Naphthyridines." Molecules 5, no. 12 (2000): 956–60. http://dx.doi.org/10.3390/50700956.

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16

Gou, Gao Zhang, Bo Zhou, Ling Shi, Na Wu, Xian Lan Chen, and Wei Liu. "Synthesis, Spectroscopic Properties of Bis-Boc-L-alanine Modified 1,8-Naphthyridine Ligand Induced by Cr³⁺." Applied Mechanics and Materials 716-717 (December 2014): 163–66. http://dx.doi.org/10.4028/www.scientific.net/amm.716-717.163.

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One Bis-Boc-L-alanine-1,8-naphthyridine ligand containing amino acid by amido bond named 2,7-Bis-Boc-L-alanine-1,8-naphthyridine (L1) was synthesized and characterized. And there absorption and fluorescence spectra in methanol is presented. Then, the comprehensive study of spectroscopic properties upon titration of L1 with heavy metal ions as ion source in CH3OH was investigated. It shows compound L1 can use as a fluorescent probe for heavy metal ions like Cr3+.

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17

Journal, Baghdad Science. "Synthesis and biological studies for some heterocyclic compounds derived from 2-Morpholino-1,8- naphthyridine-4-carboxylic acid." Baghdad Science Journal 10, no. 3 (2013): 758–65. http://dx.doi.org/10.21123/bsj.10.3.758-765.

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New heterocyclic compounds derived from 2-Morpholino-1,8-naphthyridine-4-carboxylic acid such as oxadiazolo, thiadiazolo – thione and triazolo-thione have been prepared and characterized on the basis of IR and 1H NMR spectra data. The hydrizide compound was utilized as a starting material for preparing of these compounds. The second part of this study involves the biological studies of some of these naphthyridine derivatives by using three different kinds of bacteria namely: Staphylococcus aureus, Pseudomonas aeruglnosa and Escherichia coli. The data indicated that some of these compounds have

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18

Journal, Baghdad Science. "Synthesis of some heterocyclic derivatives of 1,8-Naphthyridine with a new substitution on the Naphthyridine ring." Baghdad Science Journal 10, no. 3 (2013): 749–57. http://dx.doi.org/10.21123/bsj.10.3.749-757.

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Abstract The Synthesis in good yields of some new 1,8-Naphthyridine derivatives (1-9) and characterized on the basis of IR and 1H NMR spectra data. The compounds (1) and (6) were utilized as a starting material for the preparing of these compounds.

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19

Reddy, Kamreddy Rajendar, Kaleru Mogilaiah, and Bathula Sreenivasulu. "Synthesis of 6-aryl-6H-naphtho[2’,1’:5,6]pyrano[4,3-b]-[1,8]naphthyridines." Collection of Czechoslovak Chemical Communications 53, no. 3 (1988): 643–45. http://dx.doi.org/10.1135/cccc19880643.

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A series of new 6-aryl-6H-naphtho[2’,1’:5,6]pyrano[4,3-b][1,8]naphthyridines III have been synthesized by condensing 2-aminonicotinaldehyde (I) with a number of 1-hydroxy-2-naphthyl styryl ketones II in the presence of glacial acetic acid containing a catalytic amount of conc. sulphuric acid. The products have been characterized on the basis of elemental analyses and spectral data. Antibacterial activity of these compounds is negligible.

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20

Monkowius, U., Y. N. Svartsov, T. Fischer, M. Zabel, and H. Yersin. "Synthesis, crystal structures, and electronic spectra of (1,8-naphthyridine)ReI(CO)3Cl and [(1,8-naphthyridine)CuI(DPEPhos)]PF6." Inorganic Chemistry Communications 10, no. 12 (2007): 1473–77. http://dx.doi.org/10.1016/j.inoche.2007.09.010.

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21

Bhat, Sheeraz Ahmad, and Shabbir Ahmad. "Quantum chemical and spectroscopic investigations of 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid." Journal of Theoretical and Computational Chemistry 15, no. 05 (2016): 1650042. http://dx.doi.org/10.1142/s0219633616500425.

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The FTIR (4000–400[Formula: see text]cm[Formula: see text]) and the FT-Raman spectra (4000–50[Formula: see text]cm[Formula: see text]) of 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid are recorded and investigated. The spectra are interpreted using anharmonic frequency computations by VPT2, VSCF and PT2-VSCF methods within DFT/6-311G(d,p) framework. The root mean square (RMS) values indicate that VSCF computed frequencies are in close agreement with the observed frequencies. The combination and overtone bands are also identified in the FTIR spectrum. The intermolecular O-H[Formula: se

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22

Oanh, Nguyen Thi Tu, To Hai Tung, Cao Thi Hue, Le Nguyen Thanh, Do Thi Thao, and Nguyen Thi Minh Hang. "Two New Alkaloids from Polyalthia nemoralis." Natural Product Communications 12, no. 7 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200706.

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A new azaoxoaporphine alkaloid, 8,9-dimethoxysampangine (1), and a new naphthyridine alkaloid, 7-methoxy-8-hydroxyeupolauridine (2), along with two known azaoxoaporphine alkaloids, sampangine (3) and 9-methoxysampangine (4), were isolated from the EtOAc extract of the barks of Polyalthia nemoralis. Their structures were established on the basis of spectral evidences. Compound 1 exhibited significant cytotoxicity against KB, MCF7, LU-1, HepG2, LNCap, SW626 and SW480 cancer cell lines with IC50 values in the range of 5.06±0.04-7.61±0.06 μM.

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23

Husain, Asif, Munendra M. Varshney, Versha Parcha, Aftab Ahmad, and Shah A. Khan. "Nalidixic Acid Schiff Bases: Synthesis and Biological Evaluation." Letters in Drug Design & Discovery 15, no. 1 (2018): 103–11. http://dx.doi.org/10.2174/1570180814666170710160751.

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Background: The prevalence of morbidity and mortality due to infections from parasitic worms and protozoa is on rise especially in third world countries. The situation is further worsened by drug resistant microbial pathogens. Objectives: The antimicrobial and anthelmintic activities associated with substituted furfuraldehyde and 1,8-naphthyridine nucleus of nalidixic acid prompted us to synthesize some new quinolone Schiff bases with an aim to obtain potent antibacterial and anthelmintic agents with improved safety and efficacy. Methods: A new series of 1,8 naphthyridine based Schiff bases we

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24

Refat, Hala M., and Khaled S. Mohamed. "Efficient and convenient synthesis of pyrido [2,1-b]benzothiazole, pyrimidopyrido[2,1-b]benzothiazole and benzothiazolo[3,2-a][1,8]naphthyridine derivatives." Heterocyclic Communications 21, no. 4 (2015): 219–24. http://dx.doi.org/10.1515/hc-2015-0018.

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AbstractNew 3-aryl-pyrido[2,1-b][1,3]benzothiazole derivatives 2a–e were synthesized in excellent yields via the reaction of benzothiazoleacetonitrile (1) with different aromatic aldehydes. The treatment of 2-(benzo[d]thiazol-2-yl)-3-(pyridin-4-yl)acrylonitrile (6) with malononitrile afforded 1-amino-3-(pyridin-4-yl)-3H-pyrido[2,1-b][1,3]benzothiazole-2,4-dicarbonitrile (7), which was allowed to react with a variety of reagents to provide pyrimido[5′,4′:5,6]pyrido[2,1-b][1,3]benzothiazole 8, 9 and [1,3]benzothiazolo[3,2-a][1,8]naphthyridine 10, 15 derivatives. All synthesized products were con

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25

Griffith, William P., and Tse Yuen Koh. "SERS of 1,8-naphthyridine and the Raman spectra of two of its complexes." Journal of Raman Spectroscopy 26, no. 12 (1995): 1067–70. http://dx.doi.org/10.1002/jrs.1250261208.

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26

Matveeva, Anna G., Pavel S. Lemport, Larissa A. Leites, et al. "Lanthanide(III) complexes with phosphoryl containing 1,8-naphthyridine: Crystal structures and vibrational spectra." Inorganica Chimica Acta 362, no. 9 (2009): 3187–95. http://dx.doi.org/10.1016/j.ica.2009.02.023.

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27

Koraiem, Ahmed I., Islam M. Abdellah, Ahmed El-Shafei, Fathy F. Abdel-Latif, and Reda M. Abd El-Aal. "Synthesis, optical characterization, and TD-DFT studies of novel mero/bis-mero cyanine dyes based on N-Bridgehead heterocycles." Canadian Journal of Chemistry 97, no. 3 (2019): 219–26. http://dx.doi.org/10.1139/cjc-2018-0325.

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Novel mero/bis-mero cyanine dyes based on N-Bridgehead imidazo[1,2-g]quinolino[2,1-a][2,6]naphthyridine have been synthesized and characterized to evaluate intramolecular charge transfer (ICT) effect on the energy gap (E0-0). The UV–vis and emission spectral studies revealed that dyes are absorbed in the region of λmax 485–577 nm and emitted at 567–673 nm. Their solvatochromic behavior in solvents of various polarities, CCl4, C6H6, H2O, CHCl3, acetone, and DMF, was studied to emphasize the effect of solvent polarity on the absorption maxima, molar extinction coefficients of the dyes, and excit

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28

Tucker, Sheryl A., Hardjanti Darmodjo, William E. Acree, et al. "Polycyclic Aromatic Nitrogen Heterocycles. Part IV: Effect of Solvent Polarity, Solvent Acidity, Nitromethane and 1,2,4-Trimethoxybenzene on the Fluorescence Emission Behavior of Select Monoaza- and Diazaarenes." Applied Spectroscopy 46, no. 11 (1992): 1630–35. http://dx.doi.org/10.1366/0003702924926952.

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Fluorescence emission spectra are reported for naphth[2′l′8′7′: 4,10,5]anthra[l,9,8cdef]cinnoline, benzo[lmn][3,8]phenanthroline (also called 2,7-diazapyrene), benz[4,10]anthra[l,9,8cdef]cinnoline, naphtho[8,1,2hij]pyreno[9,10,ldef]phthalazine, acenaphtho[l,2b]pyridine, benzo[a]phenazine, indeno[l,2,3ij][2,7]naphthyridine, and indeno-[l,2,3ij]isoquinoline dissolved in organic nonelectrolyte solvents of varying polarity and acidity. Results of these measurements indicate that naphth[2′,1′,8′,7′:4,10,5]anthra[l,9,8cdef]cinnoline exhibits some signs of probe character as evidenced by changing emi

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29

Indirapriyadharshini, V. K., P. Ramamurthy, V. Raghukumar, and V. T. Ramakrishnan. "Spectral and photophysical properties of 1,6-naphthyridine derivatives: a new class of compounds for nonlinear optics." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 58, no. 8 (2002): 1535–43. http://dx.doi.org/10.1016/s1386-1425(01)00616-3.

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30

Urbanavičiūtė, Indrė, Sigita Višniakova, Justina Dirsytė, et al. "A series of new luminescent non-planar 1,8-naphthyridine derivatives giving coloured and close-to-white electroluminescence spectra." Journal of Luminescence 181 (January 2017): 299–309. http://dx.doi.org/10.1016/j.jlumin.2016.09.027.

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31

Osmialowski, Borys, Erkki Kolehmainen, Elina Sievanen, Reijo Kauppinen, and Babita Behera. "Secondary interactions as driving force in heterocomplex formation of 2,7-disubstituted-1,8-naphthyridines: Quantum chemical, NMR and mass spectral investigations." Journal of Molecular Structure 931, no. 1-3 (2009): 60–67. http://dx.doi.org/10.1016/j.molstruc.2009.05.028.

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32

Yu, Chung-Han, Min-Shiang Kuo, Ching-Yi Chuang, Gene-Hsiang Lee, Bih-Yaw Jin, and Shie-Ming Peng. "Chirality control of the Quadruple helixes of the metal strings." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1032. http://dx.doi.org/10.1107/s2053273314089670.

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Novel chiral pentadentate ligands with naphthyridine and camphorsulfonyl groups have been designed and used to control the chirality of quadruple helixes of metal strings directly:Δ-Ni5((-)camnpda)4 (1) and Λ-Ni5((+)camnpda)4 (2). Compound 1 is a Δ form metal string complex with H2(-)camnpda and 2 is Λ form one with H2(+)camnpda. By X-ray single-crystal diffraction, The structures of the compound 1 and 2 are both 2,2-trans form in the same monoclinic space group C2 and have the similar unit cell. Further, it demonstrates that two metal strings are chiral isomers each other by CD spectra. In th

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33

Guo, Ying, Yongcun Ding, Xingqiang Zhao, and Qingqing Liu. "Structural and electronic properties transitions induced by different pressures in crystalline nalidixic acid." International Journal of Modern Physics C 28, no. 12 (2017): 1750147. http://dx.doi.org/10.1142/s0129183117501479.

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In this work, a detailed study of the structural, electronic and absorption properties of crystalline 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid) in the pressure range 0–300[Formula: see text]GPa is performed by density functional theory (DFT) calculations. The detail analysis of the variation tendencies of the lattice constants, bond lengths and bond angles with increasing pressures shows that complex transformations occur in nalidixic acid under compression. In addition, it can be see that the [Formula: see text]- and [Formula: see text]-axes are m

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34

Chen, Yong, Wen-Fu Fu, Jun-Li Li, Xi-Juan Zhao, and Xue-Mei Ou. "Conformation impact on spectral properties of bis(5,7-dimethyl-1,8-naphthyridin-2-yl)amine and its ZnII complex." New Journal of Chemistry 31, no. 10 (2007): 1785. http://dx.doi.org/10.1039/b705149b.

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35

Eid, Elshimaa M., Huwaida ME Hassaneen, Samah A. Loutfy, and Taher Salaheldin. "Preparation of pyrimido[4,5-b][1,6]naphthyridin-4(1H)-one derivatives using a zeolite–nanogold catalyst and their in vitro evaluation as anticancer agent." Journal of Chemical Research 45, no. 7-8 (2021): 679–86. http://dx.doi.org/10.1177/1747519820988806.

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Catalysis using supported gold nanoparticles has attracted significant research interest due to their unique properties and potential that is directly related to their particle size. An efficient one-pot, three-component procedure is developed for the preparation of pyrimido[4,5- b][1,6]naphthyridin-4( 1H)-one derivatives (4a–h) by cyclocondensation of 6-amino-2-thioxo-2,3-dihydropyrimidin-4( 1H)-one (1), aromatic aldehydes (2), and 1-benzylpiperidin-4-one (3) in the presence of zeolite-nano Au as a green catalyst in ethanol at 80 °C. The presented methodology has a number of advantages includ

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36

Mizuki, Y., I. Fujiwara, T. Yamaguchi, and Y. Sekine. "Structure-related inhibitory effect of antimicrobial enoxacin and derivatives on theophylline metabolism by rat liver microsomes." Antimicrobial Agents and Chemotherapy 40, no. 8 (1996): 1875–80. http://dx.doi.org/10.1128/aac.40.8.1875.

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Enoxacin, an antimicrobial fluoroquinolone with a 7-piperazinyl-1, 8-naphthyridine skeleton, is a potent inhibitor of cytochrome P-450-mediated theophylline metabolism. The present study was designed to clarify, using seven enoxacin derivatives, the molecular characteristics of the fluoroquinolone responsible for the inhibition. Three derivatives with methyl-substituted 7-piperazine rings inhibited rat liver microsomal theophylline metabolism to 1,3-dimethyluric acid to an extent similar to that of enoxacin (50% inhibitory concentrations [IC50s] = 0.39 to 0.48 mM). 7-Piperazinyl-quinoline deri

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Swamy, Sreedasyam, Erra Reddy, Devunuri Raju, and Sunkari Jyothi. "Synthesis and Spectral Investigations of Manganese(II), Cobalt(II), Nickel(II), Copper(II) and Zinc(II) Complexes of New Polydentate Ligands Containing a 1,8-Naphthyridine Moiety." Molecules 11, no. 12 (2006): 1000–1008. http://dx.doi.org/10.3390/11121000.

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Behrens, Norah Barba, Graciela Müller Carrera, David M. L. Goodgame, Ann S. Lawrence, and David J. Williams. "Complexes of 5,7-dimethyl-1,8-naphthyridine-2-ol(dimenol): EPR spectra of an unusual copper(II) dimer containing dimenol and acetate bridges, and crystal structure of [Rh(O2CC3H7)2(dimenol)]2." Inorganica Chimica Acta 102, no. 2 (1985): 173–79. http://dx.doi.org/10.1016/s0020-1693(00)86756-0.

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Vasilin, Vladimir K., Eugeniya A. Kanishcheva, Tat’yana А. Stroganova, et al. "3-Amino(azido)-4,6-aryl(hetaryl)thieno[2,3-b]pyridines and benzo(furo,thieno)[c]thieno[2,3,4-i,j]-2,7-naphthyridines on their basis: synthesis, spectral properties, and prediction of biological activity." Chemistry of Heterocyclic Compounds 56, no. 8 (2020): 1078–91. http://dx.doi.org/10.1007/s10593-020-02777-3.

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Halim, Shimaa Abdel, and Magdy A. Ibrahim. "Synthesis, DFT calculations, electronic structure, electronic absorption spectra, natural bond orbital (NBO) and nonlinear optical (NLO) analysis of the novel 5-methyl-8H-benzo[h]chromeno[2,3-b][1,6] naphthyridine-6(5H),8-dione (MBCND)." Journal of Molecular Structure 1130 (February 2017): 543–58. http://dx.doi.org/10.1016/j.molstruc.2016.10.058.

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41

Khalil, Saied M. E. "SYNTHESIS AND SPECTRAL FEATURES OF Fe(III), Co(II), Ni(II), Cu(II), Zn(II), AND UO2(VI) COMPLEXES OF 3-FORMYL-4-HYDROXY-1,8- NAPHTHYRIDIN-2-ONE (OO) AND ITS ALDOXIME (ON)." Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 31, no. 3 (2001): 417–29. http://dx.doi.org/10.1081/sim-100002229.

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Deska, M., and W. Śliwa. "Syntheses, geometry optimization, and electronic structure of N-and C-substituted benzonaphthyridines." Chemical Papers 60, no. 1 (2006). http://dx.doi.org/10.2478/s11696-006-0006-z.

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AbstractSynthesis of N-and C-substituted derivatives of benzo[h][1,6]naphthyridine, bearing 2-hydroxyethyl group has been made by quaternization reaction and by condensation of corresponding methylbenzonaphthyridines with formaldehyde. For six derivatives of isomeric benzo[c][1,5]-, benzo[h][1,6]-, and benzo[f][1,7]naphthyridines the 13C NMR spectra are discussed.For ten compounds the geometry was optimized with the AM1 and, in one case also with the ab initio 6–31G method; their effective charge values have also been calculated.

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KUNDENAPALLY, RAMALINGAM, RAMESH DOMALA, and SREENIVASULU BATHULA. "SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL 5-ARYLIDENE-2-IMINO-3-(2- PHENYL- 1,8-NAPHTHYRIDIN-3-YL)THIAZOLIDIN-4-ONES." Asian Journal of Pharmaceutical and Clinical Research, June 21, 2019, 150–53. http://dx.doi.org/10.22159/ajpcr.2019.v12i18.34273.

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Objectives: Nowadays, antimicrobial resistance represents one of the most significant challenges in the medical community. To overcome the problem, it requires the discovery of newer safe and effective molecules against infectious sickness. Synthesis and screening of 1,8-naphthyridines have attracted much attention over the decades since it plays a key role against the microorganisms. Methods: 1,8-naphthyridine based 5-arylidene derivatives of thiazolidinone (3a-i) has been achieved by the cyclization reaction of 2-chloro-N- (2-phenyl-1,8-naphthyridin-3-yl)acetamide (1) with potassium th

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Deepa, H. R., J. Thipperudrappa, and H. M. Suresh Kumar. "Spectral Properties of Laser Dyes at varying Temperature." Canadian Journal of Physics, April 23, 2020. http://dx.doi.org/10.1139/cjp-2020-0087.

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Spectral properties of laser dyes 4-methyl-7-(4-morpholinyl)-2 H pyrano [2,3-b] pyridin-2-one (LD – 425) and 6,7,8,9-tetrahydro-6,8,9-trimethyl-4-(trifluoromrthyl)-2H-pyrano[2,3b][1,8]naphthyridin-2-one (LD – 489) have been investigated in the temperature range 250C - 650C by steady state and transient methods. Fluorescence intensity decreases with increase in temperature with fluorescence band maxima shifted towards shorter wavelength in both the dyes. Further, fluorescence lifetime has decreased with increase in temperature for LD - 425, whereas remained constant with change in temperature f

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Rajković, Snežana, Andjela A. Franich, Vojislav Ćupurdija, and Marija D. Živković. "DNA-and BSA-Binding Studies of Dinuclear Palladium(II) Complexes with 1,5-Naphtiridine Bridging Ligands." Serbian Journal of Experimental and Clinical Research, June 22, 2021. http://dx.doi.org/10.2478/sjecr-2021-0030.

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Abstract The interactions of metal complexes with important biomolecules such as deoxyribonucleic acid (DNA) or bovine serum albumin (BSA) are responsible for their antitumor activity due to different modes of interaction with DNA and their transport through the blood system to cells and tissues via serum albumin. Therefore, the dinuclear palladium(II) complexes, [{Pd(en)Cl}2(μ-1,5- nphe)](NO3)2 (Pd1) and [{Pd(1,3-pd)Cl}2(μ-1,5-nphe)](NO3)2 (Pd2) (en is ethylenediamine, 1,3-pd is 1,3-propylenediamine and 1,5-nphe is the bridging 1,5-naphthyridine ligand) were synthesized and characterized by d

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BARBA BEHRENS, N., G. MUELLER CARRERA, D. M. L. GOODGAME, A. S. LAWRENCE, and D. J. WILLIAMS. "ChemInform Abstract: Complexes of 5,7-Dimethyl-1,8-naphthyridine-2-ol(dimenol): EPR Spectra of an Unusual Copper(II) Dimer Containing Dimenol und Acetate Bridges, and Crystal Structure of [Rh(O2CC3H7)2(dimenol)]2." Chemischer Informationsdienst 16, no. 47 (1985). http://dx.doi.org/10.1002/chin.198547268.

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EZELL, E. L., R. P. THUMMEL, and G. E. MARTIN. "ChemInform Abstract: CORRELATION OF RESONANCES OF STRONGLY COUPLED SPIN SYSTEMS VIA RESPONSES DUE TO STRONG COUPLING IN HOMONUCLEAR TWO-DIMENSIONAL J-RESOLVED SPECTRA: TOTAL ASSIGNMENT OF THE PROTON-NMR SPECTRUM OF 2-(2′-PYRIDYL)-1,8-NAPHTHYRIDINE." Chemischer Informationsdienst 16, no. 1 (1985). http://dx.doi.org/10.1002/chin.198501218.

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